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ONTOLOGY REPORT - ANNOTATIONS


Term:EC 3.5.2.6 (beta-lactamase) inhibitor
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Accession:CHEBI:35625 term browser browse the term
Definition:An EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor that interferes with the action of beta-lactamase (EC 3.5.2.6).
Synonyms:related_synonym: EC 3.5.2.6 (beta-lactamase) inhibitors;   EC 3.5.2.6 inhibitor;   EC 3.5.2.6 inhibitors;   ampicillinase inhibitor;   ampicillinase inhibitors;   beta-lactam hydrolase inhibitor;   beta-lactam hydrolase inhibitors;   beta-lactamase A, B, C inhibitor;   beta-lactamase A, B, C inhibitors;   beta-lactamase AME I inhibitor;   beta-lactamase AME I inhibitors;   beta-lactamase I-III inhibitor;   beta-lactamase I-III inhibitors;   beta-lactamase inhibitor;   beta-lactamase inhibitors;   cephalosporin-beta-lactamase inhibitor;   cephalosporin-beta-lactamase inhibitors;   cephalosporinase inhibitor;   cephalosporinase inhibitors;   exopenicillinase inhibitor;   exopenicillinase inhibitors;   neutrapen inhibitor;   neutrapen inhibitors;   penicillin amido-beta-lactamhydrolase inhibitor;   penicillin amido-beta-lactamhydrolase inhibitors;   penicillin beta-lactamase inhibitor;   penicillin beta-lactamase inhibitors;   penicillinase I, II inhibitor;   penicillinase I, II inhibitors;   penicillinase inhibitor;   penicillinase inhibitors


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ceftriaxone term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ace2 angiotensin I converting enzyme 2 JBrowse link X 32,050,734 32,095,860 RGD:6480464
G Actb actin, beta JBrowse link 12 13,715,843 13,718,813 RGD:6480464
G Bace1 beta-secretase 1 JBrowse link 8 50,140,092 50,162,388 RGD:6480464
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Dhfr dihydrofolate reductase JBrowse link 2 21,931,887 21,958,927 RGD:6480464
G Ece1 endothelin converting enzyme 1 JBrowse link 5 156,215,469 156,318,652 RGD:6480464
G Epo erythropoietin JBrowse link 12 22,274,828 22,278,268 RGD:6480464
G Ide insulin degrading enzyme JBrowse link 1 255,914,465 256,014,168 RGD:6480464
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Mme membrane metallo-endopeptidase JBrowse link 2 153,799,203 153,880,910 RGD:6480464
G Slc1a2 solute carrier family 1 member 2 JBrowse link 3 92,518,679 92,665,731 RGD:6480464
G Slc7a11 solute carrier family 7 member 11 JBrowse link 2 139,453,774 139,528,479 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464
salsalate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il6 interleukin 6 JBrowse link 4 3,043,231 3,047,807 RGD:6480464
G Nos3 nitric oxide synthase 3 JBrowse link 4 7,321,908 7,342,404 RGD:6480464
G Rela RELA proto-oncogene, NF-kB subunit JBrowse link 1 220,992,770 221,003,249 RGD:6480464
G Sod2 superoxide dismutase 2 JBrowse link 1 47,914,757 47,921,587 RGD:6480464
G Vegfa vascular endothelial growth factor A JBrowse link 9 17,340,341 17,355,681 RGD:6480464
tazobactam term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Il1b interleukin 1 beta JBrowse link 3 121,876,256 121,882,637 RGD:6480464
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:6480464

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      biological role 19716
        biochemical role 19207
          enzyme inhibitor 18084
            EC 3.* (hydrolase) inhibitor 17573
              EC 3.5.* (hydrolases acting on non-peptide C-N bonds) inhibitor 17455
                EC 3.5.2.* (non-peptide cyclic amide C-N hydrolase) inhibitor 18
                  EC 3.5.2.6 (beta-lactamase) inhibitor 18
                    3-carboxyphenyl phenylacetamidomethylphosphonate 0
                    7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-1H,10H-pyrano[4,3-b]chromene-9-carboxylic acid 0
                    7,8-dihydroxy-1-methoxy-3-methyl-10-oxo-4,10-dihydro-1H,3H-pyrano[4,3-b]chromene-9-carboxylic acid 0
                    7,8-dihydroxy-3-methyl-10-oxo-10H-chromeno[3,2-c]pyridine-9-carboxylic acid 0
                    avibactam 0
                    avibactam sodium + 0
                    ceftriaxone 13
                    clavulanic acid 0
                    potassium clavulanate + 0
                    salsalate 5
                    tazobactam 2
                    tazobactam sodium + 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.