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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:immunosuppressive agent
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Accession:CHEBI:35705 term browser browse the term
Definition:An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Synonyms:related_synonym: immunosuppressant;   immunosuppressive agents;   inmunosupresor


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    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19876
        role 19851
          biological role 19849
            immunomodulator 15052
              immunosuppressive agent 13930
                (+)-dexrazoxane + 167
                4'-demethyldeoxypodophyllotoxin 0
                4-hydroperoxycyclophosphamide 74
                5-fluorouracil 1465
                IC202A 0
                IC202B 0
                IC202C 0
                ascomycin 2
                auranofin 42
                azaserine 0
                azathioprine 639
                baricitinib 9
                betamethasone + 25
                betamethasone phosphate 0
                brasilicardin A 0
                brasilinolide A 0
                brazilein 6
                brequinar 1
                brequinar sodium 0
                chetomin 4
                chlorambucil 53
                cimifoetiside A 0
                cimifoetiside B 0
                cladribine 22
                cyclophosphamide + 754
                cyclophosphamide hydrate 0
                cyclosporin A + 8356
                cytarabine 585
                demethylzeylasteral 0
                dexamethasone + 4572
                dexrazoxane hydrochloride 0
                dimethyl sulfate 5
                everolimus 40
                fentin chloride 21
                fingolimod + 0
                fingolimod hydrochloride 71
                fingolimod phosphate 0
                fludarabine phosphate 0
                flunisolide 8
                gemcitabine + 282
                gemcitabine hydrochloride 0
                ginsenoside Rd + 45
                gliotoxin 29
                hydrocortamate + 0
                ifosfamide 248
                leflunomide 2626
                lymphostin 0
                melphalan 275
                methotrexate 2397
                mycophenolate mofetil 1
                mycophenolate sodium 0
                mycophenolic acid + 112
                myriocin 12
                neosartoricin 0
                phenanthridone 20
                physalin F 0
                prednisolone + 238
                prednisone + 38
                psora 4 0
                scoparone 16
                sirolimus + 520
                sotrastaurin 4
                spermine + 69
                stevastelin B 0
                stevastelin B3 0
                tacrolimus (anhydrous) + 434
                tacrolimus hydrate 431
                thalidomide + 470
                thiamphenicol 1
                triptonide 5704
                undecylprodigiosin 0
                vincaleukoblastine + 1330
                wilformine 0
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19876
        role 19851
          application 19687
            pharmaceutical 19514
              drug 19514
                immunomodulator 15052
                  immunosuppressive agent 13930
                    (+)-dexrazoxane + 167
                    4'-demethyldeoxypodophyllotoxin 0
                    4-hydroperoxycyclophosphamide 74
                    5-fluorouracil 1465
                    IC202A 0
                    IC202B 0
                    IC202C 0
                    ascomycin 2
                    auranofin 42
                    azaserine 0
                    azathioprine 639
                    baricitinib 9
                    betamethasone + 25
                    betamethasone phosphate 0
                    brasilicardin A 0
                    brasilinolide A 0
                    brazilein 6
                    brequinar 1
                    brequinar sodium 0
                    chetomin 4
                    chlorambucil 53
                    cimifoetiside A 0
                    cimifoetiside B 0
                    cladribine 22
                    cyclophosphamide + 754
                    cyclophosphamide hydrate 0
                    cyclosporin A + 8356
                    cytarabine 585
                    demethylzeylasteral 0
                    dexamethasone + 4572
                    dexrazoxane hydrochloride 0
                    dimethyl sulfate 5
                    everolimus 40
                    fentin chloride 21
                    fingolimod + 0
                    fingolimod hydrochloride 71
                    fingolimod phosphate 0
                    fludarabine phosphate 0
                    flunisolide 8
                    gemcitabine + 282
                    gemcitabine hydrochloride 0
                    ginsenoside Rd + 45
                    gliotoxin 29
                    hydrocortamate + 0
                    ifosfamide 248
                    leflunomide 2626
                    lymphostin 0
                    melphalan 275
                    methotrexate 2397
                    mycophenolate mofetil 1
                    mycophenolate sodium 0
                    mycophenolic acid + 112
                    myriocin 12
                    neosartoricin 0
                    phenanthridone 20
                    physalin F 0
                    prednisolone + 238
                    prednisone + 38
                    psora 4 0
                    scoparone 16
                    sirolimus + 520
                    sotrastaurin 4
                    spermine + 69
                    stevastelin B 0
                    stevastelin B3 0
                    tacrolimus (anhydrous) + 434
                    tacrolimus hydrate 431
                    thalidomide + 470
                    thiamphenicol 1
                    triptonide 5704
                    undecylprodigiosin 0
                    vincaleukoblastine + 1330
                    wilformine 0
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