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ONTOLOGY REPORT - ANNOTATIONS


Term:2-oxo monocarboxylic acid
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Accession:CHEBI:35910 term browser browse the term
Definition:Any monocarboxylic acid having a 2-oxo substituent.
Synonyms:exact_synonym: 2-oxo carboxylic acids
 related_synonym: 2-Oxocarboxylate;   2-oxo acid;   2-oxo monocarboxylic acids;   Formula=C2HO3R;   SMILES=OC(=O)C([*])=O
 alt_id: CHEBI:11634;   CHEBI:1238;   CHEBI:13195;   CHEBI:13594;   CHEBI:19736;   CHEBI:35909
 xref: KEGG:C00161
 cyclic_relationship: is_conjugate_acid_of CHEBI:35179


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2-oxobutanoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:6480464
3-bromopyruvic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Gapdh glyceraldehyde-3-phosphate dehydrogenase JBrowse link 4 157,676,336 157,680,322 RGD:6480464
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:6480464
G Hk1 hexokinase 1 JBrowse link 20 31,911,460 31,979,780 RGD:6480464
G Hk2 hexokinase 2 JBrowse link 4 113,559,396 113,609,897 RGD:6480464
G Ldha lactate dehydrogenase A JBrowse link 1 102,900,288 102,909,713 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mcl1 MCL1 apoptosis regulator, BCL2 family member JBrowse link 2 197,786,212 197,788,992 RGD:6480464
G Mtor mechanistic target of rapamycin kinase JBrowse link 5 165,263,813 165,373,967 RGD:6480464
G Rps6kb1 ribosomal protein S6 kinase B1 JBrowse link 10 73,824,200 73,865,503 RGD:6480464
G Sdha succinate dehydrogenase complex flavoprotein subunit A JBrowse link 1 31,545,631 31,570,601 RGD:6480464
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:6480464
G Slc2a1 solute carrier family 2 member 1 JBrowse link 5 138,154,677 138,182,897 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Stk11 serine/threonine kinase 11 JBrowse link 7 12,440,751 12,457,513 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464
3-hydroxypyruvic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aldh2 aldehyde dehydrogenase 2 family member JBrowse link 12 40,466,418 40,498,813 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
3-methyl-2-oxobutanoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 4 175,969,549 176,026,227 RGD:6480464
3-methyl-2-oxovaleric acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
4-methyl-2-oxopentanoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dek DEK proto-oncogene JBrowse link 17 17,965,872 17,987,836 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Slco1a4 solute carrier organic anion transporter family, member 1a4 JBrowse link 4 175,969,549 176,026,227 RGD:6480464
4-methylthio-2-oxobutanoic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ctbp2 C-terminal binding protein 2 JBrowse link 1 205,001,354 205,030,565 RGD:6480464
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:6480464
G Kyat1 kynurenine aminotransferase 1 JBrowse link 3 8,752,289 8,785,617 RGD:6480464
G Odc1 ornithine decarboxylase 1 JBrowse link 6 42,852,529 42,859,142 RGD:6480464
glyoxylic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G G6pd glucose-6-phosphate dehydrogenase JBrowse link X 156,274,800 156,293,935 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Spp1 secreted phosphoprotein 1 JBrowse link 14 6,673,686 6,679,965 RGD:6480464
keto-phenylpyruvic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Col2a1 collagen type II alpha 1 chain JBrowse link 7 139,454,945 139,484,403 RGD:6480464
G Slc22a7 solute carrier family 22 member 7 JBrowse link 9 16,925,321 16,931,119 RGD:6480464
methyl pyruvate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
phenylglyoxylic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
G Ephx1 epoxide hydrolase 1 JBrowse link 13 99,271,390 99,300,580 RGD:6480464
pyruvate ester term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nqo1 NAD(P)H quinone dehydrogenase 1 JBrowse link 19 38,422,210 38,437,103 RGD:25823189
pyruvic acid term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acaca acetyl-CoA carboxylase alpha JBrowse link 10 71,519,392 71,719,910 RGD:6480464
G Adrb3 adrenoceptor beta 3 JBrowse link 16 69,003,541 69,006,632 RGD:6480464
G Atp5f1a ATP synthase F1 subunit alpha JBrowse link 18 74,156,553 74,164,490 RGD:6480464
G Becn1 beclin 1 JBrowse link 10 89,209,944 89,225,297 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp9 caspase 9 JBrowse link 5 160,356,211 160,373,774 RGD:6480464
G Ctbp1 C-terminal binding protein 1 JBrowse link 14 82,762,109 82,789,350 RGD:6480464
G Ctbp2 C-terminal binding protein 2 JBrowse link 1 205,001,354 205,030,565 RGD:6480464
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 JBrowse link 1 266,422,127 266,429,947 RGD:6480464
G Dek DEK proto-oncogene JBrowse link 17 17,965,872 17,987,836 RGD:6480464
G Faslg Fas ligand JBrowse link 13 79,696,811 79,717,581 RGD:6480464
G Gcg glucagon JBrowse link 3 48,442,635 48,451,650 RGD:6480464
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 JBrowse link 1 141,874,354 141,893,674 RGD:6480464
G Il22 interleukin 22 JBrowse link 7 61,236,037 61,240,502 RGD:6480464
G Il4 interleukin 4 JBrowse link 10 38,963,979 38,969,531 RGD:6480464
G Ins2 insulin 2 JBrowse link 1 215,856,967 215,858,034 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Mt-co1 mitochondrially encoded cytochrome c oxidase I JBrowse link MT 5,323 6,867 RGD:6480464
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 JBrowse link 1 264,298,671 264,303,712 RGD:6480464
G Nr5a1 nuclear receptor subfamily 5, group A, member 1 JBrowse link 3 22,998,900 23,020,441 RGD:6480464
G Pdk4 pyruvate dehydrogenase kinase 4 JBrowse link 4 30,546,772 30,556,774 RGD:6480464
G Ppargc1a PPARG coactivator 1 alpha JBrowse link 14 63,095,291 63,190,688 RGD:6480464
G Sirt1 sirtuin 1 JBrowse link 20 26,831,971 26,851,587 RGD:6480464
G Slc16a1 solute carrier family 16 member 1 JBrowse link 2 207,108,552 207,129,352 RGD:6480464
G Slc2a4 solute carrier family 2 member 4 JBrowse link 10 56,552,921 56,558,562 RGD:6480464
G Sod1 superoxide dismutase 1 JBrowse link 11 30,363,282 30,368,858 RGD:6480464
G Tfam transcription factor A, mitochondrial JBrowse link 20 18,594,057 18,606,106 RGD:6480464
G Tp53 tumor protein p53 JBrowse link 10 56,186,299 56,198,449 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      chemical role 19251
        donor 18349
          Bronsted acid 18206
            oxoacid 18157
              carbon oxoacid 18030
                carboxylic acid 18019
                  monocarboxylic acid 17277
                    oxo monocarboxylic acid 6263
                      2-oxo monocarboxylic acid 57
                        (3E)-3-[(1R,5R,6S)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]pyruvic acid 0
                        (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoic acid 0
                        (3E)-4-(5-amino-2-hydroxyphenyl)-2-oxobut-3-enoic acid 0
                        (3S)-3-methyl-2-oxo-3-phenylpropanoic acid 0
                        (4-bromophenylsulfanyl)pyruvic acid 0
                        (R)-3,4-dihydroxy-2-oxobutanoic acid 0
                        (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid 0
                        (S)-3,4-dihydroxy-2-oxobutanoic acid 0
                        (S)-3-hydroxy-2-oxo-3-phenylpropanoic acid 0
                        2-aminophenylglyoxylic acid 0
                        2-dehydro-3-deoxy-D-arabinonic acid 0
                        2-dehydro-3-deoxy-L-arabinonic acid 0
                        2-hydroxy-3-methylbenzylidenepyruvic acid 0
                        2-hydroxy-4-hydroxymethylbenzylidenepyruvic acid 0
                        2-oxo-3-(5-oxofuran-2-ylidene)propanoic acid 0
                        2-oxobut-3-enoic acid 0
                        2-oxobutanoic acid + 1
                        2-oxododecanoic acid 0
                        2-oxoglutaramic acid + 0
                        2-oxohex-4-enoic acid + 0
                        2-oxohexanoic acid 0
                        2-oxononanoic acid 0
                        2-oxooctadecanoic acid 0
                        2-oxopent-4-enoic acid 0
                        2-oxopenta-3,4-dienoic acid 0
                        2-oxopentanoic acid 0
                        2-oxophytanic acid 0
                        3,4-dihydro-4-hydroxyphenylpyruvic acid + 0
                        3,4-dihydroxyphenylpyruvic acid 0
                        3,5-dibromo-4-hydroxyphenylpyruvic acid 0
                        3,5-dihydroxyphenylglyoxylic acid 0
                        3,5-dinitro-4-hydroxyphenylpyruvic acid 0
                        3-(3-methoxy-4-phenylmethoxyphenyl)-2-oxopropanoic acid 0
                        3-(4-aminophenyl)pyruvic acid 0
                        3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvic acid + 0
                        3-(imidazol-4-yl)pyruvic acid 0
                        3-(indol-3-yl)-2-oxobutyric acid + 0
                        3-(indol-3-yl)pyruvic acid 0
                        3-[(1R,2S,5R,6S)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]pyruvic acid 0
                        3-bromopyruvic acid 17
                        3-dimethylallyl-4-hydroxyphenylpyruvic acid 0
                        3-fluoropyruvic acid 0
                        3-hydroxy-3-methyl-2-oxobutanoic acid 0
                        3-hydroxy-3-methyl-2-oxopentanoic acid + 0
                        3-hydroxypyruvic acid 2
                        3-mercaptopyruvic acid 0
                        3-methyl-2-oxobutanoic acid 2
                        3-methyl-2-oxovaleric acid + 1
                        3-phosphonopyruvic acid 0
                        3-sulfinylpyruvic acid 0
                        4-(2-aminophenyl)-2,4-dioxobutanoic acid 0
                        4-(3-hydroxy-1-benzothiophen-2-yl)-2-oxobut-3-enoic acid + 0
                        4-(hydroxymethylphosphinyl)-2-oxobutyric acid 0
                        4-amino-4-deoxyprephenic acid 0
                        4-hydroxy-2-oxohexanoic acid + 0
                        4-hydroxy-2-oxopentanoic acid + 0
                        4-methyl-2-oxopentanoic acid 3
                        5-amino-2-oxopentanoic acid 0
                        5-chloro-4-hydroxy-2-oxopentanoic acid 0
                        5-guanidino-2-oxopentanoic acid 0
                        5-guanidino-3-methyl-2-oxopentanoic acid 0
                        6-acetamido-2-oxohexanoic acid 0
                        6-amino-2-oxohexanoic acid + 0
                        6-hydroxy-2-oxohexanoic acid 0
                        Loniphenyruviridoside B, (rel)- 0
                        Loniphenyruviridoside C 0
                        N-methyl-2-oxoglutaramic acid 0
                        Vanillactic acid 0
                        Vanilpyruvic acid 0
                        beta-(methylenecyclopropyl)pyruvic acid 0
                        cis-4-(1-hydroxy-2-naphthyl)-2-oxobut-3-enoic acid 0
                        glyoxylic acid + 5
                        keto-phenylpyruvic acid + 2
                        lignin cw compound-2040 0
                        lignin cw compound-2041 0
                        lignin cw compound-2042 0
                        lignin cw compound-3052 0
                        lignin cw compound-3056 0
                        omega-(methylthio)-2-oxocarboxylic acid + 4
                        oxaluric acid 0
                        phenylglyoxylic acid + 2
                        pyruvic acid + 48
                        tetrahydro-4-hydroxyphenylpyruvic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    p-block element atom 19655
                      carbon group element atom 19548
                        carbon atom 19537
                          organic molecular entity 19537
                            organic group 18451
                              organic divalent group 18445
                                organodiyl group 18445
                                  carbonyl group 18346
                                    carbonyl compound 18346
                                      carboxylic acid 18019
                                        monocarboxylic acid 17277
                                          oxo monocarboxylic acid 6263
                                            2-oxo monocarboxylic acid 57
                                              (3E)-3-[(1R,5R,6S)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-ylidene]pyruvic acid 0
                                              (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoic acid 0
                                              (3E)-4-(5-amino-2-hydroxyphenyl)-2-oxobut-3-enoic acid 0
                                              (3S)-3-methyl-2-oxo-3-phenylpropanoic acid 0
                                              (4-bromophenylsulfanyl)pyruvic acid 0
                                              (R)-3,4-dihydroxy-2-oxobutanoic acid 0
                                              (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoic acid 0
                                              (S)-3,4-dihydroxy-2-oxobutanoic acid 0
                                              (S)-3-hydroxy-2-oxo-3-phenylpropanoic acid 0
                                              2-aminophenylglyoxylic acid 0
                                              2-dehydro-3-deoxy-D-arabinonic acid 0
                                              2-dehydro-3-deoxy-L-arabinonic acid 0
                                              2-hydroxy-3-methylbenzylidenepyruvic acid 0
                                              2-hydroxy-4-hydroxymethylbenzylidenepyruvic acid 0
                                              2-oxo-3-(5-oxofuran-2-ylidene)propanoic acid 0
                                              2-oxobut-3-enoic acid 0
                                              2-oxobutanoic acid + 1
                                              2-oxododecanoic acid 0
                                              2-oxoglutaramic acid + 0
                                              2-oxohex-4-enoic acid + 0
                                              2-oxohexanoic acid 0
                                              2-oxononanoic acid 0
                                              2-oxooctadecanoic acid 0
                                              2-oxopent-4-enoic acid 0
                                              2-oxopenta-3,4-dienoic acid 0
                                              2-oxopentanoic acid 0
                                              2-oxophytanic acid 0
                                              3,4-dihydro-4-hydroxyphenylpyruvic acid + 0
                                              3,4-dihydroxyphenylpyruvic acid 0
                                              3,5-dibromo-4-hydroxyphenylpyruvic acid 0
                                              3,5-dihydroxyphenylglyoxylic acid 0
                                              3,5-dinitro-4-hydroxyphenylpyruvic acid 0
                                              3-(3-methoxy-4-phenylmethoxyphenyl)-2-oxopropanoic acid 0
                                              3-(4-aminophenyl)pyruvic acid 0
                                              3-(4-hydroxycyclohex-2-en-1-ylidene)pyruvic acid + 0
                                              3-(imidazol-4-yl)pyruvic acid 0
                                              3-(indol-3-yl)-2-oxobutyric acid + 0
                                              3-(indol-3-yl)pyruvic acid 0
                                              3-[(1R,2S,5R,6S)-5-hydroxy-7-oxabicyclo[4.1.0]heptan-2-yl]pyruvic acid 0
                                              3-bromopyruvic acid 17
                                              3-dimethylallyl-4-hydroxyphenylpyruvic acid 0
                                              3-fluoropyruvic acid 0
                                              3-hydroxy-3-methyl-2-oxobutanoic acid 0
                                              3-hydroxy-3-methyl-2-oxopentanoic acid + 0
                                              3-hydroxypyruvic acid 2
                                              3-mercaptopyruvic acid 0
                                              3-methyl-2-oxobutanoic acid 2
                                              3-methyl-2-oxovaleric acid + 1
                                              3-phosphonopyruvic acid 0
                                              3-sulfinylpyruvic acid 0
                                              4-(2-aminophenyl)-2,4-dioxobutanoic acid 0
                                              4-(3-hydroxy-1-benzothiophen-2-yl)-2-oxobut-3-enoic acid + 0
                                              4-(hydroxymethylphosphinyl)-2-oxobutyric acid 0
                                              4-amino-4-deoxyprephenic acid 0
                                              4-hydroxy-2-oxohexanoic acid + 0
                                              4-hydroxy-2-oxopentanoic acid + 0
                                              4-methyl-2-oxopentanoic acid 3
                                              5-amino-2-oxopentanoic acid 0
                                              5-chloro-4-hydroxy-2-oxopentanoic acid 0
                                              5-guanidino-2-oxopentanoic acid 0
                                              5-guanidino-3-methyl-2-oxopentanoic acid 0
                                              6-acetamido-2-oxohexanoic acid 0
                                              6-amino-2-oxohexanoic acid + 0
                                              6-hydroxy-2-oxohexanoic acid 0
                                              Loniphenyruviridoside B, (rel)- 0
                                              Loniphenyruviridoside C 0
                                              N-methyl-2-oxoglutaramic acid 0
                                              Vanillactic acid 0
                                              Vanilpyruvic acid 0
                                              beta-(methylenecyclopropyl)pyruvic acid 0
                                              cis-4-(1-hydroxy-2-naphthyl)-2-oxobut-3-enoic acid 0
                                              glyoxylic acid + 5
                                              keto-phenylpyruvic acid + 2
                                              lignin cw compound-2040 0
                                              lignin cw compound-2041 0
                                              lignin cw compound-2042 0
                                              lignin cw compound-3052 0
                                              lignin cw compound-3056 0
                                              omega-(methylthio)-2-oxocarboxylic acid + 4
                                              oxaluric acid 0
                                              phenylglyoxylic acid + 2
                                              pyruvic acid + 48
                                              tetrahydro-4-hydroxyphenylpyruvic acid + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.