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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-hydroxy monocarboxylic acid
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Accession:CHEBI:35970 term browser browse the term
Definition:A hydroxy monocarboxylic acid which has hydroxy group located gamma to the carboxy group.
Synonyms:related_synonym: 4-hydroxy monocarboxylic acids;   gamma-hydroxy monocarboxylic acid;   gamma-hydroxy monocarboxylic acids


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4-hydroxybutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases abundance ISO ALDH5A1 mutant form results in increased abundance of 4-hydroxybutyric acid
ALDH5A1 gene mutant form results in increased abundance of 4-hydroxybutyric acid
CTD PMID:17438226 PMID:29031482 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Gh1 growth hormone 1 multiple interactions
increases secretion
ISO Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein] CTD PMID:10657535 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      molecular entity 19771
        polyatomic entity 19689
          heteroatomic molecular entity 19619
            hydroxides 19080
              organic hydroxy compound 18659
                hydroxy carboxylic acid 3615
                  4-hydroxy carboxylic acid 2
                    4-hydroxy monocarboxylic acid 2
                      (4R)-4-hydroxypentanoic acid + 0
                      2-dehydro-3-deoxy-D-arabinonic acid 0
                      3-dehydroquinic acid 0
                      3-dehydroshikimic acid 0
                      4-hydroxy-2-oxohexanoic acid + 0
                      4-hydroxy-2-oxopentanoic acid + 0
                      4-hydroxybutyric acid + 2
                      4-hydroxylauric acid + 0
                      5-chloro-4-hydroxy-2-oxopentanoic acid 0
                      TX-1875 0
                      trans-4-hydroxycyclohexanecarboxylic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic group 18603
                              organic divalent group 18594
                                organodiyl group 18594
                                  carbonyl group 18507
                                    carbonyl compound 18507
                                      carboxylic acid 18159
                                        hydroxy carboxylic acid 3615
                                          4-hydroxy carboxylic acid 2
                                            4-hydroxy monocarboxylic acid 2
                                              (4R)-4-hydroxypentanoic acid + 0
                                              2-dehydro-3-deoxy-D-arabinonic acid 0
                                              3-dehydroquinic acid 0
                                              3-dehydroshikimic acid 0
                                              4-hydroxy-2-oxohexanoic acid + 0
                                              4-hydroxy-2-oxopentanoic acid + 0
                                              4-hydroxybutyric acid + 2
                                              4-hydroxylauric acid + 0
                                              5-chloro-4-hydroxy-2-oxopentanoic acid 0
                                              TX-1875 0
                                              trans-4-hydroxycyclohexanecarboxylic acid 0
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