azaspiro compound - Ontology Report - Rat Genome Database

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	azaspiro compound	go back to main search page
Accession:	CHEBI:35624	browse the term
Definition:	An azaspiro compound is a spiro compound in which at least one of the cyclic components is a nitrogen heterocyle.
Synonyms:	related_synonym:	azaspiro compounds

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Rat (878) Mouse (867) Human (881) Chinchilla (0) Bonobo (0) Dog (1) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (878)

13-desmethylspirolide C

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cholinergic receptor nicotinic alpha 4 subunit

multiple interactions

13-desmethylspirolide C binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]

NCBI chr 3:168,136,246...168,157,839
Ensembl chr 3:168,136,266...168,156,957

G

cholinergic receptor nicotinic alpha 7 subunit

multiple interactions

13-desmethylspirolide C binds to and results in decreased activity of CHRNA7 protein

NCBI chr 1:116,711,559...116,837,269
Ensembl chr 1:116,714,711...116,837,240

G

cholinergic receptor nicotinic beta 2 subunit

multiple interactions

13-desmethylspirolide C binds to and results in decreased activity of [CHRNA4 protein binds to CHRNB2 protein]

NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619

Azaspiracid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily G member 2

increases expression

azaspiracid results in increased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

ADP-dependent glucokinase

increases expression

azaspiracid results in increased expression of ADPGK mRNA

NCBI chr 8:59,699,400...59,727,352
Ensembl chr 8:59,699,388...59,727,351

G

alpha-fetoprotein

decreases expression

azaspiracid results in decreased expression of AFP mRNA

NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480

G

albumin

decreases expression

azaspiracid results in decreased expression of ALB mRNA

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aryl hydrocarbon receptor nuclear translocator

decreases expression

azaspiracid results in decreased expression of ARNT mRNA

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3

increases expression

azaspiracid results in increased expression of B3GNT3 mRNA

NCBI chr16:18,401,405...18,410,821
Ensembl chr16:18,401,405...18,410,766

G

Bcl2-like 11

decreases expression

azaspiracid results in decreased expression of BCL2L11 mRNA

NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068

G

basic helix-loop-helix family, member e40

increases expression

azaspiracid results in increased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

calumenin

increases expression

azaspiracid results in increased expression of CALU mRNA

NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593

G

caspase 3

increases activity

azaspiracid results in increased activity of CASP3 protein

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

CD44 molecule

increases expression

azaspiracid results in increased expression of CD44 mRNA

NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620

G

cadherin 1

increases expression
decreases uptake

azaspiracid results in increased expression of CDH1 protein modified form
azaspiracid results in decreased uptake of CDH1 protein modified form

PMID:17118960 PMID:20547569

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

CEA cell adhesion molecule 1

increases expression

azaspiracid results in increased expression of CEACAM1 mRNA

PMID:21853993 PMID:28939011

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

CEA cell adhesion molecule 6

increases expression

azaspiracid results in increased expression of CEACAM6 mRNA

NCBI chr 1:80,416,531...80,434,668
Ensembl chr 1:80,416,531...80,434,668

G

CCAAT/enhancer binding protein beta

increases expression

azaspiracid results in increased expression of CEBPB mRNA

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

cathepsin D

decreases metabolic processing

azaspiracid results in decreased metabolism of CTSD protein

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

DNA-damage-inducible transcript 4

increases expression

azaspiracid results in increased expression of DDIT4 mRNA

PMID:21853993 PMID:28939011

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

defensin beta 1

decreases expression

azaspiracid results in decreased expression of DEFB1 mRNA

NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604

G

7-dehydrocholesterol reductase

increases expression

azaspiracid results in increased expression of DHCR7 mRNA

NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055

G

DnaJ heat shock protein family (Hsp40) member C10

affects expression

azaspiracid affects the expression of DNAJC10 mRNA

NCBI chr 3:65,232,031...65,272,732
Ensembl chr 3:65,232,697...65,272,719

G

dual specificity phosphatase 6

increases expression

azaspiracid results in increased expression of DUSP6 mRNA

NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185

G

EDAR associated via death domain

increases expression

azaspiracid results in increased expression of EDARADD mRNA

NCBI chr17:85,866,629...85,910,612
Ensembl chr17:85,656,905...85,910,447

G

egl-9 family hypoxia-inducible factor 1

increases expression

azaspiracid results in increased expression of EGLN1 mRNA

NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777

G

egl-9 family hypoxia-inducible factor 3

increases expression

azaspiracid results in increased expression of EGLN3 mRNA

NCBI chr 6:71,650,297...71,675,766
Ensembl chr 6:71,650,297...71,675,766

G

early growth response 1

increases expression

azaspiracid results in increased expression of EGR1 mRNA

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

eukaryotic translation initiation factor 2 alpha kinase 3

increases expression

azaspiracid results in increased expression of EIF2AK3 mRNA

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

ELOVL fatty acid elongase 6

increases expression

azaspiracid results in increased expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

epithelial membrane protein 1

increases expression

azaspiracid results in increased expression of EMP1 mRNA

NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904

G

enolase 1

increases expression

azaspiracid results in increased expression of ENO1 mRNA

NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336

G

enolase 2

increases expression

azaspiracid results in increased expression of ENO2 mRNA

NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980

G

endoplasmic reticulum to nucleus signaling 1

decreases expression

azaspiracid results in decreased expression of ERN1 mRNA

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

farnesyl diphosphate farnesyl transferase 1

increases expression

azaspiracid results in increased expression of FDFT1 mRNA

NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287

G

farnesyl diphosphate synthase

increases expression

azaspiracid results in increased expression of FDPS mRNA

NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776

G

fibrinogen alpha chain

decreases expression

azaspiracid results in decreased expression of FGA mRNA

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

G

fibrinogen beta chain

decreases expression

azaspiracid results in decreased expression of FGB mRNA

NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979

G

fibrinogen gamma chain

decreases expression

azaspiracid results in decreased expression of FGG mRNA

NCBI chr 2:168,354,880...168,362,325
Ensembl chr 2:168,355,013...168,362,322

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression

azaspiracid results in increased expression of FOS mRNA

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

glypican 5

decreases expression

azaspiracid results in decreased expression of GPC5 mRNA

NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282

G

glucose-6-phosphate isomerase

affects expression

azaspiracid affects the expression of GPI mRNA

NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086

G

glutathione S-transferase alpha 1

decreases expression

azaspiracid results in decreased expression of GSTA1 mRNA

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 2

decreases expression

azaspiracid results in decreased expression of GSTA2 mRNA

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

glutathione S-transferase alpha 5

decreases expression

azaspiracid results in decreased expression of GSTA5 mRNA

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

H1.4 linker histone, cluster member

decreases expression

azaspiracid results in decreased expression of H1-4 mRNA

NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403

G

hypoxia inducible factor 1 subunit alpha

decreases expression

azaspiracid results in decreased expression of HIF1A mRNA

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

histone cluster 1 H2A family like 1

decreases expression

azaspiracid results in decreased expression of H2AC6 mRNA

NCBI chr17:42,707,954...42,708,420

G

hexokinase 2

increases expression

azaspiracid results in increased expression of HK2 mRNA

NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530

G

hexokinase domain containing 1

increases expression

azaspiracid results in increased expression of HKDC1 mRNA

NCBI chr20:30,335,322...30,373,792
Ensembl chr20:30,335,628...30,373,867

G

3-hydroxy-3-methylglutaryl-CoA reductase

increases expression

azaspiracid results in increased expression of HMGCR mRNA

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

3-hydroxy-3-methylglutaryl-CoA synthase 1

increases expression

azaspiracid results in increased expression of HMGCS1 mRNA

NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100

G

homeo box B6

increases expression

azaspiracid results in increased expression of HOXB6 mRNA

NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449

G

homeo box B9

increases expression

azaspiracid results in increased expression of HOXB9 mRNA

NCBI chr10:81,237,312...81,240,818
Ensembl chr10:81,237,312...81,240,818

G

isopentenyl-diphosphate delta isomerase 1

increases expression

azaspiracid results in increased expression of IDI1 mRNA

NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

azaspiracid results in increased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

potassium voltage-gated channel subfamily H member 2

multiple interactions

azaspiracid binds to and results in decreased activity of KCNH2 protein

NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008

G

laminin subunit alpha 1

decreases expression

azaspiracid results in decreased expression of LAMA1 mRNA

NCBI chr 9:107,692,770...107,816,847
Ensembl chr 9:107,692,770...107,817,478

G

low density lipoprotein receptor

increases expression

azaspiracid results in increased expression of LDLR mRNA

NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580

G

lamin B1

decreases expression

azaspiracid results in decreased expression of LMNB1 mRNA

NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502

G

lipin 1

increases expression

azaspiracid results in increased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

mitogen activated protein kinase kinase 3

decreases expression

azaspiracid results in decreased expression of MAP2K3 mRNA

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

G

mitogen-activated protein kinase 8

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein]; Amiloride inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein]; azaspiracid results in increased phosphorylation of and affects the localization of MAPK8 protein

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 9

multiple interactions

4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK9 protein]; Amiloride inhibits the reaction [azaspiracid results in increased phosphorylation of and affects the localization of MAPK9 protein]; azaspiracid results in increased phosphorylation of and affects the localization of MAPK9 protein

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

microsomal glutathione S-transferase 1

increases expression

azaspiracid results in increased expression of MGST1 mRNA

NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892

G

microsomal glutathione S-transferase 2

increases expression

azaspiracid results in increased expression of MGST2 mRNA

NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828

G

matrix metallopeptidase 1

increases expression

azaspiracid results in increased expression of MMP1 mRNA

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

G

metallothionein 1

increases expression

azaspiracid results in increased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

metallothionein 1, pseudogene 3

increases expression

azaspiracid results in increased expression of MT1E mRNA

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

G

metallothionein 2A

increases expression

azaspiracid results in increased expression of MT2A mRNA

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

G

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase

increases expression

azaspiracid results in increased expression of MTHFD2 mRNA

NCBI chr 4:115,811,135...115,822,663
Ensembl chr 4:115,811,139...115,822,608

G

mevalonate kinase

increases expression

azaspiracid results in increased expression of MVK mRNA

NCBI chr12:42,141,391...42,158,893
Ensembl chr12:42,141,384...42,158,882

G

MYC proto-oncogene, bHLH transcription factor

increases expression

azaspiracid results in increased expression of MYC mRNA

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

G

odd-skipped related transciption factor 2

decreases expression

azaspiracid results in decreased expression of OSR2 mRNA

NCBI chr 7:66,487,841...66,495,003
Ensembl chr 7:66,487,839...66,495,224

G

pyruvate dehydrogenase E1 subunit beta

increases expression

azaspiracid results in increased expression of PDHB mRNA

NCBI chr15:16,752,561...16,758,503
Ensembl chr15:16,750,980...16,758,500

G

protein disulfide isomerase family A, member 3

increases expression

azaspiracid results in increased expression of PDIA3 mRNA

NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236

G

phosphofructokinase, platelet

increases expression

azaspiracid results in increased expression of PFKP mRNA

NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018

G

phosphoglycerate mutase 1

increases expression

azaspiracid results in increased expression of PGAM1 mRNA

NCBI chr 1:240,723,832...240,731,443
Ensembl chr 1:240,723,920...240,738,452

G

phosphoglycerate kinase 1

increases expression

azaspiracid results in increased expression of PGK1 mRNA

NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418

G

protein phosphatase 1, regulatory subunit 15A

increases expression

azaspiracid results in increased expression of PPP1R15A mRNA

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

G

prolactin receptor

decreases uptake

azaspiracid results in decreased uptake of PRLR protein

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

G

ribosomal protein S27a

increases expression

azaspiracid results in increased expression of RPS27A mRNA

NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011

G

stearoyl-CoA desaturase

increases expression

azaspiracid results in increased expression of SCD mRNA

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

sucrase-isomaltase

decreases expression

azaspiracid results in decreased expression of SI mRNA

NCBI chr 2:157,505,893...157,586,228
Ensembl chr 2:157,506,342...157,585,260

G

solute carrier family 2 member 1

increases expression

azaspiracid results in increased expression of SLC2A1 mRNA

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 7 member 11

increases expression

azaspiracid results in increased expression of SLC7A11 mRNA

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

serine palmitoyltransferase, long chain base subunit 3

decreases expression

azaspiracid results in decreased expression of SPTLC3 mRNA

NCBI chr 3:126,847,878...126,978,010
Ensembl chr 3:126,847,878...126,978,010

G

serine palmitoyltransferase, small subunit B

decreases expression

azaspiracid results in decreased expression of SPTSSB mRNA

NCBI chr 2:154,133,728...154,162,127
Ensembl chr 2:154,133,733...154,163,120

G

squalene epoxidase

increases expression

azaspiracid results in increased expression of SQLE mRNA

NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618

G

sterol regulatory element binding transcription factor 1

increases expression

azaspiracid results in increased expression of SREBF1 mRNA

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

G

StAR-related lipid transfer domain containing 4

increases expression

azaspiracid results in increased expression of STARD4 mRNA

NCBI chr18:24,814,683...24,830,024
Ensembl chr18:24,817,107...24,830,024

G

TIMP metallopeptidase inhibitor 1

increases expression

azaspiracid results in increased expression of TIMP1 protein

NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664

G

tensin 4

increases expression

azaspiracid results in increased expression of TNS4 mRNA

NCBI chr10:84,021,965...84,041,346
Ensembl chr10:84,021,966...84,041,346

G

triosephosphate isomerase 1

increases expression

azaspiracid results in increased expression of TPI1 mRNA

NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541

G

tribbles pseudokinase 3

increases expression

azaspiracid results in increased expression of TRIB3 mRNA

PMID:21853993 PMID:28939011

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

tubulin, beta 3 class III

increases expression

azaspiracid results in increased expression of TUBB3 mRNA

NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243

G

ubiquitin B

increases expression

azaspiracid results in increased expression of UBB mRNA

NCBI chr10:47,247,630...47,249,335
Ensembl chr10:47,245,637...47,249,333

G

ubiquitin C

increases expression

azaspiracid results in increased expression of UBC mRNA

NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925

G

vascular endothelial growth factor A

increases expression

azaspiracid results in increased expression of VEGFA mRNA

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

Brevianamide A

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily F member 1

increases expression

brevianamide A results in increased expression of ABCF1 mRNA

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

increases expression

brevianamide A results in increased expression of AIMP1 mRNA

NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728

G

C-C motif chemokine ligand 11

increases expression

brevianamide A results in increased expression of CCL11 mRNA

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

G

C-C motif chemokine ligand 12

decreases expression
increases expression

brevianamide A results in decreased expression of CCL12 mRNA
brevianamide A results in increased expression of CCL12 mRNA

NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780

G

C-C motif chemokine ligand 19

increases expression

brevianamide A results in increased expression of CCL19 mRNA

NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308

G

C-C motif chemokine ligand 2

decreases expression

brevianamide A results in decreased expression of CCL2 mRNA

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

decreases expression
increases expression

brevianamide A results in decreased expression of CCL20 mRNA
brevianamide A results in increased expression of CCL20 mRNA

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 24

increases expression

brevianamide A results in increased expression of CCL24 mRNA

NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893

G

C-C motif chemokine ligand 25

increases expression

brevianamide A results in increased expression of CCL25 mRNA

NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554

G

C-C motif chemokine ligand 4

decreases expression

brevianamide A results in decreased expression of CCL4 mRNA

NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231

G

C-C motif chemokine ligand 5

increases expression

brevianamide A results in increased expression of CCL5 mRNA

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

C-C motif chemokine ligand 7

decreases expression

brevianamide A results in decreased expression of CCL7 mRNA

NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303

G

C-C motif chemokine receptor 10

increases expression

brevianamide A results in increased expression of CCR10 mRNA

NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988

G

C-C motif chemokine receptor 2

increases expression

brevianamide A results in increased expression of CCR2 mRNA

NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100

G

C-C motif chemokine receptor 3

increases expression

brevianamide A results in increased expression of CCR3 mRNA

NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990

G

C-C motif chemokine receptor 4

increases expression

brevianamide A results in increased expression of CCR4 mRNA

NCBI chr 8:114,176,291...114,182,033
Ensembl chr 8:114,176,974...114,178,056

G

C-C motif chemokine receptor 6

increases expression

brevianamide A results in increased expression of CCR6 mRNA

NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603

G

C-C motif chemokine receptor 7

increases expression

brevianamide A results in increased expression of CCR7 mRNA

NCBI chr10:84,098,193...84,108,309
Ensembl chr10:84,097,381...84,108,309

G

C-C motif chemokine receptor 9

increases expression

brevianamide A results in increased expression of CCR9 mRNA

NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969

G

CD40 ligand

increases expression

brevianamide A results in increased expression of CD40LG mRNA

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

G

C-X3-C motif chemokine ligand 1

increases expression

brevianamide A results in increased expression of CX3CL1 mRNA

NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833

G

C-X-C motif chemokine ligand 12

increases expression

brevianamide A results in increased expression of CXCL12 mRNA

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 13

increases expression

brevianamide A results in increased expression of CXCL13 mRNA

NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933

G

C-X-C motif chemokine ligand 2

increases expression

brevianamide A results in increased expression of CXCL2 protein

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

decreases expression

brevianamide A results in decreased expression of CXCL1 mRNA

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 6

decreases expression
increases expression

brevianamide A results in decreased expression of CXCL5 mRNA
brevianamide A results in increased expression of CXCL5 mRNA

NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093

G

C-X-C motif chemokine receptor 2

increases expression

brevianamide A results in increased expression of CXCR2 mRNA

NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425

G

C-X-C motif chemokine receptor 3

increases expression

brevianamide A results in increased expression of CXCR3 mRNA

NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969

G

C-X-C motif chemokine receptor 5

increases expression

brevianamide A results in increased expression of CXCR5 mRNA

NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893

G

interleukin 10 receptor subunit alpha

increases expression

brevianamide A results in increased expression of IL10RA mRNA

NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061

G

interleukin 10 receptor subunit beta

increases expression

brevianamide A results in increased expression of IL10RB mRNA

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

G

interleukin 11

increases expression

brevianamide A results in increased expression of IL11 mRNA

NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129

G

interleukin 13

increases expression

brevianamide A results in increased expression of IL13 mRNA

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 13 receptor subunit alpha 1

increases expression

brevianamide A results in increased expression of IL13RA1 mRNA

NCBI chr X:115,348,822...115,408,682
Ensembl chr X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681

G

interleukin 16

increases expression

brevianamide A results in increased expression of IL16 mRNA

NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130

G

interleukin 18

increases expression

brevianamide A results in increased expression of IL18 mRNA

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 receptor type 1

increases expression

brevianamide A results in increased expression of IL1R1 mRNA

NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937

G

interleukin 2 receptor subunit beta

increases expression

brevianamide A results in increased expression of IL2RB mRNA

NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054

G

interleukin 2 receptor subunit gamma

increases expression

brevianamide A results in increased expression of IL2RG mRNA

NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823

G

interleukin 6 receptor

increases expression

brevianamide A results in increased expression of IL6RA mRNA

NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536

G

interleukin 6 cytokine family signal transducer

increases expression

brevianamide A results in increased expression of IL6ST mRNA

NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936

G

lymphotoxin beta

increases expression

brevianamide A results in increased expression of LTB mRNA

NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381

G

macrophage migration inhibitory factor

increases expression

brevianamide A results in increased expression of MIF mRNA

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

G

platelet factor 4

increases expression

brevianamide A results in increased expression of PF4 mRNA

NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365

G

transforming growth factor, beta 1

increases expression

brevianamide A results in increased expression of TGFB1 mRNA

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

tumor necrosis factor

decreases expression
increases expression

brevianamide A results in decreased expression of TNF mRNA
brevianamide A results in increased expression of TNF mRNA; brevianamide A results in increased expression of TNF protein

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF receptor superfamily member 1A

increases expression

brevianamide A results in increased expression of TNFRSF1A mRNA

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

G

TNF receptor superfamily member 1B

increases expression

brevianamide A results in increased expression of TNFRSF1B mRNA

NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206

buspirone

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

aminoadipate-semialdehyde synthase

increases expression

Buspirone results in increased expression of AASS mRNA

NCBI chr 4:51,606,461...51,663,136
Ensembl chr 4:51,606,462...51,663,136

G

ATP binding cassette subfamily A member 1

increases expression

Buspirone results in increased expression of ABCA1 mRNA

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily C member 2

decreases expression

Buspirone results in decreased expression of ABCC2 mRNA

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily F member 1

decreases expression

Buspirone results in decreased expression of ABCF1 mRNA

NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433

G

ATP binding cassette subfamily G member 2

decreases expression

Buspirone results in decreased expression of ABCG2 mRNA

NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409

G

abhydrolase domain containing 14b

increases expression

Buspirone results in increased expression of ABHD14B mRNA

NCBI chr 8:107,087,157...107,092,122
Ensembl chr 8:107,088,069...107,092,119

G

ankyrin repeat and BTB domain containing 1

increases expression

Buspirone results in increased expression of ABTB1 mRNA

NCBI chr 4:121,299,302...121,305,667
Ensembl chr 4:121,299,304...121,305,620

G

acetyl-CoA acyltransferase 2

increases expression

Buspirone results in increased expression of ACAA2 mRNA

NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249

G

acetyl-CoA carboxylase alpha

decreases expression

Buspirone results in decreased expression of ACACA mRNA

NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457

G

acyl-CoA binding domain containing 4

increases expression

Buspirone results in increased expression of ACBD4 mRNA

NCBI chr10:88,048,058...88,062,612
Ensembl chr10:88,048,108...88,058,500

G

ATP citrate lyase

decreases expression

Buspirone results in decreased expression of ACLY mRNA

NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320

G

acyl-CoA synthetase family member 2

decreases expression

Buspirone results in decreased expression of ACSF2 mRNA

NCBI chr10:79,504,510...79,546,714
Ensembl chr10:79,504,511...79,546,673

G

acyl-CoA synthetase long-chain family member 3

decreases expression

Buspirone results in decreased expression of ACSL3 mRNA

NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627

G

acyl-CoA synthetase long-chain family member 4

increases expression

Buspirone results in increased expression of ACSL4 mRNA

NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427

G

acyl-CoA synthetase long-chain family member 5

decreases expression

Buspirone results in decreased expression of ACSL5 mRNA

NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607

G

actin, beta

decreases expression

Buspirone results in decreased expression of ACTB mRNA

NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877

G

actin, gamma 1

decreases expression

Buspirone results in decreased expression of ACTG1 mRNA

NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232

G

actinin, alpha 1

decreases expression

Buspirone results in decreased expression of ACTN1 mRNA

NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251

G

aminoacylase 1

decreases expression

Buspirone results in decreased expression of ACY1 mRNA

NCBI chr 8:107,072,354...107,077,756
Ensembl chr 8:107,072,358...107,077,682

G

ADAMTS-like 4

increases expression

Buspirone results in increased expression of ADAMTSL4 mRNA

NCBI chr 2:183,235,634...183,247,091
Ensembl chr 2:183,235,646...183,246,848

G

adenylate cyclase 6

increases expression

Buspirone results in increased expression of ADCY6 mRNA

NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754

G

adiponectin receptor 2

decreases expression

Buspirone results in decreased expression of ADIPOR2 mRNA

NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355

G

adrenoceptor alpha 1A

multiple interactions

Buspirone binds to and results in decreased activity of ADRA1A protein

NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500

G

adrenoceptor alpha 1D

multiple interactions

Buspirone binds to and results in increased activity of ADRA1D protein

NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354

G

agmatinase

increases expression

Buspirone results in increased expression of AGMAT mRNA

NCBI chr 5:154,043,665...154,074,278
Ensembl chr 5:154,060,151...154,074,276

G

adenosylhomocysteinase

increases expression

Buspirone results in increased expression of AHCY mRNA

NCBI chr 3:143,569,134...143,584,359
Ensembl chr 3:143,569,094...143,584,393

G

allograft inflammatory factor 1

decreases expression

Buspirone results in decreased expression of AIF1 mRNA

NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668

G

androgen-induced 1

increases expression

Buspirone results in increased expression of AIG1 mRNA

NCBI chr 1:8,046,430...8,269,276
Ensembl chr 1:8,046,430...8,269,084

G

adenylate kinase 4

decreases expression

Buspirone results in decreased expression of AK4 mRNA

NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618

G

A-kinase anchoring protein 8 like

increases expression

Buspirone results in increased expression of AKAP8L mRNA

NCBI chr 7:11,332,671...11,362,287
Ensembl chr 7:11,332,672...11,362,275

G

aldo-keto reductase family 7 member A3

decreases expression

Buspirone results in decreased expression of AKR7A3 mRNA

NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394

G

aldehyde dehydrogenase 1 family, member B1

decreases expression

Buspirone results in decreased expression of ALDH1B1 mRNA

NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378

G

alkB homolog 7

increases expression

Buspirone results in increased expression of ALKBH7 mRNA

NCBI chr 9:1,838,886...1,841,044
Ensembl chr 9:1,838,811...1,841,044

G

ANKH inorganic pyrophosphate transport regulator

decreases expression

Buspirone results in decreased expression of ANKH mRNA

NCBI chr 2:78,153,027...78,280,181
Ensembl chr 2:78,153,026...78,280,187

G

ankyrin repeat and KH domain containing 1

increases expression

Buspirone results in increased expression of ANKHD1-EIF4EBP3 mRNA

NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024

G

ankyrin repeat domain 46

increases expression

Buspirone results in increased expression of ANKRD46 mRNA

NCBI chr 7:67,647,202...67,668,180
Ensembl chr 7:67,647,204...67,668,132

G

ANTXR cell adhesion molecule 2

increases expression

Buspirone results in increased expression of ANTXR2 mRNA

NCBI chr14:11,541,718...11,682,110
Ensembl chr14:11,541,772...11,682,094

G

annexin A3

decreases expression

Buspirone results in decreased expression of ANXA3 mRNA

NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617

G

annexin A5

decreases expression

Buspirone results in decreased expression of ANXA5 mRNA

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

apolipoprotein B

decreases expression

Buspirone results in decreased expression of APOB mRNA

NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497

G

apolipoprotein L7b

decreases expression

Buspirone results in decreased expression of APOL7B mRNA

NCBI chr 7:109,118,559...109,149,798
Ensembl chr 7:109,131,064...109,147,649

G

apolipoprotein O

decreases expression

Buspirone results in decreased expression of APOO mRNA

NCBI chr X:59,157,971...59,262,940
Ensembl chr X:59,158,049...59,262,940

G

apolipoprotein O-like

decreases expression

Buspirone results in decreased expression of APOOL mRNA

NCBI chr X:77,377,723...77,443,672
Ensembl chr X:77,377,781...77,443,900

G

amyloid beta precursor protein

decreases expression

Buspirone results in decreased expression of APP mRNA

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

Rho GTPase activating protein 24

decreases expression

Buspirone results in decreased expression of ARHGAP24 mRNA

NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823

G

Rho GDP dissociation inhibitor beta

decreases expression

Buspirone results in decreased expression of ARHGDIB mRNA

NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658

G

ADP-ribosylation factor like GTPase 1

decreases expression

Buspirone results in decreased expression of ARL1 mRNA

NCBI chr 7:23,120,004...23,131,173
Ensembl chr 7:23,119,589...23,131,898

G

ADP-ribosylation factor like GTPase 4A

increases expression

Buspirone results in increased expression of ARL4A mRNA

NCBI chr 6:57,079,496...57,084,156
Ensembl chr 6:57,078,812...57,085,066

G

ADP-ribosylation factor like GTPase 6 interacting protein 1

decreases expression

Buspirone results in decreased expression of ARL6IP1 mRNA

NCBI chr 1:172,430,475...172,439,990
Ensembl chr 1:172,430,489...172,439,994

G

acidic residue methyltransferase 1

decreases expression

Buspirone results in decreased expression of ARMT1 mRNA

NCBI chr 1:40,894,558...40,918,302
Ensembl chr 1:40,894,550...40,918,302

G

arylsulfatase B

decreases expression

Buspirone results in decreased expression of ARSB mRNA

NCBI chr 2:25,002,210...25,162,675
Ensembl chr 2:25,002,346...25,162,671

G

arsenite methyltransferase

increases expression

Buspirone results in increased expression of AS3MT mRNA

NCBI chr 1:245,595,939...245,628,921
Ensembl chr 1:245,596,108...245,627,872

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

decreases expression

Buspirone results in decreased expression of ASAP2 mRNA

NCBI chr 6:40,658,201...40,821,017
Ensembl chr 6:40,657,880...40,820,975

G

asialoglycoprotein receptor 1

increases expression

Buspirone results in increased expression of ASGR1 mRNA

NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631

G

asparaginase

increases expression

Buspirone results in increased expression of ASPG mRNA

NCBI chr 6:131,176,727...131,196,268
Ensembl chr 6:131,176,874...131,196,268

G

activating transcription factor 5

increases expression

Buspirone results in increased expression of ATF5 mRNA

NCBI chr 1:95,295,602...95,299,755
Ensembl chr 1:95,295,610...95,299,707

G

autophagy related 2B

increases expression

Buspirone results in increased expression of ATG2B mRNA

NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015

G

atlastin GTPase 2

increases expression

Buspirone results in increased expression of ATL2 mRNA

NCBI chr 6:15,139,071...15,180,421
Ensembl chr 6:15,139,044...15,180,421

G

ATPase phospholipid transporting 11C

increases expression

Buspirone results in increased expression of ATP11C mRNA

NCBI chr X:138,564,459...138,752,116
Ensembl chr X:138,565,836...138,751,204

G

ATPase H+ transporting V0 subunit B

increases expression

Buspirone results in increased expression of ATP6V0B mRNA

NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401

G

ATPase H+ transporting V0 subunit e1

increases expression

Buspirone results in increased expression of ATP6V0E1 mRNA

NCBI chr10:16,479,656...16,502,732
Ensembl chr10:16,479,567...16,524,434

G

ATPase H+ transporting V1 subunit G1

increases expression

Buspirone results in increased expression of ATP6V1G1 mRNA

NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463

G

Axl receptor tyrosine kinase

decreases expression

Buspirone results in decreased expression of AXL mRNA

NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265

G

antizyme inhibitor 1

decreases expression

Buspirone results in decreased expression of AZIN1 mRNA

NCBI chr 7:69,654,773...69,681,578
Ensembl chr 7:69,654,663...69,681,578

G

beta-1,4-N-acetyl-galactosaminyl transferase 1

increases expression

Buspirone results in increased expression of B4GALNT1 mRNA

NCBI chr 7:62,988,429...62,996,190
Ensembl chr 7:62,988,930...62,996,190

G

BAR/IMD domain containing adaptor protein 2 like 1

increases expression

Buspirone results in increased expression of BAIAP2L1 mRNA

NCBI chr12:10,250,434...10,339,937
Ensembl chr12:10,250,473...10,339,928

G

biglycan

decreases expression

Buspirone results in decreased expression of BGN mRNA

NCBI chr X:151,197,296...151,209,458
Ensembl chr X:151,197,273...151,209,461

G

basic helix-loop-helix family, member e40

decreases expression

Buspirone results in decreased expression of BHLHE40 mRNA

NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774

G

biliverdin reductase B

increases expression

Buspirone results in increased expression of BLVRB mRNA

NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375

G

BCL2 interacting protein 3

increases expression

Buspirone results in increased expression of BNIP3 mRNA

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

bolA family member 1

increases expression

Buspirone results in increased expression of BOLA1 mRNA

NCBI chr 2:183,758,515...183,771,445
Ensembl chr 2:183,758,441...183,781,576

G

bisphosphoglycerate mutase

decreases expression

Buspirone results in decreased expression of BPGM mRNA

NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581

G

BTG anti-proliferation factor 2

decreases expression

Buspirone results in decreased expression of BTG2 mRNA

NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628

G

similar to human chromosome 17 open reading frame 58

increases expression

Buspirone results in increased expression of C10H17ORF58 mRNA

NCBI chr10:91,972,938...91,977,606
Ensembl chr10:91,972,410...91,977,602

G

complement C1q B chain

decreases expression

Buspirone results in decreased expression of C1QB mRNA

NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407

G

similar to human chromosome 1 open reading frame 50

increases expression

Buspirone results in increased expression of C5H1ORF50 mRNA

NCBI chr 5:132,837,135...132,841,744
Ensembl chr 5:132,836,506...132,841,762

G

complement C5 like 1

increases expression

Buspirone results in increased expression of C5L1 mRNA

NCBI chr 3:18,401,716...18,420,064
Ensembl chr 3:18,404,899...18,420,054

G

complement C6

decreases expression

Buspirone results in decreased expression of C6 mRNA

NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275

G

complement C8 gamma chain

increases expression

Buspirone results in increased expression of C8G mRNA

NCBI chr 3:8,320,503...8,322,087
Ensembl chr 3:8,305,920...8,323,495

G

similar to human chromosome 11 open reading frame 54

decreases expression

Buspirone results in decreased expression of C8H11ORF54 mRNA

NCBI chr 8:12,123,839...12,146,412
Ensembl chr 8:12,123,823...12,146,473

G

similar to human chromosome 11 open reading frame 65

increases expression

Buspirone results in increased expression of C8H11ORF65 mRNA

NCBI chr 8:53,796,033...53,825,277
Ensembl chr 8:53,796,366...53,824,748

G

similar to human chromosome 11 open reading frame 71

increases expression

Buspirone results in increased expression of C8H11ORF71 mRNA

NCBI chr 8:48,838,556...48,838,970
Ensembl chr 8:48,838,100...48,842,270

G

similar to human chromosome 15 open reading frame 61

increases expression

Buspirone results in increased expression of C8H15ORF61 mRNA

NCBI chr 8:63,868,125...63,872,863
Ensembl chr 8:63,868,125...63,872,751

G

caldesmon 1

decreases expression

Buspirone results in decreased expression of CALD1 mRNA

NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932

G

calmodulin 1

decreases expression

Buspirone results in decreased expression of CALM1 mRNA

NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227

G

calmodulin 2

decreases expression

Buspirone results in decreased expression of CALM2 mRNA

NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287

G

calreticulin

decreases expression

Buspirone results in decreased expression of CALR mRNA

NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414

G

cyclase associated actin cytoskeleton regulatory protein 1

decreases expression

Buspirone results in decreased expression of CAP1 mRNA

NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769

G

carbonic anhydrase 3

decreases expression

Buspirone results in decreased expression of CAR3 mRNA

NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280

G

carbonic anhydrase 5A

increases expression

Buspirone results in increased expression of CAR5A mRNA

NCBI chr19:49,973,092...50,002,948
Ensembl chr19:49,973,107...50,002,906

G

caspase 1

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased cleavage of CASP1 protein]

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 3

decreases expression

Buspirone results in decreased expression of CASP3 mRNA

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 6

increases expression

Buspirone results in increased expression of CASP6 mRNA

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 7

decreases expression

Buspirone results in decreased expression of CASP7 mRNA

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

catalase

increases expression

Buspirone results in increased expression of CAT protein

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

carbonyl reductase 4

increases expression

Buspirone results in increased expression of CBR4 mRNA

NCBI chr16:28,629,928...28,684,230
Ensembl chr16:28,617,224...28,645,712

G

coiled-coil domain containing 6

increases expression

Buspirone results in increased expression of CCDC6 mRNA

NCBI chr20:18,432,177...18,528,186
Ensembl chr20:18,433,695...18,528,658

G

coiled-coil domain containing 80

decreases expression

Buspirone results in decreased expression of CCDC80 mRNA

NCBI chr11:55,685,165...55,718,827
Ensembl chr11:55,685,872...55,719,137

G

C-C motif chemokine ligand 9

decreases expression

Buspirone results in decreased expression of CCL6 mRNA

NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369

G

cyclin B2

decreases expression

Buspirone results in decreased expression of CCNB2 mRNA

NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874

G

cyclin D1

decreases expression

Buspirone results in decreased expression of CCND1 mRNA

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

CD164 molecule

decreases expression

Buspirone results in decreased expression of CD164 mRNA

NCBI chr20:45,024,051...45,035,628
Ensembl chr20:45,023,973...45,035,634

G

Cd5 molecule-like

decreases expression

Buspirone results in decreased expression of CD5L mRNA

NCBI chr 2:172,791,007...172,802,018
Ensembl chr 2:172,790,934...172,829,753

G

Cd68 molecule

decreases expression

Buspirone results in decreased expression of CD68 mRNA

NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697

G

CD74 molecule

decreases expression

Buspirone results in decreased expression of CD74 mRNA

NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003

G

cell division cycle 20

decreases expression

Buspirone results in decreased expression of CDC20 mRNA

NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512

G

cyclin-dependent kinase 1

decreases expression

Buspirone results in decreased expression of CDK1 mRNA

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase inhibitor 2C

decreases expression

Buspirone results in decreased expression of CDKN2C mRNA

NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278

G

cyclin-dependent kinase inhibitor 3

decreases expression

Buspirone results in decreased expression of CDKN3 mRNA

NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945

G

CEA cell adhesion molecule 1

decreases expression

Buspirone results in decreased expression of CEACAM1 mRNA

NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992

G

CEA cell adhesion molecule 4

decreases expression

Buspirone results in decreased expression of CEACAM10 mRNA

NCBI chr 1:80,376,667...80,382,943
Ensembl chr 1:80,376,648...80,382,915

G

centrosomal protein 20

decreases expression

Buspirone results in decreased expression of CEP20 mRNA

NCBI chr10:714,051...736,826
Ensembl chr10:714,151...736,837

G

cofilin 1

decreases expression

Buspirone results in decreased expression of CFL1 mRNA

NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587

G

cingulin

decreases expression

Buspirone results in decreased expression of CGN mRNA

NCBI chr 2:182,308,389...182,335,747
Ensembl chr 2:182,308,714...182,334,645

G

choline phosphotransferase 1

increases expression

Buspirone results in increased expression of CHPT1 mRNA

NCBI chr 7:22,866,455...22,915,111
Ensembl chr 7:22,863,027...22,915,103

G

churchill domain containing 1

increases expression

Buspirone results in increased expression of CHURC1 mRNA

NCBI chr 6:95,464,488...95,485,208
Ensembl chr 6:95,470,683...95,619,586

G

CDC28 protein kinase regulatory subunit 2

decreases expression

Buspirone results in decreased expression of CKS2 mRNA

NCBI chr17:13,570,611...13,575,770

G

C-type lectin domain family 4, member F

decreases expression

Buspirone results in decreased expression of CLEC4F mRNA

NCBI chr 4:116,129,023...116,138,744
Ensembl chr 4:116,129,023...116,138,775

G

chloride intracellular channel 1

decreases expression

Buspirone results in decreased expression of CLIC1 mRNA

NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712

G

ClpB family mitochondrial disaggregase

decreases expression

Buspirone results in decreased expression of CLPB mRNA

NCBI chr 1:156,028,740...156,158,183
Ensembl chr 1:156,028,930...156,168,788

G

clathrin, light chain B

increases expression

Buspirone results in increased expression of CLTB mRNA

NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169

G

CKLF-like MARVEL transmembrane domain containing 6

decreases expression

Buspirone results in decreased expression of CMTM6 mRNA

NCBI chr 8:114,422,934...114,441,034
Ensembl chr 8:114,422,921...114,441,033

G

cyclin Pas1/PHO80 domain containing 1

increases expression

Buspirone results in increased expression of CNPPD1 mRNA

NCBI chr 9:76,633,475...76,640,164
Ensembl chr 9:76,633,477...76,640,188

G

cannabinoid receptor 1

affects response to substance

CNR1 affects the susceptibility to Buspirone

NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099

G

cordon-bleu WH2 repeat protein-like 1

increases expression

Buspirone results in increased expression of COBLL1 mRNA

NCBI chr 3:49,753,260...49,915,168
Ensembl chr 3:49,753,262...49,915,194

G

collagen type XIV alpha 1 chain

decreases expression

Buspirone results in decreased expression of COL14A1 mRNA

NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214

G

collagen type I alpha 2 chain

decreases expression

Buspirone results in decreased expression of COL1A2 mRNA

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type III alpha 1 chain

decreases expression

Buspirone results in decreased expression of COL3A1 mRNA

NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547

G

COMM domain containing 5

increases expression

Buspirone results in increased expression of COMMD5 mRNA

NCBI chr 7:108,621,766...108,623,616
Ensembl chr 7:108,598,673...108,624,764

G

COPI coat complex subunit gamma 1

decreases expression

Buspirone results in decreased expression of COPG1 mRNA

NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616

G

coronin 1C

decreases expression

Buspirone results in decreased expression of CORO1C mRNA

NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179

G

cytochrome c oxidase assembly factor COX14

increases expression

Buspirone results in increased expression of COX14 mRNA

NCBI chr 7:130,852,226...130,854,316

G

cytochrome c oxidase subunit 7A2 like

increases expression

Buspirone results in increased expression of COX7A2L mRNA

NCBI chr 6:11,184,064...11,198,287
Ensembl chr 6:11,184,285...11,198,273

G

carnitine palmitoyltransferase 1A

increases expression

Buspirone results in increased expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 2

increases expression

Buspirone results in increased expression of CPT2 mRNA

NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095

G

cAMP responsive element modulator

decreases expression

Buspirone results in decreased expression of CREM mRNA

NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989

G

cryptochrome circadian regulator 1

decreases expression

Buspirone results in decreased expression of CRY1 mRNA

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

chromosome segregation 1 like

decreases expression

Buspirone results in decreased expression of CSE1L mRNA

NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865

G

colony stimulating factor 1 receptor

decreases expression

Buspirone results in decreased expression of CSF1R mRNA

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

casein kinase 2 alpha 2

increases expression

Buspirone results in increased expression of CSNK2A2 mRNA

NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080

G

cysteine and glycine-rich protein 1

decreases expression

Buspirone results in decreased expression of CSRP1 mRNA

NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384

G

cathepsin D

increases expression

Buspirone results in increased expression of CTSD mRNA

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

cathepsin L

increases expression

Buspirone results in increased expression of CTSL mRNA

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cathepsin S

decreases expression

Buspirone results in decreased expression of CTSS mRNA

NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483

G

cathepsin Z

decreases expression

Buspirone results in decreased expression of CTSZ mRNA

NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645

G

C-X-C motif chemokine ligand 11

increases expression

Buspirone results in increased expression of CXCL11 mRNA

NCBI chr14:15,689,432...15,692,207
Ensembl chr14:15,689,424...15,692,271

G

cytochrome b-245 beta chain

decreases expression

Buspirone results in decreased expression of CYBB mRNA

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytochrome P450, family 27, subfamily a, polypeptide 1

increases expression

Buspirone results in increased expression of CYP27A1 mRNA

NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551

G

cytochrome P450, family 2, subfamily c, polypeptide 22

decreases expression

Buspirone results in decreased expression of CYP2C22 mRNA

NCBI chr 1:238,991,698...239,031,323
Ensembl chr 1:238,991,610...239,021,738

G

cytochrome P450, family 2, subfamily d, polypeptide 4

increases oxidation
increases expression

CYP2D6 protein results in increased oxidation of Buspirone
Buspirone results in increased expression of CYP2D4 mRNA

PMID:15640381 PMID:24136188

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily j, polypeptide 3

increases expression

Buspirone results in increased expression of CYP2J3 mRNA

NCBI chr 5:111,219,921...111,244,987
Ensembl chr 5:111,178,703...111,244,794

G

cytochrome P450, family 3, subfamily a, polypeptide 2

increases oxidation
increases metabolic processing
multiple interactions

CYP3A4 protein results in increased oxidation of Buspirone
CYP3A4 protein results in increased metabolism of Buspirone
Resveratrol inhibits the reaction [CYP3A4 protein results in increased metabolism of Buspirone]

PMID:15640381 PMID:20716633

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 3, subfamily a, polypeptide 9

increases oxidation
increases expression

CYP3A5 protein results in increased oxidation of Buspirone
Buspirone results in increased expression of CYP3A9 mRNA

PMID:15640381 PMID:24136188

NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422

G

cytochrome P450, family 4, subfamily a, polypeptide 1

increases expression

Buspirone results in increased expression of CYP4A1 mRNA

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

cytochrome P450, family 4, subfamily b, polypeptide 1

increases expression

Buspirone results in increased expression of CYP4B1 mRNA

NCBI chr 5:129,139,019...129,176,860
Ensembl chr 5:129,139,038...129,156,348

G

cytochrome P450, family 4, subfamily f, polypeptide 1

decreases expression

Buspirone results in decreased expression of CYP4F1 mRNA

NCBI chr 7:12,010,850...12,022,497
Ensembl chr 7:12,010,852...12,022,046

G

cytochrome P450, family 4, subfamily f, polypeptide 4

increases expression

Buspirone results in increased expression of CYP4F4 mRNA

NCBI chr 7:11,717,208...11,733,507
Ensembl chr 7:11,717,208...11,733,506

G

cytochrome P450 family 8 subfamily B member 1

increases expression

Buspirone results in increased expression of CYP8B1 mRNA

NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166

G

dishevelled associated activator of morphogenesis 1

decreases expression

Buspirone results in decreased expression of DAAM1 mRNA

NCBI chr 6:90,389,544...90,550,114
Ensembl chr 6:90,389,688...90,550,114

G

DAB adaptor protein 2

decreases expression

Buspirone results in decreased expression of DAB2 mRNA

NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476

G

death associated protein kinase 1

decreases expression

Buspirone results in decreased expression of DAPK1 mRNA

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

G

diazepam binding inhibitor

decreases expression

Buspirone results in decreased expression of DBI mRNA

NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693

G

dopa decarboxylase

decreases expression

Buspirone results in decreased expression of DDC mRNA

NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208

G

DDHD domain containing 1

decreases expression

Buspirone results in decreased expression of DDHD1 mRNA

NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952

G

DEAD-box helicase 1

decreases expression

Buspirone results in decreased expression of DDX1 mRNA

NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365

G

2,4-dienoyl-CoA reductase 1

increases expression

Buspirone results in increased expression of DECR1 mRNA

NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018

G

DEK proto-oncogene

decreases expression

Buspirone results in decreased expression of DEK mRNA

NCBI chr17:17,580,804...17,602,825
Ensembl chr17:17,580,843...17,602,808

G

DEP domain containing MTOR-interacting protein

increases expression

Buspirone results in increased expression of DEPTOR mRNA

NCBI chr 7:86,514,859...86,668,817
Ensembl chr 7:86,514,988...86,667,773

G

dehydrogenase/reductase 7

increases expression

Buspirone results in increased expression of DHRS7 mRNA

NCBI chr 6:91,332,259...91,347,856
Ensembl chr 6:91,251,323...91,347,892

G

dihydrolipoamide dehydrogenase

decreases expression

Buspirone results in decreased expression of DLD mRNA

NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795

G

DnaJ heat shock protein family (Hsp40) member B1

increases expression

Buspirone results in increased expression of DNAJB1 mRNA

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member C9

decreases expression

Buspirone results in decreased expression of DNAJC9 mRNA

NCBI chr15:3,923,842...3,928,118
Ensembl chr15:3,923,268...3,928,118

G

dolichyl-phosphate mannosyltransferase subunit 1, catalytic

increases expression

Buspirone results in increased expression of DPM1 mRNA

NCBI chr 3:156,919,979...156,939,522
Ensembl chr 3:156,919,979...156,939,536

G

dolichyl-phosphate mannosyltransferase subunit 3, regulatory

increases expression

Buspirone results in increased expression of DPM3 mRNA

NCBI chr 2:174,676,532...174,677,047
Ensembl chr 2:174,676,363...174,677,668
Ensembl chr15:174,676,363...174,677,668

G

dihydropyrimidinase-like 2

decreases expression

Buspirone results in decreased expression of DPYSL2 mRNA

NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829

G

deoxythymidylate kinase

decreases expression

Buspirone results in decreased expression of DTYMK mRNA

NCBI chr 9:94,315,552...94,324,386
Ensembl chr 9:94,315,552...94,324,870

G

deoxyuridine triphosphatase

decreases expression

Buspirone results in decreased expression of DUT mRNA

NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771

G

dynein light chain LC8-type 1

decreases expression

Buspirone results in decreased expression of DYNLL1 mRNA

NCBI chr12:41,312,365...41,316,157
Ensembl chr12:41,312,367...41,314,741

G

dynein light chain Tctex-type 3

decreases expression

Buspirone results in decreased expression of DYNLT3 mRNA

NCBI chr X:13,327,933...13,337,139
Ensembl chr X:13,327,892...13,337,139

G

enoyl-CoA hydratase 1

increases expression

Buspirone results in increased expression of ECH1 mRNA

NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795

G

ethylmalonyl-CoA decarboxylase 1

decreases expression

Buspirone results in decreased expression of ECHDC1 mRNA

NCBI chr 1:28,476,354...28,507,173
Ensembl chr 1:28,476,200...28,507,319

G

enoyl CoA hydratase domain containing 3

increases expression

Buspirone results in increased expression of ECHDC3 mRNA

NCBI chr17:72,070,697...72,093,519
Ensembl chr17:72,070,668...72,093,516

G

enoyl-CoA delta isomerase 1

increases expression

Buspirone results in increased expression of ECI1 mRNA

NCBI chr10:13,456,715...13,470,061
Ensembl chr10:13,456,563...13,470,061

G

ER degradation enhancing alpha-mannosidase like protein 1

increases expression

Buspirone results in increased expression of EDEM1 mRNA

NCBI chr 4:141,797,631...141,829,717
Ensembl chr 4:141,797,701...141,829,717

G

elongation factor Tu GTP binding domain containing 2

decreases expression

Buspirone results in decreased expression of EFTUD2 mRNA

NCBI chr10:87,804,893...87,852,181
Ensembl chr10:87,804,892...87,846,079

G

EH domain binding protein 1

decreases expression

Buspirone results in decreased expression of EHBP1 mRNA

NCBI chr14:96,093,327...96,380,502
Ensembl chr14:96,093,327...96,345,332

G

EI24, autophagy associated transmembrane protein

increases expression

Buspirone results in increased expression of EI24 mRNA

NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571

G

eukaryotic translation initiation factor 3, subunit C

decreases expression

Buspirone results in decreased expression of EIF3C mRNA

NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493

G

eukaryotic translation initiation factor 3, subunit L

decreases expression

Buspirone results in decreased expression of EIF3L mRNA

NCBI chr 7:110,652,565...110,663,614
Ensembl chr 7:110,627,107...110,663,614

G

eukaryotic translation initiation factor 4A2

increases expression

Buspirone results in increased expression of EIF4A2 mRNA

NCBI chr11:77,764,126...77,770,810
Ensembl chr11:77,764,124...77,770,781

G

eukaryotic translation initiation factor 4B

increases expression

Buspirone results in increased expression of EIF4B mRNA

NCBI chr 7:133,206,637...133,228,436

G

ELOVL fatty acid elongase 5

decreases expression

Buspirone results in decreased expression of ELOVL5 mRNA

NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284

G

ELOVL fatty acid elongase 6

decreases expression

Buspirone results in decreased expression of ELOVL6 mRNA

NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186

G

glutamyl aminopeptidase

decreases expression

Buspirone results in decreased expression of ENPEP mRNA

NCBI chr 2:217,781,985...217,851,947
Ensembl chr 2:217,782,005...217,851,947

G

epoxide hydrolase 1

decreases expression

Buspirone results in decreased expression of EPHX1 mRNA

NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235

G

ergosterol biosynthesis 28 homolog

increases expression

Buspirone results in increased expression of ERG28 mRNA

NCBI chr 6:105,474,112...105,483,078
Ensembl chr 6:105,474,113...105,483,078

G

endoplasmic reticulum-golgi intermediate compartment 1

decreases expression

Buspirone results in decreased expression of ERGIC1 mRNA

NCBI chr10:16,531,192...16,626,974
Ensembl chr10:16,531,194...16,626,957

G

endoplasmic reticulum protein 29

decreases expression

Buspirone results in decreased expression of ERP29 mRNA

NCBI chr12:35,089,698...35,095,952
Ensembl chr12:35,089,707...35,096,376

G

ethanolamine kinase 2

increases expression

Buspirone results in increased expression of ETNK2 mRNA

NCBI chr13:44,811,012...44,829,052
Ensembl chr13:44,811,015...44,829,037

G

EWS RNA-binding protein 1

decreases expression

Buspirone results in decreased expression of EWSR1 mRNA

NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544

G

exosome component 5

increases expression

Buspirone results in increased expression of EXOSC5 mRNA

NCBI chr 1:81,168,128...81,177,266
Ensembl chr 1:81,166,023...81,177,265

G

fatty acid binding protein 5

decreases expression

Buspirone results in decreased expression of FABP5 mRNA

NCBI chr 2:91,765,056...91,768,716
Ensembl chr 2:91,765,056...91,853,773

G

fatty acid desaturase 1

decreases expression

Buspirone results in decreased expression of FADS1 mRNA

NCBI chr 1:206,827,724...206,842,734
Ensembl chr 1:206,827,765...206,842,734

G

fatty acid desaturase 2

decreases expression

Buspirone results in decreased expression of FADS2 mRNA

NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789

G

FAM111 trypsin like peptidase A

decreases expression

Buspirone results in decreased expression of FAM111A mRNA

NCBI chr 1:209,640,865...209,656,551
Ensembl chr 1:209,640,953...209,656,547

G

family with sequence similarity 98, member A

decreases expression

Buspirone results in decreased expression of FAM98A mRNA

NCBI chr 6:19,874,082...19,888,744
Ensembl chr 6:19,874,071...19,888,742

G

fatty acid synthase

decreases expression

Buspirone results in decreased expression of FASN mRNA

NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261

G

FAT atypical cadherin 1

decreases expression

Buspirone results in decreased expression of FAT1 mRNA

NCBI chr16:47,177,253...47,296,261
Ensembl chr16:47,177,248...47,296,107

G

F-box protein 31

increases expression

Buspirone results in increased expression of FBXO31 mRNA

NCBI chr19:49,624,813...49,656,052
Ensembl chr19:49,627,686...49,656,010

G

F-box and WD repeat domain containing 2

increases expression

Buspirone results in increased expression of FBXW2 mRNA

NCBI chr 3:18,088,859...18,114,387
Ensembl chr 3:18,088,865...18,114,381

G

Fc gamma receptor 2A

decreases expression

Buspirone results in decreased expression of FCGR2A mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

fasciculation and elongation protein zeta 2

decreases expression

Buspirone results in decreased expression of FEZ2 mRNA

NCBI chr 6:16,654,572...16,694,628
Ensembl chr 6:16,654,614...16,694,626

G

fibrinogen alpha chain

decreases expression

Buspirone results in decreased expression of FGA mRNA

NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528

G

fibroblast growth factor receptor 2

decreases expression

Buspirone results in decreased expression of FGFR2 mRNA

NCBI chr 1:184,745,418...184,850,655
Ensembl chr 1:184,745,420...184,850,626

G

folliculin

increases expression

Buspirone results in increased expression of FLCN mRNA

NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769

G

flavin containing dimethylaniline monoxygenase 3

increases expression

Buspirone results in increased expression of FMO3 mRNA

NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028

G

flavin containing dimethylaniline monoxygenase 5

increases expression

Buspirone results in increased expression of FMO5 mRNA

NCBI chr 2:185,197,184...185,249,699
Ensembl chr 2:185,222,204...185,249,693

G

forkhead box A3

increases expression

Buspirone results in increased expression of FOXA3 mRNA

NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155

G

forkhead box O1

increases expression

Buspirone results in increased expression of FOXO1 mRNA

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

follistatin-like 1

decreases expression

Buspirone results in decreased expression of FSTL1 mRNA

NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677

G

formimidoyltransferase cyclodeaminase

increases expression

Buspirone results in increased expression of FTCD mRNA

NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735

G

Fus RNA binding protein

decreases expression

Buspirone results in decreased expression of FUS mRNA

NCBI chr 1:182,576,479...182,590,417
Ensembl chr 1:182,576,545...182,590,414

G

FXYD domain-containing ion transport regulator 1

increases expression

Buspirone results in increased expression of FXYD1 mRNA

NCBI chr 1:86,287,163...86,291,478
Ensembl chr 1:86,287,165...86,291,278

G

G0/G1switch 2

increases expression

Buspirone results in increased expression of G0S2 mRNA

NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451

G

glucose-6-phosphate dehydrogenase

decreases expression

Buspirone results in decreased expression of G6PD mRNA

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

growth arrest and DNA-damage-inducible, gamma

decreases expression

Buspirone results in decreased expression of GADD45G mRNA

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

polypeptide N-acetylgalactosaminyltransferase 1

decreases expression

Buspirone results in decreased expression of GALNT1 mRNA

NCBI chr18:15,489,015...15,568,849
Ensembl chr18:15,489,020...15,568,245

G

glycyl-tRNA synthetase 1

decreases expression

Buspirone results in decreased expression of GARS1 mRNA

NCBI chr 4:84,171,596...84,212,609
Ensembl chr 4:84,171,596...84,212,609

G

growth arrest specific 5

increases expression

Buspirone results in increased expression of GAS5 mRNA

NCBI chr13:73,303,611...73,306,932

G

1,4-alpha-glucan branching enzyme 1

decreases expression

Buspirone results in decreased expression of GBE1 mRNA

NCBI chr11:8,734,806...9,000,226
Ensembl chr11:8,734,820...9,000,210

G

glutaryl-CoA dehydrogenase

increases expression

Buspirone results in increased expression of GCDH mRNA

NCBI chr19:23,263,215...23,269,689
Ensembl chr19:23,263,264...23,269,681

G

GTP cyclohydrolase I feedback regulator

increases expression

Buspirone results in increased expression of GCHFR mRNA

NCBI chr 3:106,158,046...106,162,080
Ensembl chr 3:106,159,394...106,162,080

G

glutamate-cysteine ligase, catalytic subunit

decreases expression

Buspirone results in decreased expression of GCLC mRNA

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glycerophosphodiester phosphodiesterase 1

increases expression

Buspirone results in increased expression of GDE1 mRNA

NCBI chr 1:173,016,984...173,032,396
Ensembl chr 1:172,954,394...173,032,429

G

GDP dissociation inhibitor 2

decreases expression

Buspirone results in decreased expression of GDI2 mRNA

NCBI chr17:66,649,616...66,676,299
Ensembl chr17:66,649,619...66,676,366

G

G elongation factor, mitochondrial 1

decreases expression

Buspirone results in decreased expression of GFM1 mRNA

NCBI chr 2:151,700,573...151,745,477
Ensembl chr 2:151,700,564...151,745,471

G

gamma-glutamyl carboxylase

decreases expression

Buspirone results in decreased expression of GGCX mRNA

NCBI chr 4:104,469,737...104,485,631
Ensembl chr 4:104,469,765...104,487,063

G

growth hormone receptor

decreases expression

Buspirone results in decreased expression of GHR mRNA

NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735

G

glycine decarboxylase

decreases expression

Buspirone results in decreased expression of GLDC mRNA

NCBI chr 1:227,883,249...227,962,119
Ensembl chr 1:227,883,249...227,962,097

G

glutaredoxin

increases expression

Buspirone results in increased expression of GLRX mRNA

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glycine-N-acyltransferase

increases expression

Buspirone results in increased expression of GLYAT mRNA

NCBI chr 1:209,704,213...209,724,949
Ensembl chr 1:209,704,268...209,724,942

G

glucosamine-phosphate N-acetyltransferase 1

decreases expression

Buspirone results in decreased expression of GNPNAT1 mRNA

NCBI chr15:18,596,180...18,608,854
Ensembl chr15:18,596,442...18,608,739

G

glycerol-3-phosphate acyltransferase, mitochondrial

decreases expression

Buspirone results in decreased expression of GPAM mRNA

NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639

G

glycerol-3-phosphate dehydrogenase 1

decreases expression

Buspirone results in decreased expression of GPD1 mRNA

NCBI chr 7:130,842,526...130,851,530
Ensembl chr 7:130,844,138...130,851,529

G

glutamic--pyruvic transaminase

increases expression

Buspirone results in increased expression of GPT mRNA

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

G1 to S phase transition 1

decreases expression

Buspirone results in decreased expression of GSPT1 mRNA

NCBI chr10:4,362,528...4,397,215
Ensembl chr10:4,362,510...4,397,198

G

glutathione S-transferase pi 1

increases expression

Buspirone results in increased expression of GSTP1 mRNA

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

glutathione S-transferase theta 2

increases expression

Buspirone results in increased expression of GSTT2 mRNA

NCBI chr20:12,819,617...12,823,288
Ensembl chr20:12,819,170...12,823,288

G

H1.0 linker histone

decreases expression

Buspirone results in decreased expression of H1F0 mRNA

NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694

G

H2A.Z variant histone 1

decreases expression

Buspirone results in decreased expression of H2AZ1 mRNA

NCBI chr 2:226,355,668...226,357,984
Ensembl chr 2:226,355,708...226,358,485

G

3-hydroxyacyl-CoA dehydratase 2

decreases expression

Buspirone results in decreased expression of HACD2 mRNA

NCBI chr11:65,667,671...65,762,903
Ensembl chr11:65,670,281...65,762,889

G

3-hydroxyacyl-CoA dehydratase 3

decreases expression

Buspirone results in decreased expression of HACD3 mRNA

NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507

G

2-hydroxyacyl-CoA lyase 1

increases expression

Buspirone results in increased expression of HACL1 mRNA

NCBI chr16:6,826,881...6,863,027
Ensembl chr16:6,824,906...6,863,027

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta

increases expression

Buspirone results in increased expression of HADHB mRNA

NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869

G

hydroxyacid oxidase 1

decreases expression

Buspirone results in decreased expression of HAO1 mRNA

NCBI chr 3:121,757,400...121,828,721
Ensembl chr 3:121,771,836...121,828,721

G

histone acetyltransferase 1

decreases expression

Buspirone results in decreased expression of HAT1 mRNA

NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517

G

HAUS augmin-like complex, subunit 4

decreases expression

Buspirone results in decreased expression of HAUS4 mRNA

NCBI chr15:27,994,530...28,006,147
Ensembl chr15:27,994,532...28,005,938

G

hemoglobin alpha, adult chain 1

decreases expression

Buspirone results in decreased expression of HBA-A1 mRNA

NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392

G

hemoglobin alpha, adult chain 2

decreases expression

Buspirone results in decreased expression of HBA1 mRNA

NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392

G

HECT domain E3 ubiquitin protein ligase 1

increases expression

Buspirone results in increased expression of HECTD1 mRNA

NCBI chr 6:69,181,429...69,268,045
Ensembl chr 6:69,181,436...69,268,053

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression

Buspirone results in increased expression of HERPUD1 mRNA

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

hes family bHLH transcription factor 1

increases expression

Buspirone results in increased expression of HES1 mRNA

NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192

G

hes family bHLH transcription factor 6

decreases expression

Buspirone results in decreased expression of HES6 mRNA

NCBI chr 9:92,001,849...92,003,562
Ensembl chr 9:92,001,841...92,003,559

G

hexosaminidase subunit beta

increases expression

Buspirone results in increased expression of HEXB mRNA

NCBI chr 2:28,483,997...28,504,165
Ensembl chr 2:28,484,012...28,504,223

G

hematopoietically expressed homeobox

decreases expression

Buspirone results in decreased expression of HHEX mRNA

NCBI chr 1:235,190,455...235,196,042
Ensembl chr 1:235,190,455...235,196,042

G

3-hydroxyisobutyryl-CoA hydrolase

increases expression

Buspirone results in increased expression of HIBCH mRNA

NCBI chr 9:48,590,097...48,669,896
Ensembl chr 9:48,590,099...48,669,824

G

HIG1 hypoxia inducible domain family, member 2A

increases expression

Buspirone results in increased expression of HIGD2A mRNA

NCBI chr17:10,021,853...10,022,777
Ensembl chr17:10,021,859...10,022,796

G

high mobility group box 2

decreases expression

Buspirone results in decreased expression of HMGB2 mRNA

NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140

G

high mobility group nucleosomal binding domain 2

decreases expression

Buspirone results in decreased expression of HMGN2 mRNA

NCBI chr 5:146,192,126...146,195,580
Ensembl chr 5:146,192,126...146,195,521
Ensembl chr16:146,192,126...146,195,521

G

high mobility group nucleosomal binding domain 3

decreases expression

Buspirone results in decreased expression of HMGN3 mRNA

NCBI chr 8:84,022,493...84,059,329
Ensembl chr 8:84,022,495...84,062,976

G

heme oxygenase 1

multiple interactions
increases expression

Buspirone inhibits the reaction [Methotrexate results in decreased expression of HMOX1 mRNA]
Buspirone results in increased expression of HMOX1 mRNA

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

heterogeneous nuclear ribonucleoprotein A1

decreases expression

Buspirone results in decreased expression of HNRNPA1 mRNA

NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609

G

heterogeneous nuclear ribonucleoprotein A2/B1

decreases expression

Buspirone results in decreased expression of HNRNPA2B1 mRNA

NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249

G

heterogeneous nuclear ribonucleoprotein M

decreases expression

Buspirone results in decreased expression of HNRNPM mRNA

NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762

G

heterogeneous nuclear ribonucleoprotein R

decreases expression

Buspirone results in decreased expression of HNRNPR mRNA

NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867

G

hypoxanthine phosphoribosyltransferase 1

increases expression

Buspirone results in increased expression of HPRT1 mRNA

NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154

G

hydroxysteroid dehydrogenase like 2

increases expression

Buspirone results in increased expression of HSDL2 mRNA

NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839

G

heat shock protein family A (Hsp70) member 13

decreases expression

Buspirone results in decreased expression of HSPA13 mRNA

NCBI chr11:14,375,669...14,389,853
Ensembl chr11:14,373,275...14,389,895

G

heat shock protein family A (Hsp70) member 5

decreases expression

Buspirone results in decreased expression of HSPA5 mRNA

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

HIV-1 Tat specific factor 1

decreases expression

Buspirone results in decreased expression of HTATSF1 mRNA

NCBI chr X:134,935,426...134,949,607
Ensembl chr X:134,935,426...134,949,607

G

5-hydroxytryptamine receptor 1A

multiple interactions

Buspirone binds to and affects the activity of HTR1A protein
Buspirone binds to and results in decreased activity of HTR1A protein

PMID:2207497 PMID:15482641

NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442

G

5-hydroxytryptamine receptor 2A

decreases expression

Buspirone results in decreased expression of HTR2A protein

NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928

G

hyaluronidase 3

decreases expression

Buspirone results in decreased expression of HYAL3 mRNA

NCBI chr 8:108,254,385...108,260,020
Ensembl chr 8:108,250,667...108,260,647

G

hyccin PI4KA lipid kinase complex subunit 2

increases expression

Buspirone results in increased expression of HYCC2 mRNA

NCBI chr 9:60,056,883...60,129,176
Ensembl chr 9:60,056,890...60,093,007

G

isoleucyl-tRNA synthetase 1

decreases expression

Buspirone results in decreased expression of IARS1 mRNA

NCBI chr17:14,940,919...14,987,277
Ensembl chr17:14,940,924...14,987,237

G

intercellular adhesion molecule 1

decreases expression

Buspirone results in decreased expression of ICAM1 mRNA

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

interferon-induced protein with tetratricopeptide repeats 2

decreases expression

Buspirone results in decreased expression of IFIT2 mRNA

NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635

G

interferon induced transmembrane protein 1

decreases expression

Buspirone results in decreased expression of IFITM1 mRNA

NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169

G

insulin-like growth factor 1

decreases expression

Buspirone results in decreased expression of IGF1 mRNA

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor binding protein 7

decreases expression

Buspirone results in decreased expression of IGFBP7 mRNA

NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314

G

IK cytokine

decreases expression

Buspirone results in decreased expression of IK mRNA

NCBI chr18:28,358,004...28,372,809
Ensembl chr18:28,357,977...28,378,832

G

interleukin 1 beta

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of IL1B protein]

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 6

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of IL6 protein]

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 6 receptor

increases expression

Buspirone results in increased expression of IL6R mRNA

NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536

G

IMP U3 small nucleolar ribonucleoprotein 3

increases expression

Buspirone results in increased expression of IMP3 mRNA

NCBI chr 8:57,339,528...57,340,416
Ensembl chr 8:57,339,496...57,340,414

G

inhibin subunit beta A

decreases expression

Buspirone results in decreased expression of INHBA mRNA

NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982

G

inositol hexakisphosphate kinase 1

increases expression

Buspirone results in increased expression of IP6K1 mRNA

NCBI chr 8:108,693,068...108,737,278

G

importin 9

decreases expression

Buspirone results in decreased expression of IPO9 mRNA

NCBI chr13:46,810,460...46,862,694
Ensembl chr13:46,813,171...46,862,673

G

interferon regulatory factor 1

decreases expression

Buspirone results in decreased expression of IRF1 mRNA

NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166

G

interferon regulatory factor 7

decreases expression

Buspirone results in decreased expression of IRF7 mRNA

NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832

G

immunity-related GTPase M

decreases expression

Buspirone results in decreased expression of IRGM mRNA

NCBI chr10:33,233,513...33,241,594
Ensembl chr10:33,233,455...33,241,578

G

integrin subunit alpha 6

decreases expression

Buspirone results in decreased expression of ITGA6 mRNA

NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428

G

integrin subunit beta 2

decreases expression

Buspirone results in decreased expression of ITGB2 mRNA

NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600

G

Janus kinase 1

decreases expression

Buspirone results in decreased expression of JAK1 mRNA

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

G

junctional adhesion molecule 2

decreases expression

Buspirone results in decreased expression of JAM2 mRNA

NCBI chr11:23,830,820...23,880,071
Ensembl chr11:23,831,106...23,880,063

G

Jupiter microtubule associated homolog 2

decreases expression

Buspirone results in decreased expression of JPT2 mRNA

NCBI chr10:13,963,135...13,983,212
Ensembl chr10:13,963,137...13,983,170

G

Jun proto-oncogene, AP-1 transcription factor subunit

decreases expression

Buspirone results in decreased expression of JUN mRNA

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

junction plakoglobin

decreases expression

Buspirone results in decreased expression of JUP mRNA

NCBI chr10:85,300,438...85,327,378
Ensembl chr10:85,300,440...85,327,057

G

potassium channel tetramerization domain containing 5

increases expression

Buspirone results in increased expression of KCTD5 mRNA

NCBI chr10:13,079,216...13,105,197
Ensembl chr10:13,079,214...13,105,209

G

Kelch-like ECH-associated protein 1

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of KEAP1 mRNA]

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

KH RNA binding domain containing, signal transduction associated 1

decreases expression

Buspirone results in decreased expression of KHDRBS1 mRNA

NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180

G

KLF transcription factor 15

increases expression

Buspirone results in increased expression of KLF15 mRNA

NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374

G

KLF transcription factor 9

increases expression

Buspirone results in increased expression of KLF9 mRNA

NCBI chr 1:220,700,108...220,725,110
Ensembl chr 1:220,700,108...220,725,037

G

kelch-like family member 24

increases expression

Buspirone results in increased expression of KLHL24 mRNA

NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636

G

karyopherin subunit alpha 2

decreases expression

Buspirone results in decreased expression of KPNA2 mRNA

NCBI chr10:91,933,951...91,946,115
Ensembl chr10:91,933,951...91,946,150

G

karyopherin subunit beta 1

decreases expression

Buspirone results in decreased expression of KPNB1 mRNA

NCBI chr10:82,145,662...82,174,437
Ensembl chr10:82,145,420...82,174,605

G

keratin 18

decreases expression

Buspirone results in decreased expression of KRT18 mRNA

NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166

G

kynurenine aminotransferase 1

increases expression

Buspirone results in increased expression of KYAT1 mRNA

NCBI chr 3:13,459,598...13,493,308
Ensembl chr 3:13,459,591...13,493,355

G

kynurenine aminotransferase 3

increases expression

Buspirone results in increased expression of KYAT3 mRNA

NCBI chr 2:231,701,881...231,747,462
Ensembl chr 2:231,701,963...231,747,227

G

lactamase, beta

decreases expression

Buspirone results in decreased expression of LACTB mRNA

NCBI chr 8:67,571,504...67,587,592
Ensembl chr 8:67,571,500...67,587,539

G

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

increases expression

Buspirone results in increased expression of LAMTOR2 mRNA

NCBI chr 2:174,008,556...174,011,950
Ensembl chr 2:174,008,548...174,013,013

G

lipopolysaccharide binding protein

increases expression

Buspirone results in increased expression of LBP mRNA

NCBI chr 3:146,953,889...146,981,032
Ensembl chr 3:146,954,015...146,981,586

G

leucine carboxyl methyltransferase 1

decreases expression

Buspirone results in decreased expression of LCMT1 mRNA

NCBI chr 1:177,904,119...177,960,111
Ensembl chr 1:177,904,139...177,960,112

G

lymphocyte cytosolic protein 1

decreases expression

Buspirone results in decreased expression of LCP1 mRNA

NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680

G

leptin receptor overlapping transcript-like 1

increases expression

Buspirone results in increased expression of LEPROTL1 mRNA

NCBI chr16:58,040,934...58,053,602
Ensembl chr16:58,040,960...58,053,593

G

leucine zipper and EF-hand containing transmembrane protein 1

decreases expression

Buspirone results in decreased expression of LETM1 mRNA

NCBI chr14:76,942,647...76,982,220
Ensembl chr14:76,942,729...76,984,904

G

galectin 3

decreases expression

Buspirone results in decreased expression of LGALS3 mRNA

NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025

G

galectin 5

decreases expression

Buspirone results in decreased expression of LGALS5 mRNA

NCBI chr10:63,853,949...63,857,198
Ensembl chr10:63,853,935...63,857,153

G

galectin 9

decreases expression

Buspirone results in decreased expression of LGALS9 mRNA

NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045

G

galectin-like

decreases expression

Buspirone results in decreased expression of LGALSL mRNA

NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980

G

legumain

decreases expression

Buspirone results in decreased expression of LGMN mRNA

NCBI chr 6:121,544,048...121,582,495
Ensembl chr 6:121,544,053...121,582,480

G

lipase C, hepatic type

decreases expression

Buspirone results in decreased expression of LIPC mRNA

NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464

G

lectin, mannose-binding, 1

decreases expression

Buspirone results in decreased expression of LMAN1 mRNA

NCBI chr18:59,508,996...59,530,873
Ensembl chr18:59,508,996...59,530,851

G

lecithin retinol acyltransferase

decreases expression

Buspirone results in decreased expression of LRAT mRNA

NCBI chr 2:168,264,093...168,273,155
Ensembl chr 2:168,266,877...168,273,619

G

LDL receptor related protein 11

increases expression

Buspirone results in increased expression of LRP11 mRNA

NCBI chr 1:2,048,307...2,108,115
Ensembl chr 1:2,079,438...2,108,110

G

leucine rich repeat containing 59

decreases expression

Buspirone results in decreased expression of LRRC59 mRNA

NCBI chr10:79,572,295...79,586,953
Ensembl chr10:79,572,317...79,602,533

G

LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated

decreases expression

Buspirone results in decreased expression of LSM6 mRNA

NCBI chr19:29,098,254...29,112,858
Ensembl chr13:42,114,032...42,116,484
Ensembl chr19:42,114,032...42,116,484

G

leukotriene A4 hydrolase

decreases expression

Buspirone results in decreased expression of LTA4H mRNA

NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600

G

lymphocyte antigen 6 family member E

decreases expression

Buspirone results in decreased expression of LY6E mRNA

NCBI chr 7:106,935,530...106,939,689
Ensembl chr 7:106,935,761...106,939,689

G

lymphatic vessel endothelial hyaluronan receptor 1

decreases expression

Buspirone results in decreased expression of LYVE1 mRNA

NCBI chr 1:164,962,872...164,976,309
Ensembl chr 1:164,962,872...164,976,309

G

lysozyme 2

decreases expression

Buspirone results in decreased expression of LYZ2 mRNA

NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106

G

microtubule-associated protein 1 light chain 3 beta

increases expression

Buspirone results in increased expression of MAP1LC3B mRNA

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

mitogen-activated protein kinase 9

decreases expression

Buspirone results in decreased expression of MAPK9 mRNA

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

microtubule-associated protein, RP/EB family, member 1

decreases expression

Buspirone results in decreased expression of MAPRE1 mRNA

NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983

G

membrane associated ring-CH-type finger 2

increases expression

Buspirone results in increased expression of MARCHF2 mRNA

NCBI chr 7:14,480,605...14,507,821
Ensembl chr 7:14,481,761...14,507,794

G

membrane associated ring-CH-type finger 6

increases expression

Buspirone results in increased expression of MARCHF6 mRNA

NCBI chr 2:82,455,686...82,532,917
Ensembl chr 2:82,455,689...82,532,910

G

MARCKS-like 1

decreases expression

Buspirone results in decreased expression of MARCKSL1 mRNA

NCBI chr 5:141,851,491...141,853,814
Ensembl chr 5:141,850,110...141,853,817

G

meiosis regulator and mRNA stability factor 1

increases expression

Buspirone results in increased expression of MARF1 mRNA

NCBI chr10:888,053...932,760
Ensembl chr10:888,076...932,753

G

methionine adenosyltransferase 1A

increases expression

Buspirone results in increased expression of MAT1A mRNA

NCBI chr16:16,983,084...17,001,284
Ensembl chr16:16,983,022...17,001,274

G

mannose binding lectin 2

decreases expression

Buspirone results in decreased expression of MBL2 mRNA

NCBI chr 1:228,016,439...228,024,736

G

minichromosome maintenance complex component 7

decreases expression

Buspirone results in decreased expression of MCM7 mRNA

NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063

G

malic enzyme 1

decreases expression

Buspirone results in decreased expression of ME1 mRNA

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

methyltransferase 23, arginine

increases expression

Buspirone results in increased expression of METTL23 mRNA

NCBI chr10:102,047,090...102,053,379
Ensembl chr10:102,047,314...102,051,977

G

MFSD2 lysolipid transporter A, lysophospholipid

increases expression

Buspirone results in increased expression of MFSD2A mRNA

NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690

G

monoglyceride lipase

decreases expression

Buspirone results in decreased expression of MGLL mRNA

NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179

G

MID1 interacting protein 1

decreases expression

Buspirone results in decreased expression of MID1IP1 mRNA

NCBI chr X:12,060,993...12,063,318
Ensembl chr X:12,060,883...12,065,774

G

macrophage migration inhibitory factor

decreases expression

Buspirone results in decreased expression of MIF mRNA

NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504

G

mortality factor 4 like 2

decreases expression

Buspirone results in decreased expression of MORF4L2 mRNA

NCBI chr X:100,082,562...100,093,658
Ensembl chr X:100,082,404...100,093,728

G

mitochondrial ribosomal protein L1

decreases expression

Buspirone results in decreased expression of MRPL1 mRNA

NCBI chr14:13,300,522...13,359,654
Ensembl chr14:13,300,522...13,359,721

G

mitochondrial ribosomal protein L15

decreases expression

Buspirone results in decreased expression of MRPL15 mRNA

NCBI chr 5:14,729,961...14,741,276
Ensembl chr 5:14,729,979...14,741,276

G

mitochondrial ribosomal protein L34

increases expression

Buspirone results in increased expression of MRPL34 mRNA

NCBI chr16:18,152,470...18,153,205
Ensembl chr16:18,151,342...18,153,208

G

mitochondrial ribosomal protein S22

decreases expression

Buspirone results in decreased expression of MRPS22 mRNA

NCBI chr 8:99,184,110...99,197,278
Ensembl chr 8:99,184,109...99,197,291

G

metallothionein 1

increases expression

Buspirone results in increased expression of MT1A mRNA

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

G

mitochondrial amidoxime reducing component 2

increases expression

Buspirone results in increased expression of MTARC2 mRNA

NCBI chr13:96,362,810...96,397,284

G

methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1

decreases expression

Buspirone results in decreased expression of MTHFD1 mRNA

NCBI chr 6:94,977,862...95,045,375
Ensembl chr 6:94,977,862...95,045,372

G

MTSS I-BAR domain containing 1

increases expression

Buspirone results in increased expression of MTSS1 mRNA

NCBI chr 7:90,488,751...90,628,007
Ensembl chr 7:90,488,754...90,627,968

G

microsomal triglyceride transfer protein

decreases expression

Buspirone results in decreased expression of MTTP mRNA

NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239

G

murinoglobulin 1

decreases expression

Buspirone results in decreased expression of MUG1 mRNA

NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051

G

MYD88, innate immune signal transduction adaptor

increases expression

Buspirone results in increased expression of MYD88 mRNA

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

G

myosin, heavy chain 9

decreases expression

Buspirone results in decreased expression of MYH9 mRNA

NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457

G

N(alpha)-acetyltransferase 15, NatA auxiliary subunit

decreases expression

Buspirone results in decreased expression of NAA15 mRNA

NCBI chr 2:135,458,018...135,520,756
Ensembl chr 2:135,457,948...135,520,756

G

N-acetylneuraminate synthase

decreases expression

Buspirone results in decreased expression of NANS mRNA

NCBI chr 5:60,780,441...60,797,583
Ensembl chr 5:60,780,392...60,814,950

G

Nedd4 family interacting protein 1

increases expression

Buspirone results in increased expression of NDFIP1 mRNA

NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311

G

NADH:ubiquinone oxidoreductase subunit A6

increases expression

Buspirone results in increased expression of NDUFA6 mRNA

NCBI chr 7:113,866,382...113,870,239
Ensembl chr 7:113,866,382...113,870,239

G

NADH:ubiquinone oxidoreductase subunit A7

increases expression

Buspirone results in increased expression of NDUFA7 mRNA

NCBI chr 7:14,609,283...14,622,064
Ensembl chr 7:14,609,146...14,631,976

G

NADH:ubiquinone oxidoreductase subunit B2

increases expression

Buspirone results in increased expression of NDUFB2 mRNA

NCBI chr 4:68,367,526...68,374,609
Ensembl chr15:46,536,062...46,536,851
Ensembl chr 4:46,536,062...46,536,851

G

nectin cell adhesion molecule 3

decreases expression

Buspirone results in decreased expression of NECTIN3 mRNA

NCBI chr11:54,362,712...54,469,351
Ensembl chr11:54,364,487...54,462,519

G

NFE2 like bZIP transcription factor 2

decreases expression
multiple interactions
increases expression

Buspirone results in decreased expression of NFE2L2 mRNA
Buspirone inhibits the reaction [Methotrexate results in decreased expression of NFE2L2 mRNA]
Buspirone results in increased expression of NFE2L2 mRNA

PMID:24136188 PMID:37341015

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

NHP2 ribonucleoprotein

decreases expression

Buspirone results in decreased expression of NHP2 mRNA

NCBI chr10:35,877,057...35,880,399
Ensembl chr10:35,877,054...35,882,545

G

nidogen 1

decreases expression

Buspirone results in decreased expression of NID1 mRNA

NCBI chr17:86,085,133...86,158,272
Ensembl chr17:86,085,077...86,158,267

G

nitrilase 1

increases expression

Buspirone results in increased expression of NIT1 mRNA

NCBI chr13:83,769,888...83,773,324
Ensembl chr13:83,765,941...83,773,332

G

neurolysin

decreases expression

Buspirone results in decreased expression of NLN mRNA

NCBI chr 2:35,133,634...35,232,927
Ensembl chr 2:35,134,145...35,232,914

G

NLR family, pyrin domain containing 3

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of NLRP3 protein]

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

G

NME/NM23 nucleoside diphosphate kinase 1

decreases expression

Buspirone results in decreased expression of NME1 mRNA

NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408

G

NME/NM23 nucleoside diphosphate kinase 3

increases expression

Buspirone results in increased expression of NME3 mRNA

NCBI chr10:13,917,309...13,918,415
Ensembl chr10:13,917,403...13,918,359

G

NOP53 ribosome biogenesis factor

increases expression

Buspirone results in increased expression of NOP53 mRNA

NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902

G

NOP58 ribonucleoprotein

decreases expression

Buspirone results in decreased expression of NOL5 mRNA

NCBI chr 9:61,120,939...61,144,810
Ensembl chr 9:61,120,929...61,144,810

G

nitric oxide synthase 1

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of NOS1 mRNA]

NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945

G

notch receptor 2

decreases expression

Buspirone results in decreased expression of NOTCH2 mRNA

NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088

G

nuclear receptor subfamily 1, group D, member 2

increases expression

Buspirone results in increased expression of NR1D2 mRNA

NCBI chr15:7,524,257...7,550,553
Ensembl chr15:7,524,257...7,550,553

G

nuclear receptor subfamily 1, group I, member 2

increases expression

Buspirone results in increased expression of NR1I2 mRNA

NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658

G

nuclear receptor binding protein 2

increases expression

Buspirone results in increased expression of NRBP2 mRNA

NCBI chr 7:107,798,642...107,805,225
Ensembl chr 7:107,799,497...107,805,230

G

neuronal regeneration related protein

decreases expression

Buspirone results in decreased expression of NREP mRNA

NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591

G

NAD(P) dependent steroid dehydrogenase-like

decreases expression

Buspirone results in decreased expression of NSDHL mRNA

NCBI chr X:150,775,034...150,807,161
Ensembl chr X:150,775,080...150,807,142

G

5' nucleotidase, ecto

decreases expression

Buspirone results in decreased expression of NT5E mRNA

NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881

G

nucleoside-triphosphatase, cancer-related

increases expression

Buspirone results in increased expression of NTPCR mRNA

NCBI chr19:53,701,496...53,715,260
Ensembl chr19:53,695,976...53,715,202

G

nucleobindin 2

decreases expression

Buspirone results in decreased expression of NUCB2 mRNA

NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353

G

nudix hydrolase 4

increases expression

Buspirone results in increased expression of NUDT4 mRNA

NCBI chr 7:30,188,100...30,204,615
Ensembl chr 7:30,188,100...30,204,615

G

alpha-2u globulin PGCL4

increases expression

Buspirone results in increased expression of OBP3 mRNA

NCBI chr 5:74,842,316...74,845,858
Ensembl chr 5:74,842,316...74,845,757

G

Obg-like ATPase 1

decreases expression

Buspirone results in decreased expression of OLA1 mRNA

NCBI chr 3:57,966,896...58,085,955
Ensembl chr 3:57,966,896...58,084,480

G

5-oxoprolinase (ATP-hydrolysing)

increases expression

Buspirone results in increased expression of OPLAH mRNA

NCBI chr 7:108,011,472...108,051,751
Ensembl chr 7:108,011,475...108,035,297

G

oxysterol binding protein-like 1A

decreases expression

Buspirone results in decreased expression of OSBPL1A mRNA

NCBI chr18:3,904,006...4,094,635
Ensembl chr18:3,904,006...4,094,585

G

phosphatase domain containing, paladin 1

increases expression

Buspirone results in increased expression of PALD1 mRNA

NCBI chr20:29,269,814...29,334,850
Ensembl chr20:29,270,193...29,334,858

G

palmdelphin

decreases expression

Buspirone results in decreased expression of PALMD mRNA

NCBI chr 2:204,889,526...204,941,355
Ensembl chr 2:204,889,533...204,941,519

G

progestin and adipoQ receptor family member 9

decreases expression

Buspirone results in decreased expression of PAQR9 mRNA

NCBI chr 8:96,114,249...96,116,546

G

poly (ADP-ribose) polymerase family, member 14

decreases expression

Buspirone results in decreased expression of PARP14 mRNA

NCBI chr11:64,902,848...64,934,916
Ensembl chr11:64,902,785...64,934,916

G

phenazine biosynthesis-like protein domain containing 1

increases expression

Buspirone results in increased expression of PBLD1 mRNA

NCBI chr20:25,551,274...25,566,543
Ensembl chr20:25,551,275...25,565,614

G

proliferating cell nuclear antigen

decreases expression

Buspirone results in decreased expression of PCNA mRNA

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

phosphatidylcholine transfer protein

decreases expression

Buspirone results in decreased expression of PCTP mRNA

NCBI chr10:74,808,887...74,856,260
Ensembl chr10:74,808,887...74,849,867

G

phosphate cytidylyltransferase 1A, choline

increases expression

Buspirone results in increased expression of PCYT1A mRNA

NCBI chr11:68,313,860...68,357,828
Ensembl chr11:68,313,882...68,357,357

G

programmed cell death 4

decreases expression

Buspirone results in decreased expression of PDCD4 mRNA

NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275

G

phosphodiesterase 4B

decreases expression

Buspirone results in decreased expression of PDE4B mRNA

NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696

G

protein disulfide isomerase family A, member 5

decreases expression

Buspirone results in decreased expression of PDIA5 mRNA

NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084

G

protein disulfide isomerase family A, member 6

decreases expression

Buspirone results in decreased expression of PDIA6 mRNA

NCBI chr 6:40,062,980...40,080,223
Ensembl chr 6:40,062,926...40,080,613

G

PDZ and LIM domain 1

decreases expression

Buspirone results in decreased expression of PDLIM1 mRNA

NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076

G

peroxisomal biogenesis factor 11 alpha

increases expression

Buspirone results in increased expression of PEX11A mRNA

NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172

G

phosphogluconate dehydrogenase

decreases expression

Buspirone results in decreased expression of PGD mRNA

NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778

G

phosphoglycerate kinase 1

decreases expression

Buspirone results in decreased expression of PGK1 mRNA

NCBI chr X:71,271,454...71,287,429
Ensembl chr X:71,271,440...71,287,418

G

PHD finger protein 11

decreases expression

Buspirone results in decreased expression of PHF11 mRNA

NCBI chr15:33,390,290...33,414,647
Ensembl chr15:33,390,292...33,413,009

G

phytanoyl-CoA dioxygenase domain containing 1

increases expression

Buspirone results in increased expression of PHYHD1 mRNA

NCBI chr 3:13,535,670...13,553,797
Ensembl chr 3:13,540,056...13,553,797

G

Pim-3 proto-oncogene, serine/threonine kinase

increases expression

Buspirone results in increased expression of PIM3 mRNA

NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587

G

PTEN induced kinase 1

increases expression

Buspirone results in increased expression of PINK1 mRNA

NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635

G

pyruvate kinase L/R

decreases expression

Buspirone results in decreased expression of PKLR mRNA

NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870

G

phospholipase A2, group XIIA

increases expression

Buspirone results in increased expression of PLA2G12A mRNA

NCBI chr 2:218,436,497...218,452,742
Ensembl chr 2:218,436,513...218,452,740

G

phospholipase C beta 1

decreases expression

Buspirone results in decreased expression of PLCB1 mRNA; Buspirone results in decreased expression of PLCB1 protein

NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869

G

perilipin 2

decreases expression

Buspirone results in decreased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

perilipin 3

decreases expression

Buspirone results in decreased expression of PLIN3 mRNA

NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147

G

phospholipid phosphatase 3

increases expression

Buspirone results in increased expression of PLPP3 mRNA

NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205

G

plexin A2

decreases expression

Buspirone results in decreased expression of PLXNA2 mRNA

NCBI chr13:106,163,103...106,358,979
Ensembl chr13:106,163,103...106,358,979

G

patatin-like phospholipase domain containing 2

increases expression

Buspirone results in increased expression of PNPLA2 mRNA

NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805

G

patatin-like phospholipase domain containing 7

increases expression

Buspirone results in increased expression of PNPLA7 mRNA

NCBI chr 3:7,782,572...7,861,504
Ensembl chr 3:7,782,572...7,861,497

G

patatin-like phospholipase domain containing 8

increases expression

Buspirone results in increased expression of PNPLA8 mRNA

NCBI chr 6:61,329,810...61,391,736
Ensembl chr 6:61,329,810...61,391,734

G

DNA polymerase delta 4, accessory subunit

increases expression

Buspirone results in increased expression of POLD4 mRNA

NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401

G

DNA polymerase gamma 2, accessory subunit

increases expression

Buspirone results in increased expression of POLG2 mRNA

NCBI chr10:91,712,586...91,723,008
Ensembl chr10:91,712,586...91,723,008

G

RNA polymerase II subunit B

decreases expression

Buspirone results in decreased expression of POLR2B mRNA

NCBI chr14:30,797,228...30,834,916
Ensembl chr14:30,797,228...30,834,916

G

polymerase (RNA) II (DNA directed) polypeptide H, pseudogene 1

increases expression

Buspirone results in increased expression of POLR2H-PS1 mRNA

NCBI chr10:104,854,977...104,856,390

G

proopiomelanocortin

increases expression
multiple interactions

Buspirone results in increased expression of POMC protein
Imipramine inhibits the reaction [Buspirone results in increased expression of POMC protein]

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

G

cytochrome p450 oxidoreductase

increases expression

Buspirone results in increased expression of POR mRNA

NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245

G

inorganic pyrophosphatase 1

decreases expression

Buspirone results in decreased expression of PPA1 mRNA

NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215

G

peroxisome proliferator-activated receptor gamma

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in decreased expression of PPARG mRNA]

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

phosphopantothenoylcysteine synthetase

increases expression

Buspirone results in increased expression of PPCS mRNA

NCBI chr 5:133,023,077...133,026,899
Ensembl chr 5:133,023,121...133,026,933

G

protoporphyrinogen oxidase

decreases expression

Buspirone results in decreased expression of PPOX mRNA

NCBI chr13:83,697,661...83,701,998
Ensembl chr13:83,664,891...83,701,805

G

protein phosphatase 1, regulatory (inhibitor) subunit 14A

decreases expression

Buspirone results in decreased expression of PPP1R14A mRNA

NCBI chr 1:84,583,127...84,590,743
Ensembl chr 1:84,586,627...84,590,671

G

protein phosphatase 1, regulatory subunit 21

decreases expression

Buspirone results in decreased expression of PPP1R21 mRNA

NCBI chr 6:5,901,518...5,970,684
Ensembl chr 6:5,901,518...5,970,684

G

protein regulator of cytokinesis 1

decreases expression

Buspirone results in decreased expression of PRC1 mRNA

NCBI chr 1:134,250,086...134,271,765
Ensembl chr 1:134,250,081...134,271,765

G

peroxiredoxin 5

increases expression

Buspirone results in increased expression of PRDX5 mRNA

NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268

G

protein kinase cAMP-activated catalytic subunit alpha

decreases expression

Buspirone results in decreased expression of PRKACA mRNA

NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430

G

prolactin

increases secretion
multiple interactions
increases expression

Buspirone results in increased secretion of PRL protein
Pindolol inhibits the reaction [Buspirone results in increased secretion of PRL protein]
Buspirone results in increased expression of PRL protein

PMID:18194152 PMID:19762159

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

G

proline and serine rich 2

increases expression

Buspirone results in increased expression of PROSER2 mRNA

NCBI chr17:72,151,961...72,187,524
Ensembl chr17:72,151,872...72,185,825

G

proline rich 13

decreases expression

Buspirone results in decreased expression of PRR13 mRNA

NCBI chr 7:133,592,511...133,595,817
Ensembl chr 7:133,592,490...133,601,005

G

serine protease 23

decreases expression

Buspirone results in decreased expression of PRSS23 mRNA

NCBI chr 1:143,402,725...143,422,182
Ensembl chr 1:143,401,396...143,422,091

G

presenilin enhancer gamma secretase subunit

increases expression

Buspirone results in increased expression of PSENEN mRNA

NCBI chr 1:85,814,905...85,816,654
Ensembl chr 1:85,814,905...85,816,192

G

proteasome 20S subunit beta 10

decreases expression

Buspirone results in decreased expression of PSMB10 mRNA

NCBI chr19:33,830,958...33,833,442
Ensembl chr19:33,827,229...33,833,626

G

proteasome 20S subunit beta 3

increases expression

Buspirone results in increased expression of PSMB3 mRNA

NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521

G

proteasome 20S subunit beta 4

increases expression

Buspirone results in increased expression of PSMB4 mRNA

NCBI chr 2:182,442,757...182,445,532
Ensembl chr 2:182,442,756...182,445,746

G

proteasome 20S subunit beta 8

decreases expression

Buspirone results in decreased expression of PSMB8 mRNA

NCBI chr20:4,652,159...4,655,122
Ensembl chr20:4,652,159...4,655,283

G

proteasome 20S subunit beta 9

decreases expression

Buspirone results in decreased expression of PSMB9 mRNA

NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512

G

prostaglandin reductase 3

increases expression

Buspirone results in increased expression of PTGR3 mRNA

NCBI chr18:77,454,435...77,463,785
Ensembl chr18:77,454,435...77,463,785

G

prothymosin alpha

decreases expression

Buspirone results in decreased expression of PTMA mRNA

NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333

G

protein tyrosine phosphatase, receptor type, F

decreases expression

Buspirone results in decreased expression of PTPRF mRNA

NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023

G

PTTG1 regulator of sister chromatid separation, securin

decreases expression

Buspirone results in decreased expression of PTTG1 mRNA

NCBI chr10:27,893,466...27,904,965
Ensembl chr10:27,893,689...27,904,837

G

PYD and CARD domain containing

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of PYCARD protein]

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

G

glycogen phosphorylase L

decreases expression

Buspirone results in decreased expression of PYGL mRNA

NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310

G

R3H domain containing 2

decreases expression

Buspirone results in decreased expression of R3HDM2 mRNA

NCBI chr 7:63,212,519...63,340,574
Ensembl chr 7:63,232,346...63,340,540

G

RAB17, member RAS oncogene family

increases expression

Buspirone results in increased expression of RAB17 mRNA

NCBI chr 9:91,552,924...91,566,759
Ensembl chr 9:91,553,464...91,566,451

G

RAB29, member RAS oncogene family

increases expression

Buspirone results in increased expression of RAB29 mRNA

NCBI chr13:43,307,757...43,313,420
Ensembl chr13:43,307,775...43,313,417

G

RAB30, member RAS oncogene family

increases expression

Buspirone results in increased expression of RAB30 mRNA

NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181

G

RAB34, member RAS oncogene family

increases expression

Buspirone results in increased expression of RAB34 mRNA

NCBI chr10:63,083,319...63,087,538
Ensembl chr10:63,083,338...63,087,538

G

RAB38, member RAS oncogene family

decreases expression

Buspirone results in decreased expression of RAB38 mRNA

NCBI chr 1:142,182,566...142,262,923
Ensembl chr 1:142,182,556...142,262,924

G

RAB5 interacting factor

increases expression

Buspirone results in increased expression of RAB5IF mRNA

NCBI chr 3:145,357,990...145,368,012
Ensembl chr 3:145,357,861...145,368,012

G

RAB7A, member RAS oncogene family

decreases expression

Buspirone results in decreased expression of RAB7A mRNA

NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889

G

Rab acceptor 1

increases expression

Buspirone results in increased expression of RABAC1 mRNA

NCBI chr 1:80,564,029...80,567,164
Ensembl chr 1:80,564,033...80,567,163

G

RAN, member RAS oncogene family

decreases expression

Buspirone results in decreased expression of RAN mRNA

NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276

G

RAN GTPase activating protein 1

decreases expression

Buspirone results in decreased expression of RANGAP1 mRNA

NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438

G

Rap guanine nucleotide exchange factor 4

increases expression

Buspirone results in increased expression of RAPGEF4 mRNA

NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316

G

retinoic acid receptor, beta

decreases expression

Buspirone results in decreased expression of RARB mRNA

NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288

G

RB transcriptional corepressor 1

decreases expression

Buspirone results in decreased expression of RB1 mRNA

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

ribosome binding factor A

decreases expression

Buspirone results in decreased expression of RBFA mRNA

NCBI chr18:73,639,264...73,648,914
Ensembl chr18:73,639,260...73,648,915

G

regulator of calcineurin 1

decreases expression

Buspirone results in decreased expression of RCAN1 mRNA

NCBI chr11:31,622,208...31,702,150
Ensembl chr11:31,622,210...31,702,045

G

RNA terminal phosphate cyclase-like 1

increases expression

Buspirone results in increased expression of RCL1 mRNA

NCBI chr 1:226,824,561...226,869,046
Ensembl chr 1:226,824,534...226,902,315

G

retinol dehydrogenase 11

decreases expression

Buspirone results in decreased expression of RDH11 mRNA

NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252

G

RELA proto-oncogene, NF-kB subunit

multiple interactions

Buspirone inhibits the reaction [Methotrexate results in increased expression of RELA mRNA]

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

reticulophagy regulator 1

increases expression

Buspirone results in increased expression of RETREG1 mRNA

NCBI chr 2:76,335,609...76,474,817
Ensembl chr 2:76,335,609...76,493,898

G

required for excision 1-B domain containing

increases expression

Buspirone results in increased expression of REX1BD mRNA

NCBI chr16:18,922,050...18,924,521
Ensembl chr16:18,922,037...18,924,526

G

ras homolog family member B

decreases expression

Buspirone results in decreased expression of RHOB mRNA

NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108

G

RNA sensor RIG-1

decreases expression

Buspirone results in decreased expression of RIGI mRNA

NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819

G

Rho family GTPase 2

increases expression

Buspirone results in increased expression of RND2 mRNA

NCBI chr10:86,399,151...86,402,750
Ensembl chr10:86,399,148...86,402,742

G

ring finger protein 125

decreases expression

Buspirone results in decreased expression of RNF125 mRNA

NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983

G

ring finger protein 139

increases expression

Buspirone results in increased expression of RNF139 mRNA

NCBI chr 7:90,439,726...90,450,911
Ensembl chr 7:90,436,621...90,488,009

G

ring finger protein 149

increases expression

Buspirone results in increased expression of RNF149 mRNA

NCBI chr 9:41,826,825...41,854,381
Ensembl chr 9:41,830,233...41,854,279

G

ring finger protein 26

decreases expression

Buspirone results in decreased expression of RNF26 mRNA

NCBI chr 8:44,454,551...44,456,745
Ensembl chr 8:44,454,292...44,457,331

G

RAR-related orphan receptor C

decreases expression

Buspirone results in decreased expression of RORC mRNA

NCBI chr 2:182,009,707...182,034,910
Ensembl chr 2:182,009,286...182,034,907

G

replication protein A1

decreases expression

Buspirone results in decreased expression of RPA1 mRNA

NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949

G

replication protein A3

decreases expression

Buspirone results in decreased expression of RPA3 mRNA

NCBI chr 4:36,304,649...36,307,755
Ensembl chr 4:36,304,651...36,307,709

G

ribulose-5-phosphate-3-epimerase

decreases expression

Buspirone results in decreased expression of RPE mRNA

NCBI chr 9:68,191,027...68,211,295
Ensembl chr 9:68,191,292...68,211,591

G

ribosomal protein L7-like 1

decreases expression

Buspirone results in decreased expression of RPL7L1 mRNA

NCBI chr 9:14,198,101...14,206,119
Ensembl chr 9:14,198,092...14,206,110

G

ribophorin I

decreases expression

Buspirone results in decreased expression of RPN1 mRNA

NCBI chr 4:120,543,667...120,565,069
Ensembl chr 4:120,543,667...120,565,069

G

ribonucleotide reductase regulatory subunit M2

decreases expression

Buspirone results in decreased expression of RRM2 mRNA

NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773

G

RT1 class II, locus Ba

decreases expression

Buspirone results in decreased expression of RT1-BA mRNA

NCBI chr20:4,575,134...4,579,727
Ensembl chr20:4,575,134...4,579,744

G

RT1 class II, locus Da

decreases expression

Buspirone results in decreased expression of RT1-DA mRNA

NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455

G

RT1 class II, locus DMb

decreases expression

Buspirone results in decreased expression of HLA-DMB mRNA

NCBI chr20:4,693,102...4,700,340
Ensembl chr20:4,693,103...4,700,340

G

RT1 class Ib, locus S3

decreases expression

Buspirone results in decreased expression of RT1-S3 mRNA

NCBI chr20:2,670,654...2,675,411
Ensembl chr20:2,670,709...2,675,411

G

S100 calcium binding protein B

decreases response to substance

S100B results in decreased susceptibility to Buspirone

NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743

G

SUMO1 activating enzyme subunit 1

decreases expression

Buspirone results in decreased expression of SAE1 mRNA

NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986

G

spalt-like transcription factor 1

increases expression

Buspirone results in increased expression of SALL1 mRNA

NCBI chr19:18,005,782...18,022,705
Ensembl chr19:18,007,503...18,022,705

G

secretion associated, Ras related GTPase 1B

increases expression

Buspirone results in increased expression of SAR1B mRNA

NCBI chr10:36,024,415...36,054,069
Ensembl chr10:36,024,382...36,054,066

G

SAP domain containing ribonucleoprotein

decreases expression

Buspirone results in decreased expression of SARNP mRNA

NCBI chr 7:1,251,096...1,305,335
Ensembl chr 7:1,251,098...1,305,332

G

spermidine/spermine N1-acetyltransferase family member 2

increases expression

Buspirone results in increased expression of SAT2 mRNA

NCBI chr10:54,340,756...54,343,507
Ensembl chr10:54,340,372...54,343,224

G

scavenger receptor class B, member 1

decreases expression

Buspirone results in decreased expression of SCARB1 mRNA

NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647

G

stearoyl-CoA desaturase

decreases expression

Buspirone results in decreased expression of SCD1 mRNA

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

sec1 family domain containing 1

decreases expression

Buspirone results in decreased expression of SCFD1 mRNA

NCBI chr 6:68,795,810...68,874,076
Ensembl chr 6:68,795,878...68,874,078

G

selenocysteine lyase

decreases expression

Buspirone results in decreased expression of SCLY mRNA

NCBI chr 9:91,890,269...91,910,947
Ensembl chr 9:91,890,306...91,910,941

G

syndecan 4

increases expression

Buspirone results in increased expression of SDC4 mRNA

NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580

G

stromal cell derived factor 2

increases expression

Buspirone results in increased expression of SDF2 mRNA

NCBI chr10:63,140,563...63,151,038
Ensembl chr10:63,140,563...63,201,109

G

serine dehydratase

increases expression

Buspirone results in increased expression of SDS mRNA

NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203

G

SEC13 homolog, nuclear pore and COPII coat complex component

decreases expression

Buspirone results in decreased expression of SEC13 mRNA

NCBI chr 4:146,877,739...146,891,130
Ensembl chr 4:146,875,524...146,891,173

G

SEC22 homolog B, vesicle trafficking protein

decreases expression

Buspirone results in decreased expression of SEC22B mRNA

NCBI chr 2:185,500,029...185,520,811
Ensembl chr 2:185,500,004...185,522,026

G

Sec23 homolog B, COPII coat complex component

decreases expression

Buspirone results in decreased expression of SEC23B mRNA

NCBI chr 3:131,939,011...131,981,489
Ensembl chr 3:131,939,337...131,981,489

G

SEC61 translocon subunit alpha 1

decreases expression

Buspirone results in decreased expression of SEC61A1 mRNA

NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925

G

SEC63 homolog, protein translocation regulator

decreases expression

Buspirone results in decreased expression of SEC63 mRNA

NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055

G

SECIS binding protein 2-like

decreases expression

Buspirone results in decreased expression of SECISBP2L mRNA

NCBI chr 3:112,989,613...113,036,060
Ensembl chr 3:112,991,908...113,035,884

G

septin 10

decreases expression

Buspirone results in decreased expression of SEPTIN10 mRNA

NCBI chr20:27,101,764...27,194,997
Ensembl chr20:27,101,752...27,194,780

G

septin 7

decreases expression

Buspirone results in decreased expression of SEPTIN7 mRNA

NCBI chr 8:23,719,448...23,783,247
Ensembl chr 8:23,716,030...23,783,243

G

septin 9

decreases expression

Buspirone results in decreased expression of SEPTIN9 mRNA

NCBI chr10:102,409,798...102,579,056
Ensembl chr10:102,409,711...102,579,055

G

serpin family A member 11

increases expression

Buspirone results in increased expression of SERPINA11 mRNA

NCBI chr 6:122,903,246...122,912,695
Ensembl chr 6:122,903,250...122,912,670

G

serpin family A member 6

decreases expression

Buspirone results in decreased expression of SERPINA6 mRNA

NCBI chr 6:122,780,040...122,790,274
Ensembl chr 6:122,780,043...122,790,349

G

serpin family B member 9

decreases expression

Buspirone results in decreased expression of SERPINB9 mRNA

NCBI chr17:31,420,118...31,443,237
Ensembl chr17:31,420,125...31,443,230

G

splicing factor 3a, subunit 3

decreases expression

Buspirone results in decreased expression of SF3A3 mRNA

NCBI chr 5:136,967,713...136,987,345
Ensembl chr 5:136,967,691...136,987,361

G

splicing factor proline and glutamine rich

decreases expression

Buspirone results in decreased expression of SFPQ mRNA

NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472

G

SFT2 domain containing 2

increases expression

Buspirone results in increased expression of SFT2D2 mRNA

NCBI chr13:77,484,778...77,504,123
Ensembl chr13:77,484,636...77,504,112

G

serum/glucocorticoid regulated kinase 1

decreases expression

Buspirone results in decreased expression of SGK1 mRNA

NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283

G

sphingosine-1-phosphate phosphatase 1

increases expression

Buspirone results in increased expression of SGPP1 mRNA

NCBI chr 6:94,425,339...94,446,534
Ensembl chr 6:94,425,339...94,446,534

G

SH3 domain binding glutamate-rich protein like 3

decreases expression

Buspirone results in decreased expression of SH3BGRL3 mRNA

NCBI chr 5:146,354,152...146,355,525
Ensembl chr 5:146,354,152...146,355,331

G

SH3-domain binding protein 5

increases expression

Buspirone results in increased expression of SH3BP5 mRNA

NCBI chr16:6,583,462...6,678,344
Ensembl chr16:6,583,465...6,698,975

G

serine hydroxymethyltransferase 2

decreases expression

Buspirone results in decreased expression of SHMT2 mRNA

NCBI chr 7:63,358,961...63,364,293
Ensembl chr 7:63,358,961...63,364,236

G

SID1 transmembrane family, member 2

increases expression

Buspirone results in increased expression of SIDT2 mRNA

NCBI chr 8:46,232,379...46,248,913
Ensembl chr 8:46,232,383...46,248,700

G

SIN3 transcription regulator family member B

increases expression

Buspirone results in increased expression of SIN3B mRNA

NCBI chr16:17,123,277...17,159,978
Ensembl chr16:17,123,434...17,159,978

G

sirtuin 5

decreases expression

Buspirone results in decreased expression of SIRT5 mRNA

NCBI chr17:21,310,028...21,337,137
Ensembl chr17:21,310,028...21,337,101

G

solute carrier family 17 member 3

decreases expression

Buspirone results in decreased expression of SLC17A3 mRNA

NCBI chr17:41,270,804...41,300,132
Ensembl chr17:41,270,812...41,295,256

G

solute carrier family 22 member 2

multiple interactions

Buspirone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium]

NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268

G

solute carrier family 25 member 17

increases expression

Buspirone results in increased expression of SLC25A17 mRNA

NCBI chr 7:112,844,375...112,887,014
Ensembl chr 7:112,844,375...112,925,945

G

solute carrier family 25 member 20

increases expression

Buspirone results in increased expression of SLC25A20 mRNA

NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512

G

solute carrier family 25 member 22

increases expression

Buspirone results in increased expression of SLC25A22 mRNA

NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331

G

solute carrier family 26 member 8

increases expression

Buspirone results in increased expression of SLC26A8 mRNA

NCBI chr20:6,686,206...6,749,478
Ensembl chr20:6,697,723...6,749,478

G

solute carrier family 27 member 5

increases expression

Buspirone results in increased expression of SLC27A5 mRNA

NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172

G

solute carrier family 28 member 2

decreases expression

Buspirone results in decreased expression of SLC28A2 mRNA

NCBI chr 3:109,324,815...109,387,702
Ensembl chr 3:109,366,996...109,387,702

G

solute carrier family 34 member 1

increases expression

Buspirone results in increased expression of SLC34A1 mRNA

NCBI chr17:9,218,876...9,233,852
Ensembl chr17:9,218,876...9,233,852

G

solute carrier family 34 member 2

decreases expression

Buspirone results in decreased expression of SLC34A2 mRNA

NCBI chr14:57,910,931...57,930,236
Ensembl chr14:57,910,480...57,930,436

G

solute carrier family 35 member B4

decreases expression

Buspirone results in decreased expression of SLC35B4 mRNA

NCBI chr 4:62,776,993...62,799,013
Ensembl chr 4:62,776,993...62,799,003

G

solute carrier family 37 member 4

increases expression

Buspirone results in increased expression of SLC37A4 mRNA

NCBI chr 8:44,723,216...44,729,301
Ensembl chr 8:44,723,339...44,729,301

G

solute carrier family 41 member 2

decreases expression

Buspirone results in decreased expression of SLC41A2 mRNA

NCBI chr 7:20,383,714...20,491,178
Ensembl chr 7:20,383,757...20,491,166

G

solute carrier family 49 member 4

increases expression

Buspirone results in increased expression of SLC49A4 mRNA

NCBI chr11:64,995,629...65,068,929
Ensembl chr11:64,995,679...65,068,926

G

solute carrier organic anion transporter family, member 1a4

increases expression

Buspirone results in increased expression of SLCO1A2 mRNA

NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573

G

schlafen family member 3

decreases expression

Buspirone results in decreased expression of SLFN3 mRNA

NCBI chr10:68,020,482...68,060,248

G

small integral membrane protein 26

increases expression

Buspirone results in increased expression of SMIM26 mRNA

NCBI chr 3:131,990,147...131,991,779
Ensembl chr 3:131,990,291...131,992,132

G

SPARC related modular calcium binding 1

increases expression

Buspirone results in increased expression of SMOC1 mRNA

NCBI chr 6:100,701,330...100,897,441
Ensembl chr 6:100,701,346...100,862,699

G

staphylococcal nuclease and tudor domain containing 1

decreases expression

Buspirone results in decreased expression of SND1 mRNA

NCBI chr 4:57,095,205...57,494,501
Ensembl chr 4:57,095,208...57,530,843

G

small nuclear ribonucleoprotein U11/U12 subunit 25

increases expression

Buspirone results in increased expression of SNRNP25 mRNA

NCBI chr10:15,420,482...15,423,806
Ensembl chr10:15,420,486...15,423,804

G

superoxide dismutase 3

decreases expression

Buspirone results in decreased expression of SOD3 mRNA

NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990

G

secreted protein acidic and cysteine rich

decreases expression

Buspirone results in decreased expression of SPARC mRNA

NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396

G

spartin

decreases expression

Buspirone results in decreased expression of SPART mRNA

NCBI chr 2:139,292,630...139,319,248
Ensembl chr 2:139,292,355...139,319,248

G

signal peptidase complex subunit 2

decreases expression

Buspirone results in decreased expression of SPCS2 mRNA

NCBI chr 1:154,163,724...154,183,152
Ensembl chr 1:154,163,724...154,183,186

G

SPG21 abhydrolase domain containing, maspardin

increases expression

Buspirone results in increased expression of SPG21 mRNA

NCBI chr 8:65,980,992...66,008,537
Ensembl chr 8:65,980,962...66,008,536

G

serine peptidase inhibitor, Kazal type 1

increases expression

Buspirone results in increased expression of SPINK1 mRNA

NCBI chr18:35,870,723...35,882,693
Ensembl chr18:35,824,550...35,882,642

G

SPNS lysolipid transporter 1, lysophospholipid

increases expression

Buspirone results in increased expression of SPNS1 mRNA

NCBI chr 1:180,942,088...180,949,415
Ensembl chr 1:180,942,088...180,949,370

G

serine palmitoyltransferase, small subunit A

increases expression

Buspirone results in increased expression of SPTSSA mRNA

NCBI chr 6:72,144,714...72,156,130
Ensembl chr 6:72,144,714...72,156,214

G

sterol regulatory element binding transcription factor 1

decreases expression

Buspirone results in decreased expression of SREBF1 mRNA

NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650

G

serglycin

decreases expression

Buspirone results in decreased expression of SRGN mRNA

NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406

G

signal recognition particle 72

decreases expression

Buspirone results in decreased expression of SRP72 mRNA

NCBI chr14:31,168,175...31,195,717
Ensembl chr14:31,168,293...31,195,729

G

SRP receptor subunit alpha

decreases expression

Buspirone results in decreased expression of SRPRA mRNA

NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470

G

SRP receptor subunit beta

decreases expression

Buspirone results in decreased expression of SRPRB mRNA

NCBI chr 8:103,768,685...103,782,632

G

serine/arginine repetitive matrix 2

increases expression

Buspirone results in increased expression of SRRM2 mRNA

NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751

G

serine and arginine rich splicing factor 2

decreases expression

Buspirone results in decreased expression of SRSF2 mRNA

NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338

G

serine and arginine rich splicing factor 3

decreases expression

Buspirone results in decreased expression of SRSF3 mRNA

NCBI chr20:7,091,928...7,101,860
Ensembl chr20:7,091,910...7,101,078

G

serine and arginine rich splicing factor 4

increases expression

Buspirone results in increased expression of SRSF4 mRNA

NCBI chr 5:144,060,981...144,090,798
Ensembl chr 5:144,061,463...144,089,229

G

signal sequence receptor subunit 1

decreases expression

Buspirone results in decreased expression of SSR1 mRNA

NCBI chr17:26,833,720...26,861,821
Ensembl chr17:26,833,741...26,861,821

G

SSX family member 2 interacting protein

decreases expression

Buspirone results in decreased expression of SSX2IP mRNA

NCBI chr 2:235,298,012...235,330,750
Ensembl chr 2:235,298,088...235,330,745

G

ST6 beta-galactoside alpha-2,6-sialyltransferase 1

decreases expression

Buspirone results in decreased expression of ST6GAL1 mRNA

NCBI chr11:77,526,837...77,653,474
Ensembl chr11:77,526,837...77,653,310

G

SH3 and cysteine rich domain 3

decreases expression

Buspirone results in decreased expression of STAC3 mRNA

NCBI chr 7:63,343,078...63,350,590
Ensembl chr 7:63,343,186...63,350,589

G

signal transducing adaptor family member 2

increases expression

Buspirone results in increased expression of STAP2 mRNA

NCBI chr 9:828,369...838,648
Ensembl chr 9:828,372...837,219

G

StAR-related lipid transfer domain containing 5

decreases expression

Buspirone results in decreased expression of STARD5 mRNA

NCBI chr 1:137,606,151...137,616,017
Ensembl chr 1:137,606,177...137,616,469

G

signal transducer and activator of transcription 1

decreases expression

Buspirone results in decreased expression of STAT1 mRNA

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

starch binding domain 1

increases expression

Buspirone results in increased expression of STBD1 mRNA

NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443

G

STEAP3 metalloreductase

decreases expression

Buspirone results in decreased expression of STEAP3 mRNA

NCBI chr13:31,351,954...31,397,344
Ensembl chr13:31,351,954...31,396,519

G

stathmin 1

decreases expression

Buspirone results in decreased expression of STMN1 mRNA

NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154

G

small ubiquitin-like modifier 3

decreases expression

Buspirone results in decreased expression of SUMO3 mRNA

NCBI chr20:11,010,140...11,020,850
Ensembl chr20:11,007,148...11,020,877
Ensembl chr20:11,007,148...11,020,877

G

Sad1 and UNC84 domain containing 2

increases expression

Buspirone results in increased expression of SUN2 mRNA

NCBI chr 7:111,275,374...111,292,565
Ensembl chr 7:111,275,380...111,292,553

G

small VCP interacting protein

increases expression

Buspirone results in increased expression of SVIP mRNA

NCBI chr 1:101,587,128...101,592,818
Ensembl chr 1:101,587,128...101,593,116

G

transgelin 2

decreases expression

Buspirone results in decreased expression of TAGLN2 mRNA

NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972

G

threonyl-tRNA synthetase 1

decreases expression

Buspirone results in decreased expression of TARS1 mRNA

NCBI chr 2:60,368,893...60,387,715
Ensembl chr 2:60,367,796...60,387,717

G

transcription elongation regulator 1

decreases expression

Buspirone results in decreased expression of TCERG1 mRNA

NCBI chr18:34,505,708...34,566,470
Ensembl chr18:34,505,751...34,566,470

G

T-cell immune regulator 1, ATPase H+ transporting V0 subunit A3

decreases expression

Buspirone results in decreased expression of TCIRG1 mRNA

NCBI chr 1:201,127,034...201,138,787
Ensembl chr 1:201,127,034...201,138,742

G

T-cell leukemia translocation altered

increases expression

Buspirone results in increased expression of TCTA mRNA

NCBI chr 8:108,988,588...108,992,324
Ensembl chr 8:108,988,590...108,991,564

G

tryptophan 2,3-dioxygenase

increases expression

Buspirone results in increased expression of TDO2 mRNA

NCBI chr