Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:4H-chromene
go back to main search page
Accession:CHEBI:35603 term browser browse the term
Definition:A simplest member of the class of chromene in which the heterocyclic pyran ring has a double bond between positions 2 and 3.
Synonyms:related_synonym: 4H-1-benzopyran;   Formula=C9H8O;   InChI=1S/C9H8O/c1-2-6-9-8(4-1)5-3-7-10-9/h1-4,6-7H,5H2;   InChIKey=JCIDEANDDNSHQC-UHFFFAOYSA-N;   SMILES=C1C=COc2ccccc12
 xref: Beilstein:111589;   CAS:254-03-5
 cyclic_relationship: is_tautomer_of CHEBI:35601



show annotations for term's descendants           Sort by:
 
anthocyanin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions
decreases expression
ISO
EXP
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein]
Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of ACTA2 protein]
Anthocyanins results in decreased expression of ACTA2 mRNA; Anthocyanins results in decreased expression of ACTA2 protein
CTD PMID:30056145 PMID:30403199 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of AGER protein] CTD PMID:24795233 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Atm ATM serine/threonine kinase increases phosphorylation ISO Anthocyanins results in increased phosphorylation of ATM protein CTD PMID:27444805 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G B2m beta-2 microglobulin multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of B2M protein] CTD PMID:30825423 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BAD protein modified form]; Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAD protein] CTD PMID:28856781 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of BAK1 protein] CTD PMID:28856781 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of BAX protein] CTD PMID:30403199 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; Anthocyanins inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2 protein] CTD PMID:28856781 PMID:30403199 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in decreased expression of BCL2L1 protein] CTD PMID:28856781 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Car1 carbonic anhydrase 1 decreases activity ISO Anthocyanins results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO Anthocyanins results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Casp1 caspase 1 multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased activity of CASP1 protein] CTD PMID:24795233 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of CASP3 protein] CTD PMID:28856781 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP8 protein] CTD PMID:28856781 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of CASP9 protein] CTD PMID:28856781 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:30825423 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of CCL2 protein] CTD PMID:30056145 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Anthocyanins results in decreased expression of CCN2 mRNA CTD PMID:30056145 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccnb1 cyclin B1 increases expression
multiple interactions
ISO Anthocyanins results in increased expression of CCNB1 protein
Anthocyanins promotes the reaction [CDK1 protein binds to CCNB1 protein]
CTD PMID:27444805 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Cdc25c cell division cycle 25C multiple interactions
increases phosphorylation
ISO Anthocyanins results in decreased expression of and results in increased phosphorylation of CDC25C protein
Anthocyanins results in increased phosphorylation of CDC25C protein
CTD PMID:27444805 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
JBrowse link
G Cdh1 cadherin 1 multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in decreased expression of CDH1 protein] CTD PMID:30403199 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdk1 cyclin-dependent kinase 1 multiple interactions ISO Anthocyanins promotes the reaction [CDK1 protein binds to CCNB1 protein]; Anthocyanins results in increased expression of and results in increased phosphorylation of CDK1 protein CTD PMID:27444805 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Anthocyanins results in increased expression of CDKN1A protein CTD PMID:27444805 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Anthocyanins results in increased expression of CDKN1B protein CTD PMID:27444805 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Chek1 checkpoint kinase 1 increases phosphorylation ISO Anthocyanins results in increased phosphorylation of CHEK1 protein CTD PMID:27444805 NCBI chr 8:36,420,565...36,443,477 JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation ISO Anthocyanins results in increased phosphorylation of CHEK2 protein CTD PMID:27444805 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Cldn4 claudin 4 multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of CLDN4 protein] CTD PMID:25451569 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased expression of COL1A1 mRNA] CTD PMID:30403199 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of COL3A1 protein] CTD PMID:30056145 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Ctsd cathepsin D multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of CTSD protein] CTD PMID:25451569 NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of CXCL2] CTD PMID:30056145 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases expression EXP Anthocyanins results in increased expression of CYP2C mRNA CTD PMID:18803703 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases expression EXP Anthocyanins results in increased expression of CYP2E1 mRNA CTD PMID:18803703 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP Anthocyanins results in increased expression of CYP3A2 mRNA CTD PMID:18803703 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Anthocyanins results in increased expression of CYP3A23-3A1 mRNA CTD PMID:18803703 NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
JBrowse link
G Fadd Fas associated via death domain multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FADD protein] CTD PMID:28856781 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FAS protein] CTD PMID:28856781 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased expression of FASLG protein] CTD PMID:28856781 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased activity of GSR protein] CTD PMID:30825423 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gusb glucuronidase, beta multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of GUSB protein] CTD PMID:25451569 NCBI chr12:26,701,191...26,714,718
Ensembl chr12:26,697,951...26,726,905
JBrowse link
G H2ax H2A.X variant histone increases phosphorylation ISO Anthocyanins results in increased phosphorylation of H2AX protein CTD PMID:27444805 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of HAVCR1 protein] CTD PMID:30825423 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Ikbkb inhibitor of nuclear factor kappa B kinase subunit beta multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased phosphorylation of IKBKB protein] CTD PMID:24795233 NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250
JBrowse link
G Il10 interleukin 10 multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of IL10 protein] CTD PMID:25451569 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP
ISO
Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of IL1B protein]
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of IL1B protein]; Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of IL1B protein]
CTD PMID:24795233 PMID:25451569 PMID:30056145 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Lcn2 lipocalin 2 multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of LCN2 protein] CTD PMID:30825423 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in decreased expression of MMP9 protein] CTD PMID:30056145 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased activity of MPO protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of MPO protein] CTD PMID:25451569 PMID:30825423 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased degradation of NFKBIA protein] CTD PMID:24795233 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of NLRP3 protein] CTD PMID:24795233 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of NOS2 protein] CTD PMID:24795233 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein] CTD PMID:28856781 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of PCNA protein] CTD PMID:30056145 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO Anthocyanins results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 increases expression EXP Anthocyanins results in increased expression of PIK3R1 mRNA CTD PMID:18803703 NCBI chr 2:32,878,942...32,963,611
Ensembl chr 2:32,882,032...32,963,631
JBrowse link
G Pla2g2a phospholipase A2 group IIA increases expression EXP Anthocyanins results in increased expression of PLA2G2A mRNA CTD PMID:18803703 NCBI chr 5:151,076,442...151,079,019
Ensembl chr 5:151,076,442...151,079,014
JBrowse link
G Plcd4 phospholipase C, delta 4 increases expression EXP Anthocyanins results in increased expression of PLCD4 mRNA CTD PMID:18803703 NCBI chr 9:76,115,523...76,158,602
Ensembl chr 9:76,117,168...76,142,453
JBrowse link
G Por cytochrome p450 oxidoreductase increases expression EXP Anthocyanins results in increased expression of POR mRNA CTD PMID:18803703 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of PTGS2 protein] CTD PMID:24795233 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of PYCARD protein] CTD PMID:24795233 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in increased activity of RELA protein] CTD PMID:25451569 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Smad2 SMAD family member 2 multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased phosphorylation of SMAD2 protein] CTD PMID:30403199 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Snca synuclein alpha decreases expression ISO Anthocyanins results in decreased expression of SNCA protein CTD PMID:29976995 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases expression
multiple interactions
ISO
EXP
Anthocyanins results in decreased expression of TGFB1 mRNA
Anthocyanins inhibits the reaction [Paraquat results in increased expression of TGFB1 protein]
CTD PMID:30056145 PMID:30403199 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased expression of TGFBR1 protein] CTD PMID:30403199 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions ISO Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 protein] CTD PMID:30056145 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tjp1 tight junction protein 1 multiple interactions EXP Anthocyanins inhibits the reaction [Cyclophosphamide results in decreased expression of TJP1 protein] CTD PMID:25451569 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
JBrowse link
G Tnf tumor necrosis factor multiple interactions EXP
ISO
Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; Anthocyanins inhibits the reaction [Cyclophosphamide results in increased expression of TNF protein]
Anthocyanins inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
CTD PMID:18720166 PMID:25451569 PMID:30825423 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txnip thioredoxin interacting protein multiple interactions ISO Anthocyanins inhibits the reaction [Dietary Fats results in increased expression of TXNIP protein] CTD PMID:24795233 NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
JBrowse link
G Vim vimentin multiple interactions EXP Anthocyanins inhibits the reaction [Paraquat results in increased expression of VIM mRNA]; Anthocyanins inhibits the reaction [Paraquat results in increased expression of VIM protein] CTD PMID:30403199 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xdh xanthine dehydrogenase multiple interactions EXP Anthocyanins inhibits the reaction [Carbon Tetrachloride results in increased activity of XDH protein] CTD PMID:30825423 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link
cyanidin cation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity ISO cyanidin results in increased activity of AHR protein CTD PMID:23419638 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Ccn1 cellular communication network factor 1 multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CCN1 protein]
CTD PMID:32044269 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions EXP
ISO
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of CSF2 protein]
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]
CTD PMID:32044269 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO cyanidin inhibits the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] CTD PMID:26800359 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hlcs holocarboxylase synthetase decreases activity ISO cyanidin results in decreased activity of HLCS protein CTD PMID:26303405 NCBI chr11:33,455,806...33,635,197
Ensembl chr11:33,455,809...33,624,222
JBrowse link
G Hmox1 heme oxygenase 1 affects expression ISO cyanidin affects the expression of HMOX1 protein CTD PMID:26505893 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Il17a interleukin 17A multiple interactions ISO [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CCN1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of CSF2 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]] CTD PMID:32044269 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
JBrowse link
G Il17ra interleukin 17 receptor A multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL17RA protein] CTD PMID:32044269 NCBI chr 4:153,667,534...153,690,174
Ensembl chr 4:153,667,534...153,690,174
JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A mRNA]; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of IL23A protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of IL23A protein]
CTD PMID:32044269 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Jak1 Janus kinase 1 multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK1 protein] CTD PMID:32044269 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
JBrowse link
G Jak3 Janus kinase 3 multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased phosphorylation of JAK3 protein] CTD PMID:32044269 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases activity
affects expression
EXP
ISO
cyanidin results in increased activity of NFE2L2 protein
cyanidin affects the expression of NFE2L2 protein
CTD PMID:26505893 PMID:27166148 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos3 nitric oxide synthase 3 increases expression ISO cyanidin results in increased expression of NOS3 mRNA CTD PMID:15740983 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of PCNA protein] CTD PMID:32044269 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pias3 protein inhibitor of activated STAT, 3 multiple interactions ISO [cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein CTD PMID:32044269 NCBI chr 2:184,232,546...184,241,455
Ensembl chr 2:184,232,571...184,241,480
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO
EXP
[cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]] which results in increased expression of PIAS3 protein; cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of and results in increased phosphorylation of STAT3 protein]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased phosphorylation of STAT3 protein]
CTD PMID:32044269 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO
EXP
cyanidin inhibits the reaction [[IL17A protein co-treated with Freund's Adjuvant] results in increased expression of TLR3 protein]; cyanidin inhibits the reaction [IL17A protein promotes the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]]
cyanidin inhibits the reaction [Freund's Adjuvant results in increased expression of TLR3 protein]
CTD PMID:32044269 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of TNF mRNA] CTD PMID:28533128 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Ucp2 uncoupling protein 2 multiple interactions ISO cyanidin inhibits the reaction [Benzo(a)pyrene results in increased expression of UCP2 mRNA] CTD PMID:28533128 NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO cyanidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein]; cyanidin inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA] CTD PMID:16921400 PMID:26800359 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
delphinidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:20371262 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of ARNT protein] CTD PMID:18603805 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO delphinidin results in increased expression of BAD protein CTD PMID:33955636 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression ISO delphinidin results in increased expression of BAK1 protein CTD PMID:29451351 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
decreases expression
ISO delphinidin results in increased expression of BAX protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]]; delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]
delphinidin results in decreased expression of BAX protein
CTD PMID:15740068 PMID:19818742 PMID:30365941 PMID:33955636 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases expression
ISO delphinidin results in decreased expression of BCL2 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]]; delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]
delphinidin results in increased expression of BCL2 protein
CTD PMID:15740068 PMID:19818742 PMID:29451351 PMID:30365941 PMID:33955636 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression ISO delphinidin results in decreased expression of BCL2L1 protein CTD PMID:33955636 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in decreased expression of BID protein CTD PMID:30125548 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Btg2 BTG anti-proliferation factor 2 affects expression ISO delphinidin affects the expression of BTG2 mRNA CTD PMID:19182879 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
JBrowse link
G Casp3 caspase 3 increases activity
increases expression
increases cleavage
multiple interactions
ISO delphinidin results in increased activity of CASP3 protein
delphinidin results in increased expression of CASP3 protein
delphinidin results in increased cleavage of CASP3 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]]; [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP3 protein; delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]
CTD PMID:15740068 PMID:29451351 PMID:30125548 PMID:30365941 PMID:33955636 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions
increases expression
ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP8 protein
delphinidin results in increased expression of CASP8 protein
CTD PMID:30125548 PMID:33955636 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases expression
ISO [delphinidin results in increased susceptibility to sodium arsenite] which results in increased cleavage of CASP9 protein
delphinidin results in increased expression of CASP9 protein
CTD PMID:30125548 PMID:33955636 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase decreases activity ISO delphinidin results in decreased activity of CAT protein CTD PMID:33955636 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cdh1 cadherin 1 increases expression ISO delphinidin results in increased expression of CDH1 protein CTD PMID:29451351 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 decreases expression ISO delphinidin results in decreased expression of CDH2 protein CTD PMID:29451351 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cidea cell death-inducing DFFA-like effector a increases expression ISO delphinidin results in increased expression of CIDEA mRNA CTD PMID:19182879 NCBI chr18:60,894,917...60,920,485
Ensembl chr18:60,894,874...60,920,481
JBrowse link
G Cycs cytochrome c, somatic increases expression ISO delphinidin results in increased expression of CYCS protein CTD PMID:33955636 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO delphinidin results in decreased activity of CYP1A1 protein CTD PMID:23419638 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation ISO delphinidin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
JBrowse link
G Epas1 endothelial PAS domain protein 1 multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of ERBB2 protein CTD PMID:18618485 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF1A protein] CTD PMID:18603805 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hif3a hypoxia inducible factor 3 subunit alpha multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of HIF3A protein] CTD PMID:18603805 NCBI chr 1:77,718,110...77,750,448
Ensembl chr 1:77,722,471...77,749,758
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP delphinidin results in increased expression of HMOX1 protein CTD PMID:30266311 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Jak2 Janus kinase 2 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of JAK2 protein CTD PMID:33955636 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO delphinidin results in increased expression of JUN mRNA CTD PMID:15740068 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of MAPK1 protein CTD PMID:18618485 PMID:29451351 PMID:33955636 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of MAPK3 protein CTD PMID:18618485 PMID:29451351 PMID:33955636 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO delphinidin results in increased phosphorylation of and results in increased activity of MAPK8 protein CTD PMID:15740068 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO delphinidin promotes the reaction [Carbon Tetrachloride results in increased expression of MMP9 protein] CTD PMID:20371262 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Nbn nibrin increases expression ISO delphinidin results in increased expression of NBN mRNA CTD PMID:19182879 NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 decreases activity
increases cleavage
ISO delphinidin results in decreased activity of PARP1 protein
delphinidin results in increased cleavage of PARP1 protein
CTD PMID:17884996 PMID:29451351 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcbp4 poly(rC) binding protein 4 affects expression ISO delphinidin affects the expression of PCBP4 mRNA CTD PMID:19182879 NCBI chr 8:107,092,688...107,103,276
Ensembl chr 8:107,093,013...107,103,276
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Pgk1 phosphoglycerate kinase 1 multiple interactions ISO delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of PGK1 protein] CTD PMID:18603805 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418
JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO delphinidin results in decreased expression of SNAI1 protein CTD PMID:29451351 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 decreases expression ISO delphinidin results in decreased expression of SNAI2 protein CTD PMID:29451351 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link
G Stat3 signal transducer and activator of transcription 3 decreases phosphorylation ISO delphinidin results in decreased phosphorylation of STAT3 protein CTD PMID:33955636 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]]; delphinidin inhibits the reaction [TGFB1 results in decreased expression of BCL2 protein]; delphinidin inhibits the reaction [TGFB1 results in increased abundance of Malondialdehyde]; delphinidin inhibits the reaction [TGFB1 results in increased abundance of Reactive Oxygen Species]; delphinidin inhibits the reaction [TGFB1 results in increased expression of CASP3 protein]; delphinidin promotes the reaction [TGFB1 results in decreased expression of BAX protein]
CTD PMID:20371262 PMID:30365941 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO delphinidin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein] CTD PMID:20371262 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Top1 DNA topoisomerase I decreases activity ISO delphinidin results in decreased activity of TOP1 protein CTD PMID:19182879 NCBI chr 3:149,293,658...149,375,405
Ensembl chr 3:149,293,403...149,376,623
JBrowse link
G Top2a DNA topoisomerase II alpha decreases activity
multiple interactions
ISO delphinidin results in decreased activity of TOP2A protein
delphinidin results in decreased susceptibility to [Doxorubicin affects the activity of TOP2A protein]; delphinidin results in decreased susceptibility to [Etoposide affects the activity of TOP2A protein]
CTD PMID:19182879 NCBI chr10:83,946,186...83,975,694
Ensembl chr10:83,945,735...83,976,874
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO delphinidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased secretion of VEGFA protein] CTD PMID:16921400 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
luteolinidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression EXP luteolinidin results in increased expression of HSD17B7 mRNA CTD PMID:31201582 NCBI chr13:82,170,079...82,190,018
Ensembl chr13:82,173,179...82,190,017
JBrowse link
G Nfe2 nuclear factor, erythroid 2 increases expression EXP luteolinidin results in increased expression of NFE2 mRNA CTD PMID:31201582 NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108
JBrowse link
malvidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:23755222 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO malvidin results in increased expression of BAX protein CTD PMID:15964118 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO malvidin results in decreased expression of BCL2 protein CTD PMID:15964118 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
ISO malvidin results in increased activity of CASP3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [malvidin results in increased activity of CASP3 protein]; SB 203580 inhibits the reaction [malvidin results in increased activity of CASP3 protein]
CTD PMID:15964118 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Dusp1 dual specificity phosphatase 1 multiple interactions ISO malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 mRNA]; malvidin promotes the reaction [endotoxin, Escherichia coli results in increased expression of DUSP1 protein] CTD PMID:23755222 NCBI chr10:16,680,489...16,683,276 JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO malvidin promotes the reaction [[endotoxin, Escherichia coli results in increased phosphorylation of and results in increased activity of AKT1 protein] which results in increased phosphorylation of GSK3B protein] CTD PMID:23755222 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation ISO malvidin results in decreased phosphorylation of MAPK1 protein CTD PMID:15964118 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO malvidin results in increased expression of and results in increased phosphorylation of MAPK14 protein CTD PMID:15964118 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation ISO malvidin results in decreased phosphorylation of MAPK3 protein CTD PMID:15964118 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO malvidin results in increased cleavage of PARP1 protein CTD PMID:15964118 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO malvidin results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO malvidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO malvidin inhibits the reaction [endotoxin, Escherichia coli affects the localization of and results in increased phosphorylation of and results in increased activity of RELA protein] CTD PMID:23755222 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
malvidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:23731018 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Pde5a phosphodiesterase 5A decreases activity ISO malvidin-3-glucoside results in decreased activity of PDE5A protein CTD PMID:15769121 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Sele selectin E multiple interactions ISO malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein] CTD PMID:30611791 NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO malvidin-3-glucoside inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
malvidin-3-glucoside inhibits the reaction [TNF protein results in increased expression of SELE protein]
CTD PMID:23731018 PMID:30611791 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
malvin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO malvin results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO malvin results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
pelargonidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor increases activity
multiple interactions
ISO pelargonidin metabolite results in increased activity of AHR protein
[pelargonidin metabolite results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; pelargonidin binds to and results in increased activity of AHR protein
CTD PMID:23419638 PMID:23735880 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CDH1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CDH1 protein] CTD PMID:30753810 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
multiple interactions
ISO pelargonidin metabolite results in decreased activity of CYP1A1 protein; pelargonidin results in decreased activity of CYP1A1 protein
pelargonidin metabolite results in increased expression of CYP1A1 mRNA; pelargonidin results in increased expression of CYP1A1 mRNA
[pelargonidin metabolite results in increased activity of AHR protein] which results in increased expression of CYP1A1 mRNA; pelargonidin results in increased expression of and results in increased activity of CYP1A1 protein
CTD PMID:23419638 PMID:23735880 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO pelargonidin results in increased expression of CYP1A2 mRNA CTD PMID:23419638 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Dnmt1 DNA methyltransferase 1 decreases expression ISO pelargonidin results in decreased expression of DNMT1 protein CTD PMID:31181187 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta decreases expression ISO pelargonidin results in decreased expression of DNMT3B protein CTD PMID:31181187 NCBI chr 3:142,130,592...142,169,124
Ensembl chr 3:142,130,592...142,169,124
JBrowse link
G Hdac1 histone deacetylase 1 decreases expression ISO pelargonidin results in decreased expression of HDAC1 protein CTD PMID:31181187 NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
JBrowse link
G Hdac2 histone deacetylase 2 decreases expression ISO pelargonidin results in decreased expression of HDAC2 protein CTD PMID:31181187 NCBI chr20:40,548,250...40,571,609
Ensembl chr20:40,548,250...40,571,609
JBrowse link
G Hdac3 histone deacetylase 3 decreases expression ISO pelargonidin results in decreased expression of HDAC3 protein CTD PMID:31181187 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856
JBrowse link
G Hdac4 histone deacetylase 4 decreases expression ISO pelargonidin results in decreased expression of HDAC4 protein CTD PMID:31181187 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Hdac7 histone deacetylase 7 decreases expression ISO pelargonidin results in decreased expression of HDAC7 protein CTD PMID:31181187 NCBI chr 7:128,923,918...128,962,025
Ensembl chr 7:128,923,920...128,962,072
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO pelargonidin results in increased expression of HMOX1 mRNA; pelargonidin results in increased expression of HMOX1 protein CTD PMID:31181187 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of ICAM1 protein] CTD PMID:30753810 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Il6 interleukin 6 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein] CTD PMID:30753810 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein] CTD PMID:30753810 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein] CTD PMID:30753810 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases methylation
affects response to substance
ISO pelargonidin results in decreased methylation of NFE2L2 promoter
NFE2L2 protein affects the susceptibility to pelargonidin
CTD PMID:31181187 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:18274639 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO pelargonidin results in increased expression of NQO1 mRNA; pelargonidin results in increased expression of NQO1 protein CTD PMID:31181187 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA] CTD PMID:21341175 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein]
pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of RELA protein]
CTD PMID:18274639 PMID:30753810 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TLR4 protein] CTD PMID:30753810 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO pelargonidin inhibits the reaction [Lipopolysaccharides results in increased expression of TNF]
pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]
CTD PMID:18720166 PMID:30753810 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases activity EXP pelargonidin results in decreased activity of TXNRD1 protein modified form CTD PMID:16618767 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 mRNA]; pelargonidin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of VCAM1 protein] CTD PMID:30753810 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
JBrowse link
pelargonidin 3-O-beta-D-glucoside term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
pelargonidin 3-O-beta-D-glucoside chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Car1 carbonic anhydrase 1 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA1 protein CTD PMID:28445001 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases activity ISO pelargonidin-3-glucoside results in decreased activity of CA2 protein CTD PMID:28445001 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
peonidin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link
peonidin chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdgfa platelet derived growth factor subunit A multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pdgfb platelet derived growth factor subunit B multiple interactions ISO peonidin inhibits the reaction [[PDGFA protein co-treated with PDGFB protein] results in increased abundance of Reactive Oxygen Species] CTD PMID:16921400 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    chemical entity 19795
      molecular entity 19794
        mancude ring 8562
          organic mancude parent 8562
            mancude organic heterocyclic parent 8562
              mancude organic heterobicyclic parent 5415
                chromene 136
                  4H-chromene 136
                    chromenyliums + 136
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    p-block element atom 19693
                      carbon group element atom 19614
                        carbon atom 19604
                          organic molecular entity 19604
                            organic molecule 19545
                              organic cyclic compound 19339
                                organic heterocyclic compound 18579
                                  oxacycle 17602
                                    benzopyran 11160
                                      1-benzopyran 10901
                                        chromenes 3027
                                          chromene 136
                                            4H-chromene 136
                                              chromenyliums + 136
paths to the root