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ONTOLOGY REPORT - ANNOTATIONS


Term:lipoxygenase inhibitor
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Accession:CHEBI:35856 term browser browse the term
Definition:A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes.
Synonyms:related_synonym: lipooxygenase inhibitor;   lipoxygenase inhibitors


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  CHEBI ontology 19679
    role 19623
      biological role 19621
        biochemical role 19147
          enzyme inhibitor 17984
            EC 1.* (oxidoreductase) inhibitor 16370
              EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor 4447
                EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor 4447
                  lipoxygenase inhibitor 4142
                    (+)-lyoniresinol 4,4'-bis-O-beta-D-glucopyranoside 0
                    (10E,12Z,15Z)-9-hydroxy-10,12,15-octadecatrienoic acid methyl ester 0
                    (6Z,9Z,12Z,15Z)-henicosa-1,6,9,12,15-pentaene 0
                    1-[(3-methylbutanoyl)phloroglucinyl]-beta-D-glucopyranoside 0
                    1-[(pentanoyl)-phloroglucinyl]-beta-D-glucopyranoside 0
                    4-nitrocatechol + 2
                    EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor + 104
                    EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor + 3757
                    EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor + 627
                    ampelopsin B 0
                    asperenone 0
                    bacteriohopane-32,33,34,35-tetrol + 0
                    ballodiolic acid 0
                    ballotenic acid 0
                    clonixin 0
                    clonixin lysine salt 0
                    curcumin + 853
                    masoprocol 71
                    negundin B 0
                    nigerloxin 0
                    onosmin A + 0
                    onosmin B 0
                    patuletin 0
                    procyanidin C1 0
                    proglumetacin + 0
                    proglumetacin dimaleate 0
                    silychristin 2
                    tepoxalin 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.