sorbic acid - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	sorbic acid	go back to main search page
Accession:	CHEBI:35962	browse the term
Definition:	A hexadienoic acid with double bonds at C-2 and C-4; it has four geometrical isomers, of which the trans,trans-form is naturally occurring.
Synonyms:	exact_synonym:	hexa-2,4-dienoic acid
	related_synonym:	(2-butenylidene) acetic acid; 2,4-Hexadiensaeure; 2,4-SA; 2,4-hexadienoic acid; 2-propenylacrylic acid; Formula=C6H8O2; InChI=1S/C6H8O2/c1-2-3-4-5-6(7)8/h2-5H,1H3,(H,7,8); InChIKey=WSWCOQWTEOXDQX-UHFFFAOYSA-N; SA; SMILES=[H]C(C)=CC([H])=CC(O)=O; Sorbinsaeure; crotylidene acetic acid
	xref:	Beilstein:1741831; CAS:22500-92-1; PMID:11206806
	cyclic_relationship:	is_conjugate_acid_of CHEBI:36550

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Rat (10) Mouse (10) Human (10) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (10)

(2E,4E)-hexa-2,4-dienoic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

FOS like 1, AP-1 transcription factor subunit

increases expression

Sorbic Acid results in increased expression of FOSL1 protein

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

interferon gamma

multiple interactions

[Food Preservatives results in increased abundance of Sorbic Acid] which results in increased expression of IFNG mRNA

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 10

multiple interactions

[Food Preservatives results in increased abundance of Sorbic Acid] which results in increased expression of IL10 mRNA

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 1 beta

multiple interactions

[Food Preservatives results in increased abundance of Sorbic Acid] which results in increased expression of IL1B mRNA

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

[Food Preservatives results in increased abundance of Sorbic Acid] which results in increased expression of IL6 mRNA

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

orosomucoid 1

increases expression

Sorbic Acid results in increased expression of ORM1 protein

NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154

G

phosphate regulating endopeptidase homolog, X-linked

increases expression

Sorbic Acid results in increased expression of PHEX protein

NCBI chr X:37,607,553...37,856,183
Ensembl chr X:37,610,760...37,854,469

G

RAD51 associated protein 1

increases expression

Sorbic Acid results in increased expression of RAD51AP1 protein

NCBI chr 4:159,759,454...159,772,524
Ensembl chr 4:159,759,459...159,772,524

G

tumor necrosis factor

multiple interactions

[Food Preservatives results in increased abundance of Sorbic Acid] which results in increased expression of TNF mRNA

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

vascular endothelial growth factor A

increases expression

Sorbic Acid results in increased expression of VEGFA protein

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19800
chemical entity	19800
atom	19799
nonmetal atom	19686
carbon atom	19609
organic molecular entity	19609
lipid	17493
fatty acid	16011
medium-chain fatty acid	3557
sorbic acid	10
(2E,4E)-hexa-2,4-dienoic acid +	10
(2E,4Z)-6-(4-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid	0
(2E,4Z)-hexa-2,4-dienoic acid	0
(2Z,4E)-hexa-2,4-dienoic acid	0
(2Z,4Z)-hexa-2,4-dienoic acid	0
2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate	0
2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid	0
2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid	0
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid	0
ethyl sorbate	0
Path 2
Term	Annotations
CHEBI ontology	19800
subatomic particle	19799
composite particle	19799
hadron	19799
baryon	19799
nucleon	19799
atomic nucleus	19799
atom	19799
main group element atom	19698
p-block element atom	19698
carbon group element atom	19619
carbon atom	19609
organic molecular entity	19609
organic group	18718
organic divalent group	18702
organodiyl group	18702
carbonyl group	18651
carbonyl compound	18651
carboxylic acid	18346
monocarboxylic acid	17622
fatty acid	16011
unsaturated fatty acid	957
polyunsaturated fatty acid	692
hexadienoic acid	10
sorbic acid	10
(2E,4E)-hexa-2,4-dienoic acid +	10
(2E,4Z)-6-(4-chlorophenyl)-2-hydroxy-6-oxohexa-2,4-dienoic acid	0
(2E,4Z)-hexa-2,4-dienoic acid	0
(2Z,4E)-hexa-2,4-dienoic acid	0
(2Z,4Z)-hexa-2,4-dienoic acid	0
2-Hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate	0
2-hydroxy-6-(2-hydroxyphenoxy)-6-oxo-cis,cis-hexa-2,4-dienoic acid	0
2-hydroxy-6-(2-hydroxyphenyl)-6-oxo-cis,cis-hexa-2,4-dienoic acid	0
2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid	0
ethyl sorbate	0

paths to the root