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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4-hydroxy monocarboxylic acid
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Accession:CHEBI:35970 term browser browse the term
Definition:A hydroxy monocarboxylic acid which has hydroxy group located gamma to the carboxy group.
Synonyms:related_synonym: 4-hydroxy monocarboxylic acids;   gamma-hydroxy monocarboxylic acid;   gamma-hydroxy monocarboxylic acids



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4-hydroxybutyric acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 increases abundance ISO ALDH5A1 mutant form results in increased abundance of 4-hydroxybutyric acid
ALDH5A1 gene mutant form results in increased abundance of 4-hydroxybutyric acid
CTD PMID:17438226 PMID:29031482 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677
JBrowse link
G Gh1 growth hormone 1 multiple interactions
increases secretion
ISO Cocaine inhibits the reaction [4-hydroxybutyric acid results in increased secretion of GH1 protein] CTD PMID:10657535 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    chemical entity 19800
      molecular entity 19799
        polyatomic entity 19721
          heteroatomic molecular entity 19662
            hydroxides 19158
              organic hydroxy compound 18656
                hydroxy carboxylic acid 3656
                  4-hydroxy carboxylic acid 2
                    4-hydroxy monocarboxylic acid 2
                      (4R)-4-hydroxypentanoic acid + 0
                      2-dehydro-3-deoxy-D-arabinonic acid 0
                      3-dehydroquinic acid 0
                      3-dehydroshikimic acid 0
                      4-hydroxy-2-oxohexanoic acid + 0
                      4-hydroxy-2-oxopentanoic acid + 0
                      4-hydroxybutyric acid + 2
                      4-hydroxylauric acid + 0
                      5-chloro-4-hydroxy-2-oxopentanoic acid 0
                      TX-1875 0
                      trans-4-hydroxycyclohexanecarboxylic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        hydroxy carboxylic acid 3656
                                          4-hydroxy carboxylic acid 2
                                            4-hydroxy monocarboxylic acid 2
                                              (4R)-4-hydroxypentanoic acid + 0
                                              2-dehydro-3-deoxy-D-arabinonic acid 0
                                              3-dehydroquinic acid 0
                                              3-dehydroshikimic acid 0
                                              4-hydroxy-2-oxohexanoic acid + 0
                                              4-hydroxy-2-oxopentanoic acid + 0
                                              4-hydroxybutyric acid + 2
                                              4-hydroxylauric acid + 0
                                              5-chloro-4-hydroxy-2-oxopentanoic acid 0
                                              TX-1875 0
                                              trans-4-hydroxycyclohexanecarboxylic acid 0
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