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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:omega-6 fatty acid
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Accession:CHEBI:36009 term browser browse the term
Definition:A family of polyunsaturated fatty acids that have in common a final carbon-carbon double bond in the n-6 position, i.e., the sixth bond from the methyl end of the fatty acid.
Synonyms:related_synonym: omega-6 fatty acids
 alt_id: MESH:D043371
 xref_mesh: MESH:D043371
 xref: PMID:19035453;   PMID:19136835



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omega-6 fatty acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alg3 ALG3 alpha-1,3- mannosyltransferase decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of ALG3 mRNA CTD PMID:16823509 NCBI chr16:20,424,208...20,429,515
Ensembl chr16:20,424,124...20,430,485
JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 increases expression ISO Fatty Acids, Omega-6 results in increased expression of ATP8A1 mRNA CTD PMID:16823509 NCBI chr 5:67,775,482...68,004,822
Ensembl chr 5:67,775,483...68,004,777
JBrowse link
G Ccnd1 cyclin D1 affects response to substance ISO CCND1 gene SNP affects the susceptibility to Fatty Acids, Omega-6 CTD PMID:15845652 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Cd84 CD84 antigen decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of CD84 mRNA CTD PMID:16823509 NCBI chr 1:171,667,261...171,718,288
Ensembl chr 1:171,667,265...171,718,285
JBrowse link
G Cpb2 carboxypeptidase B2 increases expression ISO Fatty Acids, Omega-6 results in increased expression of CPB2 mRNA CTD PMID:16823509 NCBI chr14:75,479,727...75,520,995
Ensembl chr14:75,479,727...75,520,995
JBrowse link
G Dgke diacylglycerol kinase, epsilon increases expression ISO Fatty Acids, Omega-6 results in increased expression of DGKE mRNA CTD PMID:16823509 NCBI chr11:88,926,005...88,951,644
Ensembl chr11:88,926,005...88,957,676
JBrowse link
G Dusp2 dual specificity phosphatase 2 increases expression ISO Fatty Acids, Omega-6 results in increased expression of DUSP2 mRNA CTD PMID:16823509 NCBI chr 2:127,178,079...127,180,297
Ensembl chr 2:127,178,079...127,180,296
JBrowse link
G Ebi3 Epstein-Barr virus induced gene 3 decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of EBI3 mRNA CTD PMID:16823509 NCBI chr17:56,259,623...56,264,022
Ensembl chr17:56,259,640...56,264,022
JBrowse link
G Gars1 glycyl-tRNA synthetase 1 decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of GARS1 mRNA CTD PMID:16823509 NCBI chr 6:55,014,986...55,056,489
Ensembl chr 6:55,014,992...55,056,485
JBrowse link
G Gjc1 gap junction protein, gamma 1 increases expression ISO Fatty Acids, Omega-6 results in increased expression of GJC1 mRNA CTD PMID:16823509 NCBI chr11:102,690,303...102,710,512
Ensembl chr11:102,690,405...102,710,526
JBrowse link
G Hs3st1 heparan sulfate (glucosamine) 3-O-sulfotransferase 1 increases expression ISO Fatty Acids, Omega-6 results in increased expression of HS3ST1 mRNA CTD PMID:16823509 NCBI chr 5:39,771,278...39,802,791
Ensembl chr 5:39,771,278...39,912,818
JBrowse link
G Il1rap interleukin 1 receptor accessory protein increases expression ISO Fatty Acids, Omega-6 results in increased expression of IL1RAP mRNA CTD PMID:16823509 NCBI chr16:26,400,259...26,548,878
Ensembl chr16:26,400,454...26,548,867
JBrowse link
G Itgb4 integrin beta 4 increases expression ISO Fatty Acids, Omega-6 results in increased expression of ITGB4 mRNA CTD PMID:16823509 NCBI chr11:115,865,556...115,899,238
Ensembl chr11:115,865,535...115,899,238
JBrowse link
G Kif4 kinesin family member 4 increases expression ISO Fatty Acids, Omega-6 results in increased expression of KIF4A mRNA CTD PMID:16823509 NCBI chr  X:99,669,693...99,770,878
Ensembl chr  X:99,669,343...99,770,820
JBrowse link
G Msln mesothelin increases expression ISO Fatty Acids, Omega-6 results in increased expression of MSLN mRNA CTD PMID:16823509 NCBI chr17:25,967,587...25,973,352
Ensembl chr17:25,967,587...25,973,352
JBrowse link
G Nudcd3 NudC domain containing 3 increases expression ISO Fatty Acids, Omega-6 results in increased expression of NUDCD3 mRNA CTD PMID:16823509 NCBI chr11:6,055,705...6,150,190
Ensembl chr11:6,055,691...6,150,415
JBrowse link
G Pcdh1 protocadherin 1 increases expression ISO Fatty Acids, Omega-6 results in increased expression of PCDH1 mRNA CTD PMID:16823509 NCBI chr18:38,318,967...38,345,023
Ensembl chr18:38,318,967...38,345,106
JBrowse link
G Phkg1 phosphorylase kinase gamma 1 decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of PHKG1 mRNA CTD PMID:16823509 NCBI chr 5:129,892,272...129,907,953
Ensembl chr 5:129,892,262...129,927,390
JBrowse link
G Psmd11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 increases expression ISO Fatty Acids, Omega-6 results in increased expression of PSMD11 mRNA CTD PMID:16823509 NCBI chr11:80,319,441...80,364,074
Ensembl chr11:80,319,441...80,364,074
JBrowse link
G Puf60 poly-U binding splicing factor 60 decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of PUF60 mRNA CTD PMID:16823509 NCBI chr15:75,942,031...75,954,386
Ensembl chr15:75,942,031...75,952,773
JBrowse link
G Ro60 Ro60, Y RNA binding protein decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of RO60 mRNA CTD PMID:16823509 NCBI chr 1:143,626,528...143,652,794
Ensembl chr 1:143,626,528...143,652,806
JBrowse link
G Sdc4 syndecan 4 increases expression ISO Fatty Acids, Omega-6 results in increased expression of SDC4 mRNA CTD PMID:16823509 NCBI chr 2:164,266,167...164,285,512
Ensembl chr 2:164,266,167...164,285,807
JBrowse link
G Slc1a6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of SLC1A6 mRNA CTD PMID:16823509 NCBI chr10:78,615,923...78,650,659
Ensembl chr10:78,616,330...78,650,599
JBrowse link
G Slc26a4 solute carrier family 26, member 4 decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of SLC26A4 mRNA CTD PMID:16823509 NCBI chr12:31,569,813...31,610,054
Ensembl chr12:31,569,826...31,609,968
JBrowse link
G Soat1 sterol O-acyltransferase 1 increases expression ISO Fatty Acids, Omega-6 results in increased expression of SOAT1 mRNA CTD PMID:16823509 NCBI chr 1:156,255,678...156,301,898
Ensembl chr 1:156,252,095...156,301,901
JBrowse link
G Urb1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) decreases expression ISO Fatty Acids, Omega-6 results in decreased expression of URB1 mRNA CTD PMID:16823509 NCBI chr16:90,548,415...90,607,312
Ensembl chr16:90,548,415...90,607,301
JBrowse link
G Vti1b vesicle transport through interaction with t-SNAREs 1B increases expression ISO Fatty Acids, Omega-6 results in increased expression of VTI1B mRNA CTD PMID:16823509 NCBI chr12:79,202,791...79,219,428
Ensembl chr12:79,202,791...79,219,441
JBrowse link
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crp C-reactive protein, pentraxin-related affects expression ISO docosapentaenoic acid affects the expression of CRP protein CTD PMID:22113248 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Pla2g6 phospholipase A2, group VI multiple interactions ISO docosapentaenoic acid inhibits the reaction [Ethanol results in decreased expression of PLA2G6 protein] CTD PMID:25029343 NCBI chr15:79,170,428...79,212,915
Ensembl chr15:79,170,428...79,212,590
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression
multiple interactions
ISO docosapentaenoic acid results in decreased expression of PTGS2 protein
docosapentaenoic acid inhibits the reaction [Dimethoate results in increased expression of PTGS2 protein]
CTD PMID:22476691 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rxra retinoid X receptor alpha affects binding ISO docosapentaenoic acid binds to RXRA protein CTD PMID:16258897 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
1,2,3-trilinoleoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 decreases expression EXP trilinolein results in decreased expression of ABCA1 mRNA CTD PMID:18356535 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 decreases expression EXP trilinolein results in decreased expression of ABCG5 mRNA CTD PMID:18356535 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 decreases expression EXP trilinolein results in decreased expression of ABCG8 mRNA CTD PMID:18356535 NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases expression EXP trilinolein results in decreased expression of CYP27A1 mRNA CTD PMID:18356535 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase increases expression EXP trilinolein results in increased expression of HMGCR mRNA CTD PMID:18356535 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Mttp microsomal triglyceride transfer protein increases expression EXP trilinolein results in increased expression of MTTP mRNA CTD PMID:18356535 NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729
JBrowse link
G Npc1l1 NPC1 like intracellular cholesterol transporter 1 decreases expression EXP trilinolein results in decreased expression of NPC1L1 mRNA CTD PMID:18356535 NCBI chr11:6,161,011...6,180,245
Ensembl chr11:6,161,013...6,180,143
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 multiple interactions
decreases expression
EXP Clofibrate inhibits the reaction [trilinolein results in decreased expression of SCD1 mRNA] CTD PMID:8790349 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
1-hexadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fech ferrochelatase affects abundance EXP FECH protein affects the abundance of 1-palmitoyl-2-linoleoylphosphatidylcholine CTD PMID:29906468 NCBI chr18:64,589,613...64,622,169
Ensembl chr18:64,585,985...64,623,322
JBrowse link
1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipg lipase, endothelial increases hydrolysis ISO LIPG protein results in increased hydrolysis of 1-O-hexadecyl-2-arachidonyl-sn-glycero-3-phosphocholine CTD PMID:15953354 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334
JBrowse link
1-stearoyl-2-arachidonoyl-sn-glycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col1a1 collagen, type I, alpha 1 multiple interactions ISO 1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Dagla diacylglycerol lipase, alpha increases metabolic processing ISO DAGLA protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol CTD PMID:18657971 NCBI chr19:10,222,629...10,282,323
Ensembl chr19:10,222,629...10,282,241
JBrowse link
G Daglb diacylglycerol lipase, beta increases metabolic processing ISO DAGLB protein results in increased metabolism of 1-stearoyl-2-arachidonoylglycerol CTD PMID:18657971 NCBI chr 5:143,450,239...143,490,197
Ensembl chr 5:143,450,339...143,491,697
JBrowse link
G Dgke diacylglycerol kinase, epsilon increases phosphorylation ISO DGKE protein results in increased phosphorylation of 1-stearoyl-2-arachidonoylglycerol CTD PMID:17455907 NCBI chr11:88,926,005...88,951,644
Ensembl chr11:88,926,005...88,957,676
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO 1-stearoyl-2-arachidonoylglycerol results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO 1-stearoyl-2-arachidonoylglycerol inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Trpm6 transient receptor potential cation channel, subfamily M, member 6 multiple interactions ISO TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Barium]; TRPM6 protein affects the reaction [1-stearoyl-2-arachidonoylglycerol results in increased transport of Calcium] CTD PMID:11988098 NCBI chr19:18,707,566...18,869,885
Ensembl chr19:18,727,347...18,869,875
JBrowse link
1-stearoyl-2-linoleoyl-sn-glycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase, hepatic decreases abundance EXP LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol CTD PMID:24777581 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lipg lipase, endothelial decreases abundance EXP LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-linoleoyl-sn-glycerol CTD PMID:24777581 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334
JBrowse link
13-HPODE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases expression EXP
ISO
13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAT protein CTD PMID:10946007 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cav1 caveolin 1, caveolae protein increases expression ISO 13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of CAV1 mRNA CTD PMID:27257344 NCBI chr 6:17,306,387...17,341,323
Ensembl chr 6:17,306,334...17,341,451
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of CCL2 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of CCL2 protein CTD PMID:22135674 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with 2-chloro-5-nitrobenzanilide] results in increased expression of EGR1 protein; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 mRNA; [13-hydroperoxy-9,11-octadecadienoic acid co-treated with MK-886] results in increased expression of EGR1 protein CTD PMID:22135674 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO 13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARA protein CTD PMID:22135674 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma increases expression ISO 13-hydroperoxy-9,11-octadecadienoic acid results in increased expression of PPARG protein CTD PMID:22135674 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
14,15-EET term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme decreases activity ISO 14,15-epoxy-5,8,11-eicosatrienoic acid analog results in decreased activity of ACE protein CTD PMID:27428043 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790
JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions EXP 14,15-epoxy-5,8,11-eicosatrienoic acid analog promotes the reaction [REN2 protein results in increased expression of ACE2 protein] CTD PMID:27428043 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Agt angiotensinogen multiple interactions
decreases expression
increases cleavage
EXP
ISO
14,15-epoxy-5,8,11-eicosatrienoic acid analog inhibits the reaction [REN2 protein results in increased expression of AGT protein modified form]
14,15-epoxy-5,8,11-eicosatrienoic acid analog results in decreased expression of AGT protein modified form
[14,15-epoxy-5,8,11-eicosatrienoic acid analog results in increased cleavage of AGT protein modified form] which results in increased abundance of angiotensin I (1-7)
CTD PMID:27428043 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation ISO 14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of AKT1 protein CTD PMID:16286479 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases chemical synthesis ISO CYP2C8 protein results in increased chemical synthesis of 14,15-epoxy-5,8,11-eicosatrienoic acid CTD PMID:12675279 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 increases chemical synthesis
multiple interactions
ISO CYP2C9 protein results in increased chemical synthesis of 14,15-epoxy-5,8,11-eicosatrienoic acid
Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased chemical synthesis of 14,15-epoxy-5,8,11-eicosatrienoic acid]
CTD PMID:12675279 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic multiple interactions
increases abundance
EXP [Arsenites results in increased expression of and results in increased activity of EPHX2 protein] which results in decreased abundance of 14,15-epoxy-5,8,11-eicosatrienoic acid; [Mercuric Chloride results in increased expression of and results in increased activity of EPHX2 protein] which results in decreased abundance of 14,15-epoxy-5,8,11-eicosatrienoic acid
EPHX2 gene mutant form results in increased abundance of 14,15-epoxy-5,8,11-eicosatrienoic acid
CTD PMID:19896470 PMID:22680237 PMID:24472606 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression ISO 14,15-epoxy-5,8,11-eicosatrienoic acid results in increased expression of FGF2 protein CTD PMID:16286479 NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation EXP 14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of MAPK1 protein CTD PMID:19464254 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation EXP 14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of MAPK3 protein CTD PMID:19464254 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Ren2 renin 2 tandem duplication of Ren1 multiple interactions EXP 14,15-epoxy-5,8,11-eicosatrienoic acid analog inhibits the reaction [REN2 protein results in increased expression of AGT protein modified form]; 14,15-epoxy-5,8,11-eicosatrienoic acid analog inhibits the reaction [REN2 protein results in increased transport of 8-epi-prostaglandin F2alpha]; 14,15-epoxy-5,8,11-eicosatrienoic acid analog promotes the reaction [REN2 protein results in increased abundance of angiotensin I (1-7)]; 14,15-epoxy-5,8,11-eicosatrienoic acid analog promotes the reaction [REN2 protein results in increased expression of ACE2 protein]; 14,15-epoxy-5,8,11-eicosatrienoic acid analog promotes the reaction [REN2 protein results in increased transport of Nitrogen Oxides] CTD PMID:27428043
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 increases phosphorylation ISO 14,15-epoxy-5,8,11-eicosatrienoic acid results in increased phosphorylation of RPS6KB1 protein CTD PMID:16286479 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases secretion
ISO 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [TGFB1 protein results in decreased secretion of 14,15-epoxy-5,8,11-eicosatrienoic acid] CTD PMID:28694203 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
19(S)-HETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing ISO CYP2E1 protein affects the metabolism of 19-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:15205388 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases chemical synthesis ISO CYP4F3 protein alternative form results in increased chemical synthesis of 19-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:30259074 NCBI chr 8:72,742,326...72,763,512
Ensembl chr 8:72,742,326...72,763,470
JBrowse link
19-HETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects metabolic processing ISO CYP2E1 protein affects the metabolism of 19-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:15205388 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases chemical synthesis ISO CYP4F3 protein alternative form results in increased chemical synthesis of 19-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:30259074 NCBI chr 8:72,742,326...72,763,512
Ensembl chr 8:72,742,326...72,763,470
JBrowse link
2-arachidonoylglycerol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd12 abhydrolase domain containing 12 increases hydrolysis EXP ABHD12 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:18096503 NCBI chr 2:150,674,413...150,746,705
Ensembl chr 2:150,674,413...150,746,661
JBrowse link
G Abhd6 abhydrolase domain containing 6 increases hydrolysis EXP ABHD6 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:18096503 NCBI chr14:14,413,000...14,466,885
Ensembl chr14:14,413,010...14,466,871
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta increases expression
multiple interactions
ISO glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA
Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of ACTA2 mRNA]
CTD PMID:21863215 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Apoe apolipoprotein E multiple interactions EXP [[APOE protein affects the susceptibility to [Cholesterol, Dietary co-treated with Dietary Fats]] which affects the susceptibility to JZL 184] which affects the abundance of glyceryl 2-arachidonate CTD PMID:29813086 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G Arrb1 arrestin, beta 1 multiple interactions ISO glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr 7:99,184,356...99,255,979
Ensembl chr 7:99,184,673...99,255,978
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein] CTD PMID:31024316 NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654
JBrowse link
G Atf4 activating transcription factor 4 increases expression
multiple interactions
ISO glyceryl 2-arachidonate results in increased expression of ATF4 mRNA
iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of ATF4 mRNA]
CTD PMID:32357311 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP glyceryl 2-arachidonate results in increased expression of BTG2 mRNA CTD PMID:28095641 NCBI chr 1:134,002,603...134,006,893
Ensembl chr 1:134,002,908...134,006,858
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO glyceryl 2-arachidonate results in increased expression of CCL2 protein CTD PMID:15115777 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression EXP glyceryl 2-arachidonate results in increased expression of CCR1 mRNA CTD PMID:29813086 NCBI chr 9:123,762,163...123,768,729
Ensembl chr 9:123,762,161...123,768,729
JBrowse link
G Cd36 CD36 molecule increases expression EXP glyceryl 2-arachidonate results in increased expression of CD36 mRNA CTD PMID:29813086 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Ces1d carboxylesterase 1D increases hydrolysis
multiple interactions
ISO CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate
[CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid
CTD PMID:21049984 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces2h carboxylesterase 2H increases hydrolysis
multiple interactions
ISO CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate
[CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid
CTD PMID:21049984 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases expression
EXP
ISO
[CNR1 protein affects the susceptibility to Chlorpyrifos] which affects the hydrolysis of glyceryl 2-arachidonate; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
glyceryl 2-arachidonate results in increased expression of CNR1 mRNA
[GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]; glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]]
Acetaldehyde promotes the reaction [glyceryl 2-arachidonate results in increased expression of CNR1 mRNA]; Nitroglycerin affects the reaction [glyceryl 2-arachidonate affects the activity of CNR1 protein]
CTD PMID:12657697 PMID:15899896 PMID:16775503 PMID:21863215 PMID:23894352 More... NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions
affects response to substance
ISO
EXP
[GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; [SR 144528 binds to and results in increased activity of CNR2 protein] inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]; glyceryl 2-arachidonate binds to and results in increased activity of CNR2 protein; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB1 protein]; glyceryl 2-arachidonate promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; Pertussis Toxin inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]; SR 144528 inhibits the reaction [CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased transport of Calcium]]
CNR2 gene SNP affects the susceptibility to glyceryl 2-arachidonate
CTD PMID:10617657 PMID:15115777 PMID:20124950 PMID:27194477 PMID:30102254 More... NCBI chr 4:135,622,500...135,647,530
Ensembl chr 4:135,622,705...135,647,518
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 multiple interactions
increases expression
ISO
EXP
glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA] CTD PMID:23894352 NCBI chr10:80,920,163...80,934,706
Ensembl chr10:80,920,158...80,934,708
JBrowse link
G Crh corticotropin releasing hormone increases abundance EXP CRH protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:26821211 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 increases expression
multiple interactions
ISO glyceryl 2-arachidonate analog results in increased expression of CXCL8 protein; glyceryl 2-arachidonate results in increased expression of CXCL8 protein
[SR 144528 binds to and results in increased activity of CNR2 protein] inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]; CNR2 protein affects the reaction [glyceryl 2-arachidonate results in increased expression of CXCL8 protein]
CTD PMID:15115777 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO
EXP
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA]; glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 PMID:28095641 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cyp7b1 cytochrome P450, family 7, subfamily b, polypeptide 1 increases expression
multiple interactions
EXP glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7B1 mRNA]
CTD PMID:23894352 NCBI chr 3:18,126,108...18,298,054
Ensembl chr 3:18,126,114...18,297,502
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 increases expression
multiple interactions
ISO
EXP
glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP8B1 mRNA]
CTD PMID:23894352 PMID:28095641 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Dagla diacylglycerol lipase, alpha multiple interactions EXP 1-((fluoro(methyl)phosphoryl)oxy)-3-isopropoxypropan-2-yl oleate inhibits the reaction [DAGLA protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate] CTD PMID:27071101 NCBI chr19:10,222,629...10,282,323
Ensembl chr19:10,222,629...10,282,241
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased expression of DDIT3 protein]
glyceryl 2-arachidonate results in increased expression of DDIT3 mRNA; glyceryl 2-arachidonate results in increased expression of DDIT3 protein
CTD PMID:29441458 PMID:32357311 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation
multiple interactions
ISO glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein
GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein]; iodopravadoline inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of EIF2S1 protein]
CTD PMID:32357311 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Esrrg estrogen-related receptor gamma increases abundance ISO
EXP
ESRRG protein results in increased abundance of glyceryl 2-arachidonate CTD PMID:31912162 NCBI chr 1:187,340,707...187,947,082
Ensembl chr 1:187,340,988...187,947,082
JBrowse link
G Fabp1 fatty acid binding protein 1, liver affects abundance
multiple interactions
EXP FABP1 protein affects the abundance of glyceryl 2-arachidonate
FABP1 protein affects the reaction [Dronabinol results in increased abundance of glyceryl 2-arachidonate]; FABP1 protein affects the reaction [glyceryl 2-arachidonate results in increased abundance of anandamide]
CTD PMID:29414765 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fmr1 fragile X messenger ribonucleoprotein 1 multiple interactions EXP [FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate CTD PMID:20393458 NCBI chr  X:67,722,144...67,761,569
Ensembl chr  X:67,722,147...67,761,569
JBrowse link
G Fyn Fyn proto-oncogene multiple interactions ISO FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:12657697 NCBI chr10:39,245,735...39,441,377
Ensembl chr10:39,244,851...39,441,377
JBrowse link
G Grk2 G protein-coupled receptor kinase 2 multiple interactions ISO [GRK2 protein co-treated with glyceryl 2-arachidonate] affects the reaction [CNR1 protein affects the localization of ARRB2 protein]; [GRK2 protein co-treated with glyceryl 2-arachidonate] promotes the reaction [CNR2 protein affects the localization of ARRB2 protein]; GRK2 protein promotes the reaction [glyceryl 2-arachidonate affects the reaction [CNR1 protein affects the localization of ARRB1 protein]] CTD PMID:31024316 NCBI chr19:4,336,029...4,356,356
Ensembl chr19:4,336,029...4,356,250
JBrowse link
G Hcrt hypocretin increases chemical synthesis
multiple interactions
EXP HCRT protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate
1-(2-methylbenzoxazol-6-yl)-3-(1,5)naphthyridin-4-yl urea inhibits the reaction [HCRT protein modified form results in increased chemical synthesis of glyceryl 2-arachidonate]
CTD PMID:27071101 NCBI chr11:100,652,519...100,653,757
Ensembl chr11:100,651,895...100,653,757
JBrowse link
G Hspa5 heat shock protein 5 increases expression ISO glyceryl 2-arachidonate results in increased expression of HSPA5 mRNA CTD PMID:32357311 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression EXP glyceryl 2-arachidonate results in increased expression of ICAM1 mRNA CTD PMID:29813086 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
EXP glyceryl 2-arachidonate results in decreased expression of IL1B mRNA
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]
CTD PMID:16364651 PMID:30611738 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 multiple interactions ISO glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]; T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased secretion of IL2 protein]] CTD PMID:21511917 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
EXP glyceryl 2-arachidonate results in decreased expression of IL6 mRNA
glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]]
CTD PMID:16364651 PMID:30611738 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ins1 insulin I multiple interactions ISO glyceryl 2-arachidonate promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]; N-(3-methoxyphenyl)-4-chlorocinnamanilide inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [INS1 protein results in increased uptake of Deoxyglucose]] CTD PMID:31408376 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Ins2 insulin II multiple interactions ISO INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP27A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate promotes the reaction [CREB3L3 protein binds to CYP7A1 promoter]]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CREB3L3 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP27A1 mRNA]; INS protein inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Lep leptin multiple interactions EXP [Dietary Fats co-treated with LEP protein] results in increased chemical synthesis of glyceryl 2-arachidonate CTD PMID:27071101 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K1 protein] CTD PMID:12657697 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:12657697 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
EXP
ISO
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein
glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK1 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:12657697 PMID:31917333 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
EXP
ISO
CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein
glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; FYN gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]; glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in decreased phosphorylation of MAPK3 protein]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:12657697 PMID:31917333 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mgll monoglyceride lipase multiple interactions
affects abundance
increases degradation
increases abundance
increases hydrolysis
ISO
EXP
[Chlorpyrifos results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate; JZL 184 inhibits the reaction [MGLL protein results in increased hydrolysis of glyceryl 2-arachidonate]
MGLL protein affects the abundance of glyceryl 2-arachidonate
MGLL protein results in increased degradation of glyceryl 2-arachidonate
[FMR1 gene mutant form results in increased activity of MGLL] which results in increased degradation of glyceryl 2-arachidonate; [JZL 184 results in decreased activity of MGLL protein] which results in increased abundance of glyceryl 2-arachidonate; [MJN110 results in decreased activity of MGLL protein] which results in decreased hydrolysis of and results in increased abundance of glyceryl 2-arachidonate
MGLL gene mutant form results in increased abundance of glyceryl 2-arachidonate
CTD PMID:18096503 PMID:20393458 PMID:21507991 PMID:23761300 PMID:25030704 More... NCBI chr 6:88,701,397...88,805,342
Ensembl chr 6:88,701,394...88,805,342
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP glyceryl 2-arachidonate inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased activity of MPO protein]] CTD PMID:30611738 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases cleavage
ISO GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased cleavage of PARP1 protein] CTD PMID:29441458 PMID:32357311 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
affects localization
ISO [palmidrol co-treated with glyceryl 2-arachidonate] affects the localization of PPARA protein; [palmidrol co-treated with glyceryl 2-arachidonate] affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]; glyceryl 2-arachidonate affects the reaction [lipopolysaccharide, E. coli O26-B6 affects the localization of PPARA protein]
glyceryl 2-arachidonate affects the localization of PPARA protein
CTD PMID:31787870 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects binding
multiple interactions
increases expression
ISO
EXP
glyceryl 2-arachidonate metabolite binds to PPARG protein
glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in decreased expression of PPARG protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]
T 0070907 inhibits the reaction [glyceryl 2-arachidonate metabolite results in increased expression of PPARG mRNA]
CTD PMID:21511917 PMID:26209559 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [Indomethacin results in decreased expression of PTGS1] which results in increased activity of glyceryl 2-arachidonate CTD PMID:17245358 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases metabolic processing
multiple interactions
ISO
EXP
PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate
2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; CNR1 protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]; Rimonabant inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased expression of PTGS2 protein]]
glyceryl 2-arachidonate inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Calcium Ionophores] results in increased expression of PTGS2 mRNA]; Ibuprofen inhibits the reaction [PTGS2 protein results in increased metabolism of glyceryl 2-arachidonate]
CTD PMID:18297109 PMID:21511917 PMID:26209559 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions EXP 2-chloro-5-nitrobenzanilide inhibits the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]]; glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]; PPARG protein affects the reaction [glyceryl 2-arachidonate inhibits the reaction [Sulfur Dioxide results in increased phosphorylation of RELA protein]] CTD PMID:26209559 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Tnf tumor necrosis factor decreases expression
multiple interactions
EXP
ISO
glyceryl 2-arachidonate results in decreased expression of TNF mRNA
glyceryl 2-arachidonate inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]; glyceryl 2-arachidonate inhibits the reaction [amyloid beta-protein (25-35) results in increased expression of TNF protein]
glyceryl 2-arachidonate inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]
CTD PMID:12509806 PMID:16364651 PMID:30611738 PMID:30769029 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
affects response to substance
ISO glyceryl 2-arachidonate binds to and results in increased activity of TRPV1 protein
TRPV1 protein affects the susceptibility to glyceryl 2-arachidonate
CTD PMID:18550765 PMID:21949157 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
JBrowse link
G Yy1 YY1 transcription factor increases expression EXP glyceryl 2-arachidonate results in increased expression of YY1 mRNA CTD PMID:28095641 NCBI chr12:108,758,841...108,786,074
Ensembl chr12:108,758,899...108,786,074
JBrowse link
20-HETE term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions
increases expression
ISO 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 protein]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 mRNA]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 protein]
20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 mRNA; 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of ACTA2 protein
CTD PMID:36368619 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Clock clock circadian regulator affects abundance EXP CLOCK protein affects the abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:22440902 NCBI chr 5:76,357,715...76,452,675
Ensembl chr 5:76,357,715...76,452,639
JBrowse link
G Col1a1 collagen, type I, alpha 1 increases expression
multiple interactions
ISO 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 mRNA; 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 protein
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 protein]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 mRNA]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of COL1A1 protein]
CTD PMID:36368619 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B multiple interactions
increases chemical synthesis
ISO 20-hydroxy-5,8,11,14-eicosatetraenoic acid affects the reaction [CYP4A1 protein affects the susceptibility to Phenylephrine]; 20-hydroxy-5,8,11,14-eicosatetraenoic acid inhibits the reaction [DDMS inhibits the reaction [CYP4A1 protein results in increased susceptibility to Phenylephrine]]
CYP4A1 protein results in increased chemical synthesis of 20-hydroxy-5,8,11,14-eicosatetraenoic acid
CTD PMID:11124159 PMID:12388396 NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases chemical synthesis ISO CYP4F3 protein alternative form results in increased chemical synthesis of 20-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:30259074 NCBI chr 8:72,742,326...72,763,512
Ensembl chr 8:72,742,326...72,763,470
JBrowse link
G Nfatc4 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 multiple interactions
increases localization
ISO Cyclosporine inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein]; Tacrolimus inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased localization of NFATC4 protein] CTD PMID:16055480 NCBI chr14:56,062,252...56,071,400
Ensembl chr14:56,060,601...56,071,400
JBrowse link
G Pomc pro-opiomelanocortin-alpha multiple interactions
increases abundance
ISO HET0016 inhibits the reaction [POMC protein affects the abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid]
POMC protein results in increased abundance of 20-hydroxy-5,8,11,14-eicosatetraenoic acid
CTD PMID:18067589 PMID:19458537 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Smad3 SMAD family member 3 increases phosphorylation
multiple interactions
ISO 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased phosphorylation of SMAD3 protein
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased phosphorylation of SMAD3 protein]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased phosphorylation of SMAD3 protein]
CTD PMID:36368619 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Tgfb1 transforming growth factor, beta 1 increases expression
multiple interactions
ISO 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 mRNA; 20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 protein
20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 mRNA]; 20-hydroxyeicosa-5(Z),14(Z)-dienoic acid promotes the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 protein]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 mRNA]; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid inhibits the reaction [20-hydroxy-5,8,11,14-eicosatetraenoic acid results in increased expression of TGFB1 protein]
CTD PMID:36368619 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:15231852 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:15231852 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719
JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of 20-hydroxy-5,8,11,14-eicosatetraenoic acid CTD PMID:15231852 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796
JBrowse link
5,6-EET term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx2 epoxide hydrolase 2, cytoplasmic increases abundance EXP EPHX2 gene mutant form results in increased abundance of 5,6-epoxy-8,11,14-eicosatrienoic acid CTD PMID:19896470 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
8,9-EET term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 increases chemical synthesis
multiple interactions
ISO CYP2C9 protein results in increased chemical synthesis of 8,9-epoxyeicosatrienoic acid
Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased chemical synthesis of 8,9-epoxyeicosatrienoic acid]
CTD PMID:12675279 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal affects hydrolysis EXP EPHX1 protein affects the hydrolysis of 8,9-epoxyeicosatrienoic acid CTD PMID:28975360 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic increases abundance EXP EPHX2 gene mutant form results in increased abundance of 8,9-epoxyeicosatrienoic acid CTD PMID:19896470 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
9,10,13-TriHOME term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ephx3 epoxide hydrolase 3 multiple interactions EXP [EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] results in decreased abundance of [9,10,13-trihydroxy-11-octadecenoic acid binds to Ceramides]; [EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] which results in decreased chemical synthesis of 9,10,13-trihydroxy-11-octadecenoic acid CTD PMID:33334892 NCBI chr17:32,402,742...32,408,444
Ensembl chr17:32,402,744...32,408,523
JBrowse link
AACOCF3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [AGT protein results in increased abundance of Epoprostenol] CTD PMID:14613874 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions ISO
EXP
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL8 mRNA]
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA]
CTD PMID:18938131 PMID:19063610 PMID:19162293 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] CTD PMID:18938131 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 multiple interactions EXP arachidonyltrifluoromethane inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] CTD PMID:19014389 NCBI chr15:54,702,297...54,816,284
Ensembl chr15:54,702,297...54,816,288
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [NAD inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased secretion of IL1B protein]] CTD PMID:29642561 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Ins1 insulin I multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [BL 11282 promotes the reaction [Glucose results in increased secretion of INS1 protein]] CTD PMID:17922229 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Ins2 insulin II increases secretion
multiple interactions
ISO arachidonyltrifluoromethane results in increased secretion of INS protein
arachidonyltrifluoromethane inhibits the reaction [Glucose results in increased secretion of INS protein]
CTD PMID:17192482 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Lep leptin multiple interactions EXP arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of LEP mRNA] CTD PMID:19063610 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [NRG1 protein alternative form results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:15231676 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [NRG1 protein alternative form results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:15231676 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [NRG1 protein alternative form results in increased phosphorylation of and results in increased activity of MAPK1 protein]; arachidonyltrifluoromethane inhibits the reaction [NRG1 protein alternative form results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:15231676 NCBI chr 8:32,299,493...33,381,858
Ensembl chr 8:32,304,579...33,374,825
Ensembl chr 8:32,304,579...33,374,825
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) multiple interactions EXP
ISO
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of PLA2G4A protein]
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PLA2G4A mRNA]
CTD PMID:18938131 PMID:19063610 PMID:19162293 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions EXP arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARG mRNA] CTD PMID:19063610 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP
ISO
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of PTGS2 protein]; arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; arachidonyltrifluoromethane promotes the reaction [Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]] CTD PMID:18938131 PMID:19063610 PMID:19162293 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G S100a11 S100 calcium binding protein A11 multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [S100A11 mutant form results in increased susceptibility to Cisplatin]; arachidonyltrifluoromethane inhibits the reaction [S100A11 mutant form results in increased susceptibility to oxaliplatin] CTD PMID:25940438 NCBI chr 3:93,427,803...93,433,595
Ensembl chr 3:93,427,795...93,433,594
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SOCS3 mRNA] CTD PMID:19063610 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [TNF protein results in increased expression of SOD2] CTD PMID:11264281 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO arachidonyltrifluoromethane inhibits the reaction [TNF protein results in increased expression of SOD2] CTD PMID:11264281 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO
EXP
arachidonyltrifluoromethane inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]
arachidonyltrifluoromethane promotes the reaction [Nifedipine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of VEGFA mRNA]]
CTD PMID:19063610 PMID:19162293 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
all-cis-docosa-7,10,13,16-tetraenoic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rxra retinoid X receptor alpha multiple interactions ISO adrenic acid binds to and results in increased activity of RXRA protein CTD PMID:16258897 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Trp53 transformation related protein 53 multiple interactions EXP [TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of adrenic acid CTD PMID:30258081 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
anandamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP-binding cassette, sub-family B member 1A increases export ISO ABCB1 protein results in increased export of anandamide CTD PMID:30102254 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions
decreases expression
ISO 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA]; anandamide affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the expression of ABCG2 mRNA]; anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]; iodopravadoline inhibits the reaction [anandamide results in decreased expression of ABCG2 mRNA]
anandamide results in decreased expression of ABCG2 mRNA; anandamide results in decreased expression of ABCG2 protein
CTD PMID:30610963 PMID:34756920 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl multiple interactions ISO anandamide affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the expression of ACOX1 mRNA] CTD PMID:34756920 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 multiple interactions ISO anandamide affects the reaction [O,O-diethyl O-3,5,6-trichloro-2-pyridyl phosphate affects the expression of AGPAT2 mRNA] CTD PMID:34756920 NCBI chr 2:26,483,069...26,494,429
Ensembl chr 2:26,483,069...26,494,429
JBrowse link
G App amyloid beta precursor protein decreases response to substance
decreases metabolic processing
decreases abundance
ISO
EXP
anandamide results in decreased susceptibility to APP protein
APP protein results in decreased metabolism of anandamide
APP protein results in decreased abundance of anandamide
CTD PMID:22233683 PMID:26976670 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Arrb2 arrestin, beta 2 multiple interactions ISO anandamide promotes the reaction [CNR1 protein affects the localization of ARRB2 protein] CTD PMID:31024316 NCBI chr11:70,323,051...70,331,654
Ensembl chr11:70,323,461...70,331,654
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 multiple interactions
decreases activity
ISO AM 251 inhibits the reaction [anandamide results in decreased activity of BDKRB1 protein] CTD PMID:19022239 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
EXP anandamide results in increased cleavage of CASP3 protein
6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anandamide results in increased cleavage of CASP3 protein]
CTD PMID:26513129 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Cd36 CD36 molecule increases expression ISO anandamide results in increased expression of CD36 mRNA; anandamide results in increased expression of CD36 protein CTD PMID:17360047 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cga glycoprotein hormones, alpha subunit decreases expression ISO anandamide results in decreased expression of CGA mRNA CTD PMID:30610963 NCBI chr 4:34,893,779...34,907,374
Ensembl chr 4:34,893,779...34,907,370
JBrowse link
G Cnr1 cannabinoid receptor 1 affects activity
increases response to substance
decreases expression
affects binding
increases activity
multiple interactions
ISO
EXP
anandamide affects the activity of CNR1 protein
CNR1 protein results in increased susceptibility to anandamide
anandamide results in decreased expression of CNR1 protein
anandamide binds to CNR1 protein
anandamide results in increased activity of CNR1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased activity of CNR1]; anandamide promotes the reaction [CNR1 protein affects the localization of ARRB2 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Pertussis Toxin inhibits the reaction [anandamide results in increased activity of CNR1]; Rimonabant inhibits the reaction [anandamide results in increased activity of CNR1]
[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased abundance of Nitric Oxide]; [CNR1 protein affects the susceptibility to Chlorpyrifos] which affects the hydrolysis of anandamide; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Rimonabant inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]; SR 144528 inhibits the reaction [[anandamide binds to and results in increased activity of CNR1 protein] inhibits the reaction [Lipopolysaccharides results in increased transport of Nitric Oxide]]
CTD PMID:10871313 PMID:11408034 PMID:11891798 PMID:12657697 PMID:14504685 More... NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Cnr2 cannabinoid receptor 2 affects activity
affects binding
multiple interactions
ISO
EXP
anandamide affects the activity of CNR2 protein
anandamide binds to CNR2 protein
anandamide binds to and results in increased activity of CNR2 protein; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide]
CTD PMID:10617657 PMID:10688601 PMID:15453094 PMID:19147270 PMID:30102254 NCBI chr 4:135,622,500...135,647,530
Ensembl chr 4:135,622,705...135,647,518
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation
multiple interactions
ISO anandamide results in decreased phosphorylation of CREB1 protein
anandamide inhibits the reaction [Colforsin results in increased phosphorylation of CREB1 protein]; anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]; Colforsin inhibits the reaction [anandamide inhibits the reaction [CREB1 protein modified form binds to ABCG2 promoter]]
CTD PMID:30610963 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Crh corticotropin releasing hormone decreases abundance EXP CRH protein results in decreased abundance of anandamide CTD PMID:26821211 NCBI chr 3:19,747,565...19,749,560
Ensembl chr 3:19,747,565...19,749,560
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 multiple interactions
increases metabolic processing
ISO cannabichromene inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; Cannabidiol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; cannabigerol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; Cannabinol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; delta-8-tetrahydrocannabinol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide]; Dronabinol inhibits the reaction [CYP2J2 protein results in increased metabolism of anandamide] CTD PMID:29689453 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions
ISO
EXP
anandamide results in increased expression of DDIT3 mRNA; anandamide results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein]; 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid inhibits the reaction [anandamide results in increased expression of DDIT3 protein]
CTD PMID:21949157 PMID:26513129 PMID:29441458 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha multiple interactions
increases phosphorylation
EXP 4-phenylbutyric acid inhibits the reaction [anandamide results in increased phosphorylation of EIF2S1 protein] CTD PMID:26513129 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G F3 coagulation factor III increases expression
multiple interactions
ISO anandamide results in increased expression of F3 protein
anandamide promotes the reaction [IL1B protein results in increased expression of F3 protein]
CTD PMID:27556861 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Faah fatty acid amide hydrolase multiple interactions
increases response to substance
decreases metabolic processing
increases degradation
affects expression
EXP
ISO
[cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide; [nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]; [PF 3845 results in decreased activity of FAAH protein] which results in decreased metabolism of anandamide; Rimonabant inhibits the reaction [FAAH gene mutant form results in increased susceptibility to anandamide]
FAAH gene mutant form results in decreased metabolism of anandamide
FAAH protein results in increased degradation of anandamide
[Chlorpyrifos results in decreased activity of FAAH protein] which results in increased abundance of anandamide; [cyclohexyl carbamic acid 3'-carbamoylbiphenyl-3-yl ester results in decreased activity of FAAH protein] which results in increased abundance of anandamide; [Lipopolysaccharides results in decreased expression of FAAH protein] which results in increased abundance of anandamide; FAAH protein results in increased metabolism of and results in decreased activity of anandamide; Nitroglycerin promotes the reaction [FAAH protein results in increased degradation of anandamide]; Silybin inhibits the reaction [FAAH protein results in increased metabolism of and results in decreased activity of anandamide]
FAAH results in increased degradation of anandamide
anandamide affects the expression of FAAH protein
CTD PMID:11556820 PMID:16131814 PMID:16886060 PMID:19515121 PMID:20702753 More... NCBI chr 4:115,853,866...115,876,034
Ensembl chr 4:115,824,342...115,875,123
JBrowse link
G Fabp1 fatty acid binding protein 1, liver affects binding
affects abundance
multiple interactions
ISO
EXP
anandamide analog binds to FABP1 protein
FABP1 protein affects the abundance of anandamide
FABP1 protein affects the reaction [Dronabinol results in increased abundance of anandamide]; FABP1 protein affects the reaction [glyceryl 2-arachidonate results in increased abundance of anandamide]
11-hydroxy-delta(9)-tetrahydrocannabinol inhibits the reaction [anandamide analog binds to FABP1 protein]; Dronabinol inhibits the reaction [anandamide analog binds to FABP1 protein]
CTD PMID:29414765 PMID:30232874 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
ISO anandamide inhibits the reaction [Nitroglycerin results in increased expression of FOS protein]; capsazepine inhibits the reaction [anandamide results in increased expression of FOS protein]; resiniferatoxin inhibits the reaction [anandamide results in increased expression of FOS protein]
anandamide results in increased expression of FOS; anandamide results in increased expression of FOS protein
CTD PMID:9748483 PMID:15601931 PMID:19515121 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Ifng interferon gamma multiple interactions ISO anandamide affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF]; anandamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B] CTD PMID:12813001 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression EXP anandamide results in increased expression of IGF1 protein CTD PMID:17307377 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Il12b interleukin 12b multiple interactions EXP [OMDM-1 cpd co-treated with anandamide] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein]; anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL12B protein] CTD PMID:15748152 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
anandamide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL1B protein]]
anandamide inhibits the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of IL1B]; anandamide promotes the reaction [IL1B protein results in increased expression of F3 protein]
CTD PMID:12813001 PMID:15748152 PMID:27556861 PMID:30611738 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 multiple interactions EXP anandamide inhibits the reaction [Serotonin promotes the reaction [Dextran Sulfate results in increased expression of IL6 protein]] CTD PMID:30611738 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Lep leptin decreases abundance
multiple interactions
decreases activity
decreases transport
ISO
EXP
LEP protein results in decreased abundance of anandamide
Dietary Fats inhibits the reaction [LEP protein results in decreased abundance of anandamide]
LEP protein results in decreased activity of anandamide
LEP protein results in decreased transport of anandamide
CTD PMID:16154199 PMID:29967158 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein; U 0126 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K1 protein] CTD PMID:12657697 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Map2k2 mitogen-activated protein kinase kinase 2 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein; U 0126 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAP2K2 protein] CTD PMID:12657697 NCBI chr10:80,941,749...80,960,531
Ensembl chr10:80,941,749...80,969,809
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions
increases phosphorylation
EXP
ISO
anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
anandamide results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; Hydrogen Peroxide promotes the reaction [anandamide results in increased phosphorylation of MAPK1 protein]; JTE 907 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Pertussis Toxin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
CTD PMID:12657697 PMID:19477951 PMID:21179406 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; CNR1 gene mutant form inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
anandamide results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; AM 251 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; Hydrogen Peroxide promotes the reaction [anandamide results in increased phosphorylation of MAPK3 protein]; JTE 907 inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Pertussis Toxin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; wortmannin inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]; anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; rimonabant inhibits the reaction [anandamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:12657697 PMID:19477951 PMID:21179406 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mmp1b matrix metallopeptidase 1b (interstitial collagenase) increases expression ISO anandamide results in increased expression of MMP1 mRNA CTD PMID:16330497 NCBI chr 9:7,367,670...7,388,026
Ensembl chr 9:7,368,239...7,388,047
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression ISO anandamide results in increased expression of MMP3 mRNA CTD PMID:16330497 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
increases expression
ISO N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of MMP9 mRNA] CTD PMID:16330497 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; anandamide inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:11891798 PMID:15748152 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage ISO anandamide results in increased cleavage of PARP1 protein CTD PMID:29441458 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO anandamide binds to and results in increased activity of PPARA protein CTD PMID:17906680 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
increases metabolic processing
ISO
EXP
[nimesulide results in decreased expression of PTGS2] which results in increased activity of anandamide
anandamide results in increased expression of PTGS2 mRNA; anandamide results in increased expression of PTGS2 protein
PTGS2 results in increased metabolism of anandamide
[nimesulide results in decreased expression of PTGS2] promotes the reaction [FAAH affects the metabolism of anandamide]
CTD PMID:16330497 PMID:17245358 PMID:20702753 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Selp selectin, platelet multiple interactions
increases expression
ISO anandamide inhibits the reaction [thrombin receptor-activating peptide SFLLRNPNDKY results in increased expression of SELP protein]
anandamide results in increased expression of SELP protein
CTD PMID:27151562 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Synb syncytin b decreases expression ISO anandamide results in decreased expression of ERVFRD-1 mRNA CTD PMID:30610963 NCBI chr14:69,527,827...69,549,857
Ensembl chr14:69,526,793...69,531,748
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 increases expression
multiple interactions
ISO anandamide results in increased expression of TIMP1 mRNA
N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [anandamide results in increased expression of TIMP1 mRNA]
CTD PMID:16330497 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases abundance
ISO
EXP
anandamide inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of TNF protein]
anandamide inhibits the reaction [[Serotonin co-treated with Dextran Sulfate] results in increased expression of TNF protein]
TNF protein results in increased abundance of anandamide
anandamide affects the reaction [[Lipopolysaccharides co-treated with IFNG] results in increased secretion of TNF]
CTD PMID:12509806 PMID:12813001 PMID:20626112 PMID:30611738 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases response to substance
increases activity
affects response to substance
affects binding
ISO 3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; capsazepine inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; CNR1 affects the reaction [TRPV1 affects the susceptibility to anandamide]; CNR2 affects the reaction [TRPV1 affects the susceptibility to anandamide]; Egtazic Acid inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; methyl arachidonylfluorophosphonate promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; N-(2-methyl-3-hydroxyphenyl)-5,8,11,14-eicosatetraenamide inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Nitroprusside promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; Phenylmethylsulfonyl Fluoride promotes the reaction [anandamide binds to and results in increased activity of TRPV1 protein]; rimonabant inhibits the reaction [anandamide binds to and results in increased activity of TRPV1 protein]
TRPV1 protein results in increased susceptibility to anandamide
anandamide results in increased activity of TRPV1 protein
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [anandamide promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; anandamide binds to and results in increased activity of TRPV1 protein; bisindolylmaleimide inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Eicosapentaenoic Acid inhibits the reaction [anandamide results in increased activity of TRPV1 protein]; Tetradecanoylphorbol Acetate promotes the reaction [anandamide results in increased activity of TRPV1 protein]
anandamide binds to TRPV1 protein
CTD PMID:11140687 PMID:11278420 PMID:14504685 PMID:15453094 PMID:15601931 More... NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions EXP anandamide results in decreased expression of and results in decreased secretion of VEGFA protein CTD PMID:15313899 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
arachidonic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions
increases degradation
ISO Arachidonic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Arachidonic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]
Arachidonic Acid results in increased degradation of ABCA1 protein
CTD PMID:16118212 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 multiple interactions ISO Arachidonic Acid promotes the reaction [GW 4064 results in increased expression of ABCB11 mRNA] CTD PMID:15307955 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcd3 ATP-binding cassette, sub-family D member 3 decreases expression ISO Arachidonic Acid results in decreased expression of ABCD3 mRNA CTD PMID:16704987 NCBI chr 3:121,552,553...121,609,851
Ensembl chr 3:121,552,423...121,608,951
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Arachidonic Acid results in decreased expression of ABCG1 mRNA CTD PMID:16730733 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 decreases expression ISO Arachidonic Acid results in decreased expression of ADARB1 mRNA CTD PMID:16704987 NCBI chr10:77,126,561...77,254,125
Ensembl chr10:77,126,560...77,254,104
JBrowse link
G Agt angiotensinogen multiple interactions EXP Eicosapentaenoic Acid inhibits the reaction [AGT protein results in increased metabolism of and results in increased abundance of Arachidonic Acid]; Quinacrine inhibits the reaction [AGT protein results in increased metabolism of and results in increased abundance of Arachidonic Acid] CTD PMID:16257180 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO AHR affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [PLA2G4A protein results in increased secretion of Arachidonic Acid]] CTD PMID:19162293 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 increases phosphorylation
multiple interactions
EXP Arachidonic Acid results in increased phosphorylation of AKT1 protein
aristolochic acid I inhibits the reaction [Arachidonic Acid results in increased phosphorylation of AKT1 protein]
CTD PMID:19344371 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Alox12 arachidonate 12-lipoxygenase affects response to substance
increases metabolic processing
EXP
ISO
ALOX12 protein affects the susceptibility to Arachidonic Acid
ALOX12 protein results in increased metabolism of Arachidonic Acid
CTD PMID:17027136 PMID:19373248 NCBI chr11:70,132,283...70,146,206
Ensembl chr11:70,132,283...70,146,179
JBrowse link
G Alox12b arachidonate 12-lipoxygenase, 12R type multiple interactions ISO [TP53 protein results in increased expression of ALOX12B mRNA] which results in increased metabolism of Arachidonic Acid CTD PMID:30258081 NCBI chr11:69,047,898...69,060,617
Ensembl chr11:69,047,815...69,060,618
JBrowse link
G Alox15 arachidonate 15-lipoxygenase affects metabolic processing
multiple interactions
increases metabolic processing
ISO
EXP
ALOX15 protein affects the metabolism of Arachidonic Acid
[ALOX15 protein affects the metabolism of Arachidonic Acid] which affects the susceptibility to Acetylcholine; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 11,12,15-trihydroxyeicosatrienoic acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 11,14,15-trihydroxyeicosa-5,8,12-trienoic acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 15-hydroxy-11,12-epoxyeicosatrienoic acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 15-hydroxy-5,8,11,13-eicosatetraenoic acid; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of 6-Ketoprostaglandin F1 alpha; [ALOX15 protein affects the metabolism of Arachidonic Acid] which results in increased abundance of Dinoprostone; ALOX15 protein results in increased metabolism of and affects the susceptibility to Arachidonic Acid
ALOX15 protein results in increased metabolism of Arachidonic Acid
[IL4 protein co-treated with Arachidonic Acid] results in increased activity of ALOX15 protein; [IL4 protein co-treated with Arachidonic Acid] results in increased expression of ALOX15 mRNA
CTD PMID:8305483 PMID:11861792 PMID:21193584 PMID:23872364 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
increases metabolic processing
ISO [sodium arsenite co-treated with Platelet Activating Factor co-treated with Arachidonic Acid] results in increased phosphorylation of and results in increased activity of ALOX5 protein; [Sorbitol co-treated with Calcimycin co-treated with Arachidonic Acid] affects the localization of ALOX5 protein; [TP53 protein results in increased expression of ALOX5 mRNA] which results in increased metabolism of Arachidonic Acid; [zileuton results in decreased activity of ALOX5 protein] which affects the abundance of Arachidonic Acid; [zileuton results in decreased activity of ALOX5 protein] which results in decreased susceptibility to Arachidonic Acid; Arachidonic Acid inhibits the reaction [L 708714 binds to ALOX5 protein]; CJ 13610 inhibits the reaction [ALOX5 protein results in increased metabolism of Arachidonic Acid]; zileuton inhibits the reaction [ALOX5 protein results in increased metabolism of Arachidonic Acid] CTD PMID:7577949 PMID:7592874 PMID:9495842 PMID:10779545 PMID:11698504 More... NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Apoa1 apolipoprotein A-I multiple interactions
decreases expression
ISO Arachidonic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Arachidonic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]
Arachidonic Acid results in decreased expression of APOA1 mRNA
CTD PMID:7983038 PMID:16118212 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Apoc1 apolipoprotein C-I decreases expression EXP Arachidonic Acid results in decreased expression of APOC1 mRNA CTD PMID:16623957 NCBI chr 7:19,423,405...19,426,584
Ensembl chr 7:19,423,406...19,426,585
JBrowse link
G Apoe apolipoprotein E multiple interactions
decreases response to substance
ISO
EXP
APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]; Aspirin inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; dazoxiben inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; tempol inhibits the reaction [APOE gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]
Aspirin inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]; dazoxiben inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]; Indomethacin promotes the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]; tempol inhibits the reaction [APOE gene mutant form results in decreased susceptibility to Arachidonic Acid]
CTD PMID:20530721 NCBI chr 7:19,430,169...19,434,326
Ensembl chr 7:19,430,034...19,433,113
JBrowse link
G App amyloid beta precursor protein multiple interactions
increases secretion
ISO [1,1,1,2,2-pentafluoro-7-phenylheptan-3-one co-treated with Orlistat] inhibits the reaction [APP protein modified form results in increased secretion of Arachidonic Acid] CTD PMID:28721267 NCBI chr16:84,751,236...84,972,187
Ensembl chr16:84,746,573...84,970,654
JBrowse link
G Aqp3 aquaporin 3 decreases expression ISO Arachidonic Acid results in decreased expression of AQP3 mRNA CTD PMID:16704987 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression ISO Arachidonic Acid results in increased expression of ARHGDIA mRNA CTD PMID:16704987 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450
JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO Arachidonic Acid inhibits the reaction [Quercetin results in increased phosphorylation of ATF1 protein] CTD PMID:20551291 NCBI chr15:100,125,729...100,159,129
Ensembl chr15:100,125,700...100,159,125
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions
increases phosphorylation
ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in increased phosphorylation of ATF2 protein] CTD PMID:19720122 NCBI chr 2:73,646,853...73,723,094
Ensembl chr 2:73,646,853...73,722,983
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Arachidonic Acid results in increased expression of ATF3 mRNA CTD PMID:16704987 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Avp arginine vasopressin increases abundance ISO AVP protein results in increased abundance of Arachidonic Acid CTD PMID:11356622 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Arachidonic Acid co-treated with Iron] results in increased expression of BAD protein; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of BAD protein] CTD PMID:30626086 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Barx1 BarH-like homeobox 1 decreases expression EXP Arachidonic Acid results in decreased expression of BARX1 mRNA CTD PMID:16623957 NCBI chr13:48,816,512...48,819,983
Ensembl chr13:48,816,474...48,819,983
JBrowse link
G Bax BCL2-associated X protein multiple interactions
affects localization
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; [Arachidonic Acid co-treated with Iron] results in increased expression of BAX protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of BAX protein]; pyrazolanthrone inhibits the reaction [Arachidonic Acid affects the localization of BAX protein] CTD PMID:19540902 PMID:19720122 PMID:30626086 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 decreases expression
multiple interactions
ISO Arachidonic Acid results in decreased expression of BCL2 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; [Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; pyrazolanthrone inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2 protein]
CTD PMID:19540902 PMID:19620254 PMID:19720122 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression
multiple interactions
ISO Arachidonic Acid results in decreased expression of BCL2L1 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; [Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein]; pyrazolanthrone inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]; Resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of BCL2L1 protein]
CTD PMID:19540902 PMID:19620254 PMID:19720122 PMID:27916511 PMID:30626086 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bdnf brain derived neurotrophic factor decreases expression ISO Arachidonic Acid results in decreased expression of BDNF mRNA CTD PMID:16704987 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
multiple interactions
ISO Arachidonic Acid results in increased cleavage of BID protein
FADD protein promotes the reaction [Arachidonic Acid results in increased cleavage of BID protein]
CTD PMID:19720122 NCBI chr 6:120,870,080...120,894,074
Ensembl chr 6:120,868,891...120,893,814
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases degradation
ISO
EXP
Arachidonic Acid results in increased activity of CASP3 protein
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased degradation of CASP3 protein alternative form]; [Arachidonic Acid co-treated with Iron] results in decreased expression of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein; [Arachidonic Acid co-treated with Iron] results in increased expression of CASP3 protein modified form; Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein]; FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP3 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased cleavage of CASP3 protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of CASP3 protein modified form]; Resveratrol inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in decreased expression of CASP3 protein]
CTD PMID:16704987 PMID:19540902 PMID:19620254 PMID:19720122 PMID:23266427 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity
ISO FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP8 protein] CTD PMID:19720122 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 increases activity ISO Arachidonic Acid results in increased activity of CASP9 protein CTD PMID:19540902 PMID:19720122 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Cat catalase increases activity ISO Arachidonic Acid results in increased activity of CAT protein CTD PMID:7548195 PMID:16982041 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cd40 CD40 antigen multiple interactions ISO Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA] CTD PMID:15684433 NCBI chr 2:164,897,535...164,913,574
Ensembl chr 2:164,897,547...164,914,868
JBrowse link
G Ces1d carboxylesterase 1D decreases activity
multiple interactions
ISO Arachidonic Acid results in decreased activity of CES1 protein
[Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein; epigallocatechin gallate inhibits the reaction [[Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein]; gallocatechol inhibits the reaction [[Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein]
[Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein; [CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid; epigallocatechin gallate inhibits the reaction [[Arachidonic Acid co-treated with ferric chloride] results in decreased activity of CES1 protein]
CTD PMID:19761868 PMID:21049984 PMID:37353134 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO [CES2 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid CTD PMID:21049984 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO CNR2 protein affects the reaction [Arachidonic Acid results in increased expression of CXCL8 protein] CTD PMID:15115777 NCBI chr 4:135,622,500...135,647,530
Ensembl chr 4:135,622,705...135,647,518
JBrowse link
G Col18a1 collagen, type XVIII, alpha 1 decreases expression ISO Arachidonic Acid results in decreased expression of COL18A1 mRNA CTD PMID:16704987 NCBI chr10:76,888,013...77,002,351
Ensembl chr10:76,888,012...77,002,382
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression ISO Arachidonic Acid results in increased expression of CPT1A mRNA CTD PMID:15307955 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Creb1 cAMP responsive element binding protein 1 increases phosphorylation
multiple interactions
ISO Arachidonic Acid results in increased phosphorylation of CREB1 protein
Ketoconazole inhibits the reaction [Arachidonic Acid results in increased phosphorylation of CREB1 protein]
CTD PMID:17680988 NCBI chr 1:64,571,963...64,643,707
Ensembl chr 1:64,571,804...64,643,707
JBrowse link
G Csk c-src tyrosine kinase increases activity
affects localization
ISO Arachidonic Acid results in increased activity of CSK protein
Arachidonic Acid affects the localization of CSK protein
CTD PMID:18388244 NCBI chr 9:57,533,929...57,560,758
Ensembl chr 9:57,533,929...57,560,914
JBrowse link
G Ctdspl CTD small phosphatase like decreases expression ISO Arachidonic Acid results in decreased expression of CTDSPL mRNA CTD PMID:16704987 NCBI chr 9:118,751,313...118,873,187
Ensembl chr 9:118,755,521...118,873,066
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
increases secretion
EXP
ISO
Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CXCL15 mRNA]
CNR2 protein affects the reaction [Arachidonic Acid results in increased expression of CXCL8 protein]
Arachidonic Acid results in increased secretion of CXCL8 protein
CTD PMID:15115777 PMID:19063610 PMID:21457203 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cycs cytochrome c, somatic affects localization ISO Arachidonic Acid affects the localization of CYCS protein CTD PMID:19720122 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cygb cytoglobin multiple interactions ISO CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA]; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA]; CYGB protein results in decreased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid] CTD PMID:16581302 NCBI chr11:116,536,421...116,544,887
Ensembl chr11:116,536,421...116,545,139
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects metabolic processing
multiple interactions
ISO
EXP
CYP1A1 protein affects the metabolism of Arachidonic Acid
Arachidonic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]
CTD PMID:15258110 PMID:19063610 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing
decreases activity
ISO CYP1A2 protein results in increased metabolism of Arachidonic Acid
Arachidonic Acid results in decreased activity of CYP1A2 protein
CTD PMID:12675279 PMID:16978661 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects metabolic processing ISO
EXP
CYP1B1 protein affects the metabolism of Arachidonic Acid CTD PMID:15258110 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 decreases expression EXP Arachidonic Acid results in decreased expression of CYP24A1 mRNA CTD PMID:16623957 NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases metabolic processing ISO CYP2B6 protein results in increased metabolism of Arachidonic Acid CTD PMID:12675279 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c23 cytochrome P450, family 2, subfamily c, polypeptide 23 multiple interactions EXP CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein]; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein]; CYP2C23 mRNA promotes the reaction [Arachidonic Acid results in increased phosphorylation of MAPK1 protein]; CYP2C23 mRNA promotes the reaction [Arachidonic Acid results in increased phosphorylation of MAPK3 protein] CTD PMID:19464254 NCBI chr19:43,993,461...44,017,695
Ensembl chr19:43,993,461...44,017,647
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases metabolic processing ISO CYP2C8 protein results in increased metabolism of Arachidonic Acid CTD PMID:12675279 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 decreases activity
increases metabolic processing
multiple interactions
ISO Arachidonic Acid results in decreased activity of CYP2C19 protein
CYP2C19 protein results in increased metabolism of Arachidonic Acid
CYP2C19 gene SNP affects the susceptibility to [Adenosine Diphosphate co-treated with Arachidonic Acid]; CYP2C19 protein results in increased metabolism of [Arachidonic Acid co-treated with NADP]
CTD PMID:12675279 PMID:16978661 PMID:18004210 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 increases metabolic processing
decreases activity
multiple interactions
ISO CYP2C9 protein results in increased metabolism of Arachidonic Acid
Arachidonic Acid results in decreased activity of CYP2C9 protein
CYP2C9 protein results in increased metabolism of [Arachidonic Acid co-treated with NADP]; Sulfaphenazole inhibits the reaction [CYP2C9 protein results in increased metabolism of Arachidonic Acid]
CTD PMID:12675279 PMID:16978661 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases metabolic processing ISO CYP2D6 protein results in increased metabolism of Arachidonic Acid CTD PMID:12675279 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
affects hydroxylation
increases response to substance
decreases activity
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein; [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein; [Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein; [CYP2E1 protein co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Hydrogen Peroxide co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; allyl sulfide inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; allyl sulfide inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; allyl sulfide inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; Arachidonic Acid inhibits the reaction [CYP2E1 protein results in decreased expression of KLF6 mRNA alternative form]; Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]; Cadmium Chloride affects the reaction [CYP2E1 protein results in increased susceptibility to Arachidonic Acid]; CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]; CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]; CYP2E1 results in increased susceptibility to [Arachidonic Acid co-treated with Zinc Sulfate]; Ditiocarb inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; Mn(III) 5,10,15,20-tetrakis(N-methylpyridinium-2-yl)porphyrin inhibits the reaction [CYP2E1 protein results in increased susceptibility to [ferric nitrilotriacetate co-treated with Arachidonic Acid]]; pyrazolanthrone inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; SB 203580 promotes the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; Wortmannin inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Zinc Sulfate inhibits the reaction [CYP2E1 results in increased susceptibility to Arachidonic Acid]
CYP2E1 protein affects the hydroxylation of Arachidonic Acid
Arachidonic Acid results in decreased activity of CYP2E1 protein
CTD PMID:12086689 PMID:12566070 PMID:15205388 PMID:16978661 PMID:17034788 More... NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 multiple interactions ISO Arachidonic Acid inhibits the reaction [CYP2J2 protein results in decreased methylation of Astemizole] CTD PMID:12386130 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases hydroxylation
multiple interactions
ISO CYP4F3 protein alternative form results in increased hydroxylation of Arachidonic Acid
rubiarbonone C inhibits the reaction [CYP4F3 protein alternative form results in increased hydroxylation of Arachidonic Acid]
CTD PMID:30259074 NCBI chr 8:72,742,326...72,763,512
Ensembl chr 8:72,742,326...72,763,470
JBrowse link
G Dct dopachrome tautomerase decreases expression EXP Arachidonic Acid results in decreased expression of DCT mRNA CTD PMID:16623957 NCBI chr14:118,250,202...118,289,658
Ensembl chr14:118,250,202...118,289,656
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO Arachidonic Acid results in increased expression of DDIT4 mRNA CTD PMID:16704987 NCBI chr10:59,785,497...59,787,592
Ensembl chr10:59,785,491...59,787,656
JBrowse link
G Ddx24 DEAD box helicase 24 decreases expression ISO Arachidonic Acid results in decreased expression of DDX24 mRNA CTD PMID:16704987 NCBI chr12:103,374,235...103,392,106
Ensembl chr12:103,374,241...103,392,089
JBrowse link
G Des desmin increases expression ISO Arachidonic Acid results in increased expression of DES mRNA CTD PMID:19089455 NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
JBrowse link
G Dhcr7 7-dehydrocholesterol reductase decreases expression ISO Arachidonic Acid results in decreased expression of DHCR7 mRNA CTD PMID:16704987 NCBI chr 7:143,376,827...143,402,147
Ensembl chr 7:143,376,882...143,402,147
JBrowse link
G Ebp EBP cholestenol delta-isomerase decreases expression ISO Arachidonic Acid results in decreased expression of EBP mRNA CTD PMID:16704987 NCBI chr  X:8,051,568...8,059,751
Ensembl chr  X:8,051,568...8,059,751
JBrowse link
G Egfr epidermal growth factor receptor multiple interactions ISO 5,8,11,14-Eicosatetraynoic Acid inhibits the reaction [Arachidonic Acid results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15525798 NCBI chr11:16,700,153...16,868,158
Ensembl chr11:16,702,203...16,868,158
JBrowse link
G Egr1 early growth response 1 increases expression ISO
EXP
Arachidonic Acid results in increased expression of EGR1 mRNA CTD PMID:8764118 PMID:16704987 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Eif4ebp3 eukaryotic translation initiation factor 4E binding protein 3 multiple interactions ISO Arachidonic Acid promotes the reaction [Quercetin results in decreased phosphorylation of EIF4EBP3 protein] CTD PMID:20551291 NCBI chr18:36,797,113...36,799,377
Ensembl chr18:36,797,113...36,798,970
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic increases metabolic processing EXP EPHX2 protein results in increased metabolism of Arachidonic Acid CTD PMID:26165641 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Erg28 ergosterol biosynthesis 28 decreases expression ISO Arachidonic Acid results in decreased expression of ERG28 mRNA CTD PMID:16704987 NCBI chr12:85,862,221...85,871,667
Ensembl chr12:85,862,222...85,871,324
JBrowse link
G F3 coagulation factor III increases expression ISO Arachidonic Acid results in increased expression of F3 protein CTD PMID:27556861 NCBI chr 3:121,517,186...121,528,701
Ensembl chr 3:121,517,186...121,528,697
JBrowse link
G Faah fatty acid amide hydrolase increases chemical synthesis
multiple interactions
ISO FAAH protein results in increased chemical synthesis of Arachidonic Acid
Nitroglycerin promotes the reaction [FAAH protein results in increased chemical synthesis of Arachidonic Acid]
CTD PMID:19515121 NCBI chr 4:115,853,866...115,876,034
Ensembl chr 4:115,824,342...115,875,123
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP3 protein]; FADD protein promotes the reaction [Arachidonic Acid results in increased activity of CASP8 protein]; FADD protein promotes the reaction [Arachidonic Acid results in increased cleavage of BID protein] CTD PMID:19720122 NCBI chr 7:144,132,060...144,136,178
Ensembl chr 7:144,131,055...144,136,200
JBrowse link
G Fads1 fatty acid desaturase 1 multiple interactions ISO [geraniol results in decreased activity of FADS1 protein] which results in decreased chemical synthesis of Arachidonic Acid CTD PMID:16462894 NCBI chr19:10,160,245...10,174,238
Ensembl chr19:10,160,252...10,174,241
JBrowse link
G Fads2 fatty acid desaturase 2 decreases expression ISO Arachidonic Acid results in decreased expression of FADS2 mRNA CTD PMID:21457203 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110
JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]]; JUN protein affects the reaction [Arachidonic Acid results in increased expression of FAS protein]; MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]
Arachidonic Acid results in increased expression of FAS mRNA; Arachidonic Acid results in increased expression of FAS protein
CTD PMID:19720122 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions
increases expression
ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]]; JUN protein affects the reaction [Arachidonic Acid results in increased expression of FASLG protein]; MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]
Arachidonic Acid results in increased expression of FASLG mRNA; Arachidonic Acid results in increased expression of FASLG protein
CTD PMID:19720122 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase decreases expression EXP Arachidonic Acid results in decreased expression of FASN mRNA CTD PMID:19159447 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 decreases expression ISO Arachidonic Acid results in decreased expression of FGFR3 mRNA CTD PMID:16704987 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
decreases phosphorylation
ISO
EXP
[Arachidonic Acid co-treated with Quercetin co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] results in decreased expression of FOS protein; Arachidonic Acid inhibits the reaction [Quercetin results in increased expression of FOS protein]; Flurbiprofen inhibits the reaction [Arachidonic Acid results in increased expression of FOS mRNA]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of FOS mRNA]
Arachidonic Acid results in decreased phosphorylation of FOS protein
CTD PMID:8764118 PMID:10864209 PMID:15878913 PMID:16704987 PMID:19720122 More... NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosl1 fos-like antigen 1 increases expression ISO Arachidonic Acid results in increased expression of FOSL1 mRNA CTD PMID:16704987 NCBI chr19:5,497,726...5,505,966
Ensembl chr19:5,497,575...5,505,974
JBrowse link
G Gap43 growth associated protein 43 increases phosphorylation EXP Arachidonic Acid results in increased phosphorylation of GAP43 protein CTD PMID:9852580 NCBI chr16:42,068,915...42,161,014
Ensembl chr16:42,068,805...42,161,014
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
increases activity
ISO Arachidonic Acid results in increased expression of GCLC mRNA
Arachidonic Acid results in increased activity of GCLC protein
CTD PMID:16704987 PMID:17092368 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO Arachidonic Acid results in increased expression of GCLM mRNA
Arachidonic Acid metabolite results in increased expression of GCLM mRNA
CTD PMID:16704987 PMID:27012417 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Glrx glutaredoxin affects response to substance EXP GLRX protein affects the susceptibility to Arachidonic Acid CTD PMID:19373248 NCBI chr13:75,988,004...75,998,270
Ensembl chr13:75,987,987...75,998,273
JBrowse link
G Gnpda1 glucosamine-6-phosphate deaminase 1 decreases expression ISO Arachidonic Acid results in decreased expression of GNPDA1 mRNA CTD PMID:16704987 NCBI chr18:38,460,588...38,472,052
Ensembl chr18:38,460,588...38,472,056
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions EXP Drugs, Chinese Herbal inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of ALT protein]; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of ALT protein] CTD PMID:27916511 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO [Iodoacetates results in decreased activity of GPX1 protein] which affects the metabolism of Arachidonic Acid CTD PMID:11115402 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO [Iodoacetates results in decreased activity of GPX4 protein] which affects the metabolism of Arachidonic Acid; Arachidonic Acid promotes the reaction [Sodium Selenite results in increased expression of and results in increased activity of GPX4 protein] CTD PMID:11115402 PMID:14642406 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [SB 216763 results in decreased activity of GSK3B protein] results in decreased susceptibility to [Arachidonic Acid co-treated with Iron] CTD PMID:19620254 NCBI chr16:37,909,363...38,066,446
Ensembl chr16:37,909,363...38,066,446
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase decreases expression ISO Arachidonic Acid results in decreased expression of HMGCR mRNA CTD PMID:16704987 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases response to substance
ISO Arachidonic Acid results in increased expression of HMOX1 mRNA
NFE2L2 gene mutant form inhibits the reaction [Arachidonic Acid metabolite results in increased expression of HMOX1 protein]
Arachidonic Acid metabolite results in increased expression of HMOX1 mRNA; Arachidonic Acid metabolite results in increased expression of HMOX1 protein
HMOX1 protein results in decreased susceptibility to Arachidonic Acid
CTD PMID:15036350 PMID:16704987 PMID:17092368 PMID:27012417 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hs2st1 heparan sulfate 2-O-sulfotransferase 1 decreases expression ISO Arachidonic Acid results in decreased expression of HS2ST1 mRNA CTD PMID:16704987 NCBI chr 3:144,135,462...144,275,977
Ensembl chr 3:144,135,467...144,275,942
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 decreases expression EXP Arachidonic Acid results in decreased expression of HSP90AB1 mRNA CTD PMID:16623957 NCBI chr17:45,878,704...45,884,187
Ensembl chr17:45,878,701...45,884,197
JBrowse link
G Htr1a 5-hydroxytryptamine (serotonin) receptor 1A multiple interactions ISO Arachidonic Acid metabolite inhibits the reaction [HTR1A protein inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]] CTD PMID:11356925 NCBI chr13:105,580,040...105,584,630
Ensembl chr13:105,580,147...105,584,630
JBrowse link
G Id3 inhibitor of DNA binding 3 decreases expression ISO Arachidonic Acid results in decreased expression of ID3 mRNA CTD PMID:16704987 NCBI chr 4:135,871,133...135,872,703
Ensembl chr 4:135,870,808...135,873,066
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase decreases expression ISO Arachidonic Acid results in decreased expression of IDI1 mRNA CTD PMID:16704987 NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
JBrowse link
G Ift25 intraflagellar transport 25 decreases expression ISO Arachidonic Acid results in decreased expression of IFT25 mRNA CTD PMID:16704987 NCBI chr 4:107,110,889...107,137,135
Ensembl chr 4:107,110,790...107,137,135
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 decreases expression ISO Arachidonic Acid results in decreased expression of IGFBP7 mRNA CTD PMID:16704987 NCBI chr 5:77,497,092...77,555,892
Ensembl chr 5:77,497,087...77,555,888
JBrowse link
G Il12b interleukin 12b multiple interactions ISO Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of IL12B mRNA] CTD PMID:15684433 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP [IL1A protein co-treated with Arachidonic Acid] results in increased abundance of Dinoprostone CTD PMID:11351503 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Arachidonic Acid results in increased abundance of Dinoprostone] promotes the reaction [IL1B protein results in increased expression of PTGS2 protein] CTD PMID:11112151 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [IL4 protein co-treated with Arachidonic Acid] results in increased activity of ALOX15 protein; [IL4 protein co-treated with Arachidonic Acid] results in increased expression of ALOX15 mRNA CTD PMID:11861792 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 increases secretion ISO Arachidonic Acid results in increased secretion of IL6 protein CTD PMID:20436887 PMID:21457203 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ilvbl ilvB (bacterial acetolactate synthase)-like decreases expression ISO Arachidonic Acid results in decreased expression of ILVBL mRNA CTD PMID:16704987 NCBI chr10:78,410,178...78,420,336
Ensembl chr10:78,410,180...78,420,336
JBrowse link
G Ins2 insulin II increases secretion
multiple interactions
ISO Arachidonic Acid results in increased secretion of INS protein
Arachidonic Acid promotes the reaction [Glucose results in increased secretion of INS protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide promotes the reaction [Arachidonic Acid results in increased secretion of INS protein]; phenidone promotes the reaction [Arachidonic Acid results in increased secretion of INS protein]
CTD PMID:17192482 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Isl1 ISL1 transcription factor, LIM/homeodomain decreases expression ISO Arachidonic Acid results in decreased expression of ISL1 mRNA CTD PMID:16704987 NCBI chr13:116,434,806...116,446,224
Ensembl chr13:116,434,817...116,446,225
JBrowse link
G Itga2b integrin alpha 2b increases expression
multiple interactions
ISO Arachidonic Acid results in increased expression of ITGA2B protein
Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGA2B protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGA2B protein]]
CTD PMID:18413191 NCBI chr11:102,344,134...102,360,570
Ensembl chr11:102,344,123...102,360,948
JBrowse link
G Itga6 integrin alpha 6 increases expression ISO Arachidonic Acid results in increased expression of ITGA6 mRNA CTD PMID:16704987 NCBI chr 2:71,617,236...71,688,761
Ensembl chr 2:71,575,960...71,688,760
JBrowse link
G Itgb3 integrin beta 3 multiple interactions
increases expression
ISO Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein]]; Quercetin inhibits the reaction [Arachidonic Acid results in increased expression of ITGB3 protein] CTD PMID:18413191 PMID:23249183 NCBI chr11:104,498,826...104,561,302
Ensembl chr11:104,498,826...104,561,302
JBrowse link
G Jun jun proto-oncogene multiple interactions
increases expression
ISO
EXP
Arachidonic Acid results in increased expression of and results in increased phosphorylation of JUN protein; JUN protein affects the reaction [Arachidonic Acid results in increased expression of FAS protein]; JUN protein affects the reaction [Arachidonic Acid results in increased expression of FASLG protein]
Arachidonic Acid results in increased expression of JUN mRNA
CTD PMID:8764118 PMID:16704987 PMID:19720122 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Junb jun B proto-oncogene multiple interactions
increases expression
EXP 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [Arachidonic Acid analog results in increased expression of JUNB mRNA]
Arachidonic Acid results in increased expression of JUNB mRNA
CTD PMID:8764118 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Kcnk10 potassium channel, subfamily K, member 10 multiple interactions ISO Arachidonic Acid promotes the reaction [KCNK10 protein results in increased transport of Potassium] CTD PMID:16075240 NCBI chr12:98,395,691...98,544,472
Ensembl chr12:98,395,696...98,544,569
JBrowse link
G Kcnk2 potassium channel, subfamily K, member 2 multiple interactions ISO Arachidonic Acid promotes the reaction [KCNK2 protein results in increased transport of Potassium] CTD PMID:16075240 NCBI chr 1:188,940,127...189,134,951
Ensembl chr 1:188,940,127...189,134,470
JBrowse link
G Kcnk4 potassium channel, subfamily K, member 4 multiple interactions ISO Arachidonic Acid promotes the reaction [KCNK4 protein results in increased transport of Potassium] CTD PMID:10767409 PMID:16075240 NCBI chr19:6,903,030...6,912,261
Ensembl chr19:6,901,334...6,911,883
JBrowse link
G Klf5 Kruppel-like transcription factor 5 increases expression ISO Arachidonic Acid results in increased expression of KLF5 mRNA CTD PMID:16704987 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472
JBrowse link
G Klf6 Kruppel-like transcription factor 6 increases expression
multiple interactions
ISO Arachidonic Acid results in increased expression of KLF6 mRNA; Arachidonic Acid results in increased expression of KLF6 mRNA alternative form; Arachidonic Acid results in increased expression of KLF6 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; [Arachidonic Acid co-treated with Hydrogen Peroxide] results in increased expression of KLF6 protein; [Arachidonic Acid co-treated with SB 203580] results in decreased expression of KLF6 mRNA; [Arachidonic Acid co-treated with Vitamin K 3] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Hydrogen Peroxide co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; [CYP2E1 protein co-treated with Vitamin K 3 co-treated with Arachidonic Acid] results in increased expression of KLF6 protein; allyl sulfide inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; allyl sulfide inhibits the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]; allyl sulfide inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; Arachidonic Acid inhibits the reaction [CYP2E1 protein results in decreased expression of KLF6 mRNA alternative form]; Arachidonic Acid inhibits the reaction [pyrazolanthrone results in decreased expression of KLF6 mRNA]; Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA alternative form]; Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]; CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]; pyrazolanthrone inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; SB 203580 promotes the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]; Vitamin E inhibits the reaction [CYP2E1 protein promotes the reaction [Arachidonic Acid results in increased expression of KLF6 mRNA alternative form]]; Wortmannin inhibits the reaction [Arachidonic Acid promotes the reaction [CYP2E1 protein results in increased expression of KLF6 mRNA]]
CTD PMID:22486562 NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
JBrowse link
G Kng1 kininogen 1 multiple interactions ISO Arachidonic Acid inhibits the reaction [GW 4064 results in increased expression of KNG1 mRNA] CTD PMID:15307955 NCBI chr16:22,876,970...22,900,828
Ensembl chr16:22,876,615...22,900,828
JBrowse link
G Krt18 keratin 18 multiple interactions ISO [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT18 protein CTD PMID:17034788 NCBI chr15:101,936,651...101,940,461
Ensembl chr15:101,936,615...101,940,462
JBrowse link
G Krt8 keratin 8 multiple interactions ISO [[Arachidonic Acid co-treated with ferric nitrilotriacetate co-treated with Ethanol] results in increased expression of CYP2E1 protein] which results in increased expression of KRT8 protein CTD PMID:17034788 NCBI chr15:101,905,146...101,912,777
Ensembl chr15:101,905,133...101,912,917
JBrowse link
G Lamp2 lysosomal-associated membrane protein 2 decreases expression EXP Arachidonic Acid results in decreased expression of LAMP2 mRNA CTD PMID:16623957 NCBI chr  X:37,488,524...37,545,337
Ensembl chr  X:37,490,234...37,545,331
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
decreases response to substance
ISO
EXP
Aspirin inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; dazoxiben inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]; LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]; tempol inhibits the reaction [LDLR gene mutant form promotes the reaction [Arachidonic Acid results in increased abundance of 11-dehydro-thromboxane B2]]
LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid
Aspirin inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid]; dazoxiben inhibits the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid]; Indomethacin promotes the reaction [LDLR gene mutant form results in decreased susceptibility to Arachidonic Acid]
CTD PMID:20530721 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lep leptin multiple interactions EXP Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of LEP mRNA] CTD PMID:19063610 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lipc lipase, hepatic decreases abundance
multiple interactions
EXP LIPC gene mutant form results in decreased abundance of Arachidonic Acid
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Arachidonic Acid
CTD PMID:24777581 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lipg lipase, endothelial decreases abundance
multiple interactions
EXP LIPG gene mutant form results in decreased abundance of Arachidonic Acid
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Arachidonic Acid
CTD PMID:24777581 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334
JBrowse link
G Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) increases expression ISO Arachidonic Acid results in increased expression of LRAT mRNA CTD PMID:12576510 NCBI chr 3:82,799,889...82,811,281
Ensembl chr 3:82,799,886...82,811,280
JBrowse link
G Lss lanosterol synthase decreases expression ISO Arachidonic Acid results in decreased expression of LSS mRNA CTD PMID:16704987 NCBI chr10:76,367,303...76,392,973
Ensembl chr10:76,367,422...76,392,972
JBrowse link
G Ltb4r1 leukotriene B4 receptor 1 affects response to substance EXP LTB4R1 protein affects the susceptibility to Arachidonic Acid CTD PMID:10934231 NCBI chr14:56,002,154...56,005,951
Ensembl chr14:56,003,419...56,005,951
JBrowse link
G Luc7l3 LUC7-like 3 (S. cerevisiae) decreases expression ISO Arachidonic Acid results in decreased expression of LUC7L3 mRNA CTD PMID:16704987 NCBI chr11:94,181,899...94,213,196
Ensembl chr11:94,178,716...94,212,814
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) increases expression ISO Arachidonic Acid results in increased expression of MAFF mRNA CTD PMID:16704987 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 multiple interactions ISO FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]]; FOS protein affects the reaction [MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]]; MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; MAP2K1 protein inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein] CTD PMID:19720122 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
affects abundance
multiple interactions
EXP
ISO
Arachidonic Acid results in increased phosphorylation of MAPK1 protein
MAPK1 protein affects the abundance of Arachidonic Acid
[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein]; CYP2C23 mRNA promotes the reaction [Arachidonic Acid results in increased phosphorylation of MAPK1 protein]
CTD PMID:16216387 PMID:19464254 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 multiple interactions ISO MAPK14 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; MAPK14 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein]
MAPK14 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid]
CTD PMID:16120751 PMID:19540902 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
affects abundance
increases phosphorylation
EXP
ISO
[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein]; CYP2C23 mRNA promotes the reaction [Arachidonic Acid results in increased phosphorylation of MAPK3 protein]
MAPK3 protein affects the abundance of Arachidonic Acid
CTD PMID:16216387 PMID:19464254 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO MAPK8 mutant form inhibits the reaction [Arachidonic Acid affects the localization of BAX protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2 protein]; MAPK8 mutant form inhibits the reaction [Arachidonic Acid results in decreased expression of BCL2L1 protein] CTD PMID:19540902 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapt microtubule-associated protein tau increases phosphorylation
multiple interactions
ISO Arachidonic Acid results in increased phosphorylation of MAPT protein
Ro 31-8220 inhibits the reaction [Arachidonic Acid results in increased phosphorylation of MAPT protein]
CTD PMID:12605413 NCBI chr11:104,120,235...104,222,916
Ensembl chr11:104,122,216...104,222,916
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases secretion
multiple interactions
increases expression
ISO Arachidonic Acid results in increased secretion of MMP13 protein
Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP13 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP13 protein]
CTD PMID:16185265 NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
increases secretion
ISO Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP2 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP2 protein] CTD PMID:16185265 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
increases secretion
ISO Arachidonic Acid results in increased expression of MMP9 mRNA
Isotretinoin inhibits the reaction [Arachidonic Acid results in increased expression of MMP9 mRNA]; Isotretinoin inhibits the reaction [Arachidonic Acid results in increased secretion of MMP9 protein]
CTD PMID:16185265 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Mpo myeloperoxidase increases secretion
multiple interactions
increases expression
ISO
EXP
Arachidonic Acid results in increased secretion of MPO protein
5-((1,5-bis(4-methoxyphenyl)pyrazol-3-yl)dimethoxymethyl)-2-chlorobenzamide inhibits the reaction [Arachidonic Acid results in increased expression of MPO protein]
CTD PMID:3111576 PMID:9831321 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mt2 metallothionein 2 multiple interactions ISO Arachidonic Acid promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA] CTD PMID:12566070 NCBI chr 8:94,899,246...94,900,195
Ensembl chr 8:94,899,292...94,900,196
JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions ISO [Quercetin co-treated with Arachidonic Acid] results in decreased phosphorylation of MTOR protein CTD PMID:20551291 NCBI chr 4:148,533,039...148,642,142
Ensembl chr 4:148,533,068...148,642,140
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions
increases localization
ISO Adiponectin inhibits the reaction [Arachidonic Acid results in increased localization of NCF1 protein]; Arachidonic Acid affects the reaction [Zymosan analog affects the localization of NCF1 protein] CTD PMID:12101222 PMID:20832062 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions ISO Arachidonic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein] CTD PMID:12101222 NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions
increases expression
ISO NFE2L2 gene mutant form inhibits the reaction [Arachidonic Acid metabolite results in increased expression of HMOX1 protein]
Arachidonic Acid metabolite results in increased expression of NFE2L2 protein
CTD PMID:27012417 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO Arachidonic Acid results in increased cleavage of and results in increased secretion of NOX1 protein; Cholesterol, LDL affects the reaction [Adiponectin inhibits the reaction [Arachidonic Acid results in increased cleavage of NOX1 protein]] CTD PMID:20832062 NCBI chr  X:132,987,170...133,038,455
Ensembl chr  X:132,987,170...133,122,705
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO Arachidonic Acid metabolite results in increased expression of NQO1 mRNA CTD PMID:27012417 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 affects binding
multiple interactions
ISO Arachidonic Acid binds to NR1H4 protein
Arachidonic Acid inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]
CTD PMID:15307955 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Nr2f1 nuclear receptor subfamily 2, group F, member 1 decreases expression ISO Arachidonic Acid results in decreased expression of NR2F1 mRNA CTD PMID:16704987 NCBI chr13:78,337,090...78,346,954
Ensembl chr13:78,337,092...78,347,876
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 decreases expression ISO Arachidonic Acid results in decreased expression of NR4A2 mRNA CTD PMID:16704987 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions
decreases chemical synthesis
EXP [NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in decreased abundance of Arachidonic Acid analog
NR5A2 gene mutant form results in decreased chemical synthesis of Arachidonic Acid
CTD PMID:29515023 NCBI chr 1:136,770,300...136,888,186
Ensembl chr 1:136,770,309...136,888,186
JBrowse link
G Nrtn neurturin decreases expression ISO Arachidonic Acid results in decreased expression of NRTN mRNA CTD PMID:16704987 NCBI chr17:57,058,323...57,064,548
Ensembl chr17:57,058,325...57,064,530
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases cleavage
ISO
EXP
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [Arachidonic Acid results in increased cleavage of PARP1 protein]; [Arachidonic Acid co-treated with Iron] results in increased expression of PARP1 protein modified form; Plant Extracts inhibits the reaction [[Arachidonic Acid co-treated with Iron] results in increased expression of PARP1 protein modified form] CTD PMID:10403056 PMID:19540902 PMID:21132278 PMID:30626086 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pde4dip phosphodiesterase 4D interacting protein (myomegalin) decreases expression ISO Arachidonic Acid results in decreased expression of PDE4DIP mRNA CTD PMID:16704987 NCBI chr 3:97,597,144...97,796,023
Ensembl chr 3:97,597,140...97,796,023
JBrowse link
G Pdss2 prenyl (solanesyl) diphosphate synthase, subunit 2 decreases expression ISO Arachidonic Acid results in decreased expression of PDSS2 mRNA CTD PMID:16704987 NCBI chr10:43,095,396...43,340,878
Ensembl chr10:43,097,482...43,340,878
JBrowse link
G Phlda1 pleckstrin homology like domain, family A, member 1 increases expression ISO Arachidonic Acid results in increased expression of PHLDA1 mRNA CTD PMID:16704987 NCBI chr10:111,342,147...111,344,510
Ensembl chr10:111,342,147...111,344,506
JBrowse link
G Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) multiple interactions
increases expression
ISO AHR affects the reaction [Tetrachlorodibenzodioxin promotes the reaction [PLA2G4A protein results in increased secretion of Arachidonic Acid]]; Dinoprostone promotes the reaction [Arachidonic Acid results in increased expression of PLA2G4A mRNA]; Flurbiprofen inhibits the reaction [Arachidonic Acid results in increased expression of PLA2G4A mRNA]
PLA2G4A protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid]
Arachidonic Acid results in increased expression of PLA2G4A mRNA; Arachidonic Acid results in increased expression of PLA2G4A protein
CTD PMID:15878913 PMID:16120751 PMID:19162293 NCBI chr 1:149,705,369...149,837,041
Ensembl chr 1:149,705,369...149,837,041
JBrowse link
G Pla2g5 phospholipase A2, group V multiple interactions ISO PLA2G5 protein promotes the reaction [N-Formylmethionine Leucyl-Phenylalanine results in increased abundance of Arachidonic Acid] CTD PMID:9495842 NCBI chr 4:138,526,558...138,590,784
Ensembl chr 4:138,526,555...138,590,793
JBrowse link
G Pla2g6 phospholipase A2, group VI multiple interactions ISO PLA2G6 protein promotes the reaction [2,2',4,6-tetrachlorobiphenyl results in increased secretion of Arachidonic Acid] CTD PMID:16120751 NCBI chr15:79,170,428...79,212,915
Ensembl chr15:79,170,428...79,212,590
JBrowse link
G Plaa phospholipase A2, activating protein multiple interactions EXP PLAA protein promotes the reaction [Lipopolysaccharides results in increased abundance of Arachidonic Acid] CTD PMID:11094054 NCBI chr 4:94,453,371...94,491,410
Ensembl chr 4:94,455,751...94,491,481
JBrowse link
G Plin2 perilipin 2 increases expression EXP
ISO
Arachidonic Acid results in increased expression of PLIN2 mRNA
Arachidonic Acid results in increased expression of PLIN2 mRNA; Arachidonic Acid results in increased expression of PLIN2 protein
CTD PMID:16489205 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Arachidonic Acid results in increased expression of PMAIP1 mRNA CTD PMID:16704987 NCBI chr18:66,591,675...66,598,629
Ensembl chr18:66,591,604...66,598,636
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
ISO Arachidonic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; Arachidonic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]
Arachidonic Acid results in decreased activity of PON1 protein
CTD PMID:15375178 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression
multiple interactions
ISO Arachidonic Acid results in increased expression of PPARA mRNA; Arachidonic Acid results in increased expression of PPARA protein
Arachidonic Acid binds to and results in increased activity of PPARA protein
CTD PMID:10403814 PMID:11172467 PMID:15491415 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppard peroxisome proliferator activator receptor delta increases expression ISO Arachidonic Acid results in increased expression of PPARD mRNA CTD PMID:11172467 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma decreases expression
increases expression
multiple interactions
ISO
EXP
Arachidonic Acid results in decreased expression of PPARG mRNA; Arachidonic Acid results in decreased expression of PPARG protein
Arachidonic Acid results in increased expression of PPARG protein
Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in decreased expression of PPARG mRNA]
CTD PMID:11172467 PMID:12604186 PMID:19063610 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha decreases expression EXP Arachidonic Acid results in decreased expression of PPP1CA mRNA CTD PMID:16623957 NCBI chr19:4,242,173...4,245,418
Ensembl chr19:4,242,064...4,245,419
JBrowse link
G Prpf4 pre-mRNA processing factor 4 decreases expression ISO Arachidonic Acid results in decreased expression of PRPF4 mRNA CTD PMID:16704987 NCBI chr 4:62,327,002...62,345,227
Ensembl chr 4:62,327,034...62,345,227
JBrowse link
G Psat1 phosphoserine aminotransferase 1 increases expression ISO Arachidonic Acid results in increased expression of PSAT1 mRNA CTD PMID:16704987 NCBI chr19:15,882,487...15,902,423
Ensembl chr19:15,882,042...15,924,701
JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions ISO [Docosahexaenoic Acids co-treated with Arachidonic Acid] affects the expression of PTAFR mRNA; Arachidonic Acid inhibits the reaction [1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of PTAFR mRNA] CTD PMID:17515866 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 increases activity
increases response to substance
increases metabolic processing
multiple interactions
ISO
EXP
Arachidonic Acid results in increased activity of PTGS1 protein
PTGS1 results in increased susceptibility to Arachidonic Acid
PTGS1 protein alternative form results in increased metabolism of Arachidonic Acid; PTGS1 protein results in increased metabolism of Arachidonic Acid
[[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine; [Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine; [PTGS1 protein results in increased metabolism of Arachidonic Acid] which results in increased chemical synthesis of 12-hydroxy-5,8,10-heptadecatrienoic acid; [PTGS1 protein results in increased metabolism of Arachidonic Acid] which results in increased chemical synthesis of Thromboxane B2; arzanol inhibits the reaction [[PTGS1 protein results in increased metabolism of Arachidonic Acid] which results in increased chemical synthesis of 12-hydroxy-5,8,10-heptadecatrienoic acid]; arzanol inhibits the reaction [[PTGS1 protein results in increased metabolism of Arachidonic Acid] which results in increased chemical synthesis of Thromboxane B2]; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; DuP 697 inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; Resveratrol inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; SC 560 inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]; valerylsalicylate inhibits the reaction [Arachidonic Acid results in increased activity of PTGS1 protein]
CTD PMID:15863457 PMID:16141368 PMID:19751497 PMID:20933508 PMID:21163909 NCBI chr 2:36,106,758...36,142,287
Ensembl chr 2:36,120,438...36,142,284
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression
increases metabolic processing
increases response to substance
increases activity
ISO
EXP
[[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [Arachidonic Acid results in increased abundance of Dinoprostone] promotes the reaction [IL1B protein results in increased expression of PTGS2 protein]; [Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to 3,4-Methylenedioxyamphetamine; [Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine; [lenabasum results in increased expression of PTGS2 mRNA] which results in increased secretion of Arachidonic Acid; [PTGS2 co-treated with Arachidonic Acid] results in increased expression of VEGFA; Arachidonic Acid inhibits the reaction [5,5-dimethyl-3-(3-fluorophenyl)-4-(4-methylsulfonyl)phenyl-2(5H)-furanone binds to and results in decreased activity of PTGS2 protein]; Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [Arachidonic Acid results in increased activity of PTGS2 protein]; Dinoprostone promotes the reaction [Arachidonic Acid results in increased expression of PTGS2 mRNA]; Flurbiprofen inhibits the reaction [Arachidonic Acid results in increased expression of PTGS2 mRNA]; Ibuprofen inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]; nimesulide inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]
Arachidonic Acid results in increased expression of PTGS2 protein
PTGS2 results in increased susceptibility to Arachidonic Acid
12-HPETE inhibits the reaction [Sodium Salicylate inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]]; 2-methoxybenzoic acid inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]; [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased metabolism of Arachidonic Acid; [nimesulide results in decreased expression of PTGS2] which results in increased abundance of Arachidonic Acid; [PTGS2 protein results in increased abundance of prostaglandin G2] inhibits the reaction [Sodium Salicylate inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]]; Arachidonic Acid affects the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]; Benzoic Acid inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]; Eugenol inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased metabolism of Arachidonic Acid]; Sodium Salicylate inhibits the reaction [PTGS2 protein results in increased metabolism of Arachidonic Acid]
Arachidonic Acid results in increased expression of PTGS2 mRNA; Arachidonic Acid results in increased expression of PTGS2 protein
CTD PMID:9013627 PMID:9146894 PMID:11112151 PMID:12538810 PMID:12757841 More... NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptp4a1 protein tyrosine phosphatase 4a1 increases expression ISO Arachidonic Acid results in increased expression of PTP4A1 mRNA CTD PMID:16704987 NCBI chr 1:30,979,384...30,988,838
Ensembl chr 1:30,979,383...30,988,390
Ensembl chr 1:30,979,383...30,988,390
JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 increases expression ISO Arachidonic Acid results in increased expression of RAPGEF2 mRNA CTD PMID:16704987 NCBI chr 3:78,969,818...79,194,681
Ensembl chr 3:78,969,823...79,193,824
JBrowse link
G Retn resistin decreases expression ISO Arachidonic Acid results in decreased expression of RETN mRNA CTD PMID:15949695 NCBI chr 8:3,705,770...3,709,818
Ensembl chr 8:3,705,770...3,710,110
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 multiple interactions ISO Arachidonic Acid promotes the reaction [Quercetin results in decreased phosphorylation of RPS6KB1 protein] CTD PMID:20551291 NCBI chr11:86,389,695...86,435,711
Ensembl chr11:86,389,697...86,435,631
JBrowse link
G Rxra retinoid X receptor alpha affects binding ISO Arachidonic Acid binds to RXRA protein CTD PMID:16258897 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression ISO Arachidonic Acid results in increased expression of SCD mRNA CTD PMID:21457203 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
JBrowse link
G Selp selectin, platelet increases expression
multiple interactions
ISO Arachidonic Acid results in increased expression of SELP protein
Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]; Glucose inhibits the reaction [Aspirin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]]; Quercetin inhibits the reaction [Arachidonic Acid results in increased expression of SELP protein]
CTD PMID:17543677 PMID:18413191 PMID:23249183 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Serpinb2 serine (or cysteine) peptidase inhibitor, clade B, member 2 increases expression ISO Arachidonic Acid results in increased expression of SERPINB2 mRNA CTD PMID:18388244 NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208
JBrowse link
G Skp2 S-phase kinase-associated protein 2 decreases expression ISO Arachidonic Acid results in decreased expression of SKP2 mRNA CTD PMID:16704987 NCBI chr15:9,112,070...9,155,512
Ensembl chr15:9,112,073...9,155,512
JBrowse link
G Slc4a2 solute carrier family 4 (anion exchanger), member 2 increases expression EXP Arachidonic Acid results in increased expression of SLC4A2 mRNA CTD PMID:16623957 NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 increases expression ISO Arachidonic Acid results in increased expression of SLC7A11 mRNA CTD PMID:16704987 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Snai2 snail family zinc finger 2 increases expression ISO Arachidonic Acid results in increased expression of SNAI2 mRNA CTD PMID:16704987 NCBI chr16:14,523,716...14,527,259
Ensembl chr16:14,523,716...14,527,249
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP Arachidonic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SOCS3 mRNA] CTD PMID:19063610 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sod1 superoxide dismutase 1, soluble decreases activity
increases activity
multiple interactions
ISO Arachidonic Acid results in decreased activity of SOD1 protein
Arachidonic Acid results in increased activity of SOD1 protein
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Arachidonic Acid results in decreased activity of SOD1 protein]; Indomethacin inhibits the reaction [Arachidonic Acid results in decreased activity of SOD1 protein]
CTD PMID:16982041 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions
increases activity
increases expression
ISO [Arachidonic Acid results in increased abundance of Reactive Oxygen Species] which results in increased expression of SOD2; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Arachidonic Acid results in increased expression of and results in increased activity of SOD2 protein; calphostin C inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; calphostin C inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Dactinomycin inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Indomethacin inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Indomethacin inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Masoprocol inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Masoprocol inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Phenols inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; pyrrolidine dithiocarbamic acid inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]
Arachidonic Acid results in increased activity of SOD2 protein
2,3,5-trimethyl-6-(12-hydroxy-5,10-dodecadiynyl)-1,4-benzoquinone inhibits the reaction [Arachidonic Acid results in increased activity of SOD2 protein]; Indomethacin inhibits the reaction [Arachidonic Acid results in increased activity of SOD2 protein]
CTD PMID:12031898 PMID:16982041 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Sox9 SRY (sex determining region Y)-box 9 decreases expression ISO Arachidonic Acid results in decreased expression of SOX9 mRNA CTD PMID:16704987 NCBI chr11:112,673,036...112,678,583
Ensembl chr11:112,673,050...112,678,586
JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein decreases expression ISO Arachidonic Acid results in decreased expression of SPARC mRNA CTD PMID:16704987 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009
JBrowse link
G Spast spastin decreases expression ISO Arachidonic Acid results in decreased expression of SPAST mRNA CTD PMID:16704987 NCBI chr17:74,643,805...74,698,110
Ensembl chr17:74,645,982...74,698,110
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Arachidonic Acid results in increased expression of SQSTM1 mRNA CTD PMID:16704987 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 decreases expression ISO Arachidonic Acid results in decreased expression of SRGAP2 mRNA CTD PMID:16704987 NCBI chr 1:131,212,989...131,455,269
Ensembl chr 1:131,212,989...131,455,090
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) increases expression ISO Arachidonic Acid metabolite results in increased expression of SRXN1 mRNA CTD PMID:27012417 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
G Ssr2 signal sequence receptor, beta decreases expression EXP Arachidonic Acid results in decreased expression of SSR2 mRNA CTD PMID:16623957 NCBI chr 3:88,486,915...88,495,727
Ensembl chr 3:88,483,183...88,495,726
JBrowse link
G Star steroidogenic acute regulatory protein increases expression
multiple interactions
ISO Arachidonic Acid results in increased expression of STAR protein
Arachidonic Acid inhibits the reaction [Dimethoate results in decreased expression of STAR protein]
CTD PMID:22476691 NCBI chr 8:26,298,502...26,306,010
Ensembl chr 8:26,296,583...26,306,010
JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO Arachidonic Acid results in increased expression of STC2 mRNA CTD PMID:16704987 NCBI chr11:31,309,441...31,320,061
Ensembl chr11:31,307,307...31,320,074
JBrowse link
G Stk11 serine/threonine kinase 11 multiple interactions ISO STK11 protein affects the reaction [resveratrol results in decreased susceptibility to [Arachidonic Acid co-treated with Iron]] CTD PMID:19620254 NCBI chr10:79,951,602...79,966,513
Ensembl chr10:79,951,637...79,966,516
JBrowse link
G Tfeb transcription factor EB decreases expression EXP Arachidonic Acid results in decreased expression of TFEB mRNA CTD PMID:16623957 NCBI chr17:48,047,962...48,103,341
Ensembl chr17:48,047,955...48,103,344
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TGFB1 mRNA] CTD PMID:16581302 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Thrsp thyroid hormone responsive decreases expression
multiple interactions
EXP Arachidonic Acid results in decreased expression of THRSP mRNA
Flurbiprofen inhibits the reaction [Arachidonic Acid results in decreased expression of THRSP mRNA]
CTD PMID:10357836 NCBI chr 7:97,062,140...97,066,757
Ensembl chr 7:97,062,145...97,066,937
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions ISO [ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA; CYGB protein inhibits the reaction [[ferric nitrilotriacetate co-treated with Arachidonic Acid] results in increased expression of TIMP1 mRNA] CTD PMID:16581302 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO [Docosahexaenoic Acids co-treated with Arachidonic Acid] affects the expression of TLR4 mRNA; Arachidonic Acid inhibits the reaction [1-O-hexadecyl-2-N-methylcarbamylphosphatidylcholine results in increased expression of TLR4 mRNA] CTD PMID:17515866 NCBI chr 4:66,745,788...66,765,338
Ensembl chr 4:66,745,821...66,848,521
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases abundance
increases secretion
ISO
EXP
Arachidonic Acid inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased secretion of Arachidonic Acid]
TNF protein results in increased abundance of Arachidonic Acid
Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]; TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]]
CTD PMID:1515551 PMID:10588948 PMID:15684433 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a increases expression ISO Arachidonic Acid results in increased expression of TNFRSF12A mRNA CTD PMID:16704987 NCBI chr17:23,894,419...23,896,423
Ensembl chr17:23,894,419...23,896,442
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a multiple interactions EXP TNFRSF1A protein affects the reaction [Butylated Hydroxyanisole inhibits the reaction [TNF protein results in increased abundance of Arachidonic Acid]] CTD PMID:10588948 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tns3 tensin 3 decreases expression ISO Arachidonic Acid results in decreased expression of TNS3 mRNA CTD PMID:16704987 NCBI chr11:8,381,652...8,614,758
Ensembl chr11:8,381,652...8,614,681
JBrowse link
G Top2a topoisomerase (DNA) II alpha decreases expression ISO Arachidonic Acid results in decreased expression of TOP2A mRNA CTD PMID:16704987 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
JBrowse link
G Trp53 transformation related protein 53 multiple interactions EXP
ISO
[TP53 protein mutant form results in increased susceptibility to Niclosamide] which results in increased abundance of Arachidonic Acid
[TP53 protein results in increased expression of ALOX12B mRNA] which results in increased metabolism of Arachidonic Acid; [TP53 protein results in increased expression of ALOX5 mRNA] which results in increased metabolism of Arachidonic Acid
CTD PMID:30258081 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Trpa1 transient receptor potential cation channel, subfamily A, member 1 increases activity
multiple interactions
EXP Arachidonic Acid results in increased activity of TRPA1 protein
Ruthenium Red inhibits the reaction [Arachidonic Acid results in increased activity of TRPA1 protein]
CTD PMID:15046718 NCBI chr 1:14,942,868...14,989,086
Ensembl chr 1:14,942,872...14,989,086
JBrowse link
G Trpc4 transient receptor potential cation channel, subfamily C, member 4 multiple interactions ISO TRPC4 protein affects the reaction [Arachidonic Acid results in increased transport of Calcium] CTD PMID:11830588 NCBI chr 3:54,063,441...54,225,892
Ensembl chr 3:54,063,456...54,225,892
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO [Arachidonic Acid co-treated with Phorbol 12,13-Dibutyrate] results in increased activity of TRPV1 protein CTD PMID:17038422 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
JBrowse link
G Trpv4 transient receptor potential cation channel, subfamily V, member 4 increases activity ISO Arachidonic Acid results in increased activity of TRPV4 protein CTD PMID:20956320 NCBI chr 5:114,760,213...114,796,497
Ensembl chr 5:114,760,213...114,796,482
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of Arachidonic Acid CTD PMID:15231852 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation ISO UGT1A10 protein results in increased glucuronidation of Arachidonic Acid CTD PMID:15231852 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of Arachidonic Acid CTD PMID:15231852 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 increases glucuronidation ISO UGT1A4 protein results in increased glucuronidation of Arachidonic Acid CTD PMID:15231852 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of Arachidonic Acid CTD PMID:15231852 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of Arachidonic Acid CTD PMID:15231852 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions
increases expression
ISO
EXP
[PTGS2 co-treated with Arachidonic Acid] results in increased expression of VEGFA
[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein; [Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK1 protein]; CYP2C23 mRNA promotes the reaction [[Arachidonic Acid co-treated with VEGFA protein] results in increased phosphorylation of MAPK3 protein]
Arachidonic Acid results in increased expression of VEGFA mRNA
CTD PMID:12821125 PMID:18388244 PMID:19464254 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide increases expression ISO Arachidonic Acid results in increased expression of YWHAZ mRNA CTD PMID:16704987 NCBI chr15:36,770,505...36,803,228
Ensembl chr15:36,771,014...36,797,173
JBrowse link
G Zfp36 zinc finger protein 36 increases expression EXP Arachidonic Acid results in increased expression of ZFP36 mRNA CTD PMID:8764118 NCBI chr 7:28,076,208...28,078,680
Ensembl chr 7:28,076,209...28,079,678
JBrowse link
arachidonoyl-CoA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO arachidonyl-coenzyme A binds to and results in increased activity of PPARA protein CTD PMID:11139385 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
arachidonyl-2'-chloroethylamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agrp agouti related neuropeptide decreases expression ISO arachidonyl-2-chloroethylamide results in decreased expression of AGRP mRNA CTD PMID:26468265 NCBI chr 8:106,293,327...106,306,477
Ensembl chr 8:106,293,330...106,364,025
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases phosphorylation EXP arachidonyl-2-chloroethylamide results in decreased phosphorylation of AKT1 protein CTD PMID:26847930 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Angpt1 angiopoietin 1 multiple interactions ISO arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of ANGPT1 protein] CTD PMID:26467187 NCBI chr15:42,288,063...42,540,373
Ensembl chr15:42,288,119...42,540,373
JBrowse link
G Angpt2 angiopoietin 2 multiple interactions ISO arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of ANGPT2 protein] CTD PMID:26467187 NCBI chr 8:18,740,279...18,791,578
Ensembl chr 8:18,740,279...18,791,578
JBrowse link
G Avp arginine vasopressin multiple interactions ISO arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of AVP mRNA] CTD PMID:26468265 NCBI chr 2:130,422,540...130,424,508
Ensembl chr 2:130,422,540...130,424,474
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased expression of BCL2 protein
[Streptozocin co-treated with arachidonyl-2-chloroethylamide] results in increased expression of BCL2 protein
CTD PMID:30607903 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Cartpt CART prepropeptide multiple interactions
decreases expression
ISO [arachidonyl-2-chloroethylamide co-treated with Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of CARTPT mRNA
arachidonyl-2-chloroethylamide results in decreased expression of CARTPT mRNA
CTD PMID:26468265 NCBI chr13:100,034,991...100,037,191
Ensembl chr13:100,034,997...100,037,599
JBrowse link
G Casp3 caspase 3 multiple interactions EXP arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein] CTD PMID:31256211 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp9 caspase 9 multiple interactions EXP arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein] CTD PMID:31256211 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions
increases expression
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA] CTD PMID:29033935 NCBI chr11:83,553,410...83,555,509
Ensembl chr11:83,553,410...83,555,509
JBrowse link
G Cd86 CD86 antigen increases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]
CTD PMID:29033935 NCBI chr16:36,389,318...36,486,439
Ensembl chr16:36,424,231...36,486,443
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO
EXP
CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of CCL4 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of CD86 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of ESRRG mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]
CTD PMID:12734338 PMID:27455076 PMID:29033935 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Dagla diacylglycerol lipase, alpha increases expression
multiple interactions
EXP
ISO
arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA; arachidonyl-2-chloroethylamide results in increased expression of DAGLA protein
ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]
arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to DAGLA promoter]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA protein]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]
CTD PMID:31912162 NCBI chr19:10,222,629...10,282,323
Ensembl chr19:10,222,629...10,282,241
JBrowse link
G Daglb diacylglycerol lipase, beta multiple interactions
increases expression
ISO
EXP
ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]
arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to DAGLB promoter]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]
CTD PMID:31912162 NCBI chr 5:143,450,239...143,490,197
Ensembl chr 5:143,450,339...143,491,697
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions EXP arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased expression of DDIT3 protein] CTD PMID:31256211 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Drd2 dopamine receptor D2 decreases expression ISO arachidonyl-2-chloroethylamide results in decreased expression of DRD2 mRNA CTD PMID:22791651 NCBI chr 9:49,251,703...49,319,468
Ensembl chr 9:49,251,927...49,319,477
JBrowse link
G Esrrg estrogen-related receptor gamma increases expression
multiple interactions
ISO
EXP
arachidonyl-2-chloroethylamide results in increased expression of ESRRG mRNA
arachidonyl-2-chloroethylamide results in increased expression of ESRRG mRNA; arachidonyl-2-chloroethylamide results in increased expression of ESRRG protein
arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to DAGLA promoter]; arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to DAGLB promoter]; arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to FGF21 promoter]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of ESRRG mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA protein]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased secretion of FGF21 protein]
ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLA mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of DAGLB mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]
CTD PMID:27455076 PMID:30019168 PMID:31912162 NCBI chr 1:187,340,707...187,947,082
Ensembl chr 1:187,340,988...187,947,082
JBrowse link
G Fga fibrinogen alpha chain increases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased expression of FGA mRNA
GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGA mRNA]
CTD PMID:30019168 NCBI chr 3:82,933,460...82,940,934
Ensembl chr 3:82,933,383...82,940,934
JBrowse link
G Fgb fibrinogen beta chain increases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased expression of FGB mRNA
GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGB mRNA]
CTD PMID:30019168 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgf21 fibroblast growth factor 21 increases expression
increases secretion
multiple interactions
EXP
ISO
arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA; arachidonyl-2-chloroethylamide results in increased expression of FGF21 protein
arachidonyl-2-chloroethylamide results in increased secretion of FGF21 protein
ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]
arachidonyl-2-chloroethylamide promotes the reaction [ESRRG protein binds to FGF21 promoter]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; ESRRG protein affects the reaction [arachidonyl-2-chloroethylamide results in increased secretion of FGF21 protein]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGF21 mRNA]; GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased secretion of FGF21 protein]
CTD PMID:27455076 NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
JBrowse link
G Fgg fibrinogen gamma chain increases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased expression of FGG mRNA
GSK5182 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of FGG mRNA]
CTD PMID:30019168 NCBI chr 3:82,915,031...82,922,363
Ensembl chr 3:82,915,031...82,922,356
JBrowse link
G Foxo1 forkhead box O1 multiple interactions
decreases phosphorylation
EXP FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NFE2L2 mRNA]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NRF1 mRNA]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of PPARGC1A mRNA]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of TFAM mRNA]
arachidonyl-2-chloroethylamide results in decreased phosphorylation of FOXO1 protein
CTD PMID:26847930 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions EXP arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]] CTD PMID:26847930 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Gsr glutathione reductase multiple interactions EXP arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein results in increased activity of GSR protein] CTD PMID:26671069 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Hcrt hypocretin increases expression ISO arachidonyl-2-chloroethylamide results in increased expression of HCRT mRNA CTD PMID:26468265 NCBI chr11:100,652,519...100,653,757
Ensembl chr11:100,651,895...100,653,757
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of IL6 mRNA]
CTD PMID:29033935 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ins1 insulin I multiple interactions EXP [arachidonyl-2-chloroethylamide co-treated with Glucose] results in increased secretion of INS1 protein; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein results in increased activity of GSR protein]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] CTD PMID:26671069 PMID:26847930 PMID:30761839 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK1 protein
arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK1 protein; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK1 protein]
AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK1 protein]; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK1 protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK1 protein]
CTD PMID:12734338 PMID:19477951 PMID:26467187 PMID:29033935 PMID:30607903 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions
increases phosphorylation
EXP
ISO
AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK3 protein]; arachidonyl-2-chloroethylamide promotes the reaction [Streptozocin results in increased phosphorylation of MAPK3 protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of MAPK3 protein]
arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK3 protein; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:12734338 PMID:19477951 PMID:26467187 PMID:29033935 PMID:30607903 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mpo myeloperoxidase increases activity
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased activity of MPO protein
Acetylcysteine inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]; SB 203580 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]
CTD PMID:32033504 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in decreased expression of NFE2L2 mRNA
FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NFE2L2 mRNA]
CTD PMID:26847930 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nos2 nitric oxide synthase 2, inducible increases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 protein]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 protein]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of NOS2 protein]
CTD PMID:29033935 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nrf1 nuclear respiratory factor 1 multiple interactions
decreases expression
EXP FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of NRF1 mRNA] CTD PMID:26847930 NCBI chr 6:30,047,984...30,153,462
Ensembl chr 6:30,047,987...30,153,457
JBrowse link
G Oxt oxytocin multiple interactions ISO arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of OXT mRNA]; arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased secretion of OXT protein] CTD PMID:26468265 NCBI chr 2:130,416,432...130,418,974
Ensembl chr 2:130,418,093...130,418,974
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions EXP arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein] CTD PMID:31256211 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions EXP arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] CTD PMID:26847930 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pmch pro-melanin-concentrating hormone multiple interactions
increases expression
ISO arachidonyl-2-chloroethylamide promotes the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of PMCH mRNA]
arachidonyl-2-chloroethylamide results in increased expression of PMCH mRNA
CTD PMID:26468265 NCBI chr10:87,926,934...87,928,236
Ensembl chr10:87,926,934...87,928,237
JBrowse link
G Pomc pro-opiomelanocortin-alpha decreases expression
multiple interactions
ISO arachidonyl-2-chloroethylamide results in decreased expression of POMC mRNA
arachidonyl-2-chloroethylamide inhibits the reaction [[Water deficiency co-treated with Sodium Chloride, Dietary deficiency] results in increased expression of POMC mRNA]
CTD PMID:26468265 NCBI chr12:4,004,945...4,010,643
Ensembl chr12:4,004,951...4,010,642
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions
decreases expression
EXP FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of PPARGC1A mRNA] CTD PMID:26847930 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
affects localization
EXP AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide affects the localization of RELA protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide affects the localization of RELA protein]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide affects the localization of RELA protein] CTD PMID:29033935 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Rhoa ras homolog family member A increases activity
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased activity of RHOA protein
AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of RHOA protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of RHOA protein]
CTD PMID:29033935 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Tfam transcription factor A, mitochondrial multiple interactions
decreases expression
EXP FOXO1 protein affects the reaction [arachidonyl-2-chloroethylamide results in decreased expression of TFAM mRNA] CTD PMID:26847930 NCBI chr10:71,061,298...71,074,157
Ensembl chr10:71,061,294...71,074,110
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
EXP arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA; arachidonyl-2-chloroethylamide results in increased expression of TNF protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; AM 281 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; CNR1 protein affects the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; Pertussis Toxin inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF mRNA]; Y 27632 inhibits the reaction [arachidonyl-2-chloroethylamide results in increased expression of TNF protein]
CTD PMID:29033935 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trp53 transformation related protein 53 multiple interactions EXP arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased phosphorylation of TRP53 protein] CTD PMID:31256211 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFA protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFA protein] CTD PMID:26467187 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfc vascular endothelial growth factor C multiple interactions ISO AM 251 inhibits the reaction [arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein]]; arachidonyl-2-chloroethylamide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of VEGFC protein] CTD PMID:26467187 NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
JBrowse link
cholesteryl arachidonate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase, hepatic multiple interactions EXP [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl arachidonate CTD PMID:24777581 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lipg lipase, endothelial multiple interactions
decreases abundance
EXP [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl arachidonate
LIPG gene mutant form results in decreased abundance of cholesteryl arachidonate
CTD PMID:24777581 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334
JBrowse link
cholesteryl linoleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lipc lipase, hepatic multiple interactions EXP [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linoleate CTD PMID:24777581 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lipg lipase, endothelial multiple interactions
affects abundance
EXP [LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl linoleate
LIPG gene mutant form affects the abundance of cholesteryl linoleate
CTD PMID:24777581 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334
JBrowse link
corn oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg8 ATP binding cassette subfamily G member 8 affects expression ISO Corn Oil affects the expression of ABCG8 mRNA CTD PMID:16360708 NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha increases expression ISO Corn Oil results in increased expression of ACACA mRNA CTD PMID:1973097 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Acly ATP citrate lyase affects expression ISO Corn Oil affects the expression of ACLY mRNA CTD PMID:16360708 NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826
JBrowse link
G Acot2 acyl-CoA thioesterase 2 affects expression ISO Corn Oil affects the expression of ACOT2 mRNA CTD PMID:16360708 NCBI chr12:84,034,635...84,040,651
Ensembl chr12:84,034,635...84,040,647
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions ISO Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein] CTD PMID:29165388 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Akr1b7 aldo-keto reductase family 1, member B7 affects expression ISO Corn Oil affects the expression of AKR1B7 mRNA CTD PMID:16360708 NCBI chr 6:34,389,297...34,400,072
Ensembl chr 6:34,389,269...34,400,077
JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 affects expression ISO Corn Oil affects the expression of ALDH1A1 mRNA CTD PMID:16360708 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829
JBrowse link
G Angptl4 angiopoietin-like 4 affects expression ISO Corn Oil affects the expression of ANGPTL4 mRNA CTD PMID:16360708 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Areg amphiregulin multiple interactions EXP [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA CTD PMID:32186404 NCBI chr 5:91,287,458...91,296,291
Ensembl chr 5:91,287,458...91,296,291
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO Corn Oil results in increased expression of BAD mRNA CTD PMID:22760963 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 multiple interactions ISO Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein] CTD PMID:29165388 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression ISO Corn Oil affects the expression of BHLHE40 mRNA CTD PMID:16360708 NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886
JBrowse link
G Bhmt betaine-homocysteine methyltransferase affects expression ISO Corn Oil affects the expression of BHMT mRNA CTD PMID:16360708 NCBI chr13:93,753,399...93,774,266
Ensembl chr13:93,753,183...93,774,469
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 increases expression EXP Corn Oil results in increased expression of BIRC3 mRNA CTD PMID:33263755 NCBI chr 9:7,848,698...7,873,199
Ensembl chr 9:7,848,700...7,873,187
JBrowse link
G Bmp1 bone morphogenetic protein 1 affects expression ISO Corn Oil affects the expression of BMP1 mRNA CTD PMID:16360708 NCBI chr14:70,711,998...70,758,280
Ensembl chr14:70,711,998...70,757,674
JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions EXP [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA CTD PMID:32186404 NCBI chr 2:133,394,079...133,404,816
Ensembl chr 2:133,394,079...133,404,805
JBrowse link
G Cadm1 cell adhesion molecule 1 affects expression ISO Corn Oil affects the expression of CADM1 mRNA CTD PMID:16360708 NCBI chr 9:47,441,468...47,773,578
Ensembl chr 9:47,441,471...47,769,413
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha multiple interactions EXP [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA CTD PMID:32186404 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Car6 carbonic anhydrase 6 increases expression EXP Corn Oil results in increased expression of CAR6 mRNA CTD PMID:33263755 NCBI chr 4:150,271,472...150,285,592
Ensembl chr 4:150,271,472...150,285,789
JBrowse link
G Card9 caspase recruitment domain family, member 9 increases expression EXP Corn Oil results in increased expression of CARD9 mRNA CTD PMID:33263755 NCBI chr 2:26,242,199...26,250,957
Ensembl chr 2:26,242,188...26,250,930
JBrowse link
G Cat catalase decreases expression
multiple interactions
EXP Corn Oil results in decreased expression of CAT protein
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in decreased expression of CAT protein
CTD PMID:36432690 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cav3 caveolin 3 decreases expression EXP Corn Oil results in decreased expression of CAV3 mRNA CTD PMID:33263755 NCBI chr 6:112,436,466...112,449,833
Ensembl chr 6:112,436,466...112,449,833
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
decreases expression
EXP
ISO
Corn Oil results in increased expression of CCL3 mRNA
Corn Oil results in decreased expression of CCL3 mRNA
CTD PMID:22760963 PMID:23409006 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccnd1 cyclin D1 affects expression ISO Corn Oil affects the expression of CCND1 mRNA CTD PMID:16360708 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Corn Oil results in decreased expression of CD36 mRNA CTD PMID:22760963 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cdhr1 cadherin-related family member 1 increases expression ISO Corn Oil results in increased expression of CDHR1 mRNA CTD PMID:22760963 NCBI chr14:36,799,806...36,820,304
Ensembl chr14:36,799,814...36,820,304
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A increases expression
affects expression
ISO Corn Oil results in increased expression of CDKN1A mRNA
Corn Oil affects the expression of CDKN1A mRNA
CTD PMID:16360708 PMID:22760963 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cenpt centromere protein T increases expression ISO Corn Oil results in increased expression of CENPT mRNA CTD PMID:22760963 NCBI chr 8:106,571,297...106,581,678
Ensembl chr 8:106,571,305...106,579,910
JBrowse link
G Cfb complement factor B increases expression ISO Corn Oil results in increased expression of CFB mRNA CTD PMID:22760963 NCBI chr17:35,075,350...35,081,492
Ensembl chr17:35,075,350...35,081,494
JBrowse link
G Cldn1 claudin 1 decreases expression EXP Corn Oil results in decreased expression of CLDN1 mRNA CTD PMID:33263755 NCBI chr16:26,175,395...26,190,589
Ensembl chr16:26,175,392...26,190,591
JBrowse link
G Cldn9 claudin 9 increases expression EXP Corn Oil results in increased expression of CLDN9 mRNA CTD PMID:33263755 NCBI chr17:23,901,558...23,903,000
Ensembl chr17:23,901,558...23,903,000
JBrowse link
G Cox7a1 cytochrome c oxidase subunit 7A1 decreases expression EXP Corn Oil results in decreased expression of COX7A1 mRNA CTD PMID:23409006 NCBI chr 7:29,883,596...29,885,455
Ensembl chr 7:29,883,569...29,885,503
JBrowse link
G Cox8b cytochrome c oxidase subunit 8B decreases expression EXP Corn Oil results in decreased expression of COX8B mRNA CTD PMID:23409006 NCBI chr 7:140,478,855...140,480,359
Ensembl chr 7:140,478,858...140,480,359
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver affects expression
multiple interactions
increases expression
ISO
EXP
Corn Oil affects the expression of CPT1A mRNA
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT1A mRNA
Corn Oil results in increased expression of CPT1A mRNA
CTD PMID:16360708 PMID:22760963 PMID:36432690 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions EXP [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT2 mRNA CTD PMID:36432690 NCBI chr 4:107,761,179...107,780,786
Ensembl chr 4:107,761,178...107,780,807
JBrowse link
G Crot carnitine O-octanoyltransferase affects expression
multiple interactions
ISO
EXP
Corn Oil affects the expression of CROT mRNA
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CROT mRNA
CTD PMID:16360708 PMID:36432690 NCBI chr 5:9,016,033...9,047,926
Ensembl chr 5:9,016,033...9,047,324
JBrowse link
G Ctsg cathepsin G increases expression ISO Corn Oil results in increased expression of CTSG mRNA CTD PMID:22760963 NCBI chr14:56,337,342...56,340,031
Ensembl chr14:56,337,338...56,340,031
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 affects expression ISO Corn Oil affects the expression of CYP17A1 mRNA CTD PMID:16360708 NCBI chr19:46,655,604...46,661,439
Ensembl chr19:46,655,604...46,661,611
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 affects expression ISO Corn Oil affects the expression of CYP7A1 mRNA CTD PMID:16360708 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 affects expression ISO Corn Oil affects the expression of CYP8B1 mRNA CTD PMID:16360708 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Ephx2 epoxide hydrolase 2, cytoplasmic affects expression ISO Corn Oil affects the expression of EPHX2 mRNA CTD PMID:16360708 NCBI chr14:66,321,821...66,361,971
Ensembl chr14:66,321,823...66,361,949
JBrowse link
G Ets1 E26 avian leukemia oncogene 1, 5' domain decreases expression ISO Corn Oil results in decreased expression of ETS1 mRNA CTD PMID:22760963 NCBI chr 9:32,547,501...32,669,116
Ensembl chr 9:32,547,517...32,669,116
JBrowse link
G Fabp1 fatty acid binding protein 1, liver multiple interactions ISO [Ethanol co-treated with Corn Oil] results in decreased expression of FABP1 mRNA CTD PMID:15016835 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fabp2 fatty acid binding protein 2, intestinal affects expression ISO Corn Oil affects the expression of FABP2 mRNA CTD PMID:16360708 NCBI chr 3:122,688,721...122,693,155
Ensembl chr 3:122,688,721...122,693,155
JBrowse link
G Fabp7 fatty acid binding protein 7, brain affects expression ISO Corn Oil affects the expression of FABP7 mRNA CTD PMID:16360708 NCBI chr10:57,661,019...57,664,546
Ensembl chr10:57,660,977...57,664,546
JBrowse link
G Fasn fatty acid synthase affects expression ISO Corn Oil affects the expression of FASN mRNA CTD PMID:16360708 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fcgrt Fc fragment of IgG receptor and transporter decreases expression ISO Corn Oil results in decreased expression of FCGRT mRNA CTD PMID:22760963 NCBI chr 7:44,742,417...44,753,246
Ensembl chr 7:44,742,414...44,753,275
JBrowse link
G Fgb fibrinogen beta chain affects expression ISO Corn Oil affects the expression of FGB mRNA CTD PMID:16360708 NCBI chr 3:82,949,553...82,957,170
Ensembl chr 3:82,947,448...82,957,170
JBrowse link
G Fgf21 fibroblast growth factor 21 affects expression ISO Corn Oil affects the expression of FGF21 mRNA CTD PMID:16360708 NCBI chr 7:45,263,314...45,264,914
Ensembl chr 7:45,263,310...45,264,914
JBrowse link
G Fst follistatin multiple interactions EXP [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA CTD PMID:32186404 NCBI chr13:114,588,798...114,595,522
Ensembl chr13:114,588,826...114,595,487
JBrowse link
G G0s2 G0/G1 switch gene 2 affects expression ISO Corn Oil affects the expression of G0S2 mRNA CTD PMID:16360708 NCBI chr 1:192,954,468...192,955,496
Ensembl chr 1:192,954,469...192,955,525
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha affects expression ISO Corn Oil affects the expression of GADD45A mRNA CTD PMID:16360708 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gal galanin and GMAP prepropeptide increases expression ISO Corn Oil results in increased expression of GAL mRNA CTD PMID:22760963 NCBI chr19:3,459,915...3,464,544
Ensembl chr19:3,459,915...3,464,544
JBrowse link
G Gck glucokinase affects expression ISO Corn Oil affects the expression of GCK mRNA CTD PMID:16360708 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081
JBrowse link
G Gjd2 gap junction protein, delta 2 increases expression EXP Corn Oil results in increased expression of GJD2 mRNA CTD PMID:33263755 NCBI chr 2:113,840,086...113,844,555
Ensembl chr 2:113,840,082...113,844,100
JBrowse link
G Gm7030 predicted gene 7030 increases expression ISO Corn Oil results in increased expression of RT1-CE5 mRNA CTD PMID:22760963 NCBI chr17:36,438,501...36,440,317
Ensembl chr17:36,420,611...36,440,317
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble affects expression ISO Corn Oil affects the expression of GOT1 mRNA CTD PMID:16360708 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial decreases expression ISO Corn Oil results in decreased expression of GOT2 mRNA CTD PMID:34987138 NCBI chr 8:96,590,761...96,615,029
Ensembl chr 8:96,590,762...96,615,175
JBrowse link
G Gpd2 glycerol phosphate dehydrogenase 2, mitochondrial affects expression ISO Corn Oil affects the expression of GPD2 mRNA CTD PMID:16360708 NCBI chr 2:57,127,690...57,260,731
Ensembl chr 2:57,127,647...57,260,731
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO [Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein; Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]; Orlistat inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein] CTD PMID:29479035 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 increases expression ISO Corn Oil results in increased expression of RT1-BB mRNA CTD PMID:22760963 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-Q1 histocompatibility 2, Q region locus 1 increases expression ISO Corn Oil results in increased expression of RT1-CE16 mRNA CTD PMID:22760963 NCBI chr17:35,539,503...35,547,118
Ensembl chr17:35,539,381...35,544,075
JBrowse link
G H2ac25 H2A clustered histone 25 affects expression ISO Corn Oil affects the expression of H2A mRNA CTD PMID:16360708 NCBI chr11:58,845,511...58,846,018
Ensembl chr11:58,845,511...58,847,656
JBrowse link
G Hal histidine ammonia lyase affects expression ISO Corn Oil affects the expression of HAL mRNA CTD PMID:16360708 NCBI chr10:93,324,630...93,352,623
Ensembl chr10:93,324,630...93,355,166
JBrowse link
G Hamp hepcidin antimicrobial peptide affects expression ISO Corn Oil affects the expression of HAMP mRNA CTD PMID:16360708 NCBI chr 7:30,641,793...30,643,454
Ensembl chr 7:30,641,793...30,643,457
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase affects expression ISO Corn Oil affects the expression of HMGCR mRNA CTD PMID:16360708 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Hoxa11 homeobox A11 multiple interactions EXP [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA CTD PMID:32186404 NCBI chr 6:52,219,086...52,222,784
Ensembl chr 6:52,219,086...52,222,790
JBrowse link
G Hp haptoglobin increases expression ISO Corn Oil results in increased expression of HP mRNA CTD PMID:22760963 NCBI chr 8:110,301,760...110,305,804
Ensembl chr 8:110,301,760...110,305,804
JBrowse link
G Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 increases expression EXP Corn Oil results in increased expression of HSP90AA1 mRNA CTD PMID:33263755 NCBI chr12:110,657,470...110,662,829
Ensembl chr12:110,657,039...110,669,162
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase affects expression ISO Corn Oil affects the expression of IDI1 mRNA CTD PMID:16360708 NCBI chr13:8,935,642...8,942,432
Ensembl chr13:8,935,537...8,942,487
JBrowse link
G Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 increases expression
affects expression
ISO Corn Oil results in increased expression of IGF2BP2 mRNA
Corn Oil affects the expression of IGF2BP2 mRNA
CTD PMID:22760963 NCBI chr16:21,877,759...21,982,049
Ensembl chr16:21,877,759...21,982,049
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 affects expression ISO Corn Oil affects the expression of IGFBP1 mRNA CTD PMID:16360708 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Ihh Indian hedgehog multiple interactions EXP [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA CTD PMID:32186404 NCBI chr 1:74,984,474...74,990,831
Ensembl chr 1:74,984,474...74,990,831
JBrowse link
G Il12b interleukin 12b increases secretion ISO Corn Oil results in increased secretion of IL12B protein CTD PMID:33263755 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il18 interleukin 18 increases expression EXP Corn Oil results in increased expression of IL18 mRNA CTD PMID:33263755 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1a interleukin 1 alpha increases secretion ISO Corn Oil results in increased secretion of IL1A protein CTD PMID:33263755 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases secretion ISO Corn Oil results in increased secretion of IL1B protein CTD PMID:33263755 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO Corn Oil results in increased expression of IL1RN mRNA CTD PMID:22760963 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il4 interleukin 4 decreases expression
increases expression
increases secretion
EXP
ISO
Corn Oil results in decreased expression of IL4 mRNA
Corn Oil results in increased expression of IL4 mRNA
Corn Oil results in increased secretion of IL4 protein
CTD PMID:23409006 PMID:33263755 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6ra interleukin 6 receptor, alpha increases expression ISO Corn Oil results in increased expression of IL6R mRNA CTD PMID:22760963 NCBI chr 3:89,776,631...89,820,503
Ensembl chr 3:89,771,366...89,820,503
JBrowse link
G Il9 interleukin 9 increases secretion ISO Corn Oil results in increased secretion of IL9 protein CTD PMID:33263755 NCBI chr13:56,627,090...56,630,070
Ensembl chr13:56,627,090...56,630,059
JBrowse link
G Inhbe inhibin beta-E affects expression ISO Corn Oil affects the expression of INHBE mRNA CTD PMID:16360708 NCBI chr10:127,185,271...127,187,717
Ensembl chr10:127,184,726...127,190,280
JBrowse link
G Ins1 insulin I multiple interactions ISO Corn Oil inhibits the reaction [Glucose results in increased expression of INS1 protein] CTD PMID:29165388 NCBI chr19:52,252,735...52,253,453
Ensembl chr19:52,252,735...52,253,914
JBrowse link
G Irak1 interleukin-1 receptor-associated kinase 1 increases expression EXP Corn Oil results in increased expression of IRAK1 mRNA CTD PMID:33263755 NCBI chr  X:73,057,520...73,067,527
Ensembl chr  X:73,057,520...73,067,524
JBrowse link
G Irf5 interferon regulatory factor 5 increases expression EXP Corn Oil results in increased expression of IRF5 mRNA CTD PMID:33263755 NCBI chr 6:29,526,129...29,541,874
Ensembl chr 6:29,526,624...29,541,870
JBrowse link
G Irf7 interferon regulatory factor 7 increases expression EXP Corn Oil results in increased expression of IRF7 mRNA CTD PMID:33263755 NCBI chr 7:140,843,096...140,846,412
Ensembl chr 7:140,842,619...140,846,394
JBrowse link
G Jun jun proto-oncogene increases expression EXP Corn Oil results in increased expression of JUN mRNA CTD PMID:33263755 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) affects expression ISO Corn Oil affects the expression of KLF2 mRNA CTD PMID:16360708 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Lcat lecithin cholesterol acyltransferase multiple interactions EXP [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of LCAT mRNA CTD PMID:36432690 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Corn Oil results in increased expression of LCN2 mRNA CTD PMID:22760963 NCBI chr 2:32,274,649...32,277,751
Ensembl chr 2:32,274,645...32,278,264
JBrowse link
G Lep leptin multiple interactions ISO Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein] CTD PMID:29165388 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Lgals1 lectin, galactose binding, soluble 1 increases expression ISO Corn Oil results in increased expression of LGALS1 mRNA CTD PMID:22760963 NCBI chr15:78,810,925...78,814,665
Ensembl chr15:78,810,925...78,814,665
JBrowse link
G Lox lysyl oxidase multiple interactions EXP Corn Oil results in increased activity of and results in increased cleavage of LOX protein CTD PMID:26240151 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939
JBrowse link
G Ly75 lymphocyte antigen 75 increases expression ISO Corn Oil results in increased expression of LY75 mRNA CTD PMID:22760963 NCBI chr 2:60,122,447...60,213,617
Ensembl chr 2:60,122,447...60,213,647
JBrowse link
G Map2k1 mitogen-activated protein kinase kinase 1 increases expression EXP Corn Oil results in increased expression of MAP2K1 mRNA CTD PMID:33263755 NCBI chr 9:64,093,066...64,160,887
Ensembl chr 9:64,093,052...64,160,913
JBrowse link
G Map2k3 mitogen-activated protein kinase kinase 3 increases expression EXP Corn Oil results in increased expression of MAP2K3 mRNA CTD PMID:33263755 NCBI chr11:60,822,880...60,843,637
Ensembl chr11:60,822,859...60,843,637
JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 affects expression ISO Corn Oil affects the expression of MAP2K6 mRNA CTD PMID:16360708 NCBI chr11:110,289,928...110,416,348
Ensembl chr11:110,289,948...110,416,348
JBrowse link
G Map3k7 mitogen-activated protein kinase kinase kinase 7 increases expression EXP Corn Oil results in increased expression of MAP3K7 mRNA CTD PMID:33263755 NCBI chr 4:31,963,659...32,023,470
Ensembl chr 4:31,964,097...32,023,467
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases expression EXP Corn Oil results in increased expression of MAPK1 mRNA CTD PMID:33263755 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 increases expression EXP Corn Oil results in increased expression of MAPK14 mRNA CTD PMID:33263755 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases expression EXP Corn Oil results in increased expression of MAPK3 mRNA CTD PMID:33263755 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 decreases expression ISO Corn Oil results in decreased expression of MDM2 mRNA CTD PMID:22760963 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression ISO Corn Oil results in increased expression of MGMT mRNA CTD PMID:22760963 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995
JBrowse link
G Mgst2 microsomal glutathione S-transferase 2 increases expression ISO Corn Oil results in increased expression of MGST2 mRNA CTD PMID:22760963 NCBI chr 3:51,544,179...51,590,096
Ensembl chr 3:51,567,781...51,590,098
JBrowse link
G Mlycd malonyl-CoA decarboxylase decreases expression ISO Corn Oil results in decreased expression of MLYCD mRNA CTD PMID:22760963 NCBI chr 8:120,121,591...120,148,577
Ensembl chr 8:120,121,617...120,137,841
JBrowse link
G Msmo1 methylsterol monoxygenase 1 affects expression ISO Corn Oil affects the expression of MSMO1 mRNA CTD PMID:16360708 NCBI chr 8:65,171,157...65,186,822
Ensembl chr 8:65,171,173...65,186,826
JBrowse link
G Mtr 5-methyltetrahydrofolate-homocysteine methyltransferase multiple interactions EXP [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of MTR mRNA CTD PMID:36432690 NCBI chr13:12,196,217...12,273,090
Ensembl chr13:12,197,598...12,272,999
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 increases expression EXP Corn Oil results in increased expression of MYD88 mRNA CTD PMID:33263755 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 decreases activity EXP Corn Oil results in decreased activity of NFE2L2 protein CTD PMID:30203046 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha increases expression EXP Corn Oil results in increased expression of NFKBIA mRNA CTD PMID:33263755 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nlrc4 NLR family, CARD domain containing 4 increases expression EXP Corn Oil results in increased expression of NLRC4 mRNA CTD PMID:33263755 NCBI chr17:74,733,254...74,766,140
Ensembl chr17:74,732,433...74,766,137
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 affects expression ISO Corn Oil affects the expression of NR1H4 mRNA CTD PMID:16360708 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Corn Oil results in increased expression of NR4A2 mRNA CTD PMID:22760963 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
JBrowse link
G Nsmce3 NSE3 homolog, SMC5-SMC6 complex component affects expression ISO Corn Oil affects the expression of NSMCE3 mRNA CTD PMID:16360708 NCBI chr 7:64,521,430...64,522,788
Ensembl chr 7:64,516,800...64,522,745
JBrowse link
G Oat ornithine aminotransferase affects expression ISO Corn Oil affects the expression of OAT mRNA CTD PMID:16360708 NCBI chr 7:132,159,204...132,178,127
Ensembl chr 7:132,159,207...132,178,127
JBrowse link
G Osgin1 oxidative stress induced growth inhibitor 1 affects expression ISO Corn Oil affects the expression of OSGIN1 mRNA CTD PMID:16360708 NCBI chr 8:120,160,874...120,172,996
Ensembl chr 8:120,160,863...120,172,995
JBrowse link
G P2rx5 purinergic receptor P2X, ligand-gated ion channel, 5 affects expression ISO Corn Oil affects the expression of P2RX5 mRNA CTD PMID:16360708 NCBI chr11:73,029,164...73,063,509
Ensembl chr11:73,051,247...73,063,511
JBrowse link
G Pax8 paired box 8 affects expression ISO Corn Oil affects the expression of PAX8 mRNA CTD PMID:16360708 NCBI chr 2:24,310,563...24,365,611
Ensembl chr 2:24,310,572...24,365,611
JBrowse link
G Pdgfa platelet derived growth factor, alpha affects expression ISO Corn Oil affects the expression of PDGFA mRNA CTD PMID:16360708 NCBI chr 5:138,961,761...138,986,336
Ensembl chr 5:138,961,769...138,983,125
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide increases expression ISO Corn Oil results in increased expression of PDGFRB mRNA CTD PMID:22760963 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Pdlim1 PDZ and LIM domain 1 (elfin) affects expression ISO Corn Oil affects the expression of PDLIM1 mRNA CTD PMID:16360708 NCBI chr19:40,210,683...40,260,060
Ensembl chr19:40,209,617...40,260,286
JBrowse link
G Pdlim2 PDZ and LIM domain 2 affects expression ISO Corn Oil affects the expression of PDLIM2 mRNA CTD PMID:16360708 NCBI chr14:70,401,667...70,415,140
Ensembl chr14:70,401,667...70,415,130
JBrowse link
G Pgf placental growth factor increases expression ISO Corn Oil results in increased expression of PGF mRNA CTD PMID:22760963 NCBI chr12:85,213,413...85,224,087
Ensembl chr12:85,213,409...85,224,564
JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 affects expression ISO Corn Oil affects the expression of PGRMC2 mRNA CTD PMID:16360708 NCBI chr 3:41,020,772...41,037,443
Ensembl chr 3:41,020,761...41,037,481
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha increases expression EXP Corn Oil results in increased expression of PIK3CA mRNA CTD PMID:33263755 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Plin2 perilipin 2 affects expression ISO Corn Oil affects the expression of PLIN2 mRNA CTD PMID:16360708 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
JBrowse link
G Prlr prolactin receptor affects expression ISO Corn Oil affects the expression of PRLR mRNA CTD PMID:16360708 NCBI chr15:10,177,324...10,349,276
Ensembl chr15:10,177,324...10,349,266
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP [Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of PTGS2 mRNA CTD PMID:32186404 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Ptprf protein tyrosine phosphatase receptor type F affects expression ISO Corn Oil affects the expression of PTPRF mRNA CTD PMID:16360708 NCBI chr 4:118,065,410...118,148,602
Ensembl chr 4:118,065,410...118,148,602
JBrowse link
G Pycard PYD and CARD domain containing increases expression EXP Corn Oil results in increased expression of PYCARD mRNA CTD PMID:33263755 NCBI chr 7:127,590,545...127,593,039
Ensembl chr 7:127,588,880...127,593,039
JBrowse link
G Rac1 Rac family small GTPase 1 increases expression EXP Corn Oil results in increased expression of RAC1 mRNA CTD PMID:33263755 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791
JBrowse link
G Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 increases expression EXP Corn Oil results in increased expression of RIPK1 mRNA CTD PMID:33263755 NCBI chr13:34,181,072...34,219,153
Ensembl chr13:34,186,346...34,221,130
JBrowse link
G Ripk2 receptor (TNFRSF)-interacting serine-threonine kinase 2 increases expression EXP Corn Oil results in increased expression of RIPK2 mRNA CTD PMID:33263755 NCBI chr 4:16,122,740...16,163,674
Ensembl chr 4:16,122,733...16,163,647
JBrowse link
G S100a8 S100 calcium binding protein A8 (calgranulin A) increases expression ISO Corn Oil results in increased expression of S100A8 mRNA CTD PMID:22760963 NCBI chr 3:90,576,378...90,577,341
Ensembl chr 3:90,576,285...90,577,342
JBrowse link
G S100a9 S100 calcium binding protein A9 (calgranulin B) increases expression ISO Corn Oil results in increased expression of S100A9 mRNA CTD PMID:22760963 NCBI chr 3:90,599,937...90,603,028
Ensembl chr 3:90,599,939...90,603,028
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 affects expression ISO Corn Oil affects the expression of SCD1 mRNA CTD PMID:16360708 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Scn1b sodium channel, voltage-gated, type I, beta affects expression ISO Corn Oil affects the expression of SCN1B mRNA CTD PMID:16360708 NCBI chr 7:30,815,949...30,826,436
Ensembl chr 7:30,815,949...30,826,428
JBrowse link
G Sds serine dehydratase affects expression ISO Corn Oil affects the expression of SDS mRNA CTD PMID:16360708 NCBI chr 5:120,614,612...120,621,997
Ensembl chr 5:120,614,591...120,621,997
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 decreases expression ISO Corn Oil results in decreased expression of SFRP2 mRNA CTD PMID:22760963 NCBI chr 3:83,673,628...83,681,621
Ensembl chr 3:83,673,628...83,681,623
JBrowse link
G Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 multiple interactions EXP [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of SLC25A20 mRNA CTD PMID:36432690 NCBI chr 9:108,539,335...108,561,841
Ensembl chr 9:108,539,287...108,561,840
JBrowse link
G Slc25a25 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25 affects expression ISO Corn Oil affects the expression of SLC25A25 mRNA CTD PMID:16360708 NCBI chr 2:32,304,499...32,341,482
Ensembl chr 2:32,304,499...32,341,457
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions
decreases activity
EXP [Corn Oil co-treated with Iron, Dietary] results in decreased activity of SOD1 protein; [Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]; Iron, Dietary promotes the reaction [Corn Oil results in decreased activity of SOD1 protein] CTD PMID:17194920 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sparc secreted acidic cysteine rich glycoprotein increases expression ISO Corn Oil results in increased expression of SPARC mRNA CTD PMID:22760963 NCBI chr11:55,284,985...55,310,906
Ensembl chr11:55,285,326...55,314,009
JBrowse link
G Sqle squalene epoxidase affects expression ISO Corn Oil affects the expression of SQLE mRNA CTD PMID:16360708 NCBI chr15:59,186,941...59,203,042
Ensembl chr15:59,186,926...59,203,041
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 affects expression ISO Corn Oil affects the expression of SREBF1 mRNA CTD PMID:16360708 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Sstr3 somatostatin receptor 3 decreases expression ISO Corn Oil results in decreased expression of SSTR3 mRNA CTD PMID:22760963 NCBI chr15:78,421,214...78,433,565
Ensembl chr15:78,421,208...78,428,885
JBrowse link
G Sugt1 SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae) increases expression EXP Corn Oil results in increased expression of SUGT1 mRNA CTD PMID:33263755 NCBI chr14:79,825,100...79,868,237
Ensembl chr14:79,825,131...79,872,636
JBrowse link
G Syk spleen tyrosine kinase increases expression EXP Corn Oil results in increased expression of SYK mRNA CTD PMID:23409006 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828
JBrowse link
G Tac1 tachykinin 1 decreases expression ISO Corn Oil results in decreased expression of TAC1 mRNA CTD PMID:22760963 NCBI chr 6:7,555,061...7,562,978
Ensembl chr 6:7,554,879...7,565,834
JBrowse link
G Tat tyrosine aminotransferase affects expression ISO Corn Oil affects the expression of TAT mRNA CTD PMID:16360708 NCBI chr 8:110,712,710...110,726,436
Ensembl chr 8:110,717,069...110,726,435
JBrowse link
G Tbc1d14 TBC1 domain family, member 14 affects expression ISO Corn Oil affects the expression of TBC1D14 mRNA CTD PMID:16360708 NCBI chr 5:36,647,948...36,743,611
Ensembl chr 5:36,647,948...36,750,620
JBrowse link
G Tgfa transforming growth factor alpha decreases expression ISO Corn Oil results in decreased expression of TGFA mRNA CTD PMID:22760963 NCBI chr 6:86,172,020...86,252,726
Ensembl chr 6:86,172,205...86,252,701
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 increases expression EXP Corn Oil results in increased expression of TICAM1 mRNA CTD PMID:33263755 NCBI chr17:56,576,462...56,583,767
Ensembl chr17:56,576,319...56,583,786
JBrowse link
G Tjp2 tight junction protein 2 increases expression EXP Corn Oil results in increased expression of TJP2 mRNA CTD PMID:33263755 NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394
JBrowse link
G Tjp3 tight junction protein 3 increases expression EXP Corn Oil results in increased expression of TJP3 mRNA CTD PMID:33263755 NCBI chr10:81,109,022...81,127,415
Ensembl chr10:81,109,041...81,127,415
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a increases expression EXP Corn Oil results in increased expression of TNFRSF1A mRNA CTD PMID:33263755 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tollip toll interacting protein increases expression EXP Corn Oil results in increased expression of TOLLIP mRNA CTD PMID:33263755 NCBI chr 7:141,435,317...141,456,198
Ensembl chr 7:141,428,550...141,472,244
JBrowse link
G Tpcn2 two pore segment channel 2 affects expression ISO Corn Oil affects the expression of TPCN2 mRNA CTD PMID:16360708 NCBI chr 7:144,735,370...144,837,743
Ensembl chr 7:144,740,261...144,837,748
JBrowse link
G Tpt1 tumor protein, translationally-controlled 1 increases expression ISO Corn Oil results in increased expression of TPT1 mRNA CTD PMID:22760963 NCBI chr14:76,082,771...76,085,743
Ensembl chr14:76,082,533...76,085,965
JBrowse link
G Vegfb vascular endothelial growth factor B decreases expression ISO Corn Oil results in decreased expression of VEGFB mRNA CTD PMID:22760963 NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019
JBrowse link
G Vnn1 vanin 1 affects expression ISO Corn Oil affects the expression of VNN1 mRNA CTD PMID:16360708 NCBI chr10:23,770,586...23,781,242
Ensembl chr10:23,770,586...23,781,241
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression EXP Corn Oil results in decreased expression of XIAP mRNA CTD PMID:33263755 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
G Xpnpep2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound affects expression ISO Corn Oil affects the expression of XPNPEP2 mRNA CTD PMID:16360708 NCBI chr  X:47,195,790...47,225,859
Ensembl chr  X:47,197,602...47,225,858
JBrowse link
G Zdhhc23 zinc finger, DHHC domain containing 23 affects expression ISO Corn Oil affects the expression of ZDHHC23 mRNA CTD PMID:16360708 NCBI chr16:43,785,396...43,800,295
Ensembl chr16:43,785,396...43,800,154
JBrowse link
gamma-linolenic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c20 aldo-keto reductase family 1, member C20 increases expression ISO gamma-Linolenic Acid results in increased expression of AKR1C1 mRNA CTD PMID:20664735 NCBI chr13:4,536,855...4,573,353
Ensembl chr13:4,536,848...4,573,344
JBrowse link
G Akr1c6 aldo-keto reductase family 1, member C6 increases expression ISO gamma-Linolenic Acid results in increased expression of AKR1C4 mRNA CTD PMID:20664735 NCBI chr13:4,484,354...4,507,529
Ensembl chr13:4,484,305...4,507,876
JBrowse link
G Apoh apolipoprotein H decreases expression ISO gamma-Linolenic Acid results in decreased expression of APOH mRNA CTD PMID:20664735 NCBI chr11:108,286,123...108,305,222
Ensembl chr11:108,234,180...108,305,222
JBrowse link
G Ar androgen receptor multiple interactions ISO gamma-Linolenic Acid inhibits the reaction [Metribolone results in increased activity of AR protein] CTD PMID:18324785 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO gamma-Linolenic Acid results in increased expression of ASAH1 mRNA CTD PMID:20664735 NCBI chr 8:41,793,683...41,850,681
Ensembl chr 8:41,793,234...41,827,810
JBrowse link
G Casp3 caspase 3 increases activity ISO gamma-Linolenic Acid results in increased activity of CASP3 protein CTD PMID:16857180 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO gamma-Linolenic Acid results in decreased expression of CCNA2 protein CTD PMID:15318936 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
JBrowse link
G Ccne1 cyclin E1 decreases expression ISO gamma-Linolenic Acid results in decreased expression of CCNE1 protein CTD PMID:15318936 NCBI chr 7:37,797,409...37,806,915
Ensembl chr 7:37,797,409...37,806,959
JBrowse link
G Cdk1 cyclin dependent kinase 1 decreases expression ISO gamma-Linolenic Acid results in decreased expression of CDK1 protein CTD PMID:15318936 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
JBrowse link
G Cldn5 claudin 5 multiple interactions ISO [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of CLDN5 protein; [gamma-Linolenic Acid co-treated with Iodine] results in increased expression of and results in increased localization of CLDN5 protein; [Selenium co-treated with gamma-Linolenic Acid] results in increased expression of and results in increased localization of CLDN5 protein; gamma-Linolenic Acid results in increased expression of and results in increased localization of CLDN5 protein CTD PMID:16514648 NCBI chr16:18,595,597...18,597,012
Ensembl chr16:18,595,597...18,597,012
JBrowse link
G Clta clathrin light chain A increases expression ISO gamma-Linolenic Acid results in increased expression of CLTA mRNA CTD PMID:20664735 NCBI chr 4:44,003,816...44,032,846
Ensembl chr 4:44,004,452...44,032,846
JBrowse link
G Fth1 ferritin heavy polypeptide 1 increases expression ISO gamma-Linolenic Acid results in increased expression of FTH1 mRNA CTD PMID:20664735 NCBI chr19:9,957,964...9,962,475
Ensembl chr19:9,957,962...9,962,462
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases activity
increases expression
ISO gamma-Linolenic Acid results in increased activity of GCLC protein
gamma-Linolenic Acid results in increased expression of GCLC mRNA
CTD PMID:17092368 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767
JBrowse link
G Gm40318 predicted gene, 40318 increases expression ISO gamma-Linolenic Acid results in increased expression of S100P mRNA CTD PMID:20664735 NCBI chr 5:36,919,848...36,924,763
Ensembl chr 5:36,919,961...36,924,039
JBrowse link
G Grk5 G protein-coupled receptor kinase 5 increases expression ISO gamma-Linolenic Acid results in increased expression of GRK5 mRNA CTD PMID:20664735 NCBI chr19:60,877,995...61,084,406
Ensembl chr19:60,878,187...61,084,406
JBrowse link
G Hexb hexosaminidase B increases expression ISO gamma-Linolenic Acid results in increased expression of HEXB mRNA CTD PMID:20664735 NCBI chr13:97,312,839...97,334,865
Ensembl chr13:97,312,839...97,334,865
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO gamma-Linolenic Acid results in increased expression of HMOX1 mRNA; gamma-Linolenic Acid results in increased expression of HMOX1 protein CTD PMID:17092368 PMID:20664735 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Il2 interleukin 2 affects expression ISO gamma-Linolenic Acid affects the expression of IL2 protein CTD PMID:9415022 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Junb jun B proto-oncogene decreases expression ISO gamma-Linolenic Acid results in decreased expression of JUNB protein CTD PMID:15318936 NCBI chr 8:85,703,538...85,705,377
Ensembl chr 8:85,701,113...85,705,347
JBrowse link
G Kynu kynureninase decreases expression ISO gamma-Linolenic Acid results in decreased expression of KYNU mRNA CTD PMID:20664735 NCBI chr 2:43,445,270...43,572,734
Ensembl chr 2:43,445,341...43,572,734
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 decreases expression ISO gamma-Linolenic Acid results in decreased expression of MAPK3 protein CTD PMID:15318936 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mmp11 matrix metallopeptidase 11 decreases expression ISO gamma-Linolenic Acid results in decreased expression of MMP11 mRNA CTD PMID:20664735 NCBI chr10:75,759,056...75,768,336
Ensembl chr10:75,759,056...75,772,330
JBrowse link
G Myc myelocytomatosis oncogene decreases expression ISO gamma-Linolenic Acid results in decreased expression of MYC protein CTD PMID:15318936 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223
JBrowse link
G Ocln occludin multiple interactions ISO [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of OCLN protein; [gamma-Linolenic Acid co-treated with Iodine] results in increased expression of and results in increased localization of OCLN protein; [Selenium co-treated with gamma-Linolenic Acid] results in increased expression of and results in increased localization of OCLN protein; gamma-Linolenic Acid results in increased expression of and results in increased localization of OCLN protein CTD PMID:16514648 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 increases cleavage EXP gamma-Linolenic Acid results in increased cleavage of PARP1 protein CTD PMID:10403056 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression ISO gamma-Linolenic Acid results in decreased expression of PCNA mRNA CTD PMID:20664735 NCBI chr 2:132,091,206...132,095,100
Ensembl chr 2:132,091,082...132,095,234
JBrowse link
G Pdlim1 PDZ and LIM domain 1 (elfin) decreases expression ISO gamma-Linolenic Acid results in decreased expression of PDLIM1 mRNA CTD PMID:20664735 NCBI chr19:40,210,683...40,260,060
Ensembl chr19:40,209,617...40,260,286
JBrowse link
G Plin2 perilipin 2 increases expression ISO gamma-Linolenic Acid results in increased expression of PLIN2 mRNA CTD PMID:20664735 NCBI chr 4:86,545,147...86,588,518
Ensembl chr 4:86,566,623...86,588,297
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO gamma-Linolenic Acid binds to and results in increased activity of PPARA protein CTD PMID:10403814 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions ISO gamma-Linolenic Acid binds to and results in increased activity of PPARG protein CTD PMID:15318936 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO gamma-Linolenic Acid results in increased expression of PTGR1 mRNA CTD PMID:20664735 NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO gamma-Linolenic Acid results in increased expression of PTGS2 mRNA CTD PMID:17092368 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Skp2 S-phase kinase-associated protein 2 decreases expression ISO gamma-Linolenic Acid results in decreased expression of SKP2 mRNA CTD PMID:20664735 NCBI chr15:9,112,070...9,155,512
Ensembl chr15:9,112,073...9,155,512
JBrowse link
G Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 increases expression ISO gamma-Linolenic Acid results in increased expression of SLC3A2 mRNA CTD PMID:20664735 NCBI chr19:8,684,931...8,700,733
Ensembl chr19:8,684,246...8,700,733
JBrowse link
G St13 suppression of tumorigenicity 13 increases expression ISO gamma-Linolenic Acid results in increased expression of ST13 mRNA CTD PMID:20664735 NCBI chr15:81,247,869...81,284,278
Ensembl chr15:81,247,870...81,284,278
JBrowse link
G Tff3 trefoil factor 3, intestinal decreases expression ISO gamma-Linolenic Acid results in decreased expression of TFF3 mRNA CTD PMID:20664735 NCBI chr17:31,344,280...31,348,585
Ensembl chr17:31,344,280...31,348,620
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO [gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of TJP1 protein CTD PMID:16514648 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO gamma-Linolenic Acid results in decreased expression of TNF protein CTD PMID:9415022 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO gamma-Linolenic Acid inhibits the reaction [Capsaicin results in increased activity of TRPV1 protein] CTD PMID:17038422 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
JBrowse link
G Txn1 thioredoxin 1 increases expression ISO gamma-Linolenic Acid results in increased expression of TXN mRNA CTD PMID:20664735 NCBI chr 4:57,943,373...57,956,411
Ensembl chr 4:57,943,373...57,956,411
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO gamma-Linolenic Acid results in increased expression of TXNRD1 mRNA CTD PMID:20664735 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546
JBrowse link
linoleamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pparg peroxisome proliferator activated receptor gamma increases activity ISO linoleamide analog results in increased activity of PPARG protein CTD PMID:29288688 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
linoleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP-binding cassette, sub-family A member 1 multiple interactions
decreases expression
increases expression
increases phosphorylation
increases degradation
ISO
EXP
1-Butanol inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]]; Linoleic Acid inhibits the reaction [ABCA1 protein results in increased export of Cholesterol]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]; PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Cholesterol]]; triacsin C inhibits the reaction [Linoleic Acid inhibits the reaction [ABCA1 protein results in increased transport of Phospholipids]]; triacsin C inhibits the reaction [Linoleic Acid results in increased degradation of ABCA1 protein]
Linoleic Acid analog results in decreased expression of ABCA1 mRNA
Linoleic Acid results in increased expression of ABCA1 mRNA
Linoleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA]
Linoleic Acid results in increased phosphorylation of ABCA1 protein
CTD PMID:16118212 PMID:18356535 PMID:27939595 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 decreases expression ISO Linoleic Acid results in decreased expression of ABCG1 mRNA; Linoleic Acid results in decreased expression of ABCG1 protein CTD PMID:16730733 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha decreases expression ISO Linoleic Acid results in decreased expression of ACACA mRNA CTD PMID:14563831 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Acadm acyl-Coenzyme A dehydrogenase, medium chain increases expression ISO Linoleic Acid results in increased expression of ACADM mRNA CTD PMID:23056435 NCBI chr 3:153,627,990...153,650,280
Ensembl chr 3:153,627,994...153,650,269
JBrowse link
G Acly ATP citrate lyase decreases expression ISO Linoleic Acid results in decreased expression of ACLY mRNA CTD PMID:14563831 NCBI chr11:100,367,178...100,418,826
Ensembl chr11:100,367,179...100,418,826
JBrowse link
G Acmsd amino carboxymuconate semialdehyde decarboxylase decreases expression ISO Linoleic Acid results in decreased expression of ACMSD mRNA CTD PMID:18320257 NCBI chr 1:127,657,149...127,695,723
Ensembl chr 1:127,657,150...127,695,715
JBrowse link
G Acox1 acyl-Coenzyme A oxidase 1, palmitoyl increases expression ISO Linoleic Acid results in increased expression of ACOX1 mRNA CTD PMID:18320257 NCBI chr11:116,062,714...116,089,605
Ensembl chr11:116,062,714...116,089,871
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression EXP Linoleic Acid results in decreased expression of ADIPOQ mRNA CTD PMID:17374693 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adipor1 adiponectin receptor 1 increases expression EXP Linoleic Acid analog results in increased expression of ADIPOR1 mRNA CTD PMID:27939595 NCBI chr 1:134,343,116...134,361,089
Ensembl chr 1:134,343,116...134,361,089
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO AGER protein results in increased susceptibility to [Azoxymethane co-treated with Glucose co-treated with Linoleic Acid]; Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]; Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]; Losartan inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Losartan inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Glucose promotes the reaction [Linoleic Acid promotes the reaction [Azoxymethane results in increased expression of AGER protein]]]; Metformin inhibits the reaction [Linoleic Acid promotes the reaction [Glucose promotes the reaction [Azoxymethane results in increased expression of AGER protein]]] CTD PMID:22467055 NCBI chr17:34,816,545...34,819,911
Ensembl chr17:34,816,836...34,819,910
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions ISO Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]] CTD PMID:18001219 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Alox15 arachidonate 15-lipoxygenase increases oxidation ISO ALOX15 protein results in increased oxidation of Linoleic Acid CTD PMID:25786526 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857
JBrowse link
G Apoa1 apolipoprotein A-I multiple interactions ISO Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]; PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]] CTD PMID:16118212 NCBI chr 9:46,139,928...46,141,767
Ensembl chr 9:46,139,878...46,141,764
JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 decreases expression ISO Linoleic Acid results in decreased expression of ASCL2 mRNA CTD PMID:15708366 NCBI chr 7:142,520,559...142,523,001
Ensembl chr 7:142,520,566...142,523,001
JBrowse link
G Bche butyrylcholinesterase increases expression ISO Linoleic Acid results in increased expression of BCHE mRNA CTD PMID:27106529 NCBI chr 3:73,543,138...73,615,767
Ensembl chr 3:73,543,141...73,615,748
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of BCL2 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of BCL2 protein] CTD PMID:22467055 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO Linoleic Acid results in increased expression of CAT protein
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in decreased activity of CAT protein]
CTD PMID:10946007 PMID:34111468 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Linoleic Acid results in increased expression of CCL2 protein CTD PMID:16305726 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CD36 mRNA CTD PMID:28552552 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 multiple interactions ISO Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of CHRNA7 mRNA] CTD PMID:34111468 NCBI chr 7:62,748,440...62,862,274
Ensembl chr 7:62,748,440...62,862,317
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
affects response to substance
EXP CNR1 protein affects the reaction [Linoleic Acid results in increased secretion of GCG protein]
CNR1 protein affects the susceptibility to Linoleic Acid
CTD PMID:30241419 NCBI chr 4:33,923,171...33,948,831
Ensembl chr 4:33,924,593...33,948,831
JBrowse link
G Col1a1 collagen, type I, alpha 1 increases expression EXP Linoleic Acid results in increased expression of COL1A1 mRNA CTD PMID:26240151 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Col3a1 collagen, type III, alpha 1 decreases expression EXP Linoleic Acid results in decreased expression of COL3A1 mRNA CTD PMID:26240151 NCBI chr 1:45,350,698...45,388,866
Ensembl chr 1:45,350,698...45,388,866
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression ISO Linoleic Acid results in increased expression of CPT1A mRNA CTD PMID:11171094 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Crebbp CREB binding protein multiple interactions ISO Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein] CTD PMID:19263263 NCBI chr16:3,899,198...4,031,864
Ensembl chr16:3,899,192...4,031,861
JBrowse link
G Cycs cytochrome c, somatic multiple interactions ISO [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CYCS protein CTD PMID:27016407 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to CYP1A1 promoter]] CTD PMID:18001219 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Linoleic Acid results in decreased activity of CYP1A2 protein CTD PMID:16978661 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 multiple interactions
increases expression
ISO NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 protein]
Linoleic Acid results in increased expression of CYP2A6 mRNA; Linoleic Acid results in increased expression of CYP2A6 protein
CTD PMID:28555106 NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions
decreases activity
ISO CYP2C19 protein results in increased metabolism of [Linoleic Acid co-treated with NADP]
Linoleic Acid results in decreased activity of CYP2C19 protein
CTD PMID:16978661 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions
decreases activity
ISO CYP2C9 protein results in increased metabolism of [Linoleic Acid co-treated with NADP]
Linoleic Acid results in decreased activity of CYP2C9 protein
CTD PMID:16978661 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Linoleic Acid results in decreased activity of CYP2E1 protein CTD PMID:16978661 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP Linoleic Acid analog results in increased expression of DDIT3 protein CTD PMID:27939595 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Dio1 deiodinase, iodothyronine, type I decreases activity ISO Linoleic Acid results in decreased activity of DIO1 protein CTD PMID:30561685 NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
JBrowse link
G Dio2 deiodinase, iodothyronine, type II decreases activity ISO Linoleic Acid results in decreased activity of DIO2 protein CTD PMID:30561685 NCBI chr12:90,691,326...90,705,812
Ensembl chr12:90,691,326...90,705,812
JBrowse link
G Dio3 deiodinase, iodothyronine type III decreases activity ISO Linoleic Acid results in decreased activity of DIO3 protein CTD PMID:30561685 NCBI chr12:110,245,664...110,247,531
Ensembl chr12:110,245,502...110,247,531
JBrowse link
G Edn1 endothelin 1 decreases expression ISO Linoleic Acid results in decreased expression of EDN1 mRNA; Linoleic Acid results in decreased expression of EDN1 protein CTD PMID:16895544 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Fabp1 fatty acid binding protein 1, liver decreases expression ISO Linoleic Acid results in decreased expression of FABP1 mRNA CTD PMID:15708366 NCBI chr 6:71,176,863...71,182,018
Ensembl chr 6:71,176,811...71,182,007
JBrowse link
G Fabp3 fatty acid binding protein 3, muscle and heart decreases expression ISO Linoleic Acid results in decreased expression of FABP3 mRNA CTD PMID:15708366 NCBI chr 4:130,202,531...130,209,256
Ensembl chr 4:130,202,388...130,209,256
JBrowse link
G Fabp4 fatty acid binding protein 4, adipocyte affects localization EXP Linoleic Acid analog affects the localization of FABP4 protein CTD PMID:27939595 NCBI chr 3:10,269,406...10,273,653
Ensembl chr 3:10,269,148...10,273,636
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions
increases expression
ISO
EXP
[Linoleic Acid co-treated with Testosterone] results in increased expression of FADS2 mRNA
FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein]
Linoleic Acid results in increased expression of FADS2 mRNA; Linoleic Acid results in increased expression of FADS2 protein
CTD PMID:21457203 PMID:26240151 NCBI chr19:10,040,129...10,078,867
Ensembl chr19:10,040,129...10,079,110
JBrowse link
G Fasn fatty acid synthase decreases expression ISO Linoleic Acid results in decreased expression of FASN mRNA CTD PMID:14563831 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Ffar3 free fatty acid receptor 3 increases expression EXP Linoleic Acid analog results in increased expression of FFAR3 mRNA CTD PMID:27939595 NCBI chr 7:30,553,755...30,555,603
Ensembl chr 7:30,553,755...30,555,603
JBrowse link
G Foxo1 forkhead box O1 decreases expression EXP Linoleic Acid results in decreased expression of FOXO1 protein CTD PMID:17374693 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Gcg glucagon multiple interactions EXP CNR1 protein affects the reaction [Linoleic Acid results in increased secretion of GCG protein] CTD PMID:30241419 NCBI chr 2:62,304,874...62,313,997
Ensembl chr 2:62,304,874...62,313,994
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit increases expression ISO Linoleic Acid metabolite results in increased expression of GCLM mRNA CTD PMID:26879219 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Gjb1 gap junction protein, beta 1 increases abundance EXP GJB1 protein results in increased abundance of Linoleic Acid CTD PMID:27859493 NCBI chr  X:100,419,982...100,429,235
Ensembl chr  X:100,419,984...100,429,235
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) multiple interactions ISO Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of GRIN2A mRNA] CTD PMID:34111468 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424
JBrowse link
G Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) multiple interactions ISO Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of GRIN2B mRNA] CTD PMID:34111468 NCBI chr 6:135,690,219...136,150,658
Ensembl chr 6:135,690,231...136,150,509
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases secretion ISO Linoleic Acid results in increased secretion of HAVCR1 protein CTD PMID:31686351 NCBI chr11:46,630,644...46,670,405
Ensembl chr11:46,625,907...46,670,405
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO
EXP
NFE2L2 mRNA promotes the reaction [Linoleic Acid metabolite results in increased expression of HMOX1 mRNA]
Linoleic Acid metabolite results in increased expression of HMOX1 mRNA; Linoleic Acid metabolite results in increased expression of HMOX1 protein
CTD PMID:26879219 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hspa5 heat shock protein 5 increases expression EXP Linoleic Acid analog results in increased expression of HSPA5 protein CTD PMID:27939595 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Ifng interferon gamma increases expression ISO Linoleic Acid results in increased expression of IFNG protein CTD PMID:16305726 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Il10 interleukin 10 increases expression ISO Linoleic Acid results in increased expression of IL10 protein CTD PMID:16305726 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
ISO Linoleic Acid results in increased expression of IL1B protein
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of IL1B mRNA]
CTD PMID:16305726 PMID:34111468 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 decreases expression ISO Linoleic Acid results in decreased expression of IL2 protein CTD PMID:16305726 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il4 interleukin 4 decreases expression ISO Linoleic Acid results in decreased expression of IL4 protein CTD PMID:16305726 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 decreases expression ISO Linoleic Acid results in decreased expression of IL5 protein CTD PMID:16305726 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 affects expression
multiple interactions
increases expression
increases secretion
ISO
EXP
Linoleic Acid affects the expression of IL6 protein
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of IL6 mRNA]
Linoleic Acid results in increased expression of IL6 mRNA
Linoleic Acid results in increased secretion of IL6 protein
CTD PMID:16305726 PMID:17374693 PMID:21457203 PMID:34111468 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Insr insulin receptor increases expression EXP Linoleic Acid analog results in increased expression of INSR mRNA CTD PMID:27939595 NCBI chr 8:3,200,922...3,329,649
Ensembl chr 8:3,172,061...3,329,617
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO Linoleic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr10:3,490,274...3,504,880
Ensembl chr10:3,490,240...3,504,877
JBrowse link
G Lcat lecithin cholesterol acyltransferase increases expression EXP Linoleic Acid analog results in increased expression of LCAT mRNA CTD PMID:27939595 NCBI chr 8:106,666,183...106,670,034
Ensembl chr 8:106,666,183...106,670,014
JBrowse link
G Lipc lipase, hepatic multiple interactions EXP [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Linoleic Acid CTD PMID:24777581 NCBI chr 9:70,705,410...70,859,503
Ensembl chr 9:70,705,410...70,859,508
JBrowse link
G Lipg lipase, endothelial multiple interactions EXP [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Linoleic Acid CTD PMID:24777581 NCBI chr18:75,072,393...75,095,380
Ensembl chr18:75,072,393...75,094,334
JBrowse link
G Lox lysyl oxidase multiple interactions
increases activity
EXP FADS2 protein inhibits the reaction [Linoleic Acid results in increased activity of LOX protein]; TGFB1 protein promotes the reaction [Linoleic Acid results in increased activity of LOX protein] CTD PMID:26240151 NCBI chr18:52,649,132...52,662,939
Ensembl chr18:52,649,139...52,662,939
JBrowse link
G Lpin1 lipin 1 decreases expression EXP Linoleic Acid analog results in decreased expression of LPIN1 mRNA CTD PMID:27939595 NCBI chr12:16,585,670...16,697,020
Ensembl chr12:16,585,670...16,696,967
JBrowse link
G Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) increases expression ISO Linoleic Acid results in increased expression of LRAT mRNA CTD PMID:12576510 NCBI chr 3:82,799,889...82,811,281
Ensembl chr 3:82,799,886...82,811,280
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO Linoleic Acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:23288142 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO Linoleic Acid results in decreased expression of and results in decreased activity of MMP9 protein
[Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of MMP9 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of MMP9 protein]
Linoleic Acid results in decreased expression of MMP9 mRNA
CTD PMID:22467055 PMID:23288142 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO Linoleic Acid affects the reaction [Zymosan analog affects the localization of NCF1 protein] CTD PMID:12101222 NCBI chr 5:134,248,907...134,258,479
Ensembl chr 5:134,248,907...134,258,479
JBrowse link
G Ncf2 neutrophil cytosolic factor 2 multiple interactions ISO Linoleic Acid affects the reaction [Zymosan analog affects the localization of NCF2 protein] CTD PMID:12101222 NCBI chr 1:152,675,904...152,712,743
Ensembl chr 1:152,675,945...152,712,742
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Linoleic Acid promotes the reaction [PPARA protein binds to NCOA1 protein] CTD PMID:19263263 NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO Linoleic Acid promotes the reaction [PPARA protein binds to NCOA2 protein] CTD PMID:19263263 NCBI chr 1:13,209,329...13,444,451
Ensembl chr 1:13,209,329...13,444,307
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases expression
multiple interactions
ISO
EXP
Linoleic Acid metabolite results in increased expression of NFE2L2 protein; Linoleic Acid results in increased expression of NFE2L2 mRNA; Linoleic Acid results in increased expression of NFE2L2 protein
NFE2L2 mRNA promotes the reaction [Linoleic Acid metabolite results in increased expression of HMOX1 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 mRNA]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of CYP2A6 protein]; NFE2L2 protein promotes the reaction [Linoleic Acid results in increased expression of GSTA1 mRNA]
CTD PMID:26879219 PMID:28555106 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions ISO Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of NFKB1 mRNA] CTD PMID:34111468 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of NOS2 protein]; Linoleic Acid affects the reaction [Azoxymethane affects the expression of NOS2 protein] CTD PMID:22467055 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nos3 nitric oxide synthase 3, endothelial cell decreases expression ISO Linoleic Acid results in decreased expression of NOS3 mRNA CTD PMID:16895544 NCBI chr 5:24,569,772...24,589,472
Ensembl chr 5:24,569,808...24,589,472
JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases expression ISO
EXP
Linoleic Acid metabolite results in increased expression of NQO1 mRNA CTD PMID:26879219 NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838
JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 multiple interactions EXP [NR5A2 gene mutant form results in increased susceptibility to Dietary Fats] which results in increased abundance of Linoleic Acid analog CTD PMID:29515023 NCBI chr 1:136,770,300...136,888,186
Ensembl chr 1:136,770,309...136,888,186
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions EXP [Glucose deficiency co-treated with Linoleic Acid] results in increased expression of PCK1 mRNA CTD PMID:8536680 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 increases expression ISO Linoleic Acid results in increased expression of PDK4 mRNA CTD PMID:23056435 NCBI chr 6:5,483,351...5,496,278
Ensembl chr 6:5,483,351...5,496,309
JBrowse link
G Pld2 phospholipase D2 multiple interactions ISO PLD2 protein inhibits the reaction [Linoleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased export of Cholesterol]]] CTD PMID:16118212 NCBI chr11:70,430,318...70,448,936
Ensembl chr11:70,430,890...70,448,936
JBrowse link
G Plin1 perilipin 1 increases expression EXP Linoleic Acid analog results in increased expression of PLIN1 mRNA CTD PMID:27939595 NCBI chr 7:79,370,912...79,382,652
Ensembl chr 7:79,369,966...79,382,651
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
ISO Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]; Linoleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of phenylacetic acid]
Linoleic Acid results in decreased activity of PON1 protein
CTD PMID:12871208 PMID:15375178 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
increases expression
affects abundance
increases activity
affects binding
ISO
EXP
[Bezafibrate binds to and results in increased activity of PPARA protein] which results in increased oxidation of Linoleic Acid; Linoleic Acid affects the reaction [PPARA protein binds to CREBBP protein]; Linoleic Acid binds to and results in increased activity of PPARA protein; Linoleic Acid promotes the reaction [PPARA protein binds to NCOA1 protein]; Linoleic Acid promotes the reaction [PPARA protein binds to NCOA2 protein]
Linoleic Acid results in increased expression of PPARA mRNA
PPARA protein affects the abundance of Linoleic Acid
Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Linoleic Acid]; Linoleic Acid binds to and results in increased activity of PPARA protein
Linoleic Acid results in increased expression of PPARA mRNA; Linoleic Acid results in increased expression of PPARA protein
Linoleic Acid results in increased activity of PPARA protein
Linoleic Acid binds to PPARA protein
CTD PMID:10403814 PMID:11172467 PMID:15491415 PMID:16731579 PMID:18154422 More... NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Ppard peroxisome proliferator activator receptor delta multiple interactions
decreases expression
affects binding
increases expression
increases activity
EXP
ISO
Linoleic Acid binds to and results in increased activity of PPARB protein
Linoleic Acid results in decreased expression of PPARD mRNA
Linoleic Acid binds to PPARB protein
Linoleic Acid results in increased expression of PPARD mRNA
Linoleic Acid results in increased activity of PPARD protein
CTD PMID:11172467 PMID:15708366 PMID:16731579 PMID:23843199 PMID:25786526 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma affects binding
multiple interactions
increases expression
increases activity
decreases expression
ISO
EXP
Linoleic Acid binds to PPARG protein
Linoleic Acid binds to and results in increased activity of PPARG protein
Linoleic Acid results in increased expression of PPARG mRNA
resveratrol inhibits the reaction [Linoleic Acid results in increased expression of PPARG protein]
Linoleic Acid results in increased activity of PPARG protein
Linoleic Acid results in decreased expression of PPARG mRNA; Linoleic Acid results in decreased expression of PPARG protein
CTD PMID:11172467 PMID:12021203 PMID:15708366 PMID:16731579 PMID:18154422 More... NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression ISO Linoleic Acid results in increased expression of PPARGC1A mRNA CTD PMID:23056435 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta increases expression ISO Linoleic Acid results in increased expression of PPARGC1B mRNA CTD PMID:23056435 NCBI chr18:61,424,516...61,533,846
Ensembl chr18:61,431,207...61,533,502
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO Linoleic Acid results in increased expression of PTGS2 mRNA
Linoleic Acid inhibits the reaction [Benzo(a)pyrene results in increased expression of PTGS2 mRNA]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PTGS2 promoter]]; Linoleic Acid inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of PTGS2 mRNA]
CTD PMID:14563831 PMID:18001219 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rxra retinoid X receptor alpha affects binding
multiple interactions
ISO Linoleic Acid binds to RXRA protein
Linoleic Acid binds to and results in increased activity of RXRA protein
CTD PMID:16258897 PMID:16731579 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Scd2 stearoyl-Coenzyme A desaturase 2 increases expression
multiple interactions
ISO Linoleic Acid results in increased expression of SCD mRNA; Linoleic Acid results in increased expression of SCD protein
[Linoleic Acid co-treated with Testosterone] results in increased expression of SCD mRNA
CTD PMID:21457203 NCBI chr19:44,282,115...44,295,303
Ensembl chr19:44,282,113...44,295,303
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 increases expression EXP Linoleic Acid results in increased expression of SERPINE1 mRNA CTD PMID:17374693 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Slc22a6 solute carrier family 22 (organic anion transporter), member 6 decreases activity ISO Linoleic Acid results in decreased activity of SLC22A6 protein CTD PMID:29045746 NCBI chr19:8,595,360...8,605,663
Ensembl chr19:8,595,403...8,605,663
JBrowse link
G Slc22a8 solute carrier family 22 (organic anion transporter), member 8 decreases activity ISO Linoleic Acid results in decreased activity of SLC22A8 protein CTD PMID:29045746 NCBI chr19:8,568,576...8,589,199
Ensembl chr19:8,568,618...8,589,199
JBrowse link
G Smad3 SMAD family member 3 decreases abundance EXP SMAD3 protein results in decreased abundance of Linoleic Acid CTD PMID:23034213 NCBI chr 9:63,554,048...63,665,276
Ensembl chr 9:63,554,049...63,665,276
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression ISO Linoleic Acid results in decreased expression of SREBF1 mRNA CTD PMID:14563831 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP TGFB1 protein promotes the reaction [Linoleic Acid results in increased activity of LOX protein] CTD PMID:26240151 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor decreases response to substance
multiple interactions
ISO Linoleic Acid results in decreased susceptibility to TNF protein
Linoleic Acid inhibits the reaction [amyloid beta-protein (1-42) results in increased expression of TNF mRNA]
CTD PMID:22683933 PMID:34111468 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions EXP TRPV1 results in increased susceptibility to [Linoleic Acid co-treated with Freund's Adjuvant] CTD PMID:23006841 NCBI chr11:73,124,975...73,152,148
Ensembl chr11:73,125,118...73,152,068
JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) increases expression ISO Linoleic Acid results in increased expression of UCP2 mRNA CTD PMID:11341955 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [Linoleic Acid co-treated with Glucose] affects the reaction [Azoxymethane affects the expression of VEGFA protein] CTD PMID:22467055 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Wnt10b wingless-type MMTV integration site family, member 10B decreases expression EXP Linoleic Acid results in decreased expression of WNT10B mRNA CTD PMID:12021203 NCBI chr15:98,668,593...98,676,093
Ensembl chr15:98,668,593...98,676,031
JBrowse link
linoleic acid hydroperoxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen multiple interactions
increases lipidation
ISO Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form] CTD PMID:26111765 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Cygb cytoglobin increases metabolic processing ISO CYGB protein results in increased metabolism of linoleic acid hydroperoxide CTD PMID:11320098 NCBI chr11:116,536,421...116,544,887
Ensembl chr11:116,536,421...116,545,139
JBrowse link
G Gpx1 glutathione peroxidase 1 increases reduction ISO GPX1 protein results in increased reduction of linoleic acid hydroperoxide CTD PMID:8428933 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gpx2 glutathione peroxidase 2 increases reduction ISO GPX2 protein results in increased reduction of linoleic acid hydroperoxide CTD PMID:8428933 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
lipoxin A4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions EXP lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of ACTA2 mRNA]; lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of ACTA2 protein] CTD PMID:34537180 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Agt angiotensinogen multiple interactions EXP 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of AGT protein alternative form]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of AGT protein alternative form]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of AGT protein alternative form]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of AGT protein alternative form] CTD PMID:29969931 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions EXP AHR affects the reaction [lipoxin A4 results in increased expression of SOCS2 mRNA] CTD PMID:16415877 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Alox5 arachidonate 5-lipoxygenase multiple interactions
affects abundance
ISO zileuton inhibits the reaction [ALOX5 protein affects the abundance of lipoxin A4] CTD PMID:15326064 NCBI chr 6:116,387,030...116,438,139
Ensembl chr 6:116,387,038...116,438,139
JBrowse link
G Bax BCL2-associated X protein multiple interactions ISO lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of BAX protein] CTD PMID:23063943 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO lipoxin A4 inhibits the reaction [Lipopolysaccharides results in decreased expression of BCL2 protein] CTD PMID:23063943 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
ISO Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of CASP3 protein] CTD PMID:36057361 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions EXP lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of COL1A1 mRNA] CTD PMID:34537180 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Col1a2 collagen, type I, alpha 2 multiple interactions EXP lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of COL1A2 protein] CTD PMID:34537180 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
decreases expression
ISO lipoxin A4 analog inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; lipoxin A4 analog inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]; lipoxin A4 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of CXCL8 protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL8 mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of CXCL8 protein]
lipoxin A4 analog results in decreased expression of CXCL8 protein
CTD PMID:12235371 PMID:21659618 PMID:23063943 PMID:27663891 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions EXP lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of CXCL2 protein] CTD PMID:10377187 NCBI chr 5:91,051,758...91,053,797
Ensembl chr 5:91,051,730...91,053,797
JBrowse link
G Fpr2 formyl peptide receptor 2 multiple interactions
increases activity
ISO [Aspirin results in increased abundance of lipoxin A4] which results in increased expression of FPR2; lipoxin A4 analog binds to and results in decreased activity of FPR2 protein
lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of FPR2 mRNA]
lipoxin A4 results in increased activity of FPR2
CTD PMID:12594298 PMID:19597002 PMID:21765620 NCBI chr17:18,108,086...18,114,214
Ensembl chr17:18,108,086...18,114,214
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO lipoxin A4 results in increased expression of HMOX1 mRNA; lipoxin A4 results in increased expression of HMOX1 protein
lipoxin A4 promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]
CTD PMID:23826208 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Icam1 intercellular adhesion molecule 1 affects response to substance
multiple interactions
increases expression
ISO ICAM1 protein affects the susceptibility to lipoxin A4
Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of ICAM1 protein]
CTD PMID:7602232 PMID:36057361 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Il10 interleukin 10 multiple interactions EXP 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein]]; lipoxin A4 promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL10 protein] CTD PMID:29969931 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 multiple interactions EXP lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of IL13 protein] CTD PMID:34537180 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
decreases secretion
ISO
EXP
lipoxin A4 analog results in decreased expression of IL1B protein
2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]
lipoxin A4 analog results in decreased secretion of IL1B protein
lipoxin A4 analog inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; lipoxin A4 inhibits the reaction [TNF protein results in increased secretion of IL1B protein]
CTD PMID:10377187 PMID:21659618 PMID:21831303 PMID:29969931 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il4 interleukin 4 increases secretion
multiple interactions
EXP lipoxin A4 analog results in increased secretion of IL4 protein
lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of IL4 protein]
CTD PMID:10377187 PMID:34537180 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il5 interleukin 5 multiple interactions EXP lipoxin A4 inhibits the reaction [Ovalbumin results in increased expression of IL5 protein] CTD PMID:34537180 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Il6 interleukin 6 multiple interactions ISO lipoxin A4 inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased secretion of IL6 protein] CTD PMID:27663891 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions EXP lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein] CTD PMID:21831303 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions EXP lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein] CTD PMID:21831303 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 increases phosphorylation
multiple interactions
ISO lipoxin A4 results in increased phosphorylation of MAPK9 protein
Gentamicins inhibits the reaction [lipoxin A4 results in increased phosphorylation of MAPK9 protein]
CTD PMID:36057361 NCBI chr11:49,737,558...49,777,248
Ensembl chr11:49,737,578...49,777,248
JBrowse link
G Mas1 MAS1 oncogene multiple interactions EXP 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [[lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAS1 mRNA]; 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of MAS1 protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [[lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAS1 mRNA]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of MAS1 protein]]; [lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAS1 mRNA; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [[lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of MAS1 mRNA]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of MAS1 protein]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of MAS1 protein] CTD PMID:29969931 NCBI chr17:13,056,981...13,087,037
Ensembl chr17:13,059,966...13,087,030
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased activity of MPO protein] CTD PMID:29969931 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects localization
multiple interactions
ISO lipoxin A4 affects the localization of NFE2L2 protein
lipoxin A4 promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]
CTD PMID:23826208 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions EXP 2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased degradation of NFKBIA protein] CTD PMID:21831303 PMID:29969931 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions EXP butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:21831303 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Pdgfb platelet derived growth factor, B polypeptide multiple interactions ISO lipoxin A4 affects the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]; PDGFB protein promotes the reaction [lipoxin A4 results in decreased phosphorylation of PDGFRB protein] CTD PMID:12223454 PMID:20709806 NCBI chr15:79,880,066...79,899,178
Ensembl chr15:79,880,075...79,899,178
JBrowse link
G Pdgfrb platelet derived growth factor receptor, beta polypeptide multiple interactions
decreases phosphorylation
ISO lipoxin A4 affects the reaction [PDGFB protein results in increased phosphorylation of PDGFRB protein]; lipoxin A4 inhibits the reaction [Leukotriene D4 results in increased activity of PDGFRB protein]; PDGFB protein promotes the reaction [lipoxin A4 results in decreased phosphorylation of PDGFRB protein] CTD PMID:12223454 PMID:20709806 NCBI chr18:61,178,194...61,218,139
Ensembl chr18:61,178,222...61,218,133
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions ISO lipoxin A4 binds to and results in increased activity of PPARG protein CTD PMID:19321784 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions ISO [WEB 2086 binds to and results in decreased activity of PTAFR protein] which results in decreased susceptibility to lipoxin A4 CTD PMID:7602232 NCBI chr 4:132,291,378...132,309,994
Ensembl chr 4:132,291,378...132,309,994
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
affects abundance
ISO [lipoxin A4 co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of PTGS2 protein; Celecoxib inhibits the reaction [PTGS2 protein affects the abundance of lipoxin A4]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein] CTD PMID:15326064 PMID:21765620 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO
EXP
lipoxin A4 inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein]]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of and affects the localization of RELA protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased localization of RELA protein]
CTD PMID:21831303 PMID:23063943 PMID:29969931 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Selp selectin, platelet affects response to substance ISO SELP protein affects the susceptibility to lipoxin A4 CTD PMID:7602232 NCBI chr 1:163,942,833...163,977,595
Ensembl chr 1:163,942,833...163,977,595
JBrowse link
G Socs2 suppressor of cytokine signaling 2 multiple interactions
increases expression
EXP AHR affects the reaction [lipoxin A4 results in increased expression of SOCS2 mRNA]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 results in increased expression of SOCS2 mRNA]
lipoxin A4 results in increased expression of SOCS2 mRNA; lipoxin A4 results in increased expression of SOCS2 protein
CTD PMID:16415877 NCBI chr10:95,219,765...95,253,176
Ensembl chr10:95,221,224...95,253,042
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP lipoxin A4 inhibits the reaction [Ovalbumin results in increased phosphorylation of STAT3 protein] CTD PMID:34537180 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
ISO Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of TGFB1 protein] CTD PMID:36057361 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO
EXP
lipoxin A4 analog inhibits the reaction [TNF protein results in increased expression of IL1B mRNA]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; lipoxin A4 inhibits the reaction [TNF protein results in increased secretion of IL1B protein]
Gentamicins inhibits the reaction [lipoxin A4 results in increased expression of TNF protein]
2-(1-carboxy-2-(3-(3,5-dichlorobenzyl)-3H-imidazol-4-yl)ethylamino)-4-methylpentanoic acid inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; 7-Ala-angiotensin (1-7) inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanine inhibits the reaction [lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of CXCL2 protein]; lipoxin A4 analog inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; lipoxin A4 inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; lipoxin A4 inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:10377187 PMID:21575454 PMID:21831303 PMID:23063943 PMID:29969931 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
methyl linoleate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO methyl linoleate inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr10:3,490,274...3,504,880
Ensembl chr10:3,490,240...3,504,877
JBrowse link
soybean oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 affects expression ISO Soybean Oil affects the expression of ABCB11 mRNA CTD PMID:15770074 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects expression ISO Soybean Oil affects the expression of ABCB1B mRNA CTD PMID:15770074 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 affects expression ISO Soybean Oil affects the expression of ABCB4 mRNA CTD PMID:15770074 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 affects expression ISO Soybean Oil affects the expression of ABCC1 mRNA CTD PMID:15770074 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 affects expression ISO Soybean Oil affects the expression of ABCC2 mRNA CTD PMID:15770074 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 affects expression ISO Soybean Oil affects the expression of ABCC5 mRNA CTD PMID:15770074 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 affects expression ISO Soybean Oil affects the expression of ABCC6 mRNA CTD PMID:15770074 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726
JBrowse link
G Acat1 acetyl-Coenzyme A acetyltransferase 1 decreases activity ISO Soybean Oil results in decreased activity of ACAT1 protein CTD PMID:12559476 NCBI chr 9:53,491,822...53,521,650
Ensembl chr 9:53,491,822...53,521,682
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression ISO Soybean Oil results in increased expression of BCL2 protein CTD PMID:15309441 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Cat catalase increases activity ISO Soybean Oil results in increased activity of CAT protein CTD PMID:12781854 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO Soybean Oil results in increased expression of CCND1 mRNA CTD PMID:21088903 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Cyp4a12b cytochrome P450, family 4, subfamily a, polypeptide 12B affects expression ISO Soybean Oil affects the expression of CYP4A1 mRNA CTD PMID:16079505 NCBI chr 4:115,268,821...115,296,231
Ensembl chr 4:115,268,821...115,296,231
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 increases activity ISO Soybean Oil results in increased activity of CYP7A1 protein CTD PMID:12559476 NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein] CTD PMID:11600134 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase increases activity ISO Soybean Oil results in increased activity of HMGCR protein CTD PMID:12559476 NCBI chr13:96,785,470...96,807,444
Ensembl chr13:96,785,475...96,807,444
JBrowse link
G Il12b interleukin 12b decreases expression EXP Soybean Oil results in decreased expression of IL12B mRNA CTD PMID:10065739 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 affects expression ISO Soybean Oil affects the expression of SLC22A1 mRNA CTD PMID:15770074 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 affects expression ISO Soybean Oil affects the expression of SLC22A7 mRNA CTD PMID:15770074 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    chemical entity 22208
      atom 22170
        nonmetal atom 22055
          carbon atom 21859
            organic molecular entity 21830
              lipid 18859
                fatty acid 17131
                  unsaturated fatty acid 1091
                    polyunsaturated fatty acid 832
                      omega-6 fatty acid 553
                        (10Z,13Z,16Z)-docosatrienoic acid + 0
                        (10Z,13Z,16Z,19Z,22Z)-octacosapentaenoic acid + 0
                        (11Z,14Z,17Z,20Z)-hexacosatetraenoic acid + 0
                        (12Z,15Z,18Z,21Z,24Z)-triacontapentaenoic acid + 0
                        (13Z,16Z,19Z,22Z)-octacosatetraenoic acid + 0
                        (14Z,17Z,20Z,23Z,26Z)-dotriacontapentaenoic acid + 0
                        (15Z,18Z,21Z,24Z)-triacontatetraenoic acid + 0
                        (16Z,19Z,22Z,25Z,28Z)-tetratriacontapentaenoic acid + 0
                        (17Z,20Z,23Z,26Z)-dotriacontatetraenoic acid + 0
                        (18Z,21Z,24Z,27Z,30Z)-hexatriacontapentaenoic acid + 0
                        (19Z,22Z,25Z,28Z)-tetratriacontatetraenoic acid + 0
                        (20Z,23Z,26Z,29Z,32Z)-octatriacontapentaenoic acid + 0
                        (21Z,24Z,27Z,30Z)-hexatriacontatetraenoic acid + 0
                        (23Z,26Z,29Z,32Z)-octatriacontatetraenoic acid + 0
                        (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid + 4
                        (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoic acid + 0
                        (8E,10E,12Z)-octadecatrienoic acid + 0
                        (8Z,11Z,14Z,17Z,20Z)-hexacosapentaenoic acid + 0
                        (9Z,12Z,15Z,18Z)-tetracosatetraenoic acid + 0
                        all-cis-docosa-7,10,13,16-tetraenoic acid + 2
                        arachidonic acid + 318
                        cis-4-decenoic acid + 0
                        fatty acid 18:3-omega-3omega-6 0
                        fatty acid 20:3-omega-3omega-6 0
                        fatty acid 20:4-omega-6 0
                        fatty acid 22:5-omega-6 0
                        gamma-linolenic acid + 41
                        linoelaidic acid 0
                        linoleic acid + 275
                        lysophosphatidylcholine 0:0/20:3-omega-3omega-6 0
                        lysophosphatidylcholine 18:3-omega-3omega-6 + 0
                        lysophosphatidylcholine 18:3-omega-3omega-6/0:0 0
                        lysophosphatidylcholine 20:3-omega-3omega-6 + 0
                        lysophosphatidylcholine 20:3-omega-3omega-6/0:0 0
                        lysophosphatidylcholine 22:5-omega-6 0
                        lysophosphatidylcholine 22:5-omega-6/0:0 0
                        lysophosphatidylethanolamine 20:3-omega-3omega-6 0
                        lysophosphatidylethanolamine 22:5-omega-6 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            heteroorganic entity 21482
                              organochalcogen compound 20966
                                organooxygen compound 20806
                                  carbon oxoacid 19593
                                    carboxylic acid 19589
                                      monocarboxylic acid 18952
                                        fatty acid 17131
                                          unsaturated fatty acid 1091
                                            polyunsaturated fatty acid 832
                                              essential fatty acid 560
                                                omega-6 fatty acid 553
                                                  (10Z,13Z,16Z)-docosatrienoic acid + 0
                                                  (10Z,13Z,16Z,19Z,22Z)-octacosapentaenoic acid + 0
                                                  (11Z,14Z,17Z,20Z)-hexacosatetraenoic acid + 0
                                                  (12Z,15Z,18Z,21Z,24Z)-triacontapentaenoic acid + 0
                                                  (13Z,16Z,19Z,22Z)-octacosatetraenoic acid + 0
                                                  (14Z,17Z,20Z,23Z,26Z)-dotriacontapentaenoic acid + 0
                                                  (15Z,18Z,21Z,24Z)-triacontatetraenoic acid + 0
                                                  (16Z,19Z,22Z,25Z,28Z)-tetratriacontapentaenoic acid + 0
                                                  (17Z,20Z,23Z,26Z)-dotriacontatetraenoic acid + 0
                                                  (18Z,21Z,24Z,27Z,30Z)-hexatriacontapentaenoic acid + 0
                                                  (19Z,22Z,25Z,28Z)-tetratriacontatetraenoic acid + 0
                                                  (20Z,23Z,26Z,29Z,32Z)-octatriacontapentaenoic acid + 0
                                                  (21Z,24Z,27Z,30Z)-hexatriacontatetraenoic acid + 0
                                                  (23Z,26Z,29Z,32Z)-octatriacontatetraenoic acid + 0
                                                  (4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid + 4
                                                  (6Z,9Z,12Z,15Z,18Z)-tetracosapentaenoic acid + 0
                                                  (8E,10E,12Z)-octadecatrienoic acid + 0
                                                  (8Z,11Z,14Z,17Z,20Z)-hexacosapentaenoic acid + 0
                                                  (9Z,12Z,15Z,18Z)-tetracosatetraenoic acid + 0
                                                  all-cis-docosa-7,10,13,16-tetraenoic acid + 2
                                                  arachidonic acid + 318
                                                  cis-4-decenoic acid + 0
                                                  fatty acid 18:3-omega-3omega-6 0
                                                  fatty acid 20:3-omega-3omega-6 0
                                                  fatty acid 20:4-omega-6 0
                                                  fatty acid 22:5-omega-6 0
                                                  gamma-linolenic acid + 41
                                                  linoelaidic acid 0
                                                  linoleic acid + 275
                                                  lysophosphatidylcholine 0:0/20:3-omega-3omega-6 0
                                                  lysophosphatidylcholine 18:3-omega-3omega-6 + 0
                                                  lysophosphatidylcholine 18:3-omega-3omega-6/0:0 0
                                                  lysophosphatidylcholine 20:3-omega-3omega-6 + 0
                                                  lysophosphatidylcholine 20:3-omega-3omega-6/0:0 0
                                                  lysophosphatidylcholine 22:5-omega-6 0
                                                  lysophosphatidylcholine 22:5-omega-6/0:0 0
                                                  lysophosphatidylethanolamine 20:3-omega-3omega-6 0
                                                  lysophosphatidylethanolamine 22:5-omega-6 0
paths to the root