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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:antiplatyhelmintic drug
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Accession:CHEBI:35684 term browser browse the term
Definition:An agent used to treat cestode, trematode, or other flatworm infestations in man or animals.
Synonyms:related_synonym: antiplatyhelmintic agent;   antiplatyhelmintic drugs


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bithionol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Iyd iodotyrosine deiodinase multiple interactions ISO Bithionol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Bithionol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
JBrowse link
G Thra thyroid hormone receptor alpha increases activity EXP Bithionol results in increased activity of THRA protein CTD PMID:22015988 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Thrb thyroid hormone receptor beta increases activity EXP Bithionol results in increased activity of THRB protein CTD PMID:22015988 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of A2M mRNA CTD PMID:17547211 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance
increases secretion
multiple interactions
ISO ABCC1 protein affects the susceptibility to Antimony Potassium Tartrate
ABCC1 protein results in decreased susceptibility to Antimony Potassium Tartrate
ABCC1 protein results in increased secretion of Antimony Potassium Tartrate
[MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Antimony Potassium Tartrate; Glutathione affects the reaction [ABCC1 protein results in increased secretion of Antimony Potassium Tartrate]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Antimony Potassium Tartrate]; verlukast inhibits the reaction [ABCC1 protein results in increased secretion of Antimony Potassium Tartrate]
CTD PMID:10025956 PMID:10348353 PMID:11278867 PMID:12018890 PMID:12731862 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions
EXP
ISO
Antimony Potassium Tartrate results in increased expression of ABCC2 mRNA; Antimony Potassium Tartrate results in increased expression of ABCC2 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of ABCC2 mRNA
CTD PMID:11408547 PMID:32076005 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of ABCC3 mRNA CTD PMID:32076005 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Acp2 acid phosphatase 2, lysosomal decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ACP2 mRNA CTD PMID:17547211 NCBI chr 3:77,175,022...77,185,180
Ensembl chr 3:77,175,895...77,185,680
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ACSL1 mRNA CTD PMID:17547211 NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
JBrowse link
G Adm adrenomedullin increases expression ISO Antimony Potassium Tartrate results in increased expression of ADM mRNA CTD PMID:17547211 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B decreases expression
increases expression
ISO Antimony Potassium Tartrate results in decreased expression of AKR1B1 mRNA
Antimony Potassium Tartrate results in increased expression of AKR1B1 mRNA
CTD PMID:17547211 PMID:28713220 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of AKR1B10 mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of AKR1B10 mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Antimony Potassium Tartrate results in increased expression of AKR1C2 protein CTD PMID:28713220 NCBI chr17:65,759,778...65,808,013
Ensembl chr17:65,759,788...65,775,764
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of AKR1C3 mRNA; Antimony Potassium Tartrate results in increased expression of AKR1C3 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of AKR1C3 mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of ALDH3A2 mRNA CTD PMID:32076005 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Aldh3b2 aldehyde dehydrogenase 3 family, member B2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of ALDH3B2 mRNA CTD PMID:32076005 NCBI chr 1:201,250,260...201,264,699 JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ALDH6A1 mRNA CTD PMID:17547211 NCBI chr 6:104,077,975...104,098,636
Ensembl chr 6:104,077,979...104,098,656
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Antimony Potassium Tartrate results in increased expression of ALDOA mRNA CTD PMID:28713220 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression ISO Antimony Potassium Tartrate results in increased expression of ALDOC mRNA CTD PMID:28713220 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Ar androgen receptor increases phosphorylation ISO Antimony Potassium Tartrate results in increased phosphorylation of AR protein CTD PMID:29462692 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ATP2B1 mRNA CTD PMID:17547211 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression ISO Antimony Potassium Tartrate results in decreased expression of AZGP1 mRNA CTD PMID:17547211 NCBI chr12:16,930,990...16,939,333
Ensembl chr12:16,931,024...16,939,091
JBrowse link
G Barx2 BARX homeobox 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of BARX2 mRNA CTD PMID:32076005 NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of BAX protein CTD PMID:32920012 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO
666-15 compound promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in decreased expression of BCL2 protein]; [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in decreased expression of BCL2 protein CTD PMID:32920012 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP12 mRNA]; Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP2 mRNA] CTD PMID:28713220 NCBI chr17:26,318,121...26,469,034
Ensembl chr17:26,318,569...26,470,365
JBrowse link
G Btf3 basic transcription factor 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of BTF3 mRNA CTD PMID:32076005 NCBI chr 2:29,659,764...29,666,898
Ensembl chr 2:29,659,231...29,666,879
JBrowse link
G Btg2 BTG anti-proliferation factor 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of BTG2 mRNA CTD PMID:32076005 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Calml5 calmodulin-like 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CALML5 mRNA CTD PMID:28713220 NCBI chr17:66,394,433...66,395,390 JBrowse link
G Calr calreticulin multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of CALR mRNA CTD PMID:32076005 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased cleavage of CASP3 protein CTD PMID:32920012 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cbr1 carbonyl reductase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of CBR1 mRNA CTD PMID:32076005 NCBI chr11:32,860,618...32,862,981
Ensembl chr11:32,908,950...32,911,393
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Antimony Potassium Tartrate results in increased expression of CCNB2 mRNA CTD PMID:17547211 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Antimony Potassium Tartrate results in increased expression of CDKN1A mRNA CTD PMID:17547211 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of CDKN2B mRNA CTD PMID:32076005 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of CDKN3 mRNA CTD PMID:17547211 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of CEBPA mRNA CTD PMID:32076005 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cfb complement factor B decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CFB mRNA CTD PMID:17547211 NCBI chr20:3,970,643...3,976,510 JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of CKS2 mRNA CTD PMID:17547211 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clgn calmegin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CLGN mRNA CTD PMID:17547211 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CLPTM1 mRNA CTD PMID:17547211 NCBI chr 1:79,289,478...79,321,079
Ensembl chr 1:79,289,477...79,321,092
JBrowse link
G Cnbp CCHC-type zinc finger, nucleic acid binding protein multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of CNBP mRNA CTD PMID:32076005 NCBI chr 4:120,302,768...120,311,694
Ensembl chr 4:120,302,771...120,311,637
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO
EXP
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein; pyrazolanthrone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein]
CTD PMID:32920012 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of CYP1B1 mRNA CTD PMID:32076005 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Dazap1 DAZ associated protein 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of DAZAP1 mRNA CTD PMID:17547211 NCBI chr 7:9,423,673...9,448,116
Ensembl chr 7:9,424,178...9,538,818
JBrowse link
G Dcp1a decapping mRNA 1A increases expression ISO Antimony Potassium Tartrate results in increased expression of DCP1A mRNA CTD PMID:17547211 NCBI chr16:5,656,788...5,702,151
Ensembl chr16:5,656,773...5,702,140
JBrowse link
G Dhrs9 dehydrogenase/reductase 9 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DHRS9 mRNA CTD PMID:32076005 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DNAJB1 mRNA CTD PMID:32076005 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb4 DnaJ heat shock protein family (Hsp40) member B4 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of DNAJB4 mRNA CTD PMID:32076005 NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089
JBrowse link
G Dsc1 desmocollin 1 decreases expression
multiple interactions
ISO Antimony Potassium Tartrate results in decreased expression of DSC1 mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSC1 mRNA; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSC1 mRNA]
CTD PMID:28713220 PMID:32076005 NCBI chr18:11,499,936...11,556,801
Ensembl chr18:11,502,003...11,528,494
JBrowse link
G Dsg1 desmoglein 1 multiple interactions ISO 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSG1 mRNA]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSG1 mRNA; Hydrocortisone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSG1 mRNA]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of DSG1 mRNA] CTD PMID:32076005 NCBI chr18:11,674,687...11,705,383
Ensembl chr18:11,674,402...11,703,443
JBrowse link
G Dst dystonin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DST protein CTD PMID:28713220 NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
JBrowse link
G Duox1 dual oxidase 1 multiple interactions
decreases expression
ISO Antimony Potassium Tartrate inhibits the reaction [IL4 protein results in increased expression of DUOX1 mRNA]
Antimony Potassium Tartrate results in decreased expression of DUOX1 mRNA
CTD PMID:29031483 NCBI chr 3:109,260,526...109,295,588
Ensembl chr 3:109,262,397...109,295,563
JBrowse link
G Duoxa1 dual oxidase maturation factor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DUOXA1 mRNA CTD PMID:29031483 NCBI chr 3:109,249,815...109,260,511
Ensembl chr 3:109,249,923...109,260,499
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of DUSP1 mRNA CTD PMID:17547211 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Dusp12 dual specificity phosphatase 12 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP12 mRNA] CTD PMID:28713220 NCBI chr13:83,122,192...83,131,800
Ensembl chr13:83,122,193...83,131,285
JBrowse link
G Dusp2 dual specificity phosphatase 2 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP2 mRNA] CTD PMID:28713220 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
JBrowse link
G Egr3 early growth response 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of EGR3 mRNA CTD PMID:32076005 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627
JBrowse link
G Ehf ets homologous factor multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of EHF mRNA CTD PMID:32076005 NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997
JBrowse link
G Elf3 E74 like ETS transcription factor 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of ELF3 mRNA CTD PMID:32076005 NCBI chr13:46,690,460...46,695,394
Ensembl chr13:46,690,466...46,695,481
JBrowse link
G Epha1 Eph receptor A1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of EPHA1 protein CTD PMID:32076005 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846
JBrowse link
G Epha2 Eph receptor A2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of EPHA2 protein CTD PMID:32076005 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117
JBrowse link
G Ephx1 epoxide hydrolase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 NCBI chr13:92,714,315...92,744,124
Ensembl chr13:92,714,315...92,790,235
JBrowse link
G F5 coagulation factor V decreases expression ISO Antimony Potassium Tartrate results in decreased expression of F5 mRNA CTD PMID:17547211 NCBI chr13:76,513,463...76,583,106
Ensembl chr13:76,513,255...76,582,317
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FABP5 mRNA CTD PMID:28713220 NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FDFT1 mRNA CTD PMID:17547211 NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FDPS mRNA CTD PMID:17547211 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FGFR3 mRNA CTD PMID:32076005 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341
JBrowse link
G Flg filaggrin decreases expression
multiple interactions
ISO Antimony Potassium Tartrate results in decreased expression of FLG mRNA
2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FLG mRNA]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FLG mRNA; Hydrocortisone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FLG mRNA]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FLG mRNA]
CTD PMID:28713220 PMID:32076005 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FOS mRNA CTD PMID:32076005 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Antimony Potassium Tartrate results in increased expression of FOSL1 mRNA CTD PMID:17547211 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxq1 forkhead box Q1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of FOXQ1 mRNA CTD PMID:32076005 NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of FTH1 mRNA; Antimony Potassium Tartrate results in increased expression of FTH1 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of FTH1 mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
JBrowse link
G Ftl1 ferritin light chain 1 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of FTL mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of FTL mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of G6PD mRNA; Antimony Potassium Tartrate results in increased expression of G6PD protein CTD PMID:28713220 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of GAPDH mRNA CTD PMID:28713220 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of GCLC mRNA; Antimony Potassium Tartrate results in increased expression of GCLC protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GCLC mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of GCLM mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GCLM mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Antimony Potassium Tartrate results in increased expression of GCNT3 mRNA CTD PMID:17547211 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562
JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GGT1 mRNA CTD PMID:32076005 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of GHITM mRNA CTD PMID:17547211 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879
JBrowse link
G Gla galactosidase, alpha increases expression ISO Antimony Potassium Tartrate results in increased expression of GLA mRNA CTD PMID:17547211 NCBI chr  X:97,769,227...97,780,646
Ensembl chr  X:97,768,996...97,780,664
JBrowse link
G Glrx glutaredoxin multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GLRX mRNA CTD PMID:32076005 NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GPX2 mRNA CTD PMID:32076005 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of GRHL1 mRNA CTD PMID:32076005 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301
JBrowse link
G Gsto1 glutathione S-transferase omega 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of GSTO1 mRNA CTD PMID:32076005 NCBI chr 1:246,721,089...246,731,228
Ensembl chr 1:246,721,221...246,731,468
JBrowse link
G Gtpbp6 GTP binding protein 6 (putative) increases expression ISO Antimony Potassium Tartrate results in increased expression of GTPBP6 mRNA CTD PMID:17547211 NCBI chr12:46,574,913...46,578,873
Ensembl chr12:46,574,435...46,578,873
JBrowse link
G H4c3 H4 clustered histone 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of H4C3 mRNA CTD PMID:17547211
G Hltf helicase-like transcription factor multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HLTF mRNA CTD PMID:32076005 NCBI chr 2:102,549,724...102,609,492
Ensembl chr 2:102,549,724...102,609,327
JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of HMGA1 mRNA CTD PMID:17547211 NCBI chr20:5,611,088...5,618,755
Ensembl chr20:5,611,694...5,618,752
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of HMOX1 mRNA; Antimony Potassium Tartrate results in increased expression of HMOX1 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HMOX1 mRNA
CTD PMID:17547211 PMID:28713220 PMID:32076005 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hopx HOP homeobox multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of HOPX mRNA CTD PMID:32076005 NCBI chr14:31,055,912...31,082,909
Ensembl chr14:31,075,148...31,082,909
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of HSD17B2 mRNA CTD PMID:17547211 NCBI chr19:45,753,576...45,825,203
Ensembl chr19:45,753,574...45,825,202
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of HSD17B7 mRNA CTD PMID:17547211 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HSPA1A mRNA CTD PMID:32076005
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HSPA8 mRNA CTD PMID:32076005 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HSPB8 mRNA CTD PMID:32076005 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Htatip2 HIV-1 Tat interactive protein 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of HTATIP2 mRNA CTD PMID:32076005 NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of ID1 mRNA CTD PMID:32076005 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Ier2 immediate early response 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of IER2 mRNA CTD PMID:17547211 NCBI chr19:23,494,551...23,496,075
Ensembl chr19:23,494,184...23,499,211
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of IFRD1 mRNA CTD PMID:17547211 NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990
JBrowse link
G Ikzf2 IKAROS family zinc finger 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of IKZF2 mRNA CTD PMID:32076005 NCBI chr 9:71,042,440...71,191,296
Ensembl chr 9:71,042,440...71,190,867
JBrowse link
G Il1rn interleukin 1 receptor antagonist multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of IL1RN mRNA CTD PMID:32076005 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [IL4 protein results in increased expression of DUOX1 mRNA] CTD PMID:29031483 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Ing3 inhibitor of growth family, member 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of ING3 mRNA CTD PMID:17547211 NCBI chr 4:50,477,954...50,505,168
Ensembl chr 4:50,477,962...50,503,715
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein increases expression ISO Antimony Potassium Tartrate results in increased expression of ITGB3BP mRNA CTD PMID:17547211 NCBI chr 5:114,460,217...114,525,538
Ensembl chr 5:114,460,221...114,525,704
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ITIH3 mRNA CTD PMID:17547211 NCBI chr16:6,101,922...6,117,154
Ensembl chr16:6,101,930...6,116,924
JBrowse link
G Ivl involucrin decreases expression
multiple interactions
ISO Antimony Potassium Tartrate results in decreased expression of IVL mRNA; Antimony Potassium Tartrate results in decreased expression of IVL protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of IVL mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Klf5 Kruppel-like factor 5 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KLF5 mRNA CTD PMID:32076005 NCBI chr15:76,060,320...76,079,445
Ensembl chr15:76,064,258...76,079,445
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression ISO Antimony Potassium Tartrate results in increased expression of KLF6 mRNA CTD PMID:17547211 NCBI chr17:64,539,456...64,548,451
Ensembl chr17:64,531,463...64,588,570
JBrowse link
G Krt1 keratin 1 multiple interactions ISO 2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT1 mRNA]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT1 mRNA; Hydrocortisone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT1 mRNA]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT1 mRNA] CTD PMID:32076005 NCBI chr 7:132,976,618...132,981,844
Ensembl chr 7:132,976,620...132,981,844
JBrowse link
G Krt10 keratin 10 decreases expression
multiple interactions
ISO Antimony Potassium Tartrate results in decreased expression of KRT10 mRNA; Antimony Potassium Tartrate results in decreased expression of KRT10 protein
2-tert-butyl-9-fluoro-3,6-dihydro-7H-benz(h)imidazo(4,5-f)isoquinoline-7-one promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT10 mRNA]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT10 mRNA; Hydrocortisone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT10 mRNA]; U 0126 inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of KRT10 mRNA]
CTD PMID:28713220 PMID:32076005 NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
JBrowse link
G Krtdap keratinocyte differentiation associated protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of KRTDAP mRNA CTD PMID:28713220 NCBI chr 1:86,038,296...86,041,594
Ensembl chr 1:86,038,437...86,041,455
JBrowse link
G Lipa lipase A, lysosomal acid type decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LIPA mRNA CTD PMID:17547211 NCBI chr 1:232,024,351...232,167,329
Ensembl chr 1:232,024,356...232,057,633
JBrowse link
G Loricrin loricrin cornified envelope precursor protein multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of LORICRIN mRNA CTD PMID:32076005 NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807
JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LRIG1 mRNA CTD PMID:28713220 NCBI chr 4:127,130,899...127,230,956
Ensembl chr 4:127,130,898...127,231,513
JBrowse link
G Lss lanosterol synthase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LSS mRNA CTD PMID:17547211 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Antimony Potassium Tartrate results in increased expression of MAFF mRNA CTD PMID:17547211 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Man1a2 mannosidase, alpha, class 1A, member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of MAN1A2 mRNA CTD PMID:17547211 NCBI chr 2:187,947,484...188,096,332
Ensembl chr 2:187,951,617...188,096,332
JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of MAOA mRNA CTD PMID:32076005 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of MAP2K1 mRNA CTD PMID:32076005 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP
ISO
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of MAPK1 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased phosphorylation of MAPK1 protein
CTD PMID:32076005 PMID:32920012 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of MAPK3 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased phosphorylation of MAPK3 protein
CTD PMID:32076005 PMID:32920012 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of MCM2 mRNA CTD PMID:17547211 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of ME1 mRNA CTD PMID:28713220 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of MGAT2 mRNA CTD PMID:17547211 NCBI chr 6:87,656,360...87,658,849
Ensembl chr 6:87,656,349...87,658,177
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of MGST1 mRNA CTD PMID:32076005 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Antimony Potassium Tartrate results in increased expression of MT2A mRNA CTD PMID:28713220 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance
ISO [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Antimony Potassium Tartrate
MYCN protein results in decreased susceptibility to Antimony Potassium Tartrate
CTD PMID:10348353 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Ndrg2 NDRG family member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NDRG2 mRNA CTD PMID:17547211 NCBI chr15:24,600,981...24,609,621
Ensembl chr15:24,600,982...24,609,626
JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of NFKB2 mRNA CTD PMID:32076005 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NFKBIA mRNA CTD PMID:17547211 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nkx3-1 NK3 homeobox 1 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of NKX3-1 mRNA; Antimony Potassium Tartrate results in increased expression of NKX3-1 protein
bicalutamide inhibits the reaction [Antimony Potassium Tartrate results in increased expression of NKX3-1 mRNA]
CTD PMID:29462692 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of NQO1 mRNA; Antimony Potassium Tartrate results in increased expression of NQO1 protein
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of NQO1 mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of NQO2 mRNA CTD PMID:28713220 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NR0B2 mRNA CTD PMID:17547211 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
JBrowse link
G Os9 OS9, endoplasmic reticulum lectin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of OS9 mRNA CTD PMID:17547211 NCBI chr 7:62,915,498...62,957,591
Ensembl chr 7:62,915,515...62,943,745
JBrowse link
G Osm oncostatin M multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] inhibits the reaction [OSM protein results in increased phosphorylation of STAT1 protein] CTD PMID:32076005 NCBI chr14:79,103,638...79,108,500
Ensembl chr14:79,104,344...79,108,313
JBrowse link
G Pbx1 PBX homeobox 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of PBX1 mRNA CTD PMID:32076005 NCBI chr13:80,278,766...80,588,563
Ensembl chr13:80,278,770...80,588,594
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PDIA4 mRNA CTD PMID:17547211 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107
JBrowse link
G Pgc progastricsin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PGC mRNA CTD PMID:17547211 NCBI chr 9:13,257,462...13,265,682
Ensembl chr 9:13,257,462...13,265,682
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of PGD protein CTD PMID:28713220 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of PGM1 mRNA CTD PMID:28713220 NCBI chr 5:114,595,298...114,654,728
Ensembl chr 5:114,595,293...114,654,728
JBrowse link
G Pgm3 phosphoglucomutase 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of PGM3 mRNA CTD PMID:28713220 NCBI chr 8:87,517,931...87,536,034
Ensembl chr 8:87,517,701...87,536,022
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of PIK3R1 mRNA CTD PMID:32076005 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pik3r2 phosphoinositide-3-kinase regulatory subunit 2 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of PIK3R2 mRNA CTD PMID:32076005 NCBI chr16:18,665,517...18,674,067
Ensembl chr16:18,665,457...18,674,065
JBrowse link
G Pir pirin multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of PIR mRNA CTD PMID:32076005 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218
JBrowse link
G Pitx1 paired-like homeodomain 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of PITX1 mRNA CTD PMID:32076005 NCBI chr17:8,794,134...8,800,292
Ensembl chr17:8,794,134...8,800,291
JBrowse link
G Pml PML nuclear body scaffold affects localization
multiple interactions
increases degradation
ISO Antimony Potassium Tartrate affects the localization of PML protein
Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein]
Antimony Potassium Tartrate results in increased degradation of PML protein mutant form
CTD PMID:9834237 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Ppih peptidylprolyl isomerase H increases expression ISO Antimony Potassium Tartrate results in increased expression of PPIH mRNA CTD PMID:17547211 NCBI chr 5:132,906,324...132,924,341
Ensembl chr 5:132,906,328...132,924,267
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of PRDX1 mRNA CTD PMID:32076005 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Psph phosphoserine phosphatase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PSPH mRNA CTD PMID:17547211 NCBI chr12:26,882,524...26,905,084
Ensembl chr12:26,883,133...26,905,074
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression ISO Antimony Potassium Tartrate results in increased expression of PTTG1 mRNA CTD PMID:17547211 NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837
JBrowse link
G Rara retinoic acid receptor, alpha increases degradation ISO Antimony Potassium Tartrate results in increased degradation of RARA protein mutant form CTD PMID:9834237 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Antimony Potassium Tartrate results in increased expression of RBPMS mRNA CTD PMID:17547211 NCBI chr16:58,239,370...58,395,424
Ensembl chr16:58,239,474...58,395,426
JBrowse link
G Rfc2 replication factor C subunit 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of RFC2 mRNA CTD PMID:17547211 NCBI chr12:22,120,449...22,133,576
Ensembl chr12:22,120,010...22,133,557
JBrowse link
G Rnaseh2a ribonuclease H2, subunit A increases expression ISO Antimony Potassium Tartrate results in increased expression of RNASEH2A mRNA CTD PMID:17547211 NCBI chr19:23,186,325...23,196,045
Ensembl chr19:23,186,383...23,196,041
JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RNH1 protein CTD PMID:28713220 NCBI chr 1:196,269,293...196,281,763
Ensembl chr 1:196,269,293...196,281,910
JBrowse link
G Rptn repetin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RPTN mRNA CTD PMID:28713220 NCBI chr 2:179,061,768...179,066,056
Ensembl chr 2:179,060,017...179,065,910
JBrowse link
G Ryr1 ryanodine receptor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RYR1 mRNA CTD PMID:28713220 NCBI chr 1:84,292,578...84,423,799
Ensembl chr 1:84,292,578...84,423,812
JBrowse link
G S100a2 S100 calcium binding protein A2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A2 mRNA CTD PMID:28713220 NCBI chr 2:176,075,060...176,078,782 JBrowse link
G S100a8 S100 calcium binding protein A8 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A8 mRNA; Antimony Potassium Tartrate results in decreased expression of S100A8 protein CTD PMID:28713220 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A9 mRNA; Antimony Potassium Tartrate results in decreased expression of S100A9 protein CTD PMID:28713220 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SCD mRNA CTD PMID:17547211 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sephs2 selenophosphate synthetase 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SEPHS2 mRNA CTD PMID:17547211 NCBI chr 1:181,893,146...181,895,464
Ensembl chr 1:181,892,599...181,895,497
JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SERPINB1 mRNA CTD PMID:17547211 NCBI chr17:31,590,695...31,599,102
Ensembl chr17:31,590,677...31,599,102
JBrowse link
G Serpinc1 serpin family C member 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SERPINC1 mRNA CTD PMID:17547211 NCBI chr13:73,257,208...73,271,476
Ensembl chr13:73,257,179...73,284,293
JBrowse link
G Serpine1 serpin family E member 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SERPINE1 mRNA CTD PMID:32076005 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of SIK1 mRNA CTD PMID:17547211 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Slc2a3 solute carrier family 2 member 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SLC2A3 mRNA CTD PMID:32076005 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472
JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Antimony Potassium Tartrate results in increased expression of SNRPA mRNA CTD PMID:17547211 NCBI chr 1:82,481,770...82,490,540
Ensembl chr 1:82,481,770...82,490,538
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SOD1 mRNA CTD PMID:32076005 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sprr1a small proline-rich protein 1A decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR1A mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR1A protein CTD PMID:28713220 NCBI chr 2:178,055,096...178,057,012
Ensembl chr 2:178,055,096...178,057,063
JBrowse link
G Sprr1b small proline-rich protein 1B decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR1B mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR1B protein CTD PMID:28713220 NCBI chr 2:178,009,130...178,009,567
Ensembl chr 2:178,009,130...178,009,567
JBrowse link
G Sprr3 small proline-rich protein 3 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR3 mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR3 protein CTD PMID:28713220 NCBI chr 2:178,027,743...178,028,501
Ensembl chr 2:178,027,425...178,029,891
JBrowse link
G Sqle squalene epoxidase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SQLE mRNA CTD PMID:17547211 NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SQSTM1 mRNA CTD PMID:32076005 NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SRSF1 mRNA CTD PMID:17547211 NCBI chr10:72,838,926...72,859,066
Ensembl chr10:72,839,274...72,845,336
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SRSF5 mRNA CTD PMID:17547211 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of SRXN1 mRNA CTD PMID:28713220 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ST6GALNAC4 mRNA CTD PMID:17547211 NCBI chr 3:15,872,230...15,885,250
Ensembl chr 3:15,872,532...15,885,243
JBrowse link
G Stat1 signal transducer and activator of transcription 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] inhibits the reaction [OSM protein results in increased phosphorylation of STAT1 protein]; [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of STAT1 mRNA CTD PMID:32076005 NCBI chr 9:49,419,561...49,459,969 JBrowse link
G Sult1c3 sulfotransferase family 1C member 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of SULT1C3 mRNA CTD PMID:32076005 NCBI chr 9:7,221,580...7,266,991
Ensembl chr 9:7,221,578...7,267,030
JBrowse link
G Sult1e1 sulfotransferase family 1E member 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of SULT1E1 mRNA CTD PMID:32076005 NCBI chr14:20,422,324...20,439,562
Ensembl chr14:20,422,324...20,439,275
JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of SULT2B1 mRNA CTD PMID:32076005 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects localization
multiple interactions
ISO Antimony Potassium Tartrate affects the localization of SUMO1 protein
Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein]
CTD PMID:9834237 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761
JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TARDBP mRNA CTD PMID:17547211 NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055
JBrowse link
G Tgm1 transglutaminase 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of TGM1 mRNA CTD PMID:32076005 NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of TNFAIP3 mRNA CTD PMID:17547211 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TNFSF10 mRNA CTD PMID:17547211 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tob1 transducer of ErbB-2.1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TOB1 mRNA CTD PMID:17547211 NCBI chr10:79,163,093...79,165,131
Ensembl chr10:79,160,154...79,165,215
JBrowse link
G Tp63 tumor protein p63 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of TP63 mRNA CTD PMID:32076005 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TPI1 mRNA CTD PMID:28713220 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541
JBrowse link
G Tsc22d3 TSC22 domain family, member 3 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in decreased expression of TSC22D3 mRNA CTD PMID:32076005 NCBI chr  X:104,217,898...104,277,935
Ensembl chr  X:104,217,925...104,276,861
JBrowse link
G Tspan7 tetraspanin 7 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TSPAN7 mRNA CTD PMID:17547211 NCBI chr  X:12,208,783...12,306,160
Ensembl chr  X:12,208,783...12,306,131
JBrowse link
G Tuft1 tuftelin 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TUFT1 mRNA CTD PMID:17547211 NCBI chr 2:182,259,457...182,306,296
Ensembl chr 2:182,260,398...182,306,192
JBrowse link
G Txn1 thioredoxin 1 multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of TXN mRNA CTD PMID:32076005 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of TXNRD1 mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of TXNRD1 mRNA
CTD PMID:17547211 PMID:28713220 PMID:32076005 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Tyms thymidylate synthetase increases expression ISO Antimony Potassium Tartrate results in increased expression of TYMS mRNA CTD PMID:17547211 NCBI chr 9:113,313,454...113,329,551
Ensembl chr 9:113,313,452...113,329,536
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression ISO Antimony Potassium Tartrate results in increased expression of UBE2C mRNA CTD PMID:17547211 NCBI chr 3:153,506,636...153,509,036
Ensembl chr 3:153,506,636...153,513,339
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of UGT1A6 mRNA
[Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of UGT1A6 mRNA
CTD PMID:28713220 PMID:32076005 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Zwint ZW10 interacting kinetochore protein increases expression ISO Antimony Potassium Tartrate results in increased expression of ZWINT mRNA CTD PMID:17547211 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link
hycanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Hycanthone results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
lucanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca12 ATP binding cassette subfamily A member 12 increases expression ISO Lucanthone results in increased expression of ABCA12 mRNA CTD PMID:21148553 NCBI chr 9:72,822,661...72,995,748
Ensembl chr 9:72,823,350...72,996,049
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression ISO Lucanthone results in increased expression of ACTA2 mRNA CTD PMID:21148553 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 decreases expression ISO Lucanthone results in decreased expression of ALDH1L2 mRNA CTD PMID:21148553 NCBI chr 7:20,254,196...20,305,793
Ensembl chr 7:20,254,233...20,305,776
JBrowse link
G Anln anillin, actin binding protein decreases expression ISO Lucanthone results in decreased expression of ANLN mRNA CTD PMID:21148553 NCBI chr 8:20,858,227...20,921,602
Ensembl chr 8:20,858,228...20,921,538
JBrowse link
G Anxa3 annexin A3 decreases expression ISO Lucanthone results in decreased expression of ANXA3 mRNA CTD PMID:21148553 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) increases expression ISO Lucanthone results in increased expression of AQP3 mRNA CTD PMID:21148553 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720
JBrowse link
G Arhgap11a Rho GTPase activating protein 11A decreases expression ISO Lucanthone results in decreased expression of ARHGAP11A mRNA CTD PMID:21148553 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Lucanthone results in decreased expression of ASNS mRNA CTD PMID:21148553 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Aspm assembly factor for spindle microtubules decreases expression ISO Lucanthone results in decreased expression of ASPM mRNA CTD PMID:21148553 NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
JBrowse link
G Atad2 ATPase family, AAA domain containing 2 decreases expression ISO Lucanthone results in decreased expression of ATAD2 mRNA CTD PMID:21148553 NCBI chr 7:89,634,123...89,676,738
Ensembl chr 7:89,634,123...89,676,738
JBrowse link
G Aurka aurora kinase A decreases expression ISO Lucanthone results in decreased expression of AURKA mRNA CTD PMID:21148553 NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
JBrowse link
G Aurkb aurora kinase B decreases expression ISO Lucanthone results in decreased expression of AURKB mRNA CTD PMID:21148553 NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Lucanthone results in decreased expression of BIRC5 mRNA CTD PMID:21148553 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blm BLM RecQ like helicase decreases expression ISO Lucanthone results in decreased expression of BLM mRNA CTD PMID:21148553 NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
JBrowse link
G Brca1 BRCA1, DNA repair associated decreases expression ISO Lucanthone results in decreased expression of BRCA1 mRNA CTD PMID:21148553 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Brca2 BRCA2, DNA repair associated decreases expression ISO Lucanthone results in decreased expression of BRCA2 mRNA CTD PMID:21148553 NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO Lucanthone results in decreased expression of BUB1 mRNA CTD PMID:21148553 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B decreases expression ISO Lucanthone results in decreased expression of BUB1B mRNA CTD PMID:21148553 NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
JBrowse link
G Ccn3 cellular communication network factor 3 increases expression ISO Lucanthone results in increased expression of CCN3 mRNA CTD PMID:21148553 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019
JBrowse link
G Ccna2 cyclin A2 decreases expression ISO Lucanthone results in decreased expression of CCNA2 mRNA CTD PMID:21148553 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnb1 cyclin B1 decreases expression ISO Lucanthone results in decreased expression of CCNB1 mRNA CTD PMID:21148553 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Lucanthone results in decreased expression of CCNB2 mRNA CTD PMID:21148553 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874
JBrowse link
G Cdc20 cell division cycle 20 decreases expression ISO Lucanthone results in decreased expression of CDC20 mRNA CTD PMID:21148553 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdc25c cell division cycle 25C decreases expression ISO Lucanthone results in decreased expression of CDC25C mRNA CTD PMID:21148553 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdc45 cell division cycle 45 decreases expression ISO Lucanthone results in decreased expression of CDC45 mRNA CTD PMID:21148553 NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
JBrowse link
G Cdc6 cell division cycle 6 decreases expression ISO Lucanthone results in decreased expression of CDC6 mRNA CTD PMID:21148553 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
JBrowse link
G Cdca2 cell division cycle associated 2 decreases expression ISO Lucanthone results in decreased expression of CDCA2 mRNA CTD PMID:21148553 NCBI chr15:41,895,946...41,942,226
Ensembl chr15:41,895,901...41,941,611
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO Lucanthone results in decreased expression of CDK1 mRNA CTD PMID:21148553 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Lucanthone results in increased expression of CDKN1A mRNA CTD PMID:21148553 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO Lucanthone results in decreased expression of CDKN3 mRNA CTD PMID:21148553 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
JBrowse link
G Cenpa centromere protein A decreases expression ISO Lucanthone results in decreased expression of CENPA mRNA CTD PMID:21148553 NCBI chr 6:25,700,142...25,711,767
Ensembl chr 6:25,700,142...25,711,675
JBrowse link
G Cenpe centromere protein E decreases expression ISO Lucanthone results in decreased expression of CENPE mRNA CTD PMID:21148553 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cenpf centromere protein F decreases expression ISO Lucanthone results in decreased expression of CENPF mRNA CTD PMID:21148553 NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
JBrowse link
G Cenpi centromere protein I decreases expression ISO Lucanthone results in decreased expression of CENPI mRNA CTD PMID:21148553 NCBI chr  X:97,515,919...97,567,671
Ensembl chr  X:97,515,972...97,567,657
JBrowse link
G Cenpk centromere protein K decreases expression ISO Lucanthone results in decreased expression of CENPK mRNA CTD PMID:21148553 NCBI chr 2:35,360,132...35,421,372
Ensembl chr 2:35,360,132...35,385,706
JBrowse link
G Cenpl centromere protein L decreases expression ISO Lucanthone results in decreased expression of CENPL mRNA CTD PMID:21148553 NCBI chr13:73,337,235...73,352,115
Ensembl chr13:73,337,257...73,352,114
JBrowse link
G Cenpu centromere protein U decreases expression ISO Lucanthone results in decreased expression of CENPU mRNA CTD PMID:21148553 NCBI chr16:45,715,821...45,739,038
Ensembl chr16:45,714,294...45,738,823
JBrowse link
G Cep55 centrosomal protein 55 decreases expression ISO Lucanthone results in decreased expression of CEP55 mRNA CTD PMID:21148553 NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
JBrowse link
G Cip2a cellular inhibitor of PP2A decreases expression ISO Lucanthone results in decreased expression of CIP2A mRNA CTD PMID:21148553 NCBI chr11:51,792,143...51,823,016
Ensembl chr11:51,795,024...51,822,938
JBrowse link
G Cit citron rho-interacting serine/threonine kinase decreases expression ISO Lucanthone results in decreased expression of CIT mRNA CTD PMID:21148553 NCBI chr12:40,603,073...40,764,846
Ensembl chr12:40,605,563...40,763,860
JBrowse link
G Ckap2l cytoskeleton associated protein 2-like decreases expression ISO Lucanthone results in decreased expression of CKAP2L mRNA CTD PMID:21148553 NCBI chr 3:116,497,186...116,524,302
Ensembl chr 3:116,498,022...116,524,366
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B decreases expression ISO Lucanthone results in decreased expression of CKS1B mRNA CTD PMID:21148553 NCBI chr 2:174,833,025...174,837,614
Ensembl chr 2:174,833,050...174,837,636
JBrowse link
G Clca2 chloride channel accessory 2 increases expression ISO Lucanthone results in increased expression of CLCA2 mRNA CTD PMID:21148553 NCBI chr 2:233,993,619...234,022,691
Ensembl chr 2:233,995,078...234,022,199
JBrowse link
G Cldn1 claudin 1 decreases expression ISO Lucanthone results in decreased expression of CLDN1 mRNA CTD PMID:21148553 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Clgn calmegin decreases expression ISO Lucanthone results in decreased expression of CLGN mRNA CTD PMID:21148553 NCBI chr19:24,695,140...24,728,542
Ensembl chr19:24,696,875...24,728,758
JBrowse link
G Cmklr2 chemerin chemokine-like receptor 2 decreases expression ISO Lucanthone results in decreased expression of CMKLR2 mRNA CTD PMID:21148553 NCBI chr 9:64,583,310...64,618,127
Ensembl chr 9:64,585,594...64,586,655
JBrowse link
G Ctsd cathepsin D increases expression ISO Lucanthone results in increased expression of CTSD mRNA; Lucanthone results in increased expression of CTSD protein CTD PMID:21148553 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression ISO Lucanthone results in increased expression of CXCL10 mRNA CTD PMID:21148553 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO Lucanthone results in increased expression of CYP1A1 mRNA CTD PMID:21148553 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 decreases expression ISO Lucanthone results in decreased expression of DDIT3 mRNA CTD PMID:21148553 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Depdc1 DEP domain containing 1 decreases expression ISO Lucanthone results in decreased expression of DEPDC1 mRNA CTD PMID:21148553 NCBI chr 2:248,684,508...248,717,951
Ensembl chr 2:248,684,523...248,717,951
JBrowse link
G Depdc1b DEP domain containing 1B decreases expression ISO Lucanthone results in decreased expression of DEPDC1B mRNA CTD PMID:21148553 NCBI chr 2:39,891,163...39,963,779
Ensembl chr 2:39,891,481...39,963,779
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Lucanthone results in increased expression of DHCR24 mRNA CTD PMID:21148553 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Diaph3 diaphanous-related formin 3 decreases expression ISO Lucanthone results in decreased expression of DIAPH3 mRNA CTD PMID:21148553 NCBI chr15:62,543,375...63,013,060
Ensembl chr15:62,543,375...63,012,975
JBrowse link
G Dlgap5 DLG associated protein 5 decreases expression ISO Lucanthone results in decreased expression of DLGAP5 mRNA CTD PMID:21148553 NCBI chr15:20,633,964...20,664,569
Ensembl chr15:20,633,966...20,664,518
JBrowse link
G Dna2 DNA replication helicase/nuclease 2 decreases expression ISO Lucanthone results in decreased expression of DNA2 mRNA CTD PMID:21148553 NCBI chr20:25,661,652...25,690,598 JBrowse link
G Dnai3 dynein axonemal intermediate chain 3 increases expression ISO Lucanthone results in increased expression of DNAI3 mRNA CTD PMID:21148553 NCBI chr 2:234,947,910...235,006,173
Ensembl chr 2:234,929,677...235,006,173
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO Lucanthone results in increased expression of DPP4 mRNA CTD PMID:21148553 NCBI chr 3:46,962,243...47,043,870
Ensembl chr 3:46,962,243...47,043,901
JBrowse link
G Dtl denticleless E3 ubiquitin protein ligase homolog decreases expression ISO Lucanthone results in decreased expression of DTL mRNA CTD PMID:21148553 NCBI chr13:103,115,810...103,155,029
Ensembl chr13:103,117,186...103,154,890
JBrowse link
G Ect2 epithelial cell transforming 2 decreases expression ISO Lucanthone results in decreased expression of ECT2 mRNA CTD PMID:21148553 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO Lucanthone results in decreased expression of EFEMP1 mRNA CTD PMID:21148553 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Ercc6l ERCC excision repair 6 like, spindle assembly checkpoint helicase decreases expression ISO Lucanthone results in decreased expression of ERCC6L mRNA CTD PMID:21148553 NCBI chr  X:67,245,414...67,261,222
Ensembl chr  X:67,245,414...67,280,756
JBrowse link
G Esco2 establishment of sister chromatid cohesion N-acetyltransferase 2 decreases expression ISO Lucanthone results in decreased expression of ESCO2 mRNA CTD PMID:21148553 NCBI chr15:40,034,566...40,052,295
Ensembl chr15:40,034,568...40,055,306
JBrowse link
G Espl1 extra spindle pole bodies like 1, separase decreases expression ISO Lucanthone results in decreased expression of ESPL1 mRNA CTD PMID:21148553 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
JBrowse link
G Exo1 exonuclease 1 decreases expression ISO Lucanthone results in decreased expression of EXO1 mRNA CTD PMID:21148553 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Exosc8 exosome component 8 decreases expression ISO Lucanthone results in decreased expression of EXOSC8 mRNA CTD PMID:21148553 NCBI chr 2:138,930,405...138,937,009
Ensembl chr 2:138,930,405...138,936,928
JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit decreases expression ISO Lucanthone results in decreased expression of EZH2 mRNA CTD PMID:21148553 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362
JBrowse link
G Fam72a family with sequence similarity 72, member A decreases expression ISO Lucanthone results in decreased expression of FAM72A mRNA CTD PMID:21148553 NCBI chr13:42,968,409...42,978,976
Ensembl chr13:42,967,578...42,984,208
JBrowse link
G Fanci FA complementation group I decreases expression ISO Lucanthone results in decreased expression of FANCI mRNA CTD PMID:21148553 NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
JBrowse link
G Fbxo5 F-box protein 5 decreases expression ISO Lucanthone results in decreased expression of FBXO5 mRNA CTD PMID:21148553 NCBI chr 1:42,196,068...42,202,437
Ensembl chr 1:42,196,068...42,202,437
JBrowse link
G Flg filaggrin decreases expression ISO Lucanthone results in decreased expression of FLG mRNA CTD PMID:21148553 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Foxm1 forkhead box M1 decreases expression ISO Lucanthone results in decreased expression of FOXM1 mRNA CTD PMID:21148553 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Gbp1 guanylate binding protein 1 decreases expression ISO Lucanthone results in decreased expression of GBP1 mRNA CTD PMID:21148553 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,517,398...231,529,600
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Lucanthone results in increased expression of GDF15 mRNA CTD PMID:21148553 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gpnmb glycoprotein nmb increases expression ISO Lucanthone results in increased expression of GPNMB mRNA CTD PMID:21148553 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367
JBrowse link
G Gpx8 glutathione peroxidase 8 decreases expression ISO Lucanthone results in decreased expression of GPX8 mRNA CTD PMID:21148553 NCBI chr 2:44,676,448...44,680,042
Ensembl chr 2:44,676,454...44,680,195
JBrowse link
G Gtpbp2 GTP binding protein 2 decreases expression ISO Lucanthone results in decreased expression of GTPBP2 mRNA CTD PMID:21148553 NCBI chr 9:14,813,964...14,823,419
Ensembl chr 9:14,813,964...14,823,241
JBrowse link
G H1f4 H1.4 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-4 mRNA CTD PMID:21148553 NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G H1f5 H1.5 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-5 mRNA CTD PMID:21148553 NCBI chr17:42,726,189...42,726,857
Ensembl chr17:42,726,127...42,769,160
JBrowse link
G H2ac12 H2A clustered histone 12 decreases expression ISO Lucanthone results in decreased expression of H2AC12 mRNA CTD PMID:21148553 NCBI chr17:42,486,315...42,486,880 JBrowse link
G H2ac21 H2A clustered histone 21 decreases expression ISO Lucanthone results in decreased expression of H2AC21 mRNA CTD PMID:21148553 NCBI chr 2:183,779,385...183,779,777 JBrowse link
G H2ac4 H2A clustered histone 4 decreases expression ISO Lucanthone results in decreased expression of H2AC4 mRNA CTD PMID:21148553 NCBI chr17:42,799,953...42,800,345
Ensembl chr17:42,799,652...42,800,381
JBrowse link
G H2bc9 H2B clustered histone 9 decreases expression ISO Lucanthone results in decreased expression of H2BC9 mRNA CTD PMID:21148553 NCBI chr17:42,470,593...42,478,605 JBrowse link
G H3c13 H3 clustered histone 13 decreases expression ISO Lucanthone results in decreased expression of H3C13 mRNA CTD PMID:21148553 NCBI chr17:41,529,860...41,532,577 JBrowse link
G H4c3 H4 clustered histone 3 decreases expression ISO Lucanthone results in decreased expression of H4C3 mRNA CTD PMID:21148553
G H4f3 H1.3 linker histone, cluster member decreases expression ISO Lucanthone results in decreased expression of H1-3 mRNA CTD PMID:21148553 NCBI chr17:41,528,576...41,554,586
Ensembl chr17:41,529,667...41,552,334
JBrowse link
G Hist1h2bl histone cluster 1 H2B family member l decreases expression ISO Lucanthone results in decreased expression of H2BC8 mRNA CTD PMID:21148553 NCBI chr17:42,708,646...42,709,435 JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression ISO Lucanthone results in decreased expression of H2BC7 mRNA CTD PMID:21148553 NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153
JBrowse link
G Hist1h3b histone cluster 1, H3b decreases expression ISO Lucanthone results in decreased expression of H3C12 mRNA CTD PMID:21148553 NCBI chr17:42,722,805...42,723,925 JBrowse link
G Hist2h4 histone cluster 2, H4 decreases expression ISO Lucanthone results in decreased expression of H4C2 mRNA CTD PMID:21148553 NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048
JBrowse link
G Hist2h4a histone cluster 2 H4 family member A decreases expression ISO Lucanthone results in decreased expression of H4C4 mRNA CTD PMID:21148553
G Hjurp Holliday junction recognition protein decreases expression ISO Lucanthone results in decreased expression of HJURP mRNA CTD PMID:21148553 NCBI chr 9:88,853,379...88,867,730
Ensembl chr 9:88,853,386...88,867,728
JBrowse link
G Hmgb2 high mobility group box 2 decreases expression ISO Lucanthone results in decreased expression of HMGB2 mRNA CTD PMID:21148553 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Lucanthone results in increased expression of HMGCS1 mRNA CTD PMID:21148553 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
JBrowse link
G Hmmr hyaluronan-mediated motility receptor decreases expression ISO Lucanthone results in decreased expression of HMMR mRNA CTD PMID:21148553 NCBI chr10:25,132,933...25,163,029
Ensembl chr10:25,132,977...25,163,060
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Lucanthone results in increased expression of ICAM1 mRNA CTD PMID:21148553 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO Lucanthone results in increased expression of IDI1 mRNA CTD PMID:21148553 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Ifi30 IFI30, lysosomal thiol reductase increases expression ISO Lucanthone results in increased expression of IFI30 mRNA CTD PMID:21148553 NCBI chr16:18,675,651...18,679,857
Ensembl chr16:18,675,613...18,681,175
JBrowse link
G Il18 interleukin 18 decreases expression ISO Lucanthone results in decreased expression of IL18 mRNA CTD PMID:21148553 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
JBrowse link
G Il24 interleukin 24 increases expression ISO Lucanthone results in increased expression of IL24 mRNA CTD PMID:21148553 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il6 interleukin 6 increases expression ISO Lucanthone results in increased expression of IL6 mRNA CTD PMID:21148553 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Iqgap3 IQ motif containing GTPase activating protein 3 decreases expression ISO Lucanthone results in decreased expression of IQGAP3 mRNA CTD PMID:21148553 NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956
JBrowse link
G Itga3 integrin subunit alpha 3 increases expression ISO Lucanthone results in increased expression of ITGA3 mRNA CTD PMID:21148553 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Kif11 kinesin family member 11 decreases expression ISO Lucanthone results in decreased expression of KIF11 mRNA CTD PMID:21148553 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Kif14 kinesin family member 14 decreases expression ISO Lucanthone results in decreased expression of KIF14 mRNA CTD PMID:21148553 NCBI chr13:47,926,975...47,990,598
Ensembl chr13:47,927,044...47,989,164
JBrowse link
G Kif15 kinesin family member 15 decreases expression ISO Lucanthone results in decreased expression of KIF15 mRNA CTD PMID:21148553 NCBI chr 8:122,601,888...122,672,750
Ensembl chr 8:122,601,897...122,672,750
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO Lucanthone results in decreased expression of KIF20A mRNA CTD PMID:21148553 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
JBrowse link
G Kif20b kinesin family member 20B decreases expression ISO Lucanthone results in decreased expression of KIF20B mRNA CTD PMID:21148553 NCBI chr 1:232,428,293...232,483,798
Ensembl chr 1:232,428,371...232,483,787
JBrowse link
G Kif22 kinesin family member 22 decreases expression ISO Lucanthone results in decreased expression of KIF22 mRNA CTD PMID:21148553 NCBI chr 1:181,635,347...181,650,351
Ensembl chr 1:181,635,183...181,650,401
JBrowse link
G Kif23 kinesin family member 23 decreases expression ISO Lucanthone results in decreased expression of KIF23 mRNA CTD PMID:21148553 NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
JBrowse link
G Kif2c kinesin family member 2C decreases expression ISO Lucanthone results in decreased expression of KIF2C mRNA CTD PMID:21148553 NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637
JBrowse link
G Kif4a kinesin family member 4A decreases expression ISO Lucanthone results in decreased expression of KIF4A mRNA CTD PMID:21148553 NCBI chr  X:65,721,724...65,824,151
Ensembl chr  X:65,721,779...65,824,139
JBrowse link
G Kifc1 kinesin family member C1 decreases expression ISO Lucanthone results in decreased expression of KIFC1 mRNA CTD PMID:21148553 NCBI chr20:4,998,832...5,017,107
Ensembl chr20:4,999,047...5,017,105
JBrowse link
G Knl1 kinetochore scaffold 1 decreases expression ISO Lucanthone results in decreased expression of KNL1 mRNA CTD PMID:21148553 NCBI chr 3:106,029,627...106,091,915
Ensembl chr 3:106,029,661...106,091,915
JBrowse link
G Lamp3 lysosomal-associated membrane protein 3 decreases expression ISO Lucanthone results in decreased expression of LAMP3 mRNA CTD PMID:21148553 NCBI chr11:81,153,491...81,224,643
Ensembl chr11:81,193,649...81,221,784
JBrowse link
G Lin9 lin-9 DREAM MuvB core complex component decreases expression ISO Lucanthone results in decreased expression of LIN9 mRNA CTD PMID:21148553 NCBI chr13:92,374,612...92,419,664
Ensembl chr13:92,374,593...92,419,654
JBrowse link
G LOC102551184 histone H4-like decreases expression ISO Lucanthone results in decreased expression of H4C12 mRNA CTD PMID:21148553 NCBI chr17:41,526,192...41,575,488 JBrowse link
G LOC690126 hypothetical protein LOC690126 decreases expression ISO Lucanthone results in decreased expression of H3C15 mRNA CTD PMID:21148553 NCBI chr 2:183,797,721...183,800,653 JBrowse link
G Lrp1 LDL receptor related protein 1 increases expression ISO Lucanthone results in increased expression of LRP1 mRNA CTD PMID:21148553 NCBI chr 7:63,380,325...63,461,029
Ensembl chr 7:63,380,356...63,460,910
JBrowse link
G Lxn latexin increases expression ISO Lucanthone results in increased expression of LXN mRNA CTD PMID:21148553 NCBI chr 2:151,727,556...151,733,426
Ensembl chr 2:151,727,102...151,733,460
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 decreases expression ISO Lucanthone results in decreased expression of MAD2L1 mRNA CTD PMID:21148553 NCBI chr 4:95,906,692...95,918,885
Ensembl chr 4:95,906,817...95,913,470
JBrowse link
G Mboat1 membrane bound O-acyltransferase domain containing 1 decreases expression ISO Lucanthone results in decreased expression of MBOAT1 mRNA CTD PMID:21148553 NCBI chr17:34,331,413...34,445,088
Ensembl chr17:34,331,422...34,445,088
JBrowse link
G Mcm10 minichromosome maintenance 10 replication initiation factor decreases expression ISO Lucanthone results in decreased expression of MCM10 mRNA CTD PMID:21148553 NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
JBrowse link
G Mcm8 minichromosome maintenance 8 homologous recombination repair factor decreases expression ISO Lucanthone results in decreased expression of MCM8 mRNA CTD PMID:21148553 NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008
JBrowse link
G Melk maternal embryonic leucine zipper kinase decreases expression ISO Lucanthone results in decreased expression of MELK mRNA CTD PMID:21148553 NCBI chr 5:58,540,393...58,600,937
Ensembl chr 5:58,540,449...58,600,937
JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Lucanthone results in decreased expression of MKI67 mRNA CTD PMID:21148553 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Lucanthone results in increased expression of MMP1 mRNA CTD PMID:21148553 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mnd1 meiotic nuclear divisions 1 decreases expression ISO Lucanthone results in decreased expression of MND1 mRNA CTD PMID:21148553 NCBI chr 2:169,433,538...169,496,081
Ensembl chr 2:169,433,540...169,496,096
JBrowse link
G Mocos molybdenum cofactor sulfurase decreases expression ISO Lucanthone results in decreased expression of MOCOS mRNA CTD PMID:21148553 NCBI chr18:15,931,654...15,977,415
Ensembl chr18:15,931,654...15,977,187
JBrowse link
G Msmo1 methylsterol monooxygenase 1 increases expression ISO Lucanthone results in increased expression of MSMO1 mRNA CTD PMID:21148553 NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
JBrowse link
G Mtfr2 mitochondrial fission regulator 2 decreases expression ISO Lucanthone results in decreased expression of MTFR2 mRNA CTD PMID:21148553 NCBI chr 1:15,123,232...15,138,632 JBrowse link
G Mx1 MX dynamin like GTPase 1 increases expression ISO Lucanthone results in increased expression of MX1 mRNA CTD PMID:21148553 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO Lucanthone results in decreased expression of MYBL2 mRNA CTD PMID:21148553 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
JBrowse link
G Ncapg non-SMC condensin I complex, subunit G decreases expression ISO Lucanthone results in decreased expression of NCAPG mRNA CTD PMID:21148553 NCBI chr14:65,404,235...65,432,902
Ensembl chr14:65,404,163...65,432,902
JBrowse link
G Ncapg2 non-SMC condensin II complex, subunit G2 decreases expression ISO Lucanthone results in decreased expression of NCAPG2 mRNA CTD PMID:21148553 NCBI chr 6:137,342,449...137,418,083
Ensembl chr 6:137,342,943...137,415,159
JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO Lucanthone results in decreased expression of NCAPH mRNA CTD PMID:21148553 NCBI chr 3:114,371,937...114,399,223
Ensembl chr 3:114,371,941...114,399,180
JBrowse link
G Ndc80 NDC80 kinetochore complex component decreases expression ISO Lucanthone results in decreased expression of NDC80 mRNA CTD PMID:21148553 NCBI chr 9:111,407,191...111,440,921
Ensembl chr 9:111,407,191...111,440,924
JBrowse link
G Nek2 NIMA-related kinase 2 decreases expression ISO Lucanthone results in decreased expression of NEK2 mRNA CTD PMID:21148553 NCBI chr13:103,405,818...103,419,063
Ensembl chr13:103,405,819...103,419,051
JBrowse link
G Nemp1 nuclear envelope integral membrane protein 1 decreases expression ISO Lucanthone results in decreased expression of NEMP1 mRNA CTD PMID:21148553 NCBI chr 7:63,514,025...63,538,791
Ensembl chr 7:63,479,951...63,534,602
JBrowse link
G Niban1 niban apoptosis regulator 1 decreases expression ISO Lucanthone results in decreased expression of NIBAN1 mRNA CTD PMID:21148553 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Lucanthone results in increased expression of NR4A2 mRNA CTD PMID:21148553 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex decreases expression ISO Lucanthone results in decreased expression of NUF2 mRNA CTD PMID:21148553 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO Lucanthone results in decreased expression of NUSAP1 mRNA CTD PMID:21148553 NCBI chr 3:106,603,273...106,633,624
Ensembl chr 3:106,603,289...106,633,624
JBrowse link
G Orc6 origin recognition complex, subunit 6 decreases expression ISO Lucanthone results in decreased expression of ORC6 mRNA CTD PMID:21148553 NCBI chr19:21,757,867...21,765,638
Ensembl chr19:21,757,866...21,765,662
JBrowse link
G Otub2 OTU deubiquitinase, ubiquitin aldehyde binding 2 increases expression ISO Lucanthone results in increased expression of OTUB2 mRNA CTD PMID:21148553 NCBI chr 6:122,545,029...122,563,651
Ensembl chr 6:122,545,061...122,563,644
JBrowse link
G Pbk PDZ binding kinase decreases expression ISO Lucanthone results in decreased expression of PBK mRNA CTD PMID:21148553 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
JBrowse link
G Pclaf PCNA clamp associated factor decreases expression ISO Lucanthone results in decreased expression of PCLAF mRNA CTD PMID:21148553 NCBI chr 8:66,420,673...66,432,568
Ensembl chr 8:66,420,587...66,432,994
Ensembl chr 8:66,420,587...66,432,994
JBrowse link
G Phgdh phosphoglycerate dehydrogenase decreases expression ISO Lucanthone results in decreased expression of PHGDH mRNA CTD PMID:21148553 NCBI chr 2:185,906,964...185,936,160
Ensembl chr 2:185,906,966...185,935,944
JBrowse link
G Plk1 polo-like kinase 1 decreases expression ISO Lucanthone results in decreased expression of PLK1 mRNA CTD PMID:21148553 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
JBrowse link
G Plk4 polo-like kinase 4 decreases expression ISO Lucanthone results in decreased expression of PLK4 mRNA CTD PMID:21148553 NCBI chr 2:123,802,512...123,820,942
Ensembl chr 2:123,802,512...123,820,942
JBrowse link
G Pole2 DNA polymerase epsilon 2, accessory subunit decreases expression ISO Lucanthone results in decreased expression of POLE2 mRNA CTD PMID:21148553 NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
JBrowse link
G Prc1 protein regulator of cytokinesis 1 decreases expression ISO Lucanthone results in decreased expression of PRC1 mRNA CTD PMID:21148553 NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765
JBrowse link
G Prim1 DNA primase subunit 1 decreases expression ISO Lucanthone results in decreased expression of PRIM1 mRNA CTD PMID:21148553 NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526
JBrowse link
G Prr11 proline rich 11 decreases expression ISO Lucanthone results in decreased expression of PRR11 mRNA CTD PMID:21148553 NCBI chr10:71,898,858...71,943,325
Ensembl chr10:71,901,202...71,921,012
JBrowse link
G Psat1 phosphoserine aminotransferase 1 decreases expression ISO Lucanthone results in decreased expression of PSAT1 mRNA CTD PMID:21148553 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psmc3ip PSMC3 interacting protein decreases expression ISO Lucanthone results in decreased expression of PSMC3IP mRNA CTD PMID:21148553 NCBI chr10:86,024,281...86,027,928
Ensembl chr10:86,023,950...86,027,423
JBrowse link
G Ptchd4 patched domain containing 4 increases expression ISO Lucanthone results in increased expression of PTCHD4 mRNA CTD PMID:21148553 NCBI chr 9:18,462,934...18,666,272
Ensembl chr 9:18,463,737...18,665,705
JBrowse link
G Pxdn peroxidasin increases expression ISO Lucanthone results in increased expression of PXDN mRNA CTD PMID:21148553 NCBI chr 6:46,580,749...46,658,345
Ensembl chr 6:46,580,761...46,658,345
JBrowse link
G Racgap1 Rac GTPase-activating protein 1 decreases expression ISO Lucanthone results in decreased expression of RACGAP1 mRNA CTD PMID:21148553 NCBI chr 7:130,750,936...130,780,891
Ensembl chr 7:130,750,936...130,780,831
JBrowse link
G Rad51 RAD51 recombinase decreases expression ISO Lucanthone results in decreased expression of RAD51 mRNA CTD PMID:21148553 NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression ISO Lucanthone results in decreased expression of RAD51AP1 mRNA CTD PMID:21148553 NCBI chr 4:159,759,454...159,772,524
Ensembl chr 4:159,759,459...159,772,524
JBrowse link
G RGD1306227 similar to 4833420G17Rik protein decreases expression ISO Lucanthone results in decreased expression of C5ORF34 mRNA CTD PMID:21148553 NCBI chr 2:51,553,223...51,577,090
Ensembl chr 2:51,555,432...51,577,085
JBrowse link
G RGD1562378 histone H4 variant H4-v.1 increases expression ISO Lucanthone results in increased expression of H4C14 mRNA CTD PMID:21148553
G Rrm2 ribonucleotide reductase regulatory subunit M2 decreases expression ISO Lucanthone results in decreased expression of RRM2 mRNA CTD PMID:21148553 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression ISO Lucanthone results in increased expression of SAT1 mRNA CTD PMID:21148553 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Scube1 signal peptide, CUB domain and EGF like domain containing 1 increases expression ISO Lucanthone results in increased expression of SCUBE1 mRNA CTD PMID:21148553 NCBI chr 7:114,759,016...114,880,995
Ensembl chr 7:114,759,010...114,880,940
JBrowse link
G Sectm1b secreted and transmembrane 1B increases expression ISO Lucanthone results in increased expression of SECTM1 mRNA CTD PMID:21148553 NCBI chr10:106,325,202...106,333,769
Ensembl chr10:106,325,203...106,333,769
JBrowse link
G Serpinb2 serpin family B member 2 increases expression ISO Lucanthone results in increased expression of SERPINB2 mRNA CTD PMID:21148553 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408
JBrowse link
G Sgo1 shugoshin 1 decreases expression ISO Lucanthone results in decreased expression of SGO1 mRNA CTD PMID:21148553 NCBI chr 9:6,672,109...6,687,908
Ensembl chr 9:6,672,123...6,687,805
JBrowse link
G Sgo2 shugoshin 2 decreases expression ISO Lucanthone results in decreased expression of SGO2 mRNA CTD PMID:21148553 NCBI chr 9:59,548,605...59,573,229
Ensembl chr 9:59,548,683...59,573,229
JBrowse link
G Shc4 SHC adaptor protein 4 increases expression ISO Lucanthone results in increased expression of SHC4 mRNA CTD PMID:21148553 NCBI chr 3:112,880,598...112,974,216
Ensembl chr 3:112,880,600...112,974,366
JBrowse link
G Shcbp1 SHC binding and spindle associated 1 decreases expression ISO Lucanthone results in decreased expression of SHCBP1 mRNA CTD PMID:21148553 NCBI chr16:84,672,276...84,703,839
Ensembl chr16:84,672,321...84,703,844
JBrowse link
G Slc1a4 solute carrier family 1 member 4 decreases expression ISO Lucanthone results in decreased expression of SLC1A4 mRNA CTD PMID:21148553 NCBI chr14:94,530,801...94,560,190
Ensembl chr14:94,529,084...94,560,418
JBrowse link
G Smc4 structural maintenance of chromosomes 4 decreases expression ISO Lucanthone results in decreased expression of SMC4 mRNA CTD PMID:21148553 NCBI chr 2:153,240,243...153,268,722
Ensembl chr 2:153,240,283...153,271,571
JBrowse link
G Spag5 sperm associated antigen 5 decreases expression ISO Lucanthone results in decreased expression of SPAG5 mRNA CTD PMID:21148553 NCBI chr10:63,198,717...63,216,746
Ensembl chr10:63,198,768...63,216,745
JBrowse link
G Spata18 spermatogenesis associated 18 increases expression ISO Lucanthone results in increased expression of SPATA18 mRNA CTD PMID:21148553 NCBI chr14:34,531,931...34,558,671
Ensembl chr14:34,531,061...34,558,687
JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex decreases expression ISO Lucanthone results in decreased expression of SPC25 mRNA CTD PMID:21148553 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959
JBrowse link
G Spdl1 spindle apparatus coiled-coil protein 1 decreases expression ISO Lucanthone results in decreased expression of SPDL1 mRNA CTD PMID:21148553 NCBI chr10:19,269,125...19,294,213
Ensembl chr10:19,269,127...19,294,127
JBrowse link
G Stmn1 stathmin 1 decreases expression ISO Lucanthone results in decreased expression of STMN1 mRNA CTD PMID:21148553 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sulf2 sulfatase 2 increases expression ISO Lucanthone results in increased expression of SULF2 mRNA CTD PMID:21148553 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415
JBrowse link
G Tcp11l2 t-complex 11 like 2 increases expression ISO Lucanthone results in increased expression of TCP11L2 mRNA CTD PMID:21148553 NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095
JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Lucanthone results in increased expression of TFPI2 mRNA CTD PMID:21148553 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression ISO Lucanthone results in increased expression of TIPARP mRNA CTD PMID:21148553 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
JBrowse link
G Tmem45a transmembrane protein 45A increases expression ISO Lucanthone results in increased expression of TMEM45A mRNA CTD PMID:21148553 NCBI chr11:43,713,309...43,799,526
Ensembl chr11:43,713,782...43,799,526
JBrowse link
G Tnfsf15 TNF superfamily member 15 increases expression ISO Lucanthone results in increased expression of TNFSF15 mRNA CTD PMID:21148553 NCBI chr 5:77,140,099...77,156,142
Ensembl chr 5:77,139,878...77,156,228
JBrowse link
G Top2a DNA topoisomerase II alpha decreases expression ISO Lucanthone results in decreased expression of TOP2A mRNA CTD PMID:21148553 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Tp53i3 tumor protein p53 inducible protein 3 increases expression ISO Lucanthone results in increased expression of TP53I3 mRNA CTD PMID:21148553 NCBI chr13:69,612,605...69,655,018
Ensembl chr13:69,620,792...69,652,475
JBrowse link
G Tp53inp1 tumor protein p53 inducible nuclear protein 1 increases expression ISO Lucanthone results in increased expression of TP53INP1 mRNA CTD PMID:21148553 NCBI chr 5:24,253,986...24,272,250
Ensembl chr 5:24,260,568...24,267,968
JBrowse link
G Tpx2 TPX2, microtubule nucleation factor decreases expression ISO Lucanthone results in decreased expression of TPX2 mRNA CTD PMID:21148553 NCBI chr 3:141,318,428...141,360,684
Ensembl chr 3:141,318,455...141,360,468
JBrowse link
G Ttk Ttk protein kinase decreases expression ISO Lucanthone results in decreased expression of TTK mRNA CTD PMID:21148553 NCBI chr 8:84,754,329...84,792,653
Ensembl chr 8:84,754,315...84,792,651
JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T decreases expression ISO Lucanthone results in decreased expression of UBE2T mRNA CTD PMID:21148553 NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835
JBrowse link
G Wdr76 WD repeat domain 76 decreases expression ISO Lucanthone results in decreased expression of WDR76 mRNA CTD PMID:21148553 NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840
JBrowse link
G Xrcc2 X-ray repair cross complementing 2 decreases expression ISO Lucanthone results in decreased expression of XRCC2 mRNA CTD PMID:21148553 NCBI chr 4:9,423,873...9,502,980
Ensembl chr 4:9,423,898...9,442,482
JBrowse link
G Zwint ZW10 interacting kinetochore protein decreases expression ISO Lucanthone results in decreased expression of ZWINT mRNA CTD PMID:21148553 NCBI chr20:15,938,157...15,953,997
Ensembl chr20:15,938,157...15,953,957
JBrowse link
oltipraz term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases expression ISO oltipraz results in decreased expression of ABCB11 mRNA CTD PMID:16837569 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO oltipraz results in increased expression of ABCB1 mRNA CTD PMID:16837569 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC1 protein CTD PMID:18032408 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 multiple interactions
increases expression
ISO
EXP
[Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC2 protein; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA
oltipraz results in increased expression of ABCC2 mRNA; oltipraz results in increased expression of ABCC2 protein
CTD PMID:12920174 PMID:15833929 PMID:16837569 PMID:18032408 PMID:25752797 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
multiple interactions
ISO
EXP
oltipraz results in increased expression of ABCC3 mRNA
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC3 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of ABCC3 mRNA]
[oltipraz results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite
oltipraz results in increased expression of ABCC3 mRNA; oltipraz results in increased expression of ABCC3 protein
CTD PMID:12920174 PMID:15833929 PMID:16837569 PMID:22496397 PMID:30114225 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions
increases expression
ISO [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC4 protein; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC4 mRNA]
oltipraz results in increased expression of ABCC4 mRNA; oltipraz results in increased expression of ABCC4 protein
oltipraz promotes the reaction [ABCC4 protein results in increased transport of Arsenic]
CTD PMID:15833929 PMID:18032408 PMID:20395535 PMID:22496397 PMID:25752797 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc5 ATP binding cassette subfamily C member 5 multiple interactions
increases expression
ISO [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC5 protein; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC5 mRNA
oltipraz results in increased expression of ABCC5 mRNA
CTD PMID:15833929 PMID:18032408 NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 multiple interactions
increases expression
ISO [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC6 mRNA
oltipraz results in increased expression of ABCC6 mRNA
CTD PMID:15833929 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases activity
increases expression
ISO oltipraz promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]
oltipraz results in increased activity of ABCG2 protein
oltipraz results in increased expression of ABCG2 mRNA
CTD PMID:15917307 PMID:16837569 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 multiple interactions ISO [oltipraz co-treated with NFE2L2 protein mutant form] affects the expression of ABCG5 mRNA CTD PMID:22496397 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
increases activity
ISO [oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]] which results in increased expression of CYP1A1 mRNA; oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]; resveratrol inhibits the reaction [[oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]] which results in increased expression of CYP1A1 mRNA]
oltipraz results in increased activity of AHR protein
CTD PMID:11959854 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases activity EXP oltipraz results in increased activity of AKR7A3 protein CTD PMID:9328168 NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
JBrowse link
G Alb albumin decreases expression EXP oltipraz results in decreased expression of ALB mRNA CTD PMID:9395210 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions
increases expression
ISO [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ALDH1A1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ALDH1A1 mRNA] CTD PMID:17998271 PMID:22496397 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Lithocholic Acid co-treated with oltipraz] results in increased expression of BAX mRNA CTD PMID:19433268 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Lithocholic Acid co-treated with oltipraz] results in increased expression of BCL2L1 mRNA CTD PMID:19433268 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions EXP [Dexamethasone co-treated with oltipraz] results in increased activity of CEBPB protein; N-acetylsphingosine inhibits the reaction [oltipraz results in increased localization of CEBPB protein]; oltipraz promotes the reaction [CEBPB protein binds to GSTA2 promoter]; oltipraz results in increased localization of and results in increased activity of CEBPB protein CTD PMID:12509401 PMID:15319326 PMID:15870285 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Ces1d carboxylesterase 1D increases expression
multiple interactions
ISO oltipraz results in increased expression of CES1 mRNA
NFE2L2 protein promotes the reaction [oltipraz results in increased expression of CES1 mRNA]
CTD PMID:30114225 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Ces2c carboxylesterase 2C increases expression
multiple interactions
ISO oltipraz results in increased expression of CES2C mRNA
NFE2L2 protein affects the reaction [oltipraz results in increased expression of CES2C mRNA]
CTD PMID:22429928 NCBI chr 1:260,391,190...260,398,757
Ensembl chr 1:260,388,902...260,398,790
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
affects metabolic processing
decreases activity
affects activity
ISO
EXP
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [oltipraz results in increased expression of CYP1A1 mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [[oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA]; [oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]] which results in increased expression of CYP1A1 mRNA; [oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA; oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]; oltipraz results in increased expression of and results in increased activity of CYP1A1 protein; resveratrol inhibits the reaction [[oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]] which results in increased expression of CYP1A1 mRNA]; resveratrol inhibits the reaction [oltipraz results in increased expression of CYP1A1 mRNA]
CYP1A1 protein affects the metabolism of oltipraz
oltipraz results in increased expression of CYP1A1 mRNA; oltipraz results in increased expression of CYP1A1 protein
oltipraz metabolite results in decreased activity of CYP1A1 protein
oltipraz affects the activity of CYP1A1 protein
CTD PMID:10775323 PMID:11959854 PMID:15831204 PMID:15890477 PMID:15920769 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases expression
multiple interactions
increases activity
affects metabolic processing
ISO
EXP
oltipraz metabolite results in decreased activity of CYP1A2 protein; oltipraz results in decreased activity of CYP1A2 protein
oltipraz results in increased expression of CYP1A2 mRNA
NFE2L2 protein affects the reaction [oltipraz results in increased expression of CYP1A2 mRNA]
oltipraz results in increased activity of CYP1A2 protein
oltipraz inhibits the reaction [CYP1A2 results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline]
CYP1A2 protein affects the metabolism of oltipraz
CTD PMID:8625305 PMID:10775323 PMID:15831204 PMID:15920769 PMID:22496397 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
affects activity
increases expression
ISO oltipraz metabolite results in decreased activity of CYP1B1 protein
oltipraz affects the activity of CYP1B1 protein
oltipraz results in increased expression of CYP1B1 mRNA
CTD PMID:10775323 PMID:15890477 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 affects metabolic processing
increases expression
EXP
ISO
CYP2B1 protein affects the metabolism of oltipraz
oltipraz results in increased expression of CYP2B10 mRNA
CTD PMID:15831204 PMID:15920769 PMID:17627975 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 affects metabolic processing EXP CYP2B2 protein affects the metabolism of oltipraz CTD PMID:15831204 PMID:15920769 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases activity
increases expression
ISO oltipraz results in decreased activity of CYP2B6 protein
oltipraz results in increased expression of CYP2B6 mRNA; oltipraz results in increased expression of CYP2B6 protein
CTD PMID:19833192 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 affects metabolic processing EXP CYP2C11 protein affects the metabolism of oltipraz CTD PMID:15831204 PMID:15920769 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2d1 cytochrome P450, family 2, subfamily d, polypeptide 1 affects metabolic processing EXP CYP2D1 protein affects the metabolism of oltipraz CTD PMID:15831204 PMID:15920769 NCBI chr 7:113,908,950...113,913,420 JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects activity ISO oltipraz affects the activity of CYP2E1 protein CTD PMID:10775323 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects metabolic processing
decreases activity
affects activity
EXP
ISO
CYP3A2 protein affects the metabolism of oltipraz
oltipraz metabolite results in decreased activity of CYP3A4 protein; oltipraz results in decreased activity of CYP3A4 protein
oltipraz affects the activity of CYP3A4 protein
CTD PMID:10775323 PMID:15831204 PMID:15920769 PMID:19833192 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 affects metabolic processing EXP CYP3A23-3A1 protein affects the metabolism of oltipraz CTD PMID:15831204 PMID:15920769 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 increases expression EXP oltipraz results in increased expression of GSTA3 mRNA; oltipraz results in increased expression of GSTA3 protein CTD PMID:9203627 PMID:9794803 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 increases expression
multiple interactions
EXP
ISO
oltipraz results in increased expression of GSTA2 mRNA; oltipraz results in increased expression of GSTA2 protein
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTA1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTA1 mRNA]
oltipraz results in increased expression of GSTA1 mRNA; oltipraz results in increased expression of GSTA1 protein
2-tert-butylhydroquinone inhibits the reaction [oltipraz results in increased expression of GSTA2 mRNA]; Dexamethasone inhibits the reaction [oltipraz results in increased expression of GSTA2 mRNA]; Dexamethasone inhibits the reaction [oltipraz results in increased expression of GSTA2 protein]; N-acetylsphingosine inhibits the reaction [oltipraz results in increased expression of GSTA2 protein]; oltipraz promotes the reaction [CEBPB protein binds to GSTA2 promoter]
CTD PMID:9203627 PMID:11309284 PMID:12242683 PMID:12509401 PMID:15155840 More... NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression ISO oltipraz results in increased expression of GSTA2 protein CTD PMID:11309284 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
JBrowse link
G Gsta5 glutathione S-transferase alpha 5 increases activity
increases expression
EXP oltipraz results in increased activity of GSTA5 protein
oltipraz results in increased expression of GSTA5 mRNA; oltipraz results in increased expression of GSTA5 protein
CTD PMID:8051171 PMID:8625305 PMID:9203627 PMID:9328168 NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
JBrowse link
G Gsta6 glutathione S-transferase alpha 6 increases expression
multiple interactions
ISO oltipraz results in increased expression of GSTA1 mRNA; oltipraz results in increased expression of GSTA1 protein
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTA1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTA1 mRNA]
CTD PMID:11309284 PMID:22496397 NCBI chr 9:23,743,262...23,806,260
Ensembl chr 9:23,744,288...23,801,131
JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions
increases expression
ISO
EXP
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM1 mRNA] CTD PMID:9203627 PMID:18723825 PMID:22496397 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions
increases expression
ISO [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM2 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM2 mRNA] CTD PMID:18723825 PMID:22496397 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm4 glutathione S-transferase mu 4 multiple interactions
increases expression
ISO [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM4 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM4 mRNA] CTD PMID:18723825 PMID:22496397 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
increases expression
ISO
EXP
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM3 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM3 mRNA]
oltipraz results in increased expression of GSTM3 protein
CTD PMID:9794803 PMID:18723825 PMID:22496397 NCBI chr 2:195,531,627...195,534,562
Ensembl chr 2:195,531,495...195,534,553
JBrowse link
G Gstp1 glutathione S-transferase pi 1 increases expression
multiple interactions
ISO
EXP
oltipraz results in increased expression of GSTP1 mRNA
oltipraz results in increased expression of GSTP1 protein
oltipraz results in increased expression of and results in increased activity of GSTP1 protein
CTD PMID:9794803 PMID:15374950 PMID:16950796 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
JBrowse link
G Gstt1 glutathione S-transferase theta 1 affects localization
increases expression
EXP oltipraz affects the localization of GSTT1 protein
oltipraz results in increased expression of GSTT1 protein
CTD PMID:9794803 PMID:9855024 PMID:10413528 NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
JBrowse link
G Ivl involucrin decreases expression ISO oltipraz results in decreased expression of IVL protein CTD PMID:10769631 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member multiple interactions ISO [Lithocholic Acid co-treated with oltipraz] results in increased expression of MCL1 mRNA CTD PMID:19433268 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression
multiple interactions
ISO oltipraz results in increased expression of MGMT mRNA
oltipraz results in increased expression of and results in increased activity of MGMT protein
CTD PMID:16950796 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 multiple interactions
increases expression
ISO [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of MGST3 mRNA
oltipraz results in increased expression of MGST3 mRNA
CTD PMID:18723825 PMID:22496397 NCBI chr13:79,526,541...79,547,479
Ensembl chr13:79,526,541...79,547,411
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects activity
increases activity
multiple interactions
affects response to substance
ISO oltipraz affects the activity of NFE2L2 protein
oltipraz results in increased activity of NFE2L2 protein
[oltipraz co-treated with NFE2L2 protein mutant form] affects the expression of ABCG5 mRNA; [oltipraz co-treated with NFE2L2 protein mutant form] results in decreased expression of UGT2B1 mRNA; [oltipraz co-treated with NFE2L2 protein mutant form] results in decreased expression of UGT2B35 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC5 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC6 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ALDH1A1 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTA1 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTA4 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM1 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM2 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM3 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM4 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of MGST3 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC3 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC4 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ALDH1A1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of CES1G mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of CES2C mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of CYP1A2 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTA1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTA4 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM2 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM3 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM4 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of SULT3A1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT1A6A mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT2B34 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT2B36 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of ABCC3 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of CES1 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of NQO1 mRNA]; oltipraz binds to and results in increased activity of NFE2L2 protein
NFE2L2 protein affects the susceptibility to oltipraz
CTD PMID:11309284 PMID:15833929 PMID:15919853 PMID:19150646 PMID:20086057 More... NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
multiple interactions
increases expression
ISO oltipraz results in increased activity of NQO1 protein
oltipraz promotes the reaction [Cisplatin results in increased expression of NQO1 mRNA]
oltipraz metabolite results in increased expression of NQO1 protein; oltipraz results in increased expression of NQO1 mRNA; oltipraz results in increased expression of NQO1 protein
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of NQO1 mRNA]; oltipraz promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NQO1 mRNA]
CTD PMID:11309284 PMID:12407167 PMID:15919853 PMID:17627975 PMID:18488193 More... NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO oltipraz inhibits the reaction [Lithocholic Acid affects the localization of and results in increased activity of NR1I3 protein] CTD PMID:19433268 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression ISO oltipraz results in decreased expression of SLC10A1 mRNA CTD PMID:16837569 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670
JBrowse link
G Slc22a7 solute carrier family 22 member 7 decreases expression ISO oltipraz results in decreased expression of SLC22A7 mRNA CTD PMID:16837569 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
JBrowse link
G Slco1b2 solute carrier organic anion transporter family member 1B2 decreases expression ISO oltipraz results in decreased expression of SLCO1B3 mRNA CTD PMID:16837569 NCBI chr 4:174,551,463...174,619,988
Ensembl chr 4:174,551,480...174,619,981
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression ISO oltipraz results in increased expression of SLCO2B1 mRNA CTD PMID:15919853 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Sod2 superoxide dismutase 2 increases expression EXP oltipraz results in increased expression of SOD2 mRNA CTD PMID:9395210 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO oltipraz results in increased expression of TXNRD1 mRNA CTD PMID:16451816 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO oltipraz inhibits the reaction [Doxorubicin results in decreased expression of UCP2 protein] CTD PMID:29061315 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression
multiple interactions
ISO oltipraz results in increased expression of UGT1A1 mRNA
oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A7 mRNA]
CTD PMID:15374950 PMID:19144771 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases expression ISO oltipraz results in increased expression of UGT1A5 mRNA CTD PMID:19144771 NCBI chr 9:88,762,250...88,808,465 JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 multiple interactions
increases expression
ISO oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A6 mRNA]
oltipraz results in increased expression of UGT1A6 mRNA
CTD PMID:15374950 PMID:19144771 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ugt2a3 UDP glucuronosyltransferase family 2 member A3 decreases expression ISO oltipraz results in decreased expression of UGT2A3 mRNA CTD PMID:22496397 NCBI chr14:20,572,825...20,590,295
Ensembl chr14:20,572,808...20,590,729
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 decreases expression
multiple interactions
ISO oltipraz results in decreased expression of UGT2B1 mRNA
[oltipraz co-treated with NFE2L2 protein mutant form] results in decreased expression of UGT2B1 mRNA
CTD PMID:19144771 PMID:22496397 NCBI chr14:21,024,035...21,035,784
Ensembl chr14:21,024,006...21,035,986
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases expression
multiple interactions
ISO oltipraz results in increased expression of UGT2B34 mRNA
NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT2B34 mRNA]
CTD PMID:22496397 NCBI chr14:20,896,682...20,919,604
Ensembl chr14:20,896,682...20,919,604
JBrowse link
phytol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aldh3a2 aldehyde dehydrogenase 3 family, member A2 increases expression
multiple interactions
ISO Phytol results in increased expression of ALDH3A2 protein
PPARA protein affects the reaction [Phytol results in increased expression of ALDH3A2 protein]
CTD PMID:17015885 NCBI chr10:45,928,313...45,949,366
Ensembl chr10:45,908,524...45,949,281
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Phytol inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein] CTD PMID:30520250 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Phytol inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein] CTD PMID:30520250 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 multiple interactions ISO Phytol inhibits the reaction [Benzo(a)pyrene results in increased expression of CASP3 protein] CTD PMID:30520250 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Phytol co-treated with Benzo(a)pyrene] results in decreased expression of CASP9 protein CTD PMID:30520250 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression
multiple interactions
ISO Phytol results in increased expression of CAT
Phytol inhibits the reaction [Benzo(a)pyrene results in increased expression of CAT protein]
CTD PMID:19188468 PMID:30520250 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO Phytol inhibits the reaction [Benzo(a)pyrene results in increased expression of GSR protein] CTD PMID:30520250 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine affects the reaction [Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK1 protein]]; Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK1 protein] CTD PMID:29486182 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine affects the reaction [Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK3 protein]]; Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK3 protein] CTD PMID:29486182 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mitf melanocyte inducing transcription factor multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]]; [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein; Acetylcysteine inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]] which results in decreased ubiquitination of MITF protein]; benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]]; Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein] CTD PMID:29486182 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects metabolic processing
multiple interactions
ISO PPARA protein affects the metabolism of Phytol
PPARA protein affects the reaction [Phytol results in increased expression of ALDH3A2 protein]
CTD PMID:17015885 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1b PPARG coactivator 1 beta increases activity ISO Phytol results in increased activity of PPARGC1B protein CTD PMID:17015885 NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194
JBrowse link
G Tyr tyrosinase multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of TYR protein]]; Phytol inhibits the reaction [alpha-MSH results in increased expression of TYR protein] CTD PMID:29486182 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
JBrowse link
G Tyrp1 tyrosinase-related protein 1 multiple interactions ISO Phytol inhibits the reaction [alpha-MSH results in increased expression of TYRP1 protein] CTD PMID:29486182 NCBI chr 5:95,280,982...95,299,516
Ensembl chr 5:95,280,982...95,299,516
JBrowse link

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  CHEBI ontology 19821
    role 19769
      application 19481
        pharmaceutical 19329
          drug 19329
            antiinfective agent 14113
              antiparasitic agent 9267
                anthelminthic drug 4952
                  antiplatyhelmintic drug 450
                    bithionol 4
                    schistosomicide drug + 446
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