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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,1,1-trichloroethane
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Accession:CHEBI:36015 term browser browse the term
Definition:A member of the class of chloroethanes carrying three chloro substituents at position 1.
Synonyms:related_synonym: 1,1,1-TCE;   1,1,1-Trichloraethan;   1,1,1-trichlorethane;   Formula=C2H3Cl3;   InChI=1S/C2H3Cl3/c1-2(3,4)5/h1H3;   InChIKey=UOCLXMDMGBRAIB-UHFFFAOYSA-N;   SMILES=CC(Cl)(Cl)Cl;   alpha-T;   alpha-trichloroethane;   methylchloroform;   methyltrichloromethane;   trichloro-1,1,1-ethane
 xref: Beilstein:1731614;   CAS:71-55-6;   Gmelin:82076;   HMDB:HMDB0041791;   KEGG:C18246
 xref_mesh: MESH:C024566
 xref: PMID:16541244;   PMID:20536226;   PMID:23102696;   PPDB:1511;   Reaxys:1731614;   Wikipedia:1\,1\,1-Trichloroethane


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1,1,1-trichloroethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO 1,1,1-trichloroethane results in increased expression of ABCA12 mRNA CTD PMID:25270620 NCBI chr 9:78,521,477...78,693,421
Ensembl chr 9:78,522,464...78,693,028
JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO 1,1,1-trichloroethane results in increased expression of ADGRD1 mRNA CTD PMID:25270620 NCBI chr12:31,134,806...31,249,594
Ensembl chr12:31,136,741...31,249,118
JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase decreases expression ISO 1,1,1-trichloroethane results in decreased expression of ALG2 mRNA CTD PMID:25270620 NCBI chr 5:63,187,466...63,192,025
Ensembl chr 5:63,187,468...63,192,025
JBrowse link
G Ckap5 cytoskeleton associated protein 5 increases expression ISO 1,1,1-trichloroethane results in increased expression of CKAP5 mRNA CTD PMID:25270620 NCBI chr 3:80,424,320...80,526,583
Ensembl chr 3:80,468,154...80,526,593
JBrowse link
G Cmtr2 cap methyltransferase 2 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of CMTR2 mRNA CTD PMID:25270620 NCBI chr19:41,426,536...41,433,367
Ensembl chr19:41,427,504...41,433,346
JBrowse link
G Cpd carboxypeptidase D decreases expression ISO 1,1,1-trichloroethane results in decreased expression of CPD mRNA CTD PMID:25270620 NCBI chr10:63,325,764...63,389,811
Ensembl chr10:63,325,199...63,389,817
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of CXCL3 mRNA CTD PMID:25270620 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases oxidation ISO CYP2E1 protein results in increased oxidation of 1,1,1-trichloroethane CTD PMID:1664256 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Entr1 endosome associated trafficking regulator 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of ENTR1 mRNA CTD PMID:25270620 NCBI chr 3:3,827,498...3,834,219
Ensembl chr 3:3,827,498...3,834,210
JBrowse link
G Etv1 ETS variant transcription factor 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of ETV1 mRNA CTD PMID:25270620 NCBI chr 6:58,467,215...58,558,640
Ensembl chr 6:58,467,254...58,558,631
JBrowse link
G Exosc10 exosome component 10 increases expression ISO 1,1,1-trichloroethane results in increased expression of EXOSC10 mRNA CTD PMID:25270620 NCBI chr 5:165,374,964...165,398,195
Ensembl chr 5:165,374,951...165,398,217
JBrowse link
G Fat3 FAT atypical cadherin 3 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of FAT3 mRNA CTD PMID:25270620 NCBI chr 8:14,417,039...15,011,596
Ensembl chr 8:14,417,584...14,880,644
JBrowse link
G Fmnl3 formin-like 3 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of FMNL3 mRNA CTD PMID:25270620 NCBI chr 7:140,981,801...141,033,318
Ensembl chr 7:140,983,342...141,001,993
JBrowse link
G Fxyd7 FXYD domain-containing ion transport regulator 7 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of FXYD7 mRNA CTD PMID:25270620 NCBI chr 1:89,474,601...89,484,069
Ensembl chr 1:89,474,601...89,483,988
JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO 1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] CTD PMID:10825391 NCBI chr10:27,310,718...27,371,802
Ensembl chr10:27,310,725...27,366,665
JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions ISO 1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] CTD PMID:10825391 NCBI chr14:38,631,192...39,112,598
Ensembl chr14:38,643,385...39,112,600
JBrowse link
G Gadl1 glutamate decarboxylase-like 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of GADL1 mRNA CTD PMID:25270620 NCBI chr 8:123,989,822...124,301,366 JBrowse link
G Gatad2a GATA zinc finger domain containing 2A increases expression ISO 1,1,1-trichloroethane results in increased expression of GATAD2A mRNA CTD PMID:25270620 NCBI chr16:21,177,793...21,267,768
Ensembl chr16:21,178,138...21,268,504
JBrowse link
G Gfra1 GDNF family receptor alpha 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of GFRA1 mRNA CTD PMID:25270620 NCBI chr 1:279,203,046...279,572,789 JBrowse link
G Gjb3 gap junction protein, beta 3 increases expression ISO 1,1,1-trichloroethane results in increased expression of GJB3 mRNA CTD PMID:25270620 NCBI chr 5:145,390,590...145,397,271
Ensembl chr 5:145,391,311...145,392,123
JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions
increases response to substance
ISO 1,1,1-trichloroethane promotes the reaction [Glycine Agents results in increased activity of GLRA1 protein mutant form]
GLRA1 protein results in increased susceptibility to 1,1,1-trichloroethane
CTD PMID:10825391 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link
G Gna12 G protein subunit alpha 12 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of GNA12 mRNA CTD PMID:25270620 NCBI chr12:15,890,202...15,971,212
Ensembl chr12:15,890,170...15,971,212
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of HMOX1 mRNA CTD PMID:25270620 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of HPRT mRNA CTD PMID:25270620 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions ISO 1,1,1-trichloroethane promotes the reaction [Serotonin results in increased activity of HTR3A protein] CTD PMID:12681521 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link
G Igsf5 immunoglobulin superfamily, member 5 increases expression ISO 1,1,1-trichloroethane results in increased expression of IGSF5 mRNA CTD PMID:25270620 NCBI chr11:36,736,580...36,779,614
Ensembl chr11:36,736,586...36,779,615
JBrowse link
G Kcnv2 potassium voltage-gated channel modifier subfamily V member 2 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of KCNV2 mRNA CTD PMID:25270620 NCBI chr 1:245,396,880...245,475,011
Ensembl chr 1:245,396,989...245,416,531
JBrowse link
G Kif24 kinesin family member 24 increases expression ISO 1,1,1-trichloroethane results in increased expression of KIF24 mRNA CTD PMID:25270620 NCBI chr 5:57,778,730...57,845,642
Ensembl chr 5:57,780,389...57,845,509
JBrowse link
G Kremen1 kringle containing transmembrane protein 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of KREMEN1 mRNA CTD PMID:25270620 NCBI chr14:85,441,209...85,503,661
Ensembl chr14:85,438,707...85,484,275
JBrowse link
G Ldb2 LIM domain binding 2 increases expression ISO 1,1,1-trichloroethane results in increased expression of LDB2 mRNA CTD PMID:25270620 NCBI chr14:70,780,605...71,112,857
Ensembl chr14:70,780,623...71,112,552
JBrowse link
G Lgmn legumain increases expression ISO 1,1,1-trichloroethane results in increased expression of LGMN mRNA CTD PMID:25270620 NCBI chr 6:126,282,246...126,308,207
Ensembl chr 6:126,282,233...126,320,726
JBrowse link
G Lrfn4 leucine rich repeat and fibronectin type III domain containing 4 increases expression ISO 1,1,1-trichloroethane results in increased expression of LRFN4 mRNA CTD PMID:25270620 NCBI chr 1:219,850,037...219,855,771
Ensembl chr 1:219,850,037...219,853,329
JBrowse link
G Mboat4 membrane bound O-acyltransferase domain containing 4 increases expression ISO 1,1,1-trichloroethane results in increased expression of MBOAT4 mRNA CTD PMID:25270620 NCBI chr16:61,782,699...61,795,414
Ensembl chr16:61,782,797...61,791,091
JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of MGME1 mRNA CTD PMID:25270620 NCBI chr 3:138,397,925...138,406,672
Ensembl chr 3:138,398,011...138,406,666
JBrowse link
G Mmp19 matrix metallopeptidase 19 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of MMP19 mRNA CTD PMID:25270620 NCBI chr 7:3,216,392...3,224,202
Ensembl chr 7:3,216,497...3,224,201
JBrowse link
G Mob3c MOB kinase activator 3C decreases expression ISO 1,1,1-trichloroethane results in decreased expression of MOB3C mRNA CTD PMID:25270620 NCBI chr 5:134,679,850...134,687,899
Ensembl chr 5:134,679,713...134,688,963
JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of MOCS2 mRNA CTD PMID:25270620 NCBI chr 2:46,980,964...46,992,886
Ensembl chr 2:46,980,976...46,992,883
JBrowse link
G Mpi mannose phosphate isomerase increases expression ISO 1,1,1-trichloroethane results in increased expression of MPI mRNA CTD PMID:25270620 NCBI chr 8:62,324,176...62,332,080
Ensembl chr 8:62,324,092...62,332,115
JBrowse link
G Mtch1 mitochondrial carrier 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of MTCH1 mRNA CTD PMID:25270620 NCBI chr20:6,937,341...6,961,165
Ensembl chr20:6,937,347...6,961,162
JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of NDFIP1 mRNA CTD PMID:25270620 NCBI chr18:31,574,759...31,625,286
Ensembl chr18:31,574,821...31,625,274
JBrowse link
G Neto1 neuropilin and tolloid like 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of NETO1 mRNA CTD PMID:25270620 NCBI chr18:83,471,342...83,585,043
Ensembl chr18:83,471,342...83,584,357
JBrowse link
G Ntaq1 N-terminal glutamine amidase 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of WDYHV1 mRNA CTD PMID:25270620 NCBI chr 7:97,957,022...97,977,158
Ensembl chr 7:97,957,003...97,994,586
JBrowse link
G Oprm1 opioid receptor, mu 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of OPRM1 mRNA CTD PMID:25270620 NCBI chr 1:43,454,803...43,704,948
Ensembl chr 1:43,454,803...43,704,948
JBrowse link
G Pirt phosphoinositide-interacting regulator of transient receptor potential channels increases expression ISO 1,1,1-trichloroethane results in increased expression of PIRT mRNA CTD PMID:25270620 NCBI chr10:53,466,870...53,485,096
Ensembl chr10:53,466,870...53,481,770
JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 increases expression ISO 1,1,1-trichloroethane results in increased expression of RAB11FIP3 mRNA CTD PMID:25270620 NCBI chr10:15,348,356...15,433,384
Ensembl chr10:15,349,888...15,381,691
JBrowse link
G Rab5c RAB5C, member RAS oncogene family increases expression ISO 1,1,1-trichloroethane results in increased expression of RAB5C mRNA CTD PMID:25270620 NCBI chr10:88,621,924...88,645,364
Ensembl chr10:88,621,925...88,645,364
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit decreases expression ISO 1,1,1-trichloroethane results in decreased expression of RELB mRNA CTD PMID:25270620 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G Rp1 RP1, axonemal microtubule associated decreases expression ISO 1,1,1-trichloroethane results in decreased expression of RP1 mRNA CTD PMID:25270620 NCBI chr 5:15,005,028...15,060,508
Ensembl chr 5:15,043,955...15,060,508
JBrowse link
G Selenot selenoprotein T increases expression ISO 1,1,1-trichloroethane results in increased expression of SELENOT mRNA CTD PMID:25270620 NCBI chr 2:148,765,412...148,781,080
Ensembl chr 2:148,765,412...148,780,276
JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of SLC29A1 mRNA CTD PMID:25270620 NCBI chr 9:17,784,468...17,799,008
Ensembl chr 9:17,784,468...17,799,005
JBrowse link
G Snx32 sorting nexin 32 increases expression ISO 1,1,1-trichloroethane results in increased expression of SNX32 mRNA CTD PMID:25270620 NCBI chr 1:220,873,782...220,890,804
Ensembl chr 1:220,874,717...220,878,059
JBrowse link
G Sri sorcin increases expression ISO 1,1,1-trichloroethane results in increased expression of SRI mRNA CTD PMID:25270620 NCBI chr 4:23,004,657...23,029,233
Ensembl chr 4:23,006,243...23,018,983
JBrowse link
G Ss18 SS18 subunit of BAF chromatin remodeling complex increases expression ISO 1,1,1-trichloroethane results in increased expression of SS18 mRNA CTD PMID:25270620 NCBI chr18:6,020,267...6,083,055
Ensembl chr18:6,020,267...6,083,033
JBrowse link
G Ss18l1 SS18L1 subunit of BAF chromatin remodeling complex increases expression ISO 1,1,1-trichloroethane results in increased expression of SS18L1 mRNA CTD PMID:25270620 NCBI chr 3:175,426,754...175,445,222
Ensembl chr 3:175,426,752...175,445,222
JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of STIP1 mRNA CTD PMID:25270620 NCBI chr 1:222,274,133...222,293,139
Ensembl chr 1:222,274,133...222,293,148
JBrowse link
G Syt2 synaptotagmin 2 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of SYT2 mRNA CTD PMID:25270620 NCBI chr13:51,569,248...51,577,824
Ensembl chr13:51,534,025...51,578,052
JBrowse link
G Tmc5 transmembrane channel-like 5 increases expression ISO 1,1,1-trichloroethane results in increased expression of TMC5 mRNA CTD PMID:25270620 NCBI chr 1:188,288,738...188,337,310
Ensembl chr 1:188,278,469...188,337,308
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO 1,1,1-trichloroethane results in increased expression of TNFRSF14 mRNA CTD PMID:25270620 NCBI chr 5:172,328,259...172,337,221
Ensembl chr 5:172,328,262...172,335,892
JBrowse link
G Triqk triple QxxK/R motif containing increases expression ISO 1,1,1-trichloroethane results in increased expression of TRIQK mRNA CTD PMID:25270620 NCBI chr 5:26,493,185...26,567,491
Ensembl chr 5:26,493,212...26,566,370
JBrowse link
G Vps16 VPS16 core subunit of CORVET and HOPS complexes increases expression ISO 1,1,1-trichloroethane results in increased expression of VPS16 mRNA CTD PMID:25270620 NCBI chr 3:122,947,887...122,969,543
Ensembl chr 3:122,947,913...122,969,541
JBrowse link
G Vps39 VPS39 subunit of HOPS complex decreases expression ISO 1,1,1-trichloroethane results in decreased expression of VPS39 mRNA CTD PMID:25270620 NCBI chr 3:112,087,213...112,125,307
Ensembl chr 3:112,087,677...112,125,318
JBrowse link
G Zkscan4 zinc finger with KRAB and SCAN domains 4 increases expression ISO 1,1,1-trichloroethane results in increased expression of ZKSCAN4 mRNA CTD PMID:25270620 NCBI chr17:45,144,000...45,154,973
Ensembl chr17:45,148,646...45,154,355
JBrowse link

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  CHEBI ontology 19801
    role 19747
      application 19395
        solvent 16478
          polar solvent 15249
            1,1,1-trichloroethane 62
Path 2
Term Annotations click to browse term
  CHEBI ontology 19801
    subatomic particle 19797
      composite particle 19797
        hadron 19797
          baryon 19797
            nucleon 19797
              atomic nucleus 19797
                atom 19797
                  main group element atom 19684
                    main group molecular entity 19684
                      s-block molecular entity 19428
                        hydrogen molecular entity 19419
                          hydrides 18460
                            organic hydride 17771
                              organic fundamental parent 17771
                                hydrocarbon 17289
                                  alkane 13700
                                    ethane 6288
                                      chloroethanes 3408
                                        1,1,1-trichloroethane 62
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