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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:renal agent
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Accession:CHEBI:35846 term browser browse the term
Definition:A drug used for its effect on the kidneys' regulation of body fluid composition and volume.
Synonyms:related_synonym: renal agents


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apazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Apazone results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
benzbromarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Benzbromarone results in decreased activity of ABCB11 protein
Benzbromarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:20829430 PMID:23956101 PMID:24014644 PMID:28437613 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects expression EXP Benzbromarone affects the expression of ABCB1A mRNA CTD PMID:19483382 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Benzbromarone results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:22,133,984...22,192,687
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
affects activity
ISO Benzbromarone inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]; Benzbromarone inhibits the reaction [ABCC1 protein results in increased secretion of Daunorubicin]
Benzbromarone affects the activity of ABCC1 protein
CTD PMID:9096673 PMID:9334814 PMID:15041471 PMID:16101123 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases activity
EXP
ISO
[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium
Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:19782883 PMID:19853032 PMID:22646477 PMID:31348918 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:31348918 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:31348918 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions
decreases activity
affects expression
ISO
EXP
Benzbromarone inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione]
Benzbromarone results in decreased activity of ABCC6 protein
Benzbromarone affects the expression of ABCC6 mRNA
CTD PMID:11880368 PMID:14667841 PMID:19483382 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression EXP Benzbromarone affects the expression of ABCG5 mRNA CTD PMID:19483382 NCBI chr 6:7,935,771...7,961,207
Ensembl chr 6:7,935,771...7,961,207
JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression EXP Benzbromarone affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 6:26,787,807...26,792,795
Ensembl chr 6:26,784,058...26,792,808
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression EXP Benzbromarone affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 8:115,149,638...115,154,556
Ensembl chr 8:115,150,514...115,154,550
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Benzbromarone affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr 7:11,992,543...12,000,978
Ensembl chr 7:11,992,543...11,998,973
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression EXP Benzbromarone affects the expression of ACACA mRNA CTD PMID:19483382 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Benzbromarone affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Aco1 aconitase 1 affects expression EXP Benzbromarone affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 5:56,425,076...56,481,218
Ensembl chr 5:56,425,024...56,481,218
JBrowse link
G Aco2 aconitase 2 affects expression EXP Benzbromarone affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression EXP Benzbromarone affects the expression of ACOT12 mRNA CTD PMID:19483382 NCBI chr 2:20,857,056...20,901,656
Ensembl chr 2:20,857,202...20,901,659
JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression EXP Benzbromarone affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr 6:107,517,668...107,522,952
Ensembl chr 6:107,517,668...107,522,952
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression EXP Benzbromarone affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 2:188,661,831...188,672,337
Ensembl chr 2:188,661,699...188,672,247
JBrowse link
G Add1 adducin 1 affects expression EXP Benzbromarone affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr14:81,367,466...81,426,610
Ensembl chr14:81,367,468...81,426,496
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Benzbromarone affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 2:243,702,035...243,720,063
Ensembl chr 2:243,700,784...243,740,899
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [Benzbromarone results in increased expression of ADIPOQ mRNA]
Benzbromarone results in increased expression of ADIPOQ protein
CTD PMID:19048458 PMID:21329621 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression EXP Benzbromarone affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr17:22,619,913...22,688,296
Ensembl chr17:22,619,891...22,688,307
JBrowse link
G Afm afamin affects expression EXP Benzbromarone affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr14:19,078,678...19,132,212
Ensembl chr14:19,078,680...19,132,208
JBrowse link
G Agt angiotensinogen affects expression EXP Benzbromarone affects the expression of AGT mRNA CTD PMID:19483382 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Benzbromarone affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 affects expression EXP Benzbromarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 5:135,482,068...135,498,693
Ensembl chr 5:135,482,068...135,498,822
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 decreases activity EXP Benzbromarone results in decreased activity of AKR1B8 protein CTD PMID:18845131 NCBI chr 4:61,772,064...61,784,637
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 decreases activity ISO Benzbromarone results in decreased activity of AKR1C4 protein CTD PMID:12604236 NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Benzbromarone results in decreased activity of AKR1C2 protein CTD PMID:12604236 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Benzbromarone results in decreased activity of AKR1C3 protein CTD PMID:12604236 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Benzbromarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 5:157,759,448...157,768,473
Ensembl chr 5:157,759,416...157,768,471
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Benzbromarone affects the expression of AKR7A3 mRNA CTD PMID:19483382 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Benzbromarone affects the expression of ALDH1A1 mRNA CTD PMID:19483382 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression EXP Benzbromarone affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Alkbh7 alkB homolog 7 affects expression EXP Benzbromarone affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr 9:10,045,375...10,047,507
Ensembl chr 9:10,045,375...10,047,507
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 affects expression EXP Benzbromarone affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr11:84,041,184...84,047,542
Ensembl chr11:84,041,184...84,047,546
JBrowse link
G Apcs amyloid P component, serum affects expression EXP Benzbromarone affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Benzbromarone affects the expression of APOA4 mRNA CTD PMID:19483382 NCBI chr 8:50,536,983...50,539,371
Ensembl chr 8:50,537,009...50,539,376
JBrowse link
G Apoh apolipoprotein H affects expression EXP Benzbromarone affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr10:96,640,013...96,653,939
Ensembl chr10:96,639,924...96,653,938
JBrowse link
G Apool apolipoprotein O-like affects expression EXP Benzbromarone affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:83,678,269...83,750,550
Ensembl chr  X:83,678,339...83,750,549
JBrowse link
G Arg1 arginase 1 affects expression EXP Benzbromarone affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 affects expression EXP Benzbromarone affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 1:187,770,160...187,779,675
Ensembl chr 1:187,770,160...187,779,675
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression EXP Benzbromarone affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr10:56,710,446...56,723,608
Ensembl chr10:56,710,464...56,723,611
JBrowse link
G Atf5 activating transcription factor 5 affects expression EXP Benzbromarone affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Benzbromarone affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 3:172,563,105...172,566,007
Ensembl chr 3:172,563,105...172,566,010
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression EXP Benzbromarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:11,137,889...11,164,854
Ensembl chr  X:11,136,939...11,164,915
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP Benzbromarone affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F affects expression EXP Benzbromarone affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 4:56,744,563...56,747,657
Ensembl chr 4:56,744,561...56,747,656
JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP Benzbromarone affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 5:64,768,397...64,777,368
Ensembl chr 5:64,768,401...64,777,368
JBrowse link
G Bcl6b BCL6B, transcription repressor affects expression EXP Benzbromarone affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr10:56,834,363...56,840,058
Ensembl chr10:56,834,364...56,839,437
JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP Benzbromarone affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 3:110,303,515...110,324,125
Ensembl chr 3:110,306,067...110,324,084
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression EXP Benzbromarone affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Btf3 basic transcription factor 3 affects expression EXP Benzbromarone affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 2:28,417,316...28,424,436
Ensembl chr 2:28,417,579...28,423,762
JBrowse link
G C1qbp complement C1q binding protein affects expression EXP Benzbromarone affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G C1s complement C1s affects expression EXP Benzbromarone affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 4:157,143,592...157,155,592
Ensembl chr 4:157,143,592...157,155,609
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression EXP Benzbromarone affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr11:38,354,746...38,420,133
Ensembl chr11:38,357,424...38,420,119
JBrowse link
G C4bpa complement component 4 binding protein, alpha affects expression EXP Benzbromarone affects the expression of C4BPA mRNA CTD PMID:19483382 NCBI chr13:47,342,090...47,377,580
Ensembl chr13:47,342,079...47,377,703
JBrowse link
G C7 complement C7 affects expression EXP Benzbromarone affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 2:54,707,621...54,781,624
Ensembl chr 2:54,709,138...54,777,729
JBrowse link
G C8b complement C8 beta chain affects expression EXP Benzbromarone affects the expression of C8B mRNA CTD PMID:19483382 NCBI chr 5:124,298,269...124,338,055
Ensembl chr 5:124,300,477...124,338,053
JBrowse link
G Ca3 carbonic anhydrase 3 affects expression EXP Benzbromarone affects the expression of CAR3 mRNA CTD PMID:19483382 NCBI chr 2:88,126,519...88,136,063
Ensembl chr 2:88,126,667...88,135,410
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects expression EXP Benzbromarone affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 4:50,326,447...50,861,161
Ensembl chr 4:50,326,442...50,860,756
JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression EXP Benzbromarone affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 3:93,701,830...93,789,580
Ensembl chr 3:93,702,487...93,789,617
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Benzbromarone affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Casp3 caspase 3 affects expression EXP Benzbromarone affects the expression of CASP3 mRNA CTD PMID:19483382 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase increases activity EXP Benzbromarone results in increased activity of CAT protein CTD PMID:2260096 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cbr1 carbonyl reductase 1 affects expression EXP Benzbromarone affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr11:33,813,041...33,815,418
Ensembl chr11:33,845,463...33,847,793
JBrowse link
G Cd36 CD36 molecule increases expression ISO Benzbromarone results in increased expression of CD36 mRNA CTD PMID:19048458 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Benzbromarone affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:40,702,027...40,716,901
Ensembl chr18:40,701,984...40,716,686
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 affects expression EXP Benzbromarone affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 2:209,118,140...209,162,071
Ensembl chr 2:209,118,922...209,160,653
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Benzbromarone affects the expression of CES2 mRNA CTD PMID:19483382 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Cfi complement factor I affects expression EXP Benzbromarone affects the expression of CFI mRNA CTD PMID:19483382 NCBI chr 2:235,264,149...235,305,779
Ensembl chr 2:235,264,219...235,305,781
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 affects expression EXP Benzbromarone affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 3:111,354,506...111,389,998
Ensembl chr 3:111,354,506...111,389,989
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression EXP Benzbromarone affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr20:18,493,538...18,506,923
Ensembl chr20:18,493,538...18,506,912
JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP Benzbromarone affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:25,016,177...25,082,563
Ensembl chr  X:25,016,401...25,080,410
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Benzbromarone affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr 9:10,048,715...10,056,068
Ensembl chr 9:10,048,886...10,054,359
JBrowse link
G Clptm1l CLPTM1-like affects expression EXP Benzbromarone affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 1:32,281,207...32,297,196
Ensembl chr 1:32,281,207...32,297,190
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression EXP Benzbromarone affects the expression of CMBL mRNA CTD PMID:19483382 NCBI chr 2:84,645,084...84,666,836
Ensembl chr 2:84,645,084...84,666,835
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression EXP Benzbromarone affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 5:133,759,722...133,786,452
Ensembl chr 5:133,759,735...133,786,452
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects expression EXP Benzbromarone affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 4:119,815,041...119,840,997
Ensembl chr 4:119,815,139...119,864,114
JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression EXP Benzbromarone affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr14:10,718,863...10,749,134
Ensembl chr14:10,718,844...10,749,120
JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression EXP Benzbromarone affects the expression of COQ3 mRNA CTD PMID:19483382 NCBI chr 5:36,024,673...36,056,664
Ensembl chr 5:36,024,649...36,056,669
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP Benzbromarone affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr19:54,245,958...54,252,198
Ensembl chr19:54,245,950...54,252,225
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression EXP Benzbromarone affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr 1:263,733,887...263,762,758
Ensembl chr 1:263,733,519...263,762,785
JBrowse link
G Cpq carboxypeptidase Q affects expression EXP Benzbromarone affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 7:71,709,174...72,167,413
Ensembl chr 7:71,709,157...72,167,417
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO Benzbromarone results in increased expression of CPT1A mRNA; Benzbromarone results in increased expression of CPT1A protein CTD PMID:25108121 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Benzbromarone affects the expression of CREM mRNA CTD PMID:19483382 NCBI chr17:57,021,704...57,090,888
Ensembl chr17:57,031,766...57,090,888
JBrowse link
G Crp C-reactive protein multiple interactions
decreases expression
ISO Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein]
Benzbromarone results in decreased expression of CRP protein
CTD PMID:21329621 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Csnk2b casein kinase 2 beta affects expression EXP Benzbromarone affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr20:5,108,692...5,113,675
Ensembl chr20:5,106,890...5,113,112
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression EXP Benzbromarone affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Ctnna1 catenin alpha 1 affects expression EXP Benzbromarone affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:27,923,229...28,055,972
Ensembl chr18:27,923,572...28,055,960
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression EXP Benzbromarone affects the expression of CYP2A1 mRNA CTD PMID:19483382 NCBI chr 1:83,711,223...83,725,222
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression EXP Benzbromarone affects the expression of CYP2B2 mRNA CTD PMID:19483382 NCBI chr 1:83,103,925...83,119,578
Ensembl chr 1:83,103,925...83,119,193
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression EXP Benzbromarone affects the expression of CYP2B3 mRNA CTD PMID:19483382 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO Benzbromarone analog binds to and results in decreased activity of CYP2C19 protein; Benzbromarone binds to and results in decreased activity of CYP2C19 protein CTD PMID:15615526 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 affects expression EXP Benzbromarone affects the expression of CYP2D3 mRNA CTD PMID:19483382 NCBI chr 7:123,634,400...123,638,757
Ensembl chr 7:123,625,590...123,638,765
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects expression EXP Benzbromarone affects the expression of CYP2D4 mRNA CTD PMID:19483382 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP Benzbromarone affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 affects expression EXP Benzbromarone affects the expression of CYP2J4 mRNA CTD PMID:19483382 NCBI chr 5:119,546,458...119,564,843
Ensembl chr 5:119,546,461...119,564,846
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 affects expression EXP Benzbromarone affects the expression of CYP2T1 mRNA CTD PMID:19483382 NCBI chr 1:83,965,370...83,969,466
Ensembl chr 1:83,965,608...83,969,559
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression EXP Benzbromarone affects the expression of CYP3A23-3A1 mRNA CTD PMID:19483382 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression EXP Benzbromarone affects the expression of CYP3A9 mRNA CTD PMID:19483382 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Benzbromarone affects the expression of CYP4A8 mRNA CTD PMID:19483382 NCBI chr 5:133,978,953...134,008,255
Ensembl chr 5:133,978,954...134,008,255
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 affects expression EXP Benzbromarone affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr 7:15,198,950...15,225,547
Ensembl chr 7:15,198,940...15,225,410
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein affects expression EXP Benzbromarone affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression EXP Benzbromarone affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr15:34,233,840...34,244,512
Ensembl chr15:34,234,193...34,244,504
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP Benzbromarone affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr10:109,906,119...109,909,696
Ensembl chr10:109,906,815...109,909,715
JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP Benzbromarone affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 5:29,573,893...29,601,731
Ensembl chr 5:29,573,898...29,601,748
JBrowse link
G Dexi Dexi homolog affects expression EXP Benzbromarone affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr10:5,199,226...5,211,913
Ensembl chr10:5,199,226...5,211,913
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression EXP Benzbromarone affects the expression of DGAT1 mRNA CTD PMID:19483382 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression EXP Benzbromarone affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression EXP Benzbromarone affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr15:34,155,043...34,167,073
Ensembl chr15:34,155,504...34,167,072
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression EXP Benzbromarone affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr10:47,065,755...47,111,089
Ensembl chr10:47,065,850...47,111,101
JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression EXP Benzbromarone affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr20:3,368,971...3,386,087
Ensembl chr20:3,367,150...3,386,106
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression EXP Benzbromarone affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr 6:92,057,782...92,076,022
Ensembl chr 6:92,057,807...92,076,021
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression EXP Benzbromarone affects the expression of DNAJC3 mRNA CTD PMID:19483382 NCBI chr15:104,186,918...104,226,236
Ensembl chr15:104,186,792...104,226,329
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP Benzbromarone affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression EXP Benzbromarone affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 2:221,823,692...222,694,627
Ensembl chr 2:221,823,687...222,694,627
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression EXP Benzbromarone affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 1:191,997,512...192,025,350
Ensembl chr 1:191,997,512...192,025,350
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects expression EXP Benzbromarone affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 1:212,570,213...212,579,040
Ensembl chr 1:212,570,195...212,579,057
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Benzbromarone affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr10:13,797,573...13,810,918
Ensembl chr10:13,797,562...13,810,913
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Benzbromarone affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr17:30,556,926...30,573,324
Ensembl chr17:30,556,884...30,639,040
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP Benzbromarone affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr 1:225,163,391...225,173,997
Ensembl chr 1:225,163,391...225,173,995
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression EXP Benzbromarone affects the expression of EHHADH mRNA CTD PMID:19483382 NCBI chr11:82,945,104...82,978,364
Ensembl chr11:82,945,104...82,978,364
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression EXP Benzbromarone affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr11:81,373,047...81,379,680
Ensembl chr11:81,373,048...81,379,871
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 affects expression EXP Benzbromarone affects the expression of EIF4EBP1 mRNA CTD PMID:19483382 NCBI chr16:68,954,860...68,968,248
Ensembl chr16:68,954,875...68,968,248
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression EXP Benzbromarone affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr12:25,093,119...25,109,805
Ensembl chr12:25,093,149...25,109,799
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP Benzbromarone affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Eno1 enolase 1 affects expression EXP Benzbromarone affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 5:167,288,223...167,299,610
Ensembl chr 5:167,288,223...167,299,609
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP Benzbromarone affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 2:233,667,253...233,743,866
Ensembl chr 2:233,667,254...233,743,866
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression EXP Benzbromarone affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 1:21,748,201...21,813,205
Ensembl chr 1:21,748,261...21,813,371
JBrowse link
G Epcam epithelial cell adhesion molecule affects expression EXP Benzbromarone affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 6:11,282,194...11,308,870
Ensembl chr 6:11,281,964...11,298,216
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Benzbromarone affects the expression of ERP29 mRNA CTD PMID:19483382 NCBI chr12:40,619,377...40,625,884
Ensembl chr12:40,619,377...40,625,883
JBrowse link
G Esd esterase D affects expression EXP Benzbromarone affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr15:56,756,848...56,776,348
Ensembl chr15:56,756,661...56,776,348
JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects expression EXP Benzbromarone affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 decreases activity ISO Benzbromarone results in decreased activity of EYA2 protein CTD PMID:22545090 NCBI chr 3:162,285,275...162,470,642
Ensembl chr 3:162,346,490...162,470,065
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 decreases activity ISO Benzbromarone results in decreased activity of EYA3 protein CTD PMID:22545090 NCBI chr 5:150,833,754...150,915,390
Ensembl chr 5:150,787,043...150,913,757
JBrowse link
G Faah fatty acid amide hydrolase affects expression EXP Benzbromarone affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 5:134,852,899...134,872,095
Ensembl chr 5:134,852,875...134,871,775
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Benzbromarone results in increased expression of FABP4 mRNA CTD PMID:19048458 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fads2 fatty acid desaturase 2 affects expression EXP Benzbromarone affects the expression of FADS2 mRNA CTD PMID:19483382 NCBI chr 1:225,906,582...226,152,568
Ensembl chr 1:226,114,413...226,152,524
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression EXP Benzbromarone affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression EXP Benzbromarone affects the expression of FDFT1 mRNA CTD PMID:19483382 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase affects expression EXP Benzbromarone affects the expression of FDPS mRNA CTD PMID:19483382 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Fdx2 ferredoxin 2 affects expression EXP Benzbromarone affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 8:22,086,534...22,091,450
Ensembl chr 8:22,086,534...22,091,450
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Benzbromarone affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr13:80,712,885...80,745,095
Ensembl chr13:80,712,882...80,745,347
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression EXP Benzbromarone affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr 7:12,314,848...12,317,998
Ensembl chr 7:12,314,848...12,317,998
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Benzbromarone affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression EXP Benzbromarone affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr11:7,210,169...7,485,895
Ensembl chr11:7,210,209...7,485,890
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression EXP Benzbromarone affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 3:110,975,923...110,979,957
Ensembl chr 3:110,975,923...110,979,957
JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression EXP Benzbromarone affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 5:34,040,258...34,063,369
Ensembl chr 5:34,040,258...34,063,361
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Benzbromarone affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:71,272,030...71,279,973
Ensembl chr  X:71,272,042...71,279,977
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression EXP Benzbromarone affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr17:42,085,027...42,131,344
Ensembl chr17:42,085,028...42,127,678
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Benzbromarone affects the expression of GPX1 mRNA CTD PMID:19483382 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression EXP Benzbromarone affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr 7:12,516,357...12,519,154
Ensembl chr 7:12,516,352...12,519,154
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Benzbromarone affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 7:117,304,742...117,307,916
Ensembl chr 7:117,304,742...117,307,916
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression EXP Benzbromarone affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr14:79,458,951...79,464,782
Ensembl chr14:79,458,963...79,464,770
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Benzbromarone affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr20:13,799,102...13,816,527
Ensembl chr20:13,799,102...13,816,526
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 affects expression EXP Benzbromarone affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 1:46,978,345...46,985,032
Ensembl chr 1:46,978,458...46,985,032
JBrowse link
G Gzma granzyme A affects expression EXP Benzbromarone affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G H3f3b H3.3 histone B affects expression EXP Benzbromarone affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr10:104,573,666...104,575,890
Ensembl chr10:104,573,664...104,575,890
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Benzbromarone affects the expression of HAL mRNA CTD PMID:19483382 NCBI chr 7:34,326,087...34,356,413
Ensembl chr 7:34,326,087...34,356,413
JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression EXP Benzbromarone affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 2:200,785,492...200,808,868
Ensembl chr 2:200,778,122...200,808,857
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression EXP Benzbromarone affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr10:15,589,364...15,590,207
Ensembl chr10:15,589,364...15,590,220
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Benzbromarone affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hdc histidine decarboxylase affects expression EXP Benzbromarone affects the expression of HDC mRNA CTD PMID:19483382 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression EXP Benzbromarone affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr11:65,983,221...66,034,555
Ensembl chr11:65,983,221...66,034,573
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 affects expression EXP Benzbromarone affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr11:36,474,028...36,479,947
Ensembl chr11:36,474,840...36,479,868
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression EXP Benzbromarone affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:158,196,640...158,228,815
Ensembl chr  X:158,197,149...158,228,749
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression EXP Benzbromarone affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 1:102,810,114...102,849,430
Ensembl chr 1:102,776,082...102,849,430
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Benzbromarone affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:44,810,462...44,897,677
Ensembl chr18:44,810,388...44,897,640
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression EXP Benzbromarone affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 5:76,812,881...76,848,853
Ensembl chr 5:76,812,931...76,848,101
JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression EXP Benzbromarone affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 1:201,499,067...201,548,508
Ensembl chr 1:201,499,028...201,548,513
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP Benzbromarone affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit affects expression EXP Benzbromarone affects the expression of IGFALS mRNA CTD PMID:19483382 NCBI chr10:14,240,308...14,243,554
Ensembl chr10:14,240,219...14,243,597
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Benzbromarone affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 9:80,118,029...80,144,804
Ensembl chr 9:80,118,029...80,144,789
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone CTD PMID:19362101 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein] CTD PMID:21329621 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone CTD PMID:19362101 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Impa1 inositol monophosphatase 1 affects expression EXP Benzbromarone affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 2:93,675,203...93,696,355
Ensembl chr 2:93,675,203...93,696,232
JBrowse link
G Inhbe inhibin subunit beta E affects expression EXP Benzbromarone affects the expression of INHBE mRNA CTD PMID:19483382 NCBI chr 7:70,641,423...70,642,848
Ensembl chr 7:70,640,075...70,643,169
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 affects expression EXP Benzbromarone affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr16:20,589,497...20,592,333
Ensembl chr16:20,589,481...20,592,449
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression EXP Benzbromarone affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr16:6,970,367...6,985,538
Ensembl chr16:6,970,342...6,985,579
JBrowse link
G Iyd iodotyrosine deiodinase decreases activity ISO Benzbromarone results in decreased activity of IYD protein CTD PMID:24012475 NCBI chr 1:40,086,513...40,100,966
Ensembl chr 1:40,086,470...40,101,840
JBrowse link
G Jak1 Janus kinase 1 affects expression EXP Benzbromarone affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 5:119,982,503...120,091,452
Ensembl chr 5:119,982,943...120,083,904
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression EXP Benzbromarone affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr12:13,192,452...13,210,758
Ensembl chr12:13,192,453...13,210,758
JBrowse link
G Kdr kinase insert domain receptor affects expression EXP Benzbromarone affects the expression of KDR mRNA CTD PMID:19483382 NCBI chr14:34,727,677...34,787,127
Ensembl chr14:34,727,623...34,787,183
JBrowse link
G Krt8 keratin 8 affects expression EXP Benzbromarone affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr 7:143,596,511...143,603,745
Ensembl chr 7:143,596,511...143,603,803
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression EXP Benzbromarone affects the expression of LCAT mRNA CTD PMID:19483382 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression EXP Benzbromarone affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 1:193,335,629...193,391,620
Ensembl chr 1:193,335,645...193,391,638
JBrowse link
G Lipc lipase C, hepatic type affects expression EXP Benzbromarone affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 8:77,272,582...77,398,485
Ensembl chr 8:77,272,570...77,398,248
JBrowse link
G Lox lysyl oxidase affects expression EXP Benzbromarone affects the expression of LOX mRNA CTD PMID:19483382 NCBI chr18:47,500,320...47,577,819
Ensembl chr18:47,500,330...47,577,819
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Benzbromarone results in increased expression of LPL protein CTD PMID:18274627 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP Benzbromarone affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 1:91,447,308...91,462,603
Ensembl chr 1:91,448,361...91,462,603
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 affects expression EXP Benzbromarone affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:26,196,797...26,216,981
Ensembl chr19:26,196,837...26,216,267
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Benzbromarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Masp2 MBL associated serine protease 2 affects expression EXP Benzbromarone affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 5:165,415,105...165,429,857
Ensembl chr 5:165,415,136...165,430,054
JBrowse link
G Me1 malic enzyme 1 affects expression EXP Benzbromarone affects the expression of ME1 mRNA CTD PMID:19483382 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression EXP Benzbromarone affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr 9:23,323,934...23,352,144
Ensembl chr 9:23,323,936...23,352,668
JBrowse link
G Mro maestro affects expression EXP Benzbromarone affects the expression of MRO mRNA CTD PMID:19483382 NCBI chr18:69,833,770...69,850,164 JBrowse link
G Mrpl2 mitochondrial ribosomal protein L2 affects expression EXP Benzbromarone affects the expression of MRPL2 mRNA CTD PMID:19483382 NCBI chr 9:16,643,621...16,647,394
Ensembl chr 9:16,643,619...16,647,458
JBrowse link
G mrpl9 mitochondrial ribosomal protein L9 affects expression EXP Benzbromarone affects the expression of MRPL9 mRNA CTD PMID:19483382 NCBI chr 2:195,684,750...195,689,470
Ensembl chr 2:195,684,210...195,689,052
JBrowse link
G Mug1 murinoglobulin 1 affects expression EXP Benzbromarone affects the expression of PZP mRNA CTD PMID:19483382 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Myadm myeloid-associated differentiation marker affects expression EXP Benzbromarone affects the expression of MYADM mRNA CTD PMID:19483382 NCBI chr 1:64,438,465...64,448,332
Ensembl chr 1:64,438,472...64,446,818
JBrowse link
G Mycbp2 MYC binding protein 2 affects expression EXP Benzbromarone affects the expression of MYCBP2 mRNA CTD PMID:19483382 NCBI chr15:87,405,472...87,450,812
NCBI chr15:93,678,062...93,901,556
Ensembl chr15:87,506,959...93,868,301
JBrowse link
G Myo1d myosin ID affects expression EXP Benzbromarone affects the expression of MYO1D mRNA CTD PMID:19483382 NCBI chr10:67,866,939...68,142,864
Ensembl chr10:67,866,940...68,142,864
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit affects expression EXP Benzbromarone affects the expression of NAA38 mRNA CTD PMID:19483382 NCBI chr10:55,997,614...55,998,691
Ensembl chr10:55,997,614...55,998,691
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects expression EXP Benzbromarone affects the expression of NAP1L1 mRNA CTD PMID:19483382 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nat8 N-acetyltransferase 8 affects expression EXP Benzbromarone affects the expression of NAT8 mRNA CTD PMID:19483382 NCBI chr 4:117,525,963...117,527,443 JBrowse link
G Ndrg2 NDRG family member 2 affects expression EXP Benzbromarone affects the expression of NDRG2 mRNA CTD PMID:19483382 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 affects expression EXP Benzbromarone affects the expression of NDUFS5 mRNA CTD PMID:19483382 NCBI chr 5:141,390,577...141,405,507
Ensembl chr 5:141,390,580...141,405,453
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 affects expression EXP Benzbromarone affects the expression of NDUFV3 mRNA CTD PMID:19483382 NCBI chr20:10,265,826...10,275,298
Ensembl chr20:10,265,806...10,275,304
JBrowse link
G Neu2 neuraminidase 2 affects expression EXP Benzbromarone affects the expression of NEU2 mRNA CTD PMID:19483382 NCBI chr 9:94,702,095...94,724,903
Ensembl chr 9:94,702,129...94,724,902
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 affects expression EXP Benzbromarone affects the expression of NFX1 mRNA CTD PMID:19483382 NCBI chr 5:57,290,916...57,348,720
Ensembl chr 5:57,291,156...57,348,720
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression EXP Benzbromarone affects the expression of NIPAL2 mRNA CTD PMID:19483382 NCBI chr 7:73,339,706...73,450,262
Ensembl chr 7:73,339,706...73,450,262
JBrowse link
G Nit1 nitrilase 1 affects expression EXP Benzbromarone affects the expression of NIT1 mRNA CTD PMID:19483382 NCBI chr13:89,722,370...89,725,806
Ensembl chr13:89,722,374...89,725,806
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP Benzbromarone affects the expression of NME2 mRNA CTD PMID:19483382 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression EXP Benzbromarone affects the expression of NR1I3 mRNA CTD PMID:19483382 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression EXP Benzbromarone affects the expression of NR3C1 mRNA CTD PMID:19483382 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Oaf out at first homolog affects expression EXP Benzbromarone affects the expression of OAF mRNA CTD PMID:19483382 NCBI chr 8:47,511,718...47,529,689
Ensembl chr 8:47,511,719...47,529,689
JBrowse link
G Obp3 alpha-2u globulin PGCL4 affects expression EXP Benzbromarone affects the expression of OBP3 mRNA CTD PMID:19483382 NCBI chr 5:77,313,357...77,316,875 JBrowse link
G Ogdh oxoglutarate dehydrogenase affects expression EXP Benzbromarone affects the expression of OGDH mRNA CTD PMID:19483382 NCBI chr14:86,414,924...86,481,903
Ensembl chr14:86,414,949...86,613,327
JBrowse link
G Olr59 olfactory receptor 59 affects expression EXP Benzbromarone affects the expression of OLR59 mRNA CTD PMID:19483382 NCBI chr 1:167,906,030...167,940,688
Ensembl chr 1:167,906,061...167,911,961
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit affects expression EXP Benzbromarone affects the expression of OSTC mRNA CTD PMID:19483382 NCBI chr 2:235,816,328...235,831,651
Ensembl chr 2:235,816,336...235,831,670
JBrowse link
G Otc ornithine transcarbamylase affects expression EXP Benzbromarone affects the expression of OTC mRNA CTD PMID:19483382 NCBI chr  X:13,524,804...13,601,074
Ensembl chr  X:13,524,607...13,601,069
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 affects expression EXP Benzbromarone affects the expression of PABPC4 mRNA CTD PMID:19483382 NCBI chr 5:140,978,893...140,994,732
Ensembl chr 5:140,979,435...140,994,732
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase affects expression EXP Benzbromarone affects the expression of PAICS mRNA CTD PMID:19483382 NCBI chr14:33,563,884...33,580,944
Ensembl chr14:33,563,886...33,580,566
JBrowse link
G Pc pyruvate carboxylase affects expression EXP Benzbromarone affects the expression of PCX mRNA CTD PMID:19483382 NCBI chr 1:219,759,157...219,859,854
Ensembl chr 1:219,759,183...219,859,848
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta affects expression EXP Benzbromarone affects the expression of PCCB mRNA CTD PMID:19483382 NCBI chr 8:109,368,887...109,418,871
Ensembl chr 8:109,368,624...109,418,872
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 affects expression EXP Benzbromarone affects the expression of PCSK6 mRNA CTD PMID:19483382 NCBI chr 1:126,749,508...126,947,392
Ensembl chr 1:126,749,508...126,947,392
JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression EXP Benzbromarone affects the expression of PCTP mRNA CTD PMID:19483382 NCBI chr10:77,491,445...77,537,268
Ensembl chr10:77,491,454...77,512,032
JBrowse link
G Pdcl3 phosducin-like 3 affects expression EXP Benzbromarone affects the expression of PDCL3 mRNA CTD PMID:19483382 NCBI chr 9:45,672,257...45,680,728
Ensembl chr 9:45,672,157...45,680,799
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP Benzbromarone affects the expression of PDIA3 mRNA CTD PMID:19483382 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 affects expression EXP Benzbromarone affects the expression of PDIA6 mRNA CTD PMID:19483382 NCBI chr 6:42,568,269...42,585,654
Ensembl chr 6:42,568,220...42,585,652
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 affects expression EXP Benzbromarone affects the expression of PEX19 mRNA CTD PMID:19483382 NCBI chr13:90,514,324...90,530,825
Ensembl chr13:90,514,336...90,530,349
JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression EXP Benzbromarone affects the expression of PGAM1 mRNA CTD PMID:19483382 NCBI chr 1:261,158,204...261,165,814
Ensembl chr 1:261,158,261...261,165,808
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects expression EXP Benzbromarone affects the expression of PGRMC1 mRNA CTD PMID:19483382 NCBI chr  X:123,205,869...123,213,880
Ensembl chr  X:123,205,869...123,213,882
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase affects expression EXP Benzbromarone affects the expression of PHYH mRNA CTD PMID:19483382 NCBI chr17:77,287,580...77,304,482
Ensembl chr17:77,287,188...77,304,530
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P affects expression EXP Benzbromarone affects the expression of PIGP mRNA CTD PMID:19483382 NCBI chr11:34,592,128...34,598,253
Ensembl chr11:34,592,121...34,598,275
JBrowse link
G Pklr pyruvate kinase L/R affects expression EXP Benzbromarone affects the expression of PKLR mRNA CTD PMID:19483382 NCBI chr 2:188,449,158...188,458,034
Ensembl chr 2:188,449,210...188,459,592
JBrowse link
G Plbd1 phospholipase B domain containing 1 affects expression EXP Benzbromarone affects the expression of PLBD1 mRNA CTD PMID:19483382 NCBI chr 4:170,564,387...170,620,681
Ensembl chr 4:170,564,367...170,620,703
JBrowse link
G Plg plasminogen affects expression EXP Benzbromarone affects the expression of PLG mRNA CTD PMID:19483382 NCBI chr 1:48,521,828...48,563,895
Ensembl chr 1:48,521,772...48,563,776
JBrowse link
G Pls3 plastin 3 affects expression EXP Benzbromarone affects the expression of PLS3 mRNA CTD PMID:19483382 NCBI chr  X:119,030,311...119,124,268
Ensembl chr  X:119,030,419...119,124,250
JBrowse link
G Pon2 paraoxonase 2 affects expression EXP Benzbromarone affects the expression of PON2 mRNA CTD PMID:19483382 NCBI chr 4:30,344,705...30,380,119
Ensembl chr 4:30,344,709...30,380,119
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression ISO Benzbromarone affects the expression of PPARG mRNA CTD PMID:19048458 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor affects expression EXP Benzbromarone affects the expression of PPDPF mRNA CTD PMID:19483382 NCBI chr 3:176,690,507...176,692,272
Ensembl chr 3:176,691,329...176,692,271
JBrowse link
G Prdx2 peroxiredoxin 2 affects expression EXP Benzbromarone affects the expression of PRDX2 mRNA CTD PMID:19483382 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Prdx6 peroxiredoxin 6 affects expression EXP Benzbromarone affects the expression of PRDX6 mRNA CTD PMID:19483382 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa affects expression EXP Benzbromarone affects the expression of PROC mRNA CTD PMID:19483382 NCBI chr18:24,918,402...24,928,822
Ensembl chr18:24,918,398...24,929,091
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 affects expression EXP Benzbromarone affects the expression of PRPSAP1 mRNA CTD PMID:19483382 NCBI chr10:105,430,516...105,492,154
Ensembl chr10:105,430,520...105,452,228
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 affects expression EXP Benzbromarone affects the expression of PSMA6 mRNA CTD PMID:19483382 NCBI chr 6:76,174,460...76,205,429
Ensembl chr 6:76,174,452...76,205,426
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects expression EXP Benzbromarone affects the expression of PSMB1 mRNA CTD PMID:19483382 NCBI chr 1:57,470,878...57,491,359
Ensembl chr 1:57,470,632...57,489,727
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 affects expression EXP Benzbromarone affects the expression of PSMB3 mRNA CTD PMID:19483382 NCBI chr10:85,646,646...85,653,729
Ensembl chr10:85,646,633...85,653,729
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 affects expression EXP Benzbromarone affects the expression of PSMC1 mRNA CTD PMID:19483382 NCBI chr 6:124,123,283...124,135,644
Ensembl chr 6:124,123,228...124,135,658
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 affects expression EXP Benzbromarone affects the expression of PSMC3 mRNA CTD PMID:19483382 NCBI chr 3:79,876,938...79,882,319
Ensembl chr 3:79,876,938...79,882,319
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 affects expression EXP Benzbromarone affects the expression of PSMC5 mRNA CTD PMID:19483382 NCBI chr10:94,445,877...94,451,811
Ensembl chr10:94,445,877...94,451,811
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 affects expression EXP Benzbromarone affects the expression of PSMD1 mRNA CTD PMID:19483382 NCBI chr 9:93,080,618...93,155,033
Ensembl chr 9:93,080,615...93,155,027
JBrowse link
G Psmd4 proteasome 26S subunit, non-ATPase 4 affects expression EXP Benzbromarone affects the expression of PSMD4 mRNA CTD PMID:19483382 NCBI chr 2:196,198,303...196,207,569
Ensembl chr 2:196,198,038...196,207,560
JBrowse link
G Ptms parathymosin affects expression EXP Benzbromarone affects the expression of PTMS mRNA CTD PMID:19483382 NCBI chr 4:157,435,371...157,439,507
Ensembl chr 4:157,435,373...157,439,507
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F affects expression EXP Benzbromarone affects the expression of PTPRF mRNA CTD PMID:19483382 NCBI chr 5:137,036,936...137,112,930
Ensembl chr 5:137,036,935...137,112,927
JBrowse link
G Pttg1ip PTTG1 interacting protein affects expression EXP Benzbromarone affects the expression of PTTG1IP mRNA CTD PMID:19483382 NCBI chr20:11,746,369...11,764,097
Ensembl chr20:11,746,370...11,764,233
JBrowse link
G Pygl glycogen phosphorylase L affects expression EXP Benzbromarone affects the expression of PYGL mRNA CTD PMID:19483382 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Rab5if RAB5 interacting factor affects expression EXP Benzbromarone affects the expression of RAB5IF mRNA CTD PMID:19483382 NCBI chr 3:152,933,771...152,943,780
Ensembl chr 3:152,933,771...152,943,777
JBrowse link
G Rida reactive intermediate imine deaminase A homolog affects expression EXP Benzbromarone affects the expression of RIDA mRNA CTD PMID:19483382 NCBI chr 7:73,256,506...73,270,308
Ensembl chr 7:73,256,508...73,270,308
JBrowse link
G Rnase4 ribonuclease A family member 4 affects expression EXP Benzbromarone affects the expression of RNASE4 mRNA CTD PMID:19483382 NCBI chr15:28,018,040...28,035,395
Ensembl chr15:28,018,040...28,035,389
Ensembl chr15:28,018,040...28,035,389
JBrowse link
G Rnf103 ring finger protein 103 affects expression EXP Benzbromarone affects the expression of RNF103 mRNA CTD PMID:19483382 NCBI chr 4:99,398,479...99,415,193
Ensembl chr 4:99,398,494...99,421,164
JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 affects expression EXP Benzbromarone affects the expression of RNPS1 mRNA CTD PMID:19483382 NCBI chr10:13,786,339...13,796,720
Ensembl chr10:13,786,459...13,796,717
JBrowse link
G Rpl11 ribosomal protein L11 affects expression EXP Benzbromarone affects the expression of RPL11 mRNA CTD PMID:19483382 NCBI chr 5:154,390,809...154,394,412
Ensembl chr 5:154,388,140...154,394,328
JBrowse link
G Rpl13 ribosomal protein L13 affects expression EXP Benzbromarone affects the expression of RPL13 mRNA CTD PMID:19483382 NCBI chr19:55,917,489...55,920,040
Ensembl chr19:55,917,736...55,919,996
JBrowse link
G Rpl15 ribosomal protein L15 affects expression EXP Benzbromarone affects the expression of RPL15 mRNA CTD PMID:19483382 NCBI chr15:8,188,717...8,192,153
Ensembl chr15:8,189,253...8,192,152
JBrowse link
G Rpl17 ribosomal protein L17 affects expression EXP Benzbromarone affects the expression of RPL17 mRNA CTD PMID:19483382 NCBI chr18:70,969,733...70,972,839
Ensembl chr18:70,970,596...70,975,494
JBrowse link
G Rpl23 ribosomal protein L23 affects expression EXP Benzbromarone affects the expression of RPL23 mRNA CTD PMID:19483382 NCBI chr10:85,721,398...85,725,359
Ensembl chr10:85,721,394...85,725,429
JBrowse link
G Rpl3 ribosomal protein L3 affects expression EXP Benzbromarone affects the expression of RPL3 mRNA CTD PMID:19483382 NCBI chr 7:121,297,365...121,302,739
Ensembl chr 7:121,297,355...121,311,565
JBrowse link
G Rpl32 ribosomal protein L32 affects expression EXP Benzbromarone affects the expression of RPL32 mRNA CTD PMID:19483382 NCBI chr 4:147,715,480...147,719,044
Ensembl chr 6:145,777,318...145,777,767
Ensembl chr 4:145,777,318...145,777,767
JBrowse link
G Rpl4 ribosomal protein L4 affects expression EXP Benzbromarone affects the expression of RPL4 mRNA CTD PMID:19483382 NCBI chr 8:69,121,682...69,126,805
Ensembl chr 8:69,121,682...69,126,805
JBrowse link
G Rpn2 ribophorin II affects expression EXP Benzbromarone affects the expression of RPN2 mRNA CTD PMID:19483382 NCBI chr 3:153,398,373...153,445,633
Ensembl chr 3:153,398,130...153,445,632
JBrowse link
G Rps14 ribosomal protein S14 affects expression EXP Benzbromarone affects the expression of RPS14 mRNA CTD PMID:19483382 NCBI chr18:56,042,532...56,047,316
Ensembl chr18:56,044,369...56,047,316
JBrowse link
G Rps18 ribosomal protein S18 affects expression EXP Benzbromarone affects the expression of RPS18 mRNA CTD PMID:19483382 NCBI chr20:5,441,875...5,445,553
Ensembl chr20:5,441,876...5,445,553
JBrowse link
G Rps19 ribosomal protein S19 affects expression EXP Benzbromarone affects the expression of RPS19 mRNA CTD PMID:19483382 NCBI chr 1:81,750,873...81,756,629
Ensembl chr 1:81,750,928...81,756,627
JBrowse link
G Rps20 ribosomal protein S20 affects expression EXP Benzbromarone affects the expression of RPS20 mRNA CTD PMID:19483382 NCBI chr 5:16,706,052...16,707,214
Ensembl chr 5:16,706,082...16,706,909
JBrowse link
G Rps3a ribosomal protein S3a affects expression EXP Benzbromarone affects the expression of RPS3A mRNA CTD PMID:19483382 NCBI chr 2:185,440,477...185,444,846
Ensembl chr 2:185,440,291...185,444,897
JBrowse link
G Rps6 ribosomal protein S6 affects expression EXP Benzbromarone affects the expression of RPS6 mRNA CTD PMID:19483382 NCBI chr 5:105,197,821...105,200,681
Ensembl chr 5:105,197,857...105,200,148
JBrowse link
G Rps8 ribosomal protein S8 affects expression EXP Benzbromarone affects the expression of RPS8 mRNA CTD PMID:19483382 NCBI chr 5:136,020,941...136,023,511
Ensembl chr 5:136,020,941...136,023,511
JBrowse link
G Rras2 RAS related 2 affects expression EXP Benzbromarone affects the expression of RRAS2 mRNA CTD PMID:19483382 NCBI chr 1:178,940,515...179,010,257
Ensembl chr 1:178,940,516...179,010,257
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression EXP Benzbromarone affects the expression of RT1-S3 mRNA CTD PMID:19483382 NCBI chr20:3,176,124...3,180,825
Ensembl chr20:3,176,107...3,179,818
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression EXP Benzbromarone affects the expression of S1PR1 mRNA CTD PMID:19483382 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression EXP Benzbromarone affects the expression of SBSPON mRNA CTD PMID:19483382 NCBI chr 5:2,813,004...2,847,697
Ensembl chr 5:2,813,131...2,843,483
JBrowse link
G Sdc2 syndecan 2 affects expression EXP Benzbromarone affects the expression of SDC2 mRNA CTD PMID:19483382 NCBI chr 7:71,572,731...71,686,139
Ensembl chr 7:71,572,941...71,686,044
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C affects expression EXP Benzbromarone affects the expression of SDHC mRNA CTD PMID:19483382 NCBI chr13:89,498,047...89,518,979
Ensembl chr13:89,498,048...89,518,939
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D affects expression EXP Benzbromarone affects the expression of SDHD mRNA CTD PMID:19483382 NCBI chr 8:55,028,125...55,037,604
Ensembl chr 8:55,028,125...55,037,604
JBrowse link
G Serinc3 serine incorporator 3 affects expression EXP Benzbromarone affects the expression of SERINC3 mRNA CTD PMID:19483382 NCBI chr 3:160,018,643...160,038,078
Ensembl chr 3:160,018,646...160,038,078
JBrowse link
G Serpina1 serpin family A member 1 affects expression EXP Benzbromarone affects the expression of SERPINA1 mRNA CTD PMID:19483382 NCBI chr 6:127,610,241...127,632,265
Ensembl chr 6:127,610,243...127,632,265
JBrowse link
G Serpina10 serpin family A member 10 affects expression EXP Benzbromarone affects the expression of SERPINA10 mRNA CTD PMID:19483382 NCBI chr 6:127,500,014...127,508,470
Ensembl chr 6:127,500,016...127,508,452
JBrowse link
G Serpina4 serpin family A member 4 affects expression EXP Benzbromarone affects the expression of SERPINA4 mRNA CTD PMID:19483382 NCBI chr 6:127,743,883...127,753,047
Ensembl chr 6:127,743,971...127,753,046
JBrowse link
G Serpinf2 serpin family F member 2 affects expression EXP Benzbromarone affects the expression of SERPINF2 mRNA CTD PMID:19483382 NCBI chr10:62,264,247...62,272,353
Ensembl chr10:62,264,788...62,273,119
JBrowse link
G Sfxn1 sideroflexin 1 affects expression EXP Benzbromarone affects the expression of SFXN1 mRNA CTD PMID:19483382 NCBI chr17:11,046,588...11,082,219
Ensembl chr17:11,045,761...11,082,047
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 affects expression EXP Benzbromarone affects the expression of SHMT2 mRNA CTD PMID:19483382 NCBI chr 7:70,824,718...70,829,822
Ensembl chr 7:70,824,715...70,829,815
JBrowse link
G Slc22a1 solute carrier family 22 member 1 affects expression EXP Benzbromarone affects the expression of SLC22A1 mRNA CTD PMID:19483382 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a12 solute carrier family 22 member 12 affects activity
decreases activity
multiple interactions
affects response to substance
ISO
EXP
Benzbromarone affects the activity of SLC22A12 protein
Benzbromarone results in decreased activity of SLC22A12 protein
Benzbromarone inhibits the reaction [SLC22A12 protein affects the transport of Uric Acid]
SLC22A12 protein affects the susceptibility to Benzbromarone
Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Oxypurinol]; Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid]
CTD PMID:14694169 PMID:14747372 PMID:16135657 PMID:18670416 PMID:20486468 PMID:21074513 PMID:21272127 PMID:21449597 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Benzbromarone inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc23a1 solute carrier family 23 member 1 affects expression EXP Benzbromarone affects the expression of SLC23A1 mRNA CTD PMID:19483382 NCBI chr18:28,413,910...28,428,133
Ensembl chr18:28,414,009...28,428,117
JBrowse link
G Slc25a13 solute carrier family 25 member 13 affects expression EXP Benzbromarone affects the expression of SLC25A13 mRNA CTD PMID:19483382 NCBI chr 4:31,134,165...31,757,006
Ensembl chr 4:31,608,269...31,730,386
JBrowse link
G Slc25a3 solute carrier family 25 member 3 affects expression EXP Benzbromarone affects the expression of SLC25A3 mRNA CTD PMID:19483382 NCBI chr 7:31,816,601...31,824,064
Ensembl chr 7:31,816,602...31,824,071
JBrowse link
G Slc27a2 solute carrier family 27 member 2 affects expression EXP Benzbromarone affects the expression of SLC27A2 mRNA CTD PMID:19483382 NCBI chr 3:119,014,620...119,052,531
Ensembl chr 3:119,014,620...119,052,531
JBrowse link
G Slc2a9 solute carrier family 2 member 9 multiple interactions ISO Benzbromarone inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid]
Benzbromarone inhibits the reaction [SLC2A9 protein alternative form results in increased transport of Uric Acid]
CTD PMID:18842065 PMID:19587147 NCBI chr14:77,067,537...77,192,702
Ensembl chr14:77,067,503...77,192,702
JBrowse link
G Slc39a8 solute carrier family 39 member 8 affects expression EXP Benzbromarone affects the expression of SLC39A8 mRNA CTD PMID:19483382 NCBI chr 2:241,028,851...241,092,584
Ensembl chr 2:241,029,693...241,092,582
JBrowse link
G Slc46a1 solute carrier family 46 member 1 affects expression EXP Benzbromarone affects the expression of SLC46A1 mRNA CTD PMID:19483382 NCBI chr10:65,728,508...65,741,708
Ensembl chr10:65,733,991...65,740,828
JBrowse link
G Slc66a2 solute carrier family 66 member 2 affects expression EXP Benzbromarone affects the expression of SLC66A2 mRNA CTD PMID:19483382 NCBI chr18:76,768,466...76,805,773
Ensembl chr18:76,770,012...76,805,766
JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression EXP Benzbromarone affects the expression of SLC6A6 mRNA CTD PMID:19483382 NCBI chr 4:123,638,619...123,713,469
Ensembl chr 4:123,642,210...123,713,464
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Benzbromarone results in increased expression of SOD2 mRNA CTD PMID:25108121 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sppl2a signal peptide peptidase-like 2A affects expression EXP Benzbromarone affects the expression of SPPL2A mRNA CTD PMID:19483382 NCBI chr 3:119,361,651...119,405,453
Ensembl chr 3:119,361,655...119,405,453
JBrowse link
G Srm spermidine synthase affects expression EXP Benzbromarone affects the expression of SRM mRNA CTD PMID:19483382 NCBI chr 5:165,405,168...165,408,325
Ensembl chr 5:165,405,168...165,408,320
JBrowse link
G Srprb SRP receptor subunit beta affects expression EXP Benzbromarone affects the expression of SRPRB mRNA CTD PMID:19483382 NCBI chr 8:111,673,479...111,687,426 JBrowse link
G Ssx2ip SSX family member 2 interacting protein affects expression EXP Benzbromarone affects the expression of SSX2IP mRNA CTD PMID:19483382 NCBI chr 2:252,263,323...252,296,049
Ensembl chr 2:252,263,386...252,296,051
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression EXP Benzbromarone affects the expression of ST3GAL6 mRNA CTD PMID:19483382 NCBI chr11:44,176,518...44,237,119
Ensembl chr11:44,192,940...44,237,100
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 affects expression EXP Benzbromarone affects the expression of ST6GAL1 mRNA CTD PMID:19483382 NCBI chr11:80,927,601...80,981,424
Ensembl chr11:80,927,601...80,981,422
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects expression EXP Benzbromarone affects the expression of SUCLG1 mRNA CTD PMID:19483382 NCBI chr 4:101,181,315...101,210,692
Ensembl chr 4:101,180,404...101,210,746
JBrowse link
G Surf4 surfeit 4 affects expression EXP Benzbromarone affects the expression of SURF4 mRNA CTD PMID:19483382 NCBI chr 3:5,468,284...5,481,447
Ensembl chr 3:5,461,770...5,483,239
JBrowse link
G Synj2bp synaptojanin 2 binding protein affects expression EXP Benzbromarone affects the expression of SYNJ2BP mRNA CTD PMID:19483382 NCBI chr 6:105,224,166...105,261,549
Ensembl chr 6:105,224,166...105,261,549
JBrowse link
G Tgfbi transforming growth factor, beta induced affects expression EXP Benzbromarone affects the expression of TGFBI mRNA CTD PMID:19483382 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338
JBrowse link
G Thnsl2 threonine synthase-like 2 affects expression EXP Benzbromarone affects the expression of THNSL2 mRNA CTD PMID:19483382 NCBI chr 4:98,976,559...98,997,187
Ensembl chr 4:98,976,550...98,995,590
JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 affects expression EXP Benzbromarone affects the expression of TIMM21 mRNA CTD PMID:19483382 NCBI chr18:81,803,165...81,807,627
Ensembl chr18:81,803,173...81,807,627
JBrowse link
G Tkfc triokinase and FMN cyclase affects expression EXP Benzbromarone affects the expression of TKFC mRNA CTD PMID:19483382 NCBI chr 1:226,642,901...226,657,698
Ensembl chr 1:226,644,200...226,657,408
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression EXP Benzbromarone affects the expression of TMBIM1 mRNA CTD PMID:19483382 NCBI chr 9:81,569,289...81,586,469
Ensembl chr 9:81,569,289...81,586,553
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 affects expression EXP Benzbromarone affects the expression of TMCO1 mRNA CTD PMID:19483382 NCBI chr13:85,465,015...85,559,113
Ensembl chr13:85,465,792...85,559,087
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 affects expression EXP Benzbromarone affects the expression of TMED2 mRNA CTD PMID:19483382 NCBI chr12:37,471,259...37,480,344
Ensembl chr12:37,471,260...37,480,297
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 affects expression EXP Benzbromarone affects the expression of TMED7 mRNA CTD PMID:19483382 NCBI chr18:40,579,182...40,586,260
Ensembl chr18:40,579,182...40,586,260
JBrowse link
G Tmem123 transmembrane protein 123 affects expression EXP Benzbromarone affects the expression of TMEM123 mRNA CTD PMID:19483382 NCBI chr 8:5,967,373...5,997,387
Ensembl chr 8:5,967,463...5,997,383
JBrowse link
G Tmem97 transmembrane protein 97 affects expression EXP Benzbromarone affects the expression of TMEM97 mRNA CTD PMID:19483382 NCBI chr10:65,811,455...65,820,538
Ensembl chr10:65,811,456...65,820,538
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO Benzbromarone results in increased expression of TNF protein
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD PMID:19362101 PMID:19933411 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Txn1 thioredoxin 1 affects expression EXP Benzbromarone affects the expression of TXN1 mRNA CTD PMID:19483382 NCBI chr 5:75,049,735...75,057,731
Ensembl chr 5:75,049,747...75,057,752
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression EXP Benzbromarone affects the expression of TXNL1 mRNA CTD PMID:19483382 NCBI chr18:59,056,454...59,086,278
Ensembl chr18:59,059,375...59,086,256
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression EXP Benzbromarone affects the expression of UBA52 mRNA CTD PMID:19483382 NCBI chr16:20,668,925...20,671,127
Ensembl chr16:20,668,971...20,671,127
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression EXP Benzbromarone affects the expression of UBE2N mRNA CTD PMID:19483382 NCBI chr 7:36,610,147...36,640,190
Ensembl chr 7:36,610,147...36,640,189
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 affects expression EXP Benzbromarone affects the expression of UFD1 mRNA CTD PMID:19483382 NCBI chr11:86,304,836...86,328,478
Ensembl chr11:86,304,815...86,328,469
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression EXP Benzbromarone affects the expression of UGT1A1 mRNA CTD PMID:19483382 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Uhrf1bp1l UHRF1 binding protein 1-like affects expression EXP Benzbromarone affects the expression of UHRF1BP1L mRNA CTD PMID:19483382 NCBI chr 7:30,408,519...30,455,783
Ensembl chr 7:30,408,519...30,455,783
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression EXP Benzbromarone affects the expression of UQCR11 mRNA CTD PMID:19483382 NCBI chr 7:12,171,146...12,175,838
Ensembl chr 7:12,171,185...12,175,835
JBrowse link
G Vnn1 vanin 1 affects expression EXP Benzbromarone affects the expression of VNN1 mRNA CTD PMID:19483382 NCBI chr 1:22,614,832...22,625,134
Ensembl chr 1:22,614,783...22,625,204
JBrowse link
G Wdr26 WD repeat domain 26 affects expression EXP Benzbromarone affects the expression of WDR26 mRNA CTD PMID:19483382 NCBI chr13:99,493,117...99,532,775
Ensembl chr13:99,493,120...99,531,959
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma affects expression EXP Benzbromarone affects the expression of YWHAG mRNA CTD PMID:19483382 NCBI chr12:23,789,547...23,817,884
Ensembl chr12:23,789,638...23,817,883
JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 affects expression EXP Benzbromarone affects the expression of ZDHHC23 mRNA CTD PMID:19483382 NCBI chr11:61,661,119...61,677,547
Ensembl chr11:61,661,310...61,676,684
JBrowse link
G Zwint ZW10 interacting kinetochore protein affects expression EXP Benzbromarone affects the expression of ZWINT mRNA CTD PMID:19483382 NCBI chr20:17,075,781...17,091,715
Ensembl chr20:17,075,771...17,091,766
JBrowse link
desmopressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 increases expression
multiple interactions
ISO
EXP
Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA; Deamino Arginine Vasopressin results in increased expression of AQP2 protein
Deamino Arginine Vasopressin inhibits the reaction [aluminum lactate results in decreased expression of AQP2 protein]; Deamino Arginine Vasopressin results in increased expression of and results in increased uptake of and results in increased ubiquitination of AQP2 protein
Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]
CTD PMID:16495377 PMID:16675087 PMID:21734099 NCBI chr 7:141,237,802...141,242,837
Ensembl chr 7:141,237,768...141,245,165
JBrowse link
G Avpr2 arginine vasopressin receptor 2 multiple interactions EXP
ISO
[Deamino Arginine Vasopressin binds to and results in increased activity of AVPR2 protein] which results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid CTD PMID:1399968 PMID:15685210 NCBI chr  X:156,889,006...156,892,707
Ensembl chr  X:156,889,410...156,891,213
JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO Deamino Arginine Vasopressin results in increased activity of CFTR protein CTD PMID:15685210 NCBI chr 4:42,693,263...42,860,679
Ensembl chr 4:42,692,836...42,860,676
JBrowse link
G Cul5 cullin 5 increases expression EXP Deamino Arginine Vasopressin results in increased expression of CUL5 protein CTD PMID:21734099 NCBI chr 8:58,199,992...58,255,149
Ensembl chr 8:58,202,821...58,253,688
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation
multiple interactions
EXP Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein
ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein]
CTD PMID:15347643 NCBI chr 3:152,857,573...152,863,961
Ensembl chr 3:152,857,592...152,863,960
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression EXP Deamino Arginine Vasopressin results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1B mRNA CTD PMID:11711512 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1G mRNA CTD PMID:11711512 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268
JBrowse link
G Vwf von Willebrand factor increases activity
increases secretion
ISO Deamino Arginine Vasopressin results in increased activity of VWF protein
Deamino Arginine Vasopressin results in increased secretion of VWF protein
CTD PMID:1837767 PMID:2738447 PMID:3259400 NCBI chr 4:158,085,059...158,219,525
Ensembl chr 4:158,088,505...158,219,523
JBrowse link
E3040 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of E 3040 analog CTD PMID:19628752 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects export ISO ABCG2 protein affects the export of E 3040 analog CTD PMID:15598971 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO E 3040 inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid] CTD PMID:21272127 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
nitroxoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:31638783 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Cat catalase multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAT protein] CTD PMID:31638783 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of and affects the localization of FOXO3 protein]; nitroxoline results in decreased expression of and affects the localization of FOXO3 protein CTD PMID:31638783 NCBI chr20:46,428,078...46,519,156
Ensembl chr20:46,428,124...46,519,144
JBrowse link
G Metap2 methionyl aminopeptidase 2 decreases activity ISO nitroxoline results in decreased activity of METAP2 protein CTD PMID:21088277 NCBI chr 7:34,762,241...34,789,456
Ensembl chr 7:34,762,231...34,789,479
JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression
ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]
nitroxoline results in decreased expression of SIRT1 protein
CTD PMID:31638783 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of SOD1 protein] CTD PMID:31638783 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of SOD2 protein] CTD PMID:31638783 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
probenecid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO Probenecid inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide] CTD PMID:12379217 NCBI chr10:98,236,919...98,308,288
Ensembl chr10:98,237,141...98,294,522
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
affects activity
EXP
ISO
Probenecid results in decreased activity of ABCC1 protein
[Probenecid results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine
Probenecid affects the activity of ABCC1 protein
[Probenecid results in decreased activity of ABCC1 protein] which results in decreased export of 10-nitro-oleic acid metabolite; Probenecid affects the reaction [ABCC1 protein results in increased transport of Valproic Acid]; Probenecid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]
CTD PMID:9096673 PMID:9334814 PMID:12893836 PMID:15066675 PMID:15585369 PMID:15652236 PMID:15804283 PMID:15916776 PMID:16101123 PMID:29158255 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases export
multiple interactions
increases activity
EXP
ISO
ABCC2 protein results in increased export of Probenecid
Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein]; Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]; Probenecid promotes the reaction [ABCC2 protein affects the transport of docetaxel]; Probenecid promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Probenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]; Probenecid promotes the reaction [ABCC2 protein affects the transport of Paclitaxel]; Probenecid promotes the reaction [ABCC2 protein affects the transport of Vinblastine]; Probenecid promotes the reaction [ABCC2 protein results in decreased susceptibility to Paclitaxel]
[Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite; [Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium
Probenecid results in increased activity of ABCC2 protein
CTD PMID:11477083 PMID:12608533 PMID:12704183 PMID:15849751 PMID:15904671 PMID:17478601 PMID:19853032 PMID:20089784 PMID:27450509 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Probenecid inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide] CTD PMID:12704183 NCBI chr10:82,047,308...82,116,928
Ensembl chr10:82,047,863...82,117,109
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO Probenecid inhibits the reaction [ABCC4 protein results in increased transport of Cyclic GMP]
Probenecid affects the reaction [ABCC4 protein affects the uptake of Cyclic AMP analog]
CTD PMID:11856762 PMID:28587784 NCBI chr15:103,695,415...103,927,980
Ensembl chr15:103,696,557...103,927,592
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO Probenecid inhibits the reaction [ABCC5 protein results in decreased susceptibility to Thioguanine] CTD PMID:15897250 NCBI chr11:84,395,982...84,490,215
Ensembl chr11:84,396,033...84,490,211
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions ISO Probenecid inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione] CTD PMID:11880368 NCBI chr 1:101,954,786...102,013,252
Ensembl chr 1:101,959,540...102,013,243
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein] CTD PMID:24768735 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein] CTD PMID:24768735 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Card10 caspase recruitment domain family, member 10 multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CARD10 mRNA CTD PMID:25406165 NCBI chr 7:119,998,639...120,028,632
Ensembl chr 7:119,999,472...120,027,026
JBrowse link
G Casp1 caspase 1 multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CASP1 mRNA]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CASP1 mRNA CTD PMID:25406165 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein] CTD PMID:24768735 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein] CTD PMID:24768735 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
EXP
ISO
Probenecid inhibits the reaction [Uric Acid results in increased expression of CCL2 protein]
Probenecid analog results in increased expression of CCL2 mRNA
1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CCL2 mRNA]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CCL2 mRNA
CTD PMID:16113518 PMID:24104198 PMID:25406165 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Probenecid promotes the reaction [10-nitro-oleic acid results in decreased expression of CCND1 protein] CTD PMID:29158255 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO Probenecid promotes the reaction [10-nitro-oleic acid results in increased expression of CDKN1A protein] CTD PMID:29158255 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA] CTD PMID:24768735 NCBI chr 2:14,699,878...14,701,903
Ensembl chr 2:14,699,882...14,701,903
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions ISO Probenecid inhibits the reaction [4-cresol sulfate results in increased expression of CYBA mRNA] CTD PMID:23325087 NCBI chr19:55,249,634...55,257,824
Ensembl chr19:55,249,616...55,257,876
JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein] CTD PMID:24768735 NCBI chr 7:117,409,576...117,411,953
Ensembl chr 7:117,409,576...117,411,953
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO Probenecid promotes the reaction [CYP2C8 protein affects the chemical synthesis of carbamazepine epoxide]; Probenecid promotes the reaction [CYP2C8 protein affects the metabolism of Carbamazepine] CTD PMID:15915352 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions
decreases expression
ISO Probenecid promotes the reaction [CYP3A4 protein affects the chemical synthesis of carbamazepine epoxide]; Probenecid promotes the reaction [CYP3A4 protein affects the metabolism of Carbamazepine]
Probenecid results in decreased expression of CYP3A4 mRNA
CTD PMID:15915352 PMID:16837568 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of FADD mRNA CTD PMID:25406165 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Faslg Fas ligand multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of FASL mRNA CTD PMID:25406165 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of GFAP protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GFAP protein] CTD PMID:25064079 NCBI chr10:90,990,762...90,999,435
Ensembl chr10:90,990,762...90,999,506
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO Probenecid inhibits the reaction [cidofovir results in increased secretion of HAVCR1 protein] CTD PMID:29738843 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]; 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA CTD PMID:25406165 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [Probenecid binds to Dextrans] inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein] CTD PMID:30102254 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO Probenecid inhibits the reaction [4-cresol sulfate results in increased expression of NOX4 mRNA] CTD PMID:23325087 NCBI chr 1:150,796,359...150,976,186
Ensembl chr 1:150,797,084...150,976,194
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] affects the localization of and results in decreased expression of NR4A2 protein]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] affects the localization of and results in decreased expression of NR4A2 protein CTD PMID:25406165 NCBI chr 3:43,111,258...43,128,391
Ensembl chr 3:43,111,240...43,119,159
JBrowse link
G Ocln occludin multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of OCLN protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of OCLN protein] CTD PMID:25064079 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Panx1 Pannexin 1 decreases activity
multiple interactions
ISO Probenecid results in decreased activity of PANX1 protein
Probenecid inhibits the reaction [PANX1 protein results in increased export of Adenosine Triphosphate]
CTD PMID:19023039 PMID:19213873 NCBI chr 8:13,567,185...13,606,040
Ensembl chr 8:13,566,739...13,606,040
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Probenecid promotes the reaction [10-nitro-oleic acid results in increased cleavage of PARP1 protein] CTD PMID:29158255 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Ren renin multiple interactions ISO Probenecid inhibits the reaction [Bumetanide results in increased secretion of REN protein] CTD PMID:7040495 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC18A2 protein CTD PMID:19653878 NCBI chr 1:280,397,831...280,457,968
Ensembl chr 1:280,423,079...280,457,148
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein] CTD PMID:22865646 PMID:22967667 NCBI chr 1:48,273,639...48,300,645
Ensembl chr 1:48,273,611...48,300,655
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions
affects activity
ISO Probenecid inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid]
Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Probenecid inhibits the reaction [SLC22A12 protein affects the transport of Uric Acid]
Probenecid affects the activity of SLC22A12 protein
CTD PMID:14694169 PMID:14747372 PMID:21272127 PMID:22865646 PMID:22967667 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein] CTD PMID:22865646 PMID:22967667 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Slc22a20 solute carrier family 22 member 20 multiple interactions ISO Probenecid inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] CTD PMID:16478971 NCBI chr 1:221,327,608...221,344,367
Ensembl chr 1:221,328,711...221,343,889
JBrowse link
G Slc22a25 solute carrier family 22, member 25 multiple interactions
decreases activity
ISO Probenecid inhibits the reaction [SLC22A9 protein results in increased import of estrone sulfate]; Probenecid inhibits the reaction [SLC22A9 protein results in increased uptake of estrone sulfate]
Probenecid results in decreased activity of SLC22A9 protein
CTD PMID:17132213 PMID:28629854 NCBI chr 1:224,596,886...224,698,512
Ensembl chr 1:224,596,887...224,698,514
JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein] CTD PMID:22865646 PMID:22967667 NCBI chr10:39,334,972...39,373,508 JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein] CTD PMID:22865646 PMID:22967667 NCBI chr10:39,201,101...39,228,090
Ensembl chr10:39,201,107...39,323,853
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions
decreases activity
ISO
EXP
Probenecid inhibits the reaction [[SLC22A6 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyadenosin-N(6)-yl)aristolactam I]; Probenecid inhibits the reaction [[SLC22A6 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyguanosin-N(2)-yl)aristolactam I]; Probenecid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A6 protein results in increased import of p-Aminohippuric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-(S)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to adefovir]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to N(6)-cyclopropyl-9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to Tenofovir]; Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]]; Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]
Probenecid results in decreased activity of SLC22A6 protein
Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]
Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of ochratoxin A]
CTD PMID:10336520 PMID:11602689 PMID:12472777 PMID:12606766 PMID:19643159 PMID:21561794 PMID:22865646 PMID:22967667 PMID:23856525 PMID:27989701 PMID:28629854 PMID:28890383 PMID:29045746 PMID:31364238 PMID:31830554 PMID:32003934 PMID:32305507 NCBI chr 1:224,824,809...224,833,284
Ensembl chr 1:224,824,799...224,833,259
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
decreases activity
decreases expression
ISO
EXP
Probenecid inhibits the reaction [[SLC22A8 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyadenosin-N(6)-yl)aristolactam I]; Probenecid inhibits the reaction [[SLC22A8 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyguanosin-N(2)-yl)aristolactam I]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Cimetidine]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]
Probenecid results in decreased activity of SLC22A8 protein
Probenecid results in decreased expression of SLC22A8 mRNA; Probenecid results in decreased expression of SLC22A8 protein
Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Cimetidine]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]; Probenecid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Ranitidine]
CTD PMID:10224140 PMID:11306713 PMID:15319347 PMID:16006492 PMID:19643159 PMID:23129053 PMID:27989701 PMID:28629854 PMID:28890383 PMID:29045746 PMID:31364238 PMID:31830554 PMID:32003934 PMID:32305507 NCBI chr 1:224,799,444...224,818,482
Ensembl chr 1:224,800,252...224,818,482
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SLC2A1 protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SLC2A1 protein] CTD PMID:25064079 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a9 solute carrier family 2 member 9 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein] CTD PMID:22967667 NCBI chr14:77,067,537...77,192,702
Ensembl chr14:77,067,503...77,192,702
JBrowse link
G Slc5a6 solute carrier family 5 member 6 multiple interactions ISO Probenecid inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 6:26,685,823...26,697,110
Ensembl chr 6:26,686,033...26,697,116
JBrowse link
G Slc5a8 solute carrier family 5 member 8 decreases activity ISO Probenecid results in decreased activity of SLC5A8 protein CTD PMID:15090606 NCBI chr 7:29,434,175...29,476,807
Ensembl chr 7:29,435,444...29,477,947
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC6A3 protein]; 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC6A3 protein]; 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC6A3 protein]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC6A3 protein; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SLC6A3 protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SLC6A3 protein] CTD PMID:19653878 PMID:25064079 PMID:25406165 NCBI chr 1:32,323,011...32,363,983
Ensembl chr 1:32,321,580...32,363,983
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO Probenecid inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein] CTD PMID:27989701 NCBI chr 4:175,814,118...175,881,775
Ensembl chr 4:175,814,118...175,881,768
JBrowse link
G Tas2r118 taste receptor, type 2, member 118 multiple interactions ISO Probenecid binds to and results in decreased activity of TAS2R16 protein; Probenecid inhibits the reaction [salicin results in increased activity of TAS2R16 protein] CTD PMID:21629661 NCBI chr 4:51,002,218...51,003,117
Ensembl chr 4:51,002,218...51,003,117
JBrowse link
G Tas2r138 taste receptor, type 2, member 138 multiple interactions
decreases activity
ISO Probenecid inhibits the reaction [Phenylthiourea results in increased activity of TAS2R38 protein]; Probenecid inhibits the reaction [Propylthiouracil results in increased activity of TAS2R38 protein]
Probenecid results in decreased activity of TAS2R38 protein
CTD PMID:21629661 NCBI chr 4:68,831,221...68,832,216
Ensembl chr 4:68,831,221...68,832,216
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Probenecid inhibits the reaction [4-cresol sulfate results in increased expression of and results in increased secretion of TGFB1 protein] CTD PMID:23325087 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein]; 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein]; 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein CTD PMID:19653878 PMID:25406165 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of TJP1 protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of TJP1 protein] CTD PMID:25064079 NCBI chr 1:126,146,489...126,515,359
Ensembl chr 1:126,146,489...126,227,469
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA CTD PMID:25406165 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TNF mRNA CTD PMID:25406165 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 affects response to substance ISO UGT1A3 affects the susceptibility to Probenecid CTD PMID:17880178 NCBI chr 9:95,285,592...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects response to substance ISO UGT1A9 affects the susceptibility to Probenecid CTD PMID:17880178 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 affects response to substance ISO UGT2B7 affects the susceptibility to Probenecid CTD PMID:17880178 NCBI chr14:22,597,103...22,619,968 JBrowse link
G Umod uromodulin multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in increased expression of and results in decreased secretion of UMOD protein] CTD PMID:22865646 NCBI chr 1:189,186,027...189,199,939
Ensembl chr 1:189,186,026...189,199,376
JBrowse link
sulfinpyrazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Sulfinpyrazone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Sulfinpyrazone results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
ISO
EXP
Sulfinpyrazone results in decreased activity of ABCC1 protein
[Sulfinpyrazone results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine
CTD PMID:12893836 PMID:15044619 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity ISO Sulfinpyrazone results in decreased activity of ABCC2 protein CTD PMID:14569069 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Sulfinpyrazone results in increased expression of CYP2B6 protein CTD PMID:14977870 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Sulfinpyrazone results in decreased activity of CYP2C8 protein CTD PMID:12464242 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression
increases activity
ISO Sulfinpyrazone results in increased expression of CYP3A4 mRNA
Sulfinpyrazone results in increased activity of CYP3A4 protein
CTD PMID:9512926 PMID:10219967 PMID:12065438 PMID:16837568 PMID:17954527 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine] CTD PMID:15044619 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Sulfinpyrazone inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide] CTD PMID:15999103 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO Sulfinpyrazone binds to and results in increased activity of NR1I2 protein
Sulfinpyrazone results in increased activity of NR1I2 protein
CTD PMID:12065438 PMID:14977870 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Sulfinpyrazone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid] CTD PMID:21272127 NCBI chr 1:221,910,787...221,919,277
Ensembl chr 1:221,910,767...221,919,301
JBrowse link

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              uricosuric drug + 394
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