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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cyclohexanecarboxylic acid
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Accession:CHEBI:36096 term browser browse the term
Definition:A monocarboxylic acid that consists of cyclohexane substituted by a carboxy group.
Synonyms:related_synonym: Cyclohexancarbonsaeure;   Cyclohexane-1-carboxylate;   Formula=C7H12O2;   Hexahydrobenzoic acid;   InChI=1S/C7H12O2/c8-7(9)6-4-2-1-3-5-6/h6H,1-5H2,(H,8,9);   InChIKey=NZNMSOFKMUBTKW-UHFFFAOYSA-N;   SMILES=OC(=O)C1CCCCC1;   carboxycyclohexane;   cyclohexanoic acid;   cyclohexylcarboxylic acid;   cyclohexylformic acid;   cyclohexylmethanoic acid
 alt_id: CHEBI:23477;   CHEBI:36082;   CHEBI:4012
 xref: Beilstein:970529;   CAS:98-89-5;   Gmelin:50010;   HMDB:HMDB0031342;   KEGG:C09822;   KNApSAcK:C00000334;   PMID:21459409;   Wikipedia:Cyclohexanecarboxylic_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:27804


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tranexamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Tranexamic Acid inhibits the reaction [Rotenone results in increased expression of BAX protein] CTD PMID:19539006 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Tranexamic Acid inhibits the reaction [Rotenone results in decreased expression of BCL2 protein] CTD PMID:19539006 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO Tranexamic Acid inhibits the reaction [Rotenone results in increased cleavage of and results in increased activity of CASP3 protein] CTD PMID:19539006 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions ISO Tranexamic Acid inhibits the reaction [Rotenone results in increased cleavage of CASP9 protein] CTD PMID:19539006 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO Tranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of COL1A1 mRNA] CTD PMID:24633426 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Krt19 keratin 19 multiple interactions ISO Tranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of KRT19 protein] CTD PMID:24633426 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Tranexamic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:19539006 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO Tranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TGFB2 mRNA] CTD PMID:24633426 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO Tranexamic Acid inhibits the reaction [1-Naphthylisothiocyanate results in increased expression of TIMP1 mRNA] CTD PMID:24633426 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    role 19734
      chemical role 19250
        donor 18378
          Bronsted acid 18241
            oxoacid 18193
              carbon oxoacid 18073
                carboxylic acid 18061
                  monocarboxylic acid 17407
                    cyclohexanecarboxylic acid 9
                      (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylic acid 0
                      (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylic acid 0
                      1-amino-1-cyclohexanecarboxylic acid 0
                      2-hydroxy-4-isopropenylcyclohexanecarboxylic acid + 0
                      2-hydroxycyclohexanecarboxylic acid + 0
                      2-oxocyclohexanecarboxylic acid + 0
                      4-oxocyclohexanecarboxylic acid 0
                      N-[5-(1-naphthylmethyl)-1,3-thiazol-2-yl]cyclohexanecarboxamide 0
                      cyclohexane-1-carbonyl-CoA + 0
                      cyclohexanecarboxylate ester + 0
                      tranexamic acid 9
                      trans-4-hydroxycyclohexanecarboxylic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        monocarboxylic acid 17407
                                          cyclohexanecarboxylic acid 9
                                            (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylic acid 0
                                            (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylic acid 0
                                            1-amino-1-cyclohexanecarboxylic acid 0
                                            2-hydroxy-4-isopropenylcyclohexanecarboxylic acid + 0
                                            2-hydroxycyclohexanecarboxylic acid + 0
                                            2-oxocyclohexanecarboxylic acid + 0
                                            4-oxocyclohexanecarboxylic acid 0
                                            N-[5-(1-naphthylmethyl)-1,3-thiazol-2-yl]cyclohexanecarboxamide 0
                                            cyclohexane-1-carbonyl-CoA + 0
                                            cyclohexanecarboxylate ester + 0
                                            tranexamic acid 9
                                            trans-4-hydroxycyclohexanecarboxylic acid 0
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