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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:leprostatic drug
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Accession:CHEBI:35816 term browser browse the term
Definition:A substance that suppresses Mycobacterium leprae, ameliorates the clinical manifestations of leprosy, and/or reduces the incidence and severity of leprous reactions.
Synonyms:related_synonym: leprostatic;   leprostatic agent;   leprostatic drugs



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clofazimine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases activity ISO Clofazimine results in decreased activity of ABCB11 protein CTD PMID:20829430 PMID:23956101 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha increases expression ISO Clofazimine results in increased expression of ACACA mRNA CTD PMID:31393584 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO Clofazimine results in increased expression of CEBPA protein CTD PMID:31393584 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 decreases expression ISO Clofazimine results in decreased expression of DGAT1 mRNA CTD PMID:31393584 NCBI chr15:76,386,215...76,396,167
Ensembl chr15:76,386,215...76,396,153
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Clofazimine results in increased expression of FAS mRNA CTD PMID:31393584 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions ISO Clofazimine inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 decreases activity ISO Clofazimine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 5:24,524,583...24,556,671
Ensembl chr 5:24,524,587...24,556,602
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma increases expression ISO Clofazimine results in increased expression of PPARG mRNA; Clofazimine results in increased expression of PPARG protein CTD PMID:31393584 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO Clofazimine results in increased expression of SREBF1 mRNA CTD PMID:31393584 NCBI chr11:60,089,910...60,113,407
Ensembl chr11:60,089,915...60,113,407
JBrowse link
G Zfp423 zinc finger protein 423 increases expression ISO Clofazimine results in increased expression of ZFP423 mRNA CTD PMID:31393584 NCBI chr 8:88,388,438...88,688,665
Ensembl chr 8:88,388,438...88,686,223
JBrowse link
dapsone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP-binding cassette, sub-family member 2 decreases expression ISO Dapsone metabolite results in decreased expression of ABCC2 protein CTD PMID:15863252 NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Cat catalase decreases activity ISO Dapsone results in decreased activity of CAT protein CTD PMID:18602405 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions EXP Dapsone inhibits the reaction [Paraquat results in increased expression of CCL3 mRNA] CTD PMID:21765237 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
decreases secretion
ISO [Dapsone co-treated with lipopolysaccharide, E. coli O26-B6] results in decreased expression of CXCL8 mRNA; Dapsone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CXCL8 mRNA]; Dapsone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL8 protein]
Dapsone results in decreased secretion of CXCL8 protein
CTD PMID:11359455 PMID:21436242 PMID:29594315 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of CXCR4 mRNA] CTD PMID:21440447 NCBI chr 1:128,515,936...128,520,036
Ensembl chr 1:128,515,936...128,520,030
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity ISO Dapsone results in increased activity of CYP1A1 protein CTD PMID:12451431 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions ISO CYP2B6 protein results in increased metabolism of and results in increased susceptibility to Dapsone CTD PMID:19998329 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 increases metabolic processing ISO CYP2C8 protein results in increased metabolism of Dapsone CTD PMID:17286541 NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions ISO CYP2C19 protein results in increased metabolism of and results in increased susceptibility to Dapsone CTD PMID:19998329 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 affects metabolic processing
decreases activity
multiple interactions
ISO CYP2C9 protein affects the metabolism of Dapsone
Dapsone results in decreased activity of CYP2C9 protein
Dapsone promotes the reaction [CYP2C9 protein polymorphism results in decreased methylation of Naproxen]; Dapsone promotes the reaction [CYP2C9 protein polymorphism results in increased hydroxylation of Flurbiprofen]; Dapsone promotes the reaction [CYP2C9 protein results in decreased methylation of Naproxen]; Dapsone promotes the reaction [CYP2C9 protein results in increased hydroxylation of Flurbiprofen]
CTD PMID:11124226 PMID:12920490 PMID:15130760 NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 multiple interactions ISO CYP2D6 protein results in increased metabolism of and results in increased susceptibility to Dapsone CTD PMID:19998329 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Edn1 endothelin 1 multiple interactions EXP Dapsone inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA] CTD PMID:21765237 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Elk4 ELK4, member of ETS oncogene family multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of ELK4 mRNA] CTD PMID:21440447 NCBI chr 1:131,935,129...131,954,186
Ensembl chr 1:131,935,345...131,960,350
JBrowse link
G Fkbp5 FK506 binding protein 5 multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of FKBP5 mRNA] CTD PMID:21440447 NCBI chr17:28,617,727...28,705,123
Ensembl chr17:28,618,068...28,736,501
JBrowse link
G G6pdx glucose-6-phosphate dehydrogenase X-linked increases response to substance ISO G6PD protein mutant form results in increased susceptibility to Dapsone CTD PMID:7752092 NCBI chr  X:73,453,089...73,472,486
Ensembl chr  X:73,453,089...73,472,800
JBrowse link
G Greb1 gene regulated by estrogen in breast cancer protein multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of GREB1 mRNA] CTD PMID:21440447 NCBI chr12:16,720,616...16,851,395
Ensembl chr12:16,720,616...16,850,887
JBrowse link
G Gsr glutathione reductase multiple interactions EXP Dapsone inhibits the reaction [Paraquat results in decreased expression of GSR protein]; Dapsone inhibits the reaction [Paraquat results in increased expression of GSR mRNA] CTD PMID:21765237 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 multiple interactions EXP Dapsone inhibits the reaction [Paraquat results in decreased expression of GSTP1 protein] CTD PMID:21765237 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA CTD PMID:29594315 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igf1r insulin-like growth factor I receptor multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of IGF1R mRNA] CTD PMID:21440447 NCBI chr 7:67,601,486...67,883,416
Ensembl chr 7:67,602,575...67,883,416
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Dapsone results in decreased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Dapsone co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Maf MAF bZIP transcription factor multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of MAF mRNA] CTD PMID:21440447 NCBI chr 8:116,429,992...116,433,633
Ensembl chr 8:116,409,681...116,434,533
JBrowse link
G Mak male germ cell-associated kinase multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of MAK mRNA] CTD PMID:21440447 NCBI chr13:41,178,483...41,233,182
Ensembl chr13:41,178,484...41,233,182
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 multiple interactions ISO Dapsone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:21436242 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 multiple interactions ISO Dapsone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:21436242 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions EXP Dapsone inhibits the reaction [Paraquat results in increased expression of MMP9 protein] CTD PMID:21765237 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Nat2 N-acetyltransferase 2 (arylamine N-acetyltransferase) increases acetylation ISO NAT2 protein results in increased acetylation of Dapsone CTD PMID:14528063 NCBI chr 8:67,947,527...67,955,296
Ensembl chr 8:67,947,510...67,955,236
JBrowse link
G Nkx3-1 NK3 homeobox 1 multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of NKX3-1 mRNA] CTD PMID:21440447 NCBI chr14:69,428,141...69,432,107
Ensembl chr14:69,428,087...69,432,111
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions ISO
EXP
Dapsone inhibits the reaction [Paraquat results in increased expression of NOX4 mRNA] CTD PMID:20164675 PMID:21765237 NCBI chr 7:86,893,638...87,047,918
Ensembl chr 7:86,895,304...87,047,918
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of NR4A1 mRNA] CTD PMID:21440447 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Per1 period circadian clock 1 multiple interactions ISO Dapsone analog inhibits the reaction [Metribolone results in increased expression of PER1 mRNA] CTD PMID:21440447 NCBI chr11:68,985,934...69,000,791
Ensembl chr11:68,986,043...69,000,786
JBrowse link
G Plcb2 phospholipase C, beta 2 multiple interactions ISO Dapsone inhibits the reaction [Paraquat results in increased phosphorylation of PLCB2 protein] CTD PMID:20164675 NCBI chr 2:118,535,484...118,559,140
Ensembl chr 2:118,537,998...118,558,919
JBrowse link
G Prkd1 protein kinase D1 multiple interactions EXP Dapsone inhibits the reaction [Paraquat results in increased phosphorylation of PRKD1 protein] CTD PMID:21765237 NCBI chr12:50,388,009...50,696,075
Ensembl chr12:50,388,014...50,695,881
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 decreases activity ISO Dapsone analog results in decreased activity of PRMT1 protein; Dapsone results in decreased activity of PRMT1 protein CTD PMID:21440447 NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions ISO Dapsone inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of RELA protein] CTD PMID:21436242 NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Slc4a2 solute carrier family 4 (anion exchanger), member 2 decreases expression ISO Dapsone metabolite results in decreased expression of SLC4A2 protein CTD PMID:15863252 NCBI chr 5:24,628,834...24,645,945
Ensembl chr 5:24,628,835...24,645,948
JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial multiple interactions ISO
EXP
[SOD2 co-treated with CYP3A4] affects the susceptibility to Dapsone
Dapsone inhibits the reaction [Paraquat results in decreased expression of SOD2 protein]
CTD PMID:19501153 PMID:21765237 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP Dapsone inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA] CTD PMID:21765237 NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
ethionamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Ethionamide results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Ethionamide results in increased expression of CCL2 mRNA; Ethionamide results in increased expression of CCL2 protein CTD PMID:25051504 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 affects expression ISO Ethionamide affects the expression of CCL5 protein CTD PMID:25051504 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO Ethionamide results in decreased expression of CXCL10 protein CTD PMID:25051504 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Fmo2 flavin containing monooxygenase 2 increases oxidation ISO FMO2 protein results in increased oxidation of Ethionamide CTD PMID:26062974 NCBI chr 1:162,701,886...162,726,327
Ensembl chr 1:162,701,886...162,726,295
JBrowse link
G Gclm glutamate-cysteine ligase, modifier subunit multiple interactions ISO Ethionamide inhibits the reaction [arsenic trioxide results in increased expression of GCLM mRNA] CTD PMID:26708503 NCBI chr 3:122,039,206...122,060,864
Ensembl chr 3:122,039,206...122,064,381
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions ISO Ethionamide inhibits the reaction [arsenic trioxide results in increased expression of HMOX1 mRNA] CTD PMID:26708503 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Il10 interleukin 10 decreases expression ISO Ethionamide results in decreased expression of IL10 protein CTD PMID:25051504 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12b interleukin 12b increases expression ISO Ethionamide results in increased expression of IL12B protein CTD PMID:25051504 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Ethionamide results in increased expression of IL1A protein CTD PMID:25051504 NCBI chr 2:129,141,530...129,151,892
Ensembl chr 2:129,141,530...129,151,892
JBrowse link
G Il1b interleukin 1 beta increases expression
affects expression
ISO Ethionamide results in increased expression of IL1B mRNA
Ethionamide affects the expression of IL1B protein
CTD PMID:25051504 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 decreases expression ISO Ethionamide results in decreased expression of IL6 protein CTD PMID:25051504 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Keap1 kelch-like ECH-associated protein 1 multiple interactions ISO KEAP1 mRNA inhibits the reaction [Ethionamide results in increased susceptibility to arsenic trioxide] CTD PMID:26708503 NCBI chr 9:21,141,026...21,150,628
Ensembl chr 9:21,141,026...21,150,657
JBrowse link
G Lep leptin decreases expression ISO Ethionamide results in decreased expression of LEP protein CTD PMID:25051504 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions ISO NFE2L2 mRNA promotes the reaction [Ethionamide results in increased susceptibility to arsenic trioxide] CTD PMID:26708503 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Srxn1 sulfiredoxin 1 homolog (S. cerevisiae) multiple interactions ISO Ethionamide inhibits the reaction [arsenic trioxide results in increased expression of SRXN1 mRNA] CTD PMID:26708503 NCBI chr 2:151,946,738...151,953,296
Ensembl chr 2:151,947,436...151,953,296
JBrowse link
G Tnf tumor necrosis factor increases expression ISO Ethionamide results in increased expression of TNF protein CTD PMID:25051504 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Ethionamide results in increased expression of VEGFA protein CTD PMID:25051504 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
pomalidomide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Brd4 bromodomain containing 4 multiple interactions ISO pomalidomide inhibits the reaction [ARV-825 results in increased degradation of BRD4 protein] CTD PMID:26051217 NCBI chr17:32,415,246...32,503,717
Ensembl chr17:32,415,248...32,503,696
JBrowse link
G Casp3 caspase 3 multiple interactions ISO [afuresertib co-treated with pomalidomide co-treated with Dexamethasone] results in increased cleavage of CASP3 protein CTD PMID:29928335 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [afuresertib co-treated with pomalidomide co-treated with Dexamethasone] results in increased cleavage of CASP8 protein CTD PMID:29928335 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases secretion ISO pomalidomide results in increased secretion of CCL2 protein CTD PMID:15292067 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha increases expression ISO pomalidomide results in increased expression of CEBPA mRNA CTD PMID:15292067 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO pomalidomide results in increased expression of CEBPD mRNA CTD PMID:15292067 NCBI chr16:15,705,150...15,707,409
Ensembl chr16:15,705,150...15,708,895
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon increases expression ISO pomalidomide results in increased expression of CEBPE mRNA CTD PMID:15292067 NCBI chr14:54,947,823...54,949,604
Ensembl chr14:54,947,817...54,949,631
JBrowse link
G Crbn cereblon multiple interactions
affects binding
increases response to substance
ISO [pomalidomide co-treated with Dexamethasone co-treated with afuresertib] results in increased expression of CRBN protein; [pomalidomide co-treated with Dexamethasone] results in increased expression of CRBN protein; pomalidomide inhibits the reaction [CRBN protein binds to and results in increased ubiquitination of and results in increased degradation of MEIS2 protein]
pomalidomide binds to [SALL4 protein binds to CRBN protein]
CRBN results in increased susceptibility to pomalidomide
CTD PMID:25043012 PMID:26186254 PMID:29928335 PMID:30067223 NCBI chr 6:106,755,205...106,777,060
Ensembl chr 6:106,757,162...106,777,038
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) decreases secretion ISO pomalidomide results in decreased secretion of CSF2 protein CTD PMID:15292067 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) increases secretion ISO pomalidomide results in increased secretion of CSF3 protein CTD PMID:15292067 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 increases oxidation ISO CYP2C19 protein results in increased oxidation of pomalidomide CTD PMID:24350712 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 increases oxidation ISO CYP2J2 protein results in increased oxidation of pomalidomide CTD PMID:24350712 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Dtwd1 DTW domain containing 1 multiple interactions ISO pomalidomide results in increased degradation of and results in decreased expression of DTWD1 protein CTD PMID:30067223 NCBI chr 2:125,993,981...126,007,197
Ensembl chr 2:125,994,061...126,007,199
JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions ISO [pomalidomide co-treated with Dexamethasone] results in decreased phosphorylation of EIF4EBP1 protein; afuresertib promotes the reaction [[pomalidomide co-treated with Dexamethasone] results in decreased phosphorylation of EIF4EBP1 protein] CTD PMID:29928335 NCBI chr 8:27,750,355...27,765,684
Ensembl chr 8:27,750,357...27,766,702
JBrowse link
G Fam83f family with sequence similarity 83, member F multiple interactions ISO pomalidomide results in increased degradation of and results in decreased expression of FAM83F protein CTD PMID:30067223 NCBI chr15:80,555,829...80,584,626
Ensembl chr15:80,556,048...80,584,626
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 decreases expression ISO pomalidomide results in decreased expression of FGFR1 mRNA CTD PMID:30834740 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 affects expression ISO pomalidomide affects the expression of FGFR3 mRNA CTD PMID:30834740 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
JBrowse link
G Foxo1 forkhead box O1 multiple interactions ISO [pomalidomide co-treated with Dexamethasone] affects the phosphorylation of FOXO1 protein; afuresertib affects the reaction [[pomalidomide co-treated with Dexamethasone] affects the phosphorylation of FOXO1 protein] CTD PMID:29928335 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642
JBrowse link
G Gata1 GATA binding protein 1 decreases expression ISO pomalidomide results in decreased expression of GATA1 mRNA; pomalidomide results in decreased expression of GATA1 protein CTD PMID:15292067 NCBI chr  X:7,825,504...7,842,844
Ensembl chr  X:7,825,499...7,844,310
JBrowse link
G Gata2 GATA binding protein 2 decreases expression ISO pomalidomide results in decreased expression of GATA2 mRNA CTD PMID:15292067 NCBI chr 6:88,170,873...88,184,014
Ensembl chr 6:88,170,873...88,184,014
JBrowse link
G Gfi1 growth factor independent 1 transcription repressor increases expression ISO pomalidomide results in increased expression of GFI1 mRNA CTD PMID:15292067 NCBI chr 5:107,864,521...107,873,671
Ensembl chr 5:107,864,523...107,873,902
JBrowse link
G Gfi1b growth factor independent 1B decreases expression ISO pomalidomide results in decreased expression of GFI1B mRNA CTD PMID:15292067 NCBI chr 2:28,499,462...28,511,994
Ensembl chr 2:28,499,462...28,511,994
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression ISO pomalidomide results in increased expression of ID1 mRNA CTD PMID:15292067 NCBI chr 2:152,578,171...152,579,330
Ensembl chr 2:152,578,171...152,579,330
JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression ISO pomalidomide results in increased expression of ID2 mRNA CTD PMID:15292067 NCBI chr12:25,143,798...25,146,091
Ensembl chr12:25,143,798...25,147,139
JBrowse link
G Ikzf1 IKAROS family zinc finger 1 multiple interactions ISO [pomalidomide co-treated with Dexamethasone] results in decreased expression of IKZF1 protein; afuresertib promotes the reaction [[pomalidomide co-treated with Dexamethasone] results in decreased expression of IKZF1 protein] CTD PMID:29928335 NCBI chr11:11,634,970...11,722,930
Ensembl chr11:11,634,980...11,722,926
JBrowse link
G Ikzf3 IKAROS family zinc finger 3 multiple interactions ISO [pomalidomide co-treated with Dexamethasone] results in decreased expression of IKZF3 protein; afuresertib promotes the reaction [[pomalidomide co-treated with Dexamethasone] results in decreased expression of IKZF3 protein] CTD PMID:29928335 NCBI chr11:98,355,436...98,437,157
Ensembl chr11:98,355,728...98,436,857
JBrowse link
G Il10 interleukin 10 increases secretion ISO pomalidomide results in increased secretion of IL10 protein CTD PMID:15292067 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il13 interleukin 13 decreases secretion ISO pomalidomide results in decreased secretion of IL13 protein CTD PMID:15292067 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il2 interleukin 2 multiple interactions ISO Go 6976 inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 mRNA]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]; pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased secretion of IL2 protein]; rottlerin inhibits the reaction [pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2 protein]] CTD PMID:16241859 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il5 interleukin 5 decreases secretion ISO pomalidomide results in decreased secretion of IL5 protein CTD PMID:15292067 NCBI chr11:53,611,621...53,615,930
Ensembl chr11:53,611,621...53,615,933
JBrowse link
G Irf4 interferon regulatory factor 4 multiple interactions ISO [pomalidomide co-treated with Dexamethasone co-treated with afuresertib] results in decreased expression of IRF4 protein; [pomalidomide co-treated with Dexamethasone] results in decreased expression of IRF4 protein CTD PMID:29928335 NCBI chr13:30,933,191...30,950,965
Ensembl chr13:30,933,209...30,950,959
JBrowse link
G Jund jun D proto-oncogene decreases expression ISO pomalidomide results in decreased expression of JUND mRNA CTD PMID:15292067 NCBI chr 8:71,150,389...71,153,265
Ensembl chr 8:71,151,599...71,153,265
JBrowse link
G Klf1 Kruppel-like transcription factor 1 (erythroid) decreases expression ISO pomalidomide results in decreased expression of KLF1 mRNA CTD PMID:15292067 NCBI chr 8:85,628,611...85,631,920
Ensembl chr 8:85,628,557...85,631,924
JBrowse link
G Lmo2 LIM domain only 2 decreases expression ISO pomalidomide results in decreased expression of LMO2 mRNA CTD PMID:15292067 NCBI chr 2:103,788,309...103,812,223
Ensembl chr 2:103,788,331...103,812,223
JBrowse link
G Meis2 Meis homeobox 2 multiple interactions ISO pomalidomide inhibits the reaction [CRBN protein binds to and results in increased ubiquitination of and results in increased degradation of MEIS2 protein] CTD PMID:25043012 NCBI chr 2:115,691,745...115,897,925
Ensembl chr 2:115,693,545...115,896,320
JBrowse link
G Nfe2 nuclear factor, erythroid derived 2 decreases expression ISO pomalidomide results in decreased expression of NFE2 mRNA CTD PMID:15292067 NCBI chr15:103,156,640...103,166,809
Ensembl chr15:103,156,639...103,166,830
JBrowse link
G Prkcq protein kinase C, theta multiple interactions ISO pomalidomide promotes the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased activity of PRKCQ protein] CTD PMID:16241859 NCBI chr 2:11,176,922...11,306,033
Ensembl chr 2:11,176,919...11,306,033
JBrowse link
G Rab28 RAB28, member RAS oncogene family multiple interactions ISO pomalidomide results in increased degradation of and results in decreased expression of RAB28 protein CTD PMID:30067223 NCBI chr 5:41,782,316...41,865,535
Ensembl chr 5:41,782,319...41,865,500
JBrowse link
G Sall4 spalt like transcription factor 4 multiple interactions
affects binding
ISO pomalidomide results in increased degradation of and results in decreased expression of SALL4 protein
pomalidomide binds to [SALL4 protein binds to CRBN protein]
CTD PMID:30067223 NCBI chr 2:168,590,252...168,609,121
Ensembl chr 2:168,590,252...168,609,863
JBrowse link
G Spi1 Spi-1 proto-oncogene increases expression
decreases expression
ISO pomalidomide results in increased expression of SPI1 mRNA
pomalidomide results in decreased expression of SPI1 protein
CTD PMID:15292067 PMID:16373662 NCBI chr 2:90,912,750...90,946,104
Ensembl chr 2:90,912,735...90,946,101
JBrowse link
G Wiz widely-interspaced zinc finger motifs multiple interactions ISO pomalidomide results in increased degradation of and results in decreased expression of WIZ protein CTD PMID:30067223 NCBI chr17:32,573,021...32,608,463
Ensembl chr17:32,573,029...32,608,413
JBrowse link
G Zbtb39 zinc finger and BTB domain containing 39 multiple interactions ISO pomalidomide results in increased degradation of and results in decreased expression of ZBTB39 protein CTD PMID:30067223 NCBI chr10:127,575,399...127,583,218
Ensembl chr10:127,575,407...127,583,218
JBrowse link
G Zfp653 zinc finger protein 653 multiple interactions ISO pomalidomide results in increased degradation of and results in decreased expression of ZNF653 protein CTD PMID:30067223 NCBI chr 9:21,966,705...21,982,707
Ensembl chr 9:21,966,707...21,982,672
JBrowse link
G Zfp91 zinc finger protein 91 multiple interactions ISO pomalidomide results in increased degradation of and results in decreased expression of ZFP91 protein CTD PMID:30067223 NCBI chr19:12,744,303...12,773,487
Ensembl chr19:12,744,384...12,773,490
JBrowse link
rifampicin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 1700011L22Rik RIKEN cDNA 1700011L22 gene decreases expression ISO Rifampin results in decreased expression of C4ORF51 mRNA CTD PMID:24552687 NCBI chr 8:79,937,059...79,975,212
Ensembl chr 8:79,937,060...79,975,199
JBrowse link
G 4921517D22Rik RIKEN cDNA 4921517D22 gene decreases expression ISO Rifampin results in decreased expression of C9ORF153 mRNA CTD PMID:24552687 NCBI chr13:59,835,216...59,841,917
Ensembl chr13:59,835,216...59,841,922
JBrowse link
G Aadac arylacetamide deacetylase multiple interactions
increases hydrolysis
decreases acetylation
ISO AADAC mRNA affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Isoflurophate inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Phenylmethylsulfonyl Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]; Sodium Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of Rifampin]
AADAC protein results in increased hydrolysis of Rifampin
CTD PMID:21856291 PMID:22207054 NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581
JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 decreases expression
increases expression
ISO Rifampin results in decreased expression of ABCA1 mRNA; Rifampin results in decreased expression of ABCA1 protein
Rifampin results in increased expression of ABCA1 mRNA; Rifampin results in increased expression of ABCA1 protein
CTD PMID:15883047 PMID:17088262 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abca2 ATP-binding cassette, sub-family A member 2 increases expression ISO Rifampin results in increased expression of ABCA2 mRNA CTD PMID:27199754 NCBI chr 2:25,318,611...25,338,556
Ensembl chr 2:25,318,715...25,338,552
JBrowse link
G Abca8b ATP-binding cassette, sub-family A member 8b decreases expression ISO Rifampin results in decreased expression of ABCA8 mRNA CTD PMID:27199754 NCBI chr11:109,823,016...109,886,642
Ensembl chr11:109,823,016...109,886,671
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases expression
multiple interactions
decreases activity
ISO
EXP
Rifampin results in decreased expression of ABCB11 mRNA
Rifampin results in decreased expression of ABCB11 protein
[Rifampin co-treated with Isoniazid] results in decreased expression of ABCB11 protein
tanshinone inhibits the reaction [Rifampin results in decreased expression of ABCB11 mRNA]; tanshinone inhibits the reaction [Rifampin results in decreased expression of ABCB11 protein]
Rifampin results in decreased activity of ABCB11 protein
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of ABCB11 protein; Rifampin inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Rifampin results in decreased expression of ABCB11 mRNA; Rifampin results in decreased expression of ABCB11 protein
CTD PMID:12135489 PMID:16837569 PMID:20829430 PMID:24014644 PMID:25886055 More... NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A affects activity
increases expression
multiple interactions
decreases activity
ISO Rifampin affects the activity of ABCB1 protein
Rifampin results in increased expression of ABCB1 mRNA; Rifampin results in increased expression of ABCB1 protein
[Rifampin metabolite results in decreased activity of ABCB1A protein] which results in decreased abundance of Adenosine Triphosphate
[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein; [Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein; Camptothecin inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of ABCB1 mRNA]; Resveratrol inhibits the reaction [Rifampin results in increased expression of ABCB1 protein]; Rifampin promotes the reaction [ABCB1 protein results in increased transport of Digoxin]; Rifampin promotes the reaction [NR1I2 protein binds to ABCB1 promoter]
CTD PMID:8632764 PMID:11744607 PMID:14722322 PMID:15276086 PMID:15290871 More... NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb4 ATP-binding cassette, sub-family B member 4 increases expression ISO Rifampin results in increased expression of ABCB4 mRNA CTD PMID:27199754 NCBI chr 5:8,943,614...9,009,226
Ensembl chr 5:8,943,717...9,009,231
JBrowse link
G Abcb6 ATP-binding cassette, sub-family B member 6 increases expression ISO Rifampin results in increased expression of ABCB6 mRNA CTD PMID:27199754 NCBI chr 1:75,148,284...75,157,066
Ensembl chr 1:75,148,361...75,157,036
JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 increases expression ISO Rifampin results in increased expression of ABCC1 mRNA CTD PMID:17191263 PMID:35972551 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601
JBrowse link
G Abcc10 ATP-binding cassette, sub-family C member 10 increases expression ISO Rifampin results in increased expression of ABCC10 mRNA CTD PMID:27199754 NCBI chr17:46,614,146...46,638,954
Ensembl chr17:46,614,147...46,639,278
JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 affects export
multiple interactions
increases expression
ISO ABCC2 protein affects the export of Rifampin
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of ABCC2 protein
Rifampin results in increased expression of ABCC2; Rifampin results in increased expression of ABCC2 mRNA; Rifampin results in increased expression of ABCC2 protein
[Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein
CTD PMID:11836020 PMID:12206135 PMID:15652233 PMID:16837569 PMID:16952291 More... NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179
JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 multiple interactions
increases expression
increases activity
ISO [Rifampin co-treated with ABCC2 gene mutant form] results in increased expression of ABCC3 protein; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; Rifampin inhibits the reaction [decitabine results in increased expression of ABCC3 mRNA]
Rifampin results in increased expression of ABCC3 mRNA
Rifampin results in increased activity of ABCC3 protein
CTD PMID:14570758 PMID:16837569 PMID:16952291 PMID:19041851 PMID:20832446 More... NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823
JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 increases expression ISO Rifampin results in increased expression of ABCC5 mRNA CTD PMID:19041851 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144
JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 increases expression ISO Rifampin results in increased expression of ABCC6 mRNA CTD PMID:27199754 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726
JBrowse link
G Abcf1 ATP-binding cassette, sub-family F member 1 increases expression ISO Rifampin results in increased expression of ABCF1 mRNA CTD PMID:27199754 NCBI chr17:36,267,711...36,280,642
Ensembl chr17:36,267,711...36,280,653
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Rifampin results in increased expression of ABCG1 mRNA; Rifampin results in increased expression of ABCG1 protein CTD PMID:12040753 PMID:17088262 NCBI chr17:31,276,668...31,336,958
Ensembl chr17:31,276,649...31,336,962
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases expression ISO Rifampin results in increased expression of ABCG2 mRNA CTD PMID:16837569 PMID:27199754 PMID:35972551 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661
JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression ISO Rifampin results in increased expression of ABCG8 mRNA CTD PMID:27199754 NCBI chr17:84,983,730...85,007,761
Ensembl chr17:84,983,730...85,007,761
JBrowse link
G Abi3 ABI family member 3 decreases expression ISO Rifampin results in decreased expression of ABI3 mRNA CTD PMID:24552687 NCBI chr11:95,720,898...95,733,302
Ensembl chr11:95,720,900...95,733,302
JBrowse link
G Acaca acetyl-Coenzyme A carboxylase alpha increases expression EXP Rifampin results in increased expression of ACACA mRNA CTD PMID:27806127 NCBI chr11:84,020,461...84,292,477
Ensembl chr11:84,020,498...84,292,477
JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Rifampin results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416
JBrowse link
G Acsl4 acyl-CoA synthetase long-chain family member 4 multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of ACSL4 protein CTD PMID:36878459 NCBI chr  X:141,100,989...141,173,792
Ensembl chr  X:141,100,989...141,173,531
JBrowse link
G Actr10 ARP10 actin-related protein 10 increases expression ISO Rifampin results in increased expression of ACTR10 mRNA CTD PMID:24552687 NCBI chr12:70,984,631...71,011,492
Ensembl chr12:70,984,631...71,011,492
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) increases expression ISO Rifampin results in increased expression of ADH1C mRNA CTD PMID:12040753 NCBI chr 3:137,983,346...137,996,459
Ensembl chr 3:137,966,752...137,996,459
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions EXP [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of ADIPOQ mRNA CTD PMID:33412187 NCBI chr16:22,965,286...22,976,718
Ensembl chr16:22,965,286...22,976,778
JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Rifampin results in decreased expression of ADORA2A mRNA CTD PMID:24552687 NCBI chr10:75,152,711...75,170,626
Ensembl chr10:75,152,711...75,170,618
JBrowse link
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 decreases expression ISO Rifampin results in decreased expression of AGAP2 mRNA CTD PMID:24552687 NCBI chr10:126,911,154...126,929,039
Ensembl chr10:126,911,153...126,929,038
JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
increases expression
ISO [Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in decreased expression of AHR mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of AHR protein; NR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]
Rifampin results in increased expression of AHR mRNA; Rifampin results in increased expression of AHR protein
CTD PMID:22733800 PMID:28428138 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037
JBrowse link
G Akr1b10 aldo-keto reductase family 1, member B10 multiple interactions
increases expression
ISO pazopanib inhibits the reaction [Rifampin results in increased expression of AKR1B10 mRNA]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of AKR1B10 mRNA] CTD PMID:29356861 NCBI chr 6:34,361,182...34,373,884
Ensembl chr 6:34,361,153...34,373,885
JBrowse link
G Alas1 aminolevulinic acid synthase 1 increases expression ISO Rifampin results in increased expression of ALAS1 mRNA CTD PMID:24259679 PMID:24552687 NCBI chr 9:106,110,654...106,125,153
Ensembl chr 9:106,110,654...106,125,853
JBrowse link
G Alpl alkaline phosphatase, liver/bone/kidney multiple interactions
increases activity
EXP [Rifampin co-treated with Isoniazid] results in increased activity of ALPL protein
Rifampin results in increased activity of ALPL protein
CTD PMID:25886055 NCBI chr 4:137,469,042...137,523,695
Ensembl chr 4:137,469,044...137,523,695
JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO Rifampin results in decreased expression of ANGPTL3 mRNA CTD PMID:32535746 NCBI chr 4:98,919,191...98,926,429
Ensembl chr 4:98,919,191...98,934,348
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA CTD PMID:21127053 NCBI chr17:33,993,874...34,000,549
Ensembl chr17:33,992,724...34,000,804
JBrowse link
G Ankrd40 ankyrin repeat domain 40 increases expression ISO Rifampin results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:94,218,827...94,232,673
Ensembl chr11:94,218,827...94,232,667
JBrowse link
G Ankrd65 ankyrin repeat domain 65 decreases expression ISO Rifampin results in decreased expression of ANKRD65 mRNA CTD PMID:24552687 NCBI chr 4:155,875,432...155,884,132
Ensembl chr 4:155,874,896...155,877,659
JBrowse link
G Anks1b ankyrin repeat and sterile alpha motif domain containing 1B decreases expression ISO Rifampin results in decreased expression of ANKS1B mRNA CTD PMID:24552687 NCBI chr10:89,707,238...90,809,162
Ensembl chr10:89,709,371...90,809,162
JBrowse link
G Anxa5 annexin A5 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA CTD PMID:21224054 NCBI chr 3:36,503,072...36,530,036
Ensembl chr 3:36,503,072...36,530,043
JBrowse link
G Apob apolipoprotein B decreases expression
multiple interactions
affects secretion
ISO Rifampin results in decreased expression of APOB mRNA
ursodoxicoltaurine inhibits the reaction [Rifampin results in decreased expression of APOB mRNA]
Rifampin affects the secretion of APOB protein
CTD PMID:32535746 NCBI chr12:8,027,629...8,066,839
Ensembl chr12:8,027,648...8,066,835
JBrowse link
G Apoc3 apolipoprotein C-III decreases secretion
decreases expression
ISO Rifampin results in decreased secretion of APOC3 protein
Rifampin results in decreased expression of APOC3 mRNA
CTD PMID:32535746 NCBI chr 9:46,144,348...46,146,934
Ensembl chr 9:46,144,231...46,146,934
JBrowse link
G Aqp3 aquaporin 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA CTD PMID:21127053 NCBI chr 4:41,092,724...41,098,183
Ensembl chr 4:41,092,722...41,098,183
JBrowse link
G Aqp4 aquaporin 4 decreases expression ISO Rifampin results in decreased expression of AQP4 mRNA CTD PMID:24552687 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039
JBrowse link
G Arsj arylsulfatase J decreases expression ISO Rifampin results in decreased expression of ARSJ mRNA CTD PMID:24552687 NCBI chr 3:126,157,566...126,234,025
Ensembl chr 3:126,157,333...126,234,024
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions EXP [Rifampin co-treated with Cobicistat] results in increased expression of ATF3 mRNA CTD PMID:33629115 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression
ISO ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
Rifampin results in increased expression of ATF4 mRNA; Rifampin results in increased expression of ATF4 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of ATF4 protein]
CTD PMID:24638036 PMID:27470132 NCBI chr15:80,139,385...80,141,746
Ensembl chr15:80,139,385...80,141,742
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Rifampin results in increased expression of ATF6 mRNA CTD PMID:32535746 NCBI chr 1:170,532,026...170,696,414
Ensembl chr 1:170,532,243...170,695,340
JBrowse link
G Atm ataxia telangiectasia mutated multiple interactions
decreases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein
Rifampin results in decreased expression of ATM mRNA
CTD PMID:21224054 PMID:24552687 NCBI chr 9:53,348,422...53,448,125
Ensembl chr 9:53,350,449...53,448,040
JBrowse link
G Atp6v0a1 ATPase, H+ transporting, lysosomal V0 subunit A1 increases expression
multiple interactions
ISO Rifampin results in increased expression of ATP6V0A1 protein
[Rotenone co-treated with Rifampin] results in increased expression of ATP6V0A1 protein; Rifampin inhibits the reaction [Rotenone results in decreased expression of ATP6V0A1 mRNA]; Rotenone inhibits the reaction [Rifampin results in increased expression of ATP6V0A1 protein]
CTD PMID:31648047 NCBI chr11:100,899,262...100,954,545
Ensembl chr11:100,900,278...100,954,545
JBrowse link
G Atp6v0d1 ATPase, H+ transporting, lysosomal V0 subunit D1 multiple interactions ISO ATP6V0D1 protein affects the reaction [Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]] CTD PMID:31648047 NCBI chr 8:106,251,093...106,292,696
Ensembl chr 8:106,251,097...106,292,679
JBrowse link
G Atrx ATRX, chromatin remodeler increases expression ISO Rifampin results in increased expression of ATRX mRNA CTD PMID:24552687 NCBI chr  X:104,841,221...104,972,978
Ensembl chr  X:104,841,221...104,973,009
JBrowse link
G Bax BCL2-associated X protein multiple interactions
decreases expression
EXP
ISO
[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of BAX mRNA; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased expression of BAX protein]
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein
Rifampin results in decreased expression of BAX protein
CTD PMID:11958592 PMID:12645856 PMID:21224054 PMID:21419764 PMID:31629065 More... NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 increases expression
multiple interactions
ISO
EXP
Rifampin results in increased expression of BCL2 protein
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein
[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in decreased expression of BCL2 protein]
CTD PMID:11958592 PMID:21419764 PMID:31629065 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 increases expression
multiple interactions
ISO
EXP
Rifampin results in increased expression of BCL2L1 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA
CTD PMID:11958592 PMID:12645856 PMID:21224054 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA CTD PMID:21127053 NCBI chr 6:108,637,590...108,643,886
Ensembl chr 6:108,637,590...108,643,886
JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA CTD PMID:21127053 NCBI chr14:46,620,982...46,628,126
Ensembl chr14:46,620,977...46,628,126
JBrowse link
G Car1 carbonic anhydrase 1 decreases expression ISO Rifampin results in decreased expression of CA1 mRNA CTD PMID:24552687 NCBI chr 3:14,831,274...14,873,425
Ensembl chr 3:14,831,276...14,873,428
JBrowse link
G Casp1 caspase 1 multiple interactions EXP Rifampin inhibits the reaction [Rotenone results in increased cleavage of CASP1 protein] CTD PMID:26086368 NCBI chr 9:5,298,517...5,307,281
Ensembl chr 9:5,298,508...5,307,290
JBrowse link
G Casp3 caspase 3 multiple interactions ISO
EXP
Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of CASP3 protein]; Rifampin inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Rifampin inhibits the reaction [Staurosporine results in increased cleavage of CASP3 protein]; Rifampin promotes the reaction [Galactosamine results in increased activity of CASP3 protein]
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of CASP3
[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein; HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein]; Ursodeoxycholic Acid inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein]
CTD PMID:11958592 PMID:12645856 PMID:17936189 PMID:21419764 PMID:23764483 More... NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein] CTD PMID:11958592 PMID:12645856 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Cat catalase multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of CAT protein CTD PMID:36878459 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbr3 carbonyl reductase 3 multiple interactions EXP [Rifampin co-treated with Cobicistat] results in increased expression of CBR3 mRNA CTD PMID:33629115 NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Rifampin results in decreased expression of CCL2 mRNA CTD PMID:25051504 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 decreases expression ISO Rifampin results in decreased expression of CCL5 protein CTD PMID:25051504 NCBI chr11:83,416,604...83,421,344
Ensembl chr11:83,416,604...83,421,344
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA CTD PMID:21127053 NCBI chr 3:145,352,726...145,355,740
Ensembl chr 3:145,352,731...145,355,736
JBrowse link
G Ccnd1 cyclin D1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA CTD PMID:21224054 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccng1 cyclin G1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA CTD PMID:21224054 NCBI chr11:40,639,379...40,646,044
Ensembl chr11:40,639,379...40,646,138
JBrowse link
G Ccr6 C-C motif chemokine receptor 6 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA CTD PMID:21127053 NCBI chr17:8,454,875...8,477,353
Ensembl chr17:8,454,875...8,475,973
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA CTD PMID:21127053 NCBI chr11:99,035,025...99,045,903
Ensembl chr11:99,035,022...99,045,903
JBrowse link
G Cd36 CD36 molecule increases expression EXP Rifampin results in increased expression of CD36 mRNA CTD PMID:27806127 NCBI chr 5:17,986,680...18,093,828
Ensembl chr 5:17,986,688...18,093,799
JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein CTD PMID:21224054 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701
JBrowse link
G Cdkn2b cyclin dependent kinase inhibitor 2B multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA CTD PMID:21127053 NCBI chr 4:89,224,526...89,229,269
Ensembl chr 4:89,224,536...89,229,276
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions EXP [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of CEBPA mRNA; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPA mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPA protein] CTD PMID:33412187 NCBI chr 7:34,818,718...34,821,353
Ensembl chr 7:34,818,718...34,821,353
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of CEBPB mRNA; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPB mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPB protein] CTD PMID:33412187 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions EXP [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of CEBPD mRNA; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPD mRNA] CTD PMID:33412187 NCBI chr16:15,705,150...15,707,409
Ensembl chr16:15,705,150...15,708,895
JBrowse link
G Ces1d carboxylesterase 1D increases expression ISO Rifampin results in increased expression of CES1 protein CTD PMID:10640517 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466
JBrowse link
G Ces2a carboxylesterase 2A multiple interactions EXP [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CES2A mRNA CTD PMID:22467028 NCBI chr 8:105,460,635...105,468,266
Ensembl chr 8:105,460,635...105,468,266
JBrowse link
G Ces2h carboxylesterase 2H increases expression
multiple interactions
ISO Rifampin results in increased expression of CES2 mRNA; Rifampin results in increased expression of CES2 protein
Dichlororibofuranosylbenzimidazole inhibits the reaction [Rifampin results in increased expression of CES2 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]
CTD PMID:10640517 PMID:17003103 NCBI chr 8:105,727,462...105,747,042
Ensembl chr 8:105,727,485...105,747,810
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator multiple interactions
increases expression
ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]
Rifampin results in increased expression of CFLAR protein
CTD PMID:11958592 PMID:12645856 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA CTD PMID:21224054 NCBI chr 5:110,987,668...111,022,006
Ensembl chr 5:110,987,845...111,022,011
JBrowse link
G Ciz1 CDKN1A interacting zinc finger protein 1 decreases expression ISO Rifampin results in decreased expression of CIZ1 mRNA CTD PMID:24552687 NCBI chr 2:32,252,724...32,268,311
Ensembl chr 2:32,242,339...32,270,982
JBrowse link
G Clk2 CDC-like kinase 2 decreases expression ISO Rifampin results in decreased expression of CLK2 mRNA CTD PMID:24552687 NCBI chr 3:89,072,102...89,084,394
Ensembl chr 3:89,072,102...89,084,228
JBrowse link
G Cntln centlein, centrosomal protein increases expression ISO Rifampin results in increased expression of CNTLN mRNA CTD PMID:24552687 NCBI chr 4:84,800,024...85,050,160
Ensembl chr 4:84,802,546...85,050,158
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1a, liver increases expression EXP Rifampin results in increased expression of CPT1A mRNA CTD PMID:27806127 NCBI chr19:3,372,328...3,435,735
Ensembl chr19:3,372,334...3,435,733
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 decreases expression ISO Rifampin results in decreased expression of CRHR1 mRNA CTD PMID:24552687 NCBI chr11:104,021,289...104,066,349
Ensembl chr11:104,023,681...104,066,349
JBrowse link
G Crp C-reactive protein, pentraxin-related multiple interactions ISO [Floxacillin co-treated with Gentamicins co-treated with Rifampin] results in increased expression of CRP protein CTD PMID:16943303 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csnk1g1 casein kinase 1, gamma 1 decreases expression ISO Rifampin results in decreased expression of CSNK1G1 mRNA CTD PMID:24552687 NCBI chr 9:65,816,235...65,952,297
Ensembl chr 9:65,816,206...65,952,297
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression ISO Rifampin results in increased expression of CXCL1 protein CTD PMID:25051504 NCBI chr 5:91,039,104...91,040,980
Ensembl chr 5:91,039,100...91,040,974
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 multiple interactions
affects expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA
Rifampin affects the expression of CXCL10 protein
CTD PMID:21224054 PMID:25051504 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cyb5rl cytochrome b5 reductase-like increases expression ISO Rifampin results in increased expression of CYB5RL mRNA CTD PMID:24552687 NCBI chr 4:106,924,035...106,945,204
Ensembl chr 4:106,924,185...106,945,465
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases activity
increases expression
ISO Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Rifampin results in increased activity of CYP1A1 protein
Rifampin results in increased expression of CYP1A1 mRNA; Rifampin results in increased expression of CYP1A1 protein
[Methylcholanthrene co-treated with Rifampin co-treated with Phenobarbital] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased activity of CYP1A1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP1A1 protein; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A1 mRNA; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
CTD PMID:12040753 PMID:18493746 PMID:19118567 PMID:19409404 PMID:22733800 More... NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
increases expression
ISO
EXP
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1A2 mRNA; Rifampin inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
Rifampin results in increased expression of CYP1A2 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein
Rifampin results in increased expression of CYP1A2 mRNA; Rifampin results in increased expression of CYP1A2 protein
CTD PMID:15977188 PMID:17590308 PMID:18493746 PMID:25835148 PMID:29162470 More... NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP1B1 mRNA
CTD PMID:21224054 PMID:29162470 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions
increases expression
increases activity
ISO NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]; Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]
Rifampin results in increased activity of CYP24A1 protein
CTD PMID:15630458 PMID:21127053 NCBI chr 2:170,324,877...170,339,065
Ensembl chr 2:170,324,628...170,339,065
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA CTD PMID:21127053 NCBI chr19:37,686,186...37,689,984
Ensembl chr19:37,686,246...37,689,984
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions
increases expression
ISO Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]
Rifampin results in increased expression of CYP27A1 mRNA
CTD PMID:17088262 NCBI chr 1:74,752,311...74,777,056
Ensembl chr 1:74,752,733...74,777,051
JBrowse link
G Cyp2a22 cytochrome P450, family 2, subfamily a, polypeptide 22 increases expression ISO Rifampin results in increased expression of CYP2A1 mRNA CTD PMID:19118567 NCBI chr 7:26,631,564...26,638,838
Ensembl chr 7:26,631,056...26,638,809
JBrowse link
G Cyp2a4 cytochrome P450, family 2, subfamily a, polypeptide 4 increases expression EXP Rifampin results in increased expression of CYP2A4 mRNA CTD PMID:30503582 NCBI chr 7:26,006,617...26,014,513
Ensembl chr 7:26,006,594...26,014,513
JBrowse link
G Cyp2a5 cytochrome P450, family 2, subfamily a, polypeptide 5 multiple interactions
increases expression
increases activity
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2A5 mRNA
Rifampin results in increased expression of CYP2A6 mRNA; Rifampin results in increased expression of CYP2A6 protein
[Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of CYP2A6 mRNA; Rifampin promotes the reaction [NR1I2 protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [PPARGC1A protein binds to CYP2A6 promoter]
Rifampin results in increased expression of CYP2A5 mRNA
Rifampin results in increased activity of CYP2A5 protein
CTD PMID:11038160 PMID:14709624 PMID:15629111 PMID:16857725 PMID:19118567 More... NCBI chr 7:26,534,764...26,542,689
Ensembl chr 7:26,534,730...26,542,973
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 multiple interactions
increases expression
increases activity
EXP
ISO
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA
Rifampin results in increased expression of CYP2B10 mRNA
Rifampin results in increased expression of CYP2B6 mRNA; Rifampin results in increased expression of CYP2B6 protein
[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2B6 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2B6 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; Dexamethasone promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; GW 3965 inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; Rifampin results in increased expression of and results in increased activity of CYP2B6 protein
Rifampin results in increased activity of CYP2B6 protein
CTD PMID:12040753 PMID:12571232 PMID:12695351 PMID:14709624 PMID:14977870 More... NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 multiple interactions
decreases expression
EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2B9 mRNA
Rifampin results in decreased expression of CYP2B9 mRNA
CTD PMID:21224054 PMID:30503582 NCBI chr 7:25,872,775...25,910,086
Ensembl chr 7:25,872,836...25,910,086
JBrowse link
G Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 multiple interactions
increases expression
affects binding
increases activity
EXP
ISO
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein
Rifampin results in increased expression of CYP2C29 mRNA
[Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of BCL2 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein; [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in increased expression of BAX protein; Camptothecin inhibits the reaction [Rifampin results in increased expression of CYP2C8 mRNA]; pimecrolimus inhibits the reaction [Rifampin results in increased expression of CYP2C8 mRNA]; Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]
Rifampin results in increased expression of CYP2C8 mRNA; Rifampin results in increased expression of CYP2C8 protein
[Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter
Rifampin results in increased activity of CYP2C8 protein
CTD PMID:12040753 PMID:15771232 PMID:15933212 PMID:17954527 PMID:19118567 More... NCBI chr19:39,275,541...39,319,157
Ensembl chr19:39,257,849...39,319,157
JBrowse link
G Cyp2c37 cytochrome P450, family 2. subfamily c, polypeptide 37 increases expression EXP Rifampin results in increased expression of CYP2C37 mRNA CTD PMID:30503582 NCBI chr19:39,980,868...40,000,687
Ensembl chr19:39,980,868...40,000,687
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 multiple interactions
increases activity
increases expression
ISO Rifampin results in increased expression of and results in increased activity of CYP2C19 protein
Rifampin results in increased activity of CYP2C19 protein
Rifampin results in increased expression of CYP2C19 mRNA; Rifampin results in increased expression of CYP2C19 protein
CTD PMID:12584154 PMID:14709624 PMID:15629111 PMID:17954527 PMID:19118567 More... NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene decreases expression ISO Rifampin results in decreased expression of CYP2C18 mRNA; Rifampin results in decreased expression of CYP2C18 protein CTD PMID:22258563 PMID:31629065 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733
JBrowse link
G Cyp2c65 cytochrome P450, family 2, subfamily c, polypeptide 65 multiple interactions
affects response to substance
increases expression
increases activity
ISO Ketoconazole inhibits the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP2C9 mRNA]; Rifampin results in increased activity of and results in increased expression of CYP2C9 protein; Rifampin results in increased expression of and results in increased activity of CYP2C9 protein
CYP2C9 alternative form affects the susceptibility to Rifampin
Rifampin results in increased expression of CYP2C9 mRNA; Rifampin results in increased expression of CYP2C9 protein
Rifampin results in increased activity of CYP2C9 protein
CTD PMID:14600250 PMID:14709624 PMID:14722322 PMID:15629111 PMID:15802389 More... NCBI chr19:39,049,450...39,082,392
Ensembl chr19:39,049,459...39,082,388
JBrowse link
G Cyp2d22 cytochrome P450, family 2, subfamily d, polypeptide 22 increases expression
increases activity
decreases expression
ISO
EXP
Rifampin results in increased expression of CYP2D6 mRNA
Rifampin results in increased activity of CYP2D6 protein
Rifampin results in decreased expression of CYP2D22 mRNA
CTD PMID:19041851 PMID:30503582 PMID:33844597 NCBI chr15:82,254,728...82,264,461
Ensembl chr15:82,254,728...82,264,461
JBrowse link
G Cyp2d9 cytochrome P450, family 2, subfamily d, polypeptide 9 decreases expression EXP Rifampin results in decreased expression of CYP2D9 mRNA CTD PMID:30503582 NCBI chr15:82,336,578...82,341,028
Ensembl chr15:82,317,638...82,341,046
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases activity
decreases expression
multiple interactions
increases expression
ISO
EXP
Rifampin results in increased activity of CYP2E1 protein
Rifampin results in decreased expression of CYP2E1 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein
Rifampin results in increased expression of CYP2E1 mRNA; Rifampin results in increased expression of CYP2E1 protein
[Rifampin co-treated with Monocrotophos] results in increased activity of CYP2E1 protein; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of CYP2E1 protein
[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein; [Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; [Methionine co-treated with Thiamine co-treated with Niacinamide co-treated with alpha-Tocopherol co-treated with Zinc] inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased activity of CYP2E1 protein]; Methionine inhibits the reaction [[Isoniazid co-treated with Rifampin co-treated with Ethambutol co-treated with Pyrazinamide] results in increased expression of CYP2E1 mRNA]; Rifampin inhibits the reaction [Isoniazid results in increased expression of CYP2E1 protein]
CTD PMID:15132840 PMID:18071298 PMID:22258563 PMID:22733800 PMID:25835148 More... NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900
JBrowse link
G Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 decreases expression ISO Rifampin results in decreased expression of CYP2F1 mRNA CTD PMID:22258563 NCBI chr 7:26,819,380...26,833,085
Ensembl chr 7:26,819,334...26,833,085
JBrowse link
G Cyp2j9 cytochrome P450, family 2, subfamily j, polypeptide 9 decreases expression ISO Rifampin results in decreased expression of CYP2J2 mRNA CTD PMID:33263786 NCBI chr 4:96,456,661...96,480,748
Ensembl chr 4:96,456,666...96,479,815
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA CTD PMID:21127053 NCBI chr 7:25,501,894...25,515,950
Ensembl chr 7:25,501,900...25,516,338
JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 multiple interactions
increases expression
EXP [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A11 mRNA; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CYP3A11 mRNA; sulforaphane inhibits the reaction [Rifampin results in increased expression of CYP3A11 mRNA]
Rifampin results in increased expression of CYP3A11 mRNA; Rifampin results in increased expression of CYP3A11 protein
CTD PMID:20869979 PMID:21224054 PMID:22467028 PMID:23153560 PMID:25835148 More... NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 increases expression ISO Rifampin results in increased expression of CYP3A7 mRNA
Rifampin results in increased expression of CYP3A5 mRNA
CTD PMID:12040753 PMID:12673034 PMID:15629111 PMID:15681896 PMID:19118567 More... NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyp3a44 cytochrome P450, family 3, subfamily a, polypeptide 44 increases activity
multiple interactions
EXP Rifampin results in increased activity of CYP3A4 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A4 protein; NR1I2 affects the reaction [Rifampin results in increased activity of CYP3A4 protein]
CTD PMID:20361990 PMID:21224054 NCBI chr 5:145,710,793...145,742,701
Ensembl chr 5:145,710,793...145,742,684
JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 multiple interactions
increases expression
EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A10 mRNA
Rifampin results in increased expression of CYP4A10 mRNA
CTD PMID:21224054 PMID:27806127 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846
JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 multiple interactions
increases expression
EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A14 mRNA
Rifampin results in increased expression of CYP4A14 mRNA
CTD PMID:21224054 PMID:27806127 NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339
JBrowse link
G Cyp7a1 cytochrome P450, family 7, subfamily a, polypeptide 1 multiple interactions
decreases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of CYP7A1 protein
Rifampin results in decreased expression of CYP7A1 mRNA
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of CYP7A1 protein; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]
CTD PMID:15629111 PMID:21127053 PMID:21224054 PMID:22258563 PMID:24259679 More... NCBI chr 4:6,265,612...6,275,632
Ensembl chr 4:6,265,612...6,275,633
JBrowse link
G Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA CTD PMID:21127053 NCBI chr 9:121,743,422...121,745,371
Ensembl chr 9:121,743,422...121,745,371
JBrowse link
G Dcaf5 DDB1 and CUL4 associated factor 5 decreases expression ISO Rifampin results in decreased expression of DCAF5 mRNA CTD PMID:24552687 NCBI chr12:80,382,622...80,483,375
Ensembl chr12:80,382,622...80,483,375
JBrowse link
G Dclre1b DNA cross-link repair 1B decreases expression ISO Rifampin results in decreased expression of DCLRE1B mRNA CTD PMID:24552687 NCBI chr 3:103,707,921...103,716,703
Ensembl chr 3:103,707,921...103,716,760
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of DDIT3 mRNA
Rifampin results in increased expression of DDIT3 mRNA; Rifampin results in increased expression of DDIT3 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of DDIT3 mRNA]
CTD PMID:21224054 PMID:27470132 PMID:32535746 PMID:33629115 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase multiple interactions ISO [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA CTD PMID:22101211 NCBI chr 4:106,418,279...106,446,310
Ensembl chr 4:106,418,235...106,446,310
JBrowse link
G Dio1 deiodinase, iodothyronine, type I increases expression ISO Rifampin results in increased expression of DIO1 mRNA CTD PMID:24552687 NCBI chr 4:107,148,662...107,164,365
Ensembl chr 4:107,148,662...107,164,366
JBrowse link
G Dlx4 distal-less homeobox 4 decreases expression ISO Rifampin results in decreased expression of DLX4 mRNA CTD PMID:24552687 NCBI chr11:95,031,273...95,037,116
Ensembl chr11:95,031,273...95,037,089
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA CTD PMID:21224054 NCBI chr 4:40,722,468...40,734,965
Ensembl chr 4:40,722,150...40,737,149
JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA CTD PMID:21224054 NCBI chr 2:154,401,320...154,411,812
Ensembl chr 2:154,401,327...154,411,812
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA CTD PMID:21127053 NCBI chr13:42,454,952...42,461,466
Ensembl chr13:42,454,952...42,461,466
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA
CTD PMID:21127053 PMID:21224054 NCBI chr18:34,994,260...34,998,009
Ensembl chr18:34,992,876...34,998,037
JBrowse link
G Egr2 early growth response 2 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA CTD PMID:21127053 NCBI chr10:67,370,334...67,383,354
Ensembl chr10:67,371,305...67,378,018
JBrowse link
G Egr4 early growth response 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA CTD PMID:21127053 NCBI chr 6:85,488,103...85,490,571
Ensembl chr 6:85,488,103...85,490,571
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation
multiple interactions
increases expression
ISO Rifampin results in increased phosphorylation of EIF2AK3 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 protein]
Rifampin results in increased expression of EIF2AK3 mRNA; Rifampin results in increased expression of EIF2AK3 protein
CTD PMID:24638036 PMID:27470132 NCBI chr 6:70,821,468...70,882,225
Ensembl chr 6:70,821,499...70,882,229
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha increases phosphorylation ISO Rifampin results in increased phosphorylation of EIF2S1 protein CTD PMID:24638036 NCBI chr12:78,908,846...78,933,784
Ensembl chr12:78,908,593...78,933,784
JBrowse link
G Elk1 ELK1, member of ETS oncogene family decreases expression ISO Rifampin results in decreased expression of ELK1 mRNA CTD PMID:24552687 NCBI chr  X:20,799,634...20,816,847
Ensembl chr  X:20,799,634...20,816,847
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA CTD PMID:21127053 NCBI chr17:87,061,292...87,140,838
Ensembl chr17:87,061,128...87,140,838
JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases expression
multiple interactions
ISO Rifampin results in increased expression of EPHX1 mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA]
CTD PMID:22258563 PMID:25313206 PMID:29356861 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signalling 1 multiple interactions
increases expression
ISO Rifampin results in increased expression of and results in increased phosphorylation of ERN1 protein
Rifampin results in increased expression of ERN1 mRNA
CTD PMID:32535746 NCBI chr11:106,285,474...106,378,701
Ensembl chr11:106,285,476...106,378,678
JBrowse link
G Etnppl ethanolamine phosphate phospholyase increases expression ISO Rifampin results in increased expression of ETNPPL mRNA CTD PMID:24552687 NCBI chr 3:130,411,097...130,429,399
Ensembl chr 3:130,411,097...130,431,170
JBrowse link
G F13b coagulation factor XIII, beta subunit increases expression ISO Rifampin results in increased expression of F13B mRNA CTD PMID:24552687 NCBI chr 1:139,429,285...139,451,496
Ensembl chr 1:139,429,440...139,451,490
JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]]; Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP3 protein]; Rifampin inhibits the reaction [FAS protein results in increased activity of CASP8 protein]; Rifampin inhibits the reaction [FAS protein results in increased expression of CFLAR protein modified form]; Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein] CTD PMID:11958592 PMID:12645856 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions
decreases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA
Rifampin results in decreased expression of FASLG mRNA; Rifampin results in decreased expression of FASLG protein
Mifepristone inhibits the reaction [Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]]; Rifampin inhibits the reaction [FAS protein results in increased expression of FASLG protein]
CTD PMID:11958592 PMID:12645856 PMID:21224054 PMID:24552687 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fasn fatty acid synthase increases expression
affects expression
multiple interactions
EXP
ISO
Rifampin results in increased expression of FASN mRNA
Rifampin affects the expression of FASN mRNA
pimecrolimus inhibits the reaction [Rifampin results in increased expression of FASN mRNA]
CTD PMID:27806127 PMID:29356861 PMID:34689256 NCBI chr11:120,696,784...120,715,992
Ensembl chr11:120,696,672...120,715,373
JBrowse link
G Fgf15 fibroblast growth factor 15 multiple interactions
increases expression
ISO [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA
Rifampin results in increased expression of FGF19 mRNA
CTD PMID:17696253 NCBI chr 7:144,450,269...144,454,690
Ensembl chr 7:144,450,268...144,454,690
JBrowse link
G Fmo1 flavin containing monooxygenase 1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA CTD PMID:21224054 NCBI chr 1:162,657,130...162,694,170
Ensembl chr 1:162,657,130...162,694,179
JBrowse link
G Fmo4 flavin containing monooxygenase 4 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA CTD PMID:21224054 NCBI chr 1:162,620,757...162,643,788
Ensembl chr 1:162,620,757...162,641,541
JBrowse link
G Foxa1 forkhead box A1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA CTD PMID:21127053 NCBI chr12:57,585,750...57,594,815
Ensembl chr12:57,587,414...57,593,702
JBrowse link
G Foxp1 forkhead box P1 increases expression ISO Rifampin results in increased expression of FOXP1 mRNA CTD PMID:24552687 NCBI chr 6:98,902,303...99,510,587
Ensembl chr 6:98,902,299...99,499,682
JBrowse link
G Fut1 fucosyltransferase 1 decreases expression ISO Rifampin results in decreased expression of FUT1 mRNA CTD PMID:24552687 NCBI chr 7:45,266,862...45,270,483
Ensembl chr 7:45,266,713...45,270,483
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 multiple interactions
decreases expression
affects expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form affects the reaction [Rifampin affects the expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]
Rifampin results in decreased expression of G6PC1 mRNA
CTD PMID:24204015 PMID:34689256 NCBI chr11:101,258,542...101,268,729
Ensembl chr11:101,258,387...101,268,729
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible 45 alpha multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA CTD PMID:21224054 NCBI chr 6:67,012,080...67,014,391
Ensembl chr 6:67,012,080...67,014,441
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta multiple interactions ISO NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA] CTD PMID:21127053 NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038
JBrowse link
G Gata5 GATA binding protein 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA CTD PMID:21127053 NCBI chr 2:179,966,881...179,977,296
Ensembl chr 2:179,966,926...179,976,492
JBrowse link
G Gck glucokinase decreases expression
multiple interactions
ISO Rifampin results in decreased expression of GCK protein
NR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]
CTD PMID:26616219 NCBI chr11:5,850,816...5,900,081
Ensembl chr11:5,850,820...5,900,081
JBrowse link
G Glis2 GLIS family zinc finger 2 increases expression ISO Rifampin results in increased expression of GLIS2 mRNA CTD PMID:24552687 NCBI chr16:4,412,217...4,443,076
Ensembl chr16:4,412,577...4,442,788
JBrowse link
G Gm14295 predicted gene 14295 increases expression ISO Rifampin results in increased expression of ZNF441 mRNA CTD PMID:24552687 NCBI chr 2:176,489,972...176,512,508
Ensembl chr 2:176,490,405...176,503,016
JBrowse link
G Gm24031 predicted gene, 24031 decreases expression ISO Rifampin results in decreased expression of SNORA71C mRNA CTD PMID:24552687 NCBI chr14:26,218,810...26,218,940
Ensembl chr14:26,218,810...26,218,940
JBrowse link
G Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type decreases expression ISO Rifampin results in decreased expression of GNAL mRNA CTD PMID:24552687 NCBI chr18:67,221,369...67,359,863
Ensembl chr18:67,221,287...67,359,863
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions
increases activity
EXP [Rifampin co-treated with Isoniazid] results in increased activity of GOT1 protein
Rifampin results in increased activity of GOT1 protein
CTD PMID:25886055 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions
increases activity
increases expression
ISO
EXP
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of GPT protein]; [Rifampin co-treated with Acetaminophen] results in decreased activity of GPT protein
Rifampin results in increased activity of GPT protein
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPT protein; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein]
[Rifampin co-treated with Isoniazid] results in increased activity of GPT protein; Rifampin inhibits the reaction [Acetaminophen results in increased expression of GPT protein]
CTD PMID:24685772 PMID:25886055 PMID:27470132 PMID:31678598 PMID:35544702 More... NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA; [Rifampin co-treated with Cobicistat] results in increased expression of GPX2 mRNA CTD PMID:21224054 PMID:33629115 NCBI chr12:76,839,109...76,842,328
Ensembl chr12:76,839,107...76,842,273
JBrowse link
G Gpx4 glutathione peroxidase 4 multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein] CTD PMID:36878459 NCBI chr10:79,883,000...79,892,273
Ensembl chr10:79,883,000...79,892,273
JBrowse link
G Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) decreases expression ISO Rifampin results in decreased expression of GRIA1 mRNA CTD PMID:24552687 NCBI chr11:56,902,342...57,221,070
Ensembl chr11:56,902,213...57,221,070
JBrowse link
G Gsr glutathione reductase increases activity EXP Rifampin results in increased activity of GSR protein CTD PMID:20848779 NCBI chr 8:34,143,266...34,188,190
Ensembl chr 8:34,142,551...34,188,191
JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein CTD PMID:21224054 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA CTD PMID:21224054 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002
JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression
multiple interactions
ISO Rifampin results in increased expression of GSTP1 mRNA; Rifampin results in increased expression of GSTP1 protein
[Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of GSTP1 protein
CTD PMID:22733800 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985
JBrowse link
G Gstt1 glutathione S-transferase, theta 1 multiple interactions ISO GSTT1 gene polymorphism affects the susceptibility to [Isoniazid co-treated with Rifampin]; GSTT1 gene polymorphism results in increased susceptibility to [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide] CTD PMID:18397238 PMID:20485159 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418
JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 increases expression ISO Rifampin results in increased expression of GTF2IRD2 mRNA CTD PMID:24552687 NCBI chr 5:134,211,629...134,246,988
Ensembl chr 5:134,212,858...134,253,209
JBrowse link
G Gzmb granzyme B increases secretion ISO Rifampin results in increased secretion of GZMB protein CTD PMID:27933861 NCBI chr14:56,496,293...56,499,791
Ensembl chr14:56,496,295...56,499,717
JBrowse link
G H2-Ab1 histocompatibility 2, class II antigen A, beta 1 affects expression ISO Rifampin affects the expression of HLA-DQB1 mRNA CTD PMID:25811541 NCBI chr17:34,482,201...34,488,392
Ensembl chr17:34,476,663...34,488,393
JBrowse link
G H2-DMa histocompatibility 2, class II, locus DMa increases expression ISO Rifampin results in increased expression of HLA-DMA mRNA CTD PMID:24552687 NCBI chr17:34,338,667...34,358,075
Ensembl chr17:34,338,515...34,358,075
JBrowse link
G H2-M3 histocompatibility 2, M region locus 3 affects expression ISO Rifampin affects the expression of HLA-G mRNA CTD PMID:25811541 NCBI chr17:37,581,094...37,585,380
Ensembl chr17:37,581,111...37,585,375
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA CTD PMID:21127053 NCBI chr18:36,637,980...36,648,858
Ensembl chr18:36,637,980...36,648,858
JBrowse link
G Hdac3 histone deacetylase 3 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr18:38,070,024...38,088,073
Ensembl chr18:38,068,897...38,088,069
JBrowse link
G Hdac5 histone deacetylase 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA CTD PMID:21127053 NCBI chr11:102,085,244...102,120,968
Ensembl chr11:102,085,258...102,120,992
JBrowse link
G Hey1 hairy/enhancer-of-split related with YRPW motif 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA CTD PMID:21127053 NCBI chr 3:8,728,419...8,732,098
Ensembl chr 3:8,728,419...8,732,316
JBrowse link
G Hgf hepatocyte growth factor multiple interactions EXP HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased abundance of Reactive Oxygen Species]; HGF protein inhibits the reaction [[Isoniazid co-treated with Rifampin] results in increased activity of CASP3 protein] CTD PMID:23764483 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hif1a hypoxia inducible factor 1, alpha subunit multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of HIF1A mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of HIF1A protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of GPX4 protein]; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein]; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of GPT protein]
CTD PMID:21127053 PMID:36878459 NCBI chr12:73,948,186...73,994,304
Ensembl chr12:73,948,149...73,994,304
JBrowse link
G Hmgn5 high-mobility group nucleosome binding domain 5 increases expression ISO Rifampin results in increased expression of HMGN5 mRNA CTD PMID:24552687 NCBI chr  X:108,048,143...108,056,986
Ensembl chr  X:108,048,140...108,057,010
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA
dorsomorphin inhibits the reaction [Rifampin results in increased expression of HMOX1 protein]
Rifampin results in increased expression of HMOX1 mRNA; Rifampin results in increased expression of HMOX1 protein
[arsenite co-treated with Rifampin] results in increased expression of HMOX1 mRNA
CTD PMID:21224054 PMID:22159698 PMID:22258563 PMID:31678598 NCBI chr 8:75,820,246...75,827,221
Ensembl chr 8:75,820,249...75,827,217
JBrowse link
G Hnf4a hepatic nuclear factor 4, alpha multiple interactions ISO [HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; allyl isothiocyanate inhibits the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; Rifampin inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [MED1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA6 protein binds to HNF4A protein]; Rifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]; Rifampin promotes the reaction [PPARGC1A protein binds to HNF4A protein] CTD PMID:21127053 PMID:21292004 PMID:21764778 PMID:25069801 NCBI chr 2:163,348,731...163,414,827
Ensembl chr 2:163,348,728...163,414,830
JBrowse link
G Hrh1 histamine receptor H1 increases expression ISO Rifampin results in increased expression of HRH1 mRNA CTD PMID:24552687 NCBI chr 6:114,374,897...114,459,432
Ensembl chr 6:114,374,897...114,460,257
JBrowse link
G Hspa1l heat shock protein 1-like multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA CTD PMID:21224054 NCBI chr17:35,191,679...35,198,204
Ensembl chr17:35,191,679...35,198,261
JBrowse link
G Hspa5 heat shock protein 5 multiple interactions
increases expression
ISO
EXP
ATF4 mutant form inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
[Rifampin co-treated with Cobicistat] results in increased expression of HSPA5 mRNA
Rifampin results in increased expression of HSPA5 mRNA; Rifampin results in increased expression of HSPA5 protein
4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 mRNA]; 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of HSPA5 protein]
CTD PMID:24638036 PMID:27470132 PMID:32535746 PMID:33629115 NCBI chr 2:34,662,102...34,666,541
Ensembl chr 2:34,661,982...34,667,559
JBrowse link
G Hspa8 heat shock protein 8 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA CTD PMID:21224054 NCBI chr 9:40,712,572...40,716,498
Ensembl chr 9:40,712,280...40,721,383
JBrowse link
G Hspb1 heat shock protein 1 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA CTD PMID:21224054 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hspd1 heat shock protein 1 (chaperonin) multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA CTD PMID:21224054 NCBI chr 1:55,116,992...55,127,402
Ensembl chr 1:55,116,994...55,127,402
JBrowse link
G Hspe1 heat shock protein 1 (chaperonin 10) multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA CTD PMID:21224054 NCBI chr 1:55,127,307...55,130,476
Ensembl chr 1:55,127,291...55,130,466
JBrowse link
G Ifng interferon gamma increases secretion ISO Rifampin results in increased secretion of IFNG protein CTD PMID:27933861 NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA CTD PMID:21127053 NCBI chr11:7,147,787...7,152,546
Ensembl chr11:7,147,782...7,152,546
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA CTD PMID:21127053 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
JBrowse link
G Igfbp4 insulin-like growth factor binding protein 4 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA CTD PMID:21127053 NCBI chr11:98,930,820...98,943,481
Ensembl chr11:98,932,070...98,945,218
JBrowse link
G Il10 interleukin 10 affects expression ISO Rifampin affects the expression of IL10 protein CTD PMID:25051504 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12rb2 interleukin 12 receptor, beta 2 decreases expression ISO Rifampin results in decreased expression of IL12RB2 mRNA CTD PMID:24552687 NCBI chr 6:67,263,914...67,353,277
Ensembl chr 6:67,268,302...67,353,172
JBrowse link
G Il13 interleukin 13 increases secretion ISO Rifampin results in increased secretion of IL13 protein CTD PMID:27933861 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529
JBrowse link
G Il18 interleukin 18 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; Rifampin inhibits the reaction [Rotenone results in increased expression of and results in increased secretion of IL1B protein]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]
Rifampin results in decreased expression of IL1B mRNA; Rifampin results in decreased expression of IL1B protein
CTD PMID:21224054 PMID:25051504 PMID:26086368 PMID:31648047 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il6 interleukin 6 decreases expression
multiple interactions
increases expression
ISO
EXP
Rifampin results in decreased expression of IL6 protein
Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]]; Rifampin inhibits the reaction [Rotenone results in increased expression of IL6 mRNA]
Rifampin results in increased expression of IL6 protein
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA
CTD PMID:21224054 PMID:21357946 PMID:25051504 PMID:31648047 NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Ino80d INO80 complex subunit D decreases expression ISO Rifampin results in decreased expression of INO80D mRNA CTD PMID:24552687 NCBI chr 1:63,086,960...63,153,693
Ensembl chr 1:62,997,577...63,153,849
JBrowse link
G Ins2 insulin II multiple interactions ISO
EXP
INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]
Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPA mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPA protein]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPB mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPB protein]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of CEBPD mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG mRNA alternative form]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG protein]
CTD PMID:24204015 PMID:33412187 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118
JBrowse link
G Ints6 integrator complex subunit 6 decreases expression ISO Rifampin results in decreased expression of INTS6 mRNA CTD PMID:24552687 NCBI chr14:62,913,774...62,998,617
Ensembl chr14:62,913,779...62,998,618
JBrowse link
G Iqca1 IQ motif containing with AAA domain 1 decreases expression ISO Rifampin results in decreased expression of IQCA1 mRNA CTD PMID:24552687 NCBI chr 1:89,969,854...90,081,158
Ensembl chr 1:89,969,854...90,081,123
JBrowse link
G Itgbl1 integrin, beta-like 1 decreases expression ISO Rifampin results in decreased expression of ITGBL1 mRNA CTD PMID:24552687 NCBI chr14:123,897,331...124,215,173
Ensembl chr14:123,897,383...124,213,030
JBrowse link
G Jun jun proto-oncogene multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA CTD PMID:21127053 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kirrel3 kirre like nephrin family adhesion molecule 3 decreases expression ISO Rifampin results in decreased expression of KIRREL3 mRNA CTD PMID:24552687 NCBI chr 9:34,396,850...34,952,103
Ensembl chr 9:34,397,190...34,948,012
JBrowse link
G Klf2 Kruppel-like transcription factor 2 (lung) multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA CTD PMID:21127053 NCBI chr 8:73,072,906...73,075,498
Ensembl chr 8:73,072,877...73,075,500
JBrowse link
G Klf5 Kruppel-like transcription factor 5 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA CTD PMID:21127053 NCBI chr14:99,536,127...99,550,848
Ensembl chr14:99,536,127...99,552,472
JBrowse link
G Klf6 Kruppel-like transcription factor 6 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA CTD PMID:21127053 NCBI chr13:5,911,488...5,920,392
Ensembl chr13:5,911,481...5,920,393
JBrowse link
G Ldlr low density lipoprotein receptor increases expression EXP Rifampin results in increased expression of LDLR mRNA CTD PMID:27806127 NCBI chr 9:21,634,872...21,661,215
Ensembl chr 9:21,634,779...21,661,215
JBrowse link
G Lefty1 left right determination factor 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA CTD PMID:21127053 NCBI chr 1:180,762,587...180,765,966
Ensembl chr 1:180,762,587...180,765,965
JBrowse link
G Lep leptin increases expression ISO Rifampin results in increased expression of LEP protein CTD PMID:25051504 NCBI chr 6:29,060,220...29,073,875
Ensembl chr 6:29,060,219...29,073,876
JBrowse link
G Ltk leukocyte tyrosine kinase increases expression ISO Rifampin results in increased expression of LTK mRNA CTD PMID:24552687 NCBI chr 2:119,581,807...119,590,912
Ensembl chr 2:119,581,801...119,590,912
JBrowse link
G Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA CTD PMID:21127053 NCBI chr15:79,230,813...79,243,278
Ensembl chr15:79,230,821...79,243,276
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta decreases metabolic processing
multiple interactions
increases lipidation
ISO Rifampin results in decreased metabolism of MAP1LC3B protein
ATP6V0D1 protein affects the reaction [Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]]; Chloroquine promotes the reaction [Rifampin results in increased lipidation of MAP1LC3B protein]; Rifampin inhibits the reaction [Rotenone results in increased lipidation of MAP1LC3B protein]
CTD PMID:29908302 PMID:31648047 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Chloroquine inhibits the reaction [Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein]]; Rifampin inhibits the reaction [Rotenone results in increased phosphorylation of MAPK8 protein] CTD PMID:31648047 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115
JBrowse link
G Mapkapk2 MAP kinase-activated protein kinase 2 increases phosphorylation ISO Rifampin results in increased phosphorylation of MAPKAPK2 protein CTD PMID:21127053 NCBI chr 1:130,981,437...131,025,580
Ensembl chr 1:130,981,437...131,025,563
JBrowse link
G Mapre3 microtubule-associated protein, RP/EB family, member 3 increases expression ISO Rifampin results in increased expression of MAPRE3 mRNA CTD PMID:24552687 NCBI chr 5:30,972,075...31,023,447
Ensembl chr 5:30,971,985...31,023,450
JBrowse link
G Matn2 matrilin 2 increases expression ISO Rifampin results in increased expression of MATN2 mRNA CTD PMID:27177772 NCBI chr15:34,306,827...34,436,388
Ensembl chr15:34,306,823...34,436,419
JBrowse link
G Mbp myelin basic protein affects expression ISO Rifampin affects the expression of MBP mRNA CTD PMID:22954530 NCBI chr18:82,492,883...82,603,762
Ensembl chr18:82,493,271...82,603,762
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 multiple interactions ISO [Rifampin inhibits the reaction [CYP2C8 protein results in increased susceptibility to Amodiaquine]] which results in decreased expression of MCL1 protein CTD PMID:31629065 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Mdm2 transformed mouse 3T3 cell double minute 2 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA CTD PMID:21224054 NCBI chr10:117,524,780...117,546,663
Ensembl chr10:117,524,780...117,546,663
JBrowse link
G Med1 mediator complex subunit 1 multiple interactions
decreases expression
ISO Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [MED1 protein binds to HNF4A protein]
Rifampin results in decreased expression of MED1 mRNA
CTD PMID:21292004 PMID:22214767 PMID:24552687 NCBI chr11:98,042,980...98,084,121
Ensembl chr11:98,042,980...98,084,119
JBrowse link
G Minpp1 multiple inositol polyphosphate histidine phosphatase 1 increases expression ISO Rifampin results in increased expression of MINPP1 mRNA CTD PMID:24552687 NCBI chr19:32,463,169...32,492,770
Ensembl chr19:32,463,169...32,492,764
JBrowse link
G Mir143 microRNA 143 increases expression ISO Rifampin results in increased expression of MIR143 mRNA CTD PMID:24552687 NCBI chr18:61,782,267...61,782,329
Ensembl chr18:61,782,267...61,782,329
JBrowse link
G Mir145a microRNA 145a increases expression ISO Rifampin results in increased expression of MIR145 mRNA CTD PMID:24552687 NCBI chr18:61,780,896...61,780,965
Ensembl chr18:61,780,896...61,780,965
JBrowse link
G Mir148b microRNA 148b decreases expression ISO Rifampin results in decreased expression of MIR148B mRNA CTD PMID:24552687 NCBI chr15:103,193,552...103,193,648
Ensembl chr15:103,193,552...103,193,648
JBrowse link
G Mir149 microRNA 149 decreases expression ISO Rifampin results in decreased expression of MIR149 mRNA CTD PMID:24552687 NCBI chr 1:92,778,100...92,778,165
Ensembl chr 1:92,778,100...92,778,165
JBrowse link
G Mir15b microRNA 15b increases expression ISO Rifampin results in increased expression of MIR15B mRNA CTD PMID:24552687 NCBI chr 3:68,917,105...68,917,168
Ensembl chr 3:68,917,105...68,917,168
JBrowse link
G Mir192 microRNA 192 decreases expression ISO Rifampin results in decreased expression of MIR192 mRNA CTD PMID:24552687 NCBI chr19:6,314,874...6,314,962
Ensembl chr19:6,314,874...6,314,962
JBrowse link
G Mir200a microRNA 200a increases expression ISO Rifampin results in increased expression of MIR200A mRNA CTD PMID:24552687 NCBI chr 4:156,139,353...156,139,442
Ensembl chr 4:156,139,353...156,139,442
JBrowse link
G Mir202 microRNA 202 increases expression ISO Rifampin results in increased expression of MIR202 mRNA CTD PMID:24552687 NCBI chr 7:139,537,602...139,537,673
Ensembl chr 7:139,537,602...139,537,673
JBrowse link
G Mir204 microRNA 204 increases expression ISO Rifampin results in increased expression of MIR204 mRNA CTD PMID:24552687 NCBI chr19:22,727,969...22,728,036
Ensembl chr19:22,727,969...22,728,036
JBrowse link
G Mir20b microRNA 20b increases expression ISO Rifampin results in increased expression of MIR20B mRNA CTD PMID:24552687 NCBI chr  X:51,830,990...51,831,069
Ensembl chr  X:51,830,990...51,831,069
JBrowse link
G Mir212 microRNA 212 decreases expression ISO Rifampin results in decreased expression of MIR212 mRNA CTD PMID:24552687 NCBI chr11:75,064,214...75,064,304
Ensembl chr11:75,064,214...75,064,304
JBrowse link
G Mir215 microRNA 215 increases expression ISO Rifampin results in increased expression of MIR215 mRNA CTD PMID:24552687 NCBI chr 1:185,045,778...185,045,889
Ensembl chr 1:185,045,778...185,045,889
JBrowse link
G Mir21a microRNA 21a increases expression ISO Rifampin results in increased expression of MIR21 mRNA CTD PMID:24552687 NCBI chr11:86,474,893...86,474,984
Ensembl chr11:86,474,893...86,474,984
JBrowse link
G Mir22 microRNA 22 increases expression ISO Rifampin results in increased expression of MIR22 mRNA CTD PMID:24552687 NCBI chr11:75,354,542...75,354,636
Ensembl chr11:75,354,542...75,354,636
JBrowse link
G Mir26b microRNA 26b increases expression ISO Rifampin results in increased expression of MIR26B mRNA CTD PMID:24552687 NCBI chr 1:74,433,469...74,433,553
Ensembl chr 1:74,433,469...74,433,553
JBrowse link
G Mir296 microRNA 296 decreases expression ISO Rifampin results in decreased expression of MIR296 mRNA CTD PMID:24552687 NCBI chr 2:174,108,840...174,108,918
Ensembl chr 2:174,108,840...174,108,918
JBrowse link
G Mir29a microRNA 29a decreases expression ISO Rifampin results in decreased expression of MIR29A mRNA CTD PMID:24552687 NCBI chr 6:31,039,595...31,039,682
Ensembl chr 6:31,039,595...31,039,682
JBrowse link
G Mir31 microRNA 31 increases expression ISO Rifampin results in increased expression of MIR31 mRNA CTD PMID:24552687 NCBI chr 4:88,828,794...88,828,899
Ensembl chr 4:88,828,794...88,828,899
JBrowse link
G Mir328 microRNA 328 increases expression ISO Rifampin results in increased expression of MIR328 mRNA CTD PMID:24552687 NCBI chr 8:106,034,996...106,035,092
Ensembl chr 8:106,034,996...106,035,092
JBrowse link
G Mir340 microRNA 340 increases expression ISO Rifampin results in increased expression of MIR340 mRNA CTD PMID:24552687 NCBI chr11:49,960,529...49,960,626
Ensembl chr11:49,960,529...49,960,626
JBrowse link
G Mir34a microRNA 34a decreases expression ISO Rifampin results in decreased expression of MIR34A mRNA CTD PMID:24552687 NCBI chr 4:150,152,911...150,153,012
Ensembl chr 4:150,152,911...150,153,012
JBrowse link
G Mir362 microRNA 362 decreases expression ISO Rifampin results in decreased expression of MIR362 mRNA CTD PMID:24552687 NCBI chr  X:7,108,221...7,108,285
Ensembl chr  X:7,108,221...7,108,285
JBrowse link
G Mir374b microRNA 374b increases expression ISO Rifampin results in increased expression of MIR374B mRNA CTD PMID:24552687 NCBI chr  X:102,616,666...102,616,760
Ensembl chr  X:102,616,666...102,616,760
JBrowse link
G Mir532 microRNA 532 decreases expression ISO Rifampin results in decreased expression of MIR532 mRNA CTD PMID:24552687 NCBI chr  X:7,114,641...7,114,736
Ensembl chr  X:7,114,641...7,114,736
JBrowse link
G Mir539 microRNA 539 increases expression ISO Rifampin results in increased expression of MIR539 mRNA CTD PMID:24552687 NCBI chr12:109,694,563...109,694,636
Ensembl chr12:109,694,563...109,694,636
JBrowse link
G Mir652 microRNA 652 decreases expression ISO Rifampin results in decreased expression of MIR652 mRNA CTD PMID:24552687 NCBI chr  X:141,521,996...141,522,093
Ensembl chr  X:141,521,996...141,522,093
JBrowse link
G Mir874 microRNA 874 decreases expression ISO Rifampin results in decreased expression of MIR874 mRNA CTD PMID:24552687 NCBI chr13:58,170,939...58,171,014
Ensembl chr13:58,170,939...58,171,014
JBrowse link
G Mirlet7e microRNA let7e increases expression ISO Rifampin results in increased expression of MIRLET7E mRNA CTD PMID:24552687 NCBI chr17:18,050,614...18,050,706
Ensembl chr17:18,050,614...18,050,706
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein CTD PMID:21224054 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mmp3 matrix metallopeptidase 3 decreases secretion ISO Rifampin results in decreased secretion of MMP3 protein CTD PMID:24890593 NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO Rifampin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased activity of MPO protein] CTD PMID:24101390 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Rifampin affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr 1:155,003,620...155,022,560
Ensembl chr 1:155,003,023...155,022,560
JBrowse link
G Mttp microsomal triglyceride transfer protein decreases expression ISO Rifampin results in decreased expression of MTTP mRNA CTD PMID:32535746 NCBI chr 3:137,795,616...137,849,179
Ensembl chr 3:137,795,615...137,850,729
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha increases expression ISO Rifampin results in increased expression of MYH6 mRNA CTD PMID:24552687 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384
JBrowse link
G Naf1 nuclear assembly factor 1 ribonucleoprotein decreases expression ISO Rifampin results in decreased expression of NAF1 mRNA CTD PMID:24552687 NCBI chr 8:67,312,594...67,343,216
Ensembl chr 8:67,312,869...67,343,216
JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 increases expression ISO Rifampin results in increased expression of NAP1L5 mRNA CTD PMID:24552687 NCBI chr 6:58,882,218...58,884,111
Ensembl chr 6:58,882,218...58,884,061
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO Camptothecin inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Itraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Miconazole promotes the reaction [Rifampin results in increased expression of NCOA1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; oxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; pazopanib inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pimecrolimus inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Rifampin inhibits the reaction [NCOA1 protein binds to SLC22A1 promoter]; Rifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]; Rifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to HNF4A protein]; Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein] CTD PMID:11581012 PMID:12072427 PMID:16819505 PMID:17088262 PMID:17438109 More... NCBI chr12:4,297,362...4,569,452
Ensembl chr12:4,297,362...4,527,182
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO Rifampin promotes the reaction [NCOA2 protein binds to HNF4A protein] CTD PMID:21292004 NCBI chr 1:13,209,329...13,444,451
Ensembl chr 1:13,209,329...13,444,307
JBrowse link
G Ncoa6 nuclear receptor coactivator 6 multiple interactions ISO NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NCOA6] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NCOA6 protein binds to HNF4A protein] CTD PMID:21292004 NCBI chr 2:155,232,585...155,315,741
Ensembl chr 2:155,232,576...155,315,814
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 multiple interactions ISO Rifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein] CTD PMID:22214767 NCBI chr11:62,207,132...62,348,200
Ensembl chr11:62,207,252...62,349,367
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 multiple interactions ISO [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; Rifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Rifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; Rifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein] CTD PMID:12072427 PMID:22214767 PMID:25313206 PMID:26883953 PMID:28289823 More... NCBI chr 5:125,094,217...125,256,302
Ensembl chr 5:125,094,217...125,256,283
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 increases expression
decreases activity
multiple interactions
ISO
EXP
Rifampin results in increased expression of NFE2L2 protein
Rifampin results in decreased activity of NFE2L2 protein
Rifampin inhibits the reaction [arsenite results in increased activity of NFE2L2 protein]
CTD PMID:31678598 PMID:33412187 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfya nuclear transcription factor-Y alpha decreases expression ISO Rifampin results in decreased expression of NFYA mRNA CTD PMID:24552687 NCBI chr17:48,693,917...48,716,782
Ensembl chr17:48,693,913...48,716,934
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions EXP Rifampin inhibits the reaction [Rotenone results in increased expression of NLRP3 protein] CTD PMID:26086368 NCBI chr11:59,432,395...59,457,781
Ensembl chr11:59,432,394...59,457,782
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions
increases expression
EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA
Rifampin results in increased expression of NOS2 mRNA
CTD PMID:21224054 PMID:24552687 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Npas1 neuronal PAS domain protein 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA CTD PMID:21127053 NCBI chr 7:16,189,643...16,210,741
Ensembl chr 7:16,189,646...16,211,653
JBrowse link
G Nppb natriuretic peptide type B multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA CTD PMID:21127053 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression
decreases expression
ISO Rifampin results in increased expression of NR0B2 mRNA
Rifampin results in decreased expression of NR0B2 mRNA
CTD PMID:15670600 PMID:34689256 NCBI chr 4:133,280,687...133,283,997
Ensembl chr 4:133,280,687...133,283,847
JBrowse link
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 multiple interactions ISO NR1H3 mutant form inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA] CTD PMID:23732298 NCBI chr 2:91,014,406...91,033,189
Ensembl chr 2:91,014,406...91,033,179
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] affects the expression of NR1H4 CTD PMID:35835356 NCBI chr10:89,290,096...89,369,484
Ensembl chr10:89,290,096...89,369,447
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 affects response to substance
decreases acetylation
affects localization
increases response to substance
increases activity
decreases response to substance
multiple interactions
increases expression
increases localization
affects binding
ISO
EXP
NR1I2 protein affects the susceptibility to Rifampin
Rifampin results in decreased acetylation of NR1I2 protein
Rifampin affects the localization of NR1I2 protein
NR1I2 protein results in increased susceptibility to Rifampin
[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein; Rifampin results in increased activity of NR1I2 protein
NR1I2 protein mutant form results in decreased susceptibility to Rifampin
1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; [[Rifampin results in increased activity of NR1I2 protein] which results in increased activity of CYP3A4 protein] which results in increased metabolism of and results in increased activity of and results in increased susceptibility to Cobicistat; [fexofenadine co-treated with Rifampin] results in increased activity of NR1I2 protein; [Ketoconazole co-treated with Rifampin] results in increased activity of NR1I2 protein; [Loperamide co-treated with Rifampin] results in increased activity of NR1I2 protein; [NR1I2 protein binds to NCOR2 protein] inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; [NR1I2 protein co-treated with Rifampin] results in decreased expression of CYP3A4 mRNA; [NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein co-treated with Rifampin] results in decreased expression of SULT1E1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein; [NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin binds to and results in increased activity of NR1I2 protein] promotes the reaction [ABCB1 protein results in decreased uptake of Doxorubicin]; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin binds to and results in increased activity of NR1I2 protein] which results in increased expression of FGF19 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I2 protein; [Rifampin co-treated with NR1I2 protein] results in decreased expression of CYP8B1 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of FOXA1 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of GATA5 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HDAC5 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of HNF4A mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of SERPINA4 mRNA; [Rifampin co-treated with NR1I2 protein] results in decreased expression of STAT5A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of ANGPTL4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of AQP3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of BHLHE40 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of BMP4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCN1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CCR7 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CDKN2B mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP26A1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2B6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP2S1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EDN1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EGR4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HBEGF mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HEY1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of HIF1A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of IGFBP4 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of JUN mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF5 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of KLF6 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of LEFTY1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of MAFF mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of NPAS1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of NPPB mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB8 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB9 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 protein; [Rifampin co-treated with NR1I2 protein] results in increased expression of SMAD9 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SOCS3 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of VEGFD mRNA; [Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCB1 protein; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of ABCC3 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP2B6 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [Rifampin results in increased activity of NR1I2 protein] which results in increased expression of DHCR24 mRNA; [Rifampin results in increased expression of NR1I2 protein] which results in increased expression of and results in increased activity of CYP3A4 protein; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Camptothecin inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; Camptothecin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; caraway oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Clove Oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; coriander oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; Doxorubicin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; enilconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Epirubicin inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Fluconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; hydroxyitraconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; INS protein inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; Itraconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Itraconazole promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]; jasmine oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]]; Ketoconazole inhibits the reaction [Rifampin binds to and results in increased activity of NR1I2 protein]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Ketoconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Ketoconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; lemongrass oil inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Miconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 mRNA]; mulberroside A inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in increased expression of ABCB1 protein]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; NCOA6 promotes the reaction [Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]]; NR1I2 gene promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of amprenavir]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Midazolam]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Nelfinavir]; NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Saquinavir]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 mRNA promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of and results in increased activity of CYP2B6 protein]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP2C9 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein affects the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein inhibits the reaction [[Rifampin co-treated with Benzo(a)pyrene] results in increased expression of AHR mRNA]; NR1I2 protein inhibits the reaction [Thapsigargin inhibits the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[HNF4A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of GCK protein]; NR1I2 protein promotes the reaction [Rifampin results in decreased expression of SLC2A2 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased abundance of Lipids]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of ABCB1 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CES2 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP24A1 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 protein]; NR1I2 protein promotes the reaction [Rifampin results in increased expression of GADD45B mRNA]; ochratoxin A inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; Oils, Volatile inhibits the reaction [Rifampin results in increased expression of NR1I2 mRNA]; Oils, Volatile promotes the reaction [Rifampin results in increased expression of NR1I2 mRNA]; oxiconazole inhibits the reaction [Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]]; oxiconazole inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; oxiconazole promotes the reaction [Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; pazopanib inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pazopanib inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; pimecrolimus inhibits the reaction [Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]]; pimecrolimus inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; Rifampin binds to and results in increased activity of NR1I2 protein; Rifampin inhibits the reaction [NCOR1 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to and results in decreased activity of NR1I2 protein]; Rifampin inhibits the reaction [NCOR2 protein binds to NR1I2 protein]; Rifampin inhibits the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin inhibits the reaction [oxiconazole promotes the reaction [NR1I2 protein binds to NCOA1 protein]]; Rifampin inhibits the reaction [oxiconazole results in increased expression of NR1I2 mRNA]; Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]]; Rifampin inhibits the reaction [trichostatin A results in increased acetylation of NR1I2 protein]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [[HNF4A co-treated with NR1I2] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NCOA1 protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [[NR1I2 protein binds to NCOA1 protein] which binds to CYP27A1 gene]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [MED1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to and results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [NCOA1 protein binds to NR1I2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to ABCB1 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP24A1 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to CYP3A4 promoter]; Rifampin promotes the reaction [NR1I2 protein binds to HNF4A protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOA1 protein]; Rifampin promotes the reaction [NR1I2 protein binds to NCOR2 protein]; Rifampin promotes the reaction [NR1I2 protein binds to SGK2 promoter]; Rifampin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP2C9 mRNA]; Rifampin promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [NR1I2 results in increased expression of CYP3A4 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]; sodium arsenite inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; sulforaphane inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]; trichostatin A affects the reaction [Rifampin affects the localization of NR1I2 protein]; triptolide inhibits the reaction [Rifampin results in increased activity of NR1I2 protein]
Rifampin results in increased expression of NR1I2 mRNA; Rifampin results in increased expression of NR1I2 protein
Rifampin results in increased localization of NR1I2 protein
[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA; [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; arsenite inhibits the reaction [Rifampin results in increased localization of NR1I2 protein]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]; sodium arsenite inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of CYP3A23-3A1 mRNA]
Rifampin binds to NR1I2 gene mutant form
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CES2A mRNA; [Rifampin binds to NR1I2 gene mutant form] which results in increased expression of CYP3A11 mRNA; [Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; NR1I2 affects the reaction [Rifampin results in increased activity of CYP3A4 protein]; Rifampin affects the localization of and results in increased activity of NR1I2 protein; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
[Rifampin binds to NR1I2 protein] which binds to CYP2C8 promoter; Rifampin binds to NR1I2 protein
CTD PMID:11581012 PMID:12065438 PMID:12072427 PMID:12370413 PMID:12417264 More... NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases expression
multiple interactions
ISO
EXP
Rifampin results in increased expression of NR1I3 mRNA
[[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP1A2 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in decreased expression of CYP2E1 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2B10 protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP2C protein; [[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin] which results in increased expression of CYP3A11 protein
Rifampin results in increased expression of NR1I3 mRNA; Rifampin results in increased expression of NR1I3 protein
[NR1I3 protein co-treated with NR1I2 protein] results in increased susceptibility to Rifampin; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 mRNA; [Rifampin co-treated with Monocrotophos] results in increased expression of NR1I3 protein
CTD PMID:19118567 PMID:22733800 PMID:25835148 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions
increases expression
ISO Dexamethasone promotes the reaction [NR3C1 protein affects the reaction [NR1I2 protein promotes the reaction [Rifampin results in increased expression of CYP2B6 mRNA]]]; NR3C1 protein promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]
Rifampin results in increased expression of NR3C1 mRNA
CTD PMID:10219967 PMID:12673034 PMID:12695351 NCBI chr18:39,543,598...39,652,485
Ensembl chr18:39,543,598...39,652,474
JBrowse link
G Nrl neural retina leucine zipper gene increases expression ISO Rifampin results in increased expression of NRL mRNA CTD PMID:24552687 NCBI chr14:55,756,973...55,762,438
Ensembl chr14:55,756,435...55,762,438
JBrowse link
G Obsl1 obscurin-like 1 decreases expression ISO Rifampin results in decreased expression of OBSL1 mRNA CTD PMID:24552687 NCBI chr 1:75,462,469...75,483,134
Ensembl chr 1:75,455,954...75,483,096
JBrowse link
G Ocln occludin affects localization EXP Rifampin affects the localization of OCLN protein CTD PMID:19577586 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Or4a47 olfactory receptor family 4 subfamily A member 47 decreases expression ISO Rifampin results in decreased expression of OR4A47 mRNA CTD PMID:24552687 NCBI chr 2:89,665,367...89,666,287
Ensembl chr 2:89,655,655...89,671,899
JBrowse link
G P4hb prolyl 4-hydroxylase, beta polypeptide decreases expression ISO Rifampin results in decreased expression of P4HB mRNA CTD PMID:32535746 NCBI chr11:120,451,124...120,464,079
Ensembl chr11:120,451,124...120,464,079
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions ISO Rifampin inhibits the reaction [[Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of PARP1 protein] CTD PMID:31678598 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pax7 paired box 7 decreases expression ISO Rifampin results in decreased expression of PAX7 mRNA CTD PMID:24552687 NCBI chr 4:139,464,357...139,560,841
Ensembl chr 4:139,464,373...139,560,839
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic multiple interactions
increases expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]
Rifampin results in increased expression of PCK1 mRNA
CTD PMID:24204015 PMID:34689256 NCBI chr 2:172,994,866...173,001,067
Ensembl chr 2:172,994,841...173,001,066
JBrowse link
G Pclaf PCNA clamp associated factor increases expression ISO Rifampin results in increased expression of PCLAF mRNA CTD PMID:24552687 NCBI chr 9:65,797,605...65,810,833
Ensembl chr 9:65,797,519...65,810,548
JBrowse link
G Pdap1 PDGFA associated protein 1 decreases expression ISO Rifampin results in decreased expression of PDAP1 mRNA CTD PMID:24552687 NCBI chr 5:145,065,580...145,076,835
Ensembl chr 5:145,065,579...145,077,048
JBrowse link
G Pde4d phosphodiesterase 4D, cAMP specific decreases expression ISO Rifampin results in decreased expression of PDE4D mRNA CTD PMID:24552687 NCBI chr13:108,790,711...110,092,503
Ensembl chr13:108,586,482...110,089,995
JBrowse link
G Peg3 paternally expressed 3 increases expression ISO Rifampin results in increased expression of PEG3 mRNA CTD PMID:24552687 NCBI chr 7:6,706,891...6,733,443
Ensembl chr 7:6,706,891...6,733,430
JBrowse link
G Pias1 protein inhibitor of activated STAT 1 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr 9:62,785,648...62,888,161
Ensembl chr 9:62,785,650...62,895,206
JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha decreases expression ISO Rifampin results in decreased expression of PILRA mRNA CTD PMID:24552687 NCBI chr 5:137,820,214...137,834,540
Ensembl chr 5:137,820,214...137,834,543
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of PIP4K2A mRNA CTD PMID:21127053 NCBI chr 2:18,847,066...19,003,101
Ensembl chr 2:18,847,066...19,002,937
JBrowse link
G Pkd2l1 polycystic kidney disease 2-like 1 decreases expression ISO Rifampin results in decreased expression of PKD2L1 mRNA CTD PMID:24552687 NCBI chr19:44,136,076...44,235,355
Ensembl chr19:44,136,076...44,180,881
JBrowse link
G Pklr pyruvate kinase liver and red blood cell increases expression ISO Rifampin results in increased expression of PKLR mRNA CTD PMID:24552687 NCBI chr 3:89,043,429...89,054,122
Ensembl chr 3:89,043,449...89,054,091
JBrowse link
G Plat plasminogen activator, tissue decreases expression ISO Rifampin results in decreased expression of PLAT mRNA CTD PMID:24552687 NCBI chr 8:23,247,655...23,272,864
Ensembl chr 8:23,247,743...23,272,860
JBrowse link
G Pon1 paraoxonase 1 increases expression ISO Rifampin results in increased expression of PON1 mRNA CTD PMID:26434531 NCBI chr 6:5,168,101...5,193,824
Ensembl chr 6:5,168,090...5,193,946
JBrowse link
G Por cytochrome p450 oxidoreductase increases activity EXP Rifampin results in increased activity of POR protein CTD PMID:12051692 NCBI chr 5:135,698,894...135,764,180
Ensembl chr 5:135,698,887...135,764,180
JBrowse link
G Pou2f1 POU domain, class 2, transcription factor 1 decreases expression ISO Rifampin results in decreased expression of POU2F1 mRNA CTD PMID:16837569 NCBI chr 1:165,692,719...165,830,318
Ensembl chr 1:165,692,723...165,830,247
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO
EXP
[Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA
[Isoniazid co-treated with Rifampin] results in decreased expression of PPARA protein
CTD PMID:16292757 PMID:36347327 NCBI chr15:85,619,112...85,691,052
Ensembl chr15:85,619,184...85,687,020
JBrowse link
G Pparg peroxisome proliferator activated receptor gamma multiple interactions
increases expression
EXP [Isoniazid co-treated with Rifampin] results in decreased expression of PPARG protein; [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of PPARG mRNA; [Rifampin affects the susceptibility to Dietary Fats] which results in decreased expression of PPARG mRNA alternative form; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG mRNA alternative form]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG mRNA]; Rifampin inhibits the reaction [[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Rosiglitazone co-treated with Indomethacin] results in increased expression of PPARG protein]; Rifampin results in increased expression of and affects the localization of PPARG protein
Rifampin results in increased expression of PPARG mRNA
CTD PMID:27806127 PMID:33412187 PMID:36347327 NCBI chr 6:115,337,828...115,467,365
Ensembl chr 6:115,337,912...115,467,360
JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha multiple interactions ISO [PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[PPARGC1A protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; Rifampin promotes the reaction [PPARGC1A protein binds to CYP2A6 promoter]; Rifampin promotes the reaction [PPARGC1A protein binds to HNF4A protein] CTD PMID:16857725 PMID:21292004 PMID:25069801 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068
JBrowse link
G Prkdc protein kinase, DNA activated, catalytic polypeptide multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC gene mutant form] results in increased expression of MKI67 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of ATM protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CCND1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CHEK2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP1B1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2A5 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP2B9 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP4A14 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of DNAJA1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of EGR1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FASL mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of FMO4 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPD1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of HSPE1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL1B mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of RAD50 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TNFSF10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TRADD mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of ANXA5 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BAX mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of BCL2L1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CCNG1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CDKN1A protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CXCL10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP2B10 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A11 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of CYP3A4 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of DDIT3 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of E2F1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GADD45A mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GPX2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM1 protein; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of GSTM3 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HMOX1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA1L mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPA8 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of HSPB1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of IL6 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of MDM2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of NOS2 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA; [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of UNG mRNA; PRKDC gene mutant form results in increased susceptibility to [Rifampin co-treated with Phenytoin co-treated with Monocrotaline] CTD PMID:21224054 NCBI chr16:15,455,698...15,660,103
Ensembl chr16:15,455,730...15,660,099
JBrowse link
G Prmt1 protein arginine N-methyltransferase 1 multiple interactions ISO PRMT1 protein affects the reaction [[Dimethyl Sulfoxide results in increased susceptibility to Rifampin] which results in increased expression of CYP3A4 mRNA]; PRMT1 protein affects the reaction [Dimethyl Sulfoxide promotes the reaction [Rifampin results in increased expression of CYP3A4 mRNA]]; PRMT1 protein affects the reaction [Rifampin results in increased expression of CYP3A4 mRNA] CTD PMID:31877331 NCBI chr 7:44,626,179...44,635,844
Ensembl chr 7:44,625,413...44,635,992
JBrowse link
G Prune1 prune exopolyphosphatase decreases expression ISO Rifampin results in decreased expression of PRUNE1 mRNA CTD PMID:24552687 NCBI chr 3:95,160,985...95,190,817
Ensembl chr 3:95,160,985...95,189,387
JBrowse link
G Psip1 PC4 and SFRS1 interacting protein 1 increases expression ISO Rifampin results in increased expression of PSIP1 mRNA CTD PMID:24552687 NCBI chr 4:83,373,917...83,404,700
Ensembl chr 4:83,373,917...83,404,696
JBrowse link
G Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein increases expression ISO Rifampin results in increased expression of PSMC3IP mRNA CTD PMID:24552687 NCBI chr11:100,981,238...100,986,261
Ensembl chr11:100,982,649...100,986,262
JBrowse link
G Rad50 RAD50 double strand break repair protein multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of RAD50 mRNA CTD PMID:21224054 NCBI chr11:53,540,346...53,598,146
Ensembl chr11:53,540,346...53,598,146
JBrowse link
G Ric8b RIC8 guanine nucleotide exchange factor B decreases expression ISO Rifampin results in decreased expression of RIC8B mRNA CTD PMID:24552687 NCBI chr10:84,753,136...84,854,201
Ensembl chr10:84,753,480...84,854,201
JBrowse link
G Rnf6 ring finger protein (C3H2C3 type) 6 decreases expression ISO Rifampin results in decreased expression of RNF6 mRNA CTD PMID:24552687 NCBI chr 5:146,146,003...146,158,267
Ensembl chr 5:146,146,002...146,158,365
JBrowse link
G Rragb Ras-related GTP binding B decreases expression ISO Rifampin results in decreased expression of RRAGB mRNA CTD PMID:24552687 NCBI chr  X:151,920,640...151,973,188
Ensembl chr  X:151,922,977...151,954,939
JBrowse link
G Rspo3 R-spondin 3 decreases expression ISO Rifampin results in decreased expression of RSPO3 mRNA CTD PMID:24552687 NCBI chr10:29,329,102...29,411,863
Ensembl chr10:29,328,412...29,411,863
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO
EXP
1,5-benzothiazepine analog promotes the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; 7-acetoxy-6,7-dihydro-6-(4-methoxyphenyl)pyrrolo(2,1-d)(1,5)benzothiazepine inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA; [Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein; [RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[RXRA protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; PK 11195 inhibits the reaction [[Rifampin co-treated with RXRA] results in increased activity of NR1I2 protein]; Rifampin promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to CYP3A23-3A1 promoter]; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]
CTD PMID:12370413 PMID:16292757 PMID:16632523 PMID:21315811 PMID:25069801 NCBI chr 2:27,566,457...27,653,331
Ensembl chr 2:27,566,452...27,652,969
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression ISO Rifampin results in decreased expression of SCARB1 mRNA; Rifampin results in decreased expression of SCARB1 protein CTD PMID:15883047 NCBI chr 5:125,354,151...125,418,082
Ensembl chr 5:125,354,151...125,418,158
JBrowse link
G Scd1 stearoyl-Coenzyme A desaturase 1 increases expression EXP Rifampin results in increased expression of SCD1 mRNA CTD PMID:27806127 NCBI chr19:44,382,889...44,396,148
Ensembl chr19:44,382,894...44,396,318
JBrowse link
G Septin8 septin 8 increases expression ISO Rifampin results in increased expression of SEPTIN8 mRNA CTD PMID:24552687 NCBI chr11:53,410,224...53,440,432
Ensembl chr11:53,410,084...53,440,392
JBrowse link
G Serpina4-ps1 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of SERPINA4 mRNA CTD PMID:21127053 NCBI chr12:104,044,218...104,053,179
Ensembl chr12:104,046,908...104,052,983
JBrowse link
G Serpinb1a serine (or cysteine) peptidase inhibitor, clade B, member 1a multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB1 mRNA CTD PMID:21127053 NCBI chr13:33,026,075...33,037,189
Ensembl chr13:33,026,075...33,035,168
JBrowse link
G Serpinb8 serine (or cysteine) peptidase inhibitor, clade B, member 8 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB8 mRNA CTD PMID:21127053 NCBI chr 1:107,517,668...107,536,708
Ensembl chr 1:107,517,736...107,538,214
JBrowse link
G Serpinb9 serine (or cysteine) peptidase inhibitor, clade B, member 9 multiple interactions
increases expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINB9 mRNA
Rifampin results in increased expression of SERPINB9 mRNA
CTD PMID:21127053 PMID:24552687 NCBI chr13:33,181,044...33,201,938
Ensembl chr13:33,187,233...33,201,940
JBrowse link
G Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 multiple interactions EXP
ISO
[Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA
CTD PMID:21127053 PMID:21224054 NCBI chr 5:137,090,358...137,101,126
Ensembl chr 5:137,090,358...137,101,122
JBrowse link
G Sfxn1 sideroflexin 1 decreases expression ISO Rifampin results in decreased expression of SFXN1 mRNA CTD PMID:24552687 NCBI chr13:54,225,675...54,262,365
Ensembl chr13:54,225,888...54,262,361
JBrowse link
G Sgk2 serum/glucocorticoid regulated kinase 2 multiple interactions
increases expression
ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 mRNA; [Rifampin co-treated with NR1I2 protein] results in increased expression of SGK2 protein; Rifampin promotes the reaction [NR1I2 protein binds to SGK2 promoter]; SGK2 mutant form affects the reaction [Rifampin affects the expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of G6PC1 mRNA]; SGK2 mutant form inhibits the reaction [[Rifampin co-treated with NR1I2 protein] results in increased expression of PCK1 mRNA]
Rifampin results in increased expression of SGK2 mRNA
CTD PMID:21127053 PMID:24204015 NCBI chr 2:162,829,249...162,856,059
Ensembl chr 2:162,829,250...162,856,047
JBrowse link
G Sik2 salt inducible kinase 2 decreases expression ISO Rifampin results in decreased expression of SIK2 mRNA CTD PMID:24552687 NCBI chr 9:50,800,944...50,920,432
Ensembl chr 9:50,804,101...50,920,373
JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 decreases expression
multiple interactions
ISO
EXP
Rifampin results in decreased expression of SLC10A1 mRNA
Rifampin results in decreased expression of SLC10A1 protein
[Rifampin co-treated with Isoniazid] results in decreased expression of SLC10A1 protein
[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in increased expression of SLC10A1
CTD PMID:16837569 PMID:25886055 PMID:35835356 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479
JBrowse link
G Slc13a5 solute carrier family 13 (sodium-dependent citrate transporter), member 5 increases expression ISO Rifampin results in increased expression of SLC13A5 mRNA; Rifampin results in increased expression of SLC13A5 protein CTD PMID:25628225 PMID:27199754 NCBI chr11:72,132,816...72,158,092
Ensembl chr11:72,132,815...72,158,048
JBrowse link
G Slc15a1 solute carrier family 15 (oligopeptide transporter), member 1 decreases expression ISO Rifampin results in decreased expression of SLC15A1 mRNA CTD PMID:27199754 NCBI chr14:121,697,033...121,742,666
Ensembl chr14:121,697,033...121,742,664
JBrowse link
G Slc16a12 solute carrier family 16 (monocarboxylic acid transporters), member 12 increases expression
decreases expression
ISO Rifampin results in increased expression of SLC16A12 mRNA
Rifampin results in decreased expression of SLC16A12 mRNA
CTD PMID:24552687 PMID:27199754 NCBI chr19:34,645,801...34,725,223
Ensembl chr19:34,645,803...34,724,689
JBrowse link
G Slc17a1 solute carrier family 17 (sodium phosphate), member 1 decreases expression ISO Rifampin results in decreased expression of SLC17A1 mRNA CTD PMID:27199754 NCBI chr13:24,051,607...24,079,713
Ensembl chr13:24,051,733...24,079,713
JBrowse link
G Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 decreases expression ISO Rifampin results in decreased expression of SLC1A2 mRNA CTD PMID:27199754 NCBI chr 2:102,488,584...102,621,129
Ensembl chr 2:102,489,004...102,621,129
JBrowse link
G Slc20a2 solute carrier family 20, member 2 decreases expression ISO Rifampin results in decreased expression of SLC20A2 mRNA CTD PMID:27199754 NCBI chr 8:22,966,771...23,059,632
Ensembl chr 8:22,966,804...23,059,628
JBrowse link
G Slc22a1 solute carrier family 22 (organic cation transporter), member 1 decreases expression
multiple interactions
ISO Rifampin results in decreased expression of SLC22A1 mRNA; Rifampin results in decreased expression of SLC22A1 protein
[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA; [NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA; NCOA1 protein inhibits the reaction [[NR1I2 protein co-treated with Rifampin] results in decreased expression of SLC22A1 mRNA]; NCOA1 protein inhibits the reaction [[NR1I2 protein results in increased susceptibility to Rifampin] which results in decreased expression of SLC22A1 mRNA]; Rifampin inhibits the reaction [NCOA1 protein binds to SLC22A1 promoter]; Rifampin promotes the reaction [NR1I2 protein results in decreased expression of SLC22A1 mRNA]
CTD PMID:26920453 PMID:27199754 NCBI chr17:12,867,761...12,894,725
Ensembl chr17:12,867,756...12,894,716
JBrowse link
G Slc22a19 solute carrier family 22 (organic anion transporter), member 19 decreases expression ISO Rifampin results in decreased expression of SLC22A9 mRNA CTD PMID:27199754 NCBI chr19:7,650,440...7,688,675
Ensembl chr19:7,650,426...7,688,675
JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 decreases expression ISO Rifampin results in decreased expression of SLC22A7 mRNA CTD PMID:16837569 PMID:27199754 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383
JBrowse link
G Slc23a2 solute carrier family 23 (nucleobase transporters), member 2 increases expression ISO Rifampin results in increased expression of SLC23A2 mRNA CTD PMID:27199754 NCBI chr 2:131,894,416...131,987,287
Ensembl chr 2:131,894,416...131,987,028
JBrowse link
G Slc23a3 solute carrier family 23 (nucleobase transporters), member 3 decreases expression ISO Rifampin results in decreased expression of SLC23A3 mRNA CTD PMID:27199754 NCBI chr 1:75,102,185...75,112,113
Ensembl chr 1:75,102,185...75,110,534
JBrowse link
G Slc25a22 solute carrier family 25 (mitochondrial carrier, glutamate), member 22 increases expression ISO Rifampin results in increased expression of SLC25A22 mRNA CTD PMID:27199754 NCBI chr 7:141,009,662...141,017,787
Ensembl chr 7:141,009,657...141,017,805
JBrowse link
G Slc25a34 solute carrier family 25, member 34 decreases expression ISO Rifampin results in decreased expression of SLC25A34 mRNA CTD PMID:27199754 NCBI chr 4:141,346,130...141,351,202
Ensembl chr 4:141,346,135...141,351,132
JBrowse link
G Slc25a40 solute carrier family 25, member 40 decreases expression ISO Rifampin results in decreased expression of SLC25A40 mRNA CTD PMID:24552687 NCBI chr 5:8,472,730...8,504,840
Ensembl chr 5:8,472,850...8,504,797
JBrowse link
G Slc26a2 solute carrier family 26 (sulfate transporter), member 2 decreases expression ISO Rifampin results in decreased expression of SLC26A2 mRNA CTD PMID:27199754 NCBI chr18:61,329,926...61,344,668
Ensembl chr18:61,325,991...61,344,684
JBrowse link
G Slc26a4 solute carrier family 26, member 4 decreases expression ISO Rifampin results in decreased expression of SLC26A4 mRNA CTD PMID:27199754 NCBI chr12:31,569,813...31,610,054
Ensembl chr12:31,569,826...31,609,968
JBrowse link
G Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 increases expression EXP Rifampin results in increased expression of SLC27A1 mRNA CTD PMID:27806127 NCBI chr 8:72,021,372...72,039,951
Ensembl chr 8:72,021,526...72,039,946
JBrowse link
G Slc27a2 solute carrier family 27 (fatty acid transporter), member 2 increases expression ISO Rifampin results in increased expression of SLC27A2 mRNA CTD PMID:27199754 NCBI chr 2:126,394,944...126,430,163
Ensembl chr 2:126,394,327...126,430,163
JBrowse link
G Slc27a3 solute carrier family 27 (fatty acid transporter), member 3 decreases expression ISO Rifampin results in decreased expression of SLC27A3 mRNA CTD PMID:27199754 NCBI chr 3:90,292,540...90,298,693
Ensembl chr 3:90,292,546...90,297,245
JBrowse link
G Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 increases expression ISO Rifampin results in increased expression of SLC27A5 mRNA CTD PMID:27199754 NCBI chr 7:12,722,273...12,732,119
Ensembl chr 7:12,722,273...12,732,119
JBrowse link
G Slc29a1 solute carrier family 29 (nucleoside transporters), member 1 increases expression ISO Rifampin results in increased expression of SLC29A1 mRNA CTD PMID:27199754 NCBI chr17:45,896,126...45,910,544
Ensembl chr17:45,896,126...45,910,532
JBrowse link
G Slc29a4 solute carrier family 29 (nucleoside transporters), member 4 increases expression ISO Rifampin results in increased expression of SLC29A4 mRNA CTD PMID:27199754 NCBI chr 5:142,678,226...142,708,245
Ensembl chr 5:142,678,267...142,708,245
JBrowse link
G Slc2a12 solute carrier family 2 (facilitated glucose transporter), member 12 increases expression ISO Rifampin results in increased expression of SLC2A12 mRNA CTD PMID:27199754 NCBI chr10:22,488,821...22,579,779
Ensembl chr10:22,520,910...22,580,184
JBrowse link
G Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 multiple interactions
decreases expression
ISO NR1I2 protein promotes the reaction [Rifampin results in decreased expression of SLC2A2 protein]
Rifampin results in decreased expression of SLC2A2 mRNA; Rifampin results in decreased expression of SLC2A2 protein
CTD PMID:26616219 PMID:27199754 PMID:34689256 NCBI chr 3:28,752,052...28,782,510
Ensembl chr 3:28,752,052...28,785,508
JBrowse link
G Slc30a10 solute carrier family 30, member 10 decreases expression ISO Rifampin results in decreased expression of SLC30A10 mRNA CTD PMID:27199754 NCBI chr 1:185,187,045...185,200,959
Ensembl chr 1:185,187,045...185,200,959
JBrowse link
G Slc38a2 solute carrier family 38, member 2 decreases expression ISO Rifampin results in decreased expression of SLC38A2 mRNA CTD PMID:27199754 NCBI chr15:96,585,267...96,597,609
Ensembl chr15:96,585,273...96,597,611
JBrowse link
G Slc3a1 solute carrier family 3, member 1 decreases expression ISO Rifampin results in decreased expression of SLC3A1 mRNA CTD PMID:27199754 NCBI chr17:85,335,775...85,371,669
Ensembl chr17:85,335,804...85,371,664
JBrowse link
G Slc46a3 solute carrier family 46, member 3 increases expression ISO Rifampin results in increased expression of SLC46A3 mRNA CTD PMID:27199754 NCBI chr 5:147,812,707...147,831,670
Ensembl chr 5:147,815,247...147,831,625
JBrowse link
G Slc47a1 solute carrier family 47, member 1 increases expression ISO Rifampin results in increased expression of SLC47A1 mRNA CTD PMID:27199754 NCBI chr11:61,234,226...61,269,668
Ensembl chr11:61,234,227...61,269,171
JBrowse link
G Slc51a solute carrier family 51, alpha subunit increases expression ISO Rifampin results in increased expression of SLC51A mRNA CTD PMID:27199754 NCBI chr16:32,294,396...32,306,697
Ensembl chr16:32,293,322...32,306,697
JBrowse link
G Slc51b solute carrier family 51, beta subunit increases expression ISO Rifampin results in increased expression of SLC51B mRNA CTD PMID:27199754 NCBI chr 9:65,320,035...65,330,055
Ensembl chr 9:65,319,996...65,330,237
JBrowse link
G Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 increases expression ISO Rifampin results in increased expression of SLC5A11 mRNA CTD PMID:27199754 NCBI chr 7:122,813,817...122,873,612
Ensembl chr 7:122,814,003...122,872,476
JBrowse link
G Slc5a12 solute carrier family 5 (sodium/glucose cotransporter), member 12 increases expression ISO Rifampin results in increased expression of SLC5A12 mRNA CTD PMID:27199754 NCBI chr 2:110,427,644...110,479,690
Ensembl chr 2:110,427,643...110,478,124
JBrowse link
G Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 increases expression ISO Rifampin results in increased expression of SLC6A12 mRNA CTD PMID:27199754 NCBI chr 6:121,319,533...121,342,732
Ensembl chr 6:121,320,035...121,342,734
JBrowse link
G Slc6a20b solute carrier family 6 (neurotransmitter transporter), member 20B increases expression ISO Rifampin results in increased expression of SLC6A20 mRNA CTD PMID:27199754 NCBI chr 9:123,422,888...123,461,603
Ensembl chr 9:123,419,865...123,461,630
JBrowse link
G Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 increases expression ISO Rifampin results in increased expression of SLC6A9 mRNA CTD PMID:27199754 NCBI chr 4:117,692,240...117,726,502
Ensembl chr 4:117,691,703...117,732,395
JBrowse link
G Slc7a11 solute carrier family 7 (cationic amino acid transporter, y+ system), member 11 multiple interactions ISO [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 mRNA; [Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein; HIF1A protein affects the reaction [[Isoniazid co-treated with Rifampin co-treated with Pyrazinamide co-treated with Ethambutol] results in decreased expression of SLC7A11 protein] CTD PMID:36878459 NCBI chr 3:50,319,385...50,403,947
Ensembl chr 3:49,846,975...50,398,063
JBrowse link
G Slc9a8 solute carrier family 9 (sodium/hydrogen exchanger), member 8 increases expression ISO Rifampin results in increased expression of SLC9A8 mRNA CTD PMID:27199754 NCBI chr 2:167,261,678...167,318,920
Ensembl chr 2:167,263,632...167,318,920
JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 multiple interactions EXP Rifampin inhibits the reaction [SLCO1A1 protein results in increased uptake of epyrifenacil metabolite] CTD PMID:34619012 NCBI chr 6:141,853,007...141,892,688
Ensembl chr 6:141,853,008...141,892,688
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 multiple interactions
decreases activity
ISO
EXP
Rifampin inhibits the reaction [SLCO1A4 protein results in increased uptake of Digoxin]
Rifampin inhibits the reaction [SLCO1A4 protein results in increased uptake of epyrifenacil metabolite]
Rifampin results in decreased activity of SLCO1A4 protein
CTD PMID:11883641 PMID:34619012 NCBI chr 6:141,751,164...141,802,011
Ensembl chr 6:141,751,166...141,801,925
JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 multiple interactions
decreases activity
decreases expression
ISO
EXP
Rifampin inhibits the reaction [SLCO1B3 protein results in increased import of cyanoginosin LR]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of epyrifenacil metabolite]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of estradiol-17 beta-glucuronide]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of fexofenadine]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Hydroxyurea]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Sulfobromophthalein]; Rifampin inhibits the reaction [SLCO1B3 protein results in increased uptake of Ursodeoxycholic Acid metabolite]
Rifampin inhibits the reaction [SLCO1B2 protein results in increased uptake of epyrifenacil metabolite]
Rifampin results in decreased activity of SLCO1B3 protein
Rifampin results in decreased expression of SLCO1B3 mRNA
CTD PMID:17369605 PMID:18180276 PMID:21256917 PMID:21430235 PMID:27199754 More... NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372
JBrowse link
G Slco1c1 solute carrier organic anion transporter family, member 1c1 multiple interactions
decreases activity
ISO [Rifampin results in decreased activity of SLCO1B1 protein] which results in decreased uptake of Methotrexate CTD PMID:32259555 NCBI chr 6:141,470,080...141,515,903
Ensembl chr 6:141,470,094...141,515,903
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 multiple interactions ISO Rifampin inhibits the reaction [decitabine results in increased expression of SLCO2A1 mRNA] CTD PMID:23137910 NCBI chr 9:102,885,686...102,973,201
Ensembl chr 9:102,865,911...102,973,201
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions
increases expression
ISO Rifampin inhibits the reaction [SLCO2B1 protein results in increased uptake of Mesalamine]; Rifampin inhibits the reaction [SLCO2B1 protein results in increased uptake of Sulfobromophthalein]
Rifampin results in increased expression of SLCO2B1 mRNA
CTD PMID:21430235 PMID:27199754 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547
JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 increases expression ISO Rifampin results in increased expression of SLCO4C1 mRNA CTD PMID:27199754 NCBI chr 1:96,744,918...96,800,027
Ensembl chr 1:96,743,995...96,799,896
JBrowse link
G Smad9 SMAD family member 9 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SMAD9 mRNA CTD PMID:21127053 NCBI chr 3:54,662,873...54,709,162
Ensembl chr 3:54,663,003...54,708,678
JBrowse link
G Snca synuclein, alpha multiple interactions
increases sumoylation
ISO Rifampin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein modified form]; UBE2I affects the reaction [Rifampin results in increased sumoylation of SNCA protein] CTD PMID:17280646 PMID:28132806 NCBI chr 6:60,708,557...60,806,839
Ensembl chr 6:60,708,559...60,806,839
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of SOCS3 mRNA CTD PMID:21127053 NCBI chr11:117,856,905...117,860,192
Ensembl chr11:117,856,905...117,860,873
JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 decreases expression ISO Rifampin results in decreased expression of SORBS1 mRNA CTD PMID:24552687 NCBI chr19:40,280,484...40,502,399
Ensembl chr19:40,283,197...40,502,223
JBrowse link
G Sptb spectrin beta, erythrocytic increases expression ISO Rifampin results in increased expression of SPTB mRNA CTD PMID:24552687 NCBI chr12:76,627,262...76,757,321
Ensembl chr12:76,627,262...76,757,321
JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Rifampin results in increased expression of SQSTM1 protein CTD PMID:29908302 NCBI chr11:50,090,979...50,105,303
Ensembl chr11:50,090,193...50,101,654
JBrowse link
G Src Rous sarcoma oncogene multiple interactions ISO [SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA; allyl isothiocyanate inhibits the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]; allyl isothiocyanate inhibits the reaction [NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA]]; NR1I2 protein promotes the reaction [[SRC protein co-treated with Rifampin] results in increased expression of CYP3A4 mRNA] CTD PMID:25069801 NCBI chr 2:157,265,828...157,313,758
Ensembl chr 2:157,260,364...157,313,782
JBrowse link
G Stat5a signal transducer and activator of transcription 5A multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in decreased expression of STAT5A mRNA CTD PMID:21127053 NCBI chr11:100,750,177...100,775,995
Ensembl chr11:100,750,177...100,775,995
JBrowse link
G Stk39 serine/threonine kinase 39 increases expression ISO Rifampin results in increased expression of STK39 mRNA CTD PMID:24552687 NCBI chr 2:68,040,789...68,302,381
Ensembl chr 2:68,040,789...68,302,612
JBrowse link
G Sult1e1 sulfotransferase family 1E, member 1 multiple interactions ISO [NR1I2 protein co-treated with Rifampin] results in decreased expression of SULT1E1 mRNA; [Rifampin results in increased activity of NR1I2 protein] inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer]; Rifampin inhibits the reaction [HNF4A protein binds to SULT1E1 enhancer] CTD PMID:21764778 NCBI chr 5:87,723,827...87,739,470
Ensembl chr 5:87,723,828...87,739,453
JBrowse link
G Sult2a1 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 multiple interactions EXP
ISO
[Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter]] which results in increased expression of SULT2A1 mRNA; Rifampin promotes the reaction [[NR1I2 protein co-treated with RXRA protein] binds to SULT2A1 promoter] CTD PMID:12370413 NCBI chr 7:13,530,171...13,571,335
Ensembl chr 7:13,530,171...13,571,334
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 increases expression ISO Rifampin results in increased expression of SUMO1 protein CTD PMID:28132806 NCBI chr 1:59,678,593...59,709,993
Ensembl chr 1:59,625,717...59,709,993
JBrowse link
G Sumo3 small ubiquitin-like modifier 3 multiple interactions ISO Rifampin inhibits the reaction [trichostatin A inhibits the reaction [[PIAS1 co-treated with SUMO3] inhibits the reaction [NCOR2 protein promotes the reaction [NR1I2 protein binds to HDAC3 protein]]]] CTD PMID:26883953 NCBI chr10:77,441,931...77,454,165
Ensembl chr10:77,441,931...77,454,165
JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 decreases expression ISO Rifampin results in decreased expression of SUN1 mRNA CTD PMID:24552687 NCBI chr 5:139,186,313...139,235,594
Ensembl chr 5:139,186,392...139,235,595
JBrowse link
G Tbata thymus, brain and testes associated decreases expression ISO Rifampin results in decreased expression of TBATA mRNA CTD PMID:24552687 NCBI chr10:61,007,743...61,024,620
Ensembl chr10:61,007,733...61,024,620
JBrowse link
G Tfec transcription factor EC increases expression ISO Rifampin results in increased expression of TFEC mRNA CTD PMID:24552687 NCBI chr 6:16,830,926...16,898,463
Ensembl chr 6:16,833,372...16,898,440
JBrowse link
G Thsd4 thrombospondin, type I, domain containing 4 increases expression ISO Rifampin results in increased expression of THSD4 mRNA CTD PMID:24552687 NCBI chr 9:59,874,214...60,429,394
Ensembl chr 9:59,874,214...60,429,329
JBrowse link
G Tjp1 tight junction protein 1 affects localization
decreases expression
EXP Rifampin affects the localization of TJP1 protein
Rifampin results in decreased expression of TJP1 mRNA
CTD PMID:19577586 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tjp2 tight junction protein 2 decreases expression EXP Rifampin results in decreased expression of TJP2 mRNA CTD PMID:19577586 NCBI chr19:24,071,860...24,202,492
Ensembl chr19:24,071,869...24,202,394
JBrowse link
G Tlr1 toll-like receptor 1 increases expression ISO Rifampin results in increased expression of TLR1 mRNA CTD PMID:24552687 NCBI chr 5:65,082,023...65,090,945
Ensembl chr 5:65,082,022...65,090,906
JBrowse link
G Tmem120b transmembrane protein 120B decreases expression ISO Rifampin results in decreased expression of TMEM120B mRNA CTD PMID:24552687 NCBI chr 5:123,214,329...123,256,272
Ensembl chr 5:123,206,478...123,255,812
JBrowse link
G Tmem145 transmembrane protein 145 increases expression ISO Rifampin results in increased expression of TMEM145 mRNA CTD PMID:24552687 NCBI chr 7:25,004,981...25,015,621
Ensembl chr 7:25,005,531...25,015,620
JBrowse link
G Tmem88 transmembrane protein 88 increases expression ISO Rifampin results in increased expression of TMEM88 mRNA CTD PMID:24552687 NCBI chr11:69,287,342...69,289,060
Ensembl chr11:69,287,345...69,289,060
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Rifampin results in decreased expression of TNF protein CTD PMID:21357946 NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b multiple interactions EXP [Rifampin co-treated with Cobicistat] results in increased expression of TNFRSF10B mRNA CTD PMID:33629115 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TNFSF10 mRNA CTD PMID:21224054 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
G Tradd TNFRSF1A-associated via death domain multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of TRADD mRNA CTD PMID:21224054 NCBI chr 8:105,985,207...105,991,226
Ensembl chr 8:105,984,918...105,991,241
JBrowse link
G Trim43a tripartite motif-containing 43A decreases expression ISO Rifampin results in decreased expression of TRIM51 mRNA CTD PMID:24552687 NCBI chr 9:88,462,944...88,470,877
Ensembl chr 9:88,462,944...88,470,872
JBrowse link
G Tsku tsukushi, small leucine rich proteoglycan increases expression ISO Rifampin results in increased expression of TSKU mRNA CTD PMID:24552687 PMID:27177772 NCBI chr 7:97,999,875...98,010,602
Ensembl chr 7:97,999,875...98,010,535
JBrowse link
G Ube2i ubiquitin-conjugating enzyme E2I multiple interactions ISO UBE2I affects the reaction [Rifampin results in increased sumoylation of SNCA protein] CTD PMID:28132806 NCBI chr17:25,479,484...25,494,965
Ensembl chr17:25,479,482...25,493,856
JBrowse link
G Ugdh UDP-glucose dehydrogenase multiple interactions
increases expression
ISO [Rifampin co-treated with PPARA protein co-treated with RXRA protein] results in decreased expression of UGDH mRNA
Rifampin results in increased expression of UGDH mRNA
CTD PMID:16292757 NCBI chr 5:65,570,550...65,593,185
Ensembl chr 5:65,570,564...65,593,292
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 affects expression
increases expression
multiple interactions
ISO Rifampin affects the expression of UGT1A1 mRNA
Rifampin results in increased expression of UGT1A1 mRNA
[Rifampin co-treated with NR1I2 protein] results in increased expression of UGT1A1 mRNA; [Tetrachlorodibenzodioxin co-treated with Rifampin] results in increased expression of UGT1A1 mRNA
CTD PMID:15104253 PMID:15771232 PMID:15849716 PMID:18098064 PMID:22126990 More... NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719
JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 multiple interactions
increases expression
ISO pimecrolimus inhibits the reaction [Rifampin results in increased expression of UGT1A3 mRNA] CTD PMID:25313206 PMID:29356861 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719
JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B increases expression ISO Rifampin results in increased expression of UGT1A6 mRNA CTD PMID:18094037 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases expression ISO Rifampin results in increased expression of UGT1A9 mRNA; Rifampin results in increased expression of UGT1A9 protein CTD PMID:25070100 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719
JBrowse link
G Uhrf2 ubiquitin-like, containing PHD and RING finger domains 2 decreases expression ISO Rifampin results in decreased expression of UHRF2 mRNA CTD PMID:24552687 NCBI chr19:30,007,920...30,071,126
Ensembl chr19:30,007,913...30,071,122
JBrowse link
G Ung uracil DNA glycosylase multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of UNG mRNA CTD PMID:21224054 NCBI chr 5:114,268,427...114,277,382
Ensembl chr 5:114,268,447...114,277,384
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Rifampin results in increased expression of VEGFA protein CTD PMID:25051504 NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfd vascular endothelial growth factor D multiple interactions ISO [Rifampin co-treated with NR1I2 protein] results in increased expression of VEGFD mRNA CTD PMID:21127053 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646
JBrowse link
G Vkorc1 vitamin K epoxide reductase complex, subunit 1 affects response to substance ISO VKORC1 alternative form affects the susceptibility to Rifampin CTD PMID:36789833 NCBI chr 7:127,492,235...127,494,833
Ensembl chr 7:127,485,399...127,494,626
Ensembl chr 7:127,485,399...127,494,626
JBrowse link
G Vwa1 von Willebrand factor A domain containing 1 decreases expression ISO Rifampin results in decreased expression of VWA1 mRNA CTD PMID:24552687 NCBI chr 4:155,852,952...155,859,042
Ensembl chr 4:155,852,606...155,859,155
JBrowse link
G Xiap X-linked inhibitor of apoptosis increases expression ISO Rifampin results in increased expression of XIAP protein CTD PMID:12645856 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
G Xrcc4 X-ray repair complementing defective repair in Chinese hamster cells 4 multiple interactions EXP [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of XRCC4 mRNA CTD PMID:21224054 NCBI chr13:89,997,033...90,237,727
Ensembl chr13:89,922,146...90,237,727
JBrowse link
G Zcchc13 zinc finger, CCHC domain containing 13 decreases expression ISO Rifampin results in decreased expression of ZCCHC13 mRNA CTD PMID:24552687 NCBI chr  X:102,674,187...102,675,277
Ensembl chr  X:102,674,192...102,675,276
JBrowse link
G Zfp11 zinc finger protein 11 decreases expression ISO Rifampin results in decreased expression of ZNF546 mRNA CTD PMID:24552687 NCBI chr 5:129,731,659...129,747,152
Ensembl chr 5:129,731,657...129,747,163
JBrowse link
G Zfp451 zinc finger protein 451 decreases expression ISO Rifampin results in decreased expression of ZNF451 mRNA CTD PMID:24552687 NCBI chr 1:33,800,622...33,854,683
Ensembl chr 1:33,800,626...33,853,676
JBrowse link
G Zfp46 zinc finger protein 46 decreases expression ISO Rifampin results in decreased expression of ZNF436 mRNA CTD PMID:24552687 NCBI chr 4:136,011,479...136,021,163
Ensembl chr 4:136,011,994...136,021,253
JBrowse link
G Zfp462 zinc finger protein 462 decreases expression ISO Rifampin results in decreased expression of ZNF462 mRNA CTD PMID:24552687 NCBI chr 4:54,942,038...55,083,563
Ensembl chr 4:54,945,048...55,083,563
JBrowse link
rifapentine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadac arylacetamide deacetylase multiple interactions
decreases acetylation
ISO AADAC mRNA affects the reaction [rifapentine results in increased expression of CYP3A4 mRNA]; bis(4-nitrophenyl)phosphate inhibits the reaction [AADAC protein results in decreased acetylation of rifapentine]; Isoflurophate inhibits the reaction [AADAC protein results in decreased acetylation of rifapentine]; Phenylmethylsulfonyl Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of rifapentine]; Physostigmine inhibits the reaction [AADAC protein results in decreased acetylation of rifapentine]; Sodium Fluoride inhibits the reaction [AADAC protein results in decreased acetylation of rifapentine] CTD PMID:21856291 NCBI chr 3:59,939,209...59,947,578
Ensembl chr 3:59,933,138...59,947,581
JBrowse link
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases activity ISO rifapentine results in decreased activity of ABCB11 protein CTD PMID:23956101 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958
JBrowse link
G Ar androgen receptor multiple interactions ISO rifapentine binds to and results in decreased activity of AR protein CTD PMID:25752796 NCBI chr  X:97,192,363...97,366,824
Ensembl chr  X:97,192,375...97,366,821
JBrowse link
G Esr2 estrogen receptor 2 (beta) multiple interactions ISO rifapentine binds to and results in decreased activity of ESR2 protein CTD PMID:25752796 NCBI chr12:76,167,193...76,224,033
Ensembl chr12:76,167,193...76,224,033
JBrowse link
thalidomide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aadat aminoadipate aminotransferase decreases expression EXP Thalidomide results in decreased expression of AADAT mRNA CTD PMID:26217789 NCBI chr 8:60,958,877...60,998,711
Ensembl chr 8:60,958,966...60,998,711
JBrowse link
G Abca1 ATP-binding cassette, sub-family A member 1 increases response to substance ISO ABCA1 gene SNP results in increased susceptibility to Thalidomide CTD PMID:21245421 NCBI chr 4:53,030,789...53,159,988
Ensembl chr 4:53,030,787...53,159,895
JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A decreases expression
decreases activity
ISO Thalidomide results in decreased expression of ABCB1 mRNA; Thalidomide results in decreased expression of ABCB1 protein
Thalidomide results in decreased activity of ABCB1 protein
CTD PMID:15920492 PMID:19840843 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B increases expression
increases activity
ISO Thalidomide results in increased expression of ABCB1B protein
Thalidomide results in increased activity of ABCB1B protein
CTD PMID:19840843 NCBI chr 5:8,848,147...8,916,314
Ensembl chr 5:8,848,147...8,916,315
JBrowse link
G Acat3 acetyl-Coenzyme A acetyltransferase 3 decreases expression EXP Thalidomide results in decreased expression of ACAT3 mRNA CTD PMID:26217789 NCBI chr17:13,142,720...13,159,482
Ensembl chr17:13,142,700...13,159,487
JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO [Thalidomide co-treated with Dexamethasone] results in decreased expression of ACP5 protein CTD PMID:16079895 NCBI chr 9:22,038,023...22,047,042
Ensembl chr 9:22,038,023...22,047,007
JBrowse link
G Acta2 actin alpha 2, smooth muscle, aorta multiple interactions
decreases expression
ISO [Thalidomide co-treated with Dimethylnitrosamine] results in decreased expression of ACTA2 protein; Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]; Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 mRNA]; Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of ACTA2 protein]; Thalidomide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
Thalidomide results in decreased expression of ACTA2 protein
CTD PMID:16604421 PMID:16943688 PMID:17030452 PMID:17174718 NCBI chr19:34,217,736...34,232,985
Ensembl chr19:34,218,490...34,232,990
JBrowse link
G Actn2 actinin alpha 2 decreases expression EXP Thalidomide results in decreased expression of ACTN2 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr13:12,284,312...12,355,613
Ensembl chr13:12,284,312...12,355,641
JBrowse link
G Actr6 ARP6 actin-related protein 6 decreases expression EXP Thalidomide results in decreased expression of ACTR6 mRNA CTD PMID:26217789 NCBI chr10:89,547,828...89,568,184
Ensembl chr10:89,547,833...89,568,157
JBrowse link
G Adam34 a disintegrin and metallopeptidase domain 34 increases expression EXP Thalidomide results in increased expression of ADAM34 mRNA CTD PMID:26217789 NCBI chr 8:44,103,346...44,118,597
Ensembl chr 8:44,103,346...44,163,086
JBrowse link
G Adam4 a disintegrin and metallopeptidase domain 4 decreases expression EXP Thalidomide results in decreased expression of ADAM4 mRNA CTD PMID:26217789 NCBI chr12:81,466,217...81,468,813
Ensembl chr12:81,466,217...81,468,720
JBrowse link
G Adss1 adenylosuccinate synthase 1 decreases expression EXP Thalidomide results in decreased expression of ADSS1 mRNA CTD PMID:26217789 NCBI chr12:112,586,481...112,607,789
Ensembl chr12:112,586,479...112,607,794
JBrowse link
G Aff2 AF4/FMR2 family, member 2 decreases expression EXP Thalidomide results in decreased expression of AFF2 mRNA CTD PMID:26217789 NCBI chr  X:68,403,796...68,915,660
Ensembl chr  X:68,403,900...68,911,643
JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases phosphorylation
increases phosphorylation
decreases activity
ISO Thalidomide analog results in decreased phosphorylation of AKT1 protein
Thalidomide analog results in increased phosphorylation of AKT1 protein
Thalidomide results in decreased activity of AKT1 protein
CTD PMID:15067094 PMID:15858615 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318
JBrowse link
G Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 decreases expression ISO Thalidomide results in decreased expression of ALDH1A2 mRNA CTD PMID:31711903 NCBI chr 9:71,123,071...71,203,525
Ensembl chr 9:71,123,071...71,203,525
JBrowse link
G Alpi alkaline phosphatase, intestinal increases expression EXP Thalidomide results in increased expression of ALPI mRNA CTD PMID:26217789 NCBI chr 1:87,025,724...87,029,328
Ensembl chr 1:87,025,724...87,029,328
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression EXP Thalidomide results in decreased expression of AMACR mRNA CTD PMID:26217789 NCBI chr15:10,981,875...10,995,693
Ensembl chr15:10,981,842...10,996,712
JBrowse link
G Angpt2 angiopoietin 2 affects expression ISO Thalidomide affects the expression of ANGPT2 mRNA CTD PMID:15939924 NCBI chr 8:18,740,279...18,791,578
Ensembl chr 8:18,740,279...18,791,578
JBrowse link
G Ankrd37 ankyrin repeat domain 37 decreases expression EXP Thalidomide results in decreased expression of ANKRD37 mRNA CTD PMID:26217789 NCBI chr 8:46,449,945...46,452,904
Ensembl chr 8:46,449,939...46,458,744
JBrowse link
G Anxa2 annexin A2 decreases expression ISO Thalidomide results in decreased expression of ANXA2 mRNA; Thalidomide results in decreased expression of ANXA2 protein CTD PMID:19954599 NCBI chr 9:69,360,978...69,399,074
Ensembl chr 9:69,360,902...69,399,077
JBrowse link
G Apip APAF1 interacting protein decreases expression EXP Thalidomide results in decreased expression of APIP mRNA CTD PMID:26217789 NCBI chr 2:102,904,020...102,922,994
Ensembl chr 2:102,904,020...102,922,989
JBrowse link
G Apln apelin decreases expression EXP Thalidomide results in decreased expression of APLN mRNA CTD PMID:26217789 NCBI chr  X:47,114,023...47,123,730
Ensembl chr  X:47,114,023...47,123,730
JBrowse link
G Aqp4 aquaporin 4 increases expression EXP Thalidomide results in increased expression of AQP4 mRNA CTD PMID:26217789 NCBI chr18:15,522,451...15,544,039
Ensembl chr18:15,522,553...15,544,039
JBrowse link
G Aqp5 aquaporin 5 increases expression EXP Thalidomide results in increased expression of AQP5 mRNA CTD PMID:26217789 NCBI chr15:99,488,909...99,492,710
Ensembl chr15:99,488,663...99,492,710
JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha increases expression EXP Thalidomide results in increased expression of ARHGDIA mRNA CTD PMID:26217789 NCBI chr11:120,468,925...120,472,450
Ensembl chr11:120,468,930...120,472,450
JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 decreases expression EXP Thalidomide results in decreased expression of ARPC4 mRNA CTD PMID:26217789 NCBI chr 6:113,355,074...113,367,408
Ensembl chr 6:113,355,076...113,367,409
JBrowse link
G Arx aristaless related homeobox increases expression EXP Thalidomide results in increased expression of ARX mRNA CTD PMID:26217789 NCBI chr  X:92,330,113...92,341,963
Ensembl chr  X:92,330,051...92,341,963
JBrowse link
G Arxes1 adipocyte-related X-chromosome expressed sequence 1 decreases expression EXP Thalidomide results in decreased expression of ARXES1 mRNA CTD PMID:26217789 NCBI chr  X:134,934,116...134,935,695
Ensembl chr  X:134,934,116...134,935,695
JBrowse link
G Asb12 ankyrin repeat and SOCS box-containing 12 decreases expression EXP Thalidomide results in decreased expression of ASB12 mRNA CTD PMID:26217789 NCBI chr  X:94,513,125...94,601,610
Ensembl chr  X:94,513,807...94,601,593
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Thalidomide analog results in increased expression of ATF3 mRNA CTD PMID:20525221 NCBI chr 1:190,902,493...190,915,530
Ensembl chr 1:190,902,493...190,950,236
JBrowse link
G Aurka aurora kinase A multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of AURKA mRNA CTD PMID:18720364 NCBI chr 2:172,198,116...172,212,825
Ensembl chr 2:172,198,110...172,212,455
JBrowse link
G Bax BCL2-associated X protein increases expression ISO Thalidomide results in increased expression of BAX mRNA CTD PMID:18291259 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322
JBrowse link
G Bcap29 B cell receptor associated protein 29 decreases expression EXP Thalidomide results in decreased expression of BCAP29 mRNA CTD PMID:26217789 NCBI chr12:31,645,353...31,684,657
Ensembl chr12:31,640,966...31,684,657
JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions
decreases expression
ISO [oblimersen co-treated with Thalidomide co-treated with Dexamethasone] results in decreased expression of BCL2 mRNA; [oblimersen co-treated with Thalidomide co-treated with Dexamethasone] results in decreased expression of BCL2 protein
Thalidomide results in decreased expression of BCL2 protein
CTD PMID:15867202 PMID:15982930 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004
JBrowse link
G Bcl2l1 BCL2-like 1 decreases expression ISO Thalidomide results in decreased expression of BCL2L1 protein CTD PMID:15986355 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648
JBrowse link
G Bdkrb1 bradykinin receptor, beta 1 multiple interactions EXP Thalidomide inhibits the reaction [bradykinin, des-Arg(9)- results in increased expression of BDKRB1 protein] CTD PMID:16039549 NCBI chr12:105,570,350...105,571,770
Ensembl chr12:105,569,344...105,571,687
JBrowse link
G Becn1 beclin 1, autophagy related multiple interactions ISO Thalidomide promotes the reaction [temozolomide results in increased expression of BECN1 protein] CTD PMID:19567134 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112
JBrowse link
G Bnipl BCL2/adenovirus E1B 19kD interacting protein like increases expression EXP Thalidomide results in increased expression of BNIPL mRNA CTD PMID:26217789 NCBI chr 3:95,148,587...95,158,504
Ensembl chr 3:95,148,582...95,158,504
JBrowse link
G Bod1 biorientation of chromosomes in cell division 1 decreases expression EXP Thalidomide results in decreased expression of BOD1 mRNA CTD PMID:26217789 NCBI chr11:31,615,150...31,621,862
Ensembl chr11:31,615,181...31,621,885
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 decreases expression EXP Thalidomide results in decreased expression of BST2 mRNA CTD PMID:26217789 NCBI chr 8:71,986,899...71,990,116
Ensembl chr 8:71,986,899...71,990,100
JBrowse link
G Btnl5-ps butyrophilin-like 5, pseudogene decreases expression EXP Thalidomide results in decreased expression of BTNL5-PS mRNA CTD PMID:26217789 NCBI chr17:34,706,379...34,716,403
Ensembl chr17:34,707,044...34,714,978
JBrowse link
G Bub1b BUB1B, mitotic checkpoint serine/threonine kinase multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of BUB1B mRNA CTD PMID:18720364 NCBI chr 2:118,428,684...118,472,073
Ensembl chr 2:118,428,692...118,472,072
JBrowse link
G C3 complement component 3 decreases expression ISO Thalidomide results in decreased expression of C3 protein CTD PMID:2985516 NCBI chr17:57,510,967...57,535,136
Ensembl chr17:57,510,970...57,535,136
JBrowse link
G Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit decreases expression EXP Thalidomide results in decreased expression of CACNA1C mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 6:118,564,201...119,174,345
Ensembl chr 6:118,564,201...119,173,851
JBrowse link
G Cacnb4 calcium channel, voltage-dependent, beta 4 subunit decreases expression ISO Thalidomide results in decreased expression of CACNB4 mRNA CTD PMID:32756504 NCBI chr 2:52,318,332...52,566,816
Ensembl chr 2:52,318,337...52,566,843
JBrowse link
G Calb1 calbindin 1 decreases expression ISO Thalidomide results in decreased expression of CALB1 mRNA CTD PMID:24154490 NCBI chr 4:15,881,264...15,906,709
Ensembl chr 4:15,881,264...15,908,064
JBrowse link
G Casp3 caspase 3 decreases activity
increases activity
increases expression
ISO Thalidomide results in decreased activity of CASP3 protein
Thalidomide results in increased activity of CASP3 protein
Thalidomide results in increased expression of CASP3 mRNA
CTD PMID:14682394 PMID:15067094 PMID:18291259 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724
JBrowse link
G Casp8 caspase 8 increases cleavage
decreases expression
ISO
EXP
Thalidomide analog results in increased cleavage of CASP8 protein
Thalidomide results in decreased expression of CASP8 mRNA
CTD PMID:15858615 PMID:26217789 NCBI chr 1:58,834,553...58,886,663
Ensembl chr 1:58,834,533...58,886,662
JBrowse link
G Casp9 caspase 9 decreases activity ISO Thalidomide results in decreased activity of CASP9 protein CTD PMID:15067094 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 decreases expression EXP Thalidomide results in decreased expression of CASTOR1 mRNA CTD PMID:26217789 NCBI chr11:4,167,401...4,172,409
Ensembl chr11:4,168,225...4,172,409
JBrowse link
G Cat catalase multiple interactions ISO CAT protein inhibits the reaction [Thalidomide results in decreased activity of MYB protein] CTD PMID:16616857 NCBI chr 2:103,284,249...103,315,498
Ensembl chr 2:103,284,194...103,315,505
JBrowse link
G Cbr1 carbonyl reductase 1 decreases expression EXP Thalidomide results in decreased expression of CBR1 mRNA CTD PMID:26217789 NCBI chr16:93,404,752...93,407,226
Ensembl chr16:93,402,741...93,407,393
JBrowse link
G Ccdc141 coiled-coil domain containing 141 decreases expression EXP Thalidomide results in decreased expression of CCDC141 mRNA CTD PMID:26217789 NCBI chr 2:76,840,246...77,006,424
Ensembl chr 2:76,840,246...77,000,980
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO Thalidomide analog results in decreased expression of CCL2 mRNA CTD PMID:20525221 NCBI chr11:81,926,403...81,928,278
Ensembl chr11:81,926,397...81,928,279
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression ISO Thalidomide results in increased expression of CCL3 mRNA CTD PMID:16549389 NCBI chr11:83,538,669...83,540,204
Ensembl chr11:83,538,670...83,540,181
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CCNA2 mRNA CTD PMID:18720364 NCBI chr 3:36,619,014...36,627,187
Ensembl chr 3:36,619,014...36,626,299
JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CCNB1 mRNA CTD PMID:18720364 NCBI chr13:100,915,247...100,922,994
Ensembl chr13:100,915,158...100,923,078
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Thalidomide analog results in decreased expression of CCND1 mRNA CTD PMID:20525221 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662
JBrowse link
G Ccno cyclin O increases expression EXP Thalidomide results in increased expression of CCNO mRNA CTD PMID:26217789 NCBI chr13:113,124,363...113,127,313
Ensembl chr13:113,124,336...113,127,311
JBrowse link
G Cd24a CD24a antigen affects expression EXP Thalidomide affects the expression of CD24A mRNA CTD PMID:26006729 NCBI chr10:43,454,433...43,460,261
Ensembl chr10:43,454,280...43,460,261
JBrowse link
G Cd274 CD274 antigen decreases expression
multiple interactions
ISO Thalidomide results in decreased expression of CD274 protein
FGD5-AS1 inhibits the reaction [Thalidomide results in decreased expression of CD274 protein]
CTD PMID:34520751 NCBI chr19:29,339,428...29,365,495
Ensembl chr19:29,344,855...29,365,495
JBrowse link
G Cdc20 cell division cycle 20 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CDC20 mRNA CTD PMID:18720364 NCBI chr 4:118,290,098...118,294,540
Ensembl chr 4:118,290,098...118,294,549
JBrowse link
G Cdc42ep5 CDC42 effector protein 5 decreases expression EXP Thalidomide results in decreased expression of CDC42EP5 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 7:4,154,259...4,167,830
Ensembl chr 7:4,154,259...4,167,859
JBrowse link
G Cdh1 cadherin 1 increases expression
multiple interactions
ISO Thalidomide results in increased expression of CDH1 protein
FGD5-AS1 inhibits the reaction [Thalidomide results in increased expression of CDH1 protein]
CTD PMID:34520751 NCBI chr 8:107,329,982...107,396,879
Ensembl chr 8:107,329,983...107,396,878
JBrowse link
G Cdh10 cadherin 10 decreases expression EXP Thalidomide results in decreased expression of CDH10 mRNA CTD PMID:26217789 NCBI chr15:18,818,763...19,014,883
Ensembl chr15:18,819,033...19,014,322
JBrowse link
G Cdh2 cadherin 2 multiple interactions
decreases expression
ISO FGD5-AS1 inhibits the reaction [Thalidomide results in decreased expression of CDH2 protein] CTD PMID:34520751 NCBI chr18:16,721,934...16,942,303
Ensembl chr18:16,721,934...16,942,303
JBrowse link
G Cdh6 cadherin 6 increases expression ISO Thalidomide results in increased expression of CDH6 mRNA CTD PMID:32756504 NCBI chr15:13,028,785...13,176,493
Ensembl chr15:13,028,787...13,173,761
JBrowse link
G Cdk1 cyclin dependent kinase 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CDK1 mRNA CTD PMID:18720364 NCBI chr10:69,170,976...69,188,742
Ensembl chr10:69,170,976...69,188,768
JBrowse link
G Cenpa centromere protein A multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CENPA mRNA CTD PMID:18720364 NCBI chr 5:30,824,214...30,832,181
Ensembl chr 5:30,824,121...30,832,174
JBrowse link
G Cenpf centromere protein F multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of CENPF mRNA CTD PMID:18720364 NCBI chr 1:189,372,803...189,420,302
Ensembl chr 1:189,372,803...189,420,283
JBrowse link
G Cer1 cerberus 1, DAN family BMP antagonist decreases expression EXP Thalidomide results in decreased expression of CER1 mRNA CTD PMID:26217789 NCBI chr 4:82,799,988...82,803,388
Ensembl chr 4:82,799,988...82,803,385
JBrowse link
G Cfc1 cryptic, EGF-CFC family member 1 decreases expression EXP Thalidomide results in decreased expression of CFC1 mRNA CTD PMID:26217789 NCBI chr 1:34,574,729...34,583,392
Ensembl chr 1:34,574,729...34,583,394
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO Thalidomide results in decreased expression of CFLAR protein CTD PMID:15986355 NCBI chr 1:58,750,353...58,798,043
Ensembl chr 1:58,750,667...58,798,043
JBrowse link
G Chuk conserved helix-loop-helix ubiquitous kinase multiple interactions ISO Thalidomide inhibits the reaction [TNF protein results in increased expression of CHUK protein] CTD PMID:16604421 NCBI chr19:44,061,773...44,095,940
Ensembl chr19:44,061,774...44,095,919
JBrowse link
G Churc1 churchill domain containing 1 decreases expression EXP Thalidomide results in decreased expression of CHURC1 mRNA CTD PMID:26217789 NCBI chr12:76,812,312...76,829,954
Ensembl chr12:76,812,312...76,829,954
JBrowse link
G Cldn4 claudin 4 increases expression EXP Thalidomide results in increased expression of CLDN4 mRNA CTD PMID:26217789 NCBI chr 5:134,973,977...134,975,788
Ensembl chr 5:134,973,973...134,975,788
JBrowse link
G Cldnd1 claudin domain containing 1 decreases expression EXP Thalidomide results in decreased expression of CLDND1 mRNA CTD PMID:26217789 NCBI chr16:58,548,269...58,554,610
Ensembl chr16:58,548,273...58,554,614
JBrowse link
G Clec9a C-type lectin domain family 9, member a decreases expression EXP Thalidomide results in decreased expression of CLEC9A mRNA CTD PMID:26217789 NCBI chr 6:129,385,825...129,401,727
Ensembl chr 6:129,385,825...129,401,726
JBrowse link
G Col1a1 collagen, type I, alpha 1 multiple interactions ISO Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of COL1A1 protein] CTD PMID:26221080 NCBI chr11:94,827,050...94,843,868
Ensembl chr11:94,827,050...94,843,868
JBrowse link
G Col1a2 collagen, type I, alpha 2 multiple interactions ISO Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of COL1A2 mRNA]; Thalidomide inhibits the reaction [TNF protein results in increased expression of COL1A2 mRNA] CTD PMID:16604421 NCBI chr 6:4,505,618...4,541,543
Ensembl chr 6:4,504,814...4,541,544
JBrowse link
G Cplx3 complexin 3 decreases expression ISO Thalidomide results in decreased expression of CPLX3 mRNA CTD PMID:32756504 NCBI chr 9:57,507,275...57,513,564
Ensembl chr 9:57,507,275...57,513,564
JBrowse link
G Crbn cereblon multiple interactions
affects response to substance
affects binding
ISO
EXP
Thalidomide inhibits the reaction [CRBN protein binds to and results in increased ubiquitination of and results in increased degradation of MEIS2 protein]
CRBN gene SNP affects the susceptibility to Thalidomide
Thalidomide binds to [SALL4 protein binds to CRBN protein]; Thalidomide binds to CRBN protein
Thalidomide binds to [CRBN protein binds to DDB1 protein]
CTD PMID:25043012 PMID:25108355 PMID:27751757 PMID:30067223 NCBI chr 6:106,755,205...106,777,060
Ensembl chr 6:106,757,162...106,777,038
JBrowse link
G Creb5 cAMP responsive element binding protein 5 decreases expression ISO Thalidomide results in decreased expression of CREB5 mRNA CTD PMID:32756504 NCBI chr 6:53,264,154...53,677,349
Ensembl chr 6:53,264,255...53,677,361
JBrowse link
G Crebrf CREB3 regulatory factor increases expression ISO Thalidomide analog results in increased expression of CREBRF mRNA CTD PMID:20525221 NCBI chr17:26,918,716...26,995,611
Ensembl chr17:26,934,624...26,995,609
JBrowse link
G Cripto cripto, EGF-CFC family member decreases expression EXP Thalidomide results in decreased expression of CRIPTO mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 9:110,768,676...110,775,226
Ensembl chr 9:110,768,671...110,775,226
JBrowse link
G Crp C-reactive protein, pentraxin-related decreases expression ISO Thalidomide results in decreased expression of CRP protein CTD PMID:11339241 NCBI chr 1:172,525,623...172,527,533
Ensembl chr 1:172,525,622...172,660,598
JBrowse link
G Csf2 colony stimulating factor 2 (granulocyte-macrophage) decreases activity ISO Thalidomide results in decreased activity of CSF2 protein CTD PMID:17557286 NCBI chr11:54,138,096...54,140,725
Ensembl chr11:54,138,097...54,140,493
JBrowse link
G Csf3 colony stimulating factor 3 (granulocyte) decreases activity ISO Thalidomide results in decreased activity of CSF3 protein CTD PMID:17557286 NCBI chr11:98,591,287...98,594,457
Ensembl chr11:98,592,089...98,594,455
JBrowse link
G Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 decreases expression EXP Thalidomide results in decreased expression of CSGALNACT2 mRNA CTD PMID:26217789 NCBI chr 6:118,084,413...118,116,132
Ensembl chr 6:118,084,413...118,116,101
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression EXP Thalidomide results in increased expression of CXCL10 CTD PMID:17089043 NCBI chr 5:92,494,497...92,496,748
Ensembl chr 5:92,494,497...92,496,748
JBrowse link
G Cxcl15 C-X-C motif chemokine ligand 15 multiple interactions
decreases activity
ISO Thalidomide inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Thalidomide inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]
Thalidomide results in decreased activity of CXCL8 protein
CTD PMID:15687330 PMID:17557286 NCBI chr 5:90,942,393...90,950,926
Ensembl chr 5:90,942,393...90,950,926
JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 decreases expression ISO Thalidomide results in decreased expression of CXCR1 protein CTD PMID:16344495 NCBI chr 1:74,228,862...74,233,867
Ensembl chr 1:74,230,944...74,233,790
JBrowse link
G Cxcr2 C-X-C motif chemokine receptor 2 decreases expression ISO Thalidomide results in decreased expression of CXCR2 protein CTD PMID:16344495 NCBI chr 1:74,193,153...74,200,405
Ensembl chr 1:74,193,150...74,200,405
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO Thalidomide results in increased expression of CYCS protein CTD PMID:15982930 NCBI chr 6:50,539,543...50,543,549
Ensembl chr 6:50,539,543...50,543,518
JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases expression ISO Thalidomide results in increased expression of CYP2B6 mRNA CTD PMID:24460184 PMID:28496040 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049
JBrowse link
G Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 increases hydroxylation
multiple interactions
increases oxidation
ISO CYP2C19 protein results in increased hydroxylation of Thalidomide
[CYP2C19 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5'-hydroxythalidomide; [CYP2C19 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide; [CYP2C19 protein results in increased oxidation of Thalidomide] which results in increased abundance of 5'-hydroxythalidomide; [CYP2C19 protein results in increased oxidation of Thalidomide] which results in increased abundance of 5-hydroxythalidomide
CTD PMID:20443640 PMID:24350712 NCBI chr19:39,379,109...39,451,519
Ensembl chr19:39,378,000...39,451,519
JBrowse link
G Cyp3a13 cytochrome P450, family 3, subfamily a, polypeptide 13 multiple interactions
increases hydroxylation
increases expression
increases metabolic processing
ISO [CYP3A7 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide
Thalidomide results in increased expression of CYP3A5 mRNA
CYP3A5 protein results in increased metabolism of Thalidomide
[CYP3A5 protein results in increased hydroxylation of Thalidomide] which results in increased chemical synthesis of 5-hydroxythalidomide
CTD PMID:20443640 PMID:28496040 PMID:28745489 NCBI chr 5:137,891,195...137,923,872
Ensembl chr 5:137,891,194...137,919,881
JBrowse link
G Cyth3 cytohesin 3 decreases expression EXP Thalidomide results in decreased expression of CYTH3 mRNA CTD PMID:26217789 NCBI chr 5:143,608,202...143,696,005
Ensembl chr 5:143,608,202...143,696,005
JBrowse link
G Daam2 dishevelled associated activator of morphogenesis 2 decreases expression EXP Thalidomide results in decreased expression of DAAM2 mRNA CTD PMID:26217789 NCBI chr17:49,763,050...49,871,517
Ensembl chr17:49,763,050...49,871,371
JBrowse link
G Dbt dihydrolipoamide branched chain transacylase E2 decreases expression EXP Thalidomide results in decreased expression of DBT mRNA CTD PMID:26217789 NCBI chr 3:116,306,776...116,343,630
Ensembl chr 3:116,306,719...116,343,630
JBrowse link
G Ddb1 damage specific DNA binding protein 1 affects binding EXP Thalidomide binds to [CRBN protein binds to DDB1 protein] CTD PMID:25108355 NCBI chr19:10,582,961...10,607,186
Ensembl chr19:10,582,691...10,607,183
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Thalidomide analog results in increased expression of DDIT3 mRNA CTD PMID:20525221 NCBI chr10:127,126,662...127,132,160
Ensembl chr10:127,126,643...127,132,157
Ensembl chr10:127,126,643...127,132,157
JBrowse link
G Defa3 defensin, alpha, 3 increases expression EXP Thalidomide results in increased expression of DEFA3 mRNA CTD PMID:26217789 NCBI chr 8:21,777,425...21,778,393
Ensembl chr 8:21,777,425...21,778,393
JBrowse link
G Defb15 defensin beta 15 increases expression EXP Thalidomide results in increased expression of DEFB15 mRNA CTD PMID:26217789 NCBI chr 8:22,419,813...22,422,728
Ensembl chr 8:22,419,815...22,422,726
JBrowse link
G Des desmin multiple interactions ISO Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of DES protein] CTD PMID:17030452 NCBI chr 1:75,336,936...75,345,223
Ensembl chr 1:75,336,973...75,345,223
JBrowse link
G Dexi dexamethasone-induced transcript increases expression EXP Thalidomide results in increased expression of DEXI mRNA CTD PMID:26217789 NCBI chr16:10,348,071...10,360,918
Ensembl chr16:10,320,395...10,360,918
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression EXP Thalidomide results in decreased expression of DLGAP5 mRNA CTD PMID:26217789 NCBI chr14:47,625,238...47,655,657
Ensembl chr14:47,625,236...47,655,864
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 decreases expression EXP Thalidomide results in decreased expression of DLK1 mRNA CTD PMID:26217789 NCBI chr12:109,418,411...109,429,262
Ensembl chr12:109,418,749...109,429,262
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO Thalidomide analog results in increased expression of DNAJB1 mRNA CTD PMID:20525221 NCBI chr 8:84,334,804...84,339,282
Ensembl chr 8:84,334,822...84,339,282
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 increases expression ISO Thalidomide analog results in increased expression of DNAJB4 mRNA CTD PMID:20525221 NCBI chr 3:151,887,217...151,915,720
Ensembl chr 3:151,884,148...151,915,939
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO Thalidomide analog results in increased expression of DNAJB9 mRNA CTD PMID:20525221 NCBI chr12:44,252,680...44,256,851
Ensembl chr12:44,252,342...44,257,109
JBrowse link
G Dnajc19 DnaJ heat shock protein family (Hsp40) member C19 decreases expression EXP Thalidomide results in decreased expression of DNAJC19 mRNA CTD PMID:26217789 NCBI chr 3:34,111,429...34,135,503
Ensembl chr 3:34,110,169...34,135,470
JBrowse link
G Dus4l dihydrouridine synthase 4 like decreases expression EXP Thalidomide results in decreased expression of DUS4L mRNA CTD PMID:26217789 NCBI chr12:31,690,049...31,704,834
Ensembl chr12:31,690,049...31,704,825
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Thalidomide analog results in increased expression of DUSP1 mRNA CTD PMID:20525221 NCBI chr17:26,724,565...26,727,446
Ensembl chr17:26,724,564...26,781,102
JBrowse link
G Dusp10 dual specificity phosphatase 10 increases expression ISO Thalidomide analog results in increased expression of DUSP10 mRNA CTD PMID:20525221 NCBI chr 1:183,766,575...183,807,833
Ensembl chr 1:183,745,499...183,807,833
JBrowse link
G Dusp8 dual specificity phosphatase 8 increases expression ISO Thalidomide analog results in increased expression of DUSP8 mRNA CTD PMID:20525221 NCBI chr 7:141,633,224...141,649,799
Ensembl chr 7:141,633,227...141,649,580
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 decreases expression EXP Thalidomide results in decreased expression of EEF1E1 mRNA CTD PMID:26217789 NCBI chr13:38,829,667...38,843,004
Ensembl chr13:38,828,183...38,843,034
JBrowse link
G Efcab2 EF-hand calcium binding domain 2 decreases expression EXP Thalidomide results in decreased expression of EFCAB2 mRNA CTD PMID:26217789 NCBI chr 1:178,233,583...178,312,078
Ensembl chr 1:178,233,650...178,312,078
JBrowse link
G Eif1b eukaryotic translation initiation factor 1B decreases expression EXP Thalidomide results in decreased expression of EIF1B mRNA CTD PMID:26217789 NCBI chr 9:120,321,672...120,324,393
Ensembl chr 9:120,321,298...120,324,396
JBrowse link
G Eif4e eukaryotic translation initiation factor 4E decreases expression ISO Thalidomide results in decreased expression of EIF4E protein CTD PMID:18291259 NCBI chr 3:138,231,952...138,265,457
Ensembl chr 3:138,231,940...138,265,457
JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO Thalidomide inhibits the reaction [Lipopolysaccharides results in increased secretion of ELANE protein]; Thalidomide inhibits the reaction [lipoteichoic acid results in increased secretion of ELANE protein] CTD PMID:11302825 NCBI chr10:79,722,146...79,724,050
Ensembl chr10:79,722,081...79,724,049
JBrowse link
G Emc8 ER membrane protein complex subunit 8 decreases expression EXP Thalidomide results in decreased expression of EMC8 mRNA CTD PMID:26217789 NCBI chr 8:121,380,653...121,394,826
Ensembl chr 8:121,380,653...121,395,312
JBrowse link
G Epha10 Eph receptor A10 decreases expression ISO Thalidomide results in decreased expression of EPHA10 mRNA CTD PMID:32756504 NCBI chr 4:124,775,408...124,811,594
Ensembl chr 4:124,774,692...124,811,593
JBrowse link
G Ephb1 Eph receptor B1 decreases expression ISO Thalidomide results in decreased expression of EPHB1 mRNA CTD PMID:32756504 NCBI chr 9:101,799,327...102,231,892
Ensembl chr 9:101,799,327...102,231,892
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions ISO [ERBB2 protein co-treated with PIK3CA protein mutant form] results in increased susceptibility to Thalidomide metabolite CTD PMID:28745489 NCBI chr11:98,303,310...98,328,542
Ensembl chr11:98,303,296...98,328,542
JBrowse link
G Esd esterase D/formylglutathione hydrolase decreases expression EXP Thalidomide results in decreased expression of ESD mRNA CTD PMID:26217789 NCBI chr14:74,969,591...74,988,205
Ensembl chr14:74,969,737...74,988,205
JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 decreases expression ISO Thalidomide results in decreased expression of EYA1 mRNA CTD PMID:31711903 NCBI chr 1:14,239,177...14,381,259
Ensembl chr 1:14,239,178...14,380,459
JBrowse link
G F2r coagulation factor II thrombin receptor decreases expression ISO Thalidomide results in decreased expression of F2R mRNA; Thalidomide results in decreased expression of F2R protein CTD PMID:15618473 NCBI chr13:95,738,288...95,754,974
Ensembl chr13:95,738,311...95,754,995
JBrowse link
G Fabp5 fatty acid binding protein 5, epidermal decreases expression EXP Thalidomide results in decreased expression of FABP5 mRNA CTD PMID:26217789 NCBI chr 3:10,077,645...10,081,670
Ensembl chr 3:10,077,608...10,081,667
JBrowse link
G Fabp7 fatty acid binding protein 7, brain affects expression EXP Thalidomide affects the expression of FABP7 mRNA CTD PMID:26217789 NCBI chr10:57,661,019...57,664,546
Ensembl chr10:57,660,977...57,664,546
JBrowse link
G Fam174b family with sequence similarity 174, member B decreases expression EXP Thalidomide results in decreased expression of FAM174B mRNA CTD PMID:26217789 NCBI chr 7:73,390,055...73,426,667
Ensembl chr 7:73,390,050...73,426,667
JBrowse link
G Fas Fas cell surface death receptor decreases expression
increases expression
ISO Thalidomide results in decreased expression of FAS protein
Thalidomide results in increased expression of FAS mRNA
CTD PMID:16531263 PMID:18291259 NCBI chr19:34,267,926...34,305,175
Ensembl chr19:34,268,066...34,305,172
JBrowse link
G Fasl Fas ligand multiple interactions
decreases expression
EXP
ISO
Thalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of FASL mRNA]
Thalidomide results in decreased expression of FASLG protein
CTD PMID:16510725 PMID:16531263 NCBI chr 1:161,608,260...161,616,064
Ensembl chr 1:161,608,258...161,616,064
JBrowse link
G Fen1 flap structure specific endonuclease 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of FEN1 mRNA CTD PMID:18720364 NCBI chr19:10,176,496...10,181,757
Ensembl chr19:10,176,496...10,181,533
JBrowse link
G Fgd3 FYVE, RhoGEF and PH domain containing 3 increases expression EXP Thalidomide results in increased expression of FGD3 mRNA CTD PMID:26217789 NCBI chr13:49,415,030...49,473,783
Ensembl chr13:49,415,030...49,473,787
JBrowse link
G Fgf2 fibroblast growth factor 2 increases response to substance
affects expression
affects secretion
multiple interactions
decreases activity
decreases expression
ISO FGF2 protein results in increased susceptibility to Thalidomide
Thalidomide affects the expression of FGF2 mRNA; Thalidomide affects the expression of FGF2 protein
Thalidomide affects the secretion of FGF2 protein
Thalidomide promotes the reaction [FGF2 protein results in decreased expression of MMP2 protein]
Thalidomide results in decreased activity of FGF2 protein
[temozolomide co-treated with Thalidomide] results in decreased expression of FGF2 protein
Thalidomide results in decreased expression of FGF2 protein
CTD PMID:11555579 PMID:12644816 PMID:14558594 PMID:15863203 PMID:15939924 More... NCBI chr 3:37,402,616...37,464,255
Ensembl chr 3:37,402,495...37,464,257
JBrowse link
G Fgf8 fibroblast growth factor 8 increases expression ISO Thalidomide results in increased expression of FGF8 mRNA CTD PMID:31711903 NCBI chr19:45,724,930...45,731,380
Ensembl chr19:45,725,237...45,731,354
JBrowse link
G Fgfr1 fibroblast growth factor receptor 1 affects expression ISO Thalidomide affects the expression of FGFR1 mRNA CTD PMID:30834740 NCBI chr 8:26,008,808...26,067,819
Ensembl chr 8:26,003,670...26,065,734
JBrowse link
G Fgfr2 fibroblast growth factor receptor 2 decreases expression ISO Thalidomide results in decreased expression of FGFR2 mRNA; Thalidomide results in decreased expression of FGFR2 protein CTD PMID:30834740 NCBI chr 7:129,764,181...129,868,538
Ensembl chr 7:129,764,181...132,725,079
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 affects expression ISO Thalidomide affects the expression of FGFR3 mRNA CTD PMID:30834740 NCBI chr 5:33,879,068...33,894,412
Ensembl chr 5:33,879,018...33,894,412
JBrowse link
G Fos FBJ osteosarcoma oncogene increases expression ISO Thalidomide analog results in increased expression of FOS mRNA CTD PMID:20525221 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Fosb FBJ osteosarcoma oncogene B increases expression ISO Thalidomide analog results in increased expression of FOSB mRNA CTD PMID:20525221 NCBI chr 7:19,036,621...19,043,970
Ensembl chr 7:19,036,621...19,043,976
JBrowse link
G Foxc2 forkhead box C2 decreases expression ISO Thalidomide results in decreased expression of FOXC2 mRNA CTD PMID:31711903 NCBI chr 8:121,842,910...121,845,634
Ensembl chr 8:121,842,910...121,845,634
JBrowse link
G Foxred1 FAD-dependent oxidoreductase domain containing 1 decreases expression EXP Thalidomide results in decreased expression of FOXRED1 mRNA CTD PMID:26217789 NCBI chr 9:35,115,504...35,122,499
Ensembl chr 9:35,115,502...35,122,351
JBrowse link
G Fzd8 frizzled class receptor 8 decreases expression ISO Thalidomide results in decreased expression of FZD8 mRNA CTD PMID:24154490 NCBI chr18:9,212,856...9,216,201
Ensembl chr18:9,212,163...9,218,136
JBrowse link
G Gab3 growth factor receptor bound protein 2-associated protein 3 decreases expression EXP Thalidomide results in decreased expression of GAB3 mRNA CTD PMID:26217789 NCBI chr  X:74,032,151...74,128,511
Ensembl chr  X:74,010,449...74,129,064
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible 45 beta multiple interactions EXP Thalidomide inhibits the reaction [lipopolysaccharide A results in increased expression of GADD45B mRNA] CTD PMID:15797874 NCBI chr10:80,765,925...80,768,038
Ensembl chr10:80,765,907...80,768,038
JBrowse link
G Galm galactose mutarotase decreases expression EXP Thalidomide results in decreased expression of GALM mRNA CTD PMID:26217789 NCBI chr17:80,434,886...80,492,461
Ensembl chr17:80,434,900...80,492,530
JBrowse link
G Gata3 GATA binding protein 3 increases expression ISO Thalidomide results in increased expression of GATA3 protein CTD PMID:19428696 NCBI chr 2:9,861,889...9,894,845
Ensembl chr 2:9,861,889...9,894,845
JBrowse link
G Gcnt2 glucosaminyl (N-acetyl) transferase 2 (I blood group) decreases expression EXP Thalidomide results in decreased expression of GCNT2 mRNA CTD PMID:26217789 NCBI chr13:41,013,417...41,114,368
Ensembl chr13:41,013,230...41,114,368
JBrowse link
G Gemin2 gem nuclear organelle associated protein 2 decreases expression EXP Thalidomide results in decreased expression of GEMIN2 mRNA CTD PMID:26217789 NCBI chr12:59,060,177...59,075,256
Ensembl chr12:59,060,179...59,075,256
JBrowse link
G Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 decreases expression EXP Thalidomide results in decreased expression of GFRA2 mRNA CTD PMID:26217789 NCBI chr14:71,127,547...71,217,280
Ensembl chr14:71,127,560...71,217,278
JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble increases expression EXP Thalidomide results in increased expression of GOT1 mRNA CTD PMID:26217789 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044
JBrowse link
G Gp2 glycoprotein 2 zymogen granule membrane increases expression EXP Thalidomide results in increased expression of GP2 mRNA CTD PMID:26217789 NCBI chr 7:119,041,760...119,058,495
Ensembl chr 7:119,041,760...119,058,508
JBrowse link
G Gpatch4 G patch domain containing 4 decreases expression EXP Thalidomide results in decreased expression of GPATCH4 mRNA CTD PMID:26217789 NCBI chr 3:87,950,413...87,963,301
Ensembl chr 3:87,950,415...87,963,300
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions ISO Thalidomide inhibits the reaction [Carbon Tetrachloride results in decreased activity of GPX1 protein] CTD PMID:17030452 NCBI chr 9:108,216,279...108,217,541
Ensembl chr 9:108,216,102...108,217,542
JBrowse link
G Gpx8 glutathione peroxidase 8 (putative) decreases expression EXP Thalidomide results in decreased expression of GPX8 mRNA CTD PMID:26217789 NCBI chr13:113,179,287...113,182,944
Ensembl chr13:113,179,287...113,182,944
JBrowse link
G Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) decreases expression ISO Thalidomide results in decreased expression of GRIA3 mRNA CTD PMID:32756504 NCBI chr  X:40,489,351...40,767,478
Ensembl chr  X:40,489,731...40,767,478
JBrowse link
G Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) increases expression ISO Thalidomide results in increased expression of GRIA4 mRNA CTD PMID:32756504 NCBI chr 9:4,417,893...4,796,250
Ensembl chr 9:4,417,896...4,796,234
JBrowse link
G Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) decreases expression ISO Thalidomide results in decreased expression of GRIN2A mRNA CTD PMID:32756504 NCBI chr16:9,385,765...9,813,744
Ensembl chr16:9,385,762...9,813,424
JBrowse link
G Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3) decreases expression ISO Thalidomide results in decreased expression of GRIN2C mRNA CTD PMID:32756504 NCBI chr11:115,139,995...115,158,123
Ensembl chr11:115,139,995...115,158,069
JBrowse link
G Gtf2e1 general transcription factor II E, polypeptide 1 (alpha subunit) decreases expression EXP Thalidomide results in decreased expression of GTF2E1 mRNA CTD PMID:26217789 NCBI chr16:37,330,158...37,360,151
Ensembl chr16:37,330,152...37,360,151
JBrowse link
G Gulp1 GULP, engulfment adaptor PTB domain containing 1 decreases expression EXP Thalidomide results in decreased expression of GULP1 mRNA CTD PMID:26217789 NCBI chr 1:44,590,540...44,835,998
Ensembl chr 1:44,590,671...44,835,998
JBrowse link
G H2-Q1 histocompatibility 2, Q region locus 1 increases expression EXP Thalidomide results in increased expression of H2-Q1 mRNA CTD PMID:26217789 NCBI chr17:35,539,503...35,547,118
Ensembl chr17:35,539,381...35,544,075
JBrowse link
G H2-T23 histocompatibility 2, T region locus 23 affects expression ISO Thalidomide affects the expression of HLA-E mRNA CTD PMID:25811541 NCBI chr17:36,340,869...36,343,593
Ensembl chr17:36,340,665...36,343,747
JBrowse link
G H2ac6 H2A clustered histone 6 decreases expression EXP Thalidomide results in decreased expression of H2AC15 mRNA CTD PMID:26217789 NCBI chr13:23,867,456...23,867,942
Ensembl chr13:23,865,450...23,867,931
JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression EXP Thalidomide results in decreased expression of H2BC12 mRNA CTD PMID:26217789 NCBI chr13:22,219,991...22,220,490
Ensembl chr13:22,220,040...22,220,515
JBrowse link
G H2bc27 H2B clustered histone 27 decreases expression EXP Thalidomide results in decreased expression of H2BC27 mRNA CTD PMID:26217789 NCBI chr11:58,839,737...58,840,198
Ensembl chr11:58,839,746...58,840,359
JBrowse link
G H2bc4 H2B clustered histone 4 decreases expression EXP Thalidomide results in decreased expression of H2BC4 mRNA CTD PMID:26217789 NCBI chr13:23,868,182...23,876,805
Ensembl chr13:23,868,182...23,876,891
JBrowse link
G H3c1 H3 clustered histone 1 decreases expression EXP Thalidomide results in decreased expression of H3C1 mRNA CTD PMID:26217789 NCBI chr13:23,945,868...23,946,369
Ensembl chr13:23,945,836...23,946,369
JBrowse link
G H3c7 H3 clustered histone 7 decreases expression EXP Thalidomide results in decreased expression of H3C15 mRNA CTD PMID:26217789 NCBI chr13:23,728,222...23,729,124
Ensembl chr13:23,728,222...23,729,482
JBrowse link
G H4c11 H4 clustered histone 11 decreases expression EXP Thalidomide results in decreased expression of H4C11 mRNA CTD PMID:26217789 NCBI chr13:21,919,204...21,919,626
Ensembl chr13:21,919,234...21,920,007
JBrowse link
G H4c14 H4 clustered histone 14 decreases expression EXP Thalidomide results in decreased expression of H4C3 mRNA CTD PMID:26217789 NCBI chr 3:96,170,250...96,170,633
Ensembl chr 3:96,168,998...96,170,627
JBrowse link
G H4c2 H4 clustered histone 2 decreases expression EXP Thalidomide results in decreased expression of H4C14 mRNA CTD PMID:26217789 NCBI chr13:23,940,920...23,941,369
Ensembl chr13:23,940,996...23,941,392
JBrowse link
G H4c4 H4 clustered histone 4 decreases expression EXP Thalidomide results in decreased expression of H4C4 mRNA CTD PMID:26217789 NCBI chr13:23,765,551...23,765,952
Ensembl chr13:23,765,581...23,766,718
JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 decreases expression EXP Thalidomide results in decreased expression of HCN1 mRNA CTD PMID:26217789 NCBI chr13:117,738,856...118,117,564
Ensembl chr13:117,738,856...118,123,954
JBrowse link
G Herpud1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 increases expression ISO Thalidomide analog results in increased expression of HERPUD1 mRNA CTD PMID:20525221 NCBI chr 8:95,113,057...95,121,999
Ensembl chr 8:95,113,066...95,122,005
JBrowse link
G Hgf hepatocyte growth factor affects expression
decreases activity
affects secretion
ISO Thalidomide affects the expression of HGF mRNA; Thalidomide affects the expression of HGF protein
Thalidomide results in decreased activity of HGF protein
Thalidomide affects the secretion of HGF protein
CTD PMID:15939924 PMID:17557286 NCBI chr 5:16,758,493...16,827,448
Ensembl chr 5:16,758,493...16,825,150
JBrowse link
G Hirip3 HIRA interacting protein 3 decreases expression EXP Thalidomide results in decreased expression of HIRIP3 mRNA CTD PMID:26217789 NCBI chr 7:126,461,155...126,464,549
Ensembl chr 7:126,461,144...126,464,549
JBrowse link
G Hmgn5 high-mobility group nucleosome binding domain 5 decreases expression EXP Thalidomide results in decreased expression of HMGN5 mRNA CTD PMID:26217789 NCBI chr  X:108,048,143...108,056,986
Ensembl chr  X:108,048,140...108,057,010
JBrowse link
G Hoxb7 homeobox B7 increases expression ISO Thalidomide results in increased expression of HOXB7 mRNA CTD PMID:31711903 NCBI chr11:96,176,431...96,180,989
Ensembl chr11:96,177,449...96,180,988
JBrowse link
G Hoxb9 homeobox B9 increases expression ISO Thalidomide results in increased expression of HOXB9 mRNA CTD PMID:31711903 NCBI chr11:96,162,156...96,167,421
Ensembl chr11:96,162,283...96,167,421
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases expression EXP Thalidomide results in decreased expression of HSD11B2 mRNA CTD PMID:26217789 NCBI chr 8:106,245,378...106,250,620
Ensembl chr 8:106,245,387...106,250,620
JBrowse link
G Hsf1 heat shock factor 1 decreases expression EXP Thalidomide results in decreased expression of HSF1 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr15:76,361,562...76,385,355
Ensembl chr15:76,361,622...76,386,113
JBrowse link
G Hspb1 heat shock protein 1 decreases expression EXP Thalidomide results in decreased expression of HSPB1 mRNA CTD PMID:26217789 NCBI chr 5:135,916,773...135,918,417
Ensembl chr 5:135,916,773...135,918,417
JBrowse link
G Hsph1 heat shock 105kDa/110kDa protein 1 increases expression ISO Thalidomide analog results in increased expression of HSPH1 mRNA CTD PMID:20525221 NCBI chr 5:149,540,308...149,562,594
Ensembl chr 5:149,537,752...149,559,841
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases response to substance
decreases expression
ISO ICAM1 gene SNP results in increased susceptibility to Thalidomide
Thalidomide results in decreased expression of ICAM1 mRNA; Thalidomide results in decreased expression of ICAM1 protein
CTD PMID:17174718 PMID:21245421 NCBI chr 9:20,927,236...20,940,110
Ensembl chr 9:20,927,281...20,940,113
JBrowse link
G Idnk idnK gluconokinase homolog (E. coli) decreases expression EXP Thalidomide results in decreased expression of IDNK mRNA CTD PMID:26217789 NCBI chr13:58,305,076...58,315,358
Ensembl chr13:58,305,463...58,312,507
JBrowse link
G Ifng interferon gamma multiple interactions
affects expression
increases expression
decreases expression
EXP
ISO
[Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG protein
Thalidomide affects the expression of IFNG mRNA
Thalidomide results in increased expression of IFNG; Thalidomide results in increased expression of IFNG protein
Thalidomide inhibits the reaction [irinotecan results in increased expression of IFNG protein]; Thalidomide promotes the reaction [irinotecan results in increased expression of IFNG protein]
Thalidomide results in decreased expression of IFNG protein
CTD PMID:15588918 PMID:16078585 PMID:16454849 PMID:16514283 PMID:16815871 More... NCBI chr10:118,276,951...118,281,799
Ensembl chr10:118,276,951...118,281,797
JBrowse link
G Ift27 intraflagellar transport 27 decreases expression EXP Thalidomide results in decreased expression of IFT27 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr15:78,043,660...78,058,281
Ensembl chr15:78,043,663...78,058,307
JBrowse link
G Ift70a1 intraflagellar transport 70A1 decreases expression EXP Thalidomide results in decreased expression of IFT70A1 mRNA CTD PMID:26217789 NCBI chr 2:75,809,450...75,812,311
Ensembl chr 2:75,808,591...75,812,311
JBrowse link
G Ift74 intraflagellar transport 74 decreases expression EXP Thalidomide results in decreased expression of IFT74 mRNA CTD PMID:26217789 NCBI chr 4:94,491,503...94,581,470
Ensembl chr 4:94,502,728...94,581,466
JBrowse link
G Igf1 insulin-like growth factor 1 affects expression ISO Thalidomide affects the expression of IGF1 mRNA CTD PMID:15939924 NCBI chr10:87,694,127...87,772,909
Ensembl chr10:87,694,127...87,772,904
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 affects expression
decreases expression
ISO
EXP
Thalidomide affects the expression of IGFBP3 mRNA
Thalidomide results in decreased expression of IGFBP3 mRNA
CTD PMID:15939924 PMID:26217789 NCBI chr11:7,156,086...7,165,498
Ensembl chr11:7,156,086...7,163,923
JBrowse link
G Ighv9-2 immunoglobulin heavy variable V9-2 increases expression EXP Thalidomide results in increased expression of IGHV9-2 mRNA CTD PMID:26217789 NCBI chr12:114,072,621...114,073,050
Ensembl chr12:114,072,621...114,073,050
JBrowse link
G Igkv8-30 immunoglobulin kappa chain variable 8-30 decreases expression EXP Thalidomide results in decreased expression of IGKV8-30 mRNA CTD PMID:26217789 NCBI chr 6:70,094,045...70,094,601
Ensembl chr 6:70,094,045...70,094,604
JBrowse link
G Il10 interleukin 10 affects expression
decreases expression
ISO
EXP
Thalidomide affects the expression of IL10 mRNA
Thalidomide results in decreased expression of IL10 protein
CTD PMID:16454849 PMID:16514283 NCBI chr 1:130,947,459...130,952,707
Ensembl chr 1:130,947,582...130,952,711
JBrowse link
G Il12a interleukin 12a multiple interactions ISO Thalidomide results in decreased expression of [IL12A protein binds to IL12B protein] CTD PMID:11788559 NCBI chr 3:68,597,977...68,605,881
Ensembl chr 3:68,597,977...68,605,880
JBrowse link
G Il12b interleukin 12b multiple interactions ISO
EXP
Thalidomide results in decreased expression of [IL12A protein binds to IL12B protein]
Thalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of IL12B mRNA]
CTD PMID:11788559 PMID:16510725 NCBI chr11:44,290,890...44,305,504
Ensembl chr11:44,290,890...44,304,860
JBrowse link
G Il18 interleukin 18 increases expression EXP Thalidomide results in increased expression of IL18 CTD PMID:17089043 NCBI chr 9:50,466,000...50,493,141
Ensembl chr 9:50,466,127...50,493,140
JBrowse link
G Il1b interleukin 1 beta decreases expression
multiple interactions
ISO
EXP
Thalidomide results in decreased expression of IL1B protein
Thalidomide inhibits the reaction [irinotecan results in increased expression of IL1B protein]; Thalidomide promotes the reaction [irinotecan results in increased expression of IL1B protein]
Thalidomide inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of IL1B protein]; Thalidomide inhibits the reaction [Paraquat results in increased expression of IL1B mRNA]
CTD PMID:15863203 PMID:16815871 PMID:23510834 PMID:25478868 NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059
JBrowse link
G Il1r1 interleukin 1 receptor, type I decreases expression ISO Thalidomide results in decreased expression of IL1R1 mRNA CTD PMID:15618473 NCBI chr 1:40,261,651...40,355,361
Ensembl chr 1:40,264,240...40,356,417
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions EXP Thalidomide promotes the reaction [SOD1 gene mutant form results in increased expression of IL1RN mRNA] CTD PMID:16510725 NCBI chr 2:24,226,872...24,241,503
Ensembl chr 2:24,226,865...24,241,506
JBrowse link
G Il2 interleukin 2 multiple interactions
decreases expression
EXP
ISO
[Thalidomide co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 protein
Thalidomide results in decreased expression of IL2 protein
Thalidomide inhibits the reaction [irinotecan results in decreased expression of IL2 protein]; Thalidomide promotes the reaction [irinotecan results in decreased expression of IL2 protein]
CTD PMID:15588918 PMID:16815871 NCBI chr 3:37,174,862...37,180,103
Ensembl chr 3:37,174,672...37,180,108
JBrowse link
G Il4 interleukin 4 increases expression ISO Thalidomide results in increased expression of IL4 protein CTD PMID:16078585 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496
JBrowse link
G Il6 interleukin 6 decreases secretion
decreases activity
multiple interactions
ISO
EXP
Thalidomide analog results in decreased secretion of IL6 protein
Thalidomide results in decreased activity of IL6 protein
Thalidomide inhibits the reaction [irinotecan results in increased expression of IL6 protein]; Thalidomide inhibits the reaction [Paraquat results in increased expression of IL6 mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of IL6 protein]
Thalidomide inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of IL6 protein]; Thalidomide inhibits the reaction [Paraquat results in increased expression of IL6 mRNA]
CTD PMID:15858615 PMID:16815871 PMID:17557286 PMID:23510834 PMID:25478868 More... NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979
JBrowse link
G Il6st interleukin 6 signal transducer decreases expression ISO Thalidomide results in decreased expression of IL6ST mRNA CTD PMID:15618473 NCBI chr13:112,600,604...112,643,394
Ensembl chr13:112,600,604...112,646,620
JBrowse link
G Ing3 inhibitor of growth family, member 3 increases expression ISO Thalidomide analog results in increased expression of ING3 mRNA CTD PMID:20525221 NCBI chr 6:21,948,002...21,976,037
Ensembl chr 6:21,949,570...21,976,037
JBrowse link
G Ipp IAP promoted placental gene decreases expression EXP Thalidomide results in decreased expression of IPP mRNA CTD PMID:26217789 NCBI chr 4:116,364,710...116,400,607
Ensembl chr 4:116,364,746...116,395,440
JBrowse link
G Jun jun proto-oncogene increases expression ISO Thalidomide analog results in increased expression of JUN mRNA CTD PMID:20525221 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459
JBrowse link
G Kalrn kalirin, RhoGEF kinase decreases expression ISO Thalidomide results in decreased expression of KALRN mRNA CTD PMID:32756504 NCBI chr16:33,789,443...34,393,647
Ensembl chr16:33,789,443...34,393,902
JBrowse link
G Kdr kinase insert domain protein receptor multiple interactions ISO sphingosine 1-phosphate inhibits the reaction [Thalidomide results in decreased expression of KDR mRNA] CTD PMID:15741222 NCBI chr 5:76,093,487...76,139,880
Ensembl chr 5:76,093,487...76,139,118
JBrowse link
G Kif2c kinesin family member 2C multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of KIF2C mRNA CTD PMID:18720364 NCBI chr 4:117,016,830...117,039,821
Ensembl chr 4:117,016,836...117,039,836
JBrowse link
G Klhl4 kelch-like 4 decreases expression EXP Thalidomide results in decreased expression of KLHL4 mRNA CTD PMID:26217789 NCBI chr  X:113,384,030...113,470,826
Ensembl chr  X:113,384,030...113,470,526
JBrowse link
G Klk1 kallikrein 1 decreases expression EXP Thalidomide results in decreased expression of KLK1 mRNA CTD PMID:26217789 NCBI chr 7:43,874,784...43,879,046
Ensembl chr 7:43,874,784...43,879,042
JBrowse link
G Klra14-ps killer cell lectin-like receptor subfamily A, member 14, pseudogene increases expression EXP Thalidomide results in increased expression of KLRA14-PS mRNA CTD PMID:26217789 NCBI chr 6:130,126,069...130,137,711
Ensembl chr 6:130,126,069...130,137,711
JBrowse link
G Krtap1-4 keratin associated protein 1-4 increases expression EXP Thalidomide results in increased expression of KRTAP1-4 mRNA CTD PMID:26217789 NCBI chr11:99,473,375...99,474,503
Ensembl chr11:99,473,888...99,474,480
JBrowse link
G Lats2 large tumor suppressor 2 increases expression ISO Thalidomide analog results in increased expression of LATS2 mRNA CTD PMID:20525221 NCBI chr14:57,927,119...57,983,669
Ensembl chr14:57,927,119...57,995,845
Ensembl chr14:57,927,119...57,995,845
JBrowse link
G Lefty2 left-right determination factor 2 decreases expression EXP Thalidomide results in decreased expression of LEFTY2 mRNA CTD PMID:26217789 NCBI chr 1:180,720,673...180,726,672
Ensembl chr 1:180,720,673...180,726,668
JBrowse link
G Lrr1 leucine rich repeat protein 1 decreases expression EXP Thalidomide results in decreased expression of LRR1 mRNA CTD PMID:26217789 NCBI chr12:69,215,588...69,225,786
Ensembl chr12:69,215,588...69,225,783
JBrowse link
G Ltf lactotransferrin multiple interactions ISO Thalidomide inhibits the reaction [Lipopolysaccharides results in increased secretion of LTF protein]; Thalidomide inhibits the reaction [lipoteichoic acid results in increased secretion of LTF protein] CTD PMID:11302825 NCBI chr 9:110,848,360...110,871,834
Ensembl chr 9:110,848,339...110,871,835
JBrowse link
G Ly6g lymphocyte antigen 6 family member G increases expression EXP Thalidomide results in increased expression of LY6G mRNA CTD PMID:26217789 NCBI chr15:75,027,110...75,030,977
Ensembl chr15:75,027,089...75,030,975
JBrowse link
G Ly96 lymphocyte antigen 96 decreases expression EXP Thalidomide results in decreased expression of LY96 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 1:16,758,680...16,779,829
Ensembl chr 1:16,758,275...16,779,835
JBrowse link
G Lyrm2 LYR motif containing 2 decreases expression EXP Thalidomide results in decreased expression of LYRM2 mRNA CTD PMID:26217789 NCBI chr 4:32,800,259...32,802,268
Ensembl chr 4:32,800,253...32,801,559
JBrowse link
G Lyrm4 LYR motif containing 4 decreases expression EXP Thalidomide results in decreased expression of LYRM4 mRNA CTD PMID:26217789 NCBI chr13:36,162,778...36,301,543
Ensembl chr13:36,162,378...36,301,509
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO Thalidomide promotes the reaction [temozolomide results in increased expression of MAP1LC3B protein] CTD PMID:19567134 NCBI chr 8:122,317,177...122,325,499
Ensembl chr 8:122,317,100...122,325,499
JBrowse link
G Mapk1 mitogen-activated protein kinase 1 increases phosphorylation ISO Thalidomide analog results in increased phosphorylation of MAPK1 protein CTD PMID:15858615 NCBI chr16:16,801,246...16,865,317
Ensembl chr16:16,801,246...16,865,317
JBrowse link
G Mapk14 mitogen-activated protein kinase 14 increases phosphorylation ISO Thalidomide analog results in increased phosphorylation of MAPK14 protein CTD PMID:15858615 NCBI chr17:28,910,316...28,967,379
Ensembl chr17:28,910,303...28,967,380
JBrowse link
G Mapk3 mitogen-activated protein kinase 3 increases phosphorylation ISO Thalidomide analog results in increased phosphorylation of MAPK3 protein CTD PMID:15858615 NCBI chr 7:126,358,798...126,364,988
Ensembl chr 7:126,358,773...126,364,991
JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 decreases expression ISO Thalidomide analog results in decreased expression of MCL1 protein CTD PMID:15858615 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of MCM5 mRNA CTD PMID:18720364 NCBI chr 8:75,836,096...75,855,067
Ensembl chr 8:75,836,197...75,855,067
JBrowse link
G Mcpt8 mast cell protease 8 increases expression EXP Thalidomide results in increased expression of MCPT8 mRNA CTD PMID:26217789 NCBI chr14:56,319,620...56,322,951
Ensembl chr14:56,319,623...56,322,730
JBrowse link
G Meis2 Meis homeobox 2 multiple interactions ISO Thalidomide inhibits the reaction [CRBN protein binds to and results in increased ubiquitination of and results in increased degradation of MEIS2 protein] CTD PMID:25043012 NCBI chr 2:115,691,745...115,897,925
Ensembl chr 2:115,693,545...115,896,320
JBrowse link
G Meox1 mesenchyme homeobox 1 decreases expression ISO Thalidomide results in decreased expression of MEOX1 mRNA CTD PMID:31711903 NCBI chr11:101,768,336...101,785,309
Ensembl chr11:101,768,336...101,785,200
JBrowse link
G Mesp2 mesoderm posterior 2 decreases expression ISO Thalidomide results in decreased expression of MESP2 mRNA CTD PMID:31711903 NCBI chr 7:79,460,475...79,463,179
Ensembl chr 7:79,460,475...79,463,187
JBrowse link
G Mettl5 methyltransferase 5, N6-adenosine decreases expression EXP Thalidomide results in decreased expression of METTL5 mRNA CTD PMID:26217789 NCBI chr 2:69,701,539...69,717,961
Ensembl chr 2:69,701,542...69,715,959
JBrowse link
G Mir101c microRNA 101c increases expression EXP Thalidomide results in increased expression of MIR101C mRNA CTD PMID:26217789 NCBI chr 9:3,038,669...3,038,743
Ensembl chr 9:3,038,669...3,038,743
JBrowse link
G Mir301b microRNA 301b increases expression EXP Thalidomide results in increased expression of MIR301B mRNA CTD PMID:26217789 NCBI chr16:16,942,264...16,942,360
Ensembl chr16:16,942,264...16,942,360
JBrowse link
G Mir3081 microRNA 3081 increases expression EXP Thalidomide results in increased expression of MIR3081 mRNA CTD PMID:26217789 NCBI chr16:44,378,409...44,378,492
Ensembl chr16:44,378,409...44,378,492
JBrowse link
G Mir3095 microRNA 3095 decreases expression EXP Thalidomide results in decreased expression of MIR3095 mRNA CTD PMID:26217789 NCBI chr 4:58,441,012...58,441,098
Ensembl chr 4:58,441,012...58,441,098
JBrowse link
G Mir30e microRNA 30e decreases expression EXP Thalidomide results in decreased expression of MIR30E mRNA CTD PMID:26217789 NCBI chr 4:120,629,803...120,629,894
Ensembl chr 4:120,629,803...120,629,894
JBrowse link
G Mir3102 microRNA 3102 increases expression EXP Thalidomide results in increased expression of MIR3102 mRNA CTD PMID:26217789 NCBI chr 7:100,531,513...100,531,616
Ensembl chr 7:100,531,513...100,531,616
JBrowse link
G Mir3473b microRNA 3473b increases expression EXP Thalidomide results in increased expression of MIR3473B mRNA CTD PMID:26217789 NCBI chr10:41,546,735...41,546,789
Ensembl chr10:41,546,735...41,546,789
JBrowse link
G Mir3965 microRNA 3965 decreases expression EXP Thalidomide results in decreased expression of MIR3965 mRNA CTD PMID:26217789 NCBI chr 5:134,355,308...134,355,376
Ensembl chr 5:134,355,308...134,355,376
JBrowse link
G Mir449c microRNA 449c increases expression EXP Thalidomide results in increased expression of MIR449C mRNA CTD PMID:26217789 NCBI chr13:113,172,517...113,172,625
Ensembl chr13:113,172,517...113,172,625
JBrowse link
G Mir5103 microRNA 5103 increases expression EXP Thalidomide results in increased expression of MIR5103 mRNA CTD PMID:26217789 NCBI chr 1:34,472,202...34,472,280
Ensembl chr 1:34,472,202...34,472,280
JBrowse link
G Mixl1 Mix paired-like homeobox decreases expression EXP Thalidomide results in decreased expression of MIXL1 mRNA CTD PMID:26217789 NCBI chr 1:180,520,608...180,524,599
Ensembl chr 1:180,520,608...180,524,599
JBrowse link
G Mki67 antigen identified by monoclonal antibody Ki 67 multiple interactions
decreases expression
ISO [Azacitidine co-treated with Thalidomide] affects the expression of MKI67 mRNA
Thalidomide results in decreased expression of MKI67 protein
CTD PMID:18720364 PMID:34520751 NCBI chr 7:135,291,513...135,318,286
Ensembl chr 7:135,291,513...135,318,090
JBrowse link
G Mlf2 myeloid leukemia factor 2 decreases expression EXP Thalidomide results in decreased expression of MLF2 mRNA CTD PMID:26217789 NCBI chr 6:124,908,351...124,913,112
Ensembl chr 6:124,908,349...124,914,201
JBrowse link
G Mme membrane metallo endopeptidase decreases expression EXP Thalidomide results in decreased expression of MME mRNA CTD PMID:26217789 NCBI chr 3:63,202,632...63,291,134
Ensembl chr 3:63,148,958...63,293,451
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO Thalidomide promotes the reaction [FGF2 protein results in decreased expression of MMP2 protein]
Thalidomide results in decreased expression of MMP2 protein
CTD PMID:14558594 PMID:15863203 NCBI chr 8:93,553,920...93,580,049
Ensembl chr 8:93,553,919...93,580,048
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Thalidomide results in decreased expression of MMP9 protein CTD PMID:15863203 NCBI chr 2:164,782,246...164,797,770
Ensembl chr 2:164,782,700...164,797,770
JBrowse link
G Moxd1 monooxygenase, DBH-like 1 decreases expression EXP Thalidomide results in decreased expression of MOXD1 mRNA CTD PMID:26217789 NCBI chr10:24,099,415...24,178,681
Ensembl chr10:24,099,415...24,178,688
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Thalidomide inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased activity of MPO protein]; Thalidomide inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:15138204 PMID:25478868 NCBI chr11:87,684,610...87,695,238
Ensembl chr11:87,684,407...87,695,239
JBrowse link
G Mpp1 membrane protein, palmitoylated decreases expression EXP Thalidomide results in decreased expression of MPP1 mRNA CTD PMID:26217789 NCBI chr  X:74,153,339...74,174,622
Ensembl chr  X:74,153,339...74,174,622
JBrowse link
G Mrpl32 mitochondrial ribosomal protein L32 decreases expression EXP Thalidomide results in decreased expression of MRPL32 mRNA CTD PMID:26217789 NCBI chr13:14,784,886...14,787,622
Ensembl chr13:14,782,769...14,787,750
JBrowse link
G Mrpl34 mitochondrial ribosomal protein L34 decreases expression EXP Thalidomide results in decreased expression of MRPL34 mRNA CTD PMID:26217789 NCBI chr 8:71,917,570...71,918,397
Ensembl chr 8:71,917,603...71,918,391
JBrowse link
G Mrpl47 mitochondrial ribosomal protein L47 decreases expression EXP Thalidomide results in decreased expression of MRPL47 mRNA CTD PMID:26217789 NCBI chr 3:32,781,646...32,790,904
Ensembl chr 3:32,779,546...32,791,754
JBrowse link
G Mrpl52 mitochondrial ribosomal protein L52 decreases expression EXP Thalidomide results in decreased expression of MRPL52 mRNA CTD PMID:26217789 NCBI chr14:54,664,366...54,667,207
Ensembl chr14:54,664,366...54,667,213
JBrowse link
G Mrps21 mitochondrial ribosomal protein S21 decreases expression EXP Thalidomide results in decreased expression of MRPS21 mRNA CTD PMID:26217789 NCBI chr 3:95,769,946...95,778,826
Ensembl chr 3:95,769,946...95,778,831
JBrowse link
G Mtfr2 mitochondrial fission regulator 2 decreases expression EXP Thalidomide results in decreased expression of MTFR2 mRNA CTD PMID:26217789 NCBI chr10:20,223,491...20,237,415
Ensembl chr10:20,223,516...20,237,050
JBrowse link
G Mup6 major urinary protein 6 decreases expression EXP Thalidomide results in decreased expression of MUP6 mRNA CTD PMID:26217789 NCBI chr 4:60,003,481...60,007,274
Ensembl chr 4:59,964,294...60,007,274
JBrowse link
G Myb myeloblastosis oncogene multiple interactions
decreases activity
decreases phosphorylation
ISO CAT protein inhibits the reaction [Thalidomide results in decreased activity of MYB protein]
Thalidomide results in decreased phosphorylation of MYB protein
CTD PMID:16616857 NCBI chr10:21,000,829...21,036,883
Ensembl chr10:21,000,834...21,036,883
JBrowse link
G Mybpc3 myosin binding protein C, cardiac decreases expression EXP Thalidomide results in decreased expression of MYBPC3 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 2:90,948,459...90,966,862
Ensembl chr 2:90,948,489...90,966,861
JBrowse link
G Myd88 myeloid differentiation primary response gene 88 decreases expression EXP Thalidomide results in decreased expression of MYD88 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 9:119,165,000...119,169,084
Ensembl chr 9:119,165,000...119,170,477
JBrowse link
G Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha affects expression EXP Thalidomide affects the expression of MYH6 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr14:55,179,378...55,205,553
Ensembl chr14:55,179,378...55,204,384
JBrowse link
G Myl3 myosin, light polypeptide 3 affects expression
decreases expression
EXP Thalidomide affects the expression of MYL3 mRNA
Thalidomide results in decreased expression of MYL3 mRNA
CTD PMID:26006729 PMID:26217789 NCBI chr 9:110,592,746...110,598,870
Ensembl chr 9:110,570,929...110,598,866
JBrowse link
G Myl7 myosin, light polypeptide 7, regulatory decreases expression EXP Thalidomide results in decreased expression of MYL7 mRNA CTD PMID:26217789 NCBI chr11:5,846,637...5,848,782
Ensembl chr11:5,846,637...5,848,782
JBrowse link
G Mylk myosin, light polypeptide kinase increases expression EXP Thalidomide results in increased expression of MYLK mRNA CTD PMID:26217789 NCBI chr16:34,565,569...34,822,806
Ensembl chr16:34,565,580...34,822,790
JBrowse link
G Myom1 myomesin 1 decreases expression EXP Thalidomide results in decreased expression of MYOM1 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr17:71,326,455...71,433,851
Ensembl chr17:71,309,628...71,433,851
JBrowse link
G Naa20 N(alpha)-acetyltransferase 20, NatB catalytic subunit decreases expression EXP Thalidomide results in decreased expression of NAA20 mRNA CTD PMID:26217789 NCBI chr 2:145,743,454...145,758,345
Ensembl chr 2:145,744,019...145,758,345
JBrowse link
G Nanog Nanog homeobox decreases expression EXP Thalidomide results in decreased expression of NANOG mRNA CTD PMID:26217789 NCBI chr 6:122,684,448...122,691,592
Ensembl chr 6:122,684,448...122,691,592
JBrowse link
G Naxe NAD(P)HX epimerase decreases expression EXP Thalidomide results in decreased expression of NAXE mRNA CTD PMID:26217789 NCBI chr 3:87,963,827...87,965,851
Ensembl chr 3:87,963,827...87,965,802
JBrowse link
G Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 decreases expression EXP Thalidomide results in decreased expression of NDUFB8 mRNA CTD PMID:26217789 NCBI chr19:44,537,010...44,543,881
Ensembl chr19:44,537,011...44,543,879
JBrowse link
G Nebl nebulette decreases expression EXP Thalidomide results in decreased expression of NEBL mRNA CTD PMID:26217789 NCBI chr 2:17,347,484...17,740,634
Ensembl chr 2:17,348,720...17,736,275
JBrowse link
G Neurod4 neurogenic differentiation 4 increases expression EXP Thalidomide results in increased expression of NEUROD4 mRNA CTD PMID:26217789 NCBI chr10:130,104,021...130,116,123
Ensembl chr10:130,104,021...130,116,109
JBrowse link
G Neurog2 neurogenin 2 increases expression ISO Thalidomide results in increased expression of NEUROG2 mRNA CTD PMID:31711903 NCBI chr 3:127,426,382...127,429,285
Ensembl chr 3:127,426,784...127,429,280
JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 multiple interactions EXP Thalidomide promotes the reaction [Paraquat results in increased expression of NFE2L2 mRNA]; Thalidomide promotes the reaction [Paraquat results in increased expression of NFE2L2 protein] CTD PMID:25579023 NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985
JBrowse link
G Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 multiple interactions
decreases expression
ISO [resveratrol co-treated with Thalidomide] results in decreased activity of [RELA protein binds to NFKB1 protein]
Thalidomide results in decreased expression of NFKB1 protein
CTD PMID:16333628 PMID:17164350 NCBI chr 3:135,290,416...135,397,422
Ensembl chr 3:135,290,416...135,397,308
JBrowse link
G Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha multiple interactions
increases expression
ISO Thalidomide inhibits the reaction [TGFB1 protein results in increased degradation of NFKBIA protein]; Thalidomide inhibits the reaction [TGFB1 protein results in increased phosphorylation of NFKBIA protein]; Thalidomide inhibits the reaction [TGFB1 protein results in increased transport of NFKBIA protein]; Thalidomide inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]
Thalidomide inhibits the reaction [Carbon Tetrachloride results in decreased expression of NFKBIA protein]; Thalidomide inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]
Thalidomide results in increased expression of NFKBIA protein
CTD PMID:15687330 PMID:16288038 PMID:16604421 PMID:16943688 PMID:17174718 NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432
JBrowse link
G Nhlh1 nescient helix loop helix 1 increases expression EXP Thalidomide results in increased expression of NHLH1 mRNA CTD PMID:26217789 NCBI chr 1:171,879,859...171,885,163
Ensembl chr 1:171,879,859...171,885,140
JBrowse link
G Nms neuromedin S increases expression EXP Thalidomide results in increased expression of NMS mRNA CTD PMID:26217789 NCBI chr 1:38,978,230...38,989,357
Ensembl chr 1:38,978,230...38,989,357
JBrowse link
G Nos2 nitric oxide synthase 2, inducible multiple interactions ISO Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of NOS2 mRNA] CTD PMID:16604421 NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080
JBrowse link
G Nppb natriuretic peptide type B multiple interactions ISO [Thalidomide co-treated with Dexamethasone] results in increased expression of NPPB protein CTD PMID:18414984 NCBI chr 4:148,070,264...148,071,662
Ensembl chr 4:148,070,245...148,071,662
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide quinone reductase 2 decreases expression EXP Thalidomide results in decreased expression of NQO2 mRNA CTD PMID:26217789 NCBI chr13:34,148,642...34,172,448
Ensembl chr13:34,148,670...34,172,426
JBrowse link
G Nr1h5 nuclear receptor subfamily 1, group H, member 5 decreases expression EXP Thalidomide results in decreased expression of NR1H5 mRNA CTD PMID:26217789 NCBI chr 3:102,846,974...102,871,607
Ensembl chr 3:102,846,974...102,871,449
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression ISO Thalidomide results in increased expression of NR1I2 mRNA CTD PMID:28496040 NCBI chr16:38,068,711...38,115,211
Ensembl chr16:38,068,685...38,115,186
JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression ISO Thalidomide analog results in increased expression of NR4A1 mRNA CTD PMID:20525221 NCBI chr15:101,151,783...101,172,676
Ensembl chr15:101,152,150...101,172,676
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Thalidomide analog results in increased expression of NR4A2 mRNA CTD PMID:20525221 NCBI chr 2:56,996,845...57,014,152
Ensembl chr 2:56,996,842...57,014,015
JBrowse link
G Nrp1 neuropilin 1 multiple interactions ISO sphingosine 1-phosphate inhibits the reaction [Thalidomide results in decreased expression of NRP1 mRNA] CTD PMID:15741222 NCBI chr 8:129,085,553...129,231,957
Ensembl chr 8:129,085,085...129,229,844
JBrowse link
G Nrp2 neuropilin 2 multiple interactions ISO sphingosine 1-phosphate inhibits the reaction [Thalidomide results in decreased expression of NRP2 mRNA] CTD PMID:15741222 NCBI chr 1:62,742,476...62,857,851
Ensembl chr 1:62,742,444...62,857,854
JBrowse link
G Nrxn1 neurexin I decreases expression ISO Thalidomide results in decreased expression of NRXN1 mRNA CTD PMID:32756504 NCBI chr17:90,341,072...91,400,587
Ensembl chr17:90,341,059...91,400,499
JBrowse link
G Nt5c3 5'-nucleotidase, cytosolic III decreases expression EXP Thalidomide results in decreased expression of NT5C3 mRNA CTD PMID:26217789 NCBI chr 6:56,859,385...56,900,993
Ensembl chr 6:56,859,385...56,900,917
JBrowse link
G Nt5e 5' nucleotidase, ecto decreases expression EXP Thalidomide results in decreased expression of NT5E mRNA CTD PMID:26217789 NCBI chr 9:88,209,662...88,254,142
Ensembl chr 9:88,209,250...88,254,145
JBrowse link
G Ntan1 N-terminal Asn amidase decreases expression EXP Thalidomide results in decreased expression of NTAN1 mRNA CTD PMID:26217789 NCBI chr16:13,636,629...13,653,314
Ensembl chr16:13,636,709...13,653,315
JBrowse link
G Nudt14 nudix hydrolase 14 decreases expression EXP Thalidomide results in decreased expression of NUDT14 mRNA CTD PMID:26217789 NCBI chr12:112,897,911...112,905,762
Ensembl chr12:112,897,911...112,905,744
JBrowse link
G Nudt22 nudix hydrolase 22 decreases expression EXP Thalidomide results in decreased expression of NUDT22 mRNA CTD PMID:26217789 NCBI chr19:6,970,387...6,973,471
Ensembl chr19:6,970,386...6,973,485
JBrowse link
G Nup62cl nucleoporin 62 C-terminal like decreases expression EXP Thalidomide results in decreased expression of NUP62CL mRNA CTD PMID:26217789 NCBI chr  X:138,907,551...138,963,456
Ensembl chr  X:138,907,554...138,963,461
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of NUSAP1 mRNA CTD PMID:18720364 NCBI chr 2:119,449,205...119,480,646
Ensembl chr 2:119,448,779...119,481,725
JBrowse link
G Oas1g 2'-5' oligoadenylate synthetase 1G decreases expression EXP Thalidomide results in decreased expression of OAS1G mRNA CTD PMID:26217789 NCBI chr 5:121,014,205...121,025,676
Ensembl chr 5:121,014,205...121,025,676
JBrowse link
G Ocln occludin multiple interactions EXP Thalidomide inhibits the reaction [dinitrobenzenesulfonic acid results in decreased expression of OCLN protein] CTD PMID:16680017 NCBI chr13:100,633,012...100,689,226
Ensembl chr13:100,633,015...100,689,226
JBrowse link
G Olig2 oligodendrocyte transcription factor 2 increases expression EXP Thalidomide results in increased expression of OLIG2 mRNA CTD PMID:26217789 NCBI chr16:91,016,745...91,025,567
Ensembl chr16:91,022,345...91,025,565
JBrowse link
G Olig3 oligodendrocyte transcription factor 3 increases expression ISO Thalidomide results in increased expression of OLIG3 mRNA CTD PMID:31711903 NCBI chr10:19,232,287...19,234,352
Ensembl chr10:19,232,281...19,234,352
JBrowse link
G Or10q1 olfactory receptor family 10 subfamily Q member 1 increases expression EXP Thalidomide results in increased expression of OR10Q1 mRNA CTD PMID:26217789 NCBI chr19:13,726,472...13,727,419
Ensembl chr19:13,717,092...13,727,843
JBrowse link
G Or13a27 olfactory receptor family 13 subfamily A member 27 increases expression EXP Thalidomide results in increased expression of OR13A27 mRNA CTD PMID:26217789 NCBI chr 7:139,924,965...139,925,900
Ensembl chr 7:139,923,728...139,941,584
JBrowse link
G Or1d2 olfactory receptor family 1 subfamily D member 2 increases expression EXP Thalidomide results in increased expression of OR1D2 mRNA CTD PMID:26217789 NCBI chr11:74,255,497...74,256,435
Ensembl chr11:74,252,895...74,257,044
JBrowse link
G Or2ag1 olfactory receptor family 2 subfamily AG member 1 increases expression EXP Thalidomide results in increased expression of OR2AG1 mRNA CTD PMID:26217789 NCBI chr 7:106,472,500...106,473,450
Ensembl chr 7:106,471,077...106,476,098
JBrowse link
G Or2y1 olfactory receptor family 2 subfamily Y member 1 increases expression EXP Thalidomide results in increased expression of OR2Y1 mRNA CTD PMID:26217789 NCBI chr11:49,385,362...49,386,291
Ensembl chr11:49,379,897...49,388,323
JBrowse link
G Or2y15 olfactory receptor family 2 subfamily Y member 15 increases expression EXP Thalidomide results in increased expression of OR2Y15 mRNA CTD PMID:26217789 NCBI chr11:49,350,508...49,351,443
Ensembl chr11:49,346,170...49,354,828
JBrowse link
G Or51q1 olfactory receptor family 51 subfamily Q member 1 increases expression EXP Thalidomide results in increased expression of OR51Q1 mRNA CTD PMID:26217789 NCBI chr 7:103,628,383...103,629,348
Ensembl chr 7:103,620,359...103,636,747
JBrowse link
G Or51q1c olfactory receptor family 51 subfamily Q member 1C decreases expression EXP Thalidomide results in decreased expression of OR51Q1C mRNA CTD PMID:26217789 NCBI chr 7:103,652,466...103,653,431
Ensembl chr 7:103,647,953...103,653,564
JBrowse link
G Or52s1b olfactory receptor family 52 subfamily S member 1B increases expression EXP Thalidomide results in increased expression of OR52S1B mRNA CTD PMID:26217789 NCBI chr 7:102,821,898...102,822,842
Ensembl chr 7:102,816,281...102,827,547
JBrowse link
G Or5i1 olfactory receptor family 5 subfamily I member 1 increases expression EXP Thalidomide results in increased expression of OR5I1 mRNA CTD PMID:26217789 NCBI chr 2:87,612,880...87,613,830
Ensembl chr 2:87,609,827...87,614,916
JBrowse link
G Or5p80 olfactory receptor family 5 subfamily P member 80 increases expression EXP Thalidomide results in increased expression of OR5P80 mRNA CTD PMID:26217789 NCBI chr 7:108,229,201...108,230,133
Ensembl chr 7:108,229,201...108,230,835
JBrowse link
G Or5t15 olfactory receptor family 5 subfamily T member 15 increases expression EXP Thalidomide results in increased expression of OR5T15 mRNA CTD PMID:26217789 NCBI chr 2:86,681,114...86,684,664
Ensembl chr 2:86,681,114...86,682,040
JBrowse link
G Or5v1b olfactory receptor family 5 subfamily V member 1B increases expression EXP Thalidomide results in increased expression of OR5V1 mRNA CTD PMID:26217789 NCBI chr17:37,815,851...37,844,816
Ensembl chr17:37,818,921...37,843,340
JBrowse link
G Or6c206 olfactory receptor family 6 subfamily C member 206 increases expression EXP Thalidomide results in increased expression of OR6C206 mRNA CTD PMID:26217789 NCBI chr10:129,096,832...129,097,770
Ensembl chr10:129,094,996...129,100,167
JBrowse link
G Or6c33 olfactory receptor family 6 subfamily C member 33 decreases expression EXP Thalidomide results in decreased expression of OR6C33 mRNA CTD PMID:26217789 NCBI chr10:129,853,232...129,854,170
Ensembl chr10:129,848,490...129,857,155
JBrowse link
G Or7g18 olfactory receptor family 7 subfamily G member 18 increases expression EXP Thalidomide results in increased expression of OR7G18 mRNA CTD PMID:26217789 NCBI chr 9:18,786,256...18,787,572
Ensembl chr 9:18,785,989...18,789,665
JBrowse link
G Or8a1b olfactory receptor family 8 subfamily A member 1B decreases expression EXP Thalidomide results in decreased expression of OR8A1B mRNA CTD PMID:26217789 NCBI chr 9:37,622,644...37,623,576
Ensembl chr 9:37,620,260...37,627,546
JBrowse link
G Or8b3 olfactory receptor family 8 subfamily B member 3 increases expression EXP Thalidomide results in increased expression of OR8B3 mRNA CTD PMID:26217789 NCBI chr 9:38,313,007...38,315,125
Ensembl chr 9:38,312,994...38,319,293
JBrowse link
G Or8b41 olfactory receptor family 8 subfamily B member 41 increases expression EXP Thalidomide results in increased expression of OR8B41 mRNA CTD PMID:26217789 NCBI chr 9:38,054,433...38,055,377
Ensembl chr 9:38,053,813...38,059,671
JBrowse link
G Or8g18 olfactory receptor family 8 subfamily G member 18 decreases expression EXP Thalidomide results in decreased expression of OR8G18 mRNA CTD PMID:26217789 NCBI chr 9:39,148,783...39,149,727
Ensembl chr 9:39,145,708...39,161,290
JBrowse link
G Or9k2b olfactory receptor family 9 subfamily K member 2B increases expression EXP Thalidomide results in increased expression of OR9K2 mRNA CTD PMID:26217789 NCBI chr10:130,015,806...130,016,747
Ensembl chr10:130,014,340...130,020,055
JBrowse link
G Ostf1 osteoclast stimulating factor 1 decreases expression EXP Thalidomide results in decreased expression of OSTF1 mRNA CTD PMID:26217789 NCBI chr19:18,557,728...18,609,177
Ensembl chr19:18,493,501...18,609,187
JBrowse link
G Pabir1 PP2A A alpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 decreases expression EXP Thalidomide results in decreased expression of PABIR1 mRNA CTD PMID:26217789 NCBI chr19:24,451,270...24,454,819
Ensembl chr19:24,453,866...24,454,720
JBrowse link
G Parp1 poly (ADP-ribose) polymerase family, member 1 multiple interactions
increases cleavage
ISO [Curcumin co-treated with Thalidomide] results in increased cleavage of PARP1 protein
Thalidomide analog results in increased cleavage of PARP1 protein
CTD PMID:15858615 PMID:19372569 NCBI chr 1:180,396,456...180,428,564
Ensembl chr 1:180,396,489...180,428,819
JBrowse link
G Pax3 paired box 3 decreases expression ISO Thalidomide results in decreased expression of PAX3 mRNA CTD PMID:31711903 NCBI chr 1:78,077,904...78,173,773
Ensembl chr 1:78,077,904...78,173,771
JBrowse link
G Pax6 paired box 6 increases expression ISO Thalidomide results in increased expression of PAX6 mRNA CTD PMID:31711903 NCBI chr 2:105,499,241...105,528,755
Ensembl chr 2:105,499,245...105,527,709
JBrowse link
G Pdcd10 programmed cell death 10 decreases expression EXP Thalidomide results in decreased expression of PDCD10 mRNA CTD PMID:26217789 NCBI chr 3:75,423,797...75,464,159
Ensembl chr 3:75,423,797...75,464,163
JBrowse link
G Pdlim3 PDZ and LIM domain 3 decreases expression EXP Thalidomide results in decreased expression of PDLIM3 mRNA CTD PMID:26217789 NCBI chr 8:46,338,524...46,372,672
Ensembl chr 8:46,338,498...46,372,585
JBrowse link
G Pecam1 platelet/endothelial cell adhesion molecule 1 decreases expression ISO Thalidomide results in decreased expression of PECAM1 protein CTD PMID:18291259 PMID:34520751 NCBI chr11:106,545,039...106,606,107
Ensembl chr11:106,545,043...106,641,454
JBrowse link
G Pfdn6 prefoldin subunit 6 decreases expression EXP Thalidomide results in decreased expression of PFDN6 mRNA CTD PMID:26217789 NCBI chr17:34,157,883...34,159,317
Ensembl chr17:34,157,795...34,159,317
JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha multiple interactions ISO [ERBB2 protein co-treated with PIK3CA protein mutant form] results in increased susceptibility to Thalidomide metabolite CTD PMID:28745489 NCBI chr 3:32,451,203...32,520,256
Ensembl chr 3:32,451,820...32,522,635
JBrowse link
G Pilra paired immunoglobin-like type 2 receptor alpha decreases expression EXP Thalidomide results in decreased expression of PILRA mRNA CTD PMID:26217789 NCBI chr 5:137,820,214...137,834,540
Ensembl chr 5:137,820,214...137,834,543
JBrowse link
G Pim1 proviral integration site 1 decreases expression ISO Thalidomide results in decreased expression of PIM1 protein CTD PMID:16616857 NCBI chr17:29,709,759...29,715,085
Ensembl chr17:29,709,727...29,715,086
JBrowse link
G Plau plasminogen activator, urokinase decreases expression EXP Thalidomide results in decreased expression of PLAU protein CTD PMID:16288038 NCBI chr14:20,886,730...20,893,456
Ensembl chr14:20,886,728...20,893,453
JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions
decreases expression
ISO
EXP
Thalidomide inhibits the reaction [TGFB1 protein results in increased expression of PLAUR mRNA]; Thalidomide inhibits the reaction [TGFB1 protein results in increased expression of PLAUR protein]
Thalidomide results in decreased expression of PLAUR protein
CTD PMID:16288038 NCBI chr 7:24,161,857...24,175,393
Ensembl chr 7:24,161,909...24,175,393
JBrowse link
G Pltp phospholipid transfer protein decreases expression EXP Thalidomide results in decreased expression of PLTP mRNA CTD PMID:26217789 NCBI chr 2:164,681,441...164,699,564
Ensembl chr 2:164,681,438...164,699,631
JBrowse link
G Polr2k polymerase (RNA) II (DNA directed) polypeptide K decreases expression EXP Thalidomide results in decreased expression of POLR2K mRNA CTD PMID:26217789 NCBI chr15:36,174,156...36,177,158
Ensembl chr15:36,174,156...36,177,156
JBrowse link
G Popdc2 popeye domain containing 2 decreases expression EXP Thalidomide results in decreased expression of POPDC2 mRNA CTD PMID:26217789 NCBI chr16:38,182,523...38,198,578
Ensembl chr16:38,182,571...38,198,578
JBrowse link
G Ppard peroxisome proliferator activator receptor delta increases response to substance ISO PPARD gene SNP results in increased susceptibility to Thalidomide CTD PMID:21245421 NCBI chr17:28,451,715...28,520,446
Ensembl chr17:28,451,674...28,520,448
JBrowse link
G Ppp1r11 protein phosphatase 1, regulatory inhibitor subunit 11 decreases expression EXP Thalidomide results in decreased expression of PPP1R11 mRNA CTD PMID:26217789 NCBI chr17:37,259,247...37,262,684
Ensembl chr17:37,259,248...37,262,633
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO Thalidomide analog results in increased expression of PPP1R15A mRNA CTD PMID:20525221 NCBI chr 7:45,172,341...45,175,692
Ensembl chr 7:45,172,340...45,175,692
JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory inhibitor subunit 1A decreases expression EXP Thalidomide results in decreased expression of PPP1R1A mRNA CTD PMID:26217789 NCBI chr15:103,438,706...103,446,465
Ensembl chr15:103,438,706...103,446,430
JBrowse link
G Prelid2 PRELI domain containing 2 decreases expression EXP Thalidomide results in decreased expression of PRELID2 mRNA CTD PMID:26217789 NCBI chr18:42,008,761...42,084,259
Ensembl chr18:42,008,665...42,084,307
JBrowse link
G Prf1 perforin 1 (pore forming protein) increases expression EXP Thalidomide results in increased expression of PRF1 CTD PMID:17089043 NCBI chr10:61,133,530...61,140,463
Ensembl chr10:61,133,612...61,140,459
JBrowse link
G Prkcd protein kinase C, delta decreases expression ISO Thalidomide results in decreased expression of PRKCD mRNA CTD PMID:32756504 NCBI chr14:30,317,310...30,348,637
Ensembl chr14:30,317,311...30,348,167
JBrowse link
G Prkg1 protein kinase, cGMP-dependent, type I decreases expression EXP Thalidomide results in decreased expression of PRKG1 mRNA CTD PMID:26217789 NCBI chr19:30,541,887...31,742,675
Ensembl chr19:30,541,889...31,742,433
JBrowse link
G Prr5 proline rich 5 (renal) decreases expression EXP Thalidomide results in decreased expression of PRR5 mRNA CTD PMID:26217789 NCBI chr15:84,547,407...84,590,610
Ensembl chr15:84,553,821...84,587,874
JBrowse link
G Prxl2a peroxiredoxin like 2A decreases expression EXP Thalidomide results in decreased expression of PRXL2A mRNA CTD PMID:26217789 NCBI chr14:40,715,692...40,735,790
Ensembl chr14:40,715,697...40,735,745
JBrowse link
G Psme2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) increases expression EXP Thalidomide results in increased expression of PSME2 mRNA CTD PMID:26217789 NCBI chr14:55,824,897...55,828,558
Ensembl chr14:55,824,898...55,828,570
JBrowse link
G Pten phosphatase and tensin homolog increases expression ISO Thalidomide results in increased expression of PTEN protein CTD PMID:19567134 NCBI chr19:32,734,977...32,803,560
Ensembl chr19:32,734,897...32,803,560
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases degradation
decreases expression
multiple interactions
decreases stability
ISO
EXP
Thalidomide results in increased degradation of PTGS2 protein
Thalidomide results in decreased expression of PTGS2 protein
Thalidomide inhibits the reaction [Ifosfamide results in increased expression of PTGS2 protein]
Thalidomide analog inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2]; Thalidomide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Thalidomide inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]
Thalidomide results in decreased stability of PTGS2 mRNA
CTD PMID:11705847 PMID:15982930 PMID:17638016 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978
JBrowse link
G Rab2b RAB2B, member RAS oncogene family decreases expression EXP Thalidomide results in decreased expression of RAB2B mRNA CTD PMID:26006729 PMID:26217789 NCBI chr14:52,499,216...52,516,852
Ensembl chr14:52,499,216...52,517,002
JBrowse link
G Rab8a RAB8A, member RAS oncogene family decreases expression EXP Thalidomide results in decreased expression of RAB8A mRNA CTD PMID:26006729 NCBI chr 8:72,915,044...72,935,210
Ensembl chr 8:72,915,044...72,937,748
JBrowse link
G Rap1b RAS related protein 1b decreases expression EXP Thalidomide results in decreased expression of RAP1B mRNA CTD PMID:26006729 NCBI chr10:117,650,502...117,681,879
Ensembl chr10:117,649,776...117,681,940
JBrowse link
G Rassf9 Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 decreases expression EXP Thalidomide results in decreased expression of RASSF9 mRNA CTD PMID:26217789 NCBI chr10:102,348,083...102,385,598
Ensembl chr10:102,348,083...102,385,597
JBrowse link
G Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) multiple interactions
decreases expression
ISO
EXP
[irinotecan co-treated with Thalidomide co-treated with Celecoxib] results in increased expression of RELA protein; [irinotecan co-treated with Thalidomide] results in increased expression of RELA protein; [resveratrol co-treated with Thalidomide] results in decreased activity of [RELA protein binds to NFKB1 protein]; Thalidomide inhibits the reaction [TNF protein results in increased transport of RELA protein]
[Thalidomide co-treated with Dimethylnitrosamine] results in decreased transport of RELA protein; Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA mRNA]; Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of RELA protein]; Thalidomide inhibits the reaction [TNF protein results in increased expression of RELA mRNA]
Thalidomide results in decreased expression of RELA protein
Thalidomide analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Thalidomide inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein]; Thalidomide inhibits the reaction [Paraquat affects the localization of RELA protein]
CTD PMID:15687330 PMID:16078585 PMID:16333628 PMID:16604421 PMID:16685529 More... NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158
JBrowse link
G Relb avian reticuloendotheliosis viral (v-rel) oncogene related B increases expression ISO Thalidomide analog results in increased expression of RELB mRNA CTD PMID:20525221 NCBI chr 7:19,340,142...19,363,352
Ensembl chr 7:19,340,142...19,363,363
JBrowse link
G Rfc3 replication factor C (activator 1) 3 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of RFC3 mRNA CTD PMID:18720364 NCBI chr 5:151,566,282...151,574,673
Ensembl chr 5:151,566,221...151,574,707
JBrowse link
G Rhoa ras homolog family member A affects expression EXP Thalidomide affects the expression of RHOA mRNA CTD PMID:26006729 NCBI chr 9:108,183,359...108,215,142
Ensembl chr 9:108,183,328...108,215,133
JBrowse link
G Rnase2b ribonuclease, RNase A family, 2B (liver, eosinophil-derived neurotoxin) increases expression EXP Thalidomide results in increased expression of RNASE2B mRNA CTD PMID:26217789 NCBI chr14:51,399,717...51,400,475
Ensembl chr14:51,399,717...51,400,475
JBrowse link
G Rnaseh2c ribonuclease H2, subunit C decreases expression EXP Thalidomide results in decreased expression of RNASEH2C mRNA CTD PMID:26217789 NCBI chr19:5,651,901...5,652,987
Ensembl chr19:5,651,901...5,657,047
JBrowse link
G Rnf138 ring finger protein 138 decreases expression EXP Thalidomide results in decreased expression of RNF138 mRNA CTD PMID:26217789 NCBI chr18:21,134,202...21,161,281
Ensembl chr18:21,134,398...21,161,281
JBrowse link
G Rnf166 ring finger protein 166 multiple interactions ISO Thalidomide results in increased degradation of and results in decreased expression of RNF166 protein CTD PMID:30067223 NCBI chr 8:123,192,884...123,202,813
Ensembl chr 8:123,192,886...123,202,803
JBrowse link
G Rps15 ribosomal protein S15 increases expression EXP Thalidomide results in increased expression of RPS15 mRNA CTD PMID:26217789 NCBI chr10:80,128,265...80,129,948
Ensembl chr10:80,128,287...80,129,948
JBrowse link
G Rps6ka2 ribosomal protein S6 kinase, polypeptide 2 decreases expression EXP Thalidomide results in decreased expression of RPS6KA2 mRNA CTD PMID:26217789 NCBI chr17:7,356,384...7,570,714
Ensembl chr17:7,437,514...7,570,714
JBrowse link
G Rras related RAS viral (r-ras) oncogene decreases expression EXP Thalidomide results in decreased expression of RRAS mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 7:44,665,686...44,671,070
Ensembl chr 7:44,667,385...44,671,071
JBrowse link
G Rrm2 ribonucleotide reductase M2 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of RRM2 mRNA CTD PMID:18720364 NCBI chr12:24,758,253...24,764,145
Ensembl chr12:24,758,240...24,764,145
JBrowse link
G Rtn2 reticulon 2 (Z-band associated protein) decreases expression EXP Thalidomide results in decreased expression of RTN2 mRNA CTD PMID:26217789 NCBI chr 7:19,016,549...19,030,089
Ensembl chr 7:19,016,549...19,030,085
JBrowse link
G Ryr2 ryanodine receptor 2, cardiac decreases expression EXP Thalidomide results in decreased expression of RYR2 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr13:11,567,985...12,121,831
Ensembl chr13:11,567,988...12,121,831
JBrowse link
G Sall4 spalt like transcription factor 4 multiple interactions
increases expression
affects binding
ISO Bortezomib inhibits the reaction [Thalidomide results in increased degradation of and results in decreased expression of SALL4 protein]; pevonedistat inhibits the reaction [Thalidomide results in increased degradation of and results in decreased expression of SALL4 protein]; TAK-243 inhibits the reaction [Thalidomide results in increased degradation of and results in decreased expression of SALL4 protein]; Thalidomide results in increased degradation of and results in decreased expression of SALL4 protein
Thalidomide results in increased expression of SALL4 mRNA
Thalidomide binds to [SALL4 protein binds to CRBN protein]
CTD PMID:30067223 NCBI chr 2:168,590,252...168,609,121
Ensembl chr 2:168,590,252...168,609,863
JBrowse link
G Sap30 sin3 associated polypeptide decreases expression EXP Thalidomide results in decreased expression of SAP30 mRNA CTD PMID:26217789 NCBI chr 8:57,935,740...57,940,874
Ensembl chr 8:57,935,741...57,940,894
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 decreases expression EXP Thalidomide results in decreased expression of SAT1 mRNA CTD PMID:26217789 NCBI chr  X:153,996,128...153,999,345
Ensembl chr  X:153,996,128...153,999,445
JBrowse link
G Scn7a sodium channel, voltage-gated, type VII, alpha decreases expression EXP Thalidomide results in decreased expression of SCN7A mRNA CTD PMID:26217789 NCBI chr 2:66,503,770...66,615,254
Ensembl chr 2:66,503,769...66,615,258
JBrowse link
G Sdhaf1 succinate dehydrogenase complex assembly factor 1 decreases expression EXP Thalidomide results in decreased expression of SDHAF1 mRNA CTD PMID:26217789 NCBI chr 7:30,020,834...30,021,800
Ensembl chr 7:30,020,831...30,023,320
JBrowse link
G Sdhc succinate dehydrogenase complex, subunit C, integral membrane protein decreases expression EXP Thalidomide results in decreased expression of SDHC mRNA CTD PMID:26217789 NCBI chr 1:170,956,726...170,978,209
Ensembl chr 1:170,954,734...170,978,172
JBrowse link
G Selenos selenoprotein S decreases expression EXP Thalidomide results in decreased expression of SELENOS mRNA CTD PMID:26006729 NCBI chr 7:65,729,397...65,739,153
Ensembl chr 7:65,729,397...65,739,153
JBrowse link
G Sell selectin, lymphocyte decreases expression ISO Thalidomide results in decreased expression of SELL protein CTD PMID:16344495 NCBI chr 1:163,889,556...163,908,354
Ensembl chr 1:163,889,551...163,911,750
JBrowse link
G Serpinb2 serine (or cysteine) peptidase inhibitor, clade B, member 2 increases response to substance ISO SERPINB2 gene SNP results in increased susceptibility to Thalidomide CTD PMID:21245421 NCBI chr 1:107,439,153...107,453,330
Ensembl chr 1:107,439,153...107,463,208
JBrowse link
G Serpinb6c serine (or cysteine) peptidase inhibitor, clade B, member 6c increases expression EXP Thalidomide results in increased expression of SERPINB6C mRNA CTD PMID:26217789 NCBI chr13:34,063,799...34,089,709
Ensembl chr13:34,063,799...34,089,691
JBrowse link
G Sfrp2 secreted frizzled-related protein 2 increases expression EXP Thalidomide results in increased expression of SFRP2 mRNA CTD PMID:26217789 NCBI chr 3:83,673,628...83,681,621
Ensembl chr 3:83,673,628...83,681,623
JBrowse link
G Sh3bgr SH3-binding domain glutamic acid-rich protein decreases expression EXP Thalidomide results in decreased expression of SH3BGR mRNA CTD PMID:26217789 NCBI chr16:96,001,670...96,030,133
Ensembl chr16:96,001,650...96,030,135
JBrowse link
G Slc12a6 solute carrier family 12, member 6 increases response to substance ISO SLC12A6 gene SNP results in increased susceptibility to Thalidomide CTD PMID:21245421 NCBI chr 2:112,096,659...112,193,508
Ensembl chr 2:112,096,170...112,193,508
JBrowse link
G Slc13a4 solute carrier family 13 (sodium/sulfate symporters), member 4 decreases expression EXP Thalidomide results in decreased expression of SLC13A4 mRNA CTD PMID:26217789 NCBI chr 6:35,244,888...35,285,061
Ensembl chr 6:35,244,892...35,285,066
JBrowse link
G Slc22a2 solute carrier family 22 (organic cation transporter), member 2 multiple interactions ISO Thalidomide inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr17:12,803,076...12,847,376
Ensembl chr17:12,803,019...12,847,375
JBrowse link
G Slc25a20 solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20 decreases expression EXP Thalidomide results in decreased expression of SLC25A20 mRNA CTD PMID:26217789 NCBI chr 9:108,539,335...108,561,841
Ensembl chr 9:108,539,287...108,561,840
JBrowse link
G Slc25a30 solute carrier family 25, member 30 decreases expression EXP Thalidomide results in decreased expression of SLC25A30 mRNA CTD PMID:26217789 NCBI chr14:75,994,986...76,024,477
Ensembl chr14:75,997,557...76,024,477
JBrowse link
G Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 increases expression EXP Thalidomide results in increased expression of SLC2A3 mRNA CTD PMID:26217789 NCBI chr 6:122,704,783...122,779,149
Ensembl chr 6:122,704,768...122,778,599
JBrowse link
G Slc44a3 solute carrier family 44, member 3 decreases expression EXP Thalidomide results in decreased expression of SLC44A3 mRNA CTD PMID:26217789 NCBI chr 3:121,253,177...121,325,993
Ensembl chr 3:121,253,177...121,326,053
JBrowse link
G Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 decreases expression EXP Thalidomide results in decreased expression of SLC8A1 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr17:81,680,534...82,045,816
Ensembl chr17:81,680,534...82,045,806
JBrowse link
G Slco4c1 solute carrier organic anion transporter family, member 4C1 decreases expression EXP Thalidomide results in decreased expression of SLCO4C1 mRNA CTD PMID:26217789 NCBI chr 1:96,744,918...96,800,027
Ensembl chr 1:96,743,995...96,799,896
JBrowse link
G Smpd2 sphingomyelin phosphodiesterase 2, neutral multiple interactions ISO sphingosine 1-phosphate inhibits the reaction [Thalidomide results in increased activity of SMPD2 protein] CTD PMID:15741222 NCBI chr10:41,363,168...41,366,410
Ensembl chr10:41,361,638...41,366,365
JBrowse link
G Smyd1 SET and MYND domain containing 1 decreases expression EXP Thalidomide results in decreased expression of SMYD1 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 6:71,190,924...71,239,265
Ensembl chr 6:71,190,924...71,299,217
JBrowse link
G Snap25 synaptosomal-associated protein 25 increases expression ISO Thalidomide results in increased expression of SNAP25 mRNA; Thalidomide results in increased expression of SNAP25 protein CTD PMID:27693314 NCBI chr 2:136,555,359...136,624,348
Ensembl chr 2:136,555,373...136,624,348
JBrowse link
G Snord104 small nucleolar RNA, C/D box 104 increases expression EXP Thalidomide results in increased expression of SNORD104 mRNA CTD PMID:26217789 NCBI chr11:106,391,817...106,391,889
Ensembl chr11:106,391,819...106,391,888
JBrowse link
G Snord111 small nucleolar RNA, C/D box 111 increases expression EXP Thalidomide results in increased expression of SNORD111 mRNA CTD PMID:26217789 NCBI chr 8:111,565,167...111,565,230
Ensembl chr 8:111,565,160...111,565,248
JBrowse link
G Snord123 small nucleolar RNA, C/D box 123 increases expression EXP Thalidomide results in increased expression of SNORD123 mRNA CTD PMID:26217789 NCBI chr15:32,241,991...32,242,078
Ensembl chr15:32,241,999...32,242,069
JBrowse link
G Snrpd1 small nuclear ribonucleoprotein D1 decreases expression EXP Thalidomide results in decreased expression of SNRPD1 mRNA CTD PMID:26217789 NCBI chr18:10,617,796...10,628,230
Ensembl chr18:10,617,775...10,642,079
JBrowse link
G Snx16 sorting nexin 16 increases expression ISO Thalidomide analog results in increased expression of SNX16 mRNA CTD PMID:20525221 NCBI chr 3:10,482,877...10,505,194
Ensembl chr 3:10,482,877...10,505,162
JBrowse link
G Snx24 sorting nexing 24 decreases expression EXP Thalidomide results in decreased expression of SNX24 mRNA CTD PMID:26217789 NCBI chr18:53,376,877...53,523,994
Ensembl chr18:53,378,734...53,523,992
JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions EXP
ISO
Thalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of FASL mRNA]; Thalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of IL12B mRNA]; Thalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of TNF mRNA]; Thalidomide promotes the reaction [SOD1 gene mutant form results in increased expression of IL1RN mRNA]; Thalidomide promotes the reaction [SOD1 gene mutant form results in increased expression of TGFB1 mRNA]
Thalidomide inhibits the reaction [Carbon Tetrachloride results in decreased activity of SOD1 protein]
CTD PMID:16510725 PMID:17030452 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217
JBrowse link
G Sox1 SRY (sex determining region Y)-box 1 decreases expression EXP Thalidomide results in decreased expression of SOX1 mRNA CTD PMID:26217789 NCBI chr 8:12,445,519...12,449,555
Ensembl chr 8:12,445,295...12,450,126
JBrowse link
G Sox17 SRY (sex determining region Y)-box 17 decreases localization ISO Thalidomide results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 1:4,561,154...4,567,624
Ensembl chr 1:4,561,154...4,567,577
JBrowse link
G Sp1 trans-acting transcription factor 1 decreases activity ISO Thalidomide results in decreased activity of SP1 protein CTD PMID:10533722 NCBI chr15:102,314,751...102,344,839
Ensembl chr15:102,314,578...102,344,839
JBrowse link
G Sp5 trans-acting transcription factor 5 decreases expression EXP Thalidomide results in decreased expression of SP5 mRNA CTD PMID:26217789 NCBI chr 2:70,305,267...70,308,070
Ensembl chr 2:70,305,267...70,308,073
JBrowse link
G Spa17 sperm autoantigenic protein 17 decreases expression EXP Thalidomide results in decreased expression of SPA17 mRNA CTD PMID:26217789 NCBI chr 9:37,514,590...37,525,018
Ensembl chr 9:37,514,586...37,525,018
JBrowse link
G Spag5 sperm associated antigen 5 multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of SPAG5 mRNA CTD PMID:18720364 NCBI chr11:78,192,412...78,213,283
Ensembl chr11:78,192,355...78,213,283
JBrowse link
G Sphkap SPHK1 interactor, AKAP domain containing decreases expression EXP Thalidomide results in decreased expression of SPHKAP mRNA CTD PMID:26217789 NCBI chr 1:83,233,163...83,385,853
Ensembl chr 1:83,231,860...83,385,921
JBrowse link
G Srrd SRR1 domain containing decreases expression EXP Thalidomide results in decreased expression of SRRD mRNA CTD PMID:26217789 NCBI chr 5:112,485,257...112,490,921
Ensembl chr 5:112,485,258...112,490,906
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation
multiple interactions
ISO Thalidomide analog results in decreased phosphorylation of STAT3 protein
[resveratrol co-treated with Thalidomide] results in decreased phosphorylation of STAT3 protein; Thalidomide promotes the reaction [Capsaicin results in decreased phosphorylation of and results in decreased activity of STAT3 protein]
CTD PMID:15858615 PMID:17164350 PMID:17505005 NCBI chr11:100,777,632...100,830,447
Ensembl chr11:100,775,924...100,830,366
JBrowse link
G Stmn2 stathmin-like 2 decreases expression EXP Thalidomide results in decreased expression of STMN2 mRNA CTD PMID:26217789 NCBI chr 3:8,574,587...8,626,664
Ensembl chr 3:8,574,420...8,626,666
JBrowse link
G Swsap1 SWIM type zinc finger 7 associated protein 1 decreases expression EXP Thalidomide results in decreased expression of SWSAP1 mRNA CTD PMID:26217789 NCBI chr 9:21,867,049...21,869,566
Ensembl chr 9:21,867,051...21,869,560
JBrowse link
G Synj2bp synaptojanin 2 binding protein decreases expression EXP Thalidomide results in decreased expression of SYNJ2BP mRNA CTD PMID:26006729 NCBI chr12:81,538,968...81,579,685
Ensembl chr12:81,544,715...81,579,685
JBrowse link
G Syt15 synaptotagmin XV decreases expression ISO Thalidomide results in decreased expression of SYT15 mRNA CTD PMID:32756504 NCBI chr14:33,941,915...33,952,378
Ensembl chr14:33,941,552...33,952,377
JBrowse link
G Syt4 synaptotagmin IV increases expression ISO Thalidomide results in increased expression of SYT4 mRNA CTD PMID:32756504 NCBI chr18:31,570,861...31,580,468
Ensembl chr18:31,570,861...31,580,459
JBrowse link
G Tc2n tandem C2 domains, nuclear decreases expression EXP Thalidomide results in decreased expression of TC2N mRNA CTD PMID:26217789 NCBI chr12:101,611,705...101,685,178
Ensembl chr12:101,611,702...101,684,782
JBrowse link
G Tcf15 transcription factor 15 decreases expression ISO Thalidomide results in decreased expression of TCF15 mRNA CTD PMID:31711903 NCBI chr 2:151,984,973...151,991,017
Ensembl chr 2:151,985,481...151,991,017
JBrowse link
G Tdg thymine DNA glycosylase decreases expression EXP Thalidomide results in decreased expression of TDG mRNA CTD PMID:26217789 NCBI chr10:82,465,649...82,486,633
Ensembl chr10:82,465,662...82,486,633
JBrowse link
G Tefm transcription elongation factor, mitochondrial decreases expression EXP Thalidomide results in decreased expression of TEFM mRNA CTD PMID:26217789 NCBI chr11:80,027,500...80,033,697
Ensembl chr11:80,027,504...80,033,001
JBrowse link
G Tek TEK receptor tyrosine kinase decreases expression ISO Thalidomide results in decreased expression of TEK mRNA CTD PMID:15618473 NCBI chr 4:94,627,322...94,763,213
Ensembl chr 4:94,627,526...94,763,213
JBrowse link
G Tex16 testis expressed gene 16 decreases expression EXP Thalidomide results in decreased expression of TEX16 mRNA CTD PMID:26217789 NCBI chr  X:110,804,655...111,159,053
Ensembl chr  X:111,148,746...111,153,549
Ensembl chr  X:111,148,746...111,153,549
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
decreases expression
ISO
EXP
Thalidomide inhibits the reaction [TGFB1 protein results in increased degradation of NFKBIA protein]; Thalidomide inhibits the reaction [TGFB1 protein results in increased expression of PLAUR mRNA]; Thalidomide inhibits the reaction [TGFB1 protein results in increased expression of PLAUR protein]; Thalidomide inhibits the reaction [TGFB1 protein results in increased phosphorylation of NFKBIA protein]; Thalidomide inhibits the reaction [TGFB1 protein results in increased transport of NFKBIA protein]
Thalidomide promotes the reaction [SOD1 gene mutant form results in increased expression of TGFB1 mRNA]
Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]; Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; Thalidomide inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Thalidomide inhibits the reaction [Thioacetamide results in increased expression of TGFB1 mRNA]
Thalidomide results in decreased expression of TGFB1 mRNA; Thalidomide results in decreased expression of TGFB1 protein
CTD PMID:15464241 PMID:16288038 PMID:16510725 PMID:16549389 PMID:16604421 More... NCBI chr 7:25,386,406...25,404,503
Ensembl chr 7:25,386,427...25,404,502
JBrowse link
G Tgfbi transforming growth factor, beta induced decreases expression EXP Thalidomide results in decreased expression of TGFBI mRNA CTD PMID:26006729 PMID:26217789 NCBI chr13:56,757,399...56,787,172
Ensembl chr13:56,757,336...56,787,375
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor I decreases expression ISO Thalidomide results in decreased expression of TGFBR1 mRNA; Thalidomide results in decreased expression of TGFBR1 protein CTD PMID:15618473 NCBI chr 4:47,353,258...47,414,926
Ensembl chr 4:47,353,222...47,414,931
JBrowse link
G Timp1 tissue inhibitor of metalloproteinase 1 multiple interactions ISO Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA]; Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein]; Thalidomide inhibits the reaction [Thioacetamide results in increased expression of TIMP1 mRNA] CTD PMID:15464241 PMID:17030452 NCBI chr  X:20,736,524...20,740,972
Ensembl chr  X:20,736,405...20,740,974
JBrowse link
G Timp2 tissue inhibitor of metalloproteinase 2 multiple interactions ISO Thalidomide inhibits the reaction [Thioacetamide results in increased expression of TIMP2 mRNA] CTD PMID:15464241 NCBI chr11:118,191,887...118,246,237
Ensembl chr11:118,191,887...118,246,566
JBrowse link
G Tinagl1 tubulointerstitial nephritis antigen-like 1 decreases expression EXP Thalidomide results in decreased expression of TINAGL1 mRNA CTD PMID:26217789 NCBI chr 4:130,059,393...130,068,915
Ensembl chr 4:130,058,247...130,068,915
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP Thalidomide inhibits the reaction [dinitrobenzenesulfonic acid results in decreased expression of TJP1 protein] CTD PMID:16680017 NCBI chr 7:64,945,913...65,177,629
Ensembl chr 7:64,945,913...65,177,529
JBrowse link
G Tm2d3 TM2 domain containing 3 decreases expression EXP Thalidomide results in decreased expression of TM2D3 mRNA CTD PMID:26217789 NCBI chr 7:65,343,204...65,351,650
Ensembl chr 7:65,340,917...65,351,661
JBrowse link
G Tmem138 transmembrane protein 138 decreases expression EXP Thalidomide results in decreased expression of TMEM138 mRNA CTD PMID:26217789 NCBI chr19:10,547,842...10,554,765
Ensembl chr19:10,547,842...10,554,726
JBrowse link
G Tmem176a transmembrane protein 176A decreases expression EXP Thalidomide results in decreased expression of TMEM176A mRNA CTD PMID:26217789 NCBI chr 6:48,818,417...48,822,298
Ensembl chr 6:48,817,853...48,824,005
JBrowse link
G Tmpo thymopoietin multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TMPO mRNA CTD PMID:18720364 NCBI chr10:90,983,433...91,017,614
Ensembl chr10:90,983,433...91,017,177
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
decreases expression
increases degradation
ISO
EXP
Thalidomide analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Thalidomide inhibits the reaction [Endotoxins results in increased expression of TNF protein]; Thalidomide inhibits the reaction [lipophosphonoglycan results in increased secretion of TNF protein]; Thalidomide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Thalidomide inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Thalidomide inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Thalidomide inhibits the reaction [TNF protein results in increased expression of CXCL8 protein]; Thalidomide inhibits the reaction [TNF protein results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Thalidomide inhibits the reaction [TNF protein results in increased transport of RELA protein]
Thalidomide analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Thalidomide inhibits the reaction [[Ethanol co-treated with Hydrochloric Acid] results in increased expression of TNF protein]; Thalidomide inhibits the reaction [dinitrobenzenesulfonic acid results in increased expression of TNF protein]; Thalidomide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [SOD1 gene mutant form results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [Zymosan results in increased expression of TNF mRNA]; TNF protein affects the reaction [vadimezan affects the metabolism of Thalidomide]
Thalidomide results in increased expression of TNF protein
Thalidomide results in decreased expression of TNF mRNA
Thalidomide inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Thalidomide inhibits the reaction [Dimethylnitrosamine results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [irinotecan results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [irinotecan results in increased expression of TNF protein]; Thalidomide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [Paraquat results in increased expression of TNF protein]; Thalidomide inhibits the reaction [Thioacetamide results in increased expression of TNF mRNA]; Thalidomide inhibits the reaction [TNF protein results in increased expression of CHUK protein]; Thalidomide inhibits the reaction [TNF protein results in increased expression of COL1A2 mRNA]; Thalidomide inhibits the reaction [TNF protein results in increased expression of RELA mRNA]; Thalidomide inhibits the reaction [TNF protein results in increased phosphorylation of NFKBIA protein]; Thalidomide inhibits the reaction [Zymosan results in increased expression of TNF protein]
Thalidomide results in increased expression of TNF mRNA
Thalidomide results in increased degradation of TNF mRNA
Thalidomide results in decreased expression of TNF mRNA; Thalidomide results in decreased expression of TNF protein
CTD PMID:9068814 PMID:9623511 PMID:10496904 PMID:10720640 PMID:11367517 More... NCBI chr17:35,418,343...35,420,983
Ensembl chr17:35,418,357...35,420,983
JBrowse link
G Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b decreases expression ISO Thalidomide results in decreased expression of TNFRSF10A protein CTD PMID:16531263 NCBI chr14:70,004,921...70,021,860
Ensembl chr14:70,004,921...70,021,860
JBrowse link
G Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a decreases expression ISO Thalidomide results in decreased expression of TNFRSF1A mRNA; Thalidomide results in decreased expression of TNFRSF1A protein CTD PMID:15618473 PMID:16344495 NCBI chr 6:125,326,686...125,339,446
Ensembl chr 6:125,326,325...125,339,447
JBrowse link
G Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b decreases expression ISO Thalidomide results in decreased expression of TNFRSF1B mRNA CTD PMID:15618473 NCBI chr 4:144,938,938...144,973,453
Ensembl chr 4:144,940,033...144,973,440
JBrowse link
G Tnfsf10 tumor necrosis factor (ligand) superfamily, member 10 decreases expression ISO Thalidomide results in decreased expression of TNFSF10 protein CTD PMID:16531263 NCBI chr 3:27,371,226...27,393,814
Ensembl chr 3:27,371,177...27,396,576
JBrowse link
G Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 multiple interactions ISO [Thalidomide co-treated with Dexamethasone] results in decreased expression of TNFSF11 protein CTD PMID:16079895 NCBI chr14:78,514,886...78,545,483
Ensembl chr14:78,514,885...78,545,483
JBrowse link
G Tnnc1 troponin C, cardiac/slow skeletal decreases expression EXP Thalidomide results in decreased expression of TNNC1 mRNA CTD PMID:26006729 PMID:26217789 NCBI chr14:30,930,274...30,933,671
Ensembl chr14:30,930,269...30,933,686
JBrowse link
G Top2a topoisomerase (DNA) II alpha multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TOP2A mRNA CTD PMID:18720364 NCBI chr11:98,883,773...98,915,037
Ensembl chr11:98,883,769...98,915,015
JBrowse link
G Tram1l1 translocation associated membrane protein 1-like 1 decreases expression EXP Thalidomide results in decreased expression of TRAM1L1 mRNA CTD PMID:26217789 NCBI chr 3:124,114,686...124,116,909
Ensembl chr 3:124,114,504...124,118,392
JBrowse link
G Trappc2l trafficking protein particle complex 2L decreases expression EXP Thalidomide results in decreased expression of TRAPPC2L mRNA CTD PMID:26217789 NCBI chr 8:123,338,365...123,342,330
Ensembl chr 8:123,338,379...123,343,399
JBrowse link
G Trav7-4 T cell receptor alpha variable 7-4 decreases expression EXP Thalidomide results in decreased expression of TRAV7-4 mRNA CTD PMID:26217789 NCBI chr14:53,698,666...53,699,195
Ensembl chr14:53,698,556...53,699,195
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Thalidomide analog results in increased expression of TRIB3 mRNA CTD PMID:20525221 NCBI chr 2:152,179,345...152,185,980
Ensembl chr 2:152,179,342...152,185,952
JBrowse link
G Trim55 tripartite motif-containing 55 decreases expression EXP Thalidomide results in decreased expression of TRIM55 mRNA CTD PMID:26217789 NCBI chr 3:19,698,591...19,746,748
Ensembl chr 3:19,698,638...19,746,585
JBrowse link
G Trp53 transformation related protein 53 increases expression ISO Thalidomide analog results in increased expression of TP53 mRNA CTD PMID:20525221 NCBI chr11:69,471,174...69,482,699
Ensembl chr11:69,471,185...69,482,699
JBrowse link
G Tspan33 tetraspanin 33 decreases expression EXP Thalidomide results in decreased expression of TSPAN33 mRNA CTD PMID:26217789 NCBI chr 6:29,694,213...29,718,557
Ensembl chr 6:29,694,221...29,718,558
JBrowse link
G Ttc32 tetratricopeptide repeat domain 32 decreases expression EXP Thalidomide results in decreased expression of TTC32 mRNA CTD PMID:26217789 NCBI chr12:9,079,997...9,086,394
Ensembl chr12:9,079,997...9,091,988
JBrowse link
G Ttk Ttk protein kinase multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of TTK mRNA CTD PMID:18720364 NCBI chr 9:83,716,704...83,754,442
Ensembl chr 9:83,716,742...83,754,442
JBrowse link
G Ttn titin decreases expression EXP Thalidomide results in decreased expression of TTN mRNA CTD PMID:26006729 PMID:26217789 NCBI chr 2:76,534,324...76,812,901
Ensembl chr 2:76,534,324...76,812,891
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C multiple interactions ISO [Azacitidine co-treated with Thalidomide] affects the expression of UBE2C mRNA CTD PMID:18720364 NCBI chr 2:164,611,849...164,614,822
Ensembl chr 2:164,611,818...164,620,742
JBrowse link
G Ubxn1 UBX domain protein 1 decreases expression EXP Thalidomide results in decreased expression of UBXN1 mRNA CTD PMID:26217789 NCBI chr19:8,848,912...8,853,030
Ensembl chr19:8,848,860...8,853,227
JBrowse link
G Uchl3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) decreases expression EXP Thalidomide results in decreased expression of UCHL3 mRNA CTD PMID:26217789 NCBI chr14:101,891,387...101,933,561
Ensembl chr14:101,891,403...101,933,561
JBrowse link
G Uchl4 ubiquitin carboxyl-terminal esterase L4 decreases expression EXP Thalidomide results in decreased expression of UCHL4 mRNA CTD PMID:26217789 NCBI chr 9:64,142,483...64,143,644
Ensembl chr 9:64,142,483...64,143,644
JBrowse link
G Ugt2b37 UDP glucuronosyltransferase 2 family, polypeptide B37 increases expression EXP Thalidomide results in increased expression of UGT2B37 mRNA CTD PMID:26217789 NCBI chr 5:87,388,351...87,402,647
Ensembl chr 5:87,388,352...87,402,663
JBrowse link
G Uncx UNC homeobox decreases expression ISO Thalidomide results in decreased expression of UNCX mRNA CTD PMID:31711903 NCBI chr 5:139,529,620...139,533,934
Ensembl chr 5:139,529,249...139,533,934
JBrowse link
G Upp1 uridine phosphorylase 1 decreases expression EXP Thalidomide results in decreased expression of UPP1 mRNA CTD PMID:26217789 NCBI chr11:9,068,008...9,086,170
Ensembl chr11:9,068,103...9,086,170
JBrowse link
G Uqcc5 ubiquinol-cytochrome c reductase complex assembly factor 5 decreases expression EXP Thalidomide results in decreased expression of UQCC5 mRNA CTD PMID:26217789 NCBI chr14:30,810,081...30,850,894
Ensembl chr14:30,810,089...30,850,913
JBrowse link
G Usp17le ubiquitin specific peptidase 17-like E increases expression EXP Thalidomide results in increased expression of USP17LE mRNA CTD PMID:26217789 NCBI chr 7:104,417,168...104,426,677
Ensembl chr 7:104,417,256...104,426,677
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression ISO Thalidomide results in decreased expression of VCAM1 mRNA; Thalidomide results in decreased expression of VCAM1 protein CTD PMID:17174718 NCBI chr 3:115,903,669...115,923,337
Ensembl chr 3:115,903,598...115,923,337
JBrowse link
G Vegfa vascular endothelial growth factor A affects expression
affects secretion
decreases secretion
decreases activity
decreases expression
increases expression
multiple interactions
ISO
EXP
Thalidomide affects the expression of VEGFA mRNA; Thalidomide affects the expression of VEGFA protein
Thalidomide affects the secretion of VEGFA protein
Thalidomide analog results in decreased secretion of VEGFA protein
Thalidomide results in decreased activity of VEGFA protein
Thalidomide results in decreased expression of VEGFA mRNA; Thalidomide results in decreased expression of VEGFA protein
Thalidomide results in increased expression of VEGFA protein
[Thalidomide co-treated with Paclitaxel] results in decreased expression of VEGFA mRNA
[temozolomide co-treated with Thalidomide] results in decreased expression of VEGFA protein
[Arsenic Trioxide co-treated with Thalidomide] results in decreased expression of VEGFA mRNA; FGD5-AS1 inhibits the reaction [Thalidomide results in decreased expression of and results in decreased secretion of VEGFA protein]; Thalidomide results in decreased expression of and results in decreased secretion of VEGFA protein
CTD PMID:15858615 PMID:15863203 PMID:15939924 PMID:15982930 PMID:16313753 More... NCBI chr17:46,327,919...46,343,303
Ensembl chr17:46,327,919...46,343,295
JBrowse link
G Vegfb vascular endothelial growth factor B multiple interactions
decreases expression
ISO [Arsenic Trioxide co-treated with Thalidomide] results in decreased expression of VEGFB mRNA
Thalidomide results in decreased expression of VEGFB mRNA
CTD PMID:29699374 NCBI chr19:6,959,840...6,965,019
Ensembl chr19:6,959,841...6,965,019
JBrowse link
G Vegfc vascular endothelial growth factor C affects expression ISO Thalidomide affects the expression of VEGFC mRNA CTD PMID:29699374 NCBI chr 8:54,530,567...54,639,489
Ensembl chr 8:54,530,641...54,640,131
JBrowse link
G Vegfd vascular endothelial growth factor D decreases expression
multiple interactions
ISO Thalidomide results in decreased expression of VEGFD mRNA
[Arsenic Trioxide co-treated with Thalidomide] results in decreased expression of VEGFD mRNA
CTD PMID:29699374 NCBI chr  X:163,156,282...163,185,643
Ensembl chr  X:163,156,374...163,185,646
JBrowse link
G Vmn1r27 vomeronasal 1 receptor 27 increases expression EXP Thalidomide results in increased expression of VMN1R27 mRNA CTD PMID:26217789 NCBI chr 6:58,192,091...58,193,002
Ensembl chr 6:58,190,076...58,195,806
JBrowse link
G Vmn1r80 vomeronasal 1 receptor 80 increases expression EXP Thalidomide results in increased expression of VMN1R80 mRNA CTD PMID:26217789 NCBI chr 7:11,926,892...11,927,818
Ensembl chr 7:11,923,213...11,937,240
JBrowse link
G Vmn2r20 vomeronasal 2, receptor 20 decreases expression EXP Thalidomide results in decreased expression of VMN2R20 mRNA CTD PMID:26217789 NCBI chr 6:123,362,221...123,395,020
Ensembl chr 6:123,350,472...123,395,075
JBrowse link
G Vtn vitronectin decreases expression EXP Thalidomide results in decreased expression of VTN mRNA CTD PMID:26217789 NCBI chr11:78,389,946...78,393,151
Ensembl chr11:78,389,917...78,393,150
JBrowse link
G Wnt5b wingless-type MMTV integration site family, member 5B decreases expression ISO Thalidomide results in decreased expression of WNT5B mRNA CTD PMID:24154490 NCBI chr 6:119,409,493...119,521,847
Ensembl chr 6:119,409,492...119,521,308
JBrowse link
G Wnt8a wingless-type MMTV integration site family, member 8A decreases expression EXP Thalidomide results in decreased expression of WNT8A mRNA CTD PMID:26217789 NCBI chr18:34,675,380...34,681,114
Ensembl chr18:34,675,366...34,681,326
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO Thalidomide analog results in decreased expression of XIAP protein CTD PMID:15858615 NCBI chr  X:41,148,483...41,198,541
Ensembl chr  X:41,148,556...41,198,533
JBrowse link
G Xlr3b X-linked lymphocyte-regulated 3B increases expression EXP Thalidomide results in increased expression of XLR3B mRNA CTD PMID:26217789 NCBI chr  X:72,235,817...72,246,927
Ensembl chr  X:72,235,813...72,246,536
JBrowse link
G Yju2b YJU2 splicing factor homolog B decreases expression EXP Thalidomide results in decreased expression of YJU2B mRNA CTD PMID:26217789 NCBI chr 8:84,984,396...84,997,087
Ensembl chr 8:84,984,424...84,997,009
JBrowse link
G Zcchc17 zinc finger, CCHC domain containing 17 increases expression EXP Thalidomide results in increased expression of ZCCHC17 mRNA CTD PMID:26217789 NCBI chr 4:130,209,176...130,253,785
Ensembl chr 4:130,209,176...130,253,736
JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 multiple interactions
decreases expression
ISO FGD5-AS1 inhibits the reaction [Thalidomide results in decreased expression of ZEB1 protein] CTD PMID:34520751 NCBI chr18:5,591,330...5,775,468
Ensembl chr18:5,591,860...5,775,467
JBrowse link
G Zfp119b zinc finger protein 119b decreases expression EXP Thalidomide results in decreased expression of ZFP119B mRNA CTD PMID:26217789 NCBI chr17:56,245,373...56,263,186
Ensembl chr17:56,245,381...56,256,500
JBrowse link
G Zfp273 zinc finger protein 273 decreases expression EXP Thalidomide results in decreased expression of ZFP273 mRNA CTD PMID:26217789 NCBI chr13:67,961,935...67,975,119
Ensembl chr13:67,961,859...67,975,121
JBrowse link
G Zfp692 zinc finger protein 692 multiple interactions ISO Thalidomide results in increased degradation of and results in decreased expression of ZNF692 protein CTD PMID:30067223 NCBI chr11:58,197,883...58,205,971
Ensembl chr11:58,197,895...58,205,453
JBrowse link
G Zfp747 zinc finger protein 747 decreases expression EXP Thalidomide results in decreased expression of ZFP747 mRNA CTD PMID:26217789 NCBI chr 7:126,971,709...126,975,222
Ensembl chr 7:126,971,709...126,975,222
JBrowse link
G Zfp758 zinc finger protein 758 decreases expression EXP Thalidomide results in decreased expression of ZFP758 mRNA CTD PMID:26217789 NCBI chr17:22,580,406...22,612,890
Ensembl chr17:22,580,434...22,596,262
JBrowse link
G Zfp780b zinc finger protein 780B decreases expression EXP Thalidomide results in decreased expression of ZFP780B mRNA CTD PMID:26217789 NCBI chr 7:27,658,560...27,678,768
Ensembl chr 7:27,658,560...27,678,596
JBrowse link
G Zfp820 zinc finger protein 820 decreases expression EXP Thalidomide results in decreased expression of ZFP820 mRNA CTD PMID:26217789 NCBI chr17:22,035,857...22,064,740
Ensembl chr17:22,035,866...22,064,753
JBrowse link
G Zfp953 zinc finger protein 953 decreases expression EXP Thalidomide results in decreased expression of ZFP953 mRNA CTD PMID:26217789 NCBI chr13:67,487,373...67,508,691
Ensembl chr13:67,487,370...67,508,724
JBrowse link
G Zfpl1 zinc finger like protein 1 decreases expression EXP Thalidomide results in decreased expression of ZFPL1 mRNA CTD PMID:26217789 NCBI chr19:6,130,792...6,134,961
Ensembl chr19:6,130,792...6,134,986
JBrowse link
G Zim1 zinc finger, imprinted 1 decreases expression EXP Thalidomide results in decreased expression of ZIM1 mRNA CTD PMID:26217789 NCBI chr 7:6,677,443...6,699,521
Ensembl chr 7:6,674,268...6,699,449
JBrowse link
G Zkscan5 zinc finger with KRAB and SCAN domains 5 decreases expression EXP Thalidomide results in decreased expression of ZKSCAN5 mRNA CTD PMID:26217789 NCBI chr 5:145,141,349...145,158,562
Ensembl chr 5:145,141,372...145,158,560
JBrowse link
G Zmat5 zinc finger, matrin type 5 decreases expression EXP Thalidomide results in decreased expression of ZMAT5 mRNA CTD PMID:26217789 NCBI chr11:4,654,671...4,687,669
Ensembl chr11:4,654,678...4,687,669
JBrowse link
G Znrd2 zinc ribbon domain containing 2 decreases expression EXP Thalidomide results in decreased expression of ZNRD2 mRNA CTD PMID:26217789 NCBI chr19:5,780,334...5,781,760
Ensembl chr19:5,780,331...5,781,760
Ensembl chr19:5,780,331...5,781,760
JBrowse link
G Zscan12 zinc finger and SCAN domain containing 12 decreases expression EXP Thalidomide results in decreased expression of ZSCAN12 mRNA CTD PMID:26217789 NCBI chr13:21,546,982...21,556,472
Ensembl chr13:21,546,990...21,556,459
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      biological role 22178
        antimicrobial agent 19567
          antibacterial agent 16156
            antibacterial drug 4613
              antimycobacterial drug 1095
                leprostatic drug 908
                  clofazimine 10
                  dapsone + 39
                  ethionamide + 18
                  ethionamide S-oxide 0
                  rifampicin + 416
                  rifapentine 4
                  sulfamethoxydiazine 0
                  thalidomide + 522
Path 2
Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      application 21760
        pharmaceutical 21174
          drug 21174
            antiinfective agent 16301
              antimicrobial drug 9894
                antibacterial drug 4613
                  antimycobacterial drug 1095
                    leprostatic drug 908
                      clofazimine 10
                      dapsone + 39
                      ethionamide + 18
                      ethionamide S-oxide 0
                      rifampicin + 416
                      rifapentine 4
                      sulfamethoxydiazine 0
                      thalidomide + 522
paths to the root