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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:adrenergic uptake inhibitor
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Accession:CHEBI:35640 term browser browse the term
Definition:Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Synonyms:related_synonym: ARI;   NERI;   NRI;   adrenergic reuptake inhibitor;   adrenergic reuptake inhibitors;   adrenergic uptake inhibitors;   norepinephrine reuptake inhibitor;   norepinephrine reuptake inhibitors



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Your selection has 4764 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

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  • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19818
        role 19790
          biological role 19788
            pharmacological role 19035
              neurotransmitter agent 16672
                adrenergic agent 9156
                  adrenergic uptake inhibitor 4764
                    (R,R)-tramadol + 34
                    (R,R)-tramadol hydrochloride + 0
                    (S)-amphetamine + 3540
                    (S,S)-tramadol + 34
                    (S,S)-tramadol hydrochloride + 0
                    amezinium + 0
                    amezinium metilsulfate 0
                    amitriptyline + 190
                    amoxapine 8
                    amphetamine + 2220
                    atomoxetine + 1
                    atomoxetine hydrochloride 1
                    benzphetamine + 2
                    benzphetamine hydrochloride 0
                    cocaine 1446
                    desipramine + 48
                    imipramine + 134
                    methylphenidate 129
                    mianserin + 17
                    nefopam 1
                    nefopam hydrochloride 0
                    nisoxetine 2
                    nortriptyline 21
                    reserpine 120
                    tetrabenazine 2
                    tramadol 34
                    tramadol hydrochloride 0
                    venlafaxine + 181
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19818
        role 19790
          application 19622
            pharmaceutical 19499
              drug 19499
                neurotransmitter agent 16672
                  adrenergic agent 9156
                    adrenergic uptake inhibitor 4764
                      (R,R)-tramadol + 34
                      (R,R)-tramadol hydrochloride + 0
                      (S)-amphetamine + 3540
                      (S,S)-tramadol + 34
                      (S,S)-tramadol hydrochloride + 0
                      amezinium + 0
                      amezinium metilsulfate 0
                      amitriptyline + 190
                      amoxapine 8
                      amphetamine + 2220
                      atomoxetine + 1
                      atomoxetine hydrochloride 1
                      benzphetamine + 2
                      benzphetamine hydrochloride 0
                      cocaine 1446
                      desipramine + 48
                      imipramine + 134
                      methylphenidate 129
                      mianserin + 17
                      nefopam 1
                      nefopam hydrochloride 0
                      nisoxetine 2
                      nortriptyline 21
                      reserpine 120
                      tetrabenazine 2
                      tramadol 34
                      tramadol hydrochloride 0
                      venlafaxine + 181
    paths to the root