lanthanoid coordination entity - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	lanthanoid coordination entity	go back to main search page
Accession:	CHEBI:35728	browse the term
Synonyms:	related_synonym:	lanthanoid coordination compounds; lanthanoid coordination entities

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Rat (454) Mouse (463) Human (467) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (454)

cerium trichloride

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

abhydrolase domain containing 14b

increases expression

cerous chloride results in increased expression of ABHD14B mRNA

NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119

G

acetyl-CoA acyltransferase 1A

increases expression

cerous chloride results in increased expression of ACAA1A mRNA

NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624

G

adenylate cyclase 8

decreases expression

cerous chloride results in decreased expression of ADCY8 mRNA

NCBI chr 7:96,417,310...96,665,911
Ensembl chr 7:96,417,324...96,665,911

G

adhesion G protein-coupled receptor B3

increases expression

cerous chloride results in increased expression of ADGRB3 mRNA

NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855

G

adenosine A2B receptor

decreases expression

cerous chloride results in decreased expression of ADORA2B mRNA

NCBI chr10:46,940,394...46,956,772
Ensembl chr10:46,940,384...46,956,772

G

argonaute RISC catalytic component 2

increases expression

cerous chloride results in increased expression of AGO2 mRNA

NCBI chr 7:105,018,202...105,105,118
Ensembl chr 7:105,029,120...105,104,974

G

1-acylglycerol-3-phosphate O-acyltransferase 1

decreases expression

cerous chloride results in decreased expression of AGPAT1 mRNA

NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278

G

A-kinase anchoring protein 17A

increases expression

cerous chloride results in increased expression of AKAP17B mRNA

NCBI chr12:16,310,427...16,315,166
Ensembl chr12:16,310,437...16,314,479

G

albumin

affects expression

cerous chloride affects the expression of ALB mRNA

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

arachidonate 12-lipoxygenase, 12S type

decreases expression
multiple interactions

cerous chloride results in decreased expression of ALOX12 mRNA
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of ALOX12 mRNA

NCBI chr10:54,958,263...54,970,542
Ensembl chr10:54,958,271...54,970,542

G

acidic nuclear phosphoprotein 32 family member E

increases expression

cerous chloride results in increased expression of ANP32E mRNA

NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054

G

aldehyde oxidase 1

multiple interactions

[cerous chloride co-treated with lanthanum chloride] results in increased expression of AOX1 mRNA

NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770

G

apolipoprotein A2

increases expression

cerous chloride results in increased expression of APOA2 mRNA

NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355

G

apolipoprotein A4

affects expression

cerous chloride affects the expression of APOA4 mRNA

NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469

G

apolipoprotein E

affects expression
multiple interactions

cerous chloride affects the expression of APOE mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of APOE mRNA

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

activity-regulated cytoskeleton-associated protein

decreases expression

cerous chloride results in decreased expression of ARC mRNA

NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378

G

Rho guanine nucleotide exchange factor 15

increases expression

cerous chloride results in increased expression of ARHGEF15 mRNA

NCBI chr10:53,650,521...53,663,269
Ensembl chr10:53,650,553...53,663,913

G

Rho/Rac guanine nucleotide exchange factor 2

increases expression

cerous chloride results in increased expression of LBCL1 mRNA

NCBI chr 2:174,061,126...174,118,355
Ensembl chr 2:174,062,976...174,118,355

G

beta-2 microglobulin

increases expression

cerous chloride results in increased expression of B2M mRNA

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

G

BCL9, transcription coactivator

increases expression

cerous chloride results in increased expression of BCL9 mRNA

NCBI chr 2:184,760,616...184,846,261
Ensembl chr 2:184,760,618...184,786,435

G

BCL2-associated transcription factor 1

increases expression

cerous chloride results in increased expression of BCLAF1 mRNA

NCBI chr 1:15,088,436...15,117,666
Ensembl chr 1:15,070,894...15,148,832

G

calmodulin 2

increases expression

cerous chloride results in increased expression of CALM2 mRNA

NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287

G

cathelicidin antimicrobial peptide

increases expression

cerous chloride results in increased expression of CAMP mRNA

NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543

G

catalase

multiple interactions
decreases expression

[cerous chloride co-treated with lanthanum chloride] results in decreased expression of CAT mRNA
cerous chloride results in decreased expression of CAT mRNA

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

C-C motif chemokine ligand 5

increases expression
multiple interactions

cerous chloride results in increased expression of CCL5 mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of CCL5 mRNA

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cyclin T2

increases expression

cerous chloride results in increased expression of CCNT2 mRNA

NCBI chr13:39,251,573...39,293,172
Ensembl chr13:39,251,573...39,292,019

G

copper chaperone for superoxide dismutase

multiple interactions
decreases expression

[cerous chloride co-treated with lanthanum chloride] affects the expression of CCS mRNA
cerous chloride results in decreased expression of CCS mRNA

NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915

G

cell division cycle 37, HSP90 cochaperone

increases expression

cerous chloride results in increased expression of CDC37 mRNA

NCBI chr 8:19,677,400...19,690,761
Ensembl chr 8:19,671,938...19,690,809

G

cyclin-dependent kinase inhibitor 1A

decreases expression

cerous chloride results in decreased expression of CDKN1A mRNA

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

carboxyl ester lipase

increases expression

cerous chloride results in increased expression of CEL mRNA

NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035

G

CUGBP, Elav-like family member 2

increases expression

cerous chloride results in increased expression of CELF2 mRNA

NCBI chr17:70,904,462...71,729,072
Ensembl chr17:71,210,853...71,728,333

G

centrosomal protein 63

decreases expression

cerous chloride results in decreased expression of CEP63 mRNA

NCBI chr 8:103,162,639...103,214,177
Ensembl chr 8:103,162,700...103,214,177

G

complement factor D

affects expression

cerous chloride affects the expression of CFD mRNA

NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053

G

complement factor properdin

increases expression

cerous chloride results in increased expression of CFP mRNA

NCBI chr X:1,162,014...1,167,576
Ensembl chr X:1,161,979...1,167,573

G

charged multivesicular body protein 5

decreases expression

cerous chloride results in decreased expression of CHMP5 mRNA

NCBI chr 5:56,081,385...56,098,529
Ensembl chr 5:56,081,343...56,098,529

G

chordin

increases expression

cerous chloride results in increased expression of CHRD mRNA

NCBI chr11:80,171,994...80,181,166
Ensembl chr11:80,171,994...80,180,673

G

component of inhibitor of nuclear factor kappa B kinase complex

increases expression

cerous chloride results in increased expression of CHUK mRNA; cerous chloride results in increased expression of CHUK protein

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

cytoplasmic linker associated protein 2

increases expression

cerous chloride results in increased expression of CLASP2 mRNA

NCBI chr 8:113,677,345...113,859,957
Ensembl chr 8:113,677,284...113,858,731

G

CCR4-NOT transcription complex, subunit 3

increases expression

cerous chloride results in increased expression of CNOT3 mRNA

NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167

G

chondroitin sulfate proteoglycan 5

increases expression

cerous chloride results in increased expression of CSPG5 mRNA

NCBI chr 8:110,220,506...110,234,766
Ensembl chr 8:110,220,653...110,234,758

G

cysteine and serine rich nuclear protein 1

increases expression

cerous chloride results in increased expression of AXUD1 mRNA

NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183

G

cortactin binding protein 2

increases expression

cerous chloride results in increased expression of CTTNBP2 mRNA

NCBI chr 4:46,800,975...46,964,681
Ensembl chr 4:46,800,981...46,964,631

G

cullin 1

increases expression

cerous chloride results in increased expression of CUL1 mRNA

NCBI chr 4:76,551,952...76,625,830
Ensembl chr 4:76,551,983...76,627,980

G

cytoglobin

affects expression
multiple interactions

cerous chloride affects the expression of CYGB mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of CYGB mRNA

NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442

G

cytochrome P450, family 1, subfamily a, polypeptide 1

increases expression

cerous chloride results in increased expression of CYP1A1

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 46, subfamily a, polypeptide 1

increases expression

cerous chloride results in increased expression of CYP46A1 mRNA

NCBI chr 6:127,247,543...127,274,765
Ensembl chr 6:127,243,315...127,274,760

G

cytochrome P450, family 51

affects expression

cerous chloride affects the expression of CYP51 mRNA

NCBI chr 4:30,036,956...30,055,410
Ensembl chr 4:30,036,865...30,055,410

G

cytochrome P450 family 7 subfamily B member 1

increases expression

cerous chloride results in increased expression of CYP7B1 mRNA

NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698

G

cytochrome P450 family 8 subfamily B member 1

affects expression

cerous chloride affects the expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

doublecortin-like kinase 1

increases expression

cerous chloride results in increased expression of DCLK1 mRNA

NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956

G

diacylglycerol kinase, gamma

increases expression

cerous chloride results in increased expression of DGKG mRNA

NCBI chr11:78,384,212...78,579,158
Ensembl chr11:78,384,458...78,577,212

G

24-dehydrocholesterol reductase

decreases expression

cerous chloride results in decreased expression of DHCR24 mRNA

NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137

G

7-dehydrocholesterol reductase

affects expression

cerous chloride affects the expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

dihydrolipoamide S-succinyltransferase

increases expression

cerous chloride results in increased expression of DLST mRNA

NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296

G

DnaJ heat shock protein family (Hsp40) member C7

increases expression

cerous chloride results in increased expression of DNAJC7 mRNA

NCBI chr10:85,518,637...85,555,079
Ensembl chr10:85,518,621...85,555,575

G

dedicator of cytokinesis 10

increases expression

cerous chloride results in increased expression of DOCK10 mRNA

NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525

G

DOT1 like histone lysine methyltransferase

increases expression

cerous chloride results in increased expression of DOT1L mRNA

NCBI chr 7:8,918,764...8,959,474
Ensembl chr 7:8,917,786...8,956,475

G

dipeptidylpeptidase 8

increases expression

cerous chloride results in increased expression of DPP8 mRNA

NCBI chr 8:65,550,620...65,605,828
Ensembl chr 8:65,550,677...65,605,825

G

dual oxidase 1

decreases expression
multiple interactions

cerous chloride results in decreased expression of DUOX1 mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX1 mRNA

NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563

G

dual oxidase 2

multiple interactions

[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUOX2 mRNA

NCBI chr 3:109,223,809...109,247,023
Ensembl chr 3:109,226,924...109,245,902

G

dihydrouridine synthase 1-like

decreases expression

cerous chloride results in decreased expression of DUS1L mRNA

NCBI chr10:106,055,519...106,062,656
Ensembl chr10:106,055,519...106,062,781

G

dual specificity phosphatase 1

multiple interactions
affects expression

[cerous chloride co-treated with lanthanum chloride] results in increased expression of DUSP1 mRNA
cerous chloride affects the expression of DUSP1 mRNA

NCBI chr10:16,680,478...16,683,275

G

EBP, cholestenol delta-isomerase

affects expression

cerous chloride affects the expression of EBP mRNA

NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826

G

EEF1A lysine methyltransferase 1

decreases expression

cerous chloride results in decreased expression of EEF1AKMT1 mRNA

NCBI chr15:31,694,284...31,711,367
Ensembl chr15:31,694,292...31,711,336

G

early growth response 2

decreases expression

cerous chloride results in decreased expression of EGR2 mRNA

NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562

G

enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase

affects expression

cerous chloride affects the expression of EHHADH mRNA

NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188

G

eukaryotic translation initiation factor 1B

increases expression

cerous chloride results in increased expression of EIF1B mRNA

NCBI chr 8:120,203,561...120,206,176
Ensembl chr 8:120,203,451...120,206,176

G

extracellular leucine-rich repeat and fibronectin type III domain containing 2

increases expression

cerous chloride results in increased expression of ELFN2 mRNA

NCBI chr 7:110,220,293...110,272,770
Ensembl chr 7:110,225,919...110,272,433

G

epoxide hydrolase 2

affects expression
multiple interactions

cerous chloride affects the expression of EPHX2 mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of EPHX2 mRNA

NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615

G

eosinophil peroxidase

decreases expression

cerous chloride results in decreased expression of EPX mRNA

NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952

G

Fc receptor-like 2

decreases expression

cerous chloride results in decreased expression of FCRL2 mRNA

NCBI chr 2:172,694,308...172,707,261
Ensembl chr 2:172,694,308...172,707,051

G

Fos proto-oncogene, AP-1 transcription factor subunit

decreases expression

cerous chloride results in decreased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

forkhead box K2

increases expression

cerous chloride results in increased expression of FOXK2 mRNA

NCBI chr10:106,542,643...106,592,569
Ensembl chr10:106,542,566...106,592,563

G

forkhead box M1

multiple interactions
decreases expression

[cerous chloride co-treated with lanthanum chloride] results in decreased expression of FOXM1 mRNA
cerous chloride results in decreased expression of FOXM1 mRNA

NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684

G

formyl peptide receptor 2

increases expression

cerous chloride results in increased expression of FPR2 mRNA

NCBI chr 1:58,776,592...58,785,227
Ensembl chr 1:58,776,752...58,786,019

G

ferritin heavy chain 1

increases expression

cerous chloride results in increased expression of FTH1 mRNA

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

Fus RNA binding protein

increases expression

cerous chloride results in increased expression of FUS mRNA

NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414

G

FMR1 autosomal homolog 2

increases expression

cerous chloride results in increased expression of FXR2 mRNA

NCBI chr10:54,350,577...54,370,964
Ensembl chr10:54,350,131...54,370,964

G

FYVE and coiled-coil domain autophagy adaptor 1

increases expression

cerous chloride results in increased expression of FYCO1 mRNA

NCBI chr 8:123,412,105...123,479,315
Ensembl chr 8:123,412,112...123,479,021

G

glyceraldehyde-3-phosphate dehydrogenase

decreases expression
multiple interactions

cerous chloride results in decreased expression of GAPDH mRNA
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GAPDH mRNA

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

glutamate-cysteine ligase, catalytic subunit

increases expression
multiple interactions

cerous chloride results in increased expression of GCLC mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

decreases expression

cerous chloride results in decreased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

G protein subunit alpha q

increases expression

cerous chloride results in increased expression of GNAQ mRNA

NCBI chr 1:213,425,631...213,671,947
Ensembl chr 1:213,424,465...213,667,672

G

glutamic-oxaloacetic transaminase 1-like 1

decreases expression

cerous chloride results in decreased expression of GOT1L1 mRNA

NCBI chr16:64,860,308...64,873,656
Ensembl chr16:64,860,704...64,866,162

G

glycerol-3-phosphate dehydrogenase 2

affects expression

cerous chloride affects the expression of GPD2 mRNA

NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901

G

gephyrin

increases expression

cerous chloride results in increased expression of GPHN mRNA

NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612

G

glycosylphosphatidylinositol specific phospholipase D1

increases expression

cerous chloride results in increased expression of GPLD1 mRNA

NCBI chr17:40,084,427...40,132,035
Ensembl chr17:40,084,617...40,126,939

G

G protein-coupled receptor 153

increases expression

cerous chloride results in increased expression of GPR153 mRNA

NCBI chr 5:162,781,587...162,792,975
Ensembl chr 5:162,781,587...162,792,971

G

glutathione peroxidase 2

decreases expression

cerous chloride results in decreased expression of GPX2 mRNA

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 3

multiple interactions
affects expression

[cerous chloride co-treated with lanthanum chloride] results in increased expression of GPX3 mRNA
cerous chloride affects the expression of GPX3 mRNA

NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035

G

glutathione peroxidase 4

affects expression

cerous chloride affects the expression of GPX4 mRNA

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

glutathione peroxidase 7

decreases expression
multiple interactions

cerous chloride results in decreased expression of GPX7 mRNA
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of GPX7 mRNA

NCBI chr 5:123,145,151...123,153,141
Ensembl chr 5:123,144,331...123,153,004

G

growth factor receptor bound protein 2

affects expression

cerous chloride affects the expression of GRB2 mRNA

NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309

G

glutathione S-transferase pi 1

decreases expression

cerous chloride results in decreased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase zeta 1

multiple interactions

[cerous chloride co-treated with lanthanum chloride] results in increased expression of GSTZ1 mRNA

NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284

G

general transcription factor II I

decreases expression

cerous chloride results in decreased expression of GTF2I mRNA

NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243

G

Holliday junction recognition protein

increases expression

cerous chloride results in increased expression of HJURP mRNA

NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728

G

heme oxygenase 1

multiple interactions
affects expression

[cerous chloride co-treated with lanthanum chloride] results in decreased expression of HMOX1 mRNA
cerous chloride affects the expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heat shock protein family A (Hsp70) member 1A

decreases expression

cerous chloride results in decreased expression of HSPA1A mRNA

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family E (Hsp10) member 1

decreases expression

cerous chloride results in decreased expression of HSPE1 mRNA

NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089

G

interferon gamma

increases expression

cerous chloride results in increased expression of IFNG

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

inhibitor of nuclear factor kappa B kinase subunit beta

increases expression

cerous chloride results in increased expression of IKBKB mRNA; cerous chloride results in increased expression of IKBKB protein

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

G

interleukin 10

increases expression

cerous chloride results in increased expression of IL10

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 18

increases expression

cerous chloride results in increased expression of IL18

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 beta

increases expression

cerous chloride results in increased expression of IL1B

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

decreases expression
increases expression

cerous chloride results in decreased expression of IL2 mRNA; cerous chloride results in decreased expression of IL2 protein
cerous chloride results in increased expression of IL2

PMID:21656643 PMID:23712967

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 4

increases expression

cerous chloride results in increased expression of IL4

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 6

multiple interactions
increases expression

IL6 mutant form inhibits the reaction [cerous chloride results in increased expression of SAA protein]
cerous chloride results in increased expression of IL6; cerous chloride results in increased expression of IL6 protein

PMID:16204935 PMID:23712967

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

immunoglobulin superfamily containing leucine-rich repeat 2

increases expression

cerous chloride results in increased expression of ISLR2 mRNA

NCBI chr 8:58,608,165...58,616,246
Ensembl chr 8:58,608,709...58,614,650

G

integrin alpha FG-GAP repeat containing 1

increases expression

cerous chloride results in increased expression of ITFG1 mRNA

NCBI chr19:21,210,697...21,331,285
Ensembl chr19:21,210,733...21,331,279

G

Jun proto-oncogene, AP-1 transcription factor subunit

affects expression

cerous chloride affects the expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

lysine acetyltransferase 7

decreases expression

cerous chloride results in decreased expression of MYST2 mRNA

NCBI chr10:80,221,519...80,255,590
Ensembl chr10:80,221,524...80,255,567

G

potassium voltage-gated channel subfamily A member 3

increases expression

cerous chloride results in increased expression of KCNA3 mRNA

NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138

G

potassium inwardly-rectifying channel, subfamily J, member 16

increases expression

cerous chloride results in increased expression of KCNJ16 mRNA

NCBI chr10:95,990,009...96,021,356
Ensembl chr10:95,960,725...96,021,702

G

potassium inwardly-rectifying channel, subfamily J, member 4

increases expression

cerous chloride results in increased expression of KCNJ4 mRNA

NCBI chr 7:111,047,097...111,074,151
Ensembl chr 7:111,047,094...111,074,151

G

potassium voltage-gated channel subfamily Q member 5

increases expression

cerous chloride results in increased expression of KCNQ5 mRNA

NCBI chr 9:23,830,185...24,395,984
Ensembl chr 9:23,833,087...24,394,704

G

kallikrein related-peptidase 6

decreases expression

cerous chloride results in decreased expression of KLK6 mRNA

NCBI chr 1:94,278,863...94,286,136
Ensembl chr 1:94,280,340...94,286,121

G

keratin 12

increases expression

cerous chloride results in increased expression of KRT12 mRNA

NCBI chr10:84,370,803...84,378,103
Ensembl chr10:84,370,883...84,378,045

G

lipocalin 2

increases expression

cerous chloride results in increased expression of LCN2 mRNA

NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095

G

lamin B2

increases expression

cerous chloride results in increased expression of LMNB2 mRNA

NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665

G

lactoperoxidase

multiple interactions
increases expression

[cerous chloride co-treated with lanthanum chloride] results in increased expression of LPO mRNA
cerous chloride results in increased expression of LPO mRNA

NCBI chr10:72,606,950...72,626,220
Ensembl chr10:72,606,944...72,626,535

G

lactotransferrin

increases expression

cerous chloride results in increased expression of LTF mRNA

NCBI chr 8:110,999,948...111,022,795
Ensembl chr 8:110,999,948...111,022,795

G

mal, T-cell differentiation protein

decreases expression

cerous chloride results in decreased expression of MAL mRNA

NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136

G

mitogen-activated protein kinase kinase kinase kinase 4

increases expression

cerous chloride results in increased expression of MAP4K4 mRNA; cerous chloride results in increased expression of MAP4K4 protein

NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698

G

methionine adenosyltransferase 1A

increases expression

cerous chloride results in increased expression of MAT1A mRNA

NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274

G

myoglobin

increases expression
multiple interactions

cerous chloride results in increased expression of MB mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of MB mRNA

NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383

G

mannose binding lectin 2

decreases expression
multiple interactions

cerous chloride results in decreased expression of MBL2 mRNA
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of MBL2 mRNA

NCBI chr 1:228,016,439...228,024,736

G

maternally expressed 3

increases expression

cerous chloride results in increased expression of MEG3 mRNA

NCBI chr 6:128,491,808...128,524,010

G

macrophage migration inhibitory factor

increases expression

cerous chloride results in increased expression of MIF

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

G

myeloperoxidase

affects expression

cerous chloride affects the expression of MPO mRNA

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

mitochondrial inner membrane protein MPV17

multiple interactions
decreases expression

[cerous chloride co-treated with lanthanum chloride] results in increased expression of MPV17 mRNA
cerous chloride results in decreased expression of MPV17 mRNA

NCBI chr 6:25,221,668...25,236,241
Ensembl chr 6:25,222,896...25,236,244

G

methionine sulfoxide reductase A

decreases expression

cerous chloride results in decreased expression of MSRA mRNA

NCBI chr15:38,363,459...38,677,406
Ensembl chr15:38,351,445...38,676,585

G

metallothionein 2A

multiple interactions
decreases expression
increases expression

cerous chloride promotes the reaction [Zinc binds to MT2 protein]
cerous chloride results in decreased expression of MT2 mRNA
cerous chloride results in increased expression of MT2 protein

PMID:15964310 PMID:16204935 PMID:23573234

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

myotubularin related protein 4

increases expression

cerous chloride results in increased expression of MTMR4 mRNA

NCBI chr10:72,393,411...72,416,342
Ensembl chr10:72,392,551...72,416,342

G

myeloid-associated differentiation marker-like 2

decreases expression

cerous chloride results in decreased expression of MYADML2 mRNA

NCBI chr10:105,922,557...105,927,867
Ensembl chr10:105,925,947...105,927,575

G

myosin heavy chain 11

decreases expression

cerous chloride results in decreased expression of MYH11 mRNA

NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459

G

myomesin 3

increases expression

cerous chloride results in increased expression of MYOM3 mRNA

NCBI chr 5:147,992,737...148,043,282
Ensembl chr 5:147,992,737...148,043,274

G

myb-like, SWIRM and MPN domains 1

increases expression

cerous chloride results in increased expression of MYSM1 mRNA

NCBI chr 5:109,761,345...109,826,652
Ensembl chr 5:109,776,286...109,819,967

G

asparaginyl-tRNA synthetase 2, mitochondrial

increases expression

cerous chloride results in increased expression of NARS2 mRNA

NCBI chr 1:151,300,446...151,412,086
Ensembl chr 1:151,300,467...151,413,521

G

neutrophil cytosolic factor 1

multiple interactions

[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF1 mRNA

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

G

neutrophil cytosolic factor 2

affects expression
multiple interactions

cerous chloride affects the expression of NCF2 mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NCF2 mRNA

NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277

G

NDRG family member 2

increases expression

cerous chloride results in increased expression of NDRG2 mRNA

NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626

G

NDRG family member 3

increases expression

cerous chloride results in increased expression of NDRG3 mRNA

NCBI chr 3:145,587,505...145,650,896
Ensembl chr 3:145,548,041...145,650,873

G

neuronal growth regulator 1

increases expression

cerous chloride results in increased expression of NEGR1 mRNA

NCBI chr 2:245,624,460...246,359,605
Ensembl chr 2:245,624,435...246,356,730

G

neuraminidase 1

decreases expression

cerous chloride results in decreased expression of NEU1 mRNA

NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745

G

nuclear factor of activated T-cells 5

increases expression

cerous chloride results in increased expression of NFAT5 mRNA

NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675

G

nuclear factor kappa B subunit 1

increases expression

cerous chloride results in increased expression of NFKB1 mRNA; cerous chloride results in increased expression of NFKB1 protein

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

nuclear factor kappa B subunit 2

increases expression

cerous chloride results in increased expression of NFKB2 mRNA; cerous chloride results in increased expression of NFKB2 protein

NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213

G

NFKB inhibitor beta

decreases expression

cerous chloride results in decreased expression of NFKBIB mRNA; cerous chloride results in decreased expression of NFKBIB protein

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

G

NIPBL, cohesin loading factor

increases expression

cerous chloride results in increased expression of NIPBL mRNA

NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899

G

NKD inhibitor of WNT signaling pathway 2

increases expression

cerous chloride results in increased expression of NKD2 mRNA

NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821

G

natural killer cell triggering receptor

increases expression

cerous chloride results in increased expression of NKTR mRNA

NCBI chr 8:121,380,010...121,420,495
Ensembl chr 8:121,382,436...121,418,314

G

NK6 homeobox 2

decreases expression

cerous chloride results in decreased expression of NKX6-2 mRNA

NCBI chr 1:194,380,149...194,383,533
Ensembl chr 1:194,381,975...194,383,515

G

nicotinamide N-methyltransferase

affects expression

cerous chloride affects the expression of NNMT mRNA

NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655

G

nitric oxide synthase 2

decreases expression
multiple interactions

cerous chloride results in decreased expression of NOS2 mRNA
[cerous chloride co-treated with lanthanum chloride] results in increased expression of NOS2 mRNA

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

nuclear receptor subfamily 1, group H, member 3

increases expression

cerous chloride results in increased expression of NR1H3 mRNA

NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722

G

nuclear receptor binding protein 2

increases expression

cerous chloride results in increased expression of NRBP2 mRNA

NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230

G

neurexin 3

increases expression

cerous chloride results in increased expression of NRXN3 mRNA

NCBI chr 6:107,641,760...109,272,849
Ensembl chr 6:107,641,780...109,272,044

G

5' nucleotidase, ecto

decreases expression

cerous chloride results in decreased expression of NT5E mRNA

NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881

G

netrin G2

increases expression

cerous chloride results in increased expression of NTNG2 mRNA

NCBI chr 3:12,492,574...12,551,104
Ensembl chr 3:12,492,639...12,545,890

G

nudix hydrolase 1

multiple interactions
decreases expression

[cerous chloride co-treated with lanthanum chloride] results in decreased expression of NUDT1 mRNA
cerous chloride results in decreased expression of NUDT1 mRNA

NCBI chr12:14,302,514...14,309,559
Ensembl chr12:14,302,694...14,305,826

G

Obg-like ATPase 1

increases expression

cerous chloride results in increased expression of OLA1 mRNA

NCBI chr 3:57,966,896...58,085,955
Ensembl chr 3:57,966,896...58,084,480

G

one cut homeobox 2

increases expression

cerous chloride results in increased expression of ONECUT2 mRNA

NCBI chr18:57,831,647...57,890,884
Ensembl chr18:57,832,111...57,879,629

G

protocadherin beta 20

increases expression

cerous chloride results in increased expression of PCDHB20 mRNA

NCBI chr18:29,211,878...29,215,272
Ensembl chr18:29,211,883...29,215,258

G

proliferating cell nuclear antigen

affects expression
multiple interactions

cerous chloride affects the expression of PCNA protein
[cerous chloride co-treated with lanthanum chloride] affects the expression of PCNA protein

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

pyruvate dehydrogenase kinase 2

decreases expression

cerous chloride results in decreased expression of PDK2 mRNA

NCBI chr10:79,972,550...79,987,074
Ensembl chr10:79,972,556...79,987,085

G

period circadian regulator 3

increases expression

cerous chloride results in increased expression of PER3 mRNA

NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607

G

peptidase inhibitor 16

decreases expression

cerous chloride results in decreased expression of PI16 mRNA

NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383

G

phospholipase C, delta 1

increases expression

cerous chloride results in increased expression of PLCD1 mRNA

NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186

G

polynucleotide kinase 3'-phosphatase

decreases expression

cerous chloride results in decreased expression of PNKP mRNA

NCBI chr 1:95,341,465...95,346,921
Ensembl chr 1:95,341,620...95,346,920

G

podocalyxin-like

increases expression

cerous chloride results in increased expression of PODXL mRNA

NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899

G

peroxiredoxin 1

multiple interactions
decreases expression

[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PRDX1 mRNA
cerous chloride results in decreased expression of PRDX1 mRNA

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

peroxiredoxin 2

decreases expression

cerous chloride results in decreased expression of PRDX2 mRNA

NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194

G

peroxiredoxin 5

multiple interactions

[cerous chloride co-treated with lanthanum chloride] results in increased expression of PRDX5 mRNA

NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268

G

phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1

multiple interactions

[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PREX1 mRNA

NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688

G

pre-mRNA processing factor 38B

increases expression

cerous chloride results in increased expression of PRPF38B mRNA

NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250

G

prostaglandin-endoperoxide synthase 2

decreases expression

cerous chloride results in decreased expression of PTGS2 mRNA

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

parathyroid hormone 2

increases expression

cerous chloride results in increased expression of PTH2 mRNA

NCBI chr 1:95,666,525...95,667,174

G

protein phosphatase 2 phosphatase activator

increases expression

cerous chloride results in increased expression of PTPA mRNA

NCBI chr 3:13,689,742...13,720,287
Ensembl chr 3:13,689,741...13,722,549

G

peroxidasin

multiple interactions
decreases expression

[cerous chloride co-treated with lanthanum chloride] results in decreased expression of PXDN mRNA
cerous chloride results in decreased expression of PXDN mRNA

NCBI chr 6:46,580,749...46,658,345
Ensembl chr 6:46,580,761...46,658,345

G

Rap guanine nucleotide exchange factor like 1

increases expression

cerous chloride results in increased expression of RAPGEFL1 mRNA

NCBI chr10:83,793,711...83,810,373
Ensembl chr10:83,793,694...83,810,371

G

RNA binding motif protein 8A

decreases expression

cerous chloride results in decreased expression of RBM8A mRNA

NCBI chr 2:184,165,189...184,167,959
Ensembl chr 2:184,165,193...184,167,959

G

RELA proto-oncogene, NF-kB subunit

increases expression

cerous chloride results in increased expression of RELA mRNA; cerous chloride results in increased expression of RELA protein

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

retinol saturase

decreases expression

cerous chloride results in decreased expression of RETSAT mRNA

NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310

G

regulator of G-protein signaling 11

increases expression

cerous chloride results in increased expression of RGS11 mRNA

NCBI chr10:15,222,804...15,231,062
Ensembl chr10:15,222,803...15,231,060

G

Rpgrip1-like

decreases expression

cerous chloride results in decreased expression of RPGRIP1L mRNA

NCBI chr19:15,692,189...15,785,083
Ensembl chr19:15,692,150...15,785,083

G

retrotransposon-like 1

increases expression

cerous chloride results in increased expression of RTL1 mRNA

NCBI chr 6:128,543,904...128,549,384
Ensembl chr 6:128,543,939...128,549,182

G

S100 calcium binding protein A8

increases expression

cerous chloride results in increased expression of S100A8 mRNA

NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643

G

S100 calcium binding protein A9

increases expression

cerous chloride results in increased expression of S100A9 mRNA

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

G

spermidine/spermine N1-acetyltransferase family member 2

increases expression

cerous chloride results in increased expression of SAT2 mRNA

NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224

G

scavenger receptor class A, member 3

decreases expression

cerous chloride results in decreased expression of SCARA3 mRNA

NCBI chr15:40,139,873...40,172,866
Ensembl chr15:40,140,161...40,172,894

G

secretoglobin family 1A member 1

increases expression

cerous chloride results in increased expression of SCGB1A1 mRNA

NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610

G

selenoprotein P

multiple interactions

[cerous chloride co-treated with lanthanum chloride] results in increased expression of SELENOP mRNA

NCBI chr 2:52,498,123...52,508,409
Ensembl chr 2:52,498,339...52,508,852

G

splicing factor 1

increases expression

cerous chloride results in increased expression of SF1 mRNA

NCBI chr 1:203,670,016...203,683,432
Ensembl chr 1:203,670,018...203,684,330

G

splicing factor proline and glutamine rich

increases expression

cerous chloride results in increased expression of SFPQ mRNA

NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472

G

sirtuin 2

multiple interactions
decreases expression
increases expression

[cerous chloride co-treated with lanthanum chloride] results in increased expression of SIRT2 mRNA
cerous chloride results in decreased expression of SIRT2 mRNA
cerous chloride results in increased expression of SIRT2 mRNA

NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975

G

sirtuin 7

decreases expression

cerous chloride results in decreased expression of SIRT7 mRNA

NCBI chr10:105,896,476...105,903,301
Ensembl chr10:105,896,476...105,903,172

G

solute carrier family 5 member 7

decreases expression

cerous chloride results in decreased expression of SLC5A7 mRNA

NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258

G

sphingomyelin phosphodiesterase, acid-like 3B

decreases expression

cerous chloride results in decreased expression of SMPDL3B mRNA

NCBI chr 5:144,944,618...144,966,703
Ensembl chr 5:144,944,636...144,966,720

G

synuclein, beta

increases expression

cerous chloride results in increased expression of SNCB mRNA

NCBI chr17:9,846,802...9,855,013
Ensembl chr17:9,846,802...9,855,012

G

syntrophin, beta 2

increases expression

cerous chloride results in increased expression of SNTB2 mRNA

NCBI chr19:34,831,657...34,922,325
Ensembl chr19:34,831,584...34,914,113

G

small nuclear ribonucleoprotein 13

decreases expression

cerous chloride results in decreased expression of SNU13 mRNA

NCBI chr 7:113,565,293...113,570,887
Ensembl chr 7:113,565,295...113,570,872
Ensembl chr 1:113,565,295...113,570,872

G

superoxide dismutase 1

decreases activity

cerous chloride results in decreased activity of SOD1 protein

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

decreases activity
multiple interactions

cerous chloride results in decreased activity of SOD2 protein
[cerous chloride co-treated with lanthanum chloride] results in increased expression of SOD2 mRNA

PMID:15964310 PMID:28954213

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

sprouty RTK signaling antagonist 4

increases expression

cerous chloride results in increased expression of SPRY4 mRNA

NCBI chr18:30,436,513...30,451,426
Ensembl chr18:30,436,443...30,453,004

G

sequestosome 1

multiple interactions
affects expression

[cerous chloride co-treated with lanthanum chloride] results in increased expression of SQSTM1 mRNA
cerous chloride affects the expression of SQSTM1 mRNA

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

serine racemase

increases expression

cerous chloride results in increased expression of SRR mRNA

NCBI chr10:59,769,563...59,786,688
Ensembl chr10:59,769,571...59,787,011

G

sulfiredoxin 1

multiple interactions

[cerous chloride co-treated with lanthanum chloride] results in increased expression of SRXN1 mRNA

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

serine/threonine kinase 25

decreases expression
multiple interactions

cerous chloride results in decreased expression of STK25 mRNA
[cerous chloride co-treated with lanthanum chloride] results in decreased expression of STK25 mRNA

NCBI chr 9:94,161,834...94,174,095
Ensembl chr 9:94,161,836...94,174,244

G

spermatid perinuclear RNA binding protein

increases expression

cerous chloride results in increased expression of STRBP mRNA

NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949

G

small ubiquitin-like modifier 3

increases expression

cerous chloride results in increased expression of SUMO3 mRNA

NCBI chr20:11,010,140...11,020,850
Ensembl chr20:11,007,148...11,020,877
Ensembl chr20:11,007,148...11,020,877

G

spectrin repeat containing nuclear envelope family member 4

increases expression

cerous chloride results in increased expression of SYNE4 mRNA

NCBI chr 1:85,569,409...85,573,775
Ensembl chr 1:85,569,545...85,573,760

G

teneurin transmembrane protein 2

increases expression

cerous chloride results in increased expression of TENM2 mRNA

NCBI chr10:20,480,662...21,706,415
Ensembl chr10:20,481,854...21,705,597

G

transcription factor Dp-1

increases expression

cerous chloride results in increased expression of TFDP1 mRNA

NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817

G

transforming growth factor, beta 1

increases expression

cerous chloride results in increased expression of TGFB1

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

TIA1 cytotoxic granule-associated RNA binding protein

increases expression

cerous chloride results in increased expression of TIA1 mRNA

NCBI chr 4:118,852,765...118,883,252
Ensembl chr 4:118,852,837...118,880,586

G

tolloid-like 1

decreases expression

cerous chloride results in decreased expression of TLL1 mRNA

NCBI chr16:25,509,146...25,710,330
Ensembl chr16:25,509,146...25,709,543

G

toll-like receptor 2

increases expression

cerous chloride results in increased expression of TLR2 mRNA; cerous chloride results in increased expression of TLR2 protein

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

toll-like receptor 4

increases expression

cerous chloride results in increased expression of TLR4 mRNA; cerous chloride results in increased expression of TLR4 protein

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

transmembrane protein 219

increases expression

cerous chloride results in increased expression of TMEM219 mRNA

NCBI chr 1:181,496,195...181,509,259
Ensembl chr 1:181,496,192...181,534,472

G

tumor necrosis factor

increases expression

cerous chloride results in increased expression of TNF; cerous chloride results in increased expression of TNF mRNA; cerous chloride results in increased expression of TNF protein

PMID:21656643 PMID:23712967

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

tankyrase 2

increases expression

cerous chloride results in increased expression of TNKS2 mRNA

NCBI chr 1:234,567,888...234,621,079
Ensembl chr 1:234,567,858...234,621,079

G

transcriptional repressor GATA binding 1

increases expression

cerous chloride results in increased expression of TRPS1 mRNA

NCBI chr 7:81,916,668...82,142,733
Ensembl chr 7:81,921,601...82,141,905

G

TSPO associated protein 1

increases expression

cerous chloride results in increased expression of TSPOAP1 mRNA

NCBI chr10:72,554,220...72,586,402
Ensembl chr10:72,560,980...72,586,412

G

thioredoxin 1

increases expression

cerous chloride results in increased expression of TXN mRNA

NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629

G

thioredoxin reductase 1

increases expression

cerous chloride results in increased expression of TXNRD1 mRNA

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

thioredoxin reductase 2

decreases expression

cerous chloride results in decreased expression of TXNRD2 mRNA

NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156

G

ubiquitin conjugating enzyme E2 V1

increases expression

cerous chloride results in increased expression of UBE2V1 mRNA

NCBI chr 3:156,317,339...156,340,198
Ensembl chr 3:156,316,781...156,340,273

G

uncoupling protein 2

multiple interactions
decreases expression

[cerous chloride co-treated with lanthanum chloride] affects the expression of UCP2 mRNA
cerous chloride results in decreased expression of UCP2 mRNA

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

G

unc-13 homolog B

increases expression

cerous chloride results in increased expression of UNC13B mRNA

NCBI chr 5:57,288,999...57,504,110
Ensembl chr 5:57,289,227...57,502,926

G

ubiquinol-cytochrome c reductase binding protein

increases expression

cerous chloride results in increased expression of UQCRB mRNA

NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150

G

vimentin-type intermediate filament associated coiled-coil protein

increases expression

cerous chloride results in increased expression of VMAC mRNA

NCBI chr 9:1,546,747...1,550,417
Ensembl chr 9:1,546,747...1,549,771

G

X inactive specific transcript

decreases expression

cerous chloride results in decreased expression of XIST mRNA

NCBI chr X:68,474,987...68,492,500

G

zeta chain of T cell receptor associated protein kinase 70

affects expression

cerous chloride affects the expression of ZAP70 mRNA

NCBI chr 9:38,989,750...39,011,701
Ensembl chr 9:38,989,750...39,011,700

G

zinc finger protein 24

increases expression

cerous chloride results in increased expression of ZNF24 mRNA

NCBI chr18:15,295,687...15,307,319
Ensembl chr18:15,298,290...15,306,799

G

zinc finger protein 512B

increases expression

cerous chloride results in increased expression of ZNF512B mRNA

NCBI chr 3:168,687,520...168,698,067
Ensembl chr 3:168,687,521...168,698,091

gadobutrol

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

decreases expression

gadobutrol results in decreased expression of ADIPOQ mRNA

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

fatty acid binding protein 4

decreases expression

gadobutrol results in decreased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

peroxisome proliferator-activated receptor gamma

decreases expression

gadobutrol results in decreased expression of PPARG mRNA

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

gadodiamide hydrate

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

adiponectin, C1Q and collagen domain containing

decreases expression

gadodiamide results in decreased expression of ADIPOQ mRNA; gadodiamide results in decreased expression of ADIPOQ protein

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

AKT serine/threonine kinase 1

increases phosphorylation
multiple interactions

gadodiamide results in increased phosphorylation of AKT1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of AKT1 protein]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aldehyde dehydrogenase 1 family, member A1

increases expression

gadodiamide results in increased expression of ALDH1A1 mRNA

NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961

G

ankyrin repeat domain 22

increases expression

gadodiamide results in increased expression of ANKRD22 mRNA

NCBI chr 1:231,639,035...231,670,537
Ensembl chr 1:231,639,314...231,670,381

G

ATM serine/threonine kinase

increases expression

gadodiamide results in increased expression of ATM mRNA

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATPase phospholipid transporting 8B1

increases expression

gadodiamide results in increased expression of ATP8B1 mRNA

NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396

G

C-C motif chemokine ligand 2

increases expression
increases secretion

gadodiamide results in increased expression of CCL2 mRNA
gadodiamide results in increased expression of CCL2 mRNA; gadodiamide results in increased expression of CCL2 protein
gadodiamide results in increased secretion of CCL2 protein

PMID:20938346 PMID:20959327

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 4

increases expression

gadodiamide results in increased expression of CCL4 protein

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

C-C motif chemokine ligand 7

increases expression

gadodiamide results in increased expression of CCL7 protein

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

centrosomal protein 15

increases expression

gadodiamide results in increased expression of CEP15 mRNA

NCBI chr15:12,815,159...12,835,115
Ensembl chr15:12,818,385...12,833,838

G

C-X-C motif chemokine ligand 10

increases expression
increases secretion

gadodiamide results in increased expression of CXCL10 mRNA
gadodiamide results in increased expression of CXCL10 protein
gadodiamide results in increased secretion of CXCL10 protein

PMID:20938346 PMID:20959327

NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975

G

C-X-C motif chemokine ligand 11

increases secretion
increases expression

gadodiamide results in increased secretion of CXCL11 protein
gadodiamide results in increased expression of CXCL11 mRNA

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

G

C-X-C motif chemokine ligand 12

increases expression

gadodiamide results in increased expression of CXCL12 mRNA

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 9

increases expression

gadodiamide results in increased expression of CXCL9 mRNA

NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435

G

fatty acid binding protein 4

decreases expression

gadodiamide results in decreased expression of FABP4 mRNA; gadodiamide results in decreased expression of FABP4 protein

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

indoleamine 2,3-dioxygenase 1

increases expression

gadodiamide results in increased expression of IDO1 mRNA

NCBI chr16:67,430,654...67,442,726
Ensembl chr16:67,430,578...67,442,730

G

interferon-induced protein 44-like

increases expression

gadodiamide results in increased expression of IFI44L mRNA

NCBI chr 2:240,668,742...240,706,425
Ensembl chr 2:240,668,713...240,706,359

G

interferon-induced protein with tetratricopeptide repeats 3

increases expression

gadodiamide results in increased expression of IFIT3 mRNA

NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307

G

interferon gamma

increases expression

gadodiamide results in increased expression of IFNG mRNA; gadodiamide results in increased expression of IFNG protein

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interleukin 13

increases expression

gadodiamide results in increased expression of IL13 mRNA; gadodiamide results in increased expression of IL13 protein

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 1 alpha

increases expression

gadodiamide results in increased expression of IL1A protein

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 4

increases expression
affects expression

gadodiamide results in increased expression of IL4 protein
gadodiamide affects the expression of IL4 mRNA

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 4 induced 1

increases expression

gadodiamide results in increased expression of IL4I1 mRNA

NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562

G

interleukin 6

affects expression
increases expression

gadodiamide affects the expression of IL6 protein
gadodiamide results in increased expression of IL6 mRNA

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

KIT ligand

increases expression

gadodiamide results in increased expression of KITLG protein

NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214

G

mitogen activated protein kinase 1

multiple interactions
increases phosphorylation

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK1 protein]

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

multiple interactions
increases phosphorylation

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [gadodiamide results in increased phosphorylation of MAPK3 protein]

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

matrix metallopeptidase 1

multiple interactions
increases expression

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of MMP1 protein]
gadodiamide results in increased expression of MMP1 mRNA; gadodiamide results in increased expression of MMP1 protein

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

G

nitric oxide synthase 2

increases expression

gadodiamide results in increased expression of NOS2 protein

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

neurexophilin and PC-esterase domain family, member 3

increases expression

gadodiamide results in increased expression of NXPE3 mRNA

NCBI chr11:44,726,905...44,777,694
Ensembl chr11:44,727,069...44,777,694

G

peroxisome proliferator-activated receptor gamma

decreases expression

gadodiamide results in decreased expression of PPARG mRNA; gadodiamide results in decreased expression of PPARG protein

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

RELA proto-oncogene, NF-kB subunit

increases localization

gadodiamide results in increased localization of RELA protein

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

ras homolog family member Q

increases expression

gadodiamide results in increased expression of RHOQ mRNA

NCBI chr 6:7,613,632...7,652,047

G

Ras-like without CAAX 1

increases expression

gadodiamide results in increased expression of RIT1 mRNA

NCBI chr 2:174,180,742...174,195,455
Ensembl chr 2:174,180,848...174,195,455

G

ring finger protein 125

increases expression

gadodiamide results in increased expression of RNF125 mRNA

NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983

G

radical S-adenosyl methionine domain containing 2

increases expression

gadodiamide results in increased expression of RSAD2 mRNA

NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699

G

solute carrier family 39 member 10

increases expression

gadodiamide results in increased expression of SLC39A10 mRNA

NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325

G

sialophorin

increases expression

gadodiamide results in increased expression of SPN mRNA

NCBI chr 1:181,746,937...181,759,564
Ensembl chr 1:181,746,429...181,759,628

G

secreted phosphoprotein 1

increases expression

gadodiamide results in increased expression of SPP1 protein

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

transforming growth factor, beta 1

increases expression

gadodiamide results in increased expression of TGFB1 mRNA; gadodiamide results in increased expression of TGFB1 protein

PMID:19404939 PMID:20938346

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

TIMP metallopeptidase inhibitor 1

increases expression
multiple interactions

gadodiamide results in increased expression of TIMP1 mRNA; gadodiamide results in increased expression of TIMP1 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [gadodiamide results in increased expression of TIMP1 protein]; U 0126 inhibits the reaction [gadodiamide results in increased expression of TIMP1 protein]

PMID:19561517 PMID:20938346

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

ubiquitin D

increases expression

gadodiamide results in increased expression of UBD mRNA

NCBI chr20:1,385,487...1,387,438
Ensembl chr20:1,385,864...1,408,639
Ensembl chr20:1,385,864...1,408,639

G

vascular endothelial growth factor A

increases expression

gadodiamide results in increased expression of VEGFA mRNA; gadodiamide results in increased expression of VEGFA protein

PMID:19404939 PMID:20938346

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

WD repeat domain 5

increases expression

gadodiamide results in increased expression of WDR5 mRNA

NCBI chr 3:10,836,964...10,856,682
Ensembl chr 3:10,837,025...10,856,671

G

X-linked inhibitor of apoptosis

increases expression

gadodiamide results in increased expression of XIAP mRNA

NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700

G

zinc finger protein 652

increases expression

gadodiamide results in increased expression of ZNF652 mRNA

NCBI chr10:80,626,555...80,706,397
Ensembl chr10:80,649,400...80,698,674

gadolinium trichloride

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 4

multiple interactions

gadolinium chloride inhibits the reaction [perfluorodecanoic acid results in increased expression of ABCC4 mRNA]

NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283

G

acetyl-CoA carboxylase alpha

multiple interactions

gadolinium chloride promotes the reaction [Ethanol results in decreased expression of ACACA protein]
[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of ACACA mRNA

PMID:28882574 PMID:34878122

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acyl-CoA thioesterase 1

multiple interactions

gadolinium chloride promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of ACOT1 mRNA]

NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163

G

actin alpha 2, smooth muscle

multiple interactions

gadolinium chloride inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

adhesion G protein-coupled receptor E1

multiple interactions

[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of ADGRE1 mRNA
gadolinium chloride inhibits the reaction [Ethanol results in increased expression of ADGRE1 protein]

PMID:25813056 PMID:28882574

NCBI chr 9:2,242,476...2,398,000
Ensembl chr 9:2,242,474...2,398,000

G

adiponectin, C1Q and collagen domain containing

decreases expression

gadolinium chloride results in decreased expression of ADIPOQ mRNA

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

apolipoprotein B

multiple interactions

gadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of APOB mRNA]

NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497

G

activating transcription factor 4

affects expression

gadolinium chloride affects the expression of ATF4 mRNA

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 6

multiple interactions
increases expression
affects expression

Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ATF6 protein]
gadolinium chloride affects the expression of ATF6 mRNA

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

BCL2, apoptosis regulator

multiple interactions

[gadolinium chloride results in increased abundance of Gadolinium] which results in decreased expression of BCL2 protein

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

basic helix-loop-helix ARNT like 1

multiple interactions

[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of BMAL1 protein

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

G

bone morphogenetic protein 2

multiple interactions

gadolinium chloride promotes the reaction [Carbon Tetrachloride results in increased expression of BMP2 mRNA]

NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397

G

caspase 3

multiple interactions

[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of CASP3 mRNA

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

catalase

multiple interactions

gadolinium chloride inhibits the reaction [[Triiodothyronine co-treated with Hexachlorocyclohexane] results in decreased activity of CAT protein]

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

C-C motif chemokine ligand 2

multiple interactions

gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of CCL2 mRNA]; gadolinium chloride inhibits the reaction [[Fructose co-treated with Copper deficiency] results in increased expression of CCL2 protein]

PMID:25813056 PMID:26177832

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

cyclin E1

increases expression

gadolinium chloride results in increased expression of CCNE1

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

CD163 molecule

multiple interactions

[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of CD163 mRNA; gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of CD163 mRNA]

PMID:25813056 PMID:26177832

NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878

G

Cd68 molecule

multiple interactions

gadolinium chloride inhibits the reaction [[Dietary Fats co-treated with bromodichloromethane] results in increased expression of CD68 mRNA]
[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of CD68 mRNA; [gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of CD68 protein; gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of CD68 mRNA]

PMID:23438451 PMID:25813056 PMID:26177832

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

carnitine palmitoyltransferase 1A

multiple interactions

gadolinium chloride promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of CPT1A mRNA]
[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of CPT1A mRNA

PMID:22648072 PMID:34878122

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

C-X-C motif chemokine ligand 1

multiple interactions

gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of CXCL1 mRNA]

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 2

multiple interactions

gadolinium chloride inhibits the reaction [[Progesterone co-treated with Halothane] results in increased expression of CXCL2 mRNA]
gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of CXCL2 mRNA]

PMID:22157104 PMID:26177832

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

multiple interactions

gadolinium chloride inhibits the reaction [Progesterone promotes the reaction [Halothane results in increased expression of CXCL1 mRNA]]; gadolinium chloride inhibits the reaction [Progesterone results in increased expression of CXCL1 mRNA]

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions

gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP1A2 protein]

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 2, subfamily b, polypeptide 1

multiple interactions

gadolinium chloride inhibits the reaction [Phenobarbital results in increased expression of CYP2B1 mRNA]; gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2B1 mRNA]; gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2B1 protein]

PMID:10918498 PMID:18202523

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily b, polypeptide 2

multiple interactions

gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2B2 mRNA]; gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2B2 protein]

NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566

G

cytochrome P450, subfamily 2, polypeptide 11

multiple interactions

gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP2C11 protein]

NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 mRNA]; gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP2E1 protein]

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP3A2 mRNA]; gadolinium chloride inhibits the reaction [Styrene results in increased expression of CYP3A2 protein]; gadolinium chloride inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased activity of and results in decreased expression of CYP3A2 protein]

PMID:18079364 PMID:18202523

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily a, polypeptide 1

multiple interactions

gadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of CYP4A1 mRNA]

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

DNA-damage inducible transcript 3

multiple interactions
increases expression
affects expression

Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of DDIT3 protein]
gadolinium chloride affects the expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

eukaryotic translation initiation factor 2 alpha kinase 3

increases expression

gadolinium chloride results in increased expression of EIF2AK3 protein

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

endoplasmic reticulum to nucleus signaling 1

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein]

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

fatty acid binding protein 4

decreases expression

gadolinium chloride results in decreased expression of FABP4 mRNA

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

fatty acid synthase

multiple interactions

[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of FASN mRNA
gadolinium chloride promotes the reaction [Ethanol results in decreased expression of FASN protein]

PMID:25813056 PMID:28882574

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

glutamic--pyruvic transaminase

multiple interactions

gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of GPT protein]; gadolinium chloride inhibits the reaction [Vitamin A results in increased activity of GPT protein]
gadolinium chloride inhibits the reaction [Amiodarone promotes the reaction [Dexamethasone results in increased expression of GPT protein]]

PMID:8627517 PMID:25900201 PMID:26177832

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

hepcidin antimicrobial peptide

increases expression

gadolinium chloride results in increased expression of HAMP

NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891

G

hypoxia inducible factor 1 subunit alpha

multiple interactions

[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of HIF1A mRNA

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

hemojuvelin BMP co-receptor

decreases expression

gadolinium chloride results in decreased expression of HJV

NCBI chr 2:184,065,944...184,069,851
Ensembl chr 2:184,065,970...184,069,850

G

high mobility group box 1

multiple interactions

gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased secretion of HMGB1 protein]

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

3-hydroxy-3-methylglutaryl-CoA synthase 2

multiple interactions

gadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of HMGCS2 mRNA]

NCBI chr 2:185,875,609...185,903,505
Ensembl chr 2:185,875,616...185,902,130

G

heat shock protein family A (Hsp70) member 1A

multiple interactions

gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of HSPA1A mRNA]; gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of HSPA1A protein]

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 5

increases expression
multiple interactions
affects expression

gadolinium chloride results in increased expression of HSPA5 protein
Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of HSPA5 protein]
gadolinium chloride affects the expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

intercellular adhesion molecule 1

multiple interactions

gadolinium chloride inhibits the reaction [[Progesterone co-treated with Halothane] results in increased expression of ICAM1 mRNA]

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

interferon gamma

affects expression
increases expression

gadolinium chloride affects the expression of IFNG protein
gadolinium chloride results in increased expression of IFNG mRNA

PMID:15590129 PMID:19404939

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

insulin-like growth factor 1

multiple interactions

gadolinium chloride inhibits the reaction [Lipopolysaccharides results in decreased expression of IGF1 protein]

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 3

multiple interactions

gadolinium chloride inhibits the reaction [Lipopolysaccharides results in decreased expression of IGFBP3 protein]

NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083

G

interleukin 10

multiple interactions

gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of IL10 mRNA]; gadolinium chloride inhibits the reaction [perfluoro-n-nonanoic acid results in decreased expression of IL10 protein]

PMID:22648072 PMID:26177832

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 13

increases expression

gadolinium chloride results in increased expression of IL13 mRNA

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 1 alpha

multiple interactions

gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A mRNA]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of IL1A protein]

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

increases expression
multiple interactions

gadolinium chloride results in increased expression of IL1B
[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of IL1B mRNA
[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of IL1B mRNA; gadolinium chloride inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of IL1B protein]

PMID:19721414 PMID:22648072 PMID:25813056 PMID:34878122

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 4

affects expression

gadolinium chloride affects the expression of IL4 mRNA; gadolinium chloride affects the expression of IL4 protein

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 6

multiple interactions
increases expression

[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of IL6 mRNA; gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of IL6 mRNA]; gadolinium chloride inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of IL6 protein]
[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of IL6 mRNA
gadolinium chloride inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
gadolinium chloride results in increased expression of IL6
gadolinium chloride results in increased expression of IL6 mRNA

PMID:12127824 PMID:12963478 PMID:19404939 PMID:19721414 PMID:24849676 More...

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

lipase E, hormone sensitive type

multiple interactions

gadolinium chloride inhibits the reaction [Ethanol results in increased phosphorylation of LIPE protein]

NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310

G

lymphotoxin beta

increases expression

gadolinium chloride results in increased expression of LTB mRNA

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

G

mitogen activated protein kinase 1

decreases phosphorylation
multiple interactions
increases activity

gadolinium chloride results in decreased phosphorylation of MAPK1 protein
gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased phosphorylation of MAPK1 protein]
gadolinium chloride results in increased activity of MAPK1 protein
Pertussis Toxin inhibits the reaction [gadolinium chloride results in decreased phosphorylation of MAPK1 protein]

PMID:12493575 PMID:21605080 PMID:26177832

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

decreases phosphorylation
multiple interactions
increases activity

gadolinium chloride results in decreased phosphorylation of MAPK3 protein
gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased phosphorylation of MAPK3 protein]
Pertussis Toxin inhibits the reaction [gadolinium chloride results in decreased phosphorylation of MAPK3 protein]
gadolinium chloride results in increased activity of MAPK3 protein

PMID:12493575 PMID:21605080 PMID:26177832

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

matrix metallopeptidase 13

multiple interactions
increases expression

[Dimethylnitrosamine co-treated with gadolinium chloride] results in increased expression of MMP13 mRNA; SB 203580 inhibits the reaction [gadolinium chloride results in increased expression of MMP13 mRNA]

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

matrix metallopeptidase 14

multiple interactions
increases expression

[Dimethylnitrosamine co-treated with gadolinium chloride] results in increased expression of MMP14 mRNA
gadolinium chloride results in increased expression of MMP14 mRNA; gadolinium chloride results in increased expression of MMP14 protein

NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864

G

matrix metallopeptidase 9

increases expression
multiple interactions

gadolinium chloride results in increased expression of MMP9 mRNA
SB 203580 inhibits the reaction [gadolinium chloride results in increased expression of MMP9 mRNA]

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

myeloperoxidase

multiple interactions

gadolinium chloride inhibits the reaction [Thioacetamide results in increased activity of MPO protein]

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

NFE2 like bZIP transcription factor 2

multiple interactions

[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of NFE2L2 mRNA

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor kappa B subunit 1

multiple interactions

gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased activity of NFKB1 protein]
[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of NFKB1 mRNA

PMID:15025948 PMID:34878122

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

nitric oxide synthase 2

increases expression

gadolinium chloride results in increased expression of NOS2 mRNA

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

platelet derived growth factor subunit A

decreases expression

gadolinium chloride results in decreased expression of PDGFA mRNA

NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497

G

platelet derived growth factor subunit B

decreases expression

gadolinium chloride results in decreased expression of PDGFB mRNA

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

G

peroxisome proliferator activated receptor alpha

multiple interactions

gadolinium chloride promotes the reaction [perfluoro-n-nonanoic acid results in increased expression of PPARA mRNA]

NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346

G

peroxisome proliferator-activated receptor gamma

decreases expression

gadolinium chloride results in decreased expression of PPARG mRNA

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

protein tyrosine kinase 2

increases activity

gadolinium chloride results in increased activity of PTK2

NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783

G

RB transcriptional corepressor 1

increases phosphorylation

gadolinium chloride results in increased phosphorylation of RB1 protein

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased activity of RELA protein]
[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of RELA protein

PMID:15025948 PMID:34878122

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

S100 calcium binding protein A8

multiple interactions

gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of S100A8 mRNA]

NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643

G

S100 calcium binding protein A9

multiple interactions

gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of S100A9 mRNA]

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

G

stearoyl-CoA desaturase

multiple interactions

gadolinium chloride promotes the reaction [[Fructose co-treated with Copper deficiency] results in decreased expression of SCD1 mRNA]
gadolinium chloride promotes the reaction [Ethanol results in decreased expression of SCD1 protein]

PMID:25813056 PMID:28882574

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

solute carrier family 40 member 1

decreases expression

gadolinium chloride results in decreased expression of SLC40A1

NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481

G

secreted phosphoprotein 1

multiple interactions

[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of SPP1 mRNA

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

sequestosome 1

multiple interactions

[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of SQSTM1 mRNA

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

sterol regulatory element binding transcription factor 1

multiple interactions

gadolinium chloride inhibits the reaction [[Fructose co-treated with Copper deficiency] results in increased expression of SREBF1 protein]

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

G

transforming growth factor, beta 1

multiple interactions
increases expression
affects expression

gadolinium chloride inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]; gadolinium chloride inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]; gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of TGFB1 mRNA]
[gadolinium chloride results in increased abundance of Gadolinium] which results in increased expression of TGFB1 mRNA
gadolinium chloride results in increased expression of TGFB1 protein
gadolinium chloride results in increased expression of TGFB1 mRNA
gadolinium chloride affects the expression of TGFB1 mRNA

PMID:11408273 PMID:15590129 PMID:15964588 PMID:19404939 PMID:34878122

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

toll-like receptor 4

multiple interactions

[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TLR4 mRNA; gadolinium chloride inhibits the reaction [[Buthionine Sulfoximine results in increased susceptibility to Methimazole] which results in increased expression of TLR4 protein]

PMID:25813056 PMID:26177832

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

tumor necrosis factor

multiple interactions
decreases expression
increases expression

[gadolinium chloride co-treated with Fructose co-treated with Copper deficiency] results in decreased expression of TNF mRNA; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF mRNA]; gadolinium chloride inhibits the reaction [Hexachlorocyclohexane results in increased expression of TNF protein]; gadolinium chloride inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; gadolinium chloride inhibits the reaction [perfluoro-n-nonanoic acid results in increased expression of TNF protein]; gadolinium chloride inhibits the reaction [Thioacetamide results in increased expression of TNF protein]
gadolinium trichloride inhibits the reaction [estriol enhances the reaction [lipopolysaccharide increases expression of Tnf mRNA in liver]]
gadolinium chloride inhibits the reaction [lead acetate promotes the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; gadolinium chloride inhibits the reaction [perfluorodecanoic acid results in increased expression of TNF protein]
gadolinium chloride results in increased expression of TNF
gadolinium chloride results in increased expression of TNF mRNA

CTD
RGD

PMID:12127824 PMID:12963478 PMID:14687926 PMID:15025948 PMID:15590129 More...

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 11B

increases expression

gadolinium chloride results in increased expression of TNFRSF11B mRNA

NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538

G

TNF receptor superfamily member 1A

increases expression

gadolinium chloride results in increased expression of TNFRSF1A mRNA

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

G

TNF superfamily member 10

increases expression

gadolinium chloride results in increased expression of TNFSF10 mRNA

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

G

TNF superfamily member 11

decreases expression

gadolinium chloride results in decreased expression of TNFSF11 mRNA

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

G

uncoupling protein 2

multiple interactions

gadolinium chloride inhibits the reaction [Carbon Tetrachloride results in increased expression of UCP2 mRNA]

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

G

vascular endothelial growth factor A

increases expression

gadolinium chloride results in increased expression of VEGFA mRNA; gadolinium chloride results in increased expression of VEGFA protein

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

X-box binding protein 1

increases splicing

gadolinium chloride results in increased splicing of XBP1 mRNA

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

motexafin gadolinium

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase

multiple interactions
decreases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of AGL mRNA
motexafin gadolinium results in decreased expression of AGL mRNA

NCBI chr 2:204,705,053...204,760,966
Ensembl chr 2:204,705,053...204,760,828

G

aldehyde dehydrogenase 5 family, member A1

multiple interactions
increases expression

motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of ALDH5A1 mRNA]
motexafin gadolinium results in increased expression of ALDH5A1 mRNA

NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677

G

aldehyde dehydrogenase 6 family, member A1

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of ALDH6A1 mRNA
Zinc Acetate inhibits the reaction [motexafin gadolinium results in decreased expression of ALDH6A1 mRNA]

NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656

G

Rho GTPase activating protein 17

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of ARHGAP17 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ARHGAP17 mRNA

NCBI chr 1:177,807,579...177,897,027
Ensembl chr 1:177,807,583...177,896,854

G

activating transcription factor 3

multiple interactions
increases expression

motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of ATF3 mRNA]
motexafin gadolinium results in increased expression of ATF3 mRNA

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

ATM serine/threonine kinase

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of ATM mRNA]
motexafin gadolinium results in increased expression of ATM mRNA

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

ATR serine/threonine kinase

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of ATR mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ATR mRNA

NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136

G

BTB domain and CNC homolog 1

increases expression
multiple interactions

motexafin gadolinium results in increased expression of BACH1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BACH1 mRNA

NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447

G

BAG cochaperone 3

multiple interactions
increases expression

motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of BAG3 mRNA]
motexafin gadolinium results in increased expression of BAG3 mRNA

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

Bcl-2 binding component 3

multiple interactions

[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of BBC3 protein]

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

baculoviral IAP repeat-containing 5

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of BIRC5 mRNA]
motexafin gadolinium results in increased expression of BIRC5 mRNA

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

base methyltransferase of 25S rRNA 2 homolog

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BMT2 mRNA
motexafin gadolinium results in increased expression of BMT2 mRNA

NCBI chr 4:41,881,630...41,945,472
Ensembl chr 4:41,879,993...41,945,539

G

BCL2 interacting protein 3

increases expression
multiple interactions

motexafin gadolinium results in increased expression of BNIP3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

BCL2 interacting protein 3 like

increases expression
multiple interactions

motexafin gadolinium results in increased expression of BNIP3L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of BNIP3L mRNA

NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803

G

calnexin

increases expression
multiple interactions

motexafin gadolinium results in increased expression of CANX mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CANX mRNA

NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821

G

caspase 3

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of CASP3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CASP3 mRNA

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

core-binding factor subunit beta

increases expression
multiple interactions

motexafin gadolinium results in increased expression of CBFB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CBFB mRNA

NCBI chr19:33,049,162...33,092,752
Ensembl chr19:33,049,172...33,092,751

G

cyclin J

multiple interactions
decreases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CCNJ mRNA
motexafin gadolinium results in decreased expression of CCNJ mRNA

NCBI chr 1:239,659,588...239,677,367

G

cell division cycle 16

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of CDC16 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC16 mRNA

NCBI chr16:75,773,026...75,796,586
Ensembl chr16:75,773,028...75,796,550

G

cell division cycle 25C

increases expression
multiple interactions

motexafin gadolinium results in increased expression of CDC25C mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDC25C mRNA

NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185

G

cell division cycle 27

increases expression
multiple interactions

motexafin gadolinium results in increased expression of CDC27 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of CDC27 mRNA

NCBI chr10:89,400,720...89,449,816
Ensembl chr10:89,400,940...89,449,736

G

cell division cycle 5-like

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of CDC5L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDC5L mRNA

NCBI chr 9:15,564,949...15,603,453
Ensembl chr 9:15,564,767...15,603,450

G

cell division cycle associated 2

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of CDCA2 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDCA2 mRNA

NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611

G

cyclin-dependent kinase 19

increases expression

motexafin gadolinium results in increased expression of CDK19 mRNA

NCBI chr20:43,770,409...43,910,629
Ensembl chr20:43,770,409...43,910,628

G

cyclin dependent kinase 2

multiple interactions
increases expression

motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of CDK2 mRNA]
motexafin gadolinium results in increased expression of CDK2 mRNA

NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403

G

cyclin-dependent kinase inhibitor 1A

multiple interactions

[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CDKN1A mRNA]

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression
multiple interactions

motexafin gadolinium results in increased expression of CDKN1B mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CDKN1B mRNA

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

cystathionine gamma-lyase

increases expression
multiple interactions

motexafin gadolinium results in increased expression of CTH mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CTH mRNA

NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234

G

cullin 3

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of CUL3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of CUL3 mRNA

NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462

G

cytochrome b5 reductase 1

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of CYB5R1 mRNA
motexafin gadolinium results in increased expression of CYB5R1 mRNA

NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458

G

death-associated protein kinase 3

multiple interactions
decreases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DAPK3 mRNA]
motexafin gadolinium results in decreased expression of DAPK3 mRNA

NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558

G

DNA-damage inducible transcript 3

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DDIT3 mRNA]
motexafin gadolinium results in increased expression of DDIT3 mRNA

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

increases expression
multiple interactions

motexafin gadolinium results in increased expression of DDIT4 mRNA
motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of DDIT4 mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of DDIT4 mRNA]

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

death effector domain containing 2

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of DEDD2 mRNA]
motexafin gadolinium results in increased expression of DEDD2 mRNA

NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714

G

DNA fragmentation factor subunit beta

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of DFFB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of DFFB mRNA

NCBI chr 5:164,522,446...164,534,733
Ensembl chr 5:164,522,463...164,534,628

G

7-dehydrocholesterol reductase

decreases expression

motexafin gadolinium results in decreased expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

DnaJ heat shock protein family (Hsp40) member B1

multiple interactions
increases expression

motexafin gadolinium inhibits the reaction [Zinc Acetate results in decreased expression of DNAJB1 mRNA]
motexafin gadolinium results in increased expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member B4

increases expression
multiple interactions

motexafin gadolinium results in increased expression of DNAJB4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB4 mRNA

NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089

G

DnaJ heat shock protein family (Hsp40) member B6

increases expression
multiple interactions

motexafin gadolinium results in increased expression of DNAJB6 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of DNAJB6 mRNA

NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659

G

DnaJ heat shock protein family (Hsp40) member C3

multiple interactions
increases expression

motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of DNAJC3 mRNA]
motexafin gadolinium results in increased expression of DNAJC3 mRNA

NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181

G

E2F transcription factor 1

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F1 mRNA
motexafin gadolinium results in increased expression of E2F1 mRNA

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

E2F transcription factor 3

increases expression
multiple interactions

motexafin gadolinium results in increased expression of E2F3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of E2F3 mRNA

NCBI chr17:34,601,756...34,679,139
Ensembl chr17:34,601,830...34,676,253

G

egl-9 family hypoxia-inducible factor 1

increases expression
multiple interactions

motexafin gadolinium results in increased expression of EGLN1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of EGLN1 mRNA

NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777

G

elongator acetyltransferase complex subunit 1

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of ELP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of ELP1 mRNA

NCBI chr 5:71,453,338...71,505,833
Ensembl chr 5:71,456,310...71,505,762

G

enolase 1

increases expression

motexafin gadolinium results in increased expression of ENO1 mRNA

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

Fas associated via death domain

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of FADD mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FADD mRNA

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

G

Fas apoptotic inhibitory molecule

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of FAIM mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of FAIM mRNA

NCBI chr 8:99,543,877...99,569,499
Ensembl chr 8:99,542,405...99,560,562

G

family with sequence similarity 162, member A

increases expression
multiple interactions

motexafin gadolinium results in increased expression of FAM162A mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FAM162A mRNA

NCBI chr11:64,680,978...64,709,865
Ensembl chr11:64,680,323...64,711,239

G

fatty acid synthase

decreases expression

motexafin gadolinium results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

forkhead box O3

increases expression
multiple interactions

motexafin gadolinium results in increased expression of FOXO3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of FOXO3 mRNA

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

G

glutamate cysteine ligase, modifier subunit

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GCLM mRNA
motexafin gadolinium results in increased expression of GCLM mRNA

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

glutaminase

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of GLS mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GLS mRNA

NCBI chr 9:49,344,616...49,416,900
Ensembl chr 9:49,344,781...49,416,900

G

G protein-coupled receptor 146

increases expression

motexafin gadolinium results in increased expression of GPR146 mRNA

NCBI chr12:15,251,936...15,267,217
Ensembl chr12:15,251,813...15,267,206

G

glutamic--pyruvic transaminase 2

increases expression

motexafin gadolinium results in increased expression of GPT2 mRNA

NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610

G

glutathione peroxidase 1

multiple interactions

[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of GPX1 mRNA]

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione-disulfide reductase

increases expression
multiple interactions

motexafin gadolinium results in increased expression of GSR mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of GSR mRNA

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

general transcription factor IIIC subunit 2

increases expression

motexafin gadolinium results in increased expression of GTF3C2 mRNA

NCBI chr 6:25,196,439...25,221,338
Ensembl chr 6:25,197,268...25,220,490

G

HMG-box transcription factor 1

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HBP1 mRNA
motexafin gadolinium results in increased expression of HBP1 mRNA

NCBI chr 6:48,529,633...48,555,775
Ensembl chr 6:48,529,372...48,555,787

G

hypoxia inducible factor 1 subunit alpha

multiple interactions
increases expression

[motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HIF1A protein
motexafin gadolinium results in increased expression of HIF1A protein

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

hypoxia inducible lipid droplet-associated

increases expression
multiple interactions

motexafin gadolinium results in increased expression of HILPDA mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HILPDA mRNA

NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557

G

homeodomain interacting protein kinase 1

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HIPK1 mRNA]
motexafin gadolinium results in increased expression of HIPK1 mRNA

NCBI chr 2:191,248,817...191,299,787
Ensembl chr 2:191,248,817...191,298,902

G

helicase-like transcription factor

multiple interactions
decreases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of HLTF mRNA
motexafin gadolinium results in decreased expression of HLTF mRNA

NCBI chr 2:102,549,724...102,609,492
Ensembl chr 2:102,549,724...102,609,327

G

heme oxygenase 1

multiple interactions
increases expression

[motexafin gadolinium co-treated with Zinc Acetate] results in increased expression of HMOX1 protein; motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HMOX1 mRNA]
motexafin gadolinium results in increased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

harakiri, BCL2 interacting protein

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HRK mRNA
motexafin gadolinium results in increased expression of HRK mRNA

NCBI chr12:38,387,484...38,409,652

G

heat shock protein 90 alpha family class B member 1

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSP90AB1 mRNA
motexafin gadolinium results in increased expression of HSP90AB1 mRNA

NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488

G

heat shock protein family A (Hsp70) member 1A

multiple interactions
increases expression

motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1A mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1A mRNA]

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

multiple interactions
increases expression

motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPA1B mRNA]; Zinc Acetate promotes the reaction [motexafin gadolinium results in increased expression of HSPA1B mRNA]

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 4

increases expression
multiple interactions

motexafin gadolinium results in increased expression of HSPA4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4 mRNA

NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001

G

heat shock protein family A (Hsp70) member 4 like

increases expression
multiple interactions

motexafin gadolinium results in increased expression of HSPA4L mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of HSPA4L mRNA

NCBI chr 2:123,740,384...123,793,088
Ensembl chr 2:123,740,384...123,793,084

G

heat shock protein family B (small) member 1

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPB1 mRNA]
motexafin gadolinium results in increased expression of HSPB1 mRNA

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

heat shock protein family D (Hsp60) member 1

multiple interactions
increases expression

motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of HSPD1 mRNA]
motexafin gadolinium results in increased expression of HSPD1 mRNA

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

G

heat shock protein family H (Hsp110) member 1

increases expression
multiple interactions

motexafin gadolinium results in increased expression of HSPH1 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of HSPH1 mRNA]

NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224

G

inhibitor of DNA binding 2

increases expression
multiple interactions

motexafin gadolinium results in increased expression of ID2 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

inhibitor of nuclear factor kappa B kinase subunit epsilon

increases expression
multiple interactions

motexafin gadolinium results in increased expression of IKBKE mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IKBKE mRNA

NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143

G

interferon regulatory factor 2 binding protein 2

increases expression
multiple interactions

motexafin gadolinium results in increased expression of IRF2BP2 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of IRF2BP2 mRNA

NCBI chr19:54,559,417...54,565,096
Ensembl chr19:54,560,128...54,566,642

G

JunD proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

motexafin gadolinium results in increased expression of JUND mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of JUND mRNA

NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799

G

lysine demethylase 3A

increases expression

motexafin gadolinium results in increased expression of KDM3A mRNA

NCBI chr 4:103,630,907...103,675,073
Ensembl chr 4:103,630,908...103,675,073

G

MDM2 proto-oncogene

increases expression
multiple interactions

motexafin gadolinium results in increased expression of MDM2 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MDM2 mRNA]

NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915

G

MOB kinase activator 1A

increases expression
multiple interactions

motexafin gadolinium results in increased expression of MOB1A mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of MOB1A mRNA]

NCBI chr 4:115,831,581...115,848,561
Ensembl chr 4:115,831,551...115,848,561

G

metallothionein 1

multiple interactions

[Zinc co-treated with motexafin gadolinium] results in increased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 1, pseudogene 3

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of MT1E mRNA
motexafin gadolinium results in increased expression of MT1E mRNA

PMID:15867382 PMID:16357179

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 1M

multiple interactions
increases expression

motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT1HL1 mRNA]
motexafin gadolinium results in increased expression of MT1HL1 mRNA

PMID:15867382 PMID:16357179

NCBI chr20:3,159,037...3,159,409
Ensembl chr 5:119,728,811...119,730,073

G

metallothionein 2A

multiple interactions
increases expression

motexafin gadolinium promotes the reaction [Zinc Acetate results in increased expression of MT2A mRNA]
motexafin gadolinium results in increased expression of MT2A mRNA

PMID:15867382 PMID:16357179

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

MYD88, innate immune signal transduction adaptor

multiple interactions
decreases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of MYD88 mRNA
motexafin gadolinium results in decreased expression of MYD88 mRNA

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

NAD kinase

increases expression
multiple interactions

motexafin gadolinium results in increased expression of NADK mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NADK mRNA

NCBI chr 5:166,145,708...166,176,328
Ensembl chr 5:166,145,481...166,176,322

G

neurofibromin 1

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of NF1 mRNA
motexafin gadolinium results in increased expression of NF1 mRNA

NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658

G

nischarin

decreases expression

motexafin gadolinium results in decreased expression of NISCH mRNA

NCBI chr16:6,364,370...6,400,675
Ensembl chr16:6,364,374...6,400,668

G

nuclear receptor subfamily 1, group D, member 2

increases expression
multiple interactions

motexafin gadolinium results in increased expression of NR1D2 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of NR1D2 mRNA]

NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553

G

prolyl 4-hydroxylase subunit beta

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of P4HB mRNA]
motexafin gadolinium results in increased expression of P4HB mRNA

NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500

G

programmed cell death 11

decreases expression

motexafin gadolinium results in decreased expression of PDCD11 mRNA

NCBI chr 1:245,980,840...246,021,999
Ensembl chr 1:245,980,880...246,021,999

G

programmed cell death 4

increases expression
multiple interactions

motexafin gadolinium results in increased expression of PDCD4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PDCD4 mRNA

NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275

G

programmed cell death 5

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of PDCD5 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PDCD5 mRNA

NCBI chr 1:88,305,869...88,311,200
Ensembl chr 1:88,305,869...88,311,200

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

increases expression
multiple interactions

motexafin gadolinium results in increased expression of PFKFB3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB3 mRNA

NCBI chr17:66,983,629...67,064,702
Ensembl chr17:66,983,686...67,063,125

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4

increases expression
multiple interactions

motexafin gadolinium results in increased expression of PFKFB4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PFKFB4 mRNA

NCBI chr 8:109,643,558...109,687,006
Ensembl chr 8:109,643,937...109,685,634

G

phosphoglycerate kinase 1

increases expression
multiple interactions

motexafin gadolinium results in increased expression of PGK1 mRNA
motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PGK1 mRNA]

NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418

G

putative homeodomain transcription factor 2

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PHTF2 mRNA]
motexafin gadolinium results in increased expression of PHTF2 mRNA

NCBI chr 4:14,215,190...14,330,549
Ensembl chr 4:14,215,263...14,330,513

G

protein inhibitor of activated STAT, 1

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of PIAS1 mRNA]
motexafin gadolinium results in increased expression of PIAS1 mRNA

NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905

G

phosphoinositide-3-kinase interacting protein 1

increases expression
multiple interactions

motexafin gadolinium results in increased expression of PIK3IP1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PIK3IP1 mRNA

NCBI chr14:78,204,668...78,216,616
Ensembl chr14:78,204,053...78,216,608

G

phorbol-12-myristate-13-acetate-induced protein 1

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PMAIP1 mRNA
motexafin gadolinium results in increased expression of PMAIP1 mRNA

NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429

G

protein kinase cAMP-activated catalytic subunit beta

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of PRKACB mRNA
motexafin gadolinium results in increased expression of PRKACB mRNA

NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198

G

protein kinase C, delta

decreases expression

motexafin gadolinium results in decreased expression of PRKCD mRNA

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

G

protein kinase D2

decreases expression

motexafin gadolinium results in decreased expression of PRKD2 mRNA

NCBI chr 1:77,513,625...77,542,386
Ensembl chr 1:77,513,986...77,542,376

G

protein kinase, DNA-activated, catalytic subunit

increases expression

motexafin gadolinium results in increased expression of PRKDC mRNA

NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952

G

peptidyl-tRNA hydrolase 2

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of PTRH2 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of PTRH2 mRNA

NCBI chr10:71,505,113...71,515,297
Ensembl chr10:71,504,956...71,515,398

G

RB transcriptional corepressor 1

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of RB1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

RCC1 and BTB domain containing protein 2

multiple interactions
decreases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of RCBTB2 mRNA
motexafin gadolinium results in decreased expression of RCBTB2 mRNA

NCBI chr15:48,319,809...48,364,441
Ensembl chr15:48,323,866...48,383,750

G

RELB proto-oncogene, NF-kB subunit

increases expression
multiple interactions

motexafin gadolinium results in increased expression of RELB mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of RELB mRNA

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

ring finger protein 19B

increases expression

motexafin gadolinium results in increased expression of RNF19B mRNA

NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380

G

selenoprotein W

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SELENOW mRNA
motexafin gadolinium results in increased expression of SELENOW mRNA

NCBI chr 1:76,599,441...76,604,514
Ensembl chr 1:76,598,779...76,604,724
Ensembl chr 1:76,598,779...76,604,724

G

sestrin 2

multiple interactions
increases expression

[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA; [Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SESN2 mRNA; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SESN2 mRNA]
motexafin gadolinium results in increased expression of SESN2 mRNA

PMID:16357179 PMID:20530418

NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260

G

solute carrier family 16 member 1

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC16A1 mRNA]
motexafin gadolinium results in increased expression of SLC16A1 mRNA

NCBI chr 2:192,123,755...192,144,617
Ensembl chr 2:192,124,289...192,144,611

G

solute carrier family 16, member 6

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC16A6 mRNA
motexafin gadolinium results in increased expression of SLC16A6 mRNA

NCBI chr10:94,424,377...94,447,482
Ensembl chr10:94,426,244...94,448,779

G

solute carrier family 1 member 4

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC1A4 mRNA]
motexafin gadolinium results in increased expression of SLC1A4 mRNA

NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418

G

solute carrier family 30 member 1

multiple interactions
increases expression

[Zinc co-treated with motexafin gadolinium] results in increased expression of SLC30A1 mRNA; motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC30A1 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC30A1 mRNA]

PMID:15867382 PMID:16357179

NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910

G

solute carrier family 38, member 2

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of SLC38A2 mRNA]; Zinc Acetate affects the reaction [motexafin gadolinium results in increased expression of SLC38A2 mRNA]

NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436

G

solute carrier family 39 member 10

multiple interactions
affects expression

[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A10 mRNA
motexafin gadolinium affects the expression of SLC39A10 mRNA

NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325

G

solute carrier family 39 member 14

increases expression
multiple interactions

motexafin gadolinium results in increased expression of SLC39A14 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC39A14 mRNA

NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524

G

solute carrier family 39, member 9

increases expression
multiple interactions

motexafin gadolinium results in increased expression of SLC39A9 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC39A9 mRNA

NCBI chr 6:100,291,537...100,330,419
Ensembl chr 6:100,291,573...100,330,408

G

solute carrier family 3 member 2

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC3A2 mRNA
motexafin gadolinium results in increased expression of SLC3A2 mRNA

NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931

G

solute carrier family 43 member 1

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of SLC43A1 mRNA
motexafin gadolinium results in increased expression of SLC43A1 mRNA

NCBI chr 3:69,920,586...69,946,768
Ensembl chr 3:69,920,649...69,946,768

G

solute carrier family 7 member 1

multiple interactions
increases expression

[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A1 mRNA
motexafin gadolinium results in increased expression of SLC7A1 mRNA

NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849

G

solute carrier family 7 member 11

increases expression
multiple interactions

motexafin gadolinium results in increased expression of SLC7A11 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of SLC7A11 mRNA

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of SMARCA4 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA4 mRNA

NCBI chr 8:20,167,717...20,258,975
Ensembl chr 8:20,167,717...20,258,975

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of SMARCA5 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of SMARCA5 mRNA

NCBI chr19:27,271,918...27,304,594
Ensembl chr19:27,271,148...27,304,594

G

T-cell activation RhoGTPase activating protein

increases expression
multiple interactions

motexafin gadolinium results in increased expression of TAGAP mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TAGAP mRNA

NCBI chr 1:47,170,725...47,179,705
Ensembl chr 1:47,170,725...47,179,792

G

transferrin receptor

multiple interactions
increases expression

motexafin gadolinium affects the reaction [Zinc Acetate results in increased expression of TFRC mRNA]
motexafin gadolinium results in increased expression of TFRC mRNA

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

TNF alpha induced protein 8

decreases expression
multiple interactions

motexafin gadolinium results in decreased expression of TNFAIP8 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFAIP8 mRNA

NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517

G

TNF receptor superfamily member 17

multiple interactions
decreases expression

[Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TNFRSF17 mRNA
motexafin gadolinium results in decreased expression of TNFRSF17 mRNA

NCBI chr10:4,301,023...4,306,889
Ensembl chr10:4,301,038...4,306,788

G

TNF receptor superfamily member 1A

increases expression
multiple interactions

motexafin gadolinium results in increased expression of TNFRSF1A mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TNFRSF1A mRNA

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

G

TNF superfamily member 8

multiple interactions
increases expression

motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of TNFSF8 mRNA]
motexafin gadolinium results in increased expression of TNFSF8 mRNA

NCBI chr 5:77,250,942...77,277,364
Ensembl chr 5:77,251,373...77,277,421

G

TNFAIP3 interacting protein 2

decreases expression

motexafin gadolinium results in decreased expression of TNIP2 mRNA

NCBI chr14:76,228,350...76,245,553
Ensembl chr14:76,228,371...76,275,265

G

tumor protein p53

multiple interactions

[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein; Acetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; nutlin 3 inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tribbles pseudokinase 3

increases expression
multiple interactions

motexafin gadolinium results in increased expression of TRIB3 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TRIB3 mRNA

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

thioredoxin reductase 1

increases expression
multiple interactions

motexafin gadolinium results in increased expression of TXNRD1 mRNA
[Zinc Acetate co-treated with motexafin gadolinium] results in increased expression of TXNRD1 mRNA

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

vascular endothelial growth factor A

increases expression
multiple interactions

motexafin gadolinium results in increased expression of VEGFA mRNA
[Zinc Acetate co-treated with motexafin gadolinium] affects the expression of VEGFA mRNA

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

von Hippel-Lindau tumor suppressor

multiple interactions
increases expression

motexafin gadolinium inhibits the reaction [Zinc Acetate results in increased expression of VHL mRNA]
motexafin gadolinium results in increased expression of VHL mRNA

NCBI chr 4:146,772,483...146,779,376
Ensembl chr 4:146,772,468...146,779,377

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19811
chemical entity	19840
molecular entity	19809
transition element molecular entity	16829
f-block molecular entity	511
lanthanoid molecular entity	511
lanthanoid coordination entity	454
cerium coordination entity +	236
europium coordination entity +	0
gadolinium coordination entity +	242
Path 2
Term	Annotations
CHEBI ontology	19811
subatomic particle	19809
composite particle	19809
hadron	19840
baryon	19809
nucleon	19809
atomic nucleus	19809
atom	19809
metal atom	17706
transition element atom	17076
transition element molecular entity	16829
f-block molecular entity	511
lanthanoid molecular entity	511
lanthanoid coordination entity	454
cerium coordination entity +	236
europium coordination entity +	0
gadolinium coordination entity +	242

paths to the root