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ONTOLOGY REPORT - ANNOTATIONS
Term:EC 1.17.3.2 (xanthine oxidase) inhibitor
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Accession:CHEBI:35634 term browser browse the term
Definition:An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2).
Synonyms:related_synonym: EC 1.17.3.2 (xanthine oxidase) inhibitors;   EC 1.17.3.2 inhibitor;   EC 1.17.3.2 inhibitors;   Schardinger enzyme inhibitor;   Schardinger enzyme inhibitors;   hypoxanthine oxidase inhibitor;   hypoxanthine oxidase inhibitors;   hypoxanthine-xanthine oxidase inhibitor;   hypoxanthine-xanthine oxidase inhibitors;   hypoxanthine:oxygen oxidoreductase inhibitor;   hypoxanthine:oxygen oxidoreductase inhibitors;   xanthine oxidase inhibitor;   xanthine oxidase inhibitors;   xanthine oxidoreductase inhibitor;   xanthine oxidoreductase inhibitors;   xanthine:O2 oxidoreductase inhibitor;   xanthine:O2 oxidoreductase inhibitors;   xanthine:oxygen oxidoreductase inhibitor;   xanthine:oxygen oxidoreductase inhibitors;   xanthine:xanthine oxidase inhibitor;   xanthine:xanthine oxidase inhibitors

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6-formylpterin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bid BH3 interacting domain death agonist JBrowse link 4 153,439,812 153,465,247 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Casp8 caspase 8 JBrowse link 9 65,614,142 65,662,624 RGD:6480464
G Cycs cytochrome c, somatic JBrowse link 4 80,331,226 80,333,326 RGD:6480464
G Prkcd protein kinase C, delta JBrowse link 16 6,655,131 6,675,746 RGD:6480464
allopurinol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Abcg2 ATP binding cassette subfamily G member 2 JBrowse link 4 88,765,441 88,890,268 RGD:6480464
G Adipoq adiponectin, C1Q and collagen domain containing JBrowse link 11 81,330,845 81,344,488 RGD:6480464
G Adipor2 adiponectin receptor 2 JBrowse link 4 151,412,135 151,480,108 RGD:6480464
G Agt angiotensinogen JBrowse link 19 57,321,594 57,333,460 RGD:6480464
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 JBrowse link 1 238,222,689 238,264,381 RGD:6480464
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:6480464
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:6480464
G Casp1 caspase 1 JBrowse link 8 2,605,743 2,614,637 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cd36 CD36 molecule JBrowse link 4 14,150,309 14,191,498 RGD:6480464
G Cdh1 cadherin 1 JBrowse link 19 38,768,467 38,838,395 RGD:6480464
G Ckm creatine kinase, M-type JBrowse link 1 80,321,507 80,331,841 RGD:6480464
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:6480464
G Fasn fatty acid synthase JBrowse link 10 109,987,735 110,005,901 RGD:6480464
G Fn1 fibronectin 1 JBrowse link 9 78,900,111 78,969,018 RGD:6480464
G Fos Fos proto-oncogene, AP-1 transcription factor subunit JBrowse link 6 109,300,433 109,303,299 RGD:6480464
G Glul glutamate-ammonia ligase JBrowse link 13 71,331,052 71,340,207 RGD:6480464
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A JBrowse link 10 5,707,806 6,123,568 RGD:6480464
G Gsr glutathione-disulfide reductase JBrowse link 16 62,197,617 62,239,987 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Ifnb1 interferon beta 1 JBrowse link 5 106,865,192 106,865,746 RGD:6480464
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6480464
G Il18 interleukin 18 JBrowse link 8 55,009,666 55,016,286 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Insr insulin receptor JBrowse link 12 1,682,527 1,816,414 RGD:6480464
G Irs1 insulin receptor substrate 1 JBrowse link 9 88,033,668 88,086,488 RGD:6480464
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:6480464
G Lepr leptin receptor JBrowse link 5 120,503,475 120,682,281 RGD:6480464
G Lgals9 galectin 9 JBrowse link 10 64,737,022 64,760,195 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk14 mitogen activated protein kinase 14 JBrowse link 20 5,933,290 5,995,137 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Mpo myeloperoxidase JBrowse link 10 75,087,892 75,098,260 RGD:6480464
G Nfat5 nuclear factor of activated T-cells 5 JBrowse link 19 38,446,059 38,533,735 RGD:6480464
G Nfkbia NFKB inhibitor alpha JBrowse link 6 76,267,227 76,270,457 RGD:6480464
G Nlrp3 NLR family, pyrin domain containing 3 JBrowse link 10 45,884,324 45,918,290 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Nr1h3 nuclear receptor subfamily 1, group H, member 3 JBrowse link 3 80,004,130 80,014,197 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G Ptgs2 prostaglandin-endoperoxide synthase 2 JBrowse link 13 67,351,230 67,356,920 RGD:6480464
G Pycard PYD and CARD domain containing JBrowse link 1 199,438,029 199,439,062 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Slc22a1 solute carrier family 22 member 1 JBrowse link 1 48,273,639 48,300,645 RGD:6480464
G Slc22a12 solute carrier family 22 member 12 JBrowse link 1 221,910,787 221,919,277 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464
G Slc22a4 solute carrier family 22 member 4 JBrowse link 10 39,334,972 39,373,508 RGD:6480464
G Slc22a5 solute carrier family 22 member 5 JBrowse link 10 39,201,101 39,228,090 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc22a7 solute carrier family 22 member 7 JBrowse link 9 16,925,321 16,931,119 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464
G Slc2a9 solute carrier family 2 member 9 JBrowse link 14 77,067,537 77,192,702 RGD:6480464
G Slc5a3 solute carrier family 5 member 3 JBrowse link 11 32,229,366 32,231,812 RGD:6480464
G Srebf1 sterol regulatory element binding transcription factor 1 JBrowse link 10 46,570,996 46,593,021 RGD:6480464
G Srebf2 sterol regulatory element binding transcription factor 2 JBrowse link 7 123,381,082 123,438,605 RGD:6480464
G Stat1 signal transducer and activator of transcription 1 JBrowse link 9 54,287,540 54,327,958 RGD:6480464
G Stat3 signal transducer and activator of transcription 3 JBrowse link 10 88,790,401 88,842,263 RGD:6480464
G Tdo2 tryptophan 2,3-dioxygenase JBrowse link 2 180,897,059 180,914,919 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Txnip thioredoxin interacting protein JBrowse link 2 198,683,168 198,686,971 RGD:6480464
G Umod uromodulin JBrowse link 1 189,186,027 189,199,939 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464
alloxanthine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Alpl alkaline phosphatase, biomineralization associated JBrowse link 5 156,086,496 156,141,513 RGD:6480464
G Bglap bone gamma-carboxyglutamate protein JBrowse link 2 187,741,770 187,748,445 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Cxcl10 C-X-C motif chemokine ligand 10 JBrowse link 14 17,210,733 17,212,930 RGD:6480464
G Dek DEK proto-oncogene JBrowse link 17 17,965,872 17,987,836 RGD:6480464
G Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 JBrowse link 1 21,748,201 21,813,205 RGD:6480464
G Hmox1 heme oxygenase 1 JBrowse link 19 14,508,634 14,515,455 RGD:6480464
G Mmp9 matrix metallopeptidase 9 JBrowse link 3 161,413,410 161,421,473 RGD:6480464
G Slc22a12 solute carrier family 22 member 12 JBrowse link 1 221,910,787 221,919,277 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Xdh xanthine dehydrogenase JBrowse link 6 25,149,570 25,211,273 RGD:6480464
aspalathin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G F10 coagulation factor X JBrowse link 16 81,803,169 81,822,476 RGD:6480464
G F2 coagulation factor II JBrowse link 3 80,529,468 80,542,993 RGD:6480464
G F5 coagulation factor V JBrowse link 13 82,479,997 82,535,540 RGD:6480464
G F7 coagulation factor VII JBrowse link 16 81,824,610 81,834,923 RGD:6480464
G Icam1 intercellular adhesion molecule 1 JBrowse link 8 22,035,287 22,047,049 RGD:6480464
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Mapk1 mitogen activated protein kinase 1 JBrowse link 11 88,203,863 88,273,301 RGD:6480464
G Mapk3 mitogen activated protein kinase 3 JBrowse link 1 198,192,773 198,198,975 RGD:6480464
G Nos2 nitric oxide synthase 2 JBrowse link 10 66,188,290 66,221,621 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Sele selectin E JBrowse link 13 82,355,234 82,365,323 RGD:6480464
G Serpine1 serpin family E member 1 JBrowse link 12 22,641,104 22,651,482 RGD:6480464
G Tlr4 toll-like receptor 4 JBrowse link 5 82,587,424 82,601,056 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
G Vcam1 vascular cell adhesion molecule 1 JBrowse link 2 219,071,193 219,090,931 RGD:6480464
febuxostat term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bax BCL2 associated X, apoptosis regulator JBrowse link 1 101,451,801 101,457,207 RGD:6480464
G Bcl2 BCL2, apoptosis regulator JBrowse link 13 26,605,426 26,769,374 RGD:6480464
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:6480464
G Ccl2 C-C motif chemokine ligand 2 JBrowse link 10 69,412,065 69,413,863 RGD:6480464
G Got2 glutamic-oxaloacetic transaminase 2 JBrowse link 19 9,587,637 9,613,323 RGD:6480464
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta JBrowse link 16 74,177,233 74,230,809 RGD:6480464
G Nppb natriuretic peptide B JBrowse link 5 164,796,176 164,797,538 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
pedalitin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 JBrowse link 8 62,451,360 62,458,244 RGD:6480464
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 JBrowse link 1 147,713,879 147,814,410 RGD:6480464
purpurogallin term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 JBrowse link 1 213,511,892 213,522,195 RGD:6480464
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19728
    role 19675
      biological role 19673
        biochemical role 19178
          enzyme inhibitor 18079
            EC 1.* (oxidoreductase) inhibitor 16466
              EC 1.17.* (oxidoreductase acting on CH or CH2) inhibitor 517
                EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor 89
                  EC 1.17.3.2 (xanthine oxidase) inhibitor 89
                    6-formylpterin 5
                    8-azaadenine + 0
                    allopurinol + 65
                    alloxanthine + 11
                    aspalathin 16
                    febuxostat 10
                    pedalitin 2
                    procyanidin C1 0
                    purpurogallin 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.