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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cevane
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Accession:CHEBI:35651 term browser browse the term
Definition:A steroid alkaloid fundamental parent that has formula C27H45N.
Synonyms:related_synonym: (22S,25S)-5beta-cevanine;   Formula=C27H45N;   InChI=1S/C27H45N/c1-17-7-12-26-18(2)20-10-11-21-22-9-8-19-6-4-5-13-27(19,3)25(22)14-23(21)24(20)16-28(26)15-17/h17-26H,4-16H2,1-3H3/t17-,18+,19-,20+,21-,22-,23+,24+,25-,26-,27-/m0/s1;   InChIKey=GRTNBDIOACKBEA-AABZRHAESA-N;   SMILES=[H][C@@]12CC[C@H](C)CN1C[C@]1([H])[C@]([H])(CC[C@@]3([H])[C@]4([H])CC[C@]5([H])CCCC[C@]5(C)[C@@]4([H])C[C@@]13[H])[C@H]2C



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veratridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain derived neurotrophic factor multiple interactions
increases expression
EXP
ISO
cypermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]; Permethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]
Tetrodotoxin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]
CTD PMID:11082455 PMID:16166269 NCBI chr 2:109,505,045...109,557,388
Ensembl chr 2:109,505,045...109,557,352
JBrowse link
G Calca calcitonin/calcitonin-related polypeptide, alpha multiple interactions
increases secretion
ISO nociceptin (1-13) amide inhibits the reaction [Veratridine results in increased secretion of CALCA protein] CTD PMID:17640294 NCBI chr 7:114,225,223...114,236,145
Ensembl chr 7:114,230,713...114,235,592
JBrowse link
G Fos FBJ osteosarcoma oncogene multiple interactions
increases expression
EXP
ISO
cypermethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA]; Permethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA] CTD PMID:11082455 PMID:19463813 NCBI chr12:85,520,664...85,524,048
Ensembl chr12:85,520,664...85,524,047
JBrowse link
G Grm5 glutamate receptor, metabotropic 5 multiple interactions ISO [6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Veratridine results in increased secretion of Dopamine] CTD PMID:12907309 NCBI chr 7:87,233,212...87,784,271
Ensembl chr 7:87,233,376...87,784,115
JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
ISO Tetrodotoxin inhibits the reaction [Veratridine results in increased expression of NPY mRNA] CTD PMID:2233698 NCBI chr 6:49,799,690...49,806,487
Ensembl chr 6:49,799,690...49,806,487
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22188
    chemical entity 22187
      atom 22180
        nonmetal atom 22063
          carbon atom 21840
            organic molecular entity 21840
              lipid 18829
                steroid 14880
                  cevane 5
                    cevine 0
                    veracevine 0
                    veratridine 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 22188
    subatomic particle 22180
      composite particle 22180
        hadron 22180
          baryon 22180
            nucleon 22180
              atomic nucleus 22180
                atom 22180
                  main group element atom 22114
                    main group molecular entity 22114
                      s-block molecular entity 21706
                        hydrogen molecular entity 21622
                          hydrides 20748
                            organic hydride 20297
                              organic fundamental parent 20297
                                natural product fundamental parent 15204
                                  alkaloid fundamental parent 2878
                                    steroid alkaloid fundamental parent 13
                                      cevane 5
                                        cevine 0
                                        veracevine 0
                                        veratridine 5
paths to the root