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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:1,1,1-trichloroethane
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Accession:CHEBI:36015 term browser browse the term
Definition:A member of the class of chloroethanes carrying three chloro substituents at position 1.
Synonyms:related_synonym: 1,1,1-TCE;   1,1,1-Trichloraethan;   1,1,1-trichlorethane;   Formula=C2H3Cl3;   InChI=1S/C2H3Cl3/c1-2(3,4)5/h1H3;   InChIKey=UOCLXMDMGBRAIB-UHFFFAOYSA-N;   SMILES=CC(Cl)(Cl)Cl;   alpha-T;   alpha-trichloroethane;   methylchloroform;   methyltrichloromethane;   trichloro-1,1,1-ethane
 xref: Beilstein:1731614;   CAS:71-55-6;   Gmelin:82076;   HMDB:HMDB0041791;   KEGG:C18246
 xref_mesh: MESH:C024566
 xref: PMID:16541244;   PMID:20536226;   PMID:23102696;   PPDB:1511;   Reaxys:1731614;   Wikipedia:1\,1\,1-Trichloroethane


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1,1,1-trichloroethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO 1,1,1-trichloroethane results in increased expression of ABCA12 mRNA CTD PMID:25270620 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049 		JBrowse link
G Adam1b a disintegrin and metallopeptidase domain 1b increases expression ISO 1,1,1-trichloroethane results in increased expression of ADAM1B mRNA CTD PMID:25270620 NCBI chr12:35,037,161...35,040,574
Ensembl chr12:35,037,343...35,041,082 		JBrowse link
G Adgrd1 adhesion G protein-coupled receptor D1 increases expression ISO 1,1,1-trichloroethane results in increased expression of ADGRD1 mRNA CTD PMID:25270620 NCBI chr12:27,488,908...27,603,714
Ensembl chr12:27,488,908...27,603,696 		JBrowse link
G Alg2 ALG2, alpha-1,3/1,6-mannosyltransferase decreases expression ISO 1,1,1-trichloroethane results in decreased expression of ALG2 mRNA CTD PMID:25270620 NCBI chr 5:61,768,738...61,773,297
Ensembl chr 5:61,768,740...61,773,297 		JBrowse link
G Caps calcyphosine increases expression ISO 1,1,1-trichloroethane results in increased expression of TNFRSF23 mRNA CTD PMID:25270620 NCBI chr 9:1,544,597...1,545,631
Ensembl chr 9:1,544,719...1,545,647 		JBrowse link
G Ckap5 cytoskeleton associated protein 5 increases expression ISO 1,1,1-trichloroethane results in increased expression of CKAP5 mRNA CTD PMID:25270620 NCBI chr 3:77,491,195...77,593,300
Ensembl chr 3:77,491,276...77,593,264 		JBrowse link
G Cmtr2 cap methyltransferase 2 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of CMTR2 mRNA CTD PMID:25270620 NCBI chr19:38,190,718...38,197,549
Ensembl chr19:38,190,642...38,197,804 		JBrowse link
G Cpd carboxypeptidase D decreases expression ISO 1,1,1-trichloroethane results in decreased expression of CPD mRNA CTD PMID:25270620 NCBI chr10:61,623,528...61,687,491
Ensembl chr10:61,623,526...61,687,491 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of CXCL3 mRNA CTD PMID:25270620 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases oxidation ISO CYP2E1 protein results in increased oxidation of 1,1,1-trichloroethane CTD PMID:1664256 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Entr1 endosome associated trafficking regulator 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of ENTR1 mRNA CTD PMID:25270620 NCBI chr 3:9,200,967...9,207,688
Ensembl chr 3:9,200,967...9,207,688 		JBrowse link
G Etv1 ETS variant transcription factor 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of ETV1 mRNA CTD PMID:25270620 NCBI chr 6:55,590,149...55,681,784
Ensembl chr 6:55,590,234...55,681,775 		JBrowse link
G Exosc10 exosome component 10 increases expression ISO 1,1,1-trichloroethane results in increased expression of EXOSC10 mRNA CTD PMID:25270620 NCBI chr 5:158,995,313...159,018,940
Ensembl chr 5:158,995,313...159,018,940 		JBrowse link
G Fat3 FAT atypical cadherin 3 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of FAT3 mRNA CTD PMID:25270620 NCBI chr 8:12,691,470...13,274,336
Ensembl chr 8:12,694,019...13,273,135 		JBrowse link
G Fmnl3 formin-like 3 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of FMNL3 mRNA CTD PMID:25270620 NCBI chr 7:130,454,270...130,505,626
Ensembl chr 7:130,454,275...130,505,626 		JBrowse link
G Fxyd7 FXYD domain-containing ion transport regulator 7 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of FXYD7 mRNA CTD PMID:25270620 NCBI chr 1:86,277,678...86,286,954
Ensembl chr 1:86,277,678...86,286,954 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 multiple interactions ISO 1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] CTD PMID:10825391 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabrb1 gamma-aminobutyric acid type A receptor subunit beta1 multiple interactions ISO 1,1,1-trichloroethane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]] CTD PMID:10825391 NCBI chr14:36,068,725...36,548,946
Ensembl chr14:36,080,393...36,548,948 		JBrowse link
G Gadl1 glutamate decarboxylase-like 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of GADL1 mRNA CTD PMID:25270620 NCBI chr 8:115,605,609...115,785,676
Ensembl chr 8:115,605,873...115,784,410 		JBrowse link
G Gatad2a GATA zinc finger domain containing 2A increases expression ISO 1,1,1-trichloroethane results in increased expression of GATAD2A mRNA CTD PMID:25270620 NCBI chr16:19,429,578...19,520,320
Ensembl chr16:19,429,578...19,519,587 		JBrowse link
G Gfra1 GDNF family receptor alpha 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of GFRA1 mRNA CTD PMID:25270620 NCBI chr 1:257,315,682...257,552,004
Ensembl chr 1:257,321,742...257,551,473 		JBrowse link
G Gjb3 gap junction protein, beta 3 increases expression ISO 1,1,1-trichloroethane results in increased expression of GJB3 mRNA CTD PMID:25270620 NCBI chr 5:139,649,227...139,654,970
Ensembl chr 5:139,649,195...139,654,980 		JBrowse link
G Glra1 glycine receptor, alpha 1 multiple interactions
increases response to substance		 ISO 1,1,1-trichloroethane promotes the reaction [Glycine Agents results in increased activity of GLRA1 protein mutant form]
GLRA1 protein results in increased susceptibility to 1,1,1-trichloroethane		 CTD PMID:10825391 NCBI chr10:39,625,853...39,727,897
Ensembl chr10:39,629,459...39,727,162 		JBrowse link
G Gna12 G protein subunit alpha 12 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of GNA12 mRNA CTD PMID:25270620 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of HMOX1 mRNA CTD PMID:25270620 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of HPRT1 mRNA CTD PMID:25270620 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions ISO 1,1,1-trichloroethane promotes the reaction [Serotonin results in increased activity of HTR3A protein] CTD PMID:12681521 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Igsf5 immunoglobulin superfamily, member 5 increases expression ISO 1,1,1-trichloroethane results in increased expression of IGSF5 mRNA CTD PMID:25270620 NCBI chr11:35,686,513...35,729,396
Ensembl chr11:35,686,705...35,741,129 		JBrowse link
G Kcnv2 potassium voltage-gated channel modifier subfamily V member 2 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of KCNV2 mRNA CTD PMID:25270620 NCBI chr 1:224,999,552...225,014,062
Ensembl chr 1:224,999,552...225,014,062 		JBrowse link
G Kif24 kinesin family member 24 increases expression ISO 1,1,1-trichloroethane results in increased expression of KIF24 mRNA CTD PMID:25270620 NCBI chr 5:56,561,019...56,628,040
Ensembl chr 5:56,561,154...56,628,025 		JBrowse link
G Kremen1 kringle containing transmembrane protein 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of KREMEN1 mRNA CTD PMID:25270620 NCBI chr14:80,081,870...80,147,489
Ensembl chr14:80,084,403...80,147,516 		JBrowse link
G Ldb2 LIM domain binding 2 increases expression ISO 1,1,1-trichloroethane results in increased expression of LDB2 mRNA CTD PMID:25270620 NCBI chr14:66,277,044...66,598,071
Ensembl chr14:66,277,085...66,597,778 		JBrowse link
G Lgmn legumain increases expression ISO 1,1,1-trichloroethane results in increased expression of LGMN mRNA CTD PMID:25270620 NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480 		JBrowse link
G Lrfn4 leucine rich repeat and fibronectin type III domain containing 4 increases expression ISO 1,1,1-trichloroethane results in increased expression of LRFN4 mRNA CTD PMID:25270620 NCBI chr 1:201,888,569...201,891,861
Ensembl chr 1:201,888,569...201,891,861 		JBrowse link
G Mboat4 membrane bound O-acyltransferase domain containing 4 increases expression ISO 1,1,1-trichloroethane results in increased expression of MBOAT4 mRNA CTD PMID:25270620 NCBI chr16:58,064,178...58,077,523
Ensembl chr16:58,064,840...58,073,139 		JBrowse link
G Mgme1 mitochondrial genome maintenance exonuclease 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of MGME1 mRNA CTD PMID:25270620 NCBI chr 3:131,640,770...131,649,933
Ensembl chr 3:131,640,944...131,649,932 		JBrowse link
G Mmp19 matrix metallopeptidase 19 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of MMP19 mRNA CTD PMID:25270620 NCBI chr 7:1,221,229...1,229,555
Ensembl chr 7:1,221,343...1,229,555 		JBrowse link
G Mob3c MOB kinase activator 3C decreases expression ISO 1,1,1-trichloroethane results in decreased expression of MOB3C mRNA CTD PMID:25270620 NCBI chr 5:129,306,255...129,315,264
Ensembl chr 5:129,306,569...129,315,256 		JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of MOCS2 mRNA CTD PMID:25270620 NCBI chr 2:46,504,588...46,516,327
Ensembl chr 2:46,504,588...46,516,324 		JBrowse link
G Mpi mannose phosphate isomerase increases expression ISO 1,1,1-trichloroethane results in increased expression of MPI mRNA CTD PMID:25270620 NCBI chr 8:57,947,883...57,956,205
Ensembl chr 8:57,947,893...57,956,150 		JBrowse link
G Mtch1 mitochondrial carrier 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of MTCH1 mRNA CTD PMID:25270620 NCBI chr20:7,389,942...7,413,426
Ensembl chr20:7,389,949...7,413,426 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of NDFIP1 mRNA CTD PMID:25270620 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Neto1 neuropilin and tolloid like 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of NETO1 mRNA CTD PMID:25270620 NCBI chr18:79,635,633...79,753,913
Ensembl chr18:79,635,633...79,749,030 		JBrowse link
G Ntaq1 N-terminal glutamine amidase 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of NTAQ1 mRNA CTD PMID:25270620 NCBI chr 7:89,684,318...89,704,484
Ensembl chr 7:89,684,323...89,704,474 		JBrowse link
G Oprm1 opioid receptor, mu 1 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of OPRM1 mRNA CTD PMID:25270620 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Pirt phosphoinositide-interacting regulator of transient receptor potential channels increases expression ISO 1,1,1-trichloroethane results in increased expression of PIRT mRNA CTD PMID:25270620 NCBI chr10:51,613,202...51,628,108
Ensembl chr10:51,613,126...51,632,264 		JBrowse link
G Rab11fip3 RAB11 family interacting protein 3 increases expression ISO 1,1,1-trichloroethane results in increased expression of RAB11FIP3 mRNA CTD PMID:25270620 NCBI chr10:15,002,650...15,086,382
Ensembl chr10:15,002,926...15,118,479 		JBrowse link
G Rab5c RAB5C, member RAS oncogene family increases expression ISO 1,1,1-trichloroethane results in increased expression of RAB5C mRNA CTD PMID:25270620 NCBI chr10:85,642,553...85,666,142
Ensembl chr10:85,642,809...85,666,103 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit decreases expression ISO 1,1,1-trichloroethane results in decreased expression of RELB mRNA CTD PMID:25270620 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Rp1 RP1, axonemal microtubule associated decreases expression ISO 1,1,1-trichloroethane results in decreased expression of RP1 mRNA CTD PMID:25270620 NCBI chr 5:15,121,104...15,582,363
Ensembl chr 5:15,121,133...15,579,363 		JBrowse link
G Selenot selenoprotein T increases expression ISO 1,1,1-trichloroethane results in increased expression of SELENOT mRNA CTD PMID:25270620 NCBI chr 2:142,804,387...142,821,438
Ensembl chr 2:142,804,405...142,821,427 		JBrowse link
G Slc29a1 solute carrier family 29 member 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of SLC29A1 mRNA CTD PMID:25270620 NCBI chr 9:15,399,661...15,414,203
Ensembl chr 9:15,399,612...15,414,203 		JBrowse link
G Snx32 sorting nexin 32 increases expression ISO 1,1,1-trichloroethane results in increased expression of SNX32 mRNA CTD PMID:25270620 NCBI chr 1:202,801,090...202,818,731
Ensembl chr 1:202,802,394...202,818,743 		JBrowse link
G Sri sorcin increases expression ISO 1,1,1-trichloroethane results in increased expression of SRI mRNA CTD PMID:25270620 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077 		JBrowse link
G Ss18 SS18 subunit of BAF chromatin remodeling complex increases expression ISO 1,1,1-trichloroethane results in increased expression of SS18 mRNA CTD PMID:25270620 NCBI chr18:5,773,042...5,835,696
Ensembl chr18:5,773,042...5,835,333 		JBrowse link
G Ss18l1 SS18L1 subunit of BAF chromatin remodeling complex increases expression ISO 1,1,1-trichloroethane results in increased expression of SS18L1 mRNA CTD PMID:25270620 NCBI chr 3:167,143,730...167,165,253
Ensembl chr 3:167,143,994...167,165,253 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 increases expression ISO 1,1,1-trichloroethane results in increased expression of STIP1 mRNA CTD PMID:25270620 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Syt2 synaptotagmin 2 decreases expression ISO 1,1,1-trichloroethane results in decreased expression of SYT2 mRNA CTD PMID:25270620 NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859 		JBrowse link
G Tmc5 transmembrane channel-like 5 increases expression ISO 1,1,1-trichloroethane results in increased expression of TMC5 mRNA CTD PMID:25270620 NCBI chr 1:172,914,915...172,999,478
Ensembl chr 1:172,914,457...172,999,474 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO 1,1,1-trichloroethane results in increased expression of TNFRSF14 mRNA CTD PMID:25270620 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Triqk triple QxxK/R motif containing increases expression ISO 1,1,1-trichloroethane results in increased expression of TRIQK mRNA CTD PMID:25270620 NCBI chr 5:26,391,511...26,464,422
Ensembl chr 5:26,391,552...26,464,421 		JBrowse link
G Vps16 VPS16 core subunit of CORVET and HOPS complexes increases expression ISO 1,1,1-trichloroethane results in increased expression of VPS16 mRNA CTD PMID:25270620 NCBI chr 3:117,622,534...117,644,041
Ensembl chr 3:117,622,542...117,646,441 		JBrowse link
G Vps39 VPS39 subunit of HOPS complex decreases expression ISO 1,1,1-trichloroethane results in decreased expression of VPS39 mRNA CTD PMID:25270620 NCBI chr 3:107,266,846...107,304,884
Ensembl chr 3:107,267,310...107,304,975 		JBrowse link
G Zkscan4 zinc finger with KRAB and SCAN domains 4 increases expression ISO 1,1,1-trichloroethane results in increased expression of ZKSCAN4 mRNA CTD PMID:25270620 NCBI chr17:43,104,853...43,113,101
Ensembl chr17:43,106,370...43,113,183 		JBrowse link
Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19921
    role 19893
      application 19734
        solvent 17245
          polar solvent 15716
            1,1,1-trichloroethane 64
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    main group molecular entity 19865
                      s-block molecular entity 19697
                        hydrogen molecular entity 19678
                          hydrides 19184
                            organic hydride 18719
                              organic fundamental parent 18719
                                hydrocarbon 18462
                                  halohydrocarbon 15877
                                    haloalkane 12911
                                      chloroalkane 9357
                                        chloroethanes 3440
                                          1,1,1-trichloroethane 64
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