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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:renal agent
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Accession:CHEBI:35846 term browser browse the term
Definition:A drug used for its effect on the kidneys' regulation of body fluid composition and volume.
Synonyms:related_synonym: renal agents



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apazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Apazone results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
benzbromarone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Benzbromarone results in decreased activity of ABCB11 protein
Benzbromarone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:20829430 PMID:23956101 PMID:24014644 PMID:28437613 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A affects expression EXP Benzbromarone affects the expression of ABCB1A mRNA CTD PMID:19483382 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Benzbromarone results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
affects activity
ISO Benzbromarone inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]; Benzbromarone inhibits the reaction [ABCC1 protein results in increased secretion of Daunorubicin]
Benzbromarone affects the activity of ABCC1 protein
CTD PMID:9096673 PMID:9334814 PMID:15041471 PMID:16101123 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
decreases activity
EXP
ISO
[Benzbromarone results in decreased activity of ABCC2 protein] inhibits the reaction [Glucose results in increased secretion of S-(2,4-dinitrophenyl)glutathione]; [Benzbromarone results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium
Benzbromarone inhibits the reaction [ABCC2 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein]
CTD PMID:19782883 PMID:19853032 PMID:22646477 PMID:31348918 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Benzbromarone inhibits the reaction [ABCC3 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:31348918 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO Benzbromarone inhibits the reaction [ABCC5 protein results in increased transport of 5(6)-carboxy-2',7'-dichlorofluorescein] CTD PMID:31348918 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions
decreases activity
affects expression
ISO
EXP
Benzbromarone inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione]
Benzbromarone results in decreased activity of ABCC6 protein
Benzbromarone affects the expression of ABCC6 mRNA
CTD PMID:11880368 PMID:14667841 PMID:19483382 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 affects expression EXP Benzbromarone affects the expression of ABCG5 mRNA CTD PMID:19483382 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Abhd1 abhydrolase domain containing 1 affects expression EXP Benzbromarone affects the expression of ABHD1 mRNA CTD PMID:19483382 NCBI chr 6:25,422,526...25,427,514
Ensembl chr 6:25,422,526...25,427,514
JBrowse link
G Abhd14b abhydrolase domain containing 14b affects expression EXP Benzbromarone affects the expression of ABHD14B mRNA CTD PMID:19483382 NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119
JBrowse link
G Abhd17a abhydrolase domain containing 17A, depalmitoylase affects expression EXP Benzbromarone affects the expression of ABHD17A mRNA CTD PMID:19483382 NCBI chr 7:9,124,332...9,132,762
Ensembl chr 7:9,124,332...9,130,762
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression EXP Benzbromarone affects the expression of ACACA mRNA CTD PMID:19483382 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain affects expression EXP Benzbromarone affects the expression of ACADL mRNA CTD PMID:19483382 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression ISO Benzbromarone results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Aco1 aconitase 1 affects expression EXP Benzbromarone affects the expression of ACO1 mRNA CTD PMID:19483382 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391
JBrowse link
G Aco2 aconitase 2 affects expression EXP Benzbromarone affects the expression of ACO2 mRNA CTD PMID:19483382 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261
JBrowse link
G Acot12 acyl-CoA thioesterase 12 affects expression EXP Benzbromarone affects the expression of ACOT12 mRNA CTD PMID:19483382 NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
JBrowse link
G Acot4 acyl-CoA thioesterase 4 affects expression EXP Benzbromarone affects the expression of ACOT4 mRNA CTD PMID:19483382 NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
JBrowse link
G Adam15 ADAM metallopeptidase domain 15 affects expression EXP Benzbromarone affects the expression of ADAM15 mRNA CTD PMID:19483382 NCBI chr 2:174,754,631...174,765,136
Ensembl chr 2:174,754,633...174,765,113
JBrowse link
G Add1 adducin 1 affects expression EXP Benzbromarone affects the expression of ADD1 mRNA CTD PMID:19483382 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Adh4 alcohol dehydrogenase 4 (class II), pi polypeptide affects expression EXP Benzbromarone affects the expression of ADH4 mRNA CTD PMID:19483382 NCBI chr 2:226,948,717...226,966,747
Ensembl chr 2:226,947,466...226,987,591
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression
ISO 2-chloro-5-nitrobenzanilide inhibits the reaction [Benzbromarone results in increased expression of ADIPOQ mRNA]
Benzbromarone results in increased expression of ADIPOQ protein
CTD PMID:19048458 PMID:21329621 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Adtrp androgen-dependent TFPI-regulating protein affects expression EXP Benzbromarone affects the expression of ADTRP mRNA CTD PMID:19483382 NCBI chr17:22,930,012...22,993,834
Ensembl chr17:22,930,740...22,993,826
JBrowse link
G Afm afamin affects expression EXP Benzbromarone affects the expression of AFM mRNA CTD PMID:19483382 NCBI chr14:17,531,026...17,563,868
Ensembl chr14:17,531,024...17,563,870
JBrowse link
G Agt angiotensinogen affects expression EXP Benzbromarone affects the expression of AGT mRNA CTD PMID:19483382 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Agtr1a angiotensin II receptor, type 1a affects expression EXP Benzbromarone affects the expression of AGTR1A mRNA CTD PMID:19483382 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Akr1a1 aldo-keto reductase family 1 member A1 affects expression EXP Benzbromarone affects the expression of AKR1A1 mRNA CTD PMID:19483382 NCBI chr 5:130,092,945...130,130,277
Ensembl chr 5:130,092,732...130,113,674
JBrowse link
G Akr1b8 aldo-keto reductase family 1, member B8 decreases activity EXP Benzbromarone results in decreased activity of AKR1B8 protein CTD PMID:18845131 NCBI chr 4:62,997,241...63,009,815
Ensembl chr 4:62,997,161...63,010,097
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 multiple interactions ISO Benzbromarone binds to and results in decreased activity of AKR1C1 protein CTD PMID:12604236 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 decreases activity ISO Benzbromarone results in decreased activity of AKR1C2 protein CTD PMID:12604236 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases activity ISO Benzbromarone results in decreased activity of AKR1C3 protein CTD PMID:12604236 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Akr7a2 aldo-keto reductase family 7, member A2 affects expression EXP Benzbromarone affects the expression of AKR7A2 mRNA CTD PMID:19483382 NCBI chr 5:151,552,375...151,560,914
Ensembl chr 5:151,552,343...151,560,909
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 affects expression EXP Benzbromarone affects the expression of AKR7A3 mRNA CTD PMID:19483382 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 affects expression EXP Benzbromarone affects the expression of ALDH1A1 mRNA CTD PMID:19483382 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member affects expression EXP Benzbromarone affects the expression of ALDH2 mRNA CTD PMID:19483382 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Alkbh7 alkB homolog 7 affects expression EXP Benzbromarone affects the expression of ALKBH7 mRNA CTD PMID:19483382 NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044
JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 affects expression EXP Benzbromarone affects the expression of AP2M1 mRNA CTD PMID:19483382 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140
JBrowse link
G Apcs amyloid P component, serum affects expression EXP Benzbromarone affects the expression of APCS mRNA CTD PMID:19483382 NCBI chr13:85,373,338...85,374,134
Ensembl chr13:85,373,220...85,374,298
JBrowse link
G Apoa4 apolipoprotein A4 affects expression EXP Benzbromarone affects the expression of APOA4 mRNA CTD PMID:19483382 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
JBrowse link
G Apoh apolipoprotein H affects expression EXP Benzbromarone affects the expression of APOH mRNA CTD PMID:19483382 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329
JBrowse link
G Apool apolipoprotein O-like affects expression EXP Benzbromarone affects the expression of APOOL mRNA CTD PMID:19483382 NCBI chr  X:77,377,685...77,443,670
Ensembl chr  X:77,377,781...77,443,900
JBrowse link
G Arg1 arginase 1 affects expression EXP Benzbromarone affects the expression of ARG1 mRNA CTD PMID:19483382 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Arl6ip1 ADP-ribosylation factor like GTPase 6 interacting protein 1 affects expression EXP Benzbromarone affects the expression of ARL6IP1 mRNA CTD PMID:19483382 NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994
JBrowse link
G Asgr2 asialoglycoprotein receptor 2 affects expression EXP Benzbromarone affects the expression of ASGR2 mRNA CTD PMID:19483382 NCBI chr10:54,821,407...54,834,624
Ensembl chr10:54,821,438...54,834,617
JBrowse link
G Atf5 activating transcription factor 5 affects expression EXP Benzbromarone affects the expression of ATF5 mRNA CTD PMID:19483382 NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707
JBrowse link
G Atp5f1e ATP synthase F1 subunit epsilon affects expression EXP Benzbromarone affects the expression of ATP5F1E mRNA CTD PMID:19483382 NCBI chr 3:163,259,072...163,261,974
Ensembl chr 3:163,260,476...163,261,450
JBrowse link
G Atp6ap2 ATPase H+ transporting accessory protein 2 affects expression EXP Benzbromarone affects the expression of ATP6AP2 mRNA CTD PMID:19483382 NCBI chr  X:10,183,983...10,210,948
Ensembl chr  X:10,183,068...10,210,918
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression EXP Benzbromarone affects the expression of ATP6V1A mRNA CTD PMID:19483382 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atp6v1f ATPase H+ transporting V1 subunit F affects expression EXP Benzbromarone affects the expression of ATP6V1F mRNA CTD PMID:19483382 NCBI chr 4:58,067,666...58,070,628 JBrowse link
G Baat bile acid CoA:amino acid N-acyltransferase affects expression EXP Benzbromarone affects the expression of BAAT mRNA CTD PMID:19483382 NCBI chr 5:63,851,668...63,860,641
Ensembl chr 5:63,850,705...63,860,685
JBrowse link
G Bcl6b BCL6B, transcription repressor affects expression EXP Benzbromarone affects the expression of BCL6B mRNA CTD PMID:19483382 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Bmf Bcl2 modifying factor affects expression EXP Benzbromarone affects the expression of BMF mRNA CTD PMID:19483382 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145
JBrowse link
G Bnip3 BCL2 interacting protein 3 affects expression EXP Benzbromarone affects the expression of BNIP3 mRNA CTD PMID:19483382 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
JBrowse link
G Btf3 basic transcription factor 3 affects expression EXP Benzbromarone affects the expression of BTF3 mRNA CTD PMID:19483382 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G C1qbp complement C1q binding protein affects expression EXP Benzbromarone affects the expression of C1QBP mRNA CTD PMID:19483382 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
JBrowse link
G C1s complement C1s affects expression EXP Benzbromarone affects the expression of C1S mRNA CTD PMID:19483382 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G C2cd2 C2 calcium-dependent domain containing 2 affects expression EXP Benzbromarone affects the expression of C2CD2 mRNA CTD PMID:19483382 NCBI chr11:37,225,321...37,289,741
Ensembl chr11:37,227,415...37,289,739
JBrowse link
G C4bpa complement component 4 binding protein, alpha affects expression EXP Benzbromarone affects the expression of C4BPA mRNA CTD PMID:19483382 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205
JBrowse link
G C7 complement C7 affects expression EXP Benzbromarone affects the expression of C7 mRNA CTD PMID:19483382 NCBI chr 2:54,088,116...54,165,102
Ensembl chr 2:54,088,116...54,158,535
JBrowse link
G C8b complement C8 beta chain affects expression EXP Benzbromarone affects the expression of C8B mRNA CTD PMID:19483382 NCBI chr 5:119,535,009...119,572,565
Ensembl chr 5:119,535,146...119,572,565
JBrowse link
G Ca3 carbonic anhydrase 3 affects expression EXP Benzbromarone affects the expression of CAR3 mRNA CTD PMID:19483382 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280
JBrowse link
G Cadps2 calcium dependent secretion activator 2 affects expression EXP Benzbromarone affects the expression of CADPS2 mRNA CTD PMID:19483382 NCBI chr 4:51,780,415...52,309,641
Ensembl chr 4:51,781,053...52,309,829
JBrowse link
G Caprin1 cell cycle associated protein 1 affects expression EXP Benzbromarone affects the expression of CAPRIN1 mRNA CTD PMID:19483382 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Car2 carbonic anhydrase 2 affects expression EXP Benzbromarone affects the expression of CA2 mRNA CTD PMID:19483382 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Casp3 caspase 3 affects expression EXP Benzbromarone affects the expression of CASP3 mRNA CTD PMID:19483382 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase increases activity EXP Benzbromarone results in increased activity of CAT protein CTD PMID:2260096 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cd36 CD36 molecule increases expression ISO Benzbromarone results in increased expression of CD36 mRNA CTD PMID:19048458 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cdo1 cysteine dioxygenase type 1 affects expression EXP Benzbromarone affects the expression of CDO1 mRNA CTD PMID:19483382 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296
JBrowse link
G Cept1 choline/ethanolamine phosphotransferase 1 affects expression EXP Benzbromarone affects the expression of CEPT1 mRNA CTD PMID:19483382 NCBI chr 2:193,994,220...194,036,141
Ensembl chr 2:193,993,447...194,035,578
JBrowse link
G Ces2h carboxylesterase 2H affects expression EXP Benzbromarone affects the expression of CES2 mRNA CTD PMID:19483382 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830
JBrowse link
G Cfi complement factor I affects expression EXP Benzbromarone affects the expression of CFI mRNA CTD PMID:19483382 NCBI chr 2:218,389,079...218,430,565
Ensembl chr 2:218,387,990...218,430,561
JBrowse link
G Chp1 calcineurin-like EF-hand protein 1 affects expression EXP Benzbromarone affects the expression of CHP1 mRNA CTD PMID:19483382 NCBI chr 3:106,536,009...106,571,255
Ensembl chr 3:106,536,004...106,571,251
JBrowse link
G Cisd1 CDGSH iron sulfur domain 1 affects expression EXP Benzbromarone affects the expression of CISD1 mRNA CTD PMID:19483382 NCBI chr20:17,255,302...17,268,688
Ensembl chr20:17,255,151...17,284,924
JBrowse link
G Clcn4 chloride voltage-gated channel 4 affects expression EXP Benzbromarone affects the expression of CLCN4 mRNA CTD PMID:19483382 NCBI chr  X:23,729,194...23,795,391
Ensembl chr  X:23,729,338...23,793,238
JBrowse link
G Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit affects expression EXP Benzbromarone affects the expression of CLPP mRNA CTD PMID:19483382 NCBI chr 9:1,831,680...1,837,700
Ensembl chr 9:1,830,311...1,837,693
JBrowse link
G Clptm1l CLPTM1-like affects expression EXP Benzbromarone affects the expression of CLPTM1L mRNA CTD PMID:19483382 NCBI chr 1:29,667,545...29,683,530
Ensembl chr 1:29,667,545...29,683,530
JBrowse link
G Cmbl carboxymethylenebutenolidase homolog affects expression EXP Benzbromarone affects the expression of CMBL mRNA CTD PMID:19483382 NCBI chr 2:82,569,257...82,591,007
Ensembl chr 2:82,571,888...82,591,009
JBrowse link
G Cmpk1 cytidine/uridine monophosphate kinase 1 affects expression EXP Benzbromarone affects the expression of CMPK1 mRNA CTD PMID:19483382 NCBI chr 5:128,480,301...128,507,830
Ensembl chr 5:128,480,301...128,507,830
JBrowse link
G Copg1 COPI coat complex subunit gamma 1 affects expression EXP Benzbromarone affects the expression of COPG1 mRNA CTD PMID:19483382 NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616
JBrowse link
G Cops4 COP9 signalosome subunit 4 affects expression EXP Benzbromarone affects the expression of COPS4 mRNA CTD PMID:19483382 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887
JBrowse link
G Coq3 coenzyme Q3 methyltransferase affects expression EXP Benzbromarone affects the expression of COQ3 mRNA CTD PMID:19483382 NCBI chr 5:35,429,567...35,460,613
Ensembl chr 5:35,429,574...35,460,607
JBrowse link
G Cox4i1 cytochrome c oxidase subunit 4i1 affects expression EXP Benzbromarone affects the expression of COX4I1 mRNA CTD PMID:19483382 NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921
JBrowse link
G Cpn1 carboxypeptidase N subunit 1 affects expression EXP Benzbromarone affects the expression of CPN1 mRNA CTD PMID:19483382 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465
JBrowse link
G Cpq carboxypeptidase Q affects expression EXP Benzbromarone affects the expression of CPQ mRNA CTD PMID:19483382 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A increases expression ISO Benzbromarone results in increased expression of CPT1A mRNA; Benzbromarone results in increased expression of CPT1A protein CTD PMID:25108121 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
JBrowse link
G Crem cAMP responsive element modulator affects expression EXP Benzbromarone affects the expression of CREM mRNA CTD PMID:19483382 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989
JBrowse link
G Crp C-reactive protein multiple interactions
decreases expression
ISO Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein]
Benzbromarone results in decreased expression of CRP protein
CTD PMID:21329621 NCBI chr13:85,131,635...85,175,179
Ensembl chr13:85,124,977...85,175,178
JBrowse link
G Csnk2b casein kinase 2 beta affects expression EXP Benzbromarone affects the expression of CSNK2B mRNA CTD PMID:19483382 NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression EXP Benzbromarone affects the expression of CSRP1 mRNA CTD PMID:19483382 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Ctnna1 catenin alpha 1 affects expression EXP Benzbromarone affects the expression of CTNNA1 mRNA CTD PMID:19483382 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Benzbromarone results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Benzbromarone results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 affects expression EXP Benzbromarone affects the expression of CYP2A1 mRNA CTD PMID:19483382 NCBI chr 1:82,231,611...82,244,887
Ensembl chr 1:82,231,611...82,244,887
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects expression EXP Benzbromarone affects the expression of CYP2B2 mRNA CTD PMID:19483382 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 affects expression EXP Benzbromarone affects the expression of CYP2B3 mRNA CTD PMID:19483382 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 multiple interactions ISO Benzbromarone analog binds to and results in decreased activity of CYP2C19 protein; Benzbromarone binds to and results in decreased activity of CYP2C19 protein CTD PMID:15615526 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596
JBrowse link
G Cyp2d3 cytochrome P450, family 2, subfamily d, polypeptide 3 affects expression EXP Benzbromarone affects the expression of CYP2D3 mRNA CTD PMID:19483382 NCBI chr 7:113,917,711...113,922,068
Ensembl chr 7:113,908,947...113,922,084
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects expression EXP Benzbromarone affects the expression of CYP2D4 mRNA CTD PMID:19483382 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 affects expression EXP Benzbromarone affects the expression of CYP2F4 mRNA CTD PMID:19483382 NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 affects expression EXP Benzbromarone affects the expression of CYP2J4 mRNA CTD PMID:19483382 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794
JBrowse link
G Cyp2t1 cytochrome P450, family 2, subfamily t, polypeptide 1 affects expression EXP Benzbromarone affects the expression of CYP2T1 mRNA CTD PMID:19483382 NCBI chr 1:82,446,321...82,451,564
Ensembl chr 1:82,446,921...82,451,563
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects expression EXP Benzbromarone affects the expression of CYP3A23-3A1 mRNA CTD PMID:19483382 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects expression EXP Benzbromarone affects the expression of CYP3A9 mRNA CTD PMID:19483382 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
JBrowse link
G Cyp4a8 cytochrome P450, family 4, subfamily a, polypeptide 8 affects expression EXP Benzbromarone affects the expression of CYP4A8 mRNA CTD PMID:19483382 NCBI chr 5:128,702,130...128,733,476
Ensembl chr 5:128,702,131...128,733,476
JBrowse link
G Cyp4f6 cytochrome P450, family 4, subfamily f, polypeptide 6 affects expression EXP Benzbromarone affects the expression of CYP4F6 mRNA CTD PMID:19483382 NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein affects expression EXP Benzbromarone affects the expression of DBI mRNA CTD PMID:19483382 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Dcaf11 DDB1 and CUL4 associated factor 11 affects expression EXP Benzbromarone affects the expression of DCAF11 mRNA CTD PMID:19483382 NCBI chr15:29,046,744...29,057,450
Ensembl chr15:29,046,826...29,057,669
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase affects expression EXP Benzbromarone affects the expression of DCXR mRNA CTD PMID:19483382 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Decr1 2,4-dienoyl-CoA reductase 1 affects expression EXP Benzbromarone affects the expression of DECR1 mRNA CTD PMID:19483382 NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
JBrowse link
G Dexi Dexi homolog affects expression EXP Benzbromarone affects the expression of DEXI mRNA CTD PMID:19483382 NCBI chr10:5,126,021...5,138,746
Ensembl chr10:5,137,288...5,138,738
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 affects expression EXP Benzbromarone affects the expression of DGAT1 mRNA CTD PMID:19483382 NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase affects expression EXP Benzbromarone affects the expression of DHCR24 mRNA CTD PMID:19483382 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dhrs4 dehydrogenase/reductase 4 affects expression EXP Benzbromarone affects the expression of DHRS4 mRNA CTD PMID:19483382 NCBI chr15:28,966,544...28,978,135
Ensembl chr15:28,966,553...28,978,127
JBrowse link
G Dhrs7b dehydrogenase/reductase 7B affects expression EXP Benzbromarone affects the expression of DHRS7B mRNA CTD PMID:19483382 NCBI chr10:45,504,344...45,537,094
Ensembl chr10:45,504,426...45,537,076
JBrowse link
G Dhx16 DEAH-box helicase 16 affects expression EXP Benzbromarone affects the expression of DHX16 mRNA CTD PMID:19483382 NCBI chr20:2,862,000...2,874,991
Ensembl chr20:2,862,000...2,874,948
JBrowse link
G Dmac2l distal membrane arm assembly component 2 like affects expression EXP Benzbromarone affects the expression of DMAC2L mRNA CTD PMID:19483382 NCBI chr 6:88,205,580...88,223,934
Ensembl chr 6:88,205,700...88,223,933
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 affects expression EXP Benzbromarone affects the expression of DNAJC3 mRNA CTD PMID:19483382 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dpp4 dipeptidylpeptidase 4 affects expression EXP Benzbromarone affects the expression of DPP4 mRNA CTD PMID:19483382 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dpyd dihydropyrimidine dehydrogenase affects expression EXP Benzbromarone affects the expression of DPYD mRNA CTD PMID:19483382 NCBI chr 2:206,609,043...207,474,982
Ensembl chr 2:206,609,122...207,474,982
JBrowse link
G Ears2 glutamyl-tRNA synthetase 2, mitochondrial affects expression EXP Benzbromarone affects the expression of EARS2 mRNA CTD PMID:19483382 NCBI chr 1:176,597,986...176,625,848
Ensembl chr 1:176,597,986...176,625,836
JBrowse link
G Echs1 enoyl-CoA hydratase, short chain 1 affects expression EXP Benzbromarone affects the expression of ECHS1 mRNA CTD PMID:19483382 NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression EXP Benzbromarone affects the expression of ECI1 mRNA CTD PMID:19483382 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Eci2 enoyl-CoA delta isomerase 2 affects expression EXP Benzbromarone affects the expression of ECI2 mRNA CTD PMID:19483382 NCBI chr17:29,850,884...29,886,781
Ensembl chr17:29,870,391...29,886,781
JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma affects expression EXP Benzbromarone affects the expression of EEF1G mRNA CTD PMID:19483382 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382
JBrowse link
G Ehhadh enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase affects expression EXP Benzbromarone affects the expression of EHHADH mRNA CTD PMID:19483382 NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 affects expression EXP Benzbromarone affects the expression of EIF4A2 mRNA CTD PMID:19483382 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 affects expression EXP Benzbromarone affects the expression of EIF4EBP1 mRNA CTD PMID:19483382 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
JBrowse link
G Eif4h eukaryotic translation initiation factor 4H affects expression EXP Benzbromarone affects the expression of EIF4H mRNA CTD PMID:19483382 NCBI chr12:22,083,155...22,099,876
Ensembl chr12:22,082,835...22,099,876
JBrowse link
G Enc1 ectodermal-neural cortex 1 affects expression EXP Benzbromarone affects the expression of ENC1 mRNA CTD PMID:19483382 NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
JBrowse link
G Eno1 enolase 1 affects expression EXP Benzbromarone affects the expression of ENO1 mRNA CTD PMID:19483382 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336
JBrowse link
G Enpep glutamyl aminopeptidase affects expression EXP Benzbromarone affects the expression of ENPEP mRNA CTD PMID:19483382 NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947
JBrowse link
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 affects expression EXP Benzbromarone affects the expression of ENPP1 mRNA CTD PMID:19483382 NCBI chr 1:20,698,746...20,763,741
Ensembl chr 1:20,698,764...20,763,715
JBrowse link
G Epcam epithelial cell adhesion molecule affects expression EXP Benzbromarone affects the expression of EPCAM mRNA CTD PMID:19483382 NCBI chr 6:6,880,142...6,896,103
Ensembl chr 6:6,878,237...6,896,127
JBrowse link
G Erp29 endoplasmic reticulum protein 29 affects expression EXP Benzbromarone affects the expression of ERP29 mRNA CTD PMID:19483382 NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376
JBrowse link
G Esd esterase D affects expression EXP Benzbromarone affects the expression of ESD mRNA CTD PMID:19483382 NCBI chr15:50,043,634...50,063,134
Ensembl chr15:50,043,632...50,063,144
JBrowse link
G Etfb electron transfer flavoprotein subunit beta affects expression EXP Benzbromarone affects the expression of ETFB mRNA CTD PMID:19483382 NCBI chr 1:93,851,908...93,866,072
Ensembl chr 1:93,851,858...93,866,068
JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 decreases activity ISO Benzbromarone results in decreased activity of EYA2 protein CTD PMID:22545090 NCBI chr 3:154,335,558...154,519,006
Ensembl chr 3:154,335,400...154,518,793
JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 decreases activity ISO Benzbromarone results in decreased activity of EYA3 protein CTD PMID:22545090 NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518
JBrowse link
G Faah fatty acid amide hydrolase affects expression EXP Benzbromarone affects the expression of FAAH mRNA CTD PMID:19483382 NCBI chr 5:129,479,774...129,499,018
Ensembl chr 5:129,479,824...129,498,677
JBrowse link
G Fabp4 fatty acid binding protein 4 increases expression ISO Benzbromarone results in increased expression of FABP4 mRNA CTD PMID:19048458 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Fads2 fatty acid desaturase 2 affects expression EXP Benzbromarone affects the expression of FADS2 mRNA CTD PMID:19483382 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Fbp1 fructose-bisphosphatase 1 affects expression EXP Benzbromarone affects the expression of FBP1 mRNA CTD PMID:19483382 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 affects expression EXP Benzbromarone affects the expression of FDFT1 mRNA CTD PMID:19483382 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase affects expression EXP Benzbromarone affects the expression of FDPS mRNA CTD PMID:19483382 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fdx2 ferredoxin 2 affects expression EXP Benzbromarone affects the expression of FDX2 mRNA CTD PMID:19483382 NCBI chr 8:19,604,916...19,609,832
Ensembl chr 8:19,604,916...19,609,849
JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 affects expression EXP Benzbromarone affects the expression of FMO1 mRNA CTD PMID:19483382 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647
JBrowse link
G Gamt guanidinoacetate N-methyltransferase affects expression EXP Benzbromarone affects the expression of GAMT mRNA CTD PMID:19483382 NCBI chr 7:9,448,590...9,451,778
Ensembl chr 7:9,448,628...9,451,778
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase affects expression EXP Benzbromarone affects the expression of GAPDH mRNA CTD PMID:19483382 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gbe1 1,4-alpha-glucan branching enzyme 1 affects expression EXP Benzbromarone affects the expression of GBE1 mRNA CTD PMID:19483382 NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210
JBrowse link
G Gchfr GTP cyclohydrolase I feedback regulator affects expression EXP Benzbromarone affects the expression of GCHFR mRNA CTD PMID:19483382 NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080
JBrowse link
G Ggh gamma-glutamyl hydrolase affects expression EXP Benzbromarone affects the expression of GGH mRNA CTD PMID:19483382 NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
JBrowse link
G Gjb1 gap junction protein, beta 1 affects expression EXP Benzbromarone affects the expression of GJB1 mRNA CTD PMID:19483382 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gpld1 glycosylphosphatidylinositol specific phospholipase D1 affects expression EXP Benzbromarone affects the expression of GPLD1 mRNA CTD PMID:19483382 NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Benzbromarone affects the expression of GPX1 mRNA CTD PMID:19483382 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx4 glutathione peroxidase 4 affects expression EXP Benzbromarone affects the expression of GPX4 mRNA CTD PMID:19483382 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 affects expression EXP Benzbromarone affects the expression of GRINA mRNA CTD PMID:19483382 NCBI chr 7:107,962,194...107,965,368
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grpel1 GrpE-like 1, mitochondrial affects expression EXP Benzbromarone affects the expression of GRPEL1 mRNA CTD PMID:19483382 NCBI chr14:74,292,023...74,298,243
Ensembl chr14:74,292,023...74,298,200
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects expression EXP Benzbromarone affects the expression of GSTT1 mRNA CTD PMID:19483382 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Gtf2h5 general transcription factor IIH subunit 5 affects expression EXP Benzbromarone affects the expression of GTF2H5 mRNA CTD PMID:19483382 NCBI chr 1:46,656,804...46,663,512
Ensembl chr 1:46,656,859...46,664,939
JBrowse link
G Gzma granzyme A affects expression EXP Benzbromarone affects the expression of GZMA mRNA CTD PMID:19483382 NCBI chr 2:44,740,638...44,752,471
Ensembl chr 2:44,740,569...44,752,493
JBrowse link
G H3f3b H3.3 histone B affects expression EXP Benzbromarone affects the expression of H3F3B mRNA CTD PMID:19483382 NCBI chr10:101,256,488...101,258,712
Ensembl chr10:101,256,480...101,258,709
JBrowse link
G Hal histidine ammonia lyase affects expression EXP Benzbromarone affects the expression of HAL mRNA CTD PMID:19483382 NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
JBrowse link
G Hao2 hydroxyacid oxidase 2 affects expression EXP Benzbromarone affects the expression of HAO2 mRNA CTD PMID:19483382 NCBI chr 2:186,200,137...186,232,997
Ensembl chr 2:186,200,504...186,224,425
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 affects expression EXP Benzbromarone affects the expression of HBA-A2 mRNA CTD PMID:19483382 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Benzbromarone affects the expression of HBB mRNA CTD PMID:19483382 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
JBrowse link
G Hdc histidine decarboxylase affects expression EXP Benzbromarone affects the expression of HDC mRNA CTD PMID:19483382 NCBI chr 3:113,847,256...113,865,334
Ensembl chr 3:113,847,260...113,865,341
JBrowse link
G Hgd homogentisate 1, 2-dioxygenase affects expression EXP Benzbromarone affects the expression of HGD mRNA CTD PMID:19483382 NCBI chr11:63,086,750...63,138,325
Ensembl chr11:63,086,752...63,138,323
JBrowse link
G Hmgn1 high mobility group nucleosome binding domain 1 affects expression EXP Benzbromarone affects the expression of HMGN1 mRNA CTD PMID:19483382 NCBI chr11:35,422,328...35,428,247
Ensembl chr11:35,422,328...35,428,254
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 affects expression EXP Benzbromarone affects the expression of HPRT1 mRNA CTD PMID:19483382 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Hps5 HPS5, biogenesis of lysosomal organelles complex 2 subunit 2 affects expression EXP Benzbromarone affects the expression of HPS5 mRNA CTD PMID:19483382 NCBI chr 1:97,281,626...97,320,945
Ensembl chr 1:97,247,598...97,321,019
JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 affects expression EXP Benzbromarone affects the expression of HSD17B4 mRNA CTD PMID:19483382 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952
JBrowse link
G Hsdl2 hydroxysteroid dehydrogenase like 2 affects expression EXP Benzbromarone affects the expression of HSDL2 mRNA CTD PMID:19483382 NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
JBrowse link
G Htra1 HtrA serine peptidase 1 affects expression EXP Benzbromarone affects the expression of HTRA1 mRNA CTD PMID:19483382 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression EXP Benzbromarone affects the expression of IGF1 mRNA CTD PMID:19483382 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igfals insulin-like growth factor binding protein, acid labile subunit affects expression EXP Benzbromarone affects the expression of IGFALS mRNA CTD PMID:19483382 NCBI chr10:13,897,468...13,903,920
Ensembl chr10:13,898,395...13,902,677
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression EXP Benzbromarone affects the expression of IGFBP2 mRNA CTD PMID:19483382 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone CTD PMID:19362101 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Benzbromarone inhibits the reaction [IL1B protein results in increased expression of CRP protein] CTD PMID:21329621 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone CTD PMID:19362101 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Impa1 inositol monophosphatase 1 affects expression EXP Benzbromarone affects the expression of IMPA1 mRNA CTD PMID:19483382 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Inhbe inhibin subunit beta E affects expression EXP Benzbromarone affects the expression of INHBE mRNA CTD PMID:19483382 NCBI chr 7:63,177,558...63,178,983
Ensembl chr 7:63,176,219...63,179,172
JBrowse link
G Isyna1 inositol-3-phosphate synthase 1 affects expression EXP Benzbromarone affects the expression of ISYNA1 mRNA CTD PMID:19483382 NCBI chr16:18,839,143...18,841,979
Ensembl chr16:18,839,145...18,841,979
JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects expression EXP Benzbromarone affects the expression of ITIH4 mRNA CTD PMID:19483382 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708
JBrowse link
G Iyd iodotyrosine deiodinase decreases activity ISO Benzbromarone results in decreased activity of IYD protein CTD PMID:24012475 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Jak1 Janus kinase 1 affects expression EXP Benzbromarone affects the expression of JAK1 mRNA CTD PMID:19483382 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Kdelr2 KDEL endoplasmic reticulum protein retention receptor 2 affects expression EXP Benzbromarone affects the expression of KDELR2 mRNA CTD PMID:19483382 NCBI chr12:11,138,820...11,157,117
Ensembl chr12:11,138,820...11,157,153
JBrowse link
G Kdr kinase insert domain receptor affects expression EXP Benzbromarone affects the expression of KDR mRNA CTD PMID:19483382 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018
JBrowse link
G Krt8 keratin 8 affects expression EXP Benzbromarone affects the expression of KRT8 mRNA CTD PMID:19483382 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lcat lecithin cholesterol acyltransferase affects expression EXP Benzbromarone affects the expression of LCAT mRNA CTD PMID:19483382 NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
JBrowse link
G Lcmt1 leucine carboxyl methyltransferase 1 affects expression EXP Benzbromarone affects the expression of LCMT1 mRNA CTD PMID:19483382 NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112
JBrowse link
G Lipc lipase C, hepatic type affects expression EXP Benzbromarone affects the expression of LIPC mRNA CTD PMID:19483382 NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
JBrowse link
G LOC102556347 carbonyl reductase [NADPH] 1-like affects expression EXP Benzbromarone affects the expression of CBR1 mRNA CTD PMID:19483382 NCBI chr11:32,892,640...32,895,277
Ensembl chr11:32,857,991...32,895,275
JBrowse link
G Lox lysyl oxidase affects expression EXP Benzbromarone affects the expression of LOX mRNA CTD PMID:19483382 NCBI chr18:45,964,311...46,041,477
Ensembl chr18:45,967,343...46,041,477
JBrowse link
G Lpl lipoprotein lipase increases expression ISO Benzbromarone results in increased expression of LPL protein CTD PMID:18274627 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Lrp3 LDL receptor related protein 3 affects expression EXP Benzbromarone affects the expression of LRP3 mRNA CTD PMID:19483382 NCBI chr 1:87,843,815...87,859,147
Ensembl chr 1:87,844,868...87,859,110
JBrowse link
G Man2b1 mannosidase, alpha, class 2B, member 1 affects expression EXP Benzbromarone affects the expression of MAN2B1 mRNA CTD PMID:19483382 NCBI chr19:23,055,092...23,074,398
Ensembl chr19:23,055,097...23,074,389
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 affects expression EXP Benzbromarone affects the expression of MAP2K2 mRNA CTD PMID:19483382 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243
JBrowse link
G Masp2 MBL associated serine protease 2 affects expression EXP Benzbromarone affects the expression of MASP2 mRNA CTD PMID:19483382 NCBI chr 5:159,035,892...159,049,561
Ensembl chr 5:159,035,911...159,049,580
JBrowse link
G Me1 malic enzyme 1 affects expression EXP Benzbromarone affects the expression of ME1 mRNA CTD PMID:19483382 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mmut methylmalonyl-CoA mutase affects expression EXP Benzbromarone affects the expression of MMUT mRNA CTD PMID:19483382 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046
JBrowse link
G Mro maestro affects expression EXP Benzbromarone affects the expression of MRO mRNA CTD PMID:19483382 NCBI chr18:67,450,186...67,467,593
Ensembl chr18:67,450,595...67,467,044
JBrowse link
G Mrpl2 mitochondrial ribosomal protein L2 affects expression EXP Benzbromarone affects the expression of MRPL2 mRNA CTD PMID:19483382 NCBI chr 9:14,333,233...14,337,006
Ensembl chr 9:14,333,234...14,337,040
JBrowse link
G mrpl9 mitochondrial ribosomal protein L9 affects expression EXP Benzbromarone affects the expression of MRPL9 mRNA CTD PMID:19483382 NCBI chr 2:182,082,012...182,086,758
Ensembl chr 2:182,076,369...182,087,095
JBrowse link
G Mug1 murinoglobulin 1 affects expression EXP Benzbromarone affects the expression of PZP mRNA CTD PMID:19483382 NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
JBrowse link
G Myadm myeloid-associated differentiation marker affects expression EXP Benzbromarone affects the expression of MYADM mRNA CTD PMID:19483382 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035
JBrowse link
G Mycbp2 MYC binding protein 2 affects expression EXP Benzbromarone affects the expression of MYCBP2 mRNA CTD PMID:19483382 NCBI chr15:79,937,354...80,175,432
Ensembl chr15:79,937,354...80,175,498
JBrowse link
G Myo1d myosin ID affects expression EXP Benzbromarone affects the expression of MYO1D mRNA CTD PMID:19483382 NCBI chr10:65,489,153...65,765,812
Ensembl chr10:65,489,154...65,766,349
JBrowse link
G Naa38 N(alpha)-acetyltransferase 38, NatC auxiliary subunit affects expression EXP Benzbromarone affects the expression of NAA38 mRNA CTD PMID:19483382 NCBI chr10:54,117,754...54,118,913
Ensembl chr10:54,117,163...54,119,494
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 affects expression EXP Benzbromarone affects the expression of NAP1L1 mRNA CTD PMID:19483382 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nat8 N-acetyltransferase 8 affects expression EXP Benzbromarone affects the expression of NAT8 mRNA CTD PMID:19483382 NCBI chr 4:118,279,521...118,284,671
Ensembl chr 4:118,270,954...118,281,763
JBrowse link
G Ndrg2 NDRG family member 2 affects expression EXP Benzbromarone affects the expression of NDRG2 mRNA CTD PMID:19483382 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Ndufs5 NADH:ubiquinone oxidoreductase subunit S5 affects expression EXP Benzbromarone affects the expression of NDUFS5 mRNA CTD PMID:19483382 NCBI chr 5:135,974,029...135,979,705
Ensembl chr 5:135,974,034...135,979,603
JBrowse link
G Ndufv3 NADH:ubiquinone oxidoreductase subunit V3 affects expression EXP Benzbromarone affects the expression of NDUFV3 mRNA CTD PMID:19483382 NCBI chr20:9,612,462...9,621,622
Ensembl chr20:9,612,431...9,623,074
JBrowse link
G Neu2 neuraminidase 2 affects expression EXP Benzbromarone affects the expression of NEU2 mRNA CTD PMID:19483382 NCBI chr 9:88,218,494...88,267,356
Ensembl chr 9:88,249,135...88,267,355
JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 affects expression EXP Benzbromarone affects the expression of NFX1 mRNA CTD PMID:19483382 NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912
JBrowse link
G Nipal2 NIPA-like domain containing 2 affects expression EXP Benzbromarone affects the expression of NIPAL2 mRNA CTD PMID:19483382 NCBI chr 7:65,774,477...65,884,807
Ensembl chr 7:65,774,477...65,884,807
JBrowse link
G Nit1 nitrilase 1 affects expression EXP Benzbromarone affects the expression of NIT1 mRNA CTD PMID:19483382 NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 affects expression EXP Benzbromarone affects the expression of NME2 mRNA CTD PMID:19483382 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects expression EXP Benzbromarone affects the expression of NR1I3 mRNA CTD PMID:19483382 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 affects expression EXP Benzbromarone affects the expression of NR3C1 mRNA CTD PMID:19483382 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Oaf out at first homolog affects expression EXP Benzbromarone affects the expression of OAF mRNA CTD PMID:19483382 NCBI chr 8:43,594,362...43,612,334
Ensembl chr 8:43,594,363...43,612,334
JBrowse link
G Obp3 alpha-2u globulin PGCL4 affects expression EXP Benzbromarone affects the expression of OBP3 mRNA CTD PMID:19483382 NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757
JBrowse link
G Ogdh oxoglutarate dehydrogenase affects expression EXP Benzbromarone affects the expression of OGDH mRNA CTD PMID:19483382 NCBI chr14:81,150,021...81,217,479
Ensembl chr14:81,150,091...81,217,479
JBrowse link
G Olr59 olfactory receptor 59 affects expression EXP Benzbromarone affects the expression of OLR59 mRNA CTD PMID:19483382 NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179
JBrowse link
G Ostc oligosaccharyltransferase complex non-catalytic subunit affects expression EXP Benzbromarone affects the expression of OSTC mRNA CTD PMID:19483382 NCBI chr 2:219,250,549...219,266,076
Ensembl chr 2:219,236,952...219,266,107
JBrowse link
G Otc ornithine transcarbamylase affects expression EXP Benzbromarone affects the expression of OTC mRNA CTD PMID:19483382 NCBI chr  X:12,453,834...12,529,954
Ensembl chr  X:12,453,834...12,566,918
JBrowse link
G Pabpc4 poly(A) binding protein, cytoplasmic 4 affects expression EXP Benzbromarone affects the expression of PABPC4 mRNA CTD PMID:19483382 NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979
JBrowse link
G Paics phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase affects expression EXP Benzbromarone affects the expression of PAICS mRNA CTD PMID:19483382 NCBI chr14:31,199,086...31,232,731
Ensembl chr14:31,173,541...31,232,635
JBrowse link
G Pc pyruvate carboxylase affects expression EXP Benzbromarone affects the expression of PCX mRNA CTD PMID:19483382 NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
JBrowse link
G Pccb propionyl-CoA carboxylase subunit beta affects expression EXP Benzbromarone affects the expression of PCCB mRNA CTD PMID:19483382 NCBI chr 8:101,591,218...101,641,213
Ensembl chr 8:101,590,737...101,641,234
JBrowse link
G Pcsk6 proprotein convertase subtilisin/kexin type 6 affects expression EXP Benzbromarone affects the expression of PCSK6 mRNA CTD PMID:19483382 NCBI chr 1:119,428,978...119,627,626
Ensembl chr 1:119,429,265...119,627,596
JBrowse link
G Pctp phosphatidylcholine transfer protein affects expression EXP Benzbromarone affects the expression of PCTP mRNA CTD PMID:19483382 NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867
JBrowse link
G Pdcl3 phosducin-like 3 affects expression EXP Benzbromarone affects the expression of PDCL3 mRNA CTD PMID:19483382 NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 affects expression EXP Benzbromarone affects the expression of PDIA3 mRNA CTD PMID:19483382 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdia6 protein disulfide isomerase family A, member 6 affects expression EXP Benzbromarone affects the expression of PDIA6 mRNA CTD PMID:19483382 NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613
JBrowse link
G Pex19 peroxisomal biogenesis factor 19 affects expression EXP Benzbromarone affects the expression of PEX19 mRNA CTD PMID:19483382 NCBI chr13:84,592,277...84,608,793
Ensembl chr13:84,592,312...84,608,608
JBrowse link
G Pgam1 phosphoglycerate mutase 1 affects expression EXP Benzbromarone affects the expression of PGAM1 mRNA CTD PMID:19483382 NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452
JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 affects expression EXP Benzbromarone affects the expression of PGRMC1 mRNA CTD PMID:19483382 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682
JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase affects expression EXP Benzbromarone affects the expression of PHYH mRNA CTD PMID:19483382 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409
JBrowse link
G Pigp phosphatidylinositol glycan anchor biosynthesis, class P affects expression EXP Benzbromarone affects the expression of PIGP mRNA CTD PMID:19483382 NCBI chr11:33,682,943...33,689,071
Ensembl chr11:33,682,948...33,689,321
JBrowse link
G Pklr pyruvate kinase L/R affects expression EXP Benzbromarone affects the expression of PKLR mRNA CTD PMID:19483382 NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
JBrowse link
G Plbd1 phospholipase B domain containing 1 affects expression EXP Benzbromarone affects the expression of PLBD1 mRNA CTD PMID:19483382 NCBI chr 4:169,472,983...169,529,277
Ensembl chr 4:169,472,983...169,529,277
JBrowse link
G Plg plasminogen affects expression EXP Benzbromarone affects the expression of PLG mRNA CTD PMID:19483382 NCBI chr 1:48,325,186...48,367,643
Ensembl chr 1:48,325,185...48,367,786
JBrowse link
G Pls3 plastin 3 affects expression EXP Benzbromarone affects the expression of PLS3 mRNA CTD PMID:19483382 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891
JBrowse link
G Pon2 paraoxonase 2 affects expression EXP Benzbromarone affects the expression of PON2 mRNA CTD PMID:19483382 NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression ISO Benzbromarone affects the expression of PPARG mRNA CTD PMID:19048458 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppdpf pancreatic progenitor cell differentiation and proliferation factor affects expression EXP Benzbromarone affects the expression of PPDPF mRNA CTD PMID:19483382 NCBI chr 3:168,299,309...168,301,040
Ensembl chr 3:168,299,791...168,301,036
JBrowse link
G Prdx2 peroxiredoxin 2 affects expression EXP Benzbromarone affects the expression of PRDX2 mRNA CTD PMID:19483382 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prdx6 peroxiredoxin 6 affects expression EXP Benzbromarone affects the expression of PRDX6 mRNA CTD PMID:19483382 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa affects expression EXP Benzbromarone affects the expression of PROC mRNA CTD PMID:19483382 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133
JBrowse link
G Prpsap1 phosphoribosyl pyrophosphate synthetase-associated protein 1 affects expression EXP Benzbromarone affects the expression of PRPSAP1 mRNA CTD PMID:19483382 NCBI chr10:101,701,094...101,750,753
Ensembl chr10:101,701,096...101,750,751
JBrowse link
G Psma6 proteasome 20S subunit alpha 6 affects expression EXP Benzbromarone affects the expression of PSMA6 mRNA CTD PMID:19483382 NCBI chr 6:72,765,534...72,796,554
Ensembl chr 6:72,765,473...72,796,554
JBrowse link
G Psmb1 proteasome 20S subunit beta 1 affects expression EXP Benzbromarone affects the expression of PSMB1 mRNA CTD PMID:19483382 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560
JBrowse link
G Psmb3 proteasome 20S subunit beta 3 affects expression EXP Benzbromarone affects the expression of PSMB3 mRNA CTD PMID:19483382 NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
JBrowse link
G Psmc1 proteasome 26S subunit, ATPase 1 affects expression EXP Benzbromarone affects the expression of PSMC1 mRNA CTD PMID:19483382 NCBI chr 6:119,392,833...119,405,233
Ensembl chr 6:119,392,855...119,410,123
JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 affects expression EXP Benzbromarone affects the expression of PSMC3 mRNA CTD PMID:19483382 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 affects expression EXP Benzbromarone affects the expression of PSMC5 mRNA CTD PMID:19483382 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135
JBrowse link
G Psmd1 proteasome 26S subunit, non-ATPase 1 affects expression EXP Benzbromarone affects the expression of PSMD1 mRNA CTD PMID:19483382 NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211
JBrowse link
G Psmd4 proteasome 26S subunit ubiquitin receptor, non-ATPase 4 affects expression EXP Benzbromarone affects the expression of PSMD4 mRNA CTD PMID:19483382 NCBI chr 2:182,598,934...182,608,250
Ensembl chr 2:182,598,934...182,608,194
JBrowse link
G Ptms parathymosin affects expression EXP Benzbromarone affects the expression of PTMS mRNA CTD PMID:19483382 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F affects expression EXP Benzbromarone affects the expression of PTPRF mRNA CTD PMID:19483382 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
JBrowse link
G Pttg1ip PTTG1 interacting protein affects expression EXP Benzbromarone affects the expression of PTTG1IP mRNA CTD PMID:19483382 NCBI chr20:11,030,013...11,047,742
Ensembl chr20:11,030,015...11,047,316
JBrowse link
G Pygl glycogen phosphorylase L affects expression EXP Benzbromarone affects the expression of PYGL mRNA CTD PMID:19483382 NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310
JBrowse link
G Rab5if RAB5 interacting factor affects expression EXP Benzbromarone affects the expression of RAB5IF mRNA CTD PMID:19483382 NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012
JBrowse link
G Rida reactive intermediate imine deaminase A homolog affects expression EXP Benzbromarone affects the expression of RIDA mRNA CTD PMID:19483382 NCBI chr 7:65,691,429...65,705,257
Ensembl chr 7:65,691,435...65,705,716
JBrowse link
G Rnase4 ribonuclease A family member 4 affects expression EXP Benzbromarone affects the expression of RNASE4 mRNA CTD PMID:19483382 NCBI chr15:24,312,765...24,330,116
Ensembl chr15:24,312,464...24,330,117
JBrowse link
G Rnf103 ring finger protein 103 affects expression EXP Benzbromarone affects the expression of RNF103 mRNA CTD PMID:19483382 NCBI chr 4:103,526,456...103,542,529
Ensembl chr 4:103,526,502...103,555,919
JBrowse link
G Rnps1 RNA binding protein with serine rich domain 1 affects expression EXP Benzbromarone affects the expression of RNPS1 mRNA CTD PMID:19483382 NCBI chr10:13,445,516...13,455,858
Ensembl chr10:13,445,653...13,455,858
JBrowse link
G Rpl11 ribosomal protein L11 affects expression EXP Benzbromarone affects the expression of RPL11 mRNA CTD PMID:19483382 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
JBrowse link
G Rpl13 ribosomal protein L13 affects expression EXP Benzbromarone affects the expression of RPL13 mRNA CTD PMID:19483382 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl15 ribosomal protein L15 affects expression EXP Benzbromarone affects the expression of RPL15 mRNA CTD PMID:19483382 NCBI chr15:7,503,883...7,507,166
Ensembl chr15:7,503,883...7,507,165
JBrowse link
G Rpl17 ribosomal protein L17 affects expression EXP Benzbromarone affects the expression of RPL17 mRNA CTD PMID:19483382 NCBI chr18:68,581,147...68,584,253
Ensembl chr18:68,581,098...68,584,253
JBrowse link
G Rpl23 ribosomal protein L23 affects expression EXP Benzbromarone affects the expression of RPL23 mRNA CTD PMID:19483382 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl3 ribosomal protein L3 affects expression EXP Benzbromarone affects the expression of RPL3 mRNA CTD PMID:19483382 NCBI chr 7:111,622,257...111,627,639
Ensembl chr 7:111,621,610...111,636,468
JBrowse link
G Rpl32 ribosomal protein L32 affects expression EXP Benzbromarone affects the expression of RPL32 mRNA CTD PMID:19483382 NCBI chr 4:148,864,048...148,867,612
Ensembl chr 4:148,864,044...148,867,612
JBrowse link
G Rpl4 ribosomal protein L4 affects expression EXP Benzbromarone affects the expression of RPL4 mRNA CTD PMID:19483382 NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
JBrowse link
G Rpn2 ribophorin II affects expression EXP Benzbromarone affects the expression of RPN2 mRNA CTD PMID:19483382 NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543
JBrowse link
G Rps14 ribosomal protein S14 affects expression EXP Benzbromarone affects the expression of RPS14 mRNA CTD PMID:19483382 NCBI chr18:54,227,854...54,232,638
Ensembl chr18:54,227,854...54,233,166
JBrowse link
G Rps18 ribosomal protein S18 affects expression EXP Benzbromarone affects the expression of RPS18 mRNA CTD PMID:19483382 NCBI chr20:4,931,427...4,935,538
Ensembl chr10:101,204,500...101,205,146
Ensembl chr20:101,204,500...101,205,146
JBrowse link
G Rps19 ribosomal protein S19 affects expression EXP Benzbromarone affects the expression of RPS19 mRNA CTD PMID:19483382 NCBI chr 1:80,480,718...80,486,511
Ensembl chr 1:80,480,951...80,486,508
JBrowse link
G Rps20 ribosomal protein S20 affects expression EXP Benzbromarone affects the expression of RPS20 mRNA CTD PMID:19483382 NCBI chr 5:16,819,313...16,820,475
Ensembl chr 5:16,819,304...16,820,475
JBrowse link
G Rps3a ribosomal protein S3a affects expression EXP Benzbromarone affects the expression of RPS3A mRNA CTD PMID:19483382 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G Rps6 ribosomal protein S6 affects expression EXP Benzbromarone affects the expression of RPS6 mRNA CTD PMID:19483382 NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602
Ensembl chr 5:101,371,136...101,374,602
JBrowse link
G Rps8 ribosomal protein S8 affects expression EXP Benzbromarone affects the expression of RPS8 mRNA CTD PMID:19483382 NCBI chr 5:130,630,362...130,632,932
Ensembl chr 5:130,629,716...130,633,268
JBrowse link
G Rras2 RAS related 2 affects expression EXP Benzbromarone affects the expression of RRAS2 mRNA CTD PMID:19483382 NCBI chr 1:168,233,693...168,303,111
Ensembl chr 1:168,233,693...168,303,111
JBrowse link
G RT1-S3 RT1 class Ib, locus S3 affects expression EXP Benzbromarone affects the expression of RT1-S3 mRNA CTD PMID:19483382 NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 affects expression EXP Benzbromarone affects the expression of S1PR1 mRNA CTD PMID:19483382 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing affects expression EXP Benzbromarone affects the expression of SBSPON mRNA CTD PMID:19483382 NCBI chr 5:3,402,727...3,436,448
Ensembl chr 5:3,402,648...3,435,420
JBrowse link
G Sdc2 syndecan 2 affects expression EXP Benzbromarone affects the expression of SDC2 mRNA CTD PMID:19483382 NCBI chr 7:64,127,185...64,239,885
Ensembl chr 7:64,127,110...64,241,081
JBrowse link
G Sdhc succinate dehydrogenase complex subunit C affects expression EXP Benzbromarone affects the expression of SDHC mRNA CTD PMID:19483382 NCBI chr13:83,544,652...83,565,560
Ensembl chr13:83,544,652...83,566,253
JBrowse link
G Sdhd succinate dehydrogenase complex subunit D affects expression EXP Benzbromarone affects the expression of SDHD mRNA CTD PMID:19483382 NCBI chr 8:50,944,717...50,954,298
Ensembl chr 8:50,944,704...50,954,238
JBrowse link
G Serinc3 serine incorporator 3 affects expression EXP Benzbromarone affects the expression of SERINC3 mRNA CTD PMID:19483382 NCBI chr 3:152,301,882...152,321,327
Ensembl chr 3:152,301,772...152,321,808
JBrowse link
G Serpina1 serpin family A member 1 affects expression EXP Benzbromarone affects the expression of SERPINA1 mRNA CTD PMID:19483382 NCBI chr 6:122,866,314...122,888,339
Ensembl chr 6:122,866,312...122,888,339
JBrowse link
G Serpina10 serpin family A member 10 affects expression EXP Benzbromarone affects the expression of SERPINA10 mRNA CTD PMID:19483382 NCBI chr 6:122,756,106...122,764,544
Ensembl chr 6:122,756,108...122,764,544
JBrowse link
G Serpina4 serpin family A member 4 affects expression EXP Benzbromarone affects the expression of SERPINA4 mRNA CTD PMID:19483382 NCBI chr 6:122,999,970...123,009,083
Ensembl chr 6:122,999,900...123,009,082
JBrowse link
G Serpinf2 serpin family F member 2 affects expression EXP Benzbromarone affects the expression of SERPINF2 mRNA CTD PMID:19483382 NCBI chr10:60,272,400...60,280,506
Ensembl chr10:60,272,400...60,281,243
JBrowse link
G Sfxn1 sideroflexin 1 affects expression EXP Benzbromarone affects the expression of SFXN1 mRNA CTD PMID:19483382 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529
JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 affects expression EXP Benzbromarone affects the expression of SHMT2 mRNA CTD PMID:19483382 NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236
JBrowse link
G Slc22a1 solute carrier family 22 member 1 affects expression EXP Benzbromarone affects the expression of SLC22A1 mRNA CTD PMID:19483382 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a12 solute carrier family 22 member 12 affects activity
decreases activity
multiple interactions
affects response to substance
ISO
EXP
Benzbromarone affects the activity of SLC22A12 protein
Benzbromarone results in decreased activity of SLC22A12 protein
Benzbromarone inhibits the reaction [SLC22A12 protein affects the transport of Uric Acid]
SLC22A12 protein affects the susceptibility to Benzbromarone
Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Oxypurinol]; Benzbromarone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid]
CTD PMID:14694169 PMID:14747372 PMID:16135657 PMID:18670416 PMID:20486468 More... NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions ISO Benzbromarone inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid] CTD PMID:12472777 NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc23a1 solute carrier family 23 member 1 affects expression EXP Benzbromarone affects the expression of SLC23A1 mRNA CTD PMID:19483382 NCBI chr18:27,214,940...27,230,564
Ensembl chr18:27,216,281...27,230,697
JBrowse link
G Slc25a13 solute carrier family 25 member 13 affects expression EXP Benzbromarone affects the expression of SLC25A13 mRNA CTD PMID:19483382 NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902
JBrowse link
G Slc25a3 solute carrier family 25 member 3 affects expression EXP Benzbromarone affects the expression of SLC25A3 mRNA CTD PMID:19483382 NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Slc27a2 solute carrier family 27 member 2 affects expression EXP Benzbromarone affects the expression of SLC27A2 mRNA CTD PMID:19483382 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
JBrowse link
G Slc2a9 solute carrier family 2 member 9 multiple interactions ISO Benzbromarone inhibits the reaction [SLC2A9 protein results in increased uptake of Uric Acid]
Benzbromarone inhibits the reaction [SLC2A9 protein alternative form results in increased transport of Uric Acid]
CTD PMID:18842065 PMID:19587147 NCBI chr14:72,328,334...72,461,981
Ensembl chr14:72,328,320...72,461,981
JBrowse link
G Slc39a8 solute carrier family 39 member 8 affects expression EXP Benzbromarone affects the expression of SLC39A8 mRNA CTD PMID:19483382 NCBI chr 2:224,171,787...224,319,326
Ensembl chr 2:224,256,654...224,319,129
JBrowse link
G Slc46a1 solute carrier family 46 member 1 affects expression EXP Benzbromarone affects the expression of SLC46A1 mRNA CTD PMID:19483382 NCBI chr10:63,361,504...63,367,940
Ensembl chr10:63,361,486...63,368,848
JBrowse link
G Slc66a2 solute carrier family 66 member 2 affects expression EXP Benzbromarone affects the expression of SLC66A2 mRNA CTD PMID:19483382 NCBI chr18:73,702,472...73,739,678
Ensembl chr18:73,702,564...73,739,676
JBrowse link
G Slc6a6 solute carrier family 6 member 6 affects expression EXP Benzbromarone affects the expression of SLC6A6 mRNA CTD PMID:19483382 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875
JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO Benzbromarone results in increased expression of SOD2 mRNA CTD PMID:25108121 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sppl2a signal peptide peptidase-like 2A affects expression EXP Benzbromarone affects the expression of SPPL2A mRNA CTD PMID:19483382 NCBI chr 3:114,149,337...114,193,408
Ensembl chr 3:114,151,069...114,193,264
JBrowse link
G Srm spermidine synthase affects expression EXP Benzbromarone affects the expression of SRM mRNA CTD PMID:19483382 NCBI chr 5:159,025,919...159,029,076
Ensembl chr 5:159,025,873...159,029,405
JBrowse link
G Srprb SRP receptor subunit beta affects expression EXP Benzbromarone affects the expression of SRPRB mRNA CTD PMID:19483382 NCBI chr 8:103,768,685...103,782,632 JBrowse link
G Ssx2ip SSX family member 2 interacting protein affects expression EXP Benzbromarone affects the expression of SSX2IP mRNA CTD PMID:19483382 NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745
JBrowse link
G St3gal6 ST3 beta-galactoside alpha-2,3-sialyltransferase 6 affects expression EXP Benzbromarone affects the expression of ST3GAL6 mRNA CTD PMID:19483382 NCBI chr11:42,061,282...42,121,801
Ensembl chr11:42,077,621...42,121,776
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 affects expression EXP Benzbromarone affects the expression of ST6GAL1 mRNA CTD PMID:19483382 NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310
JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha affects expression EXP Benzbromarone affects the expression of SUCLG1 mRNA CTD PMID:19483382 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600
JBrowse link
G Surf4 surfeit 4 affects expression EXP Benzbromarone affects the expression of SURF4 mRNA CTD PMID:19483382 NCBI chr 3:10,248,360...10,261,537
Ensembl chr 3:10,241,837...10,263,315
JBrowse link
G Synj2bp synaptojanin 2 binding protein affects expression EXP Benzbromarone affects the expression of SYNJ2BP mRNA CTD PMID:19483382 NCBI chr 6:101,189,714...101,227,400
Ensembl chr 6:101,189,714...101,227,406
JBrowse link
G Tgfbi transforming growth factor, beta induced affects expression EXP Benzbromarone affects the expression of TGFBI mRNA CTD PMID:19483382 NCBI chr17:7,955,603...7,984,903
Ensembl chr17:7,955,603...7,985,240
JBrowse link
G Thnsl2 threonine synthase-like 2 affects expression EXP Benzbromarone affects the expression of THNSL2 mRNA CTD PMID:19483382 NCBI chr 4:103,112,974...103,132,122
Ensembl chr 4:103,112,963...103,132,017
JBrowse link
G Timm21 translocase of inner mitochondrial membrane 21 affects expression EXP Benzbromarone affects the expression of TIMM21 mRNA CTD PMID:19483382 NCBI chr18:78,314,900...78,319,362
Ensembl chr18:78,314,909...78,319,454
JBrowse link
G Tkfc triokinase and FMN cyclase affects expression EXP Benzbromarone affects the expression of TKFC mRNA CTD PMID:19483382 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737
JBrowse link
G Tmbim1 transmembrane BAX inhibitor motif containing 1 affects expression EXP Benzbromarone affects the expression of TMBIM1 mRNA CTD PMID:19483382 NCBI chr 9:75,871,835...75,889,366
Ensembl chr 9:75,871,835...75,889,069
JBrowse link
G Tmco1 transmembrane and coiled-coil domains 1 affects expression EXP Benzbromarone affects the expression of TMCO1 mRNA CTD PMID:19483382 NCBI chr13:79,460,229...79,483,557
Ensembl chr13:79,460,135...79,483,555
JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 affects expression EXP Benzbromarone affects the expression of TMED2 mRNA CTD PMID:19483382 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903
JBrowse link
G Tmed7 transmembrane p24 trafficking protein 7 affects expression EXP Benzbromarone affects the expression of TMED7 mRNA CTD PMID:19483382 NCBI chr18:39,318,564...39,325,640
Ensembl chr18:39,297,351...39,325,640
JBrowse link
G Tmem123 transmembrane protein 123 affects expression EXP Benzbromarone affects the expression of TMEM123 mRNA CTD PMID:19483382 NCBI chr 8:4,922,098...4,952,228
Ensembl chr 8:4,922,098...4,952,224
JBrowse link
G Tmem97 transmembrane protein 97 affects expression EXP Benzbromarone affects the expression of TMEM97 mRNA CTD PMID:19483382 NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression ISO Benzbromarone results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715
JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions
ISO Benzbromarone results in increased expression of TNF protein
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Benzbromarone
CTD PMID:19362101 PMID:19933411 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txn1 thioredoxin 1 affects expression EXP Benzbromarone affects the expression of TXN1 mRNA CTD PMID:19483382 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txnl1 thioredoxin-like 1 affects expression EXP Benzbromarone affects the expression of TXNL1 mRNA CTD PMID:19483382 NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 affects expression EXP Benzbromarone affects the expression of UBA52 mRNA CTD PMID:19483382 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807
JBrowse link
G Ube2n ubiquitin-conjugating enzyme E2N affects expression EXP Benzbromarone affects the expression of UBE2N mRNA CTD PMID:19483382 NCBI chr 7:30,154,330...30,184,373
Ensembl chr 7:30,154,616...30,184,355
JBrowse link
G Ufd1 ubiquitin recognition factor in ER associated degradation 1 affects expression EXP Benzbromarone affects the expression of UFD1 mRNA CTD PMID:19483382 NCBI chr11:82,161,618...82,185,107
Ensembl chr11:82,161,619...82,185,087
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 affects expression EXP Benzbromarone affects the expression of UGT1A1 mRNA CTD PMID:19483382 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Uhrf1bp1l UHRF1 binding protein 1-like affects expression EXP Benzbromarone affects the expression of UHRF1BP1L mRNA CTD PMID:19483382 NCBI chr 7:24,181,635...24,261,720
Ensembl chr 7:24,181,644...24,261,720
JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression EXP Benzbromarone affects the expression of UQCR11 mRNA CTD PMID:19483382 NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750
JBrowse link
G Vnn1 vanin 1 affects expression EXP Benzbromarone affects the expression of VNN1 mRNA CTD PMID:19483382 NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
JBrowse link
G Wdr26 WD repeat domain 26 affects expression EXP Benzbromarone affects the expression of WDR26 mRNA CTD PMID:19483382 NCBI chr13:92,930,282...92,972,061
Ensembl chr13:92,930,285...92,977,295
JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma affects expression EXP Benzbromarone affects the expression of YWHAG mRNA CTD PMID:19483382 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827
JBrowse link
G Zdhhc23 zinc finger DHHC-type palmitoyltransferase 23 affects expression EXP Benzbromarone affects the expression of ZDHHC23 mRNA CTD PMID:19483382 NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
JBrowse link
G Zwint ZW10 interacting kinetochore protein affects expression EXP Benzbromarone affects the expression of ZWINT mRNA CTD PMID:19483382 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link
desmopressin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aqp2 aquaporin 2 increases expression
multiple interactions
ISO
EXP
Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA; Deamino Arginine Vasopressin results in increased expression of AQP2 protein
Deamino Arginine Vasopressin inhibits the reaction [aluminum lactate results in decreased expression of AQP2 protein]; Deamino Arginine Vasopressin results in increased expression of and results in increased uptake of and results in increased ubiquitination of AQP2 protein
Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 mRNA]; Lithium inhibits the reaction [Deamino Arginine Vasopressin results in increased expression of AQP2 protein]
CTD PMID:16495377 PMID:16675087 PMID:21734099 NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468
JBrowse link
G Avp arginine vasopressin multiple interactions ISO [Atrazine affects the metabolism of AVP protein] which results in increased abundance of Deamino Arginine Vasopressin CTD PMID:33485040 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
JBrowse link
G Avpr2 arginine vasopressin receptor 2 multiple interactions EXP
ISO
[Deamino Arginine Vasopressin binds to and results in increased activity of AVPR2 protein] which results in decreased activity of 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid CTD PMID:1399968 PMID:15685210 NCBI chr  X:151,633,501...151,636,000
Ensembl chr  X:151,633,522...151,635,989
JBrowse link
G Cftr CF transmembrane conductance regulator increases activity ISO Deamino Arginine Vasopressin results in increased activity of CFTR protein CTD PMID:15685210 NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756
JBrowse link
G Cul5 cullin 5 increases expression EXP Deamino Arginine Vasopressin results in increased expression of CUL5 protein CTD PMID:21734099 NCBI chr 8:54,012,963...54,066,751
Ensembl chr 8:54,016,006...54,066,666
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO GSK3B protein affects the reaction [Deamino Arginine Vasopressin results in increased abundance of Cyclic AMP] CTD PMID:20056751 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Myl9 myosin light chain 9 increases phosphorylation
multiple interactions
EXP Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein
ML 7 inhibits the reaction [Deamino Arginine Vasopressin results in increased phosphorylation of MYL9 protein]
CTD PMID:15347643 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase increases expression EXP Deamino Arginine Vasopressin results in increased expression of NEDD4 protein CTD PMID:21734099 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1B mRNA CTD PMID:11711512 NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma increases expression EXP Deamino Arginine Vasopressin results in increased expression of SCNN1G mRNA CTD PMID:11711512 NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
JBrowse link
G Vwf von Willebrand factor increases activity
increases secretion
ISO Deamino Arginine Vasopressin results in increased activity of VWF protein
Deamino Arginine Vasopressin results in increased secretion of VWF protein
CTD PMID:1837767 PMID:2738447 PMID:3259400 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539
JBrowse link
E3040 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions ISO [SLCO1B1 protein co-treated with ABCC2 protein] results in increased transport of E 3040 analog CTD PMID:19628752 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 affects export ISO ABCG2 protein affects the export of E 3040 analog CTD PMID:15598971 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO E 3040 inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid] CTD PMID:21272127 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
nitroxoline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein] CTD PMID:31638783 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Cat catalase multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of CAT protein] CTD PMID:31638783 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of and affects the localization of FOXO3 protein]; nitroxoline results in decreased expression of and affects the localization of FOXO3 protein CTD PMID:31638783 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G Metap2 methionyl aminopeptidase 2 decreases activity ISO nitroxoline results in decreased activity of METAP2 protein CTD PMID:21088277 NCBI chr 7:28,412,771...28,440,458
Ensembl chr 7:28,411,608...28,440,434
JBrowse link
G Sirt1 sirtuin 1 multiple interactions
decreases expression
ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]
nitroxoline results in decreased expression of SIRT1 protein
CTD PMID:31638783 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of SOD1 protein] CTD PMID:31638783 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO nitroxoline inhibits the reaction [Hydrogen Peroxide results in decreased expression of SOD2 protein] CTD PMID:31638783 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
probenecid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca8 ATP binding cassette subfamily A member 8 multiple interactions ISO Probenecid inhibits the reaction [ABCA8 protein results in increased uptake of estradiol-17 beta-glucuronide] CTD PMID:12379217 NCBI chr10:94,917,520...94,991,199
Ensembl chr10:94,917,520...94,990,988
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
affects activity
EXP
ISO
Probenecid results in decreased activity of ABCC1 protein
[Probenecid results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine
Probenecid affects the activity of ABCC1 protein
[Probenecid results in decreased activity of ABCC1 protein] which results in decreased export of 10-nitro-oleic acid metabolite; Probenecid affects the reaction [ABCC1 protein results in increased transport of Valproic Acid]; Probenecid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein]
CTD PMID:9096673 PMID:9334814 PMID:12893836 PMID:15066675 PMID:15585369 More... NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases export
multiple interactions
increases activity
EXP
ISO
ABCC2 protein results in increased export of Probenecid
Probenecid inhibits the reaction [ABCC2 protein affects the export of 6-carboxyfluorescein]; Probenecid inhibits the reaction [ABCC2 protein results in increased export of 5(6)-carboxy-2',7'-dichlorofluorescein analog]; Probenecid promotes the reaction [ABCC2 protein affects the transport of docetaxel]; Probenecid promotes the reaction [ABCC2 protein affects the transport of estradiol-17 beta-glucuronide]; Probenecid promotes the reaction [ABCC2 protein affects the transport of Etoposide]; Probenecid promotes the reaction [ABCC2 protein affects the transport of Paclitaxel]; Probenecid promotes the reaction [ABCC2 protein affects the transport of Vinblastine]; Probenecid promotes the reaction [ABCC2 protein results in decreased susceptibility to Paclitaxel]
[Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of resveratrol metabolite; [Probenecid results in decreased activity of ABCC2 protein] which results in decreased secretion of Rosuvastatin Calcium
Probenecid results in increased activity of ABCC2 protein
CTD PMID:11477083 PMID:12608533 PMID:12704183 PMID:15849751 PMID:15904671 More... NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO Probenecid inhibits the reaction [ABCC3 protein affects the transport of estradiol-17 beta-glucuronide] CTD PMID:12704183 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO Probenecid inhibits the reaction [ABCC4 protein results in increased transport of Cyclic GMP]
Probenecid affects the reaction [ABCC4 protein affects the uptake of Cyclic AMP analog]
CTD PMID:11856762 PMID:28587784 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions ISO Probenecid inhibits the reaction [ABCC5 protein results in decreased susceptibility to Thioguanine] CTD PMID:15897250 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions ISO Probenecid inhibits the reaction [ABCC6 protein affects the transport of N-ethylmaleimide-S-glutathione] CTD PMID:11880368 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in increased expression of ABCG2 protein] CTD PMID:22865646 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of BAX protein] CTD PMID:24768735 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of BCL2 protein] CTD PMID:24768735 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Card10 caspase recruitment domain family, member 10 multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CARD10 mRNA CTD PMID:25406165 NCBI chr 7:110,330,460...110,371,551
Ensembl chr 7:110,330,408...110,359,224
JBrowse link
G Casp1 caspase 1 multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CASP1 mRNA]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CASP1 mRNA CTD PMID:25406165 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 mRNA]; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CASP9 protein] CTD PMID:24768735 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased activity of CAT protein] CTD PMID:24768735 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
increases expression
EXP
ISO
Probenecid inhibits the reaction [Uric Acid results in increased expression of CCL2 protein]
Probenecid analog results in increased expression of CCL2 mRNA
1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CCL2 mRNA]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of CCL2 mRNA
CTD PMID:16113518 PMID:24104198 PMID:25406165 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO Probenecid promotes the reaction [10-nitro-oleic acid results in decreased expression of CCND1 protein] CTD PMID:29158255 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO Probenecid promotes the reaction [10-nitro-oleic acid results in increased expression of CDKN1A protein] CTD PMID:29158255 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cox7c cytochrome c oxidase subunit 7C multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of COX7C mRNA] CTD PMID:24768735 NCBI chr 2:16,841,771...16,843,796
Ensembl chr 2:16,840,837...16,843,760
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions ISO Probenecid inhibits the reaction [4-cresol sulfate results in increased expression of CYBA mRNA] CTD PMID:23325087 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein; geraniol inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of CYC1 protein] CTD PMID:24768735 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 multiple interactions ISO Probenecid promotes the reaction [CYP2C8 protein affects the chemical synthesis of carbamazepine epoxide]; Probenecid promotes the reaction [CYP2C8 protein affects the metabolism of Carbamazepine] CTD PMID:15915352
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
multiple interactions
ISO Probenecid results in decreased expression of CYP3A4 mRNA
Probenecid promotes the reaction [CYP3A4 protein affects the chemical synthesis of carbamazepine epoxide]; Probenecid promotes the reaction [CYP3A4 protein affects the metabolism of Carbamazepine]
CTD PMID:15915352 PMID:16837568 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Fadd Fas associated via death domain multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of FADD mRNA CTD PMID:25406165 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Faslg Fas ligand multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of FASL mRNA CTD PMID:25406165 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of GFAP protein; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in increased expression of GFAP protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of GFAP protein] CTD PMID:25064079 PMID:28807673 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gpr55 G protein-coupled receptor 55 multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of GPR55 protein CTD PMID:28807673 NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions ISO Probenecid inhibits the reaction [cidofovir results in increased secretion of HAVCR1 protein] CTD PMID:29738843 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]; 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of IL1A mRNA CTD PMID:25406165 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [Probenecid binds to Dextrans] inhibits the reaction [Dextran Sulfate results in increased secretion of MPO protein] CTD PMID:30102254 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO Probenecid inhibits the reaction [4-cresol sulfate results in increased expression of NOX4 mRNA] CTD PMID:23325087 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] affects the localization of and results in decreased expression of NR4A2 protein]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] affects the localization of and results in decreased expression of NR4A2 protein CTD PMID:25406165 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Ocln occludin multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of OCLN protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of OCLN protein] CTD PMID:25064079 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Panx1 Pannexin 1 decreases activity
multiple interactions
ISO Probenecid results in decreased activity of PANX1 protein
Probenecid inhibits the reaction [PANX1 protein results in increased export of Adenosine Triphosphate]
CTD PMID:19023039 PMID:19213873 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO Probenecid promotes the reaction [10-nitro-oleic acid results in increased cleavage of PARP1 protein] CTD PMID:29158255 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ren renin multiple interactions ISO Probenecid inhibits the reaction [Bumetanide results in increased secretion of REN protein] CTD PMID:7040495 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC18A2 protein CTD PMID:19653878 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc22a1 solute carrier family 22 member 1 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A1 protein] CTD PMID:22865646 PMID:22967667 NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions
affects activity
ISO Probenecid inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid]
Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC22A12 protein]; Probenecid inhibits the reaction [SLC22A12 protein affects the transport of Uric Acid]
Probenecid affects the activity of SLC22A12 protein
CTD PMID:14694169 PMID:14747372 PMID:21272127 PMID:22865646 PMID:22967667 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A2 protein] CTD PMID:22865646 PMID:22967667 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Slc22a20 solute carrier family 22 member 20 multiple interactions ISO Probenecid inhibits the reaction [SLC22A20 protein results in increased uptake of estrone sulfate] CTD PMID:16478971 NCBI chr 1:203,257,374...203,273,848
Ensembl chr 1:203,257,374...203,273,822
JBrowse link
G Slc22a25 solute carrier family 22, member 25 multiple interactions
decreases activity
ISO Probenecid inhibits the reaction [SLC22A9 protein results in increased import of estrone sulfate]; Probenecid inhibits the reaction [SLC22A9 protein results in increased uptake of estrone sulfate]
Probenecid results in decreased activity of SLC22A9 protein
CTD PMID:17132213 PMID:28629854 NCBI chr 1:205,338,698...205,498,486
Ensembl chr 1:205,338,699...205,433,085
JBrowse link
G Slc22a4 solute carrier family 22 member 4 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A4 protein] CTD PMID:22865646 PMID:22967667 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720
JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A5 protein] CTD PMID:22865646 PMID:22967667 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309
JBrowse link
G Slc22a6 solute carrier family 22 member 6 multiple interactions
decreases activity
ISO
EXP
Probenecid inhibits the reaction [[SLC22A6 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyadenosin-N(6)-yl)aristolactam I]; Probenecid inhibits the reaction [[SLC22A6 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyguanosin-N(2)-yl)aristolactam I]; Probenecid inhibits the reaction [SLC22A6 protein affects the transport of Uric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A6 protein results in increased import of p-Aminohippuric Acid]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-((2-phosphonylmethoxy)ethyl)guanine]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to 9-(S)-(3-hydroxy-2-(phosphonomethoxy)propyl)adenine]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to adefovir]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to N(6)-cyclopropyl-9-(2-phosphonylmethoxyethyl)-2,6-diaminopurine]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to Tenofovir]; Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]]; Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of p-Aminohippuric Acid]
Probenecid results in decreased activity of SLC22A6 protein
Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in decreased expression of SLC22A6 protein]
Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of ochratoxin A]
CTD PMID:10336520 PMID:11602689 PMID:12472777 PMID:12606766 PMID:19643159 More... NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173
JBrowse link
G Slc22a8 solute carrier family 22 member 8 multiple interactions
decreases activity
decreases expression
ISO
EXP
Probenecid inhibits the reaction [[SLC22A8 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyadenosin-N(6)-yl)aristolactam I]; Probenecid inhibits the reaction [[SLC22A8 results in increased uptake of Aristolochic Acids] which results in increased chemical synthesis of 7-(deoxyguanosin-N(2)-yl)aristolactam I]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Cimetidine]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of 6-carboxyfluorescein]; Probenecid inhibits the reaction [SLC22A8 protein results in increased import of estrone sulfate]; Probenecid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]
Probenecid results in decreased activity of SLC22A8 protein
Probenecid results in decreased expression of SLC22A8 mRNA; Probenecid results in decreased expression of SLC22A8 protein
Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Cimetidine]; Probenecid inhibits the reaction [SLC22A8 protein affects the transport of Famotidine]; Probenecid inhibits the reaction [SLC22A8 protein results in increased uptake of estrone sulfate]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Cimetidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Famotidine]; Probenecid promotes the reaction [SLC22A8 protein results in increased uptake of Ranitidine]
CTD PMID:10224140 PMID:11306713 PMID:15319347 PMID:16006492 PMID:19643159 More... NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450
JBrowse link
G Slc2a1 solute carrier family 2 member 1 multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SLC2A1 protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SLC2A1 protein] CTD PMID:25064079 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
JBrowse link
G Slc2a9 solute carrier family 2 member 9 multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 mRNA]; Probenecid inhibits the reaction [potassium oxonate results in increased expression of SLC2A9 protein] CTD PMID:22967667 NCBI chr14:72,328,334...72,461,981
Ensembl chr14:72,328,320...72,461,981
JBrowse link
G Slc5a6 solute carrier family 5 member 6 multiple interactions ISO Probenecid inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712
JBrowse link
G Slc5a8 solute carrier family 5 member 8 decreases activity ISO Probenecid results in decreased activity of SLC5A8 protein CTD PMID:15090606 NCBI chr 7:23,272,891...23,313,811
Ensembl chr 7:23,272,427...23,314,642
JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC6A3 protein]; 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC6A3 protein]; 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC6A3 protein]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of SLC6A3 protein; [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SLC6A3 protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of SLC6A3 protein] CTD PMID:19653878 PMID:25064079 PMID:25406165 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 multiple interactions ISO Probenecid inhibits the reaction [SLCO1B3 protein results in increased uptake of Fluorescein] CTD PMID:27989701 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Tas2r118 taste receptor, type 2, member 118 multiple interactions ISO Probenecid binds to and results in decreased activity of TAS2R16 protein; Probenecid inhibits the reaction [salicin results in increased activity of TAS2R16 protein] CTD PMID:21629661 NCBI chr 4:52,449,208...52,450,107
Ensembl chr 4:52,449,208...52,450,107
JBrowse link
G Tas2r138 taste receptor, type 2, member 138 multiple interactions
decreases activity
ISO Probenecid inhibits the reaction [Phenylthiourea results in increased activity of TAS2R38 protein]; Probenecid inhibits the reaction [Propylthiouracil results in increased activity of TAS2R38 protein]
Probenecid results in decreased activity of TAS2R38 protein
CTD PMID:21629661 NCBI chr 4:69,428,344...69,429,339
Ensembl chr 4:69,428,344...69,429,339
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Probenecid inhibits the reaction [4-cresol sulfate results in increased expression of and results in increased secretion of TGFB1 protein] CTD PMID:23325087 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Th tyrosine hydroxylase multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein]; 1,1-bis(3'-indolyl)-1-(4-hydroxyphenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein]; 1,1-bis(3'-indolyl)-1-(p-anisyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in decreased expression of TH protein CTD PMID:19653878 PMID:25406165 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions ISO [Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of TJP1 protein; Trehalose inhibits the reaction [[Probenecid co-treated with 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine] results in decreased expression of TJP1 protein] CTD PMID:25064079 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO 1,1-bis(3'-indolyl)-1-(4-chlorophenyl)methane inhibits the reaction [[1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA]; [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TLR4 mRNA CTD PMID:25406165 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine co-treated with Probenecid] results in increased expression of TNF mRNA CTD PMID:25406165 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 affects response to substance ISO UGT1A3 affects the susceptibility to Probenecid CTD PMID:17880178 NCBI chr 9:88,791,216...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 affects response to substance ISO UGT1A9 affects the susceptibility to Probenecid CTD PMID:17880178 NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 affects response to substance ISO UGT2B7 affects the susceptibility to Probenecid CTD PMID:17880178 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
G Umod uromodulin multiple interactions ISO Probenecid inhibits the reaction [potassium oxonate results in increased expression of and results in decreased secretion of UMOD protein] CTD PMID:22865646 NCBI chr 1:173,816,341...173,829,681
Ensembl chr 1:173,816,339...173,830,302
JBrowse link
sulfinpyrazone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Sulfinpyrazone inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Sulfinpyrazone results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
ISO
EXP
Sulfinpyrazone results in decreased activity of ABCC1 protein
[Sulfinpyrazone results in decreased activity of ABCC1 protein] which results in increased uptake of Vincristine
CTD PMID:12893836 PMID:15044619 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases activity ISO Sulfinpyrazone results in decreased activity of ABCC2 protein CTD PMID:14569069 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO Sulfinpyrazone results in increased expression of CYP2B6 protein CTD PMID:14977870 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Sulfinpyrazone results in decreased activity of CYP2C8 protein CTD PMID:12464242
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
increases activity
ISO Sulfinpyrazone results in increased expression of CYP3A4 mRNA
Sulfinpyrazone results in increased activity of CYP3A4 protein
CTD PMID:9512926 PMID:10219967 PMID:12065438 PMID:16837568 PMID:17954527 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions ISO Sulfinpyrazone inhibits the reaction [GSTM1 protein results in decreased susceptibility to Vincristine] CTD PMID:15044619 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Sulfinpyrazone inhibits the reaction [GSTP1 protein results in decreased susceptibility to Etoposide] CTD PMID:15999103 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO Sulfinpyrazone binds to and results in increased activity of NR1I2 protein
Sulfinpyrazone results in increased activity of NR1I2 protein
CTD PMID:12065438 PMID:14977870 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Slc22a12 solute carrier family 22 member 12 multiple interactions ISO Sulfinpyrazone inhibits the reaction [SLC22A12 protein results in increased uptake of Uric Acid] CTD PMID:21272127 NCBI chr 1:203,845,039...203,852,496
Ensembl chr 1:203,845,048...203,853,555
JBrowse link

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  CHEBI ontology 20059
    role 20009
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              sulfamethoxydiazine 0
              uricosuric drug + 399
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