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ONTOLOGY REPORT - ANNOTATIONS


Term:1-hydroxy-2-naphthoic acid
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Accession:CHEBI:36108 term browser browse the term
Definition:A naphthoic acid with the carboxy group at position 2 and carrying a hydroxy substituent at the 1-position. It is a xenobiotic metabolite produced by the biodegradation of phenanthrene by microorganisms.
Synonyms:related_synonym: 1-Naphthol-2-carboxylic acid;   1-hydroxy-2-naphthalenecarboxylic acid;   1-hydroxynaphthalene-2-carboxylic acid;   2-carboxy-1-naphthol;   Formula=C11H8O3;   InChI=1S/C11H8O3/c12-10-8-4-2-1-3-7(8)5-6-9(10)11(13)14/h1-6,12H,(H,13,14);   InChIKey=SJJCQDRGABAVBB-UHFFFAOYSA-N;   SMILES=OC(=O)c1ccc2ccccc2c1O
 alt_id: CHEBI:19050;   CHEBI:634
 xref: Beilstein:974438 "Beilstein";   CAS:86-48-6 "ChemIDplus";   CAS:86-48-6 "KEGG COMPOUND";   Gmelin:721746 "Gmelin";   KEGG:C03203
 xref_mesh: MESH:C050175
 xref: PMID:1650428 "Europe PMC";   PMID:17305248 "Europe PMC";   PMID:23539472 "Europe PMC";   PMID:23582404 "Europe PMC";   PMID:23997334 "Europe PMC";   PMID:25643723 "Europe PMC";   Patent:US7358391;   Reaxys:974438 "Reaxys"
 cyclic_relationship: is_conjugate_acid_of CHEBI:15992


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1-hydroxy-2-naphthoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:6480464
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 JBrowse link 8 62,472,087 62,478,122 RGD:6480464
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 JBrowse link 6 2,308,179 2,316,739 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mapk8 mitogen-activated protein kinase 8 JBrowse link 16 9,620,854 9,709,342 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        biochemical role 19147
          metabolite 19115
            xenobiotic metabolite 13813
              2-naphthoic acid 14
                1-hydroxy-2-naphthoic acid 12
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        aromatic carboxylic acid 10703
                                          naphthoic acid 43
                                            2-naphthoic acid 14
                                              1-hydroxy-2-naphthoic acid 12
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.