CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: phosphanes
Accession: CHEBI:35878
browse the term
Definition: The saturated hydrides of tervalent phosphorus having the general formula PnHn+2.
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ABCB10
ATP binding cassette subfamily B member 10
increases expression
ISO
phosphine results in increased expression of ABCB10 mRNA
CTD
PMID:34427094
NCBI chr 1:229,516,582...229,558,707
Ensembl chr 1:229,516,582...229,558,707
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AGTR1
angiotensin II receptor type 1
increases expression
ISO
phosphine results in increased expression of AGTR1 mRNA
CTD
PMID:34427094
NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
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APLNR
apelin receptor
decreases expression
ISO
phosphine results in decreased expression of APLNR mRNA
CTD
PMID:34427094
NCBI chr11:57,233,591...57,237,250
Ensembl chr11:57,233,577...57,237,250
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BMP6
bone morphogenetic protein 6
affects expression
ISO
phosphine affects the expression of BMP6 mRNA
CTD
PMID:34427094
NCBI chr 6:7,726,099...7,881,728
Ensembl chr 6:7,726,099...7,881,728
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BMPR1A
bone morphogenetic protein receptor type 1A
increases expression
ISO
phosphine results in increased expression of BMPR1A mRNA
CTD
PMID:34427094
NCBI chr10:86,755,763...86,932,844
Ensembl chr10:86,756,596...86,932,825
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CBL
Cbl proto-oncogene
affects expression
ISO
phosphine affects the expression of CBL mRNA
CTD
PMID:34427094
NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
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CCN2
cellular communication network factor 2
increases expression
ISO
phosphine results in increased expression of CTGF mRNA
CTD
PMID:34427094
NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372
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CIAO2B
cytosolic iron-sulfur assembly component 2B
increases expression
ISO
phosphine results in increased expression of CIAO2B mRNA
CTD
PMID:34427094
NCBI chr16:66,932,065...66,934,402
Ensembl chr16:66,932,065...66,934,423
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CP
ceruloplasmin
increases expression
ISO
phosphine results in increased expression of CP mRNA
CTD
PMID:34427094
NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829
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EPAS1
endothelial PAS domain protein 1
increases expression
ISO
phosphine results in increased expression of EPAS1 mRNA
CTD
PMID:34427094
NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
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EPOR
erythropoietin receptor
affects expression
ISO
phosphine affects the expression of EPOR mRNA
CTD
PMID:34427094
NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342
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GRB2
growth factor receptor bound protein 2
decreases expression
ISO
phosphine results in decreased expression of GRB2 mRNA
CTD
PMID:34427094
NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709
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HMOX1
heme oxygenase 1
increases expression
ISO
phosphine results in increased expression of HMOX1 mRNA
CTD
PMID:34427094
NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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HSCB
HscB mitochondrial iron-sulfur cluster cochaperone
increases expression
ISO
phosphine results in increased expression of HSCB mRNA
CTD
PMID:34427094
NCBI chr22:28,742,032...28,757,510
Ensembl chr22:28,742,039...28,757,515
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IREB2
iron responsive element binding protein 2
affects expression
ISO
phosphine affects the expression of IREB2 mRNA
CTD
PMID:34427094
NCBI chr15:78,437,431...78,501,453
Ensembl chr15:78,437,431...78,501,453
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JAK2
Janus kinase 2
decreases expression
ISO
phosphine results in decreased expression of JAK2 mRNA
CTD
PMID:34427094
NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
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JUN
Jun proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
phosphine results in increased expression of JUN mRNA
CTD
PMID:34427094
NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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LYRM4
LYR motif containing 4
increases expression
ISO
phosphine results in increased expression of LYRM4 mRNA
CTD
PMID:34427094
NCBI chr 6:5,031,753...5,260,950
Ensembl chr 6:5,103,629...5,260,950
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NOS3
nitric oxide synthase 3
increases expression
ISO
phosphine results in increased expression of NOS3 mRNA
CTD
PMID:34427094
NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588
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PCBP1
poly(rC) binding protein 1
affects expression
ISO
phosphine affects the expression of PCBP1 mRNA
CTD
PMID:34427094
NCBI chr 2:70,087,477...70,089,203
Ensembl chr 2:70,087,477...70,089,203
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PDK1
pyruvate dehydrogenase kinase 1
affects expression
ISO
phosphine affects the expression of PDK1 mRNA
CTD
PMID:34427094
NCBI chr 2:172,555,373...172,724,312
Ensembl chr 2:172,555,373...172,608,669
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SERPINE1
serpin family E member 1
increases expression
ISO
phosphine results in increased expression of SERPINE1 mRNA
CTD
PMID:34427094
NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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SLC25A37
solute carrier family 25 member 37
increases expression
ISO
phosphine results in increased expression of SLC25A37 mRNA
CTD
PMID:34427094
NCBI chr 8:23,528,956...23,575,463
Ensembl chr 8:23,528,956...23,575,463
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SMAD4
SMAD family member 4
increases expression
ISO
phosphine results in increased expression of SMAD4 mRNA
CTD
PMID:34427094
NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045
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SOCS1
suppressor of cytokine signaling 1
increases expression
ISO
phosphine results in increased expression of SOCS1 mRNA
CTD
PMID:34427094
NCBI chr16:11,254,417...11,256,204
Ensembl chr16:11,254,417...11,256,204
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SOCS3
suppressor of cytokine signaling 3
increases expression
ISO
phosphine results in increased expression of SOCS3 mRNA
CTD
PMID:34427094
NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
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SRC
SRC proto-oncogene, non-receptor tyrosine kinase
increases expression
ISO
phosphine results in increased expression of SRC mRNA
CTD
PMID:34427094
NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050
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STAT5A
signal transducer and activator of transcription 5A
decreases expression
ISO
phosphine results in decreased expression of STAT5 mRNA
CTD
PMID:34427094
NCBI chr17:42,287,439...42,311,943
Ensembl chr17:42,287,547...42,311,943
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TFRC
transferrin receptor
increases expression
ISO
phosphine results in increased expression of TFRC mRNA
CTD
PMID:34427094
NCBI chr 3:196,049,284...196,082,090
Ensembl chr 3:196,012,511...196,082,153
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TWSG1
twisted gastrulation BMP signaling modulator 1
decreases expression
ISO
phosphine results in decreased expression of TWSG1 mRNA
CTD
PMID:34427094
NCBI chr18:9,334,773...9,402,420
Ensembl chr18:9,334,767...9,402,420
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AS3MT
arsenite methyltransferase
multiple interactions affects folding increases reduction
ISO EXP
tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of Arsenic] tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to and results in increased methylation of arsenite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein binds to S-Adenosylmethionine]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of dimethylarsinous acid]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased chemical synthesis of methylarsonite]; tris(2-carboxyethyl)phosphine promotes the reaction [AS3MT protein results in increased methylation of arsenite] tris(2-carboxyethyl)phosphine affects the folding of AS3MT protein tris(2-carboxyethyl)phosphine results in increased reduction of AS3MT protein
CTD
PMID:15025511 PMID:22955273 PMID:25349987
NCBI chr10:102,869,470...102,901,899
Ensembl chr10:102,869,470...102,901,899
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CRYGD
crystallin gamma D
decreases oxidation
EXP
[tris(2-carboxyethyl)phosphine results in decreased oxidation of CRYGD protein] which results in decreased oxidation of CRYGD mRNA mutant form; tris(2-carboxyethyl)phosphine results in decreased oxidation of CRYGD protein
CTD
PMID:30242128
NCBI chr 2:208,121,607...208,124,524
Ensembl chr 2:208,121,607...208,124,524
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MTF1
metal regulatory transcription factor 1
multiple interactions
EXP
tris(2-carboxyethyl)phosphine inhibits the reaction [Cadmium promotes the reaction [MTF1 protein binds to MTF1 protein]]; tris(2-carboxyethyl)phosphine inhibits the reaction [Copper promotes the reaction [MTF1 protein binds to MTF1 protein]]
CTD
PMID:22057392
NCBI chr 1:37,809,574...37,859,592
Ensembl chr 1:37,809,574...37,859,592
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NEIL1
nei like DNA glycosylase 1
multiple interactions
EXP
[tris(2-carboxyethyl)phosphine co-treated with Edetic Acid] inhibits the reaction [Copper results in decreased activity of NEIL1 protein]; tris(2-carboxyethyl)phosphine inhibits the reaction [Hydrogen Peroxide results in decreased activity of NEIL1 protein]
CTD
PMID:20622253
NCBI chr15:75,347,039...75,357,115
Ensembl chr15:75,346,955...75,357,115
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SLC34A1
solute carrier family 34 member 1
decreases activity
ISO
tris(2-carboxyethyl)phosphine results in decreased activity of SLC34A1 protein
CTD
PMID:10926679
NCBI chr 5:177,384,434...177,398,848
Ensembl chr 5:177,379,235...177,398,848
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TXN
thioredoxin
multiple interactions
EXP
tris(2-carboxyethyl)phosphine inhibits the reaction [chromium hexavalent ion results in increased oxidation of TXN protein]; tris(2-carboxyethyl)phosphine inhibits the reaction [sodium chromate(VI) results in increased oxidation of TXN protein]
CTD
PMID:19135121 PMID:19703554
NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
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TXN2
thioredoxin 2
multiple interactions
EXP
tris(2-carboxyethyl)phosphine inhibits the reaction [chromium hexavalent ion results in increased oxidation of TXN2 protein]
CTD
PMID:19703554
NCBI chr22:36,467,046...36,481,640
Ensembl chr22:36,467,046...36,481,640
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