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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:adrenergic uptake inhibitor
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Accession:CHEBI:35640 term browser browse the term
Definition:Adrenergic uptake inhibitors are drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin.
Synonyms:related_synonym: ARI;   NERI;   NRI;   adrenergic reuptake inhibitor;   adrenergic reuptake inhibitors;   adrenergic uptake inhibitors;   norepinephrine reuptake inhibitor;   norepinephrine reuptake inhibitors


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Your selection has 4808 annotated objects. The maximum number of objects that can be shown is 2000. The list is too large to display.

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    • Term paths to the root
    Path 1
    Term Annotations click to browse term
      CHEBI ontology 19876
        role 19851
          biological role 19849
            pharmacological role 19067
              neurotransmitter agent 16726
                adrenergic agent 9181
                  adrenergic uptake inhibitor 4808
                    (R,R)-tramadol + 36
                    (R,R)-tramadol hydrochloride + 0
                    (S)-amphetamine + 3604
                    (S,S)-tramadol + 36
                    (S,S)-tramadol hydrochloride + 0
                    amezinium + 0
                    amezinium metilsulfate 0
                    amitriptyline + 189
                    amoxapine 8
                    amphetamine + 2213
                    atomoxetine + 1
                    atomoxetine hydrochloride 1
                    benzphetamine + 2
                    benzphetamine hydrochloride 0
                    cocaine 1442
                    desipramine + 51
                    imipramine + 133
                    methylphenidate 140
                    mianserin + 17
                    nefopam 1
                    nefopam hydrochloride 0
                    nisoxetine 2
                    nortriptyline 21
                    reserpine 120
                    tetrabenazine 2
                    tramadol 38
                    tramadol hydrochloride 0
                    venlafaxine + 181
    Path 2
    Term Annotations click to browse term
      CHEBI ontology 19876
        role 19851
          application 19687
            pharmaceutical 19514
              drug 19514
                neurotransmitter agent 16726
                  adrenergic agent 9181
                    adrenergic uptake inhibitor 4808
                      (R,R)-tramadol + 36
                      (R,R)-tramadol hydrochloride + 0
                      (S)-amphetamine + 3604
                      (S,S)-tramadol + 36
                      (S,S)-tramadol hydrochloride + 0
                      amezinium + 0
                      amezinium metilsulfate 0
                      amitriptyline + 189
                      amoxapine 8
                      amphetamine + 2213
                      atomoxetine + 1
                      atomoxetine hydrochloride 1
                      benzphetamine + 2
                      benzphetamine hydrochloride 0
                      cocaine 1442
                      desipramine + 51
                      imipramine + 133
                      methylphenidate 140
                      mianserin + 17
                      nefopam 1
                      nefopam hydrochloride 0
                      nisoxetine 2
                      nortriptyline 21
                      reserpine 120
                      tetrabenazine 2
                      tramadol 38
                      tramadol hydrochloride 0
                      venlafaxine + 181
    paths to the root