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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:adrenergic uptake inhibitor
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Accession:CHEBI:35640 term browser browse the term
Definition:Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Synonyms:related_synonym: ARI;   NERI;   NRI;   adrenergic reuptake inhibitor;   adrenergic reuptake inhibitors;   adrenergic uptake inhibitors;   norepinephrine reuptake inhibitor;   norepinephrine reuptake inhibitors


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Your selection has 4810 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

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    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19911
        role 19854
          biological role 19852
            pharmacological role 19106
              neurotransmitter agent 16806
                adrenergic agent 9181
                  adrenergic uptake inhibitor 4810
                    (R,R)-tramadol + 38
                    (R,R)-tramadol hydrochloride + 0
                    (S)-amphetamine + 3609
                    (S,S)-tramadol + 38
                    (S,S)-tramadol hydrochloride + 0
                    amezinium + 0
                    amezinium metilsulfate 0
                    amitriptyline + 189
                    amoxapine 8
                    amphetamine + 2222
                    atomoxetine + 1
                    atomoxetine hydrochloride 1
                    benzphetamine + 2
                    benzphetamine hydrochloride 0
                    cocaine 1445
                    desipramine + 51
                    imipramine + 136
                    methylphenidate 141
                    mianserin + 17
                    nefopam 1
                    nefopam hydrochloride 0
                    nisoxetine 2
                    nortriptyline 21
                    reserpine 120
                    tetrabenazine 2
                    tramadol 38
                    tramadol hydrochloride 0
                    venlafaxine + 182
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19911
        role 19854
          application 19722
            pharmaceutical 19556
              drug 19556
                neurotransmitter agent 16806
                  adrenergic agent 9181
                    adrenergic uptake inhibitor 4810
                      (R,R)-tramadol + 38
                      (R,R)-tramadol hydrochloride + 0
                      (S)-amphetamine + 3609
                      (S,S)-tramadol + 38
                      (S,S)-tramadol hydrochloride + 0
                      amezinium + 0
                      amezinium metilsulfate 0
                      amitriptyline + 189
                      amoxapine 8
                      amphetamine + 2222
                      atomoxetine + 1
                      atomoxetine hydrochloride 1
                      benzphetamine + 2
                      benzphetamine hydrochloride 0
                      cocaine 1445
                      desipramine + 51
                      imipramine + 136
                      methylphenidate 141
                      mianserin + 17
                      nefopam 1
                      nefopam hydrochloride 0
                      nisoxetine 2
                      nortriptyline 21
                      reserpine 120
                      tetrabenazine 2
                      tramadol 38
                      tramadol hydrochloride 0
                      venlafaxine + 182
    paths to the root