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ONTOLOGY REPORT - ANNOTATIONS


Term:4-coumaric acid
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Accession:CHEBI:36090 term browser browse the term
Definition:A coumaric acid in which the hydroxy substituent is located at C-4 of the phenyl ring.
Synonyms:exact_synonym: 3-(4-hydroxyphenyl)prop-2-enoic acid
 related_synonym: 3-(4-hydroxyphenyl)-2-propenoic acid;   3-(4-hydroxyphenyl)acrylic acid;   4-hydroxycinnamic acid;   Formula=C9H8O3;   InChI=1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12);   InChIKey=NGSWKAQJJWESNS-UHFFFAOYSA-N;   SMILES=[H]C(=Cc1ccc(O)cc1)C(O)=O;   beta-[4-hydroxyphenyl]acrylic acid;   p-coumaric acid;   p-hydroxycinnamic acid;   p-hydroxyphenylacrylic acid;   para-coumaric acid
 alt_id: CHEBI:20348;   CHEBI:20405
 xref: Beilstein:2207381 "Beilstein";   CAS:7400-08-0 "ChemIDplus";   CAS:7400-08-0 "NIST Chemistry WebBook"
 xref_mesh: MESH:C032171
 xref: PMID:11684179 "Europe PMC";   PMID:19089825 "Europe PMC";   PMID:19930809 "Europe PMC";   PMID:22447332 "Europe PMC";   PMID:22585412 "Europe PMC";   PMID:22923003 "Europe PMC";   PMID:23178520 "Europe PMC";   PMID:23420453 "Europe PMC";   PMID:23485470 "Europe PMC";   PMID:23669407 "Europe PMC";   PMID:23684599 "Europe PMC";   PMID:23810795 "Europe PMC";   PMID:23857900 "Europe PMC";   PMID:23892112 "Europe PMC";   PMID:24927550 "Europe PMC";   PMID:7285584 "Europe PMC";   Wikipedia:4-coumaric_acid
 cyclic_relationship: is_conjugate_acid_of CHEBI:32373


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bisdemethoxycurcumin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcc1 ATP binding cassette subfamily C member 1 JBrowse link 10 549,537 672,235 RGD:6480464
G Abcc2 ATP binding cassette subfamily C member 2 JBrowse link 1 263,554,426 263,612,556 RGD:6480464
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Gclm glutamate cysteine ligase, modifier subunit JBrowse link 2 225,827,504 225,847,876 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Keap1 Kelch-like ECH-associated protein 1 JBrowse link 8 22,250,518 22,259,868 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mgat3 beta-1,4-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase JBrowse link 7 121,394,541 121,436,935 RGD:6480464
G Mmp14 matrix metallopeptidase 14 JBrowse link 15 33,074,441 33,083,666 RGD:6480464
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Msr1 macrophage scavenger receptor 1 JBrowse link 16 56,817,714 56,900,025 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:6480464
G Plau plasminogen activator, urokinase JBrowse link 15 3,644,296 3,650,765 RGD:6480464
G Pparg peroxisome proliferator-activated receptor gamma JBrowse link 4 147,274,055 147,399,383 RGD:6480464
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Timp2 TIMP metallopeptidase inhibitor 2 JBrowse link 10 107,338,465 107,386,072 RGD:6480464
G Tlr2 toll-like receptor 2 JBrowse link 2 182,840,171 182,846,061 RGD:6480464
G Tlr3 toll-like receptor 3 JBrowse link 16 50,016,466 50,031,011 RGD:6480464
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vdr vitamin D receptor JBrowse link 7 139,344,452 139,394,138 RGD:6480464
G Wt1 WT1 transcription factor JBrowse link 3 95,133,221 95,180,574 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        biochemical role 19138
          metabolite 19106
            eukaryotic metabolite 18748
              plant metabolite 17044
                4-coumaric acid 30
                  2-(p-coumaroyl)malic acid 0
                  3-(2-methoxyphenyl)-2-propenoic acid 0
                  3-p-coumaroylquinic acid 0
                  4-O-beta-D-glucosyl-4-coumaric acid + 0
                  4-coumaroyl-CoA + 0
                  4-p-coumaroylquinic acid 0
                  5-p-coumaroylquinic acid 0
                  7-O-(6-p-coumaroylglucosyl)chrysoeriol 0
                  bisdemethoxycurcumin 30
                  cadabicine sulfate 0
                  cis-4-coumaric acid + 0
                  p-coumaroylagmatine + 0
                  p-coutaric acid + 0
                  spermidine hydroxycinnamic acid conjugate + 0
                  trans-4-coumaric acid + 0
                  tricoumaroyl spermidine 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        monocarboxylic acid 17256
                                          alpha,beta-unsaturated monocarboxylic acid 11261
                                            cinnamic acids 2352
                                              hydroxycinnamic acid 1231
                                                monohydroxycinnamic acid 901
                                                  coumaric acid 30
                                                    4-coumaric acid 30
                                                      2-(p-coumaroyl)malic acid 0
                                                      3-(2-methoxyphenyl)-2-propenoic acid 0
                                                      3-p-coumaroylquinic acid 0
                                                      4-O-beta-D-glucosyl-4-coumaric acid + 0
                                                      4-coumaroyl-CoA + 0
                                                      4-p-coumaroylquinic acid 0
                                                      5-p-coumaroylquinic acid 0
                                                      7-O-(6-p-coumaroylglucosyl)chrysoeriol 0
                                                      bisdemethoxycurcumin 30
                                                      cadabicine sulfate 0
                                                      cis-4-coumaric acid + 0
                                                      p-coumaroylagmatine + 0
                                                      p-coutaric acid + 0
                                                      spermidine hydroxycinnamic acid conjugate + 0
                                                      trans-4-coumaric acid + 0
                                                      tricoumaroyl spermidine 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.