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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:dicarboxylic acid monoamide
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Accession:CHEBI:35735 term browser browse the term
Synonyms:related_synonym: dicarboxylic acid monoamides
 alt_id: CHEBI:13210;   CHEBI:23691;   CHEBI:6976
 xref: KEGG:C04131
 cyclic_relationship: is_conjugate_acid_of CHEBI:77450



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asparagine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egf epidermal growth factor multiple interactions EXP [bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine; Cycloheximide inhibits the reaction [[bafilomycin A1 co-treated with EGF protein] results in decreased abundance of Asparagine] CTD PMID:22689575 NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064
JBrowse link
candoxatrilat term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mme membrane metallo-endopeptidase decreases activity ISO candoxatrilat results in decreased activity of MME protein CTD PMID:18084312 NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792
JBrowse link
G Mmel1 membrane metallo-endopeptidase-like 1 decreases activity ISO candoxatrilat results in decreased activity of MMEL1 protein CTD PMID:18084312 NCBI chr 5:165,431,278...165,461,716
Ensembl chr 5:165,431,343...165,461,716
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP candoxatrilat inhibits the reaction [Carbon Tetrachloride results in decreased secretion of NPPA protein] CTD PMID:16449355 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
CGS-21680 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy5 adenylate cyclase 5 increases response to substance
multiple interactions
ISO ADCY5 protein results in increased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine
ADCY5 protein results in increased susceptibility to [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with Quinpirole]
CTD PMID:12223546 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974
JBrowse link
G Adora2a adenosine A2a receptor increases response to substance
multiple interactions
ISO
EXP
ADORA2A protein results in increased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A protein]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [Oxygen deficiency results in increased expression of ADORA2A mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [Oxygen deficiency results in increased expression of ADORA2A protein]; 8-(3-chlorostyryl)caffeine inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A mRNA]]; 8-(3-chlorostyryl)caffeine inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA2A protein]]; PRKCZ protein affects the reaction [[2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein] which results in decreased expression of VEGFA mRNA]
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of ADORA2A mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of ADORA2A protein]
CTD PMID:11172060 PMID:12590138 PMID:15452191 PMID:19749167 PMID:19966059 More... NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of BDNF mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of BDNF protein] CTD PMID:35917217 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of BECN1 protein] CTD PMID:30555576 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 increases expression
multiple interactions
ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of BMAL1 mRNA
[2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in increased expression of BMAL1 mRNA
CTD PMID:22923002 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]] CTD PMID:30555576 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Clock clock circadian regulator increases expression ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of CLOCK mRNA CTD PMID:22923002 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400
JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression
multiple interactions
ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of COL3A1 protein
CTNNB1 protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of COL3A1 protein]
CTD PMID:27595240 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of CREB1 mRNA] CTD PMID:35917217 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Ctnnb1 catenin beta 1 affects localization
multiple interactions
ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine affects the localization of CTNNB1 protein modified form
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of and affects the phosphorylation of CTNNB1 protein; CTNNB1 protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of COL3A1 protein]
CTD PMID:27595240 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide results in decreased expression of CYP27A1 protein] CTD PMID:19035488 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
JBrowse link
G Ephx2 epoxide hydrolase 2 multiple interactions
increases response to substance
decreases response to substance
ISO 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [EPHX2 gene results in decreased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine]; 14,15-eicosa-5-enoic acid inhibits the reaction [EPHX2 gene mutant form results in increased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine]; 4-(4-(3-adamantan-1-ylureido)cyclohexyloxy)benzoic acid inhibits the reaction [EPHX2 gene results in decreased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine]; T 0070907 inhibits the reaction [EPHX2 gene mutant form results in increased susceptibility to 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine] CTD PMID:23152114 NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of FOS mRNA] CTD PMID:15452191 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of HMGCR mRNA] CTD PMID:30825513 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of HMGCS1 mRNA] CTD PMID:30825513 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Il10 interleukin 10 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [TNF protein results in increased expression of IL10 mRNA] CTD PMID:22923002 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12a interleukin 12A multiple interactions ISO [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in decreased expression of IL12A mRNA CTD PMID:22923002 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734
JBrowse link
G Lep leptin multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of LEP mRNA] CTD PMID:26367767 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased cleavage of MAP1LC3B protein] CTD PMID:30555576 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mmp14 matrix metallopeptidase 14 decreases activity ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased activity of MMP14 protein CTD PMID:16783407 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases activity ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased activity of MMP2 protein CTD PMID:16783407 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases activity
decreases expression
ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased activity of MMP9 protein
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of MMP9 mRNA
CTD PMID:16783407 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nppa natriuretic peptide A multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]; Caffeine analog inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]] CTD PMID:15452191 PMID:19966059 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of NR1D1 mRNA CTD PMID:22923002 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions
increases expression
EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of NTRK2 mRNA]
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of NTRK2 mRNA
CTD PMID:35917217 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Per2 period circadian regulator 2 decreases expression ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of PER2 mRNA CTD PMID:22923002 NCBI chr 9:92,007,289...92,049,551
Ensembl chr 9:92,007,296...92,049,459
JBrowse link
G Prkce protein kinase C, epsilon multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine affects the localization of and results in increased activity of PRKCE protein CTD PMID:12590138 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719
JBrowse link
G Prkcz protein kinase C, zeta multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine affects the localization of and results in increased activity of PRKCZ protein; PRKCZ protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of VEGFA mRNA]; PRKCZ protein affects the reaction [[2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein] which results in decreased expression of VEGFA mRNA] CTD PMID:12590138 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
JBrowse link
G Ren renin multiple interactions
increases expression
EXP Atenolol inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased expression of REN protein] CTD PMID:9300315 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of RGS2 mRNA] CTD PMID:15452191 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in decreased expression of SIRT1 mRNA] CTD PMID:30825513 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt3 sirtuin 3 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in decreased expression of SIRT3 protein]] CTD PMID:30555576 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808
JBrowse link
G Slc9a1 solute carrier family 9 member A1 multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Phenylephrine results in increased expression of SLC9A1 protein] CTD PMID:15452191 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624
JBrowse link
G Smad3 SMAD family member 3 multiple interactions EXP 8-(4-methoxyphenyl)-4-oxo-4,6,7,8-tetrahydroimidazo(2,1-c)(1,2,4)triazine-3-carbohydrazide inhibits the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of SMAD3 protein] CTD PMID:22063920 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions EXP 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [Oxygen deficiency results in increased expression of SOCS3 mRNA]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [Oxygen deficiency results in increased expression of SOCS3 protein] CTD PMID:27289578 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of SREBF2 mRNA] CTD PMID:30825513 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of TNF protein]; 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine promotes the reaction [TNF protein results in increased expression of IL10 mRNA]; [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in decreased expression of IL12A mRNA; [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine co-treated with TNF protein] results in increased expression of BMAL1 mRNA CTD PMID:21538184 PMID:22923002 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TP53 protein]] CTD PMID:30555576 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Vegfa vascular endothelial growth factor A increases secretion
decreases expression
multiple interactions
ISO
EXP
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in increased secretion of VEGFA protein
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of VEGFA mRNA
2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; PRKCZ protein affects the reaction [2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine results in decreased expression of VEGFA mRNA]; PRKCZ protein affects the reaction [[2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine binds to and results in increased activity of ADORA2A protein] which results in decreased expression of VEGFA mRNA]
CTD PMID:12590138 PMID:20067761 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
iooxitalamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ren renin multiple interactions
increases expression
EXP Acetylcysteine inhibits the reaction [ioxitalamic acid results in increased expression of REN protein]; Propranolol inhibits the reaction [ioxitalamic acid results in increased expression of REN protein] CTD PMID:19945959 NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
JBrowse link
melagatran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin multiple interactions ISO melagatran binds to and results in decreased activity of F2 protein CTD PMID:16084352 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link
oxamic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ldha lactate dehydrogenase A decreases activity
multiple interactions
ISO Oxamic Acid results in decreased activity of LDHA protein
[Oxamic Acid results in decreased activity of LDHA protein] which results in increased susceptibility to Paclitaxel
CTD PMID:21332213 NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472
JBrowse link
saquinavir term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO Saquinavir inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Saquinavir results in decreased activity of ABCB11 protein
CTD PMID:20829430 PMID:23956101 PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases export
affects uptake
affects export
ISO ABCB1 protein results in increased export of Saquinavir
ABCB1A protein affects the uptake of Saquinavir
ABCB1 protein affects the export of Saquinavir
CTD PMID:10562306 PMID:15832500 PMID:18535159 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects uptake ISO ABCB1B protein affects the uptake of Saquinavir CTD PMID:10562306 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 increases export ISO ABCC1 protein results in increased export of Saquinavir CTD PMID:18535159 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 affects export
multiple interactions
increases export
ISO ABCC2 protein affects the export of Saquinavir
montelukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir]; verlukast inhibits the reaction [ABCC2 protein results in increased export of Saquinavir]
CTD PMID:15832500 PMID:18535159 PMID:19952419 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
multiple interactions
ISO Saquinavir results in decreased expression of ADIPOQ mRNA; Saquinavir results in decreased expression of ADIPOQ protein
[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ADIPOQ mRNA; rosiglitazone inhibits the reaction [Saquinavir results in decreased secretion of ADIPOQ protein]
CTD PMID:15865214 PMID:16931933 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of AEBP1 mRNA CTD PMID:16931933 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
JBrowse link
G Alb albumin affects binding ISO Saquinavir binds to ALB protein CTD PMID:15814459 PMID:16336266 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ALOX5AP mRNA CTD PMID:16931933 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Arpp21 cAMP regulated phosphoprotein 21 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ARPP21 mRNA CTD PMID:16931933 NCBI chr 8:112,034,636...112,199,273
Ensembl chr 8:112,034,642...112,194,297
JBrowse link
G Asic2 acid sensing ion channel subunit 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ASIC2 mRNA CTD PMID:16931933 NCBI chr10:65,870,592...66,940,577
Ensembl chr10:65,870,594...66,940,424
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Saquinavir results in increased expression of ATF6 protein CTD PMID:19147209 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G C1r complement C1r multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C1R mRNA CTD PMID:16931933 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
JBrowse link
G C3ar1 complement C3a receptor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of C3AR1 mRNA CTD PMID:16931933 NCBI chr 4:156,074,747...156,084,680
Ensembl chr 4:156,075,389...156,084,701
JBrowse link
G Casp9 caspase 9 increases cleavage ISO Saquinavir results in increased cleavage of CASP9 protein CTD PMID:19147209 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CD36 mRNA CTD PMID:16931933 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cfd complement factor D multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CFD mRNA CTD PMID:16931933 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Cidec cell death-inducing DFFA-like effector c multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CIDEC mRNA CTD PMID:16931933 NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of CLCN3 mRNA CTD PMID:16931933 NCBI chr16:29,127,152...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO Saquinavir inhibits the reaction [Morphine results in increased expression of CYBB protein] CTD PMID:14871405 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Saquinavir results in increased expression of CYP1A1 mRNA CTD PMID:9860486 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity
increases metabolic processing
ISO Glutathione inhibits the reaction [Saquinavir results in decreased activity of CYP3A4 protein]
CYP3A4 protein results in increased metabolism of Saquinavir
CTD PMID:11824416 PMID:15523003 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dcn decorin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DCN mRNA CTD PMID:16931933 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270
JBrowse link
G Dusp3 dual specificity phosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of DUSP3 mRNA CTD PMID:16931933 NCBI chr10:86,920,014...86,933,739
Ensembl chr10:86,920,014...86,933,962
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ELOVL3 mRNA CTD PMID:16931933 NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of ESR2 mRNA CTD PMID:16931933 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Etv6 ETS variant transcription factor 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of ETV6 mRNA CTD PMID:16931933 NCBI chr 4:166,849,031...167,085,211
Ensembl chr 4:166,847,686...167,084,992
JBrowse link
G Fads2 fatty acid desaturase 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of FADS2 mRNA CTD PMID:16931933 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
JBrowse link
G Faim Fas apoptotic inhibitory molecule multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of FAIM mRNA CTD PMID:16931933 NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562
JBrowse link
G G0s2 G0/G1switch 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of G0S2 mRNA CTD PMID:16931933 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
JBrowse link
G Ganc glucosidase, alpha; neutral C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of GANC mRNA CTD PMID:16931933 NCBI chr 3:107,353,369...107,406,104
Ensembl chr 3:107,353,369...107,405,241
JBrowse link
G Gucy1b1 guanylate cyclase 1 soluble subunit beta 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of GUCY1B1 mRNA CTD PMID:16931933 NCBI chr 2:167,348,824...167,398,983
Ensembl chr 2:167,348,825...167,398,916
JBrowse link
G Hadh hydroxyacyl-CoA dehydrogenase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of HADH mRNA CTD PMID:16931933 NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of HCN1 mRNA CTD PMID:16931933 NCBI chr 2:49,495,771...49,899,983
Ensembl chr 2:49,495,771...49,899,774
JBrowse link
G Hist1h4b histone cluster 1 H4 family member B multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of H4C9 mRNA CTD PMID:16931933 NCBI chr17:42,480,467...42,484,912
Ensembl chr17:42,480,313...42,485,370
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Saquinavir results in increased expression of HSPA5 protein CTD PMID:19147209 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Ikzf4 IKAROS family zinc finger 4 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of IKZF4 mRNA CTD PMID:16931933 NCBI chr 7:1,063,283...1,102,940
Ensembl chr 7:1,056,890...1,084,341
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO Saquinavir results in increased expression of IL6 mRNA; Saquinavir results in increased expression of IL6 protein
rosiglitazone inhibits the reaction [Saquinavir results in increased expression of IL6 mRNA]
Saquinavir inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]
CTD PMID:15388451 PMID:15865214 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Saquinavir inhibits the reaction [INS protein results in increased import of Glucose] CTD PMID:11786383 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Klhl28 kelch-like family member 28 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of KLHL28 mRNA CTD PMID:16931933 NCBI chr 6:82,987,360...83,018,971
Ensembl chr 6:82,990,945...83,016,164
JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of LAMC2 mRNA CTD PMID:16931933 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
JBrowse link
G Lef1 lymphoid enhancer binding factor 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEF1 mRNA CTD PMID:16931933 NCBI chr 2:219,666,549...219,779,815
Ensembl chr 2:219,666,592...219,779,794
JBrowse link
G Lep leptin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of LEP mRNA CTD PMID:16931933 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lpl lipoprotein lipase decreases activity
decreases expression
ISO Saquinavir results in decreased activity of LPL protein
Saquinavir results in decreased expression of LPL mRNA
CTD PMID:11741158 PMID:11786383 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Me1 malic enzyme 1 decreases expression ISO Saquinavir results in decreased expression of ME1 mRNA CTD PMID:11741158 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mgat4c MGAT4 family, member C multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA CTD PMID:16931933 NCBI chr 7:36,709,564...37,485,810
Ensembl chr 7:37,260,321...37,474,571
JBrowse link
G Mrap melanocortin 2 receptor accessory protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of MRAP mRNA CTD PMID:16931933 NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024
JBrowse link
G Myod1 myogenic differentiation 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MYOD1 mRNA CTD PMID:16931933 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554
JBrowse link
G Nap1l5 nucleosome assembly protein 1-like 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NAP1L5 mRNA CTD PMID:16931933 NCBI chr 4:88,022,670...88,024,988
Ensembl chr 4:88,022,569...88,024,654
JBrowse link
G Noct nocturnin multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of NOCT mRNA CTD PMID:16931933 NCBI chr 2:135,271,189...135,291,407
Ensembl chr 2:135,271,189...135,291,400
JBrowse link
G Notch4 notch receptor 4 multiple interactions
decreases expression
EXP [Saquinavir co-treated with Nicotine co-treated with Ritonavir] results in decreased expression of NOTCH4 protein; [Saquinavir co-treated with Nicotine] results in decreased expression of NOTCH4 protein; Vitamin E inhibits the reaction [[Nicotine co-treated with Ritonavir co-treated with Saquinavir] results in decreased expression of NOTCH4 protein]; Vitamin E inhibits the reaction [[Nicotine co-treated with Saquinavir] results in decreased expression of NOTCH4 protein]
Saquinavir results in decreased expression of NOTCH4 protein
CTD PMID:20722969 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO NR1I2 gene promotes the reaction [Rifampin results in increased metabolism of Saquinavir] CTD PMID:18799805 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nup210 nucleoporin 210 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of NUP210 mRNA CTD PMID:16931933 NCBI chr 4:123,511,558...123,609,874
Ensembl chr 4:123,511,559...123,609,874
JBrowse link
G Oaz3 ornithine decarboxylase antizyme 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of OAZ3 mRNA CTD PMID:16931933 NCBI chr 2:182,073,212...182,076,147
Ensembl chr 2:182,073,215...182,082,399
JBrowse link
G Pcdh15 protocadherin related 15 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PCDH15 mRNA CTD PMID:16931933 NCBI chr20:13,997,094...15,496,446
Ensembl chr20:13,963,565...15,494,719
JBrowse link
G Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PFKFB3 mRNA CTD PMID:16931933 NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125
JBrowse link
G Phf6 PHD finger protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of PHF6 mRNA CTD PMID:16931933 NCBI chr  X:132,656,658...132,699,720
Ensembl chr  X:132,656,672...132,699,127
JBrowse link
G Pidd1 p53-induced death domain protein 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIDD1 mRNA CTD PMID:16931933 NCBI chr 1:196,536,815...196,542,808
Ensembl chr 1:196,536,834...196,542,699
JBrowse link
G Piwil2 piwi-like RNA-mediated gene silencing 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PIWIL2 mRNA CTD PMID:16931933 NCBI chr15:45,431,402...45,498,034
Ensembl chr15:45,431,703...45,497,702
JBrowse link
G Pon1 paraoxonase 1 decreases activity EXP Saquinavir results in decreased activity of PON1 protein CTD PMID:27378623 NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
JBrowse link
G Porcn porcupine O-acyltransferase multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PPN mRNA CTD PMID:16931933 NCBI chr  X:14,285,864...14,298,481
Ensembl chr  X:14,285,871...14,298,481
JBrowse link
G Pou5f1 POU class 5 homeobox 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of POU5F1 mRNA CTD PMID:16931933 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891
JBrowse link
G Prdm1 PR/SET domain 1 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of PRDM1 mRNA CTD PMID:16931933 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488
JBrowse link
G Reep6 receptor accessory protein 6 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of REEP6 mRNA CTD PMID:16931933 NCBI chr 7:9,373,927...9,380,845
Ensembl chr 7:9,373,927...9,380,597
JBrowse link
G Rnf151 ring finger protein 151 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of RNF151 mRNA CTD PMID:16931933 NCBI chr10:13,742,682...13,747,192
Ensembl chr10:13,742,682...13,745,000
JBrowse link
G Rpain RPA interacting protein multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of RPAIN mRNA CTD PMID:16931933 NCBI chr10:55,692,410...55,699,910
Ensembl chr10:55,692,417...55,699,933
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 affects expression ISO Saquinavir affects the expression of HLA-F mRNA CTD PMID:25811541 NCBI chr20:3,403,418...3,479,476 JBrowse link
G RT1-DOa RT1 class II, locus DOa affects expression ISO Saquinavir affects the expression of HLA-DOA mRNA CTD PMID:25811541 NCBI chr20:4,753,587...4,756,590
Ensembl chr20:4,753,598...4,756,577
JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in decreased expression of S100A8 mRNA CTD PMID:16931933 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 affects uptake ISO SLCO1A2 protein affects the uptake of Saquinavir CTD PMID:15832500 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO Saquinavir inhibits the reaction [Morphine results in increased expression of SOD2 protein] CTD PMID:14871405 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Spink5 serine peptidase inhibitor, Kazal type 5 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of SPINK5 mRNA CTD PMID:16931933 NCBI chr18:36,264,452...36,333,143
Ensembl chr18:36,264,452...36,332,185
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b affects response to substance ISO SV2B gene SNP affects the susceptibility to Saquinavir CTD PMID:25622337 NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TIMP2 mRNA CTD PMID:16931933 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions
decreases expression
EXP [Saquinavir co-treated with Nicotine co-treated with Ritonavir] results in decreased expression of TJP1 protein; [Saquinavir co-treated with Nicotine] results in decreased expression of TJP1 protein; Vitamin E inhibits the reaction [[Nicotine co-treated with Ritonavir co-treated with Saquinavir] results in decreased expression of TJP1 protein]; Vitamin E inhibits the reaction [[Nicotine co-treated with Saquinavir] results in decreased expression of TJP1 protein]
Saquinavir results in decreased expression of TJP1 protein
CTD PMID:20722969 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
ISO Saquinavir inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Saquinavir results in increased expression of TNF mRNA; Saquinavir results in increased expression of TNF protein
rosiglitazone inhibits the reaction [Saquinavir results in increased expression of TNF mRNA]
CTD PMID:15388451 PMID:15865214 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Trim42 tripartite motif-containing 42 multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of TRIM42 mRNA CTD PMID:16931933 NCBI chr 8:97,902,349...97,923,268
Ensembl chr 8:97,902,353...97,923,268
JBrowse link
G Wnt10a Wnt family member 10A multiple interactions ISO [Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of WNT10A mRNA CTD PMID:16931933 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400
JBrowse link
tamibarotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acan aggrecan affects expression ISO tamibarotene affects the expression of ACAN mRNA CTD PMID:15498508 NCBI chr 1:132,981,582...133,044,416
Ensembl chr 1:132,981,582...133,043,627
JBrowse link
G Acvrl1 activin A receptor like type 1 decreases expression ISO tamibarotene results in decreased expression of ACVRL1 mRNA CTD PMID:15498508 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591
JBrowse link
G Ada adenosine deaminase increases expression ISO tamibarotene results in increased expression of ADA mRNA CTD PMID:15498508 NCBI chr 3:152,398,745...152,422,854
Ensembl chr 3:152,398,747...152,447,088
JBrowse link
G Adgre1 adhesion G protein-coupled receptor E1 increases expression ISO tamibarotene results in increased expression of ADGRE1 mRNA CTD PMID:15498508 NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000
JBrowse link
G Adnp2 ADNP homeobox 2 affects expression ISO tamibarotene affects the expression of ADNP2 mRNA CTD PMID:15498508 NCBI chr18:73,571,870...73,597,088
Ensembl chr18:73,571,936...73,628,484
JBrowse link
G Adora3 adenosine A3 receptor affects expression ISO tamibarotene affects the expression of ADORA3 mRNA CTD PMID:15498508 NCBI chr 2:193,352,759...193,392,946
Ensembl chr 2:193,388,713...193,392,357
JBrowse link
G Agps alkylglycerone phosphate synthase affects expression ISO tamibarotene affects the expression of AGPS mRNA CTD PMID:15498508 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830
JBrowse link
G Agt angiotensinogen multiple interactions ISO tamibarotene inhibits the reaction [AGT protein results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [AGT protein results in increased secretion of IL6 protein] CTD PMID:16484594 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
JBrowse link
G Ahnak AHNAK nucleoprotein decreases expression ISO tamibarotene results in decreased expression of AHNAK mRNA CTD PMID:15498508 NCBI chr 1:205,882,225...205,970,934
Ensembl chr 1:205,882,273...205,970,926
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO tamibarotene results in increased expression of AIF1 mRNA CTD PMID:15498508 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Ak4 adenylate kinase 4 decreases expression ISO tamibarotene results in decreased expression of AK4 mRNA CTD PMID:15498508 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618
JBrowse link
G Akap9 A-kinase anchoring protein 9 decreases expression ISO tamibarotene results in decreased expression of AKAP9 mRNA CTD PMID:15498508 NCBI chr 4:30,056,738...30,192,716
Ensembl chr 4:30,056,738...30,192,606
JBrowse link
G Alas1 5'-aminolevulinate synthase 1 increases expression ISO tamibarotene results in increased expression of ALAS1 mRNA CTD PMID:15498508 NCBI chr 8:106,876,514...106,889,917
Ensembl chr 8:106,876,514...106,889,917
JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 affects expression ISO tamibarotene affects the expression of ALDH1B1 mRNA CTD PMID:15498508 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Alms1 ALMS1, centrosome and basal body associated protein decreases expression ISO tamibarotene results in decreased expression of ALMS1 mRNA CTD PMID:15498508 NCBI chr 4:118,125,581...118,226,005
Ensembl chr 4:118,125,607...118,226,005
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression ISO tamibarotene results in increased expression of ALOX5AP mRNA CTD PMID:15498508 NCBI chr12:5,748,941...5,772,986
Ensembl chr12:5,748,944...5,772,986
JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 decreases expression ISO tamibarotene results in decreased expression of AMD1 mRNA CTD PMID:15498508 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476
JBrowse link
G Ankrd17 ankyrin repeat domain 17 decreases expression ISO tamibarotene results in decreased expression of ANKRD17 mRNA CTD PMID:15498508 NCBI chr14:17,723,239...17,861,841
Ensembl chr14:17,721,932...17,862,617
JBrowse link
G Anxa2 annexin A2 decreases expression ISO tamibarotene results in decreased expression of ANXA2 mRNA CTD PMID:15498508 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Ap1s2 adaptor related protein complex 1 subunit sigma 2 increases expression ISO tamibarotene results in increased expression of AP1S2 mRNA CTD PMID:15498508 NCBI chr  X:30,572,746...30,598,961
Ensembl chr  X:30,572,751...30,597,262
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 affects expression ISO tamibarotene affects the expression of APBB3 mRNA CTD PMID:15498508 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression ISO tamibarotene results in decreased expression of APC mRNA CTD PMID:15498508 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Aqp7 aquaporin 7 affects expression ISO tamibarotene affects the expression of AQP7 mRNA CTD PMID:15498508 NCBI chr 5:56,171,649...56,186,642
Ensembl chr 5:56,172,519...56,186,642
JBrowse link
G Arf6 ADP-ribosylation factor 6 affects expression ISO tamibarotene affects the expression of ARF6 mRNA CTD PMID:15498508 NCBI chr 6:87,853,742...87,854,890
Ensembl chr 6:87,840,142...87,874,114
JBrowse link
G Arhgap4 Rho GTPase activating protein 4 increases expression ISO tamibarotene results in increased expression of ARHGAP4 mRNA CTD PMID:15498508 NCBI chr  X:151,636,071...151,651,528
Ensembl chr  X:151,632,454...151,651,128
JBrowse link
G Arhgap45 Rho GTPase activating protein 45 increases expression ISO tamibarotene results in increased expression of ARHGAP45 mRNA CTD PMID:15498508 NCBI chr 7:9,674,873...9,690,286
Ensembl chr 7:9,674,897...9,690,268
JBrowse link
G Arhgap8 Rho GTPase activating protein 8 increases expression ISO tamibarotene results in increased expression of ARHGAP8 mRNA CTD PMID:17229644 NCBI chr 7:115,842,223...115,902,094
Ensembl chr 7:115,850,654...115,902,093
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C decreases expression ISO tamibarotene results in decreased expression of ARL4C mRNA CTD PMID:15498508 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513
JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 increases expression ISO tamibarotene results in increased expression of ASB2 mRNA CTD PMID:17229644 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854
JBrowse link
G Atp13a3 ATPase 13A3 affects expression ISO tamibarotene affects the expression of ATP13A3 mRNA CTD PMID:15498508 NCBI chr11:70,364,998...70,442,005
Ensembl chr11:70,365,322...70,441,235
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 affects expression ISO tamibarotene affects the expression of ATP1A3 mRNA CTD PMID:15498508 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 affects expression ISO tamibarotene affects the expression of ATP2B1 mRNA CTD PMID:15498508 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Atp6v0a1 ATPase H+ transporting V0 subunit a1 increases expression ISO tamibarotene results in increased expression of ATP6V0A1 mRNA CTD PMID:15498508 NCBI chr10:85,935,802...85,989,901
Ensembl chr10:85,935,854...85,989,895
JBrowse link
G Atp6v0a2 ATPase H+ transporting V0 subunit a2 decreases expression ISO tamibarotene results in decreased expression of ATP6V0A2 mRNA CTD PMID:15498508 NCBI chr12:31,947,220...31,979,875
Ensembl chr12:31,822,733...32,007,069
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A affects expression ISO tamibarotene affects the expression of ATP6V1A mRNA CTD PMID:15498508 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 affects expression ISO tamibarotene affects the expression of ATPAF2 mRNA CTD PMID:15498508 NCBI chr10:45,205,658...45,221,891
Ensembl chr10:45,197,441...45,221,026
JBrowse link
G Atrx ATRX, chromatin remodeler decreases expression ISO tamibarotene results in decreased expression of ATRX mRNA CTD PMID:15498508 NCBI chr  X:70,850,981...70,997,330
Ensembl chr  X:70,850,981...70,997,330
JBrowse link
G Atxn7l3b ataxin 7-like 3B affects expression ISO tamibarotene affects the expression of ATXN7L3B mRNA CTD PMID:15498508 NCBI chr 7:48,322,451...48,325,975
Ensembl chr 7:48,321,755...48,328,878
JBrowse link
G Axin1 axin 1 increases expression ISO tamibarotene results in increased expression of AXIN1 mRNA CTD PMID:15498508 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615
JBrowse link
G Azin1 antizyme inhibitor 1 affects expression ISO tamibarotene affects the expression of AZIN1 mRNA CTD PMID:15498508 NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO tamibarotene results in increased expression of BAK1 mRNA CTD PMID:15498508 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bcat1 branched chain amino acid transaminase 1 affects expression ISO tamibarotene affects the expression of BCAT1 mRNA CTD PMID:15498508 NCBI chr 4:177,964,834...178,046,573
Ensembl chr 4:177,964,834...178,046,597
JBrowse link
G Bcl11a BCL11 transcription factor A decreases expression ISO tamibarotene results in decreased expression of BCL11A mRNA CTD PMID:15498508 NCBI chr14:98,029,018...98,124,181
Ensembl chr14:98,030,461...98,124,180
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
affects expression
ISO Triiodothyronine promotes the reaction [tamibarotene results in decreased expression of BCL2 mRNA]
tamibarotene affects the expression of BCL2 mRNA
CTD PMID:11201846 PMID:15498508 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression
multiple interactions
ISO tamibarotene results in increased expression of BCL2A1 mRNA; tamibarotene results in increased expression of BCL2A1A mRNA
Triiodothyronine promotes the reaction [tamibarotene results in increased expression of BCL2A1A mRNA]
CTD PMID:11201846 PMID:15498508 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
JBrowse link
G Bcl7a BAF chromatin remodeling complex subunit BCL7A decreases expression ISO tamibarotene results in decreased expression of BCL7A mRNA CTD PMID:15498508 NCBI chr12:33,211,978...33,243,903
Ensembl chr12:33,223,931...33,243,886
JBrowse link
G Bclaf1 BCL2-associated transcription factor 1 decreases expression ISO tamibarotene results in decreased expression of BCLAF1 mRNA CTD PMID:15498508 NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
ISO
EXP
[tamibarotene co-treated with BDNF] results in increased expression of NTRK2
BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK1 protein]; BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK3 protein]; BDNF affects the reaction [tamibarotene results in increased phosphorylation of NTRK2 protein]
tamibarotene results in increased expression of BDNF mRNA
CTD PMID:19182380 PMID:19457078 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 affects expression ISO tamibarotene affects the expression of BHLHE40 mRNA CTD PMID:15498508 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
JBrowse link
G Blmh bleomycin hydrolase decreases expression ISO tamibarotene results in decreased expression of BLMH mRNA CTD PMID:15498508 NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212
JBrowse link
G Bltp1 bridge-like lipid transfer protein family member 1 affects expression ISO tamibarotene affects the expression of BLTP1 mRNA CTD PMID:15498508 NCBI chr 2:119,708,114...119,924,697
Ensembl chr 2:119,708,209...119,924,695
JBrowse link
G Bpi bactericidal/permeability-increasing protein increases expression ISO tamibarotene results in increased expression of BPI mRNA CTD PMID:15498508 NCBI chr 3:146,909,626...146,936,487
Ensembl chr 3:146,909,629...146,936,221
JBrowse link
G Bptf bromodomain PHD finger transcription factor affects expression ISO tamibarotene affects the expression of BPTF mRNA CTD PMID:15498508 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO tamibarotene results in decreased expression of BRCA1 mRNA CTD PMID:15498508 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated affects expression
decreases expression
ISO tamibarotene affects the expression of BRCA2 mRNA
tamibarotene results in decreased expression of BRCA2 mRNA
CTD PMID:15498508 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Brd3 bromodomain containing 3 affects expression ISO tamibarotene affects the expression of BRD3 mRNA CTD PMID:15498508 NCBI chr 3:10,773,163...10,829,675
Ensembl chr 3:10,775,272...10,829,577
JBrowse link
G Bst2 bone marrow stromal cell antigen 2 affects expression ISO tamibarotene affects the expression of BST2 mRNA CTD PMID:15498508 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979
JBrowse link
G Btf3 basic transcription factor 3 affects expression ISO tamibarotene affects the expression of BTF3 mRNA CTD PMID:15498508 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO tamibarotene results in increased expression of BTG2 mRNA CTD PMID:15498508 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Cadm1 cell adhesion molecule 1 increases expression ISO tamibarotene results in increased expression of CADM1 mRNA CTD PMID:15498508 NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
JBrowse link
G Camk1 calcium/calmodulin-dependent protein kinase I increases expression ISO tamibarotene results in increased expression of CAMK1 mRNA CTD PMID:15498508 NCBI chr 4:146,481,196...146,492,039
Ensembl chr 4:146,481,196...146,492,081
JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression ISO tamibarotene results in increased expression of CAMTA2 mRNA CTD PMID:15498508 NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558
JBrowse link
G Capg capping actin protein, gelsolin like increases expression ISO tamibarotene results in increased expression of CAPG mRNA CTD PMID:15498508 NCBI chr 4:104,594,743...104,611,856
Ensembl chr 4:104,594,753...104,611,856
JBrowse link
G Caprin1 cell cycle associated protein 1 decreases expression ISO tamibarotene results in decreased expression of CAPRIN1 mRNA CTD PMID:15498508 NCBI chr 3:90,152,305...90,230,447
Ensembl chr 3:90,153,620...90,230,502
JBrowse link
G Casp9 caspase 9 increases expression ISO tamibarotene results in increased expression of CASP9 mRNA CTD PMID:15498508 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cbx3 chromobox 3 affects expression ISO tamibarotene affects the expression of CBX3 mRNA CTD PMID:15498508 NCBI chr 4:80,545,450...80,559,284
Ensembl chr 4:80,546,010...80,559,283
JBrowse link
G Ccdc22 coiled-coil domain containing 22 affects expression ISO tamibarotene affects the expression of CCDC22 mRNA CTD PMID:15498508 NCBI chr  X:14,898,296...14,910,244
Ensembl chr  X:14,898,296...14,910,244
JBrowse link
G Ccdc93 coiled-coil domain containing 93 decreases expression ISO tamibarotene results in decreased expression of CCDC93 mRNA CTD PMID:15498508 NCBI chr13:32,607,618...32,675,993
Ensembl chr13:32,607,587...32,676,023
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 increases expression ISO tamibarotene results in increased expression of CCL4 mRNA CTD PMID:15498508 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
decreases expression
ISO tamibarotene results in increased expression of CCL5 mRNA
tamibarotene results in decreased expression of CCL5 mRNA
CTD PMID:15498508 PMID:20861477 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl9 C-C motif chemokine ligand 9 decreases expression ISO tamibarotene results in decreased expression of CCL6 mRNA CTD PMID:20861477 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
JBrowse link
G Ccnd1 cyclin D1 increases expression ISO tamibarotene results in increased expression of CCND1 mRNA CTD PMID:15498508 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccnf cyclin F decreases expression ISO tamibarotene results in decreased expression of CCNF mRNA CTD PMID:15498508 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
JBrowse link
G Ccng1 cyclin G1 affects expression ISO tamibarotene affects the expression of CCNG1 mRNA CTD PMID:15498508 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccr1 C-C motif chemokine receptor 1 increases expression ISO tamibarotene results in increased expression of CCR1 mRNA CTD PMID:15498508 NCBI chr 8:123,556,286...123,561,841 JBrowse link
G Cd22 CD22 molecule affects expression ISO tamibarotene affects the expression of CD22 mRNA CTD PMID:15498508 NCBI chr 1:86,116,376...86,132,782
Ensembl chr 1:86,117,459...86,132,322
JBrowse link
G Cd300a Cd300a molecule increases expression ISO tamibarotene results in increased expression of CD300A mRNA CTD PMID:15498508 NCBI chr10:99,929,801...99,942,674
Ensembl chr10:99,929,801...99,942,674
JBrowse link
G Cd300c CD300c molecule increases expression ISO tamibarotene results in increased expression of CD300C mRNA CTD PMID:15498508 NCBI chr10:100,228,254...100,233,207
Ensembl chr10:100,228,430...100,232,879
JBrowse link
G Cd36 CD36 molecule multiple interactions ISO tamibarotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]
tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD36 mRNA]
CTD PMID:16484594 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
JBrowse link
G Cd38 CD38 molecule increases expression ISO tamibarotene results in increased expression of CD38 mRNA; tamibarotene results in increased expression of CD38 protein CTD PMID:15498508 PMID:21393419 NCBI chr14:67,172,062...67,212,328
Ensembl chr14:67,172,063...67,211,986
JBrowse link
G Cd3d CD3 delta subunit of T-cell receptor complex decreases expression ISO tamibarotene results in decreased expression of CD3D mRNA CTD PMID:20861477 NCBI chr 8:45,287,803...45,293,342
Ensembl chr 8:45,288,749...45,301,809
JBrowse link
G Cd3g CD3 gamma subunit of T-cell receptor complex decreases expression ISO tamibarotene results in decreased expression of CD3G mRNA CTD PMID:20861477 NCBI chr 8:45,280,797...45,287,271
Ensembl chr 8:45,281,204...45,287,147
JBrowse link
G Cd44 CD44 molecule decreases expression
affects expression
ISO tamibarotene results in decreased expression of CD44 mRNA
tamibarotene affects the expression of CD44 mRNA
CTD PMID:15498508 PMID:17229644 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd53 Cd53 molecule increases expression ISO tamibarotene results in increased expression of CD53 mRNA CTD PMID:15498508 NCBI chr 2:194,352,139...194,399,668
Ensembl chr 2:194,352,139...194,399,657
JBrowse link
G Cd68 Cd68 molecule decreases expression ISO tamibarotene results in decreased expression of CD68 mRNA CTD PMID:20861477 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697
JBrowse link
G Cd69 Cd69 molecule affects expression ISO tamibarotene affects the expression of CD69 mRNA CTD PMID:15498508 NCBI chr 4:162,725,446...162,733,364
Ensembl chr 4:162,725,446...162,733,542
JBrowse link
G Cd74 CD74 molecule increases expression ISO tamibarotene results in increased expression of CD74 mRNA CTD PMID:17229644 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003
JBrowse link
G Cd79a CD79a molecule increases expression ISO tamibarotene results in increased expression of CD79A mRNA CTD PMID:17229644 NCBI chr 1:80,493,581...80,497,936
Ensembl chr 1:80,493,581...80,497,935
JBrowse link
G Cdc25a cell division cycle 25A decreases expression ISO tamibarotene results in decreased expression of CDC25A mRNA CTD PMID:15498508 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO tamibarotene results in decreased expression of CDC6 mRNA CTD PMID:15498508 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdk10 cyclin-dependent kinase 10 affects expression ISO tamibarotene affects the expression of CDK10 mRNA CTD PMID:15498508 NCBI chr19:51,260,012...51,273,009
Ensembl chr19:51,261,356...51,269,078
JBrowse link
G Cdk8 cyclin-dependent kinase 8 affects expression ISO tamibarotene affects the expression of CDK8 mRNA CTD PMID:15498508 NCBI chr12:8,737,198...8,805,026
Ensembl chr12:8,737,262...8,804,177
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO tamibarotene results in increased expression of CDKN1A mRNA CTD PMID:17229644 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Ceacam6 CEA cell adhesion molecule 6 increases expression
multiple interactions
ISO tamibarotene results in increased expression of CEACAM6 mRNA
CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEACAM6 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEACAM6 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEACAM6 mRNA]
CTD PMID:27737899 NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression ISO tamibarotene results in increased expression of CEBPB mRNA CTD PMID:15498508 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO tamibarotene results in increased expression of CEBPD mRNA CTD PMID:15498508 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829
JBrowse link
G Cebpe CCAAT/enhancer binding protein epsilon increases expression
multiple interactions
ISO tamibarotene results in increased expression of CEBPE mRNA
CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEBPE mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEBPE mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEBPE mRNA]
CTD PMID:27737899 NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814
JBrowse link
G Cebpg CCAAT/enhancer binding protein gamma decreases expression ISO tamibarotene results in decreased expression of CEBPG mRNA CTD PMID:15498508 NCBI chr 1:87,683,060...87,692,772
Ensembl chr 1:87,684,019...87,694,569
JBrowse link
G Celf1 CUGBP, Elav-like family member 1 affects expression ISO tamibarotene affects the expression of CELF1 mRNA CTD PMID:15498508 NCBI chr 3:76,924,591...76,999,429
Ensembl chr 3:76,924,613...76,999,426
JBrowse link
G Cep135 centrosomal protein 135 decreases expression ISO tamibarotene results in decreased expression of CEP135 mRNA CTD PMID:15498508 NCBI chr14:31,530,538...31,595,812
Ensembl chr14:31,531,482...31,595,772
JBrowse link
G Chka choline kinase alpha decreases expression ISO tamibarotene results in decreased expression of CHKA mRNA CTD PMID:15498508 NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator increases expression ISO tamibarotene results in increased expression of CIITA mRNA CTD PMID:17229644 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Clcnka chloride voltage-gated channel Ka decreases expression ISO tamibarotene results in decreased expression of CLCNKA mRNA CTD PMID:15498508 NCBI chr 5:153,691,208...153,706,295
Ensembl chr 5:153,691,209...153,706,148
JBrowse link
G Cltb clathrin, light chain B increases expression ISO tamibarotene results in increased expression of CLTB mRNA CTD PMID:15498508 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169
JBrowse link
G Col11a2 collagen type XI alpha 2 chain affects expression ISO tamibarotene affects the expression of COL11A2 mRNA CTD PMID:15498508 NCBI chr20:4,786,932...4,816,598
Ensembl chr20:4,786,929...4,815,985
JBrowse link
G Coro1a coronin 1A increases expression ISO tamibarotene results in increased expression of CORO1A mRNA CTD PMID:15498508 NCBI chr 1:181,295,561...181,300,566
Ensembl chr 1:181,295,562...181,300,534
JBrowse link
G Creb1 cAMP responsive element binding protein 1 affects expression ISO tamibarotene affects the expression of CREB1 mRNA CTD PMID:15498508 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creb3 cAMP responsive element binding protein 3 increases expression ISO tamibarotene results in increased expression of CREB3 mRNA CTD PMID:15498508 NCBI chr 5:57,817,865...57,823,233
Ensembl chr 5:57,817,832...57,824,390
JBrowse link
G Creg1 cellular repressor of E1A-stimulated genes 1 increases expression ISO tamibarotene results in increased expression of CREG1 mRNA CTD PMID:15498508 NCBI chr13:78,019,814...78,032,310
Ensembl chr13:78,019,843...78,032,308
JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [tamibarotene co-treated with CSF3 protein] results in increased expression of CEACAM8 mRNA; CSF3 protein inhibits the reaction [tamibarotene results in decreased expression of ITGB2 mRNA]; CSF3 protein inhibits the reaction [tamibarotene results in increased expression of ITGAM mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEACAM6 mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of CEBPE mRNA]; CSF3 protein promotes the reaction [tamibarotene results in increased expression of RARB mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEACAM6 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in decreased expression of CEBPE mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in increased expression of ITGB2 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEACAM6 mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of CEBPE mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of RARB mRNA] CTD PMID:27737899 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 affects expression ISO tamibarotene affects the expression of CSRP1 mRNA CTD PMID:15498508 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Cst3 cystatin C increases expression ISO tamibarotene results in increased expression of CST3 mRNA CTD PMID:15498508 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822
JBrowse link
G Ctif cap binding complex dependent translation initiation factor decreases expression ISO tamibarotene results in decreased expression of CTIF mRNA CTD PMID:15498508 NCBI chr18:69,056,151...69,327,454
Ensembl chr18:69,059,519...69,327,385
JBrowse link
G Ctnnal1 catenin alpha-like 1 decreases expression ISO tamibarotene results in decreased expression of CTNNAL1 mRNA CTD PMID:15498508 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431
JBrowse link
G Ctsa cathepsin A increases expression ISO tamibarotene results in increased expression of CTSA mRNA CTD PMID:17229644 NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
JBrowse link
G Ctsd cathepsin D increases expression ISO tamibarotene results in increased expression of CTSD mRNA CTD PMID:15498508 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cul1 cullin 1 decreases expression ISO tamibarotene results in decreased expression of CUL1 mRNA CTD PMID:15498508 NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression ISO tamibarotene results in decreased expression of CXCL10 mRNA CTD PMID:20861477 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 decreases expression ISO tamibarotene results in decreased expression of CXCL9 mRNA CTD PMID:20861477 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions
decreases expression
ISO tamibarotene results in increased uptake of and affects the localization of CXCR4 protein
tamibarotene results in decreased expression of CXCR4 mRNA
CTD PMID:20141446 PMID:20861477 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 increases expression ISO tamibarotene results in increased expression of CXCR5 mRNA CTD PMID:15498508 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
JBrowse link
G Cyba cytochrome b-245 alpha chain increases expression ISO tamibarotene results in increased expression of CYBA mRNA CTD PMID:15498508 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression ISO tamibarotene results in increased expression of CYBB mRNA CTD PMID:15498508 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 multiple interactions ISO tamibarotene inhibits the reaction [Calcitriol results in increased expression of CYP24A1 mRNA] CTD PMID:16289102 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Daam1 dishevelled associated activator of morphogenesis 1 decreases expression ISO tamibarotene results in decreased expression of DAAM1 mRNA CTD PMID:15498508 NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114
JBrowse link
G Dagla diacylglycerol lipase, alpha affects expression ISO tamibarotene affects the expression of DAGLA mRNA CTD PMID:15498508 NCBI chr 1:206,890,635...206,947,332
Ensembl chr 1:206,890,638...206,947,232
JBrowse link
G Dapk2 death-associated protein kinase 2 increases expression ISO tamibarotene results in increased expression of DAPK2 mRNA CTD PMID:15498508 NCBI chr 8:66,706,536...66,825,567
Ensembl chr 8:66,706,609...66,825,567
JBrowse link
G Ddx18 DEAD-box helicase 18 affects expression ISO tamibarotene affects the expression of DDX18 mRNA CTD PMID:15498508 NCBI chr13:32,729,697...32,743,161
Ensembl chr13:32,729,700...32,743,161
JBrowse link
G Ddx21 DExD-box helicase 21 decreases expression ISO tamibarotene results in decreased expression of DDX21 mRNA CTD PMID:15498508 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Ddx51 DEAD-box helicase 51 affects expression ISO tamibarotene affects the expression of DDX51 mRNA CTD PMID:15498508 NCBI chr12:46,011,303...46,015,989
Ensembl chr12:46,011,070...46,016,200
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 increases expression ISO tamibarotene results in increased expression of DHRS3 mRNA CTD PMID:15498508 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dmbt1 deleted in malignant brain tumors 1 affects expression ISO tamibarotene affects the expression of DMBT1 mRNA CTD PMID:15498508 NCBI chr 1:185,617,469...185,696,476
Ensembl chr 1:185,617,294...185,696,478
JBrowse link
G Dok2 docking protein 2 increases expression ISO tamibarotene results in increased expression of DOK2 mRNA CTD PMID:15498508 NCBI chr15:45,826,984...45,841,409
Ensembl chr15:45,827,398...45,841,402
JBrowse link
G Dph1 diphthamide biosynthesis 1 increases expression ISO tamibarotene results in increased expression of DPH1 mRNA CTD PMID:15498508 NCBI chr10:60,028,081...60,039,764
Ensembl chr10:60,026,048...60,039,850
JBrowse link
G Dst dystonin decreases expression ISO tamibarotene results in decreased expression of DST mRNA CTD PMID:15498508 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
JBrowse link
G Dusp10 dual specificity phosphatase 10 decreases expression ISO tamibarotene results in decreased expression of DUSP10 mRNA CTD PMID:17229644 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716
JBrowse link
G Dvl1 dishevelled segment polarity protein 1 decreases expression ISO tamibarotene results in decreased expression of DVL1 mRNA CTD PMID:15498508 NCBI chr 5:166,456,989...166,468,733
Ensembl chr 5:166,456,686...166,468,664
JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 decreases expression ISO tamibarotene results in decreased expression of DYNC1LI2 mRNA CTD PMID:15498508 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670
JBrowse link
G Eci1 enoyl-CoA delta isomerase 1 affects expression ISO tamibarotene affects the expression of ECI1 mRNA CTD PMID:15498508 NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061
JBrowse link
G Edn1 endothelin 1 increases expression ISO tamibarotene results in increased expression of EDN1 mRNA CTD PMID:15498508 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Edn2 endothelin 2 increases expression ISO tamibarotene results in increased expression of EDN2 mRNA CTD PMID:15498508 NCBI chr 5:133,751,316...133,756,814
Ensembl chr 5:133,751,217...133,756,814
JBrowse link
G Edrf1 erythroid differentiation regulatory factor 1 decreases expression ISO tamibarotene results in decreased expression of EDRF1 mRNA CTD PMID:15498508 NCBI chr 1:188,441,514...188,478,743
Ensembl chr 1:188,441,634...188,478,701
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO tamibarotene results in increased expression of EEF1A1 mRNA CTD PMID:15498508 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Eef1e1 eukaryotic translation elongation factor 1 epsilon 1 decreases expression ISO tamibarotene results in decreased expression of EEF1E1 mRNA CTD PMID:15498508 NCBI chr17:26,148,652...26,159,358
Ensembl chr17:26,148,633...26,215,720
JBrowse link
G Egr3 early growth response 3 increases expression ISO tamibarotene results in increased expression of EGR3 mRNA CTD PMID:15498508 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Eif2a eukaryotic translation initiation factor 2A affects expression ISO tamibarotene affects the expression of EIF2A mRNA CTD PMID:15498508 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068
JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma affects expression ISO tamibarotene affects the expression of EIF2S3 mRNA CTD PMID:15498508 NCBI chr  X:58,916,513...58,939,923
Ensembl chr  X:58,917,490...58,940,686
JBrowse link
G Eif3a eukaryotic translation initiation factor 3, subunit A decreases expression ISO tamibarotene results in decreased expression of EIF3A mRNA CTD PMID:15498508 NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
JBrowse link
G Eif4a2 eukaryotic translation initiation factor 4A2 decreases expression ISO tamibarotene results in decreased expression of EIF4A2 mRNA CTD PMID:15498508 NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781
JBrowse link
G Eif4b eukaryotic translation initiation factor 4B decreases expression ISO tamibarotene results in decreased expression of EIF4B mRNA CTD PMID:15498508 NCBI chr 7:133,206,637...133,228,436 JBrowse link
G Epx eosinophil peroxidase decreases expression ISO tamibarotene results in decreased expression of EPX mRNA CTD PMID:15498508 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit decreases expression ISO tamibarotene results in decreased expression of ERCC8 mRNA CTD PMID:15498508 NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859
JBrowse link
G Esr1 estrogen receptor 1 increases activity ISO tamibarotene results in increased activity of ESR1 protein CTD PMID:25257666 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Evx1 even-skipped homeobox 1 decreases expression ISO tamibarotene results in decreased expression of EVX1 mRNA CTD PMID:15498508 NCBI chr 4:81,416,590...81,420,967
Ensembl chr 4:81,416,590...81,420,967
JBrowse link
G Exoc3 exocyst complex component 3 affects expression ISO tamibarotene affects the expression of EXOC3 mRNA CTD PMID:15498508 NCBI chr 1:29,091,298...29,122,056
Ensembl chr 1:29,091,294...29,122,045
JBrowse link
G F3 coagulation factor III, tissue factor multiple interactions
decreases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in decreased expression of F3 mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in decreased expression of F3 mRNA] CTD PMID:15020266 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
JBrowse link
G Fam89b family with sequence similarity 89, member B increases expression ISO tamibarotene results in increased expression of FAM89B mRNA CTD PMID:15498508 NCBI chr 1:203,015,772...203,017,890
Ensembl chr 1:203,015,773...203,017,367
JBrowse link
G Fas Fas cell surface death receptor increases activity ISO tamibarotene results in increased activity of FAS protein CTD PMID:15703382 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fat1 FAT atypical cadherin 1 affects expression ISO tamibarotene affects the expression of FAT1 mRNA CTD PMID:15498508 NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107
JBrowse link
G Fbn2 fibrillin 2 decreases expression ISO tamibarotene results in decreased expression of FBN2 mRNA CTD PMID:15498508 NCBI chr18:51,499,670...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Fbp1 fructose-bisphosphatase 1 increases expression ISO tamibarotene results in increased expression of FBP1 mRNA CTD PMID:15498508 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Fcer1g Fc epsilon receptor Ig increases expression ISO tamibarotene results in increased expression of FCER1G mRNA CTD PMID:15498508 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443
JBrowse link
G Fcgr1a Fc gamma receptor 1A affects expression ISO tamibarotene affects the expression of FCGR1A mRNA CTD PMID:15498508 NCBI chr 2:183,851,075...183,860,077
Ensembl chr 2:183,851,077...183,859,994
JBrowse link
G Fcgr2b Fc gamma receptor 2B affects expression ISO tamibarotene affects the expression of FCGR2B mRNA CTD PMID:15498508 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778
JBrowse link
G Fes FES proto-oncogene, tyrosine kinase affects expression ISO tamibarotene affects the expression of FES mRNA CTD PMID:15498508 NCBI chr 1:134,337,698...134,346,934
Ensembl chr 1:134,337,698...134,346,934
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO tamibarotene results in decreased expression of FGFR1 mRNA CTD PMID:15498508 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase increases expression ISO tamibarotene results in increased expression of FGR mRNA CTD PMID:15498508 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326
JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 decreases expression ISO tamibarotene results in decreased expression of FKBP5 mRNA CTD PMID:15498508 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674
JBrowse link
G Flot1 flotillin 1 increases expression ISO tamibarotene results in increased expression of FLOT1 mRNA CTD PMID:15498508 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression ISO tamibarotene results in increased expression of FOSB mRNA CTD PMID:15498508 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Foxo4 forkhead box O4 increases expression ISO tamibarotene results in increased expression of FOXO4 mRNA CTD PMID:15498508 NCBI chr  X:66,385,241...66,392,115
Ensembl chr  X:66,385,558...66,392,115
JBrowse link
G Foxp3 forkhead box P3 decreases expression ISO tamibarotene results in decreased expression of FOXP3 mRNA CTD PMID:22077062 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Fuca1 alpha-L-fucosidase 1 increases expression ISO tamibarotene results in increased expression of FUCA1 mRNA CTD PMID:15498508 NCBI chr 5:148,152,718...148,169,972
Ensembl chr 5:148,152,700...148,169,972
JBrowse link
G Fut4 fucosyltransferase 4 increases expression ISO tamibarotene results in increased expression of FUT4 mRNA CTD PMID:15498508 NCBI chr 8:11,586,721...11,590,682
Ensembl chr 8:11,586,721...11,590,682
JBrowse link
G Fyb1 FYN binding protein 1 affects expression ISO tamibarotene affects the expression of FYB1 mRNA CTD PMID:15498508 NCBI chr 2:55,621,585...55,781,206
Ensembl chr 2:55,632,698...55,779,629
JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase decreases expression ISO tamibarotene results in decreased expression of FYN mRNA CTD PMID:15498508 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha decreases expression ISO tamibarotene results in decreased expression of GADD45A mRNA CTD PMID:15498508 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
JBrowse link
G Galk2 galactokinase 2 decreases expression ISO tamibarotene results in decreased expression of GALK2 mRNA CTD PMID:15498508 NCBI chr 3:113,110,057...113,243,014
Ensembl chr 3:113,110,030...113,233,306
JBrowse link
G Galt galactose-1-phosphate uridylyltransferase increases expression ISO tamibarotene results in increased expression of GALT mRNA CTD PMID:15498508 NCBI chr 5:56,927,039...56,930,284
Ensembl chr 5:56,926,724...56,930,265
JBrowse link
G Gata2 GATA binding protein 2 decreases expression ISO tamibarotene results in decreased expression of GATA2 mRNA CTD PMID:15498508 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gatad1 GATA zinc finger domain containing 1 decreases expression ISO tamibarotene results in decreased expression of GATAD1 mRNA CTD PMID:15498508 NCBI chr 4:30,507,530...30,519,107
Ensembl chr 4:30,507,538...30,519,107
JBrowse link
G Gatc glutamyl-tRNA amidotransferase subunit C affects expression ISO tamibarotene affects the expression of GATC mRNA CTD PMID:15498508 NCBI chr12:41,270,096...41,278,067
Ensembl chr12:41,270,087...41,277,995
JBrowse link
G Gca grancalcin increases expression ISO tamibarotene results in increased expression of GCA mRNA CTD PMID:15498508 NCBI chr 3:47,297,320...47,329,913
Ensembl chr 3:47,297,383...47,328,581
JBrowse link
G Gfap glial fibrillary acidic protein increases expression EXP tamibarotene results in increased expression of GFAP CTD PMID:19182380 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gfpt1 glutamine fructose-6-phosphate transaminase 1 affects expression ISO tamibarotene affects the expression of GFPT1 mRNA CTD PMID:15498508 NCBI chr 4:119,496,691...119,546,472
Ensembl chr 4:119,496,714...119,546,471
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 increases expression ISO tamibarotene results in increased expression of GGT1 mRNA CTD PMID:15498508 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Glod4 glyoxalase domain containing 4 affects expression ISO tamibarotene affects the expression of GLOD4 mRNA CTD PMID:15498508 NCBI chr10:61,077,535...61,095,876
Ensembl chr10:61,066,421...61,095,898
JBrowse link
G Glrx glutaredoxin increases expression ISO tamibarotene results in increased expression of GLRX mRNA CTD PMID:15498508 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gnaq G protein subunit alpha q affects expression ISO tamibarotene affects the expression of GNAQ mRNA CTD PMID:15498508 NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672
JBrowse link
G Gng4 G protein subunit gamma 4 decreases expression ISO tamibarotene results in decreased expression of GNG4 mRNA CTD PMID:15498508 NCBI chr17:86,448,708...86,497,560
Ensembl chr17:86,449,022...86,495,254
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression ISO tamibarotene affects the expression of GPX1 mRNA CTD PMID:15498508 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 increases expression
affects expression
ISO tamibarotene results in increased expression of GRINA mRNA
tamibarotene affects the expression of GRINA mRNA
CTD PMID:15498508 PMID:17229644 NCBI chr 7:107,962,194...107,965,372
Ensembl chr 7:107,962,207...107,965,366
JBrowse link
G Grn granulin precursor increases expression ISO tamibarotene results in increased expression of GRN mRNA CTD PMID:15498508 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta affects expression ISO tamibarotene affects the expression of GSK3B mRNA CTD PMID:15498508 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsn gelsolin increases expression ISO tamibarotene results in increased expression of GSN mRNA CTD PMID:15498508 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression ISO tamibarotene results in increased expression of GSTM1 mRNA CTD PMID:15498508 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gsto1 glutathione S-transferase omega 1 increases expression ISO tamibarotene results in increased expression of GSTO1 mRNA CTD PMID:15498508 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G H2ac18 H2A clustered histone 18 increases expression ISO tamibarotene results in increased expression of H2AC18 mRNA CTD PMID:15498508 NCBI chr 2:183,808,398...183,808,992 JBrowse link
G H4c3 H4 clustered histone 3 affects expression ISO tamibarotene affects the expression of H4C3 mRNA CTD PMID:15498508
G H4f3 H1.3 linker histone, cluster member affects expression ISO tamibarotene affects the expression of H1-3 mRNA CTD PMID:15498508 NCBI chr17:41,551,524...41,552,303
Ensembl chr17:41,529,667...41,552,334
JBrowse link
G Hck HCK proto-oncogene, Src family tyrosine kinase increases expression ISO tamibarotene results in increased expression of HCK mRNA CTD PMID:15498508 NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693
JBrowse link
G Hipk1 homeodomain interacting protein kinase 1 decreases expression ISO tamibarotene results in decreased expression of HIPK1 mRNA CTD PMID:15498508 NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902
JBrowse link
G Hira histone cell cycle regulator affects expression ISO tamibarotene affects the expression of HIRA mRNA CTD PMID:15498508 NCBI chr11:82,024,469...82,133,212
Ensembl chr11:82,024,469...82,133,529
JBrowse link
G Hk3 hexokinase 3 increases expression ISO tamibarotene results in increased expression of HK3 mRNA CTD PMID:15498508 NCBI chr17:9,596,950...9,614,847
Ensembl chr17:9,599,865...9,614,863
JBrowse link
G Hlx H2.0-like homeobox affects expression ISO tamibarotene affects the expression of HLX mRNA CTD PMID:15498508 NCBI chr13:96,280,335...96,285,750
Ensembl chr13:96,280,339...96,285,750
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 affects expression ISO tamibarotene affects the expression of HMGCS1 mRNA CTD PMID:15498508 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hpd 4-hydroxyphenylpyruvate dioxygenase increases expression ISO tamibarotene results in increased expression of HPD mRNA CTD PMID:15498508 NCBI chr12:33,381,397...33,392,750
Ensembl chr12:33,381,231...33,392,766
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase affects expression ISO tamibarotene affects the expression of HPGD mRNA CTD PMID:15498508 NCBI chr16:33,986,265...34,024,228
Ensembl chr16:33,986,266...34,024,228
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 affects expression ISO tamibarotene affects the expression of HSP90AB1 mRNA CTD PMID:15498508 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 decreases expression ISO tamibarotene results in decreased expression of HSP90B1 mRNA CTD PMID:15498508 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Ice1 interactor of little elongation complex ELL subunit 1 affects expression ISO tamibarotene affects the expression of ICE1 mRNA CTD PMID:15498508 NCBI chr 1:32,640,372...32,682,669
Ensembl chr 1:32,640,407...32,679,898
JBrowse link
G Ier3 immediate early response 3 increases expression ISO tamibarotene results in increased expression of IER3 mRNA CTD PMID:15498508 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Ifi35 interferon-induced protein 35 increases expression ISO tamibarotene results in increased expression of IFI35 mRNA CTD PMID:15498508 NCBI chr10:86,381,023...86,389,279
Ensembl chr10:86,381,010...86,389,952
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression ISO tamibarotene results in increased expression of IFIT3 mRNA CTD PMID:15498508 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
JBrowse link
G Ifng interferon gamma multiple interactions
decreases expression
increases response to substance
ISO
EXP
tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG protein]
tamibarotene inhibits the reaction [MBP results in increased expression of IFNG mRNA]
tamibarotene results in decreased expression of IFNG mRNA
IFNG results in increased susceptibility to tamibarotene
tamibarotene results in decreased expression of IFNG; tamibarotene results in decreased expression of IFNG protein
CTD PMID:10828746 PMID:11043609 PMID:11501064 PMID:20861477 PMID:22077062 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 affects expression ISO tamibarotene affects the expression of IGFBP2 mRNA CTD PMID:15498508 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO tamibarotene results in increased expression of IGFBP3 mRNA; tamibarotene results in increased expression of IGFBP3 protein CTD PMID:10766424 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083
JBrowse link
G Ighg1 immunoglobulin heavy constant gamma 1 affects expression ISO tamibarotene affects the expression of IGHG1 mRNA CTD PMID:15498508 Ensembl chr 6:132,389,370...132,393,397 JBrowse link
G Ikzf1 IKAROS family zinc finger 1 affects expression ISO tamibarotene affects the expression of IKZF1 mRNA CTD PMID:15498508 NCBI chr14:86,255,065...86,340,839
Ensembl chr14:86,255,065...86,342,416
JBrowse link
G Il10 interleukin 10 multiple interactions EXP tamibarotene inhibits the reaction [MBP results in increased expression of IL10 mRNA] CTD PMID:11501064 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il10rb interleukin 10 receptor subunit beta increases expression ISO tamibarotene results in increased expression of IL10RB mRNA CTD PMID:15498508 NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074
JBrowse link
G Il17a interleukin 17A multiple interactions ISO IL17A affects the reaction [tamibarotene results in decreased expression of TGFB1 mRNA] CTD PMID:22077062 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il17rd interleukin 17 receptor D decreases expression ISO tamibarotene results in decreased expression of IL17RD mRNA CTD PMID:20861477 NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556
JBrowse link
G Il1b interleukin 1 beta multiple interactions
decreases expression
increases expression
ISO tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 protein]
tamibarotene results in decreased expression of IL1B mRNA
tamibarotene results in increased expression of IL1B mRNA
CTD PMID:9873234 PMID:15498508 PMID:20861477 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il21 interleukin 21 multiple interactions ISO tamibarotene inhibits the reaction [[Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL21 protein] CTD PMID:22077062 NCBI chr 2:120,117,105...120,127,012
Ensembl chr 2:120,119,444...120,126,996
JBrowse link
G Il27 interleukin 27 decreases expression ISO tamibarotene results in decreased expression of IL27 mRNA CTD PMID:20861477 NCBI chr 1:181,173,108...181,178,720
Ensembl chr 1:181,173,372...181,178,582
JBrowse link
G Il2rg interleukin 2 receptor subunit gamma decreases expression ISO tamibarotene results in decreased expression of IL2RG mRNA CTD PMID:20861477 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823
JBrowse link
G Il4 interleukin 4 multiple interactions EXP HX 600 promotes the reaction [tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein]]; LE 540 inhibits the reaction [tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein]]; tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 mRNA]; tamibarotene inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased expression of IL4 protein] CTD PMID:11233995 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
ISO
EXP
tamibarotene inhibits the reaction [AGT protein results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [AGT protein results in increased secretion of IL6 protein]; tamibarotene inhibits the reaction [Lipopolysaccharides results in increased expression of IL6]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of IL6 protein]
tamibarotene results in decreased expression of IL6 mRNA
tamibarotene affects the reaction [MBP results in increased expression of IL6 mRNA]
tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [IL1B results in increased expression of IL6 protein]
CTD PMID:9873234 PMID:10828746 PMID:11043609 PMID:11501064 PMID:16484594 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Il6r interleukin 6 receptor decreases expression ISO tamibarotene results in decreased expression of IL6RA protein CTD PMID:20861477 NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
JBrowse link
G Il7 interleukin 7 decreases expression ISO tamibarotene results in decreased expression of IL7 mRNA CTD PMID:20861477 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075
JBrowse link
G Il7r interleukin 7 receptor decreases expression ISO tamibarotene results in decreased expression of IL7R mRNA CTD PMID:20861477 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757
JBrowse link
G Ilf3 interleukin enhancer binding factor 3 decreases expression ISO tamibarotene results in decreased expression of ILF3 mRNA CTD PMID:15498508 NCBI chr 8:19,922,409...19,960,495
Ensembl chr 8:19,922,460...19,960,350
JBrowse link
G Ilk integrin-linked kinase increases expression ISO tamibarotene results in increased expression of ILK mRNA CTD PMID:15498508 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140
JBrowse link
G Ipo5 importin 5 affects expression ISO tamibarotene affects the expression of IPO5 mRNA CTD PMID:15498508 NCBI chr15:97,990,755...98,041,074
Ensembl chr15:98,005,299...98,041,126
JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 increases expression ISO tamibarotene results in increased expression of IRAK2 mRNA CTD PMID:17229644 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression ISO tamibarotene results in increased expression of IRF1 mRNA CTD PMID:15498508 PMID:17229644 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irf7 interferon regulatory factor 7 increases expression ISO tamibarotene results in increased expression of IRF7 mRNA CTD PMID:15498508 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Irf9 interferon regulatory factor 9 increases expression ISO tamibarotene results in increased expression of IRF9 mRNA CTD PMID:15498508 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236
JBrowse link
G Isg15 ISG15 ubiquitin-like modifier affects expression ISO tamibarotene affects the expression of ISG15 mRNA CTD PMID:15498508 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435
JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 affects expression ISO tamibarotene affects the expression of ISG20 mRNA CTD PMID:15498508 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO tamibarotene results in increased expression of ITGA3 mRNA CTD PMID:17229644 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itga4 integrin subunit alpha 4 affects expression ISO tamibarotene affects the expression of ITGA4 mRNA CTD PMID:15498508 NCBI chr 3:64,162,764...64,235,010
Ensembl chr 3:64,163,085...64,233,715
JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
affects expression
ISO tamibarotene results in increased expression of ITGAM mRNA; tamibarotene results in increased expression of ITGAM protein
CSF3 protein inhibits the reaction [tamibarotene results in increased expression of ITGAM mRNA]; Triiodothyronine promotes the reaction [tamibarotene results in increased expression of ITGAM protein]
tamibarotene affects the expression of ITGAM protein
CTD PMID:11201846 PMID:15498508 PMID:21393419 PMID:27737899 NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgb2 integrin subunit beta 2 increases expression
multiple interactions
decreases expression
ISO tamibarotene results in increased expression of ITGB2 mRNA
CSF3 protein inhibits the reaction [tamibarotene results in decreased expression of ITGB2 mRNA]; tamibarotene inhibits the reaction [CSF3 protein results in increased expression of ITGB2 mRNA]
CTD PMID:15498508 PMID:27737899 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
JBrowse link
G Itgb7 integrin subunit beta 7 increases expression ISO tamibarotene results in increased expression of ITGB7 mRNA CTD PMID:15498508 PMID:17229644 NCBI chr 7:133,347,927...133,364,955
Ensembl chr 7:133,347,960...133,364,876
JBrowse link
G Itpr2 inositol 1,4,5-trisphosphate receptor, type 2 affects expression ISO tamibarotene affects the expression of ITPR2 mRNA CTD PMID:15498508 NCBI chr 4:179,028,594...179,434,657
Ensembl chr 4:179,027,281...179,404,164
JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor, type 3 decreases expression ISO tamibarotene results in decreased expression of ITPR3 mRNA CTD PMID:15498508 NCBI chr20:5,136,968...5,202,339
Ensembl chr20:5,136,441...5,202,337
JBrowse link
G Jak1 Janus kinase 1 affects expression ISO tamibarotene affects the expression of JAK1 mRNA CTD PMID:15498508 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jak3 Janus kinase 3 decreases expression ISO tamibarotene results in decreased expression of JAK3 mRNA CTD PMID:20861477 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Kat5 lysine acetyltransferase 5 increases expression ISO tamibarotene results in increased expression of KAT5 mRNA CTD PMID:15498508 NCBI chr 1:202,895,751...202,903,178
Ensembl chr 1:202,895,751...202,903,458
JBrowse link
G Kcnab2 potassium voltage-gated channel subfamily A regulatory beta subunit 2 affects expression ISO tamibarotene affects the expression of KCNAB2 mRNA CTD PMID:15498508 NCBI chr 5:162,899,511...162,988,057
Ensembl chr 5:162,901,896...162,988,243
JBrowse link
G Kdm5b lysine demethylase 5B affects expression ISO tamibarotene affects the expression of KDM5B mRNA CTD PMID:15498508 NCBI chr13:46,001,589...46,073,868
Ensembl chr13:46,002,542...46,073,872
JBrowse link
G Kif2a kinesin family member 2A decreases expression ISO tamibarotene results in decreased expression of KIF2A mRNA CTD PMID:15498508 NCBI chr 2:38,367,998...38,431,237
Ensembl chr 2:38,367,998...38,431,508
JBrowse link
G Klf10 KLF transcription factor 10 decreases expression ISO tamibarotene results in decreased expression of KLF10 mRNA CTD PMID:15498508 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klf5 KLF transcription factor 5 multiple interactions ISO tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to [RARA protein binds to RXRA protein]]; tamibarotene inhibits the reaction [KLF5 protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [KLF5 results in increased expression of PDGFA mRNA] CTD PMID:16224062 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klf9 KLF transcription factor 9 decreases expression ISO tamibarotene results in decreased expression of KLF9 mRNA CTD PMID:15498508 NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037
JBrowse link
G Kmt2b lysine methyltransferase 2B affects expression ISO tamibarotene affects the expression of KMT2B mRNA CTD PMID:15498508 NCBI chr 1:85,821,700...85,840,987
Ensembl chr 1:85,821,753...85,841,326
JBrowse link
G Lamc1 laminin subunit gamma 1 decreases expression ISO tamibarotene results in decreased expression of LAMC1 mRNA CTD PMID:15498508 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression ISO tamibarotene results in increased expression of LASP1 mRNA CTD PMID:15498508 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
JBrowse link
G Lck LCK proto-oncogene, Src family tyrosine kinase increases expression ISO tamibarotene results in increased expression of LCK mRNA CTD PMID:15498508 NCBI chr 5:141,888,318...141,916,945
Ensembl chr 5:141,888,326...141,903,794
JBrowse link
G Lcp2 lymphocyte cytosolic protein 2 increases expression ISO tamibarotene results in increased expression of LCP2 mRNA CTD PMID:15498508 NCBI chr10:18,642,600...18,689,562
Ensembl chr10:18,642,658...18,689,559
JBrowse link
G Lgals1 galectin 1 increases expression ISO tamibarotene results in increased expression of LGALS1 mRNA CTD PMID:15498508 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
JBrowse link
G Lgals9 galectin 9 increases expression ISO tamibarotene results in increased expression of LGALS9 mRNA CTD PMID:15498508 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
JBrowse link
G Lmnb1 lamin B1 affects expression ISO tamibarotene affects the expression of LMNB1 mRNA CTD PMID:15498508 NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
JBrowse link
G Lpin1 lipin 1 decreases expression ISO tamibarotene results in decreased expression of LPIN1 mRNA CTD PMID:15498508 NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
JBrowse link
G Lrba LPS responsive beige-like anchor protein affects expression ISO tamibarotene affects the expression of LRBA mRNA CTD PMID:15498508 NCBI chr 2:171,623,668...172,202,576
Ensembl chr 2:171,621,507...172,202,724
JBrowse link
G Lsm14a LSM14A mRNA processing body assembly factor decreases expression ISO tamibarotene results in decreased expression of LSM14A mRNA CTD PMID:15498508 NCBI chr 1:86,964,800...87,009,325
Ensembl chr 1:86,964,828...87,009,276
JBrowse link
G Lsp1 lymphocyte-specific protein 1 increases expression ISO tamibarotene results in increased expression of LSP1 mRNA CTD PMID:15498508 NCBI chr 1:197,614,677...197,648,414
Ensembl chr 1:197,614,687...197,648,416
JBrowse link
G Lst1 leukocyte specific transcript 1 increases expression ISO tamibarotene results in increased expression of LST1 mRNA CTD PMID:15498508 NCBI chr20:3,634,680...3,639,731
Ensembl chr20:3,634,749...3,637,997
JBrowse link
G Ltb4r leukotriene B4 receptor affects expression ISO tamibarotene affects the expression of LTB4R mRNA CTD PMID:15498508 NCBI chr15:29,263,199...29,265,716 JBrowse link
G Ly6e lymphocyte antigen 6 family member E increases expression ISO tamibarotene results in increased expression of LY6E mRNA CTD PMID:15498508 NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase increases expression ISO tamibarotene results in increased expression of LYN mRNA CTD PMID:15498508 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
JBrowse link
G Lztfl1 leucine zipper transcription factor-like 1 increases expression ISO tamibarotene results in increased expression of LZTFL1 mRNA CTD PMID:17229644 NCBI chr 8:123,344,085...123,360,245
Ensembl chr 8:123,344,925...123,360,192
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 affects expression ISO tamibarotene affects the expression of MACF1 mRNA CTD PMID:15498508 NCBI chr 5:135,623,734...135,949,097
Ensembl chr 5:135,623,742...135,945,905
JBrowse link
G Macir macrophage immunometabolism regulator decreases expression ISO tamibarotene results in decreased expression of MACIR mRNA CTD PMID:15498508 NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733
JBrowse link
G Map4k1 mitogen activated protein kinase kinase kinase kinase 1 increases expression ISO tamibarotene results in increased expression of MAP4K1 mRNA CTD PMID:17229644 NCBI chr 1:84,270,951...84,292,496
Ensembl chr 1:84,271,069...84,292,493
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
ISO
EXP
[tamibarotene co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in decreased phosphorylation of and results in decreased activity of MAPK1 protein; tamibarotene promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of and results in decreased activity of MAPK1 protein]
tamibarotene results in increased phosphorylation of MAPK1 protein
BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK1 protein]
CTD PMID:15020266 PMID:19457078 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression ISO tamibarotene affects the expression of MAPK14 mRNA CTD PMID:15498508 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases phosphorylation
ISO
EXP
[tamibarotene co-treated with 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one] results in decreased phosphorylation of and results in decreased activity of MAPK3 protein; tamibarotene promotes the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of and results in decreased activity of MAPK3 protein]
tamibarotene results in increased phosphorylation of MAPK3 protein
BDNF affects the reaction [tamibarotene results in increased phosphorylation of MAPK3 protein]
CTD PMID:15020266 PMID:19457078 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression ISO tamibarotene results in increased expression of MAPKAPK2 mRNA CTD PMID:17229644 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457
JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO tamibarotene results in decreased expression of MAT2A mRNA CTD PMID:15498508 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493
JBrowse link
G Mbp myelin basic protein multiple interactions
increases expression
EXP tamibarotene affects the reaction [MBP results in increased expression of IL6 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of IFNG mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of IL10 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of NOS2 mRNA]; tamibarotene inhibits the reaction [MBP results in increased expression of TNF mRNA]
tamibarotene results in increased expression of MBP
CTD PMID:11501064 PMID:19182380 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
JBrowse link
G Mdk midkine increases expression ISO tamibarotene results in increased expression of MDK mRNA CTD PMID:17229644 NCBI chr 3:77,901,134...77,903,997
Ensembl chr 3:77,901,158...77,903,130
JBrowse link
G Mdm1 Mdm1 nuclear protein decreases expression ISO tamibarotene results in decreased expression of MDM1 mRNA CTD PMID:15498508 NCBI chr 7:53,729,603...53,766,034
Ensembl chr 7:53,729,610...53,766,034
JBrowse link
G Mdn1 midasin AAA ATPase 1 affects expression ISO tamibarotene affects the expression of MDN1 mRNA CTD PMID:15498508 NCBI chr 5:47,055,435...47,190,426
Ensembl chr 5:47,055,447...47,186,332
JBrowse link
G Med21 mediator complex subunit 21 affects expression ISO tamibarotene affects the expression of MED21 mRNA CTD PMID:15498508 NCBI chr 4:179,560,509...179,583,811
Ensembl chr 4:179,560,579...179,567,548
JBrowse link
G Mfap3 microfibril associated protein 3 affects expression ISO tamibarotene affects the expression of MFAP3 mRNA CTD PMID:15498508 NCBI chr10:41,696,788...41,711,490
Ensembl chr10:41,696,771...41,710,406
JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing increases expression ISO tamibarotene results in increased expression of MFGE8 mRNA CTD PMID:17229644 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073
JBrowse link
G Morc2 MORC family CW-type zinc finger 2 decreases expression ISO tamibarotene results in decreased expression of MORC2 mRNA CTD PMID:15498508 NCBI chr14:78,529,603...78,571,375
Ensembl chr14:78,527,009...78,571,343
JBrowse link
G Msh6 mutS homolog 6 decreases expression ISO tamibarotene results in decreased expression of MSH6 mRNA CTD PMID:15498508 NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956
JBrowse link
G Msi1 musashi RNA-binding protein 1 affects expression ISO tamibarotene affects the expression of MSI1 mRNA CTD PMID:15498508 NCBI chr12:41,158,301...41,251,134
Ensembl chr12:41,158,599...41,191,076
JBrowse link
G Msr1 macrophage scavenger receptor 1 multiple interactions ISO tamibarotene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of MSR1 mRNA] CTD PMID:16484594 NCBI chr16:52,717,775...52,803,602
Ensembl chr16:52,717,732...52,799,676
JBrowse link
G Mt1 metallothionein 1 increases expression ISO tamibarotene results in increased expression of MT1A mRNA CTD PMID:15498508 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
JBrowse link
G Mt3 metallothionein 3 affects expression ISO tamibarotene affects the expression of MT3 mRNA CTD PMID:15498508 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mta1 metastasis associated 1 decreases expression ISO tamibarotene results in decreased expression of MTA1 mRNA CTD PMID:15498508 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641
JBrowse link
G Mtg1 mitochondrial ribosome-associated GTPase 1 affects expression ISO tamibarotene affects the expression of MTG1 mRNA CTD PMID:15498508 NCBI chr 1:194,931,543...194,944,278
Ensembl chr 1:194,931,531...194,944,277
JBrowse link
G Mtmr6 myotubularin related protein 6 decreases expression ISO tamibarotene results in decreased expression of MTMR6 mRNA CTD PMID:15498508 NCBI chr15:34,419,931...34,457,863
Ensembl chr15:34,419,903...34,457,861
JBrowse link
G Mx2 MX dynamin like GTPase 2 affects expression ISO tamibarotene affects the expression of MX2 mRNA CTD PMID:15498508 NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
JBrowse link
G Myb MYB proto-oncogene, transcription factor affects expression ISO tamibarotene affects the expression of MYB mRNA CTD PMID:15498508 NCBI chr 1:15,939,771...15,973,367
Ensembl chr 1:15,939,761...15,973,057
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO tamibarotene results in decreased expression of MYC mRNA CTD PMID:15498508 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor increases expression ISO tamibarotene results in increased expression of MYD88 mRNA CTD PMID:15498508 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G N4bp2l2 NEDD4 binding protein 2-like 2 decreases expression ISO tamibarotene results in decreased expression of N4BP2L2 mRNA CTD PMID:15498508 NCBI chr12:137,342...200,292
Ensembl chr12:103,590...197,784
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO tamibarotene results in decreased expression of NAP1L1 mRNA CTD PMID:15498508 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 decreases expression ISO tamibarotene results in decreased expression of NCBP2 mRNA CTD PMID:15498508 NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression ISO tamibarotene results in increased expression of NCF1 mRNA CTD PMID:15498508 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
JBrowse link
G Nck1 NCK adaptor protein 1 affects expression ISO tamibarotene affects the expression of NCK1 mRNA CTD PMID:15498508 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300
JBrowse link
G Ncoa6 nuclear receptor coactivator 6 decreases expression ISO tamibarotene results in decreased expression of NCOA6 mRNA CTD PMID:15498508 NCBI chr 3:143,890,896...143,961,916
Ensembl chr 3:143,890,896...143,952,268
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 increases expression ISO tamibarotene results in increased expression of NCOR2 mRNA CTD PMID:17229644 NCBI chr12:31,466,418...31,628,319
Ensembl chr12:31,466,412...31,628,319
JBrowse link
G Nemp1 nuclear envelope integral membrane protein 1 decreases expression ISO tamibarotene results in decreased expression of NEMP1 mRNA CTD PMID:15498508 NCBI chr 7:63,514,025...63,538,791
Ensembl chr 7:63,479,951...63,534,602
JBrowse link
G Nfe2 nuclear factor, erythroid 2 increases expression ISO tamibarotene results in increased expression of NFE2 mRNA CTD PMID:15498508 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression ISO tamibarotene results in decreased expression of NFE2L2 mRNA CTD PMID:15498508 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfyb nuclear transcription factor Y subunit beta decreases expression ISO tamibarotene results in decreased expression of NFYB mRNA CTD PMID:15498508 NCBI chr 7:20,964,988...20,980,569
Ensembl chr 7:20,964,993...20,980,565
JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 increases expression ISO tamibarotene results in increased expression of NHERF1 mRNA CTD PMID:15498508 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Nipsnap1 nipsnap homolog 1 increases expression ISO tamibarotene results in increased expression of NIPSNAP1 mRNA CTD PMID:15498508 NCBI chr14:79,734,234...79,758,101
Ensembl chr14:79,734,209...79,758,098
JBrowse link
G Nkg7 natural killer cell granule protein 7 increases expression ISO tamibarotene results in increased expression of NKG7 mRNA CTD PMID:15498508 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983
JBrowse link
G Nkrf NFKB repressing factor increases expression ISO tamibarotene results in increased expression of NKRF mRNA CTD PMID:20861477 NCBI chr  X:116,126,341...116,144,554
Ensembl chr  X:116,128,798...116,144,628
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP tamibarotene inhibits the reaction [MBP results in increased expression of NOS2 mRNA] CTD PMID:11501064 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npc2 NPC intracellular cholesterol transporter 2 increases expression ISO tamibarotene results in increased expression of NPC2 mRNA CTD PMID:15498508 NCBI chr 6:104,397,239...104,418,161
Ensembl chr 6:104,378,644...104,418,155
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 increases activity
multiple interactions
ISO tamibarotene results in increased activity of NR1H4 protein
tamibarotene inhibits the reaction [Chenodeoxycholic Acid results in increased activity of NR1H4 protein]
CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
JBrowse link
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 decreases expression ISO tamibarotene results in decreased expression of NR2F2 mRNA CTD PMID:15498508 NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions
increases expression
increases phosphorylation
ISO
EXP
[tamibarotene co-treated with BDNF] results in increased expression of NTRK2
tamibarotene results in increased expression of NTRK2
BDNF affects the reaction [tamibarotene results in increased phosphorylation of NTRK2 protein]
CTD PMID:19182380 PMID:19457078 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136
JBrowse link
G Nudt21 nudix hydrolase 21 affects expression ISO tamibarotene affects the expression of NUDT21 mRNA CTD PMID:15498508 NCBI chr19:10,974,800...10,993,841
Ensembl chr19:10,974,241...10,991,682
JBrowse link
G Nutf2 nuclear transport factor 2 affects expression ISO tamibarotene affects the expression of NUTF2 mRNA CTD PMID:15498508 NCBI chr19:33,752,319...33,773,595
Ensembl chr19:33,752,291...33,773,591
JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A affects expression ISO tamibarotene affects the expression of OAS1 mRNA CTD PMID:15498508 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517
JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO tamibarotene results in increased expression of OAS2 mRNA CTD PMID:15498508 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression ISO tamibarotene results in increased expression of OASL mRNA CTD PMID:15498508 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
JBrowse link
G Ocln occludin increases expression ISO tamibarotene results in increased expression of OCLN mRNA CTD PMID:16982755 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression ISO tamibarotene results in decreased expression of ODC1 mRNA CTD PMID:15498508 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
JBrowse link
G Oga O-GlcNAcase decreases expression ISO tamibarotene results in decreased expression of OGA mRNA CTD PMID:15498508 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359
JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression ISO tamibarotene results in increased expression of OGG1 mRNA CTD PMID:15498508 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766
JBrowse link
G Ogt O-linked N-acetylglucosamine (GlcNAc) transferase decreases expression ISO tamibarotene results in decreased expression of OGT mRNA CTD PMID:15498508 NCBI chr  X:66,771,278...66,816,148
Ensembl chr  X:66,771,349...66,816,146
JBrowse link
G Orc2 origin recognition complex, subunit 2 decreases expression ISO tamibarotene results in decreased expression of ORC2 mRNA CTD PMID:15498508 NCBI chr 9:60,001,631...60,038,301
Ensembl chr 9:60,001,910...60,038,195
JBrowse link
G P2rx5 purinergic receptor P2X 5 increases expression ISO tamibarotene results in increased expression of P2RX5 mRNA CTD PMID:17229644 NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
JBrowse link
G P2ry14 purinergic receptor P2Y14 increases expression ISO tamibarotene results in increased expression of P2RY14 mRNA CTD PMID:15498508 NCBI chr 2:143,372,697...143,413,213
Ensembl chr 2:143,372,697...143,413,141
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 increases expression ISO tamibarotene results in increased expression of PAK1 mRNA CTD PMID:15498508 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383
JBrowse link
G Pak2 p21 (RAC1) activated kinase 2 affects expression ISO tamibarotene affects the expression of PAK2 mRNA CTD PMID:15498508 NCBI chr11:68,707,940...68,768,816
Ensembl chr11:68,707,969...68,768,816
JBrowse link
G Pakap paralemmin A kinase anchor protein affects expression ISO tamibarotene affects the expression of PALM2AKAP2 mRNA CTD PMID:15498508 NCBI chr 5:72,536,986...72,648,524
NCBI chr 5:72,313,646...72,450,645
Ensembl chr 5:72,181,718...72,648,524
JBrowse link
G Pank3 pantothenate kinase 3 affects expression ISO tamibarotene affects the expression of PANK3 mRNA CTD PMID:15498508 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955
JBrowse link
G Papola poly (A) polymerase alpha affects expression ISO tamibarotene affects the expression of PAPOLA mRNA CTD PMID:15498508 NCBI chr 6:124,682,015...124,734,706
Ensembl chr 6:124,682,105...124,734,468
JBrowse link
G Pcdh1 protocadherin 1 affects expression ISO tamibarotene affects the expression of PCDH1 mRNA CTD PMID:15498508 NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,013,185...30,039,318
JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 affects expression ISO tamibarotene affects the expression of PCMT1 mRNA CTD PMID:15498508 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201
JBrowse link
G Pcna proliferating cell nuclear antigen affects expression ISO tamibarotene affects the expression of PCNA mRNA CTD PMID:15498508 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [KLF5 results in increased expression of PDGFA mRNA]; tamibarotene inhibits the reaction [RARA protein binds to PDGFA promoter]; tamibarotene inhibits the reaction [RXRA protein binds to PDGFA promoter] CTD PMID:16224062 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdhx pyruvate dehydrogenase complex, component X affects expression ISO tamibarotene affects the expression of PDHX mRNA CTD PMID:15498508 NCBI chr 3:89,372,248...89,431,779
Ensembl chr 3:89,371,497...89,431,773
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO tamibarotene results in increased expression of PGD mRNA CTD PMID:15498508 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778
JBrowse link
G Phyhip phytanoyl-CoA 2-hydroxylase interacting protein decreases expression ISO tamibarotene results in decreased expression of PHYHIP mRNA CTD PMID:15498508 NCBI chr15:45,533,974...45,545,223
Ensembl chr15:45,533,974...45,545,221
JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta affects expression ISO tamibarotene affects the expression of PIK3CB mRNA CTD PMID:15498508 NCBI chr 8:99,594,600...99,699,772
Ensembl chr 8:99,594,644...99,699,663
JBrowse link
G Pik3cd phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta increases expression ISO tamibarotene results in increased expression of PIK3CD mRNA CTD PMID:15498508 NCBI chr 5:160,094,952...160,142,962
Ensembl chr 5:160,094,952...160,120,930
JBrowse link
G Pik3cg phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma multiple interactions
increases expression
ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of and results in increased activity of PIK3CG protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of PIK3CG mRNA]; tamibarotene results in increased expression of and results in increased activity of PIK3CG protein CTD PMID:15020266 PMID:15498508 NCBI chr 6:48,766,778...48,802,098
Ensembl chr 6:48,766,864...48,802,043
JBrowse link
G Pikfyve phosphoinositide kinase, FYVE-type zinc finger containing decreases expression ISO tamibarotene results in decreased expression of PIKFYVE mRNA CTD PMID:15498508 NCBI chr 9:66,563,747...66,657,873
Ensembl chr 9:66,563,727...66,657,868
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO tamibarotene results in increased expression of PIM1 mRNA CTD PMID:15498508 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174
JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta affects expression ISO tamibarotene affects the expression of PITPNB mRNA CTD PMID:15498508 NCBI chr12:45,249,308...45,298,388
Ensembl chr12:45,249,333...45,298,314
JBrowse link
G Pkn1 protein kinase N1 increases expression ISO tamibarotene results in increased expression of PKN1 mRNA CTD PMID:15498508 NCBI chr19:24,442,130...24,470,107
Ensembl chr19:24,442,122...24,470,107
JBrowse link
G Pkp4 plakophilin 4 decreases expression ISO tamibarotene results in decreased expression of PKP4 mRNA CTD PMID:15498508 NCBI chr 3:43,632,364...43,835,834
Ensembl chr 3:43,631,880...43,835,474
JBrowse link
G Plek pleckstrin increases expression ISO tamibarotene results in increased expression of PLEK mRNA CTD PMID:15498508 PMID:17229644 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Plk4 polo-like kinase 4 decreases expression ISO tamibarotene results in decreased expression of PLK4 mRNA CTD PMID:15498508 NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO tamibarotene results in increased expression of PLSCR1 mRNA CTD PMID:15498508 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Plxna1 plexin A1 increases expression ISO tamibarotene results in increased expression of PLXNA1 mRNA CTD PMID:17229644 NCBI chr 4:121,737,934...121,782,901
Ensembl chr 4:121,737,945...122,024,196
JBrowse link
G Pnn pinin, desmosome associated protein decreases expression ISO tamibarotene results in decreased expression of PNN mRNA CTD PMID:15498508 NCBI chr 6:76,758,138...76,766,451
Ensembl chr 6:76,758,117...76,766,889
JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression ISO tamibarotene results in increased expression of POLD4 mRNA CTD PMID:15498508 NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression ISO tamibarotene results in increased expression of POR mRNA CTD PMID:15498508 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppat phosphoribosyl pyrophosphate amidotransferase decreases expression ISO tamibarotene results in decreased expression of PPAT mRNA CTD PMID:15498508 NCBI chr14:31,215,741...31,250,144
Ensembl chr14:31,216,165...31,250,144
JBrowse link
G Ppfia1 PTPRF interacting protein alpha 1 decreases expression ISO tamibarotene results in decreased expression of PPFIA1 mRNA CTD PMID:15498508 NCBI chr 1:199,641,277...199,718,371
Ensembl chr 1:199,641,277...199,717,277
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression ISO tamibarotene results in decreased expression of PPP1CB mRNA CTD PMID:15498508 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression ISO tamibarotene results in increased expression of PPP1R15A mRNA CTD PMID:17229644 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta affects expression ISO tamibarotene affects the expression of PPP2R1B mRNA CTD PMID:15498508 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485
JBrowse link
G Prdm2 PR/SET domain 2 affects expression ISO tamibarotene affects the expression of PRDM2 mRNA CTD PMID:15498508 NCBI chr 5:155,421,066...155,531,884
Ensembl chr 5:155,422,134...155,531,825
JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression ISO tamibarotene results in increased expression of PRKACA mRNA CTD PMID:17229644 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430
JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta decreases expression ISO tamibarotene results in decreased expression of PRKACB mRNA CTD PMID:15498508 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198
JBrowse link
G Prkcb protein kinase C, beta increases expression ISO tamibarotene results in increased expression of PRKCB mRNA CTD PMID:15498508 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
JBrowse link
G Prkcd protein kinase C, delta increases expression ISO tamibarotene results in increased expression of PRKCD mRNA CTD PMID:15498508 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352
JBrowse link
G Prkci protein kinase C, iota decreases expression ISO tamibarotene results in decreased expression of PRKCI mRNA CTD PMID:15498508 NCBI chr 2:112,321,919...112,382,305
Ensembl chr 2:112,321,929...112,382,352
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit decreases expression
affects expression
ISO tamibarotene results in decreased expression of PRKDC mRNA
tamibarotene affects the expression of PRKDC mRNA
CTD PMID:15498508 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952
JBrowse link
G Prmt2 protein arginine methyltransferase 2 increases expression ISO tamibarotene results in increased expression of PRMT2 mRNA CTD PMID:15498508 NCBI chr20:12,394,748...12,420,643
Ensembl chr20:12,394,798...12,420,643
JBrowse link
G Prnp prion protein affects expression ISO tamibarotene affects the expression of PRNP mRNA CTD PMID:15498508 NCBI chr 3:119,186,073...119,201,513
Ensembl chr 3:119,177,485...119,203,937
JBrowse link
G Prpf40a pre-mRNA processing factor 40 homolog A affects expression ISO tamibarotene affects the expression of PRPF40A mRNA CTD PMID:15498508 NCBI chr 3:37,625,585...37,689,859
Ensembl chr 3:37,627,690...37,690,886
JBrowse link
G Prps1 phosphoribosyl pyrophosphate synthetase 1 affects expression ISO tamibarotene affects the expression of PRPS1 mRNA CTD PMID:15498508 NCBI chr  X:104,132,139...104,154,191
Ensembl chr  X:104,132,141...104,154,187
JBrowse link
G Prrc2c proline-rich coiled-coil 2C decreases expression ISO tamibarotene results in decreased expression of PRRC2C mRNA CTD PMID:15498508 NCBI chr13:75,003,995...75,073,701
Ensembl chr13:75,004,010...75,073,643
JBrowse link
G Prtn3 proteinase 3 increases expression ISO tamibarotene results in increased expression of PRTN3 mRNA CTD PMID:17229644 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944
JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression ISO tamibarotene results in increased expression of PSMB9 mRNA CTD PMID:15498508 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512
JBrowse link
G Psme2 proteasome activator subunit 2 increases expression ISO tamibarotene results in increased expression of PSME2 mRNA CTD PMID:15498508 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946
JBrowse link
G Ptk2b protein tyrosine kinase 2 beta increases expression ISO tamibarotene results in increased expression of PTK2B mRNA CTD PMID:15498508 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link
G Ptpn3 protein tyrosine phosphatase, non-receptor type 3 affects expression ISO tamibarotene affects the expression of PTPN3 mRNA CTD PMID:15498508 NCBI chr 5:71,908,520...72,027,323
Ensembl chr 5:71,911,135...72,065,443
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C decreases expression ISO tamibarotene results in decreased expression of PTPRC mRNA CTD PMID:17229644 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Ptprf protein tyrosine phosphatase, receptor type, F decreases expression ISO tamibarotene results in decreased expression of PTPRF mRNA CTD PMID:15498508 NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N affects expression ISO tamibarotene affects the expression of PTPRN mRNA CTD PMID:15498508 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190
JBrowse link
G Pum1 pumilio RNA-binding family member 1 decreases expression ISO tamibarotene results in decreased expression of PUM1 mRNA CTD PMID:15498508 NCBI chr 5:142,836,933...142,954,331
Ensembl chr 5:142,837,127...142,954,039
JBrowse link
G Rab1a RAB1A, member RAS oncogene family affects expression ISO tamibarotene affects the expression of RAB1A mRNA CTD PMID:15498508 NCBI chr14:94,422,219...94,448,799
Ensembl chr14:94,415,275...94,448,248
JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression ISO tamibarotene results in increased expression of RAB31 mRNA CTD PMID:15498508 NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
JBrowse link
G Rab35 RAB35, member RAS oncogene family affects expression ISO tamibarotene affects the expression of RAB35 mRNA CTD PMID:15498508 NCBI chr12:40,967,102...40,981,183
Ensembl chr12:40,967,103...40,991,195
JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 decreases expression ISO tamibarotene results in decreased expression of RAB3GAP1 mRNA CTD PMID:15498508 NCBI chr13:39,355,698...39,429,154
Ensembl chr13:39,352,247...39,429,169
JBrowse link
G Rab4a RAB4A, member RAS oncogene family decreases expression ISO tamibarotene results in decreased expression of RAB4A mRNA CTD PMID:15498508 NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703
JBrowse link
G Rab5a RAB5A, member RAS oncogene family affects expression ISO tamibarotene affects the expression of RAB5A mRNA CTD PMID:15498508 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873
JBrowse link
G Rab5c RAB5C, member RAS oncogene family increases expression ISO tamibarotene results in increased expression of RAB5C mRNA CTD PMID:15498508 NCBI chr10:85,642,553...85,666,142
Ensembl chr10:85,642,809...85,666,103
JBrowse link
G Rab6a RAB6A, member RAS oncogene family affects expression ISO tamibarotene affects the expression of RAB6A mRNA CTD PMID:15498508 NCBI chr 1:154,957,870...155,008,922
Ensembl chr 1:154,958,189...154,996,715
JBrowse link
G Rabggtb Rab geranylgeranyltransferase subunit beta decreases expression ISO tamibarotene results in decreased expression of RABGGTB mRNA CTD PMID:15498508 NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050
JBrowse link
G Rad50 RAD50 double strand break repair protein affects expression ISO tamibarotene affects the expression of RAD50 mRNA CTD PMID:15498508 NCBI chr10:37,809,353...37,861,309
Ensembl chr10:37,808,726...37,861,396
JBrowse link
G Rara retinoic acid receptor, alpha multiple interactions
increases expression
decreases response to substance
ISO
EXP
tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to [RARA protein binds to RXRA protein]]; tamibarotene inhibits the reaction [RARA protein binds to PDGFA promoter]
tamibarotene results in increased expression of RARA protein
RARA results in decreased susceptibility to tamibarotene
CTD PMID:16224062 PMID:17611697 PMID:19457078 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta increases expression
multiple interactions
ISO
EXP
tamibarotene results in increased expression of RARB mRNA
CSF3 protein promotes the reaction [tamibarotene results in increased expression of RARB mRNA]; tamibarotene promotes the reaction [CSF3 protein results in increased expression of RARB mRNA]
tamibarotene results in increased expression of RARB protein
CTD PMID:16289102 PMID:19457078 PMID:27737899 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarg retinoic acid receptor, gamma affects expression ISO tamibarotene affects the expression of RARG mRNA CTD PMID:7934625 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Rassf6 Ras association domain family member 6 decreases expression ISO tamibarotene results in decreased expression of RASSF6 mRNA CTD PMID:17229644 NCBI chr14:17,433,328...17,473,565
Ensembl chr14:17,442,789...17,473,330
JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor affects expression ISO tamibarotene affects the expression of RBBP4 mRNA CTD PMID:15498508 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284
JBrowse link
G Rcc1 regulator of chromosome condensation 1 decreases expression ISO tamibarotene results in decreased expression of RCC1 mRNA CTD PMID:15498508 NCBI chr 5:144,526,025...144,544,445
Ensembl chr 5:144,526,025...144,544,577
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit affects expression ISO tamibarotene affects the expression of RELA mRNA CTD PMID:15498508 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit increases expression ISO tamibarotene results in increased expression of RELB mRNA CTD PMID:17229644 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G Rev3l REV3 like, DNA directed polymerase zeta catalytic subunit decreases expression ISO tamibarotene results in decreased expression of REV3L mRNA CTD PMID:15498508 NCBI chr20:43,131,841...43,290,102
Ensembl chr20:43,132,363...43,290,099
JBrowse link
G Rfc5 replication factor C subunit 5 affects expression ISO tamibarotene affects the expression of RFC5 mRNA CTD PMID:15498508 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312
JBrowse link
G Rgs16 regulator of G-protein signaling 16 decreases expression ISO tamibarotene results in decreased expression of RGS16 mRNA CTD PMID:15498508 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Rhbdd3 rhomboid domain containing 3 decreases expression ISO tamibarotene results in decreased expression of RHBDD3 mRNA CTD PMID:15498508 NCBI chr14:79,994,111...80,000,294
Ensembl chr14:79,994,158...80,000,175
JBrowse link
G Rhoq ras homolog family member Q affects expression ISO tamibarotene affects the expression of RHOQ mRNA CTD PMID:15498508 NCBI chr 6:7,613,632...7,652,047 JBrowse link
G Rhou ras homolog family member U decreases expression ISO tamibarotene results in decreased expression of RHOU mRNA CTD PMID:17229644 NCBI chr19:51,641,476...51,651,249
Ensembl chr19:51,641,227...51,650,552
JBrowse link
G Rif1 replication timing regulatory factor 1 decreases expression ISO tamibarotene results in decreased expression of RIF1 mRNA CTD PMID:15498508 NCBI chr 3:36,554,689...36,607,961
Ensembl chr 3:36,554,697...36,603,617
JBrowse link
G Rmnd5a required for meiotic nuclear division 5 homolog A decreases expression ISO tamibarotene results in decreased expression of RMND5A mRNA CTD PMID:15498508 NCBI chr 4:103,375,846...103,432,890
Ensembl chr 4:103,379,908...103,433,051
JBrowse link
G Rnf115 ring finger protein 115 affects expression ISO tamibarotene affects the expression of RNF115 mRNA CTD PMID:15498508 NCBI chr 2:184,262,087...184,329,839
Ensembl chr 2:184,262,371...184,329,823
JBrowse link
G Rnmt RNA (guanine-7-) methyltransferase affects expression ISO tamibarotene affects the expression of RNMT mRNA CTD PMID:15498508 NCBI chr18:61,886,230...61,909,775
Ensembl chr18:61,886,292...61,909,775
JBrowse link
G Rps2 ribosomal protein S2 increases expression ISO tamibarotene results in increased expression of RPS2 mRNA CTD PMID:15498508 NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
JBrowse link
G Rps6ka3 ribosomal protein S6 kinase A3 decreases expression ISO tamibarotene results in decreased expression of RPS6KA3 mRNA CTD PMID:15498508 NCBI chr  X:35,517,306...35,623,296
Ensembl chr  X:35,517,306...35,623,207
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 affects expression ISO tamibarotene affects the expression of RPS6KB1 mRNA CTD PMID:15498508 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 affects expression ISO tamibarotene affects the expression of RRM2 mRNA CTD PMID:15498508 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G RT1-A2 RT1 class Ia, locus A2 increases expression ISO tamibarotene results in increased expression of HLA-E mRNA CTD PMID:15498508 NCBI chr20:4,870,939...4,910,183 JBrowse link
G RT1-Bb RT1 class II, locus Bb increases expression ISO tamibarotene results in increased expression of HLA-DQB1 mRNA CTD PMID:17229644 NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
JBrowse link
G RT1-Da RT1 class II, locus Da increases expression ISO tamibarotene results in increased expression of HLA-DRA mRNA CTD PMID:17229644 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-DMa RT1 class II, locus DMa increases expression ISO tamibarotene results in increased expression of HLA-DMA mRNA CTD PMID:17229644 NCBI chr20:4,707,028...4,710,432
Ensembl chr20:4,707,028...4,710,432
JBrowse link
G RT1-DMb RT1 class II, locus DMb increases expression ISO tamibarotene results in increased expression of HLA-DMB mRNA CTD PMID:17229644 NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340
JBrowse link
G RT1-Ha RT1 class II, locus Ha increases expression ISO tamibarotene results in increased expression of HLA-DPA1 mRNA CTD PMID:17229644 NCBI chr20:4,760,631...4,770,662
Ensembl chr20:4,760,118...4,770,244
JBrowse link
G RT1-M3-1 RT1 class Ib, locus M3, gene 1 increases expression ISO tamibarotene results in increased expression of HLA-G mRNA CTD PMID:15498508 NCBI chr20:1,323,976...1,328,126
Ensembl chr20:1,287,521...1,328,117
JBrowse link
G Rtel1 regulator of telomere elongation helicase 1 affects expression ISO tamibarotene affects the expression of RTEL1 mRNA CTD PMID:15498508 NCBI chr 3:168,427,247...168,465,349
Ensembl chr 3:168,419,579...168,465,348
JBrowse link
G Runx1 RUNX family transcription factor 1 affects expression ISO tamibarotene affects the expression of RUNX1 mRNA CTD PMID:15498508 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542
JBrowse link
G Runx2 RUNX family transcription factor 2 decreases expression ISO tamibarotene results in decreased expression of RUNX2 mRNA CTD PMID:15498508 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO tamibarotene inhibits the reaction [[KLF5 protein binds to [RARA protein binds to RXRA protein]] which binds to PDGFA promoter]; tamibarotene inhibits the reaction [[RARA co-treated with RXRA] promotes the reaction [KLF5 results in increased expression of PDGFA mRNA]]; tamibarotene inhibits the reaction [KLF5 protein binds to [RARA protein binds to RXRA protein]]; tamibarotene inhibits the reaction [RXRA protein binds to PDGFA promoter] CTD PMID:16224062 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G S100a4 S100 calcium-binding protein A4 decreases expression
increases expression
ISO tamibarotene results in decreased expression of S100A4 mRNA
tamibarotene results in increased expression of S100A4 mRNA
CTD PMID:15498508 PMID:17229644 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression ISO tamibarotene results in increased expression of S100A8 mRNA CTD PMID:15498508 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO tamibarotene results in increased expression of S100A9 mRNA CTD PMID:15498508 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Sacs sacsin molecular chaperone decreases expression ISO tamibarotene results in decreased expression of SACS mRNA CTD PMID:15498508 NCBI chr15:35,285,783...35,370,335
Ensembl chr15:35,285,782...35,370,335
JBrowse link
G Sap30 Sin3A associated protein 30 decreases expression ISO tamibarotene results in decreased expression of SAP30 mRNA CTD PMID:15498508 NCBI chr16:32,747,777...32,753,114
Ensembl chr16:32,747,734...32,753,112
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO tamibarotene results in increased expression of SAT1 mRNA CTD PMID:15498508 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Scamp1 secretory carrier membrane protein 1 affects expression ISO tamibarotene affects the expression of SCAMP1 mRNA CTD PMID:15498508 NCBI chr 2:25,433,958...25,516,734
Ensembl chr 2:25,433,959...25,516,673
JBrowse link
G Sccpdh saccharopine dehydrogenase (putative) decreases expression ISO tamibarotene results in decreased expression of SCCPDH mRNA CTD PMID:15498508 NCBI chr13:91,400,120...91,421,875
Ensembl chr13:91,400,190...91,422,222
JBrowse link
G Scd stearoyl-CoA desaturase affects expression ISO tamibarotene affects the expression of SCD mRNA CTD PMID:15498508 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sec16a SEC16 homolog A, endoplasmic reticulum export factor decreases expression ISO tamibarotene results in decreased expression of SEC16A mRNA CTD PMID:15498508 NCBI chr 3:9,229,687...9,264,837
Ensembl chr 3:9,229,687...9,264,273
JBrowse link
G Sec31a SEC31 homolog A, COPII coat complex component decreases expression ISO tamibarotene results in decreased expression of SEC31A mRNA CTD PMID:15498508 NCBI chr14:9,214,324...9,269,281
Ensembl chr14:9,214,349...9,269,273
JBrowse link
G Sell selectin L increases expression ISO tamibarotene results in increased expression of SELL mRNA CTD PMID:15498508 NCBI chr13:76,416,969...76,436,444
Ensembl chr13:76,416,915...76,436,456
JBrowse link
G Septin11 septin 11 affects expression
decreases expression
ISO tamibarotene affects the expression of SEPTIN11 mRNA
tamibarotene results in decreased expression of SEPTIN11 mRNA
CTD PMID:15498508 NCBI chr14:14,844,759...14,990,856
Ensembl chr14:14,844,580...14,990,853
JBrowse link
G Serbp1 Serpine1 mRNA binding protein 1 affects expression ISO tamibarotene affects the expression of SERBP1 mRNA CTD PMID:15498508 NCBI chr 4:96,401,587...96,421,816
Ensembl chr 4:96,401,477...96,421,813
JBrowse link
G Serinc5 serine incorporator 5 decreases expression ISO tamibarotene results in decreased expression of SERINC5 mRNA CTD PMID:15498508 NCBI chr 2:23,846,899...23,950,346
Ensembl chr 2:23,846,900...23,950,346
JBrowse link
G Serpinb10 serpin family B member 10 decreases expression ISO tamibarotene results in decreased expression of SERPINB10 mRNA CTD PMID:15498508 NCBI chr13:23,553,348...23,571,182
Ensembl chr13:23,553,430...23,571,182
JBrowse link
G Serpinb1a serpin family B member 1A increases expression ISO tamibarotene results in increased expression of SERPINB1 mRNA CTD PMID:15498508 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Serpinb2 serpin family B member 2 decreases expression ISO tamibarotene results in decreased expression of SERPINB2 mRNA CTD PMID:15498508 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Serpinb8 serpin family B member 8 affects expression ISO tamibarotene affects the expression of SERPINB8 mRNA CTD PMID:15498508 NCBI chr13:23,626,936...23,650,277
Ensembl chr13:23,626,945...23,650,835
JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression ISO tamibarotene results in decreased expression of SFPQ mRNA CTD PMID:15498508 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sh2b2 SH2B adaptor protein 2 increases expression ISO tamibarotene results in increased expression of SH2B2 mRNA CTD PMID:17229644 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844
JBrowse link
G Sh2d1a SH2 domain containing 1A decreases expression ISO tamibarotene results in decreased expression of SH2D1A mRNA CTD PMID:17229644 NCBI chr  X:121,373,693...121,401,923 JBrowse link
G Sipa1 signal-induced proliferation-associated 1 increases expression ISO tamibarotene results in increased expression of SIPA1 mRNA CTD PMID:15498508 NCBI chr 1:202,938,532...202,950,672
Ensembl chr 1:202,938,580...202,950,591
JBrowse link
G Skp2 S-phase kinase associated protein 2 decreases expression ISO tamibarotene results in decreased expression of SKP2 mRNA CTD PMID:15498508 NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
JBrowse link
G Sla src-like adaptor increases expression ISO tamibarotene results in increased expression of SLA mRNA CTD PMID:15498508 NCBI chr 7:98,534,431...98,584,810
Ensembl chr 7:98,535,368...98,584,648
JBrowse link
G Slc16a1 solute carrier family 16 member 1 affects expression ISO tamibarotene affects the expression of SLC16A1 mRNA CTD PMID:15498508 NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611
JBrowse link
G Slc16a3 solute carrier family 16 member 3 increases expression ISO tamibarotene results in increased expression of SLC16A3 mRNA CTD PMID:15498508 NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562
JBrowse link
G Slc16a7 solute carrier family 16 member 7 affects expression ISO tamibarotene affects the expression of SLC16A7 mRNA CTD PMID:15498508 NCBI chr 7:61,043,667...61,211,547
Ensembl chr 7:61,051,167...61,154,994
JBrowse link
G Slc18a3 solute carrier family 18 member A3 increases expression ISO tamibarotene results in increased expression of SLC18A3 mRNA CTD PMID:20138974 NCBI chr16:7,713,630...7,716,491 JBrowse link
G Slc1a1 solute carrier family 1 member 1 increases activity
multiple interactions
increases expression
EXP tamibarotene results in increased activity of SLC1A1 protein
HX 630 promotes the reaction [tamibarotene results in increased activity of SLC1A1 protein]; HX 630 promotes the reaction [tamibarotene results in increased expression of SLC1A1 protein]
CTD PMID:19450544 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402
JBrowse link
G Slc1a6 solute carrier family 1 member 6 decreases expression ISO tamibarotene results in decreased expression of SLC1A6 mRNA CTD PMID:15498508 NCBI chr 7:10,841,836...10,870,424
Ensembl chr 7:10,841,837...10,870,449
JBrowse link
G Slc26a2 solute carrier family 26 member 2 affects expression ISO tamibarotene affects the expression of SLC26A2 mRNA CTD PMID:15498508 NCBI chr18:54,648,276...54,666,627
Ensembl chr18:54,652,951...54,666,626
JBrowse link
G Slc2a4rg SLC2A4 regulator increases expression ISO tamibarotene results in increased expression of SLC2A4RG mRNA CTD PMID:17229644 NCBI chr 3:168,493,975...168,497,616 JBrowse link
G Slc2a5 solute carrier family 2 member 5 increases expression ISO tamibarotene results in increased expression of SLC2A5 mRNA CTD PMID:15498508 NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
JBrowse link
G Slc36a1 solute carrier family 36 member 1 increases expression ISO tamibarotene results in increased expression of SLC36A1 mRNA CTD PMID:15498508 NCBI chr10:39,319,062...39,357,374
Ensembl chr10:39,324,337...39,354,217
JBrowse link
G Slc4a7 solute carrier family 4 member 7 affects expression ISO tamibarotene affects the expression of SLC4A7 mRNA CTD PMID:15498508 NCBI chr15:10,585,307...10,664,780
Ensembl chr15:10,588,979...10,664,781
JBrowse link
G Smad2 SMAD family member 2 decreases expression
increases phosphorylation
ISO tamibarotene results in decreased expression of SMAD2 mRNA
tamibarotene results in increased phosphorylation of SMAD2 protein
CTD PMID:15498508 PMID:17611697 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad4 SMAD family member 4 decreases expression ISO tamibarotene results in decreased expression of SMAD4 mRNA CTD PMID:15498508 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438
JBrowse link
G Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 affects expression ISO tamibarotene affects the expression of SMARCC1 mRNA CTD PMID:15498508 NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO tamibarotene results in decreased expression of SMC4 mRNA CTD PMID:15498508 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Smc5 structural maintenance of chromosomes 5 affects expression ISO tamibarotene affects the expression of SMC5 mRNA CTD PMID:15498508 NCBI chr 1:220,769,366...220,839,138
Ensembl chr 1:220,769,366...220,839,096
JBrowse link
G Smox spermine oxidase increases expression ISO tamibarotene results in increased expression of SMOX mRNA CTD PMID:15498508 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
G Smpd1 sphingomyelin phosphodiesterase 1 increases expression ISO tamibarotene results in increased expression of SMPD1 mRNA CTD PMID:15498508 NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 decreases expression ISO tamibarotene results in decreased expression of SNRNP200 mRNA CTD PMID:15498508 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182
JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO tamibarotene results in decreased expression of SOD3 mRNA CTD PMID:15498508 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Son SON DNA and RNA binding protein affects expression ISO tamibarotene affects the expression of SON mRNA CTD PMID:15498508 NCBI chr11:30,850,890...30,923,167
Ensembl chr11:30,892,005...30,923,167
JBrowse link
G Spink2 serine peptidase inhibitor, Kazal type 2 decreases expression ISO tamibarotene results in decreased expression of SPINK2 mRNA CTD PMID:15498508 NCBI chr14:30,967,682...30,974,326
Ensembl chr14:30,967,714...30,974,326
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO tamibarotene results in increased expression of SPP1 mRNA CTD PMID:15498508 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Sprr2d small proline-rich protein 2D affects expression ISO tamibarotene affects the expression of SPRR2D mRNA CTD PMID:15498508 NCBI chr 2:177,870,082...177,870,679
Ensembl chr 2:177,870,434...177,870,679
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 increases expression ISO tamibarotene results in increased expression of SPRY2 mRNA CTD PMID:15498508 NCBI chr15:82,692,291...82,697,408
Ensembl chr15:82,692,143...82,698,009
JBrowse link
G Sri sorcin increases expression
affects expression
ISO tamibarotene results in increased expression of SRI mRNA
tamibarotene affects the expression of SRI mRNA
CTD PMID:15498508 PMID:17229644 NCBI chr 4:25,973,493...25,997,879
Ensembl chr 4:25,966,750...25,998,077
JBrowse link
G Srsf10 serine and arginine rich splicing factor 10 affects expression
decreases expression
ISO tamibarotene affects the expression of SRSF10 mRNA
tamibarotene results in decreased expression of SRSF10 mRNA
CTD PMID:15498508 NCBI chr 5:148,088,759...148,102,964
Ensembl chr 5:148,088,823...148,101,768
JBrowse link
G Srsf3 serine and arginine rich splicing factor 3 affects expression ISO tamibarotene affects the expression of SRSF3 mRNA CTD PMID:15498508 NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078
JBrowse link
G Ss18 SS18 subunit of BAF chromatin remodeling complex decreases expression ISO tamibarotene results in decreased expression of SS18 mRNA CTD PMID:15498508 NCBI chr18:5,773,042...5,835,696
Ensembl chr18:5,773,042...5,835,333
JBrowse link
G Ssr1 signal sequence receptor subunit 1 affects expression ISO tamibarotene affects the expression of SSR1 mRNA CTD PMID:15498508 NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO tamibarotene results in increased expression of STAT1 mRNA CTD PMID:15498508 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Stat5b signal transducer and activator of transcription 5B decreases expression ISO tamibarotene results in decreased expression of STAT5B mRNA CTD PMID:15498508 NCBI chr10:85,704,841...85,775,856
Ensembl chr10:85,705,670...85,775,668
JBrowse link
G Stx16 syntaxin 16 affects expression ISO tamibarotene affects the expression of STX16 mRNA CTD PMID:15498508 NCBI chr 3:162,853,764...162,882,489
Ensembl chr 3:162,853,782...162,882,489
JBrowse link
G Stx1a syntaxin 1A decreases expression ISO tamibarotene results in decreased expression of STX1A mRNA CTD PMID:15498508 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930
JBrowse link
G Surf1 SURF1, cytochrome c oxidase assembly factor affects expression ISO tamibarotene affects the expression of SURF1 mRNA CTD PMID:15498508 NCBI chr 3:10,241,793...10,244,686
Ensembl chr 3:10,241,837...10,263,315
JBrowse link
G Sympk symplekin scaffold protein affects expression ISO tamibarotene affects the expression of SYMPK mRNA CTD PMID:15498508 NCBI chr 1:78,672,372...78,700,684
Ensembl chr 1:78,672,378...78,700,684
JBrowse link
G Szrd1 SUZ RNA binding domain containing 1 decreases expression ISO tamibarotene results in decreased expression of SZRD1 mRNA CTD PMID:15498508 NCBI chr 5:153,418,748...153,443,286
Ensembl chr 5:153,418,748...153,443,252
JBrowse link
G Taf10 TATA-box binding protein associated factor 10 increases expression ISO tamibarotene results in increased expression of TAF10 mRNA CTD PMID:15498508 NCBI chr 1:160,095,108...160,096,401
Ensembl chr 1:160,095,108...160,096,376
JBrowse link
G Taf15 TATA-box binding protein associated factor 15 decreases expression ISO tamibarotene results in decreased expression of TAF15 mRNA CTD PMID:15498508 NCBI chr10:68,272,921...68,304,951
Ensembl chr10:68,272,969...68,304,949
JBrowse link
G Tagln transgelin affects expression ISO tamibarotene affects the expression of TAGLN mRNA CTD PMID:15498508 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO tamibarotene results in increased expression of TAP1 mRNA CTD PMID:15498508 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member increases expression ISO tamibarotene results in increased expression of TAP2 mRNA CTD PMID:15498508 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
G Tbc1d5 TBC1 domain family, member 5 decreases expression ISO tamibarotene results in decreased expression of TBC1D5 mRNA CTD PMID:15498508 NCBI chr 9:3,503,328...4,017,131
Ensembl chr 9:3,513,623...4,016,913
JBrowse link
G Tbkbp1 TBK1 binding protein 1 decreases expression ISO tamibarotene results in decreased expression of TBKBP1 mRNA CTD PMID:15498508 NCBI chr10:82,120,558...82,135,749
Ensembl chr10:82,120,564...82,134,352
JBrowse link
G Tcirg1 T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3 increases expression ISO tamibarotene results in increased expression of TCIRG1 mRNA CTD PMID:15498508 NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742
JBrowse link
G Tdrd3 tudor domain containing 3 decreases expression ISO tamibarotene results in decreased expression of TDRD3 mRNA CTD PMID:15498508 NCBI chr15:63,340,531...63,497,208
Ensembl chr15:63,341,235...63,476,110
JBrowse link
G Tfdp1 transcription factor Dp-1 affects expression ISO tamibarotene affects the expression of TFDP1 mRNA CTD PMID:15498508 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817
JBrowse link
G Tfdp2 transcription factor Dp-2 decreases expression ISO tamibarotene results in decreased expression of TFDP2 mRNA CTD PMID:15498508 NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682
JBrowse link
G Tfeb transcription factor EB increases expression ISO tamibarotene results in increased expression of TFEB mRNA CTD PMID:17229644 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
ISO tamibarotene results in decreased expression of TGFB1 mRNA
IL17A affects the reaction [tamibarotene results in decreased expression of TGFB1 mRNA]
CTD PMID:22077062 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb2 transforming growth factor, beta 2 increases secretion
increases response to substance
ISO tamibarotene results in increased secretion of TGFB2 protein
TGFB2 results in increased susceptibility to tamibarotene
CTD PMID:17611697 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 decreases expression ISO tamibarotene results in decreased expression of TGIF1 mRNA CTD PMID:15498508 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802
JBrowse link
G Tgm2 transglutaminase 2 increases activity ISO tamibarotene results in increased activity of TGM2 protein CTD PMID:2884032 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Tgm5 transglutaminase 5 increases expression ISO tamibarotene results in increased expression of TGM5 mRNA CTD PMID:15498508 NCBI chr 3:108,008,087...108,044,013
Ensembl chr 3:108,008,143...108,043,976
JBrowse link
G Tgoln2 trans-golgi network protein 2 affects expression ISO tamibarotene affects the expression of TGOLN2 mRNA CTD PMID:15498508 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164
JBrowse link
G Thbd thrombomodulin multiple interactions
increases expression
ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of THBD mRNA]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [tamibarotene results in increased expression of THBD mRNA] CTD PMID:15020266 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193
JBrowse link
G Themis2 thymocyte selection associated family member 2 increases expression ISO tamibarotene results in increased expression of THEMIS2 mRNA CTD PMID:15498508 NCBI chr 5:144,991,110...145,006,362
Ensembl chr 5:144,991,112...145,006,400
JBrowse link
G Timm17a translocase of inner mitochondrial membrane 17A affects expression ISO tamibarotene affects the expression of TIMM17A mRNA CTD PMID:15498508 NCBI chr13:46,731,117...46,742,604
Ensembl chr13:46,730,660...46,742,655
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO tamibarotene results in increased expression of TIMP1 mRNA CTD PMID:15498508 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tm9sf4 transmembrane 9 superfamily member 4 decreases expression ISO tamibarotene results in decreased expression of TM9SF4 mRNA CTD PMID:15498508 NCBI chr 3:141,627,128...141,675,386
Ensembl chr 3:141,627,346...141,675,386
JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 affects expression ISO tamibarotene affects the expression of TMBIM6 mRNA CTD PMID:15498508 NCBI chr 7:130,527,313...130,542,567
Ensembl chr 7:130,527,316...130,543,633
JBrowse link
G Tmc6 transmembrane channel like 6 increases expression ISO tamibarotene results in increased expression of TMC6 mRNA CTD PMID:15498508 NCBI chr10:102,982,059...102,999,509
Ensembl chr10:102,971,229...102,998,960
JBrowse link
G Tmpo thymopoietin affects expression ISO tamibarotene affects the expression of TMPO mRNA CTD PMID:15498508 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases activity
increases expression
multiple interactions
EXP
ISO
tamibarotene results in decreased expression of TNF mRNA
tamibarotene results in increased activity of TNF protein
tamibarotene results in increased expression of TNF mRNA
tamibarotene inhibits the reaction [MBP results in increased expression of TNF mRNA]
CTD PMID:11043609 PMID:11501064 PMID:15498508 PMID:15703382 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfaip2 TNF alpha induced protein 2 increases expression ISO tamibarotene results in increased expression of TNFAIP2 mRNA CTD PMID:15498508 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO tamibarotene results in increased expression of TNFRSF14 mRNA CTD PMID:15498508 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703
JBrowse link
G Tnfrsf17 TNF receptor superfamily member 17 increases expression ISO tamibarotene results in increased expression of TNFRSF17 mRNA CTD PMID:17229644 NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression
increases activity
ISO tamibarotene results in increased expression of TNFSF10 mRNA
tamibarotene results in increased activity of TNFSF10 protein
CTD PMID:15498508 PMID:15703382 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tnfsf14 TNF superfamily member 14 increases expression ISO tamibarotene results in increased expression of TNFSF14 mRNA CTD PMID:15498508 NCBI chr 9:2,068,295...2,073,128
Ensembl chr 9:2,069,104...2,073,216
JBrowse link
G Tnpo1 transportin 1 decreases expression ISO tamibarotene results in decreased expression of TNPO1 mRNA CTD PMID:15498508 NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375
JBrowse link
G Top1 DNA topoisomerase I decreases expression ISO tamibarotene results in decreased expression of TOP1 mRNA CTD PMID:15498508 NCBI chr 3:149,293,469...149,376,618
Ensembl chr 3:149,293,403...149,376,623
JBrowse link
G Top2a DNA topoisomerase II alpha affects expression ISO tamibarotene affects the expression of TOP2A mRNA CTD PMID:15498508 NCBI chr10:83,945,731...83,976,874
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Top2b DNA topoisomerase II beta affects expression ISO tamibarotene affects the expression of TOP2B mRNA CTD PMID:15498508 NCBI chr15:9,051,340...9,111,721
Ensembl chr15:9,051,341...9,112,085
JBrowse link
G Tor1b torsin family 1, member B increases expression ISO tamibarotene results in increased expression of TOR1B mRNA CTD PMID:15498508 NCBI chr 3:14,243,181...14,249,279
Ensembl chr 3:14,243,243...14,249,272
JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression ISO tamibarotene results in decreased expression of TPR mRNA CTD PMID:15498508 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
JBrowse link
G Traf5 TNF receptor-associated factor 5 decreases expression ISO tamibarotene results in decreased expression of TRAF5 mRNA CTD PMID:17229644 NCBI chr13:103,569,944...103,618,747
Ensembl chr13:103,572,314...103,618,709
JBrowse link
G Trib1 tribbles pseudokinase 1 affects expression ISO tamibarotene affects the expression of TRIB1 mRNA CTD PMID:15498508 NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731
JBrowse link
G Trim25 tripartite motif-containing 25 affects expression ISO tamibarotene affects the expression of TRIM25 mRNA CTD PMID:15498508 NCBI chr10:73,812,818...73,831,271
Ensembl chr10:73,812,818...73,831,257
JBrowse link
G Trim33 tripartite motif-containing 33 decreases expression ISO tamibarotene results in decreased expression of TRIM33 mRNA CTD PMID:15498508 NCBI chr 2:190,812,329...190,892,663
Ensembl chr 2:190,807,243...190,888,814
JBrowse link
G Trio trio Rho guanine nucleotide exchange factor affects expression ISO tamibarotene affects the expression of TRIO mRNA CTD PMID:15498508 NCBI chr 2:78,505,069...78,801,384
Ensembl chr 2:78,505,070...78,803,135
JBrowse link
G Troap trophinin associated protein decreases expression ISO tamibarotene results in decreased expression of TROAP mRNA CTD PMID:15498508 NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365
JBrowse link
G Trrap transformation/transcription domain-associated protein decreases expression ISO tamibarotene results in decreased expression of TRRAP mRNA CTD PMID:15498508 NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674
JBrowse link
G Tspyl4 TSPY-like 4 decreases expression ISO tamibarotene results in decreased expression of TSPYL4 mRNA CTD PMID:15498508 NCBI chr20:38,098,756...38,100,752
Ensembl chr20:38,098,677...38,103,053
JBrowse link
G Ttc3 tetratricopeptide repeat domain 3 decreases expression ISO tamibarotene results in decreased expression of TTC3 mRNA CTD PMID:15498508 NCBI chr11:33,689,119...33,788,976
Ensembl chr11:33,688,952...33,788,975
JBrowse link
G Ttr transthyretin increases expression ISO tamibarotene results in increased expression of TTR mRNA CTD PMID:20138974 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008
JBrowse link
G Tuba4a tubulin, alpha 4A affects expression ISO tamibarotene affects the expression of TUBA4A mRNA CTD PMID:15498508 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
JBrowse link
G Tubb2b tubulin, beta 2B class IIb increases expression ISO tamibarotene results in increased expression of TUBB2B mRNA CTD PMID:15498508 NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
JBrowse link
G Tubb3 tubulin, beta 3 class III increases expression EXP tamibarotene results in increased expression of TUBB3 CTD PMID:19182380 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Tulp3 TUB like protein 3 affects expression ISO tamibarotene affects the expression of TULP3 mRNA CTD PMID:15498508 NCBI chr 4:161,590,478...161,632,244
Ensembl chr 4:161,590,479...161,632,149
JBrowse link
G Twf2 twinfilin actin-binding protein 2 affects expression ISO tamibarotene affects the expression of TWF2 mRNA CTD PMID:15498508 NCBI chr 8:106,845,253...106,858,298
Ensembl chr 8:106,845,253...106,858,298
JBrowse link
G Tyro3 TYRO3 protein tyrosine kinase decreases expression ISO tamibarotene results in decreased expression of TYRO3 mRNA CTD PMID:15498508 NCBI chr 3:106,777,686...106,797,154
Ensembl chr 3:106,777,635...106,797,142
JBrowse link
G Tyrobp transmembrane immune signaling adaptor Tyrobp increases expression ISO tamibarotene results in increased expression of TYROBP mRNA CTD PMID:15498508 NCBI chr 1:85,672,931...85,676,856
Ensembl chr 1:85,672,994...85,676,848
JBrowse link
G Uba7 ubiquitin-like modifier activating enzyme 7 increases expression ISO tamibarotene results in increased expression of UBA7 mRNA CTD PMID:15498508 NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:108,665,292...108,674,099
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase affects expression ISO tamibarotene affects the expression of UGCG mRNA CTD PMID:15498508 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Uros uroporphyrinogen III synthase affects expression ISO tamibarotene affects the expression of UROS mRNA CTD PMID:15498508 NCBI chr 1:188,490,832...188,513,659
Ensembl chr 1:188,490,323...188,512,249
JBrowse link
G Usp13 ubiquitin specific peptidase 13 decreases expression ISO tamibarotene results in decreased expression of USP13 mRNA CTD PMID:15498508 NCBI chr 2:115,576,912...115,689,153
Ensembl chr 2:115,577,091...115,686,222
JBrowse link
G Usp9x ubiquitin specific peptidase 9, X-linked affects expression ISO tamibarotene affects the expression of USP9X mRNA CTD PMID:15498508 NCBI chr  X:9,588,825...9,726,993
Ensembl chr  X:9,588,825...9,696,711
JBrowse link
G Utp20 UTP20 small subunit processome component decreases expression ISO tamibarotene results in decreased expression of UTP20 mRNA CTD PMID:15498508 NCBI chr 7:23,134,630...23,215,639
Ensembl chr 7:23,134,637...23,215,632
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein increases expression ISO tamibarotene results in increased expression of VASP mRNA CTD PMID:15498508 NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061
JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 increases expression ISO tamibarotene results in increased expression of VAV1 mRNA CTD PMID:17229644 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937
JBrowse link
G Vav3 vav guanine nucleotide exchange factor 3 decreases expression ISO tamibarotene results in decreased expression of VAV3 mRNA CTD PMID:17229644 NCBI chr 2:197,011,901...197,354,321
Ensembl chr 2:197,011,831...197,354,321
JBrowse link
G Vegfa vascular endothelial growth factor A increases secretion
increases expression
ISO tamibarotene results in increased secretion of VEGFA protein
tamibarotene results in increased expression of VEGFA mRNA
CTD PMID:17170094 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vezf1 vascular endothelial zinc finger 1 affects expression ISO tamibarotene affects the expression of VEZF1 mRNA CTD PMID:15498508 NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111
JBrowse link
G Vim vimentin decreases expression ISO tamibarotene results in decreased expression of VIM mRNA CTD PMID:15498508 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Vrk2 VRK serine/threonine kinase 2 affects expression ISO tamibarotene affects the expression of VRK2 mRNA CTD PMID:15498508 NCBI chr14:100,313,771...100,434,520
Ensembl chr14:100,313,601...100,434,527
JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression ISO tamibarotene results in increased expression of WARS1 mRNA CTD PMID:15498508 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase affects expression ISO tamibarotene affects the expression of WEE1 mRNA CTD PMID:15498508 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688
JBrowse link
G Wnk1 WNK lysine deficient protein kinase 1 decreases expression ISO tamibarotene results in decreased expression of WNK1 mRNA CTD PMID:15498508 NCBI chr 4:153,128,334...153,253,905
Ensembl chr 4:153,128,334...153,253,905
JBrowse link
G Xbp1 X-box binding protein 1 increases expression ISO tamibarotene results in increased expression of XBP1 mRNA CTD PMID:17229644 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
JBrowse link
G Xpot exportin for tRNA decreases expression ISO tamibarotene results in decreased expression of XPOT mRNA CTD PMID:15498508 NCBI chr 7:57,111,536...57,152,013
Ensembl chr 7:57,111,536...57,152,099
JBrowse link
G Ykt6 YKT6 v-SNARE homolog affects expression ISO tamibarotene affects the expression of YKT6 mRNA CTD PMID:15498508 NCBI chr14:80,832,187...80,843,394
Ensembl chr14:80,832,187...80,843,385
JBrowse link
G Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta affects expression ISO tamibarotene affects the expression of YWHAZ mRNA CTD PMID:15498508 NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
JBrowse link
G Zbtb16 zinc finger and BTB domain containing 16 decreases expression ISO tamibarotene results in decreased expression of ZBTB16 mRNA CTD PMID:15498508 NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011
JBrowse link
G Zcchc24 zinc finger CCHC-type containing 24 increases expression ISO tamibarotene results in increased expression of ZCCHC24 mRNA CTD PMID:15498508 NCBI chr16:1,274,544...1,326,664
Ensembl chr16:1,274,548...1,326,696
JBrowse link
G Zfp148 zinc finger protein 148 affects expression
decreases expression
ISO tamibarotene affects the expression of ZNF148 mRNA
tamibarotene results in decreased expression of ZNF148 mRNA
CTD PMID:15498508 NCBI chr11:67,276,455...67,385,803
Ensembl chr11:67,281,707...67,385,772
JBrowse link
G Zfp263 zinc finger protein 263 decreases expression ISO tamibarotene results in decreased expression of ZNF263 mRNA CTD PMID:15498508 NCBI chr10:11,764,424...11,774,324
Ensembl chr10:11,764,427...11,771,235
JBrowse link
G Zfp267 zinc finger protein 267 decreases expression ISO tamibarotene results in decreased expression of ZNF267 mRNA CTD PMID:15498508 NCBI chr 2:119,017,280...119,035,885
Ensembl chr 2:119,017,285...119,031,900
JBrowse link
varespladib term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F10 coagulation factor X multiple interactions ISO varespladib inhibits the reaction [micrurus venom results in decreased activity of F10 protein] CTD PMID:33197555 NCBI chr16:76,468,834...76,488,141
Ensembl chr16:76,468,838...76,488,141
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP [Antivenins co-treated with varespladib] inhibits the reaction [micrurus venom results in increased expression of GPT protein] CTD PMID:34774704 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Pla2g2a phospholipase A2 group IIA decreases activity
multiple interactions
EXP
ISO
varespladib results in decreased activity of PLA2G2A protein
varespladib inhibits the reaction [PLA2G2A protein results in increased abundance of Thromboxane A2 metabolite]; varespladib inhibits the reaction [PLA2G2A protein results in increased abundance of Thromboxane B2]
CTD PMID:10027849 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
varespladib methyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP2 mRNA]; varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP2 protein]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP9 protein]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of PLA2G2A protein] CTD PMID:19765281 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP1 mRNA]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP1 protein] CTD PMID:19765281 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions ISO varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP2 mRNA]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP2 protein] CTD PMID:19765281 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP3 mRNA]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein] CTD PMID:19765281 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO varespladib methyl inhibits the reaction [IL1B protein results in increased expression of MMP9 mRNA]; varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of MMP9 protein] CTD PMID:19765281 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Pla2g2a phospholipase A2 group IIA multiple interactions ISO varespladib methyl inhibits the reaction [IL1B protein results in increased secretion of PLA2G2A protein] CTD PMID:19765281 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
ximelagatran term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F2 coagulation factor II, thrombin decreases cleavage
multiple interactions
ISO ximelagatran results in decreased cleavage of F2 protein
ximelagatran binds to and results in decreased activity of F2 protein
CTD PMID:15155122 PMID:16084352 PMID:16194202 PMID:17314111 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19918
    chemical entity 19916
      atom 19916
        nonmetal atom 19852
          nitrogen atom 19013
            nitrogen molecular entity 19013
              organonitrogen compound 18856
                carboxamide 17575
                  dicarboxylic acid amide 3157
                    dicarboxylic acid monoamide 684
                      (Z)-4-glutaramidostilbene 0
                      1-(2-\{4-[(4-carboxybutanoyl)amino]phenyl\}ethyl)-1-methylpiperidinium 0
                      2-hydroxyglutaramic acid 0
                      2-oxosuccinamic acid 0
                      4-(4-styrylphenylcarbamoyl)butyric acid 0
                      4-(5-carboxypentanamido)antipyrine 0
                      4-(\{[(1S,3S,4R)-3-(dimethylcarbamoyl)bicyclo[2.2.2]oct-1-yl]carbamoyloxy\}methyl)benzoic acid 0
                      4-carbamoylbenzoic acid + 573
                      5-(\{4-[2-(1-oxidopiperidin-1-yl)ethyl]phenyl\}amino)-5-oxopentanoic acid 0
                      5-[(2-aminobenzimidazol-6-yl)amino]-5-oxopentanoic acid 0
                      5-[(2-aminobenzimidazol-6-yl)amino]-5-oxopentanoic acid zwitterion 0
                      5-\{[4-(\{hydroxy[(4-nitrophenyl)amino]phosphoryl\}methyl)phenyl]amino\}-5-oxopentanoic acid 0
                      8-benzyl-7-hydroxy-4,10-dioxo-1-phenyl-6-oxa-3,9-diaza-7-phosphatetradecan-14-oic acid 7-oxide 0
                      CGS-21680 39
                      Dnp-Gln 0
                      E64 0
                      EG00229 0
                      L-cysteine glutathione disulfide 0
                      L-cystine mono-2-naphthylamide 0
                      N(2)-(3,4-dichlorobenzoyl)-N,N-dipentyl-alpha-glutamine + 0
                      N(2)-benzoyl-N,N-dipropyl-alpha-glutamine + 0
                      N(2)-phenylacetylglutamine + 0
                      N(3)-fumaroyl-(S)-2,3-diaminopropanoic acid 0
                      N-(2-hydroxyphenyl)malonamic acid 0
                      N-(3,4-dichlorophenyl)malonamic acid 0
                      N-(8-carboxy-3-oxooctanoyl)-L-homoserine lactone 0
                      N-2-fluorenylphthalamic acid 0
                      N-alkylphthalic monoamide 0
                      N-ethylasparagine + 0
                      N-malonylanthranilic acid 0
                      N-succinyl-L-glutamic 5-semialdehyde 0
                      TMC-52A 0
                      TMC-52C 0
                      TMC-52D 0
                      WF14865A 0
                      WF14865B 0
                      adipamic acid + 0
                      asparagine + 79
                      cacibiocin A + 0
                      candoxatrilat + 3
                      carboxyfentanyl 0
                      cathestatin A 0
                      cathestatin B 0
                      coprine 0
                      fumimycin 0
                      gamma-glutamyltyramine 0
                      glutaramic acid + 0
                      glutathione amide 0
                      homoplatensimide A + 0
                      iooxitalamic acid 1
                      maleamic acid 0
                      mannopine 0
                      melagatran + 1
                      naptalam 0
                      oxamic acid + 1
                      phenyl [1-(N-succinylamino)pentyl]phosphonate 0
                      phthalylsulfathiazole 0
                      succinamic acid + 0
                      tamibarotene 573
                      tecloftalam 0
                      varespladib + 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19918
    subatomic particle 19916
      composite particle 19916
        hadron 19916
          baryon 19916
            nucleon 19916
              atomic nucleus 19916
                atom 19916
                  main group element atom 19866
                    p-block element atom 19866
                      carbon group element atom 19811
                        carbon atom 19806
                          organic molecular entity 19806
                            organic group 18995
                              organic divalent group 18969
                                organodiyl group 18969
                                  carbonyl group 18922
                                    carbonyl compound 18922
                                      carboxylic acid 18646
                                        carboacyl group 17727
                                          univalent carboacyl group 17727
                                            carbamoyl group 17575
                                              carboxamide 17575
                                                dicarboxylic acid amide 3157
                                                  dicarboxylic acid monoamide 684
                                                    (Z)-4-glutaramidostilbene 0
                                                    1-(2-\{4-[(4-carboxybutanoyl)amino]phenyl\}ethyl)-1-methylpiperidinium 0
                                                    2-hydroxyglutaramic acid 0
                                                    2-oxosuccinamic acid 0
                                                    4-(4-styrylphenylcarbamoyl)butyric acid 0
                                                    4-(5-carboxypentanamido)antipyrine 0
                                                    4-(\{[(1S,3S,4R)-3-(dimethylcarbamoyl)bicyclo[2.2.2]oct-1-yl]carbamoyloxy\}methyl)benzoic acid 0
                                                    4-carbamoylbenzoic acid + 573
                                                    5-(\{4-[2-(1-oxidopiperidin-1-yl)ethyl]phenyl\}amino)-5-oxopentanoic acid 0
                                                    5-[(2-aminobenzimidazol-6-yl)amino]-5-oxopentanoic acid 0
                                                    5-[(2-aminobenzimidazol-6-yl)amino]-5-oxopentanoic acid zwitterion 0
                                                    5-\{[4-(\{hydroxy[(4-nitrophenyl)amino]phosphoryl\}methyl)phenyl]amino\}-5-oxopentanoic acid 0
                                                    8-benzyl-7-hydroxy-4,10-dioxo-1-phenyl-6-oxa-3,9-diaza-7-phosphatetradecan-14-oic acid 7-oxide 0
                                                    CGS-21680 39
                                                    Dnp-Gln 0
                                                    E64 0
                                                    EG00229 0
                                                    L-cysteine glutathione disulfide 0
                                                    L-cystine mono-2-naphthylamide 0
                                                    N(2)-(3,4-dichlorobenzoyl)-N,N-dipentyl-alpha-glutamine + 0
                                                    N(2)-benzoyl-N,N-dipropyl-alpha-glutamine + 0
                                                    N(2)-phenylacetylglutamine + 0
                                                    N(3)-fumaroyl-(S)-2,3-diaminopropanoic acid 0
                                                    N-(2-hydroxyphenyl)malonamic acid 0
                                                    N-(3,4-dichlorophenyl)malonamic acid 0
                                                    N-(8-carboxy-3-oxooctanoyl)-L-homoserine lactone 0
                                                    N-2-fluorenylphthalamic acid 0
                                                    N-alkylphthalic monoamide 0
                                                    N-ethylasparagine + 0
                                                    N-malonylanthranilic acid 0
                                                    N-succinyl-L-glutamic 5-semialdehyde 0
                                                    TMC-52A 0
                                                    TMC-52C 0
                                                    TMC-52D 0
                                                    WF14865A 0
                                                    WF14865B 0
                                                    adipamic acid + 0
                                                    asparagine + 79
                                                    cacibiocin A + 0
                                                    candoxatrilat + 3
                                                    carboxyfentanyl 0
                                                    cathestatin A 0
                                                    cathestatin B 0
                                                    coprine 0
                                                    fumimycin 0
                                                    gamma-glutamyltyramine 0
                                                    glutaramic acid + 0
                                                    glutathione amide 0
                                                    homoplatensimide A + 0
                                                    iooxitalamic acid 1
                                                    maleamic acid 0
                                                    mannopine 0
                                                    melagatran + 1
                                                    naptalam 0
                                                    oxamic acid + 1
                                                    phenyl [1-(N-succinylamino)pentyl]phosphonate 0
                                                    phthalylsulfathiazole 0
                                                    succinamic acid + 0
                                                    tamibarotene 573
                                                    tecloftalam 0
                                                    varespladib + 8
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