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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1-methylphenanthrene
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Accession:CHEBI:35860 term browser browse the term
Definition:A member of the class of phenanthrenes that is phenanthrene substituted by a methyl group at position 1.
Synonyms:related_synonym: Formula=C15H12;   InChI=1S/C15H12/c1-11-5-4-8-15-13(11)10-9-12-6-2-3-7-14(12)15/h2-10H,1H3;   InChIKey=DOWJXOHBNXRUOD-UHFFFAOYSA-N;   SMILES=Cc1cccc2c1ccc1ccccc21
 xref: Beilstein:1861851;   CAS:832-69-9;   KEGG:C19457
 xref_mesh: MESH:C041507
 xref: PMID:23553963;   PMID:24407477;   PMID:24709094;   PMID:6338362;   Reaxys:1861851


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1-methylphenanthrene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of A2M mRNA CTD PMID:17690111 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions
EXP 1-methylphenanthrene results in increased activity of AHR protein
[1-methylphenanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA
CTD PMID:11339718 PMID:17941746 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aldob aldolase, fructose-bisphosphate B multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of ALDOB mRNA CTD PMID:17690111 NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
JBrowse link
G Amacr alpha-methylacyl-CoA racemase multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of AMACR mRNA CTD PMID:17690111 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
JBrowse link
G Apoc3 apolipoprotein C3 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of APOC3 mRNA CTD PMID:17690111 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Ar androgen receptor multiple interactions EXP 1-methylphenanthrene inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CDKN1A mRNA CTD PMID:17690111 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CEACAM6 mRNA CTD PMID:17690111 NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
affects expression
multiple interactions
EXP
ISO
1-methylphenanthrene results in increased expression of CYP1A1 protein
1-methylphenanthrene affects the expression of CYP1A1 mRNA
1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1A1 mRNA]; [1-methylphenanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CYP1A1 mRNA
CTD PMID:11339718 PMID:17690111 PMID:17941746 PMID:27099206 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 affects expression
multiple interactions
EXP 1-methylphenanthrene affects the expression of CYP1B1 mRNA
1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]
CTD PMID:27099206 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Ece1 endothelin converting enzyme 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of ECE1 mRNA CTD PMID:17690111 NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of G6PD mRNA CTD PMID:17690111 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of GADD45A mRNA CTD PMID:17690111 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Gck glucokinase multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of GCK mRNA CTD PMID:17690111 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of HIF1A mRNA CTD PMID:17690111 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of IGF1 mRNA CTD PMID:17690111 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of IGFBP1 mRNA CTD PMID:17690111 NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
JBrowse link
G Klf6 Kruppel-like factor 6 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of KLF6 mRNA CTD PMID:17690111 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G LOC299277 similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SERPINA3 mRNA CTD PMID:17690111 NCBI chr 6:127,871,895...127,888,287
Ensembl chr 6:127,872,666...127,886,540
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of MCL1 mRNA CTD PMID:17690111 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SAT1 mRNA CTD PMID:17690111 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SPP1 mRNA CTD PMID:17690111 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Tp53 tumor protein p53 increases phosphorylation EXP 1-methylphenanthrene results in increased phosphorylation of TP53 protein CTD PMID:17941746 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 multiple interactions ISO [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of XRCC1 mRNA CTD PMID:17690111 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19841
    role 19792
      biological role 19792
        xenobiotic 18434
          phenanthrenes 110
            1-methylphenanthrene 24
Path 2
Term Annotations click to browse term
  CHEBI ontology 19841
    subatomic particle 19839
      composite particle 19839
        hadron 19839
          baryon 19839
            nucleon 19839
              atomic nucleus 19839
                atom 19839
                  main group element atom 19732
                    p-block element atom 19732
                      carbon group element atom 19636
                        carbon atom 19625
                          organic molecular entity 19625
                            organic molecule 19556
                              organic cyclic compound 19365
                                carbocyclic compound 18273
                                  carbopolycyclic compound 16980
                                    carbotricyclic compound 1053
                                      phenanthrenes 110
                                        1-methylphenanthrene 24
paths to the root