CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: 1-methylphenanthrene
Accession: CHEBI:35860
browse the term
Definition: A member of the class of phenanthrenes that is phenanthrene substituted by a methyl group at position 1.
Synonyms: related_synonym: Formula=C15H12; InChI=1S/C15H12/c1-11-5-4-8-15-13(11)10-9-12-6-2-3-7-14(12)15/h2-10H,1H3; InChIKey=DOWJXOHBNXRUOD-UHFFFAOYSA-N; SMILES=Cc1cccc2c1ccc1ccccc21
xref: Beilstein:1861851; CAS:832-69-9; KEGG:C19457
xref_mesh: MESH:C041507
xref: PMID:23553963; PMID:24407477; PMID:24709094; PMID:6338362; Reaxys:1861851
G
A2m
alpha-2-macroglobulin
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of A2M mRNA
CTD
PMID:17690111
NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
G
Ahr
aryl hydrocarbon receptor
increases activity multiple interactions
EXP
1-methylphenanthrene results in increased activity of AHR protein [1-methylphenanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA
CTD
PMID:11339718 PMID:17941746
NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
G
Aldob
aldolase, fructose-bisphosphate B
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of ALDOB mRNA
CTD
PMID:17690111
NCBI chr 5:64,805,772...64,818,813
Ensembl chr 5:64,805,773...64,818,824
G
Amacr
alpha-methylacyl-CoA racemase
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of AMACR mRNA
CTD
PMID:17690111
NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
G
Apoc3
apolipoprotein C3
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of APOC3 mRNA
CTD
PMID:17690111
NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
G
Ar
androgen receptor
multiple interactions
EXP
1-methylphenanthrene inhibits the reaction [Metribolone binds to AR protein]
CTD
PMID:3695475
NCBI chr X:67,656,253...67,828,998
Ensembl chr X:67,656,253...67,829,026
G
Cdkn1a
cyclin-dependent kinase inhibitor 1A
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CDKN1A mRNA
CTD
PMID:17690111
NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
G
Ceacam6
CEA cell adhesion molecule 6
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CEACAM6 mRNA
CTD
PMID:17690111
NCBI chr 1:81,683,500...81,701,230
Ensembl chr 1:81,683,463...81,701,317
G
Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression affects expression multiple interactions
EXP ISO
1-methylphenanthrene results in increased expression of CYP1A1 protein 1-methylphenanthrene affects the expression of CYP1A1 mRNA 1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1A1 mRNA]; [1-methylphenanthrene results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA [Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of CYP1A1 mRNA
CTD
PMID:11339718 PMID:17690111 PMID:17941746 PMID:27099206
NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
G
Cyp1b1
cytochrome P450, family 1, subfamily b, polypeptide 1
affects expression multiple interactions
EXP
1-methylphenanthrene affects the expression of CYP1B1 mRNA 1-methylphenanthrene affects the reaction [Benzo(a)pyrene affects the expression of CYP1B1 mRNA]
CTD
PMID:27099206
NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
G
Ece1
endothelin converting enzyme 1
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of ECE1 mRNA
CTD
PMID:17690111
NCBI chr 5:156,215,469...156,318,652
Ensembl chr 5:156,215,417...156,318,671
G
G6pd
glucose-6-phosphate dehydrogenase
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of G6PD mRNA
CTD
PMID:17690111
NCBI chr X:156,274,800...156,293,935
Ensembl chr X:156,274,800...156,293,926
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of GADD45A mRNA
CTD
PMID:17690111
NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
G
Gck
glucokinase
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of GCK mRNA
CTD
PMID:17690111
NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
G
Hif1a
hypoxia inducible factor 1 subunit alpha
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of HIF1A mRNA
CTD
PMID:17690111
NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
G
Igf1
insulin-like growth factor 1
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of IGF1 mRNA
CTD
PMID:17690111
NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
G
Igfbp1
insulin-like growth factor binding protein 1
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of IGFBP1 mRNA
CTD
PMID:17690111
NCBI chr14:87,448,716...87,453,783
Ensembl chr14:87,448,692...87,453,785
G
Klf6
Kruppel-like factor 6
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of KLF6 mRNA
CTD
PMID:17690111
NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
G
LOC299277
similar to serine (or cysteine) peptidase inhibitor, clade A, member 3B
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SERPINA3 mRNA
CTD
PMID:17690111
NCBI chr 6:127,871,895...127,888,287
Ensembl chr 6:127,872,666...127,886,540
G
Mcl1
MCL1 apoptosis regulator, BCL2 family member
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of MCL1 mRNA
CTD
PMID:17690111
NCBI chr 2:197,786,212...197,788,992
G
Sat1
spermidine/spermine N1-acetyl transferase 1
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SAT1 mRNA
CTD
PMID:17690111
NCBI chr X:43,626,480...43,629,767
Ensembl chr X:43,625,169...43,629,765
G
Spp1
secreted phosphoprotein 1
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of SPP1 mRNA
CTD
PMID:17690111
NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
G
Tp53
tumor protein p53
increases phosphorylation
EXP
1-methylphenanthrene results in increased phosphorylation of TP53 protein
CTD
PMID:17941746
NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
G
Xrcc1
X-ray repair cross complementing 1
multiple interactions
ISO
[Benzo(a)pyrene co-treated with 1-methylphenanthrene] affects the expression of XRCC1 mRNA
CTD
PMID:17690111
NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
Term paths to the root one shortest all shortest one longest all longest one shortest and longest all