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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:adrenergic uptake inhibitor
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Accession:CHEBI:35640 term browser browse the term
Definition:Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Synonyms:related_synonym: ARI;   NERI;   NRI;   adrenergic reuptake inhibitor;   adrenergic reuptake inhibitors;   adrenergic uptake inhibitors;   norepinephrine reuptake inhibitor;   norepinephrine reuptake inhibitors



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Your selection has 4716 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

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  • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19823
        role 19773
          biological role 19773
            pharmacological role 18852
              neurotransmitter agent 16458
                adrenergic agent 8985
                  adrenergic uptake inhibitor 4716
                    (R,R)-tramadol + 32
                    (R,R)-tramadol hydrochloride + 0
                    (S)-amphetamine + 3495
                    (S,S)-tramadol + 32
                    (S,S)-tramadol hydrochloride + 0
                    amezinium + 0
                    amezinium metilsulfate 0
                    amitriptyline + 190
                    amoxapine 8
                    amphetamine + 2214
                    atomoxetine + 1
                    atomoxetine hydrochloride 1
                    benzphetamine + 2
                    benzphetamine hydrochloride 0
                    cocaine 1440
                    desipramine + 46
                    imipramine + 132
                    methylphenidate 128
                    mianserin + 17
                    nefopam 1
                    nefopam hydrochloride 0
                    nisoxetine 2
                    nortriptyline 21
                    reserpine 119
                    tetrabenazine 2
                    tramadol 32
                    tramadol hydrochloride 0
                    venlafaxine + 176
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19823
        role 19773
          application 19486
            pharmaceutical 19335
              drug 19335
                neurotransmitter agent 16458
                  adrenergic agent 8985
                    adrenergic uptake inhibitor 4716
                      (R,R)-tramadol + 32
                      (R,R)-tramadol hydrochloride + 0
                      (S)-amphetamine + 3495
                      (S,S)-tramadol + 32
                      (S,S)-tramadol hydrochloride + 0
                      amezinium + 0
                      amezinium metilsulfate 0
                      amitriptyline + 190
                      amoxapine 8
                      amphetamine + 2214
                      atomoxetine + 1
                      atomoxetine hydrochloride 1
                      benzphetamine + 2
                      benzphetamine hydrochloride 0
                      cocaine 1440
                      desipramine + 46
                      imipramine + 132
                      methylphenidate 128
                      mianserin + 17
                      nefopam 1
                      nefopam hydrochloride 0
                      nisoxetine 2
                      nortriptyline 21
                      reserpine 119
                      tetrabenazine 2
                      tramadol 32
                      tramadol hydrochloride 0
                      venlafaxine + 176
    paths to the root