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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cevane
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Accession:CHEBI:35651 term browser browse the term
Definition:A steroid alkaloid fundamental parent that has formula C27H45N.
Synonyms:related_synonym: (22S,25S)-5beta-cevanine;   Formula=C27H45N;   InChI=1S/C27H45N/c1-17-7-12-26-18(2)20-10-11-21-22-9-8-19-6-4-5-13-27(19,3)25(22)14-23(21)24(20)16-28(26)15-17/h17-26H,4-16H2,1-3H3/t17-,18+,19-,20+,21-,22-,23+,24+,25-,26-,27-/m0/s1;   InChIKey=GRTNBDIOACKBEA-AABZRHAESA-N;   SMILES=[H][C@@]12CC[C@H](C)CN1C[C@]1([H])[C@]([H])(CC[C@@]3([H])[C@]4([H])CC[C@]5([H])CCCC[C@]5(C)[C@@]4([H])C[C@@]13[H])[C@H]2C



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veratridine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
ISO
EXP
cypermethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]; Permethrin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]
Tetrodotoxin inhibits the reaction [Veratridine results in increased expression of BDNF mRNA]
CTD PMID:11082455 PMID:16166269 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions
increases secretion
EXP nociceptin (1-13) amide inhibits the reaction [Veratridine results in increased secretion of CALCA protein] CTD PMID:17640294 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
ISO
EXP
cypermethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA]; Permethrin inhibits the reaction [Veratridine results in increased expression of FOS mRNA] CTD PMID:11082455 PMID:19463813 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Grm5 glutamate metabotropic receptor 5 multiple interactions EXP [6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Veratridine results in increased secretion of Dopamine] CTD PMID:12907309 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
EXP Tetrodotoxin inhibits the reaction [Veratridine results in increased expression of NPY mRNA] CTD PMID:2233698 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19765
    chemical entity 19763
      atom 19763
        nonmetal atom 19702
          carbon atom 19654
            organic molecular entity 19654
              lipid 17801
                steroid 14388
                  cevane 5
                    cevine 0
                    veracevine 0
                    veratridine 5
Path 2
Term Annotations click to browse term
  CHEBI ontology 19765
    subatomic particle 19763
      composite particle 19763
        hadron 19763
          baryon 19763
            nucleon 19763
              atomic nucleus 19763
                atom 19763
                  main group element atom 19712
                    main group molecular entity 19712
                      s-block molecular entity 19567
                        hydrogen molecular entity 19558
                          hydrides 19031
                            organic hydride 18634
                              organic fundamental parent 18634
                                natural product fundamental parent 14704
                                  alkaloid fundamental parent 2857
                                    steroid alkaloid fundamental parent 13
                                      cevane 5
                                        cevine 0
                                        veracevine 0
                                        veratridine 5
paths to the root