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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lipoxygenase inhibitor
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Accession:CHEBI:35856 term browser browse the term
Definition:A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes.
Synonyms:related_synonym: lipooxygenase inhibitor;   lipoxygenase inhibitors

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      CHEBI ontology 19904
        role 19880
          biological role 19878
            biochemical role 19576
              enzyme inhibitor 18759
                EC 1.* (oxidoreductase) inhibitor 17560
                  EC 1.13.* [oxidoreductase acting on single donors with incorporation of molecular oxygen (oxygenases)] inhibitor 6155
                    EC 1.13.11.* (oxidoreductase acting on single donors and incorporating 2 O atoms) inhibitor 6155
                      lipoxygenase inhibitor 5890
                        (+)-lyoniresinol 4,4'-bis-O-beta-D-glucopyranoside 0
                        (10E,12Z,15Z)-9-hydroxy-10,12,15-octadecatrienoic acid methyl ester 0
                        (6Z,9Z,12Z,15Z)-henicosa-1,6,9,12,15-pentaene 0
                        1-[(3-methylbutanoyl)phloroglucinyl]-beta-D-glucopyranoside 0
                        1-[(pentanoyl)-phloroglucinyl]-beta-D-glucopyranoside 0
                        4-nitrocatechol + 3
                        EC (arachidonate 12-lipoxygenase) inhibitor + 143
                        EC (arachidonate 15-lipoxygenase) inhibitor + 5571
                        EC (arachidonate 5-lipoxygenase) inhibitor + 688
                        ampelopsin B 0
                        asperenone 0
                        bacteriohopane-32,33,34,35-tetrol + 0
                        ballodiolic acid 0
                        ballotenic acid 0
                        clonixin 0
                        clonixin lysine salt 0
                        curcumin + 935
                        masoprocol 71
                        negundin B 0
                        nigerloxin 0
                        onosmin A + 0
                        onosmin B 0
                        patuletin 0
                        procyanidin C1 0
                        proglumetacin + 0
                        proglumetacin dimaleate 0
                        silychristin 9
                        tepoxalin 5
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