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ONTOLOGY REPORT - ANNOTATIONS


Term:adrenergic uptake inhibitor
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Accession:CHEBI:35640 term browser browse the term
Definition:Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Synonyms:related_synonym: ARI;   NERI;   NRI;   adrenergic reuptake inhibitor;   adrenergic reuptake inhibitors;   adrenergic uptake inhibitors;   norepinephrine reuptake inhibitor;   norepinephrine reuptake inhibitors


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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      biological role 19604
        pharmacological role 18687
          neurotransmitter agent 16229
            adrenergic agent 7911
              adrenergic uptake inhibitor 3004
                (R,R)-tramadol + 25
                (R,R)-tramadol hydrochloride + 0
                (S)-amphetamine + 1559
                (S,S)-tramadol + 25
                (S,S)-tramadol hydrochloride + 0
                amitriptyline + 186
                amoxapine 7
                amphetamine + 25
                atomoxetine + 1
                atomoxetine hydrochloride 1
                benzphetamine + 1
                benzphetamine hydrochloride 0
                cocaine 1428
                desipramine + 44
                imipramine + 123
                methylphenidate 128
                mianserin + 17
                nefopam 1
                nefopam hydrochloride 0
                nisoxetine 2
                nortriptyline 20
                reserpine 116
                tetrabenazine 2
                tramadol 25
                tramadol hydrochloride 0
                venlafaxine + 176
Path 2
Term Annotations click to browse term
  CHEBI ontology 19662
    role 19606
      application 19232
        pharmaceutical 19094
          drug 19094
            neurotransmitter agent 16229
              adrenergic agent 7911
                adrenergic uptake inhibitor 3004
                  (R,R)-tramadol + 25
                  (R,R)-tramadol hydrochloride + 0
                  (S)-amphetamine + 1559
                  (S,S)-tramadol + 25
                  (S,S)-tramadol hydrochloride + 0
                  amitriptyline + 186
                  amoxapine 7
                  amphetamine + 25
                  atomoxetine + 1
                  atomoxetine hydrochloride 1
                  benzphetamine + 1
                  benzphetamine hydrochloride 0
                  cocaine 1428
                  desipramine + 44
                  imipramine + 123
                  methylphenidate 128
                  mianserin + 17
                  nefopam 1
                  nefopam hydrochloride 0
                  nisoxetine 2
                  nortriptyline 20
                  reserpine 116
                  tetrabenazine 2
                  tramadol 25
                  tramadol hydrochloride 0
                  venlafaxine + 176
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