4H-pyran - Ontology Report - Rat Genome Database

Submit Data | Help | Video Tutorials | News | Publications | Download | REST API | Citing RGD | Contact

CHEBI ONTOLOGY - ANNOTATIONS

{{ watchLinkText }}

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	4H-pyran	go back to main search page
Accession:	CHEBI:35593	browse the term
Definition:	A pyran that has formula C5H6O.
Synonyms:	related_synonym:	Formula=C5H6O; InChI=1S/C5H6O/c1-2-4-6-5-3-1/h2-5H,1H2; InChIKey=MRUWJENAYHTDQG-UHFFFAOYSA-N; SMILES=C1C=COC=C1
	xref:	Beilstein:1421312; CAS:289-65-6
	cyclic_relationship:	is_tautomer_of CHEBI:35592

show annotations for term's descendants Sort by:
Rat (422) Mouse (420) Human (431) Chinchilla (0) Bonobo (0) Dog (0) Squirrel (0) Pig (0) Green Monkey (0) Naked Mole-rat (0) All
Genes (431)

kojic acid

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily A member 11, pseudogene

decreases expression

kojic acid results in decreased expression of ABCA11P mRNA

NCBI chr 4:425,435...474,209
Ensembl chr 4:425,773...427,882
Ensembl chr 4:425,773...427,882

G

ATP binding cassette subfamily A member 13

decreases expression

kojic acid results in decreased expression of ABCA13 mRNA

NCBI chr 7:48,171,458...48,647,497
Ensembl chr 7:48,171,458...48,647,497

G

ATP binding cassette subfamily C member 13 (pseudogene)

decreases expression

kojic acid results in decreased expression of ABCC13 mRNA

NCBI chr21:14,273,799...14,301,386
Ensembl chr21:14,236,206...14,338,017
Ensembl chr21:14,236,206...14,338,017

G

ATP binding cassette subfamily C member 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of ABCC2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC2 mRNA

NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594

G

ATP binding cassette subfamily C member 6

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCC6 mRNA
[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABCC6 mRNA

PMID:17917374 PMID:18544905

NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522

G

ATP binding cassette subfamily C member 9

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCC9 mRNA

NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543

G

ATP binding cassette subfamily D member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCD1 mRNA

NCBI chr X:153,724,856...153,744,755
Ensembl chr X:153,724,856...153,744,755

G

ATP binding cassette subfamily F member 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of ABCF2 mRNA

NCBI chr 7:151,211,484...151,227,205
Ensembl chr 7:151,211,484...151,227,205

G

abhydrolase domain containing 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of ABHD1 mRNA

NCBI chr 2:27,123,815...27,130,812
Ensembl chr 2:27,123,789...27,130,812

G

alkaline ceramidase 3

increases expression

kojic acid results in increased expression of ACER3 mRNA

NCBI chr11:76,860,918...77,026,797
Ensembl chr11:76,860,859...77,026,797

G

aminocarboxymuconate semialdehyde decarboxylase

decreases expression

kojic acid results in decreased expression of ACMSD mRNA

NCBI chr 2:134,838,616...134,902,034
Ensembl chr 2:134,838,616...134,902,034

G

activin A receptor like type 1

decreases expression

kojic acid results in decreased expression of ACVRL1 mRNA

NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361

G

ADAM metallopeptidase domain 20

decreases expression

kojic acid results in decreased expression of ADAM20 mRNA

NCBI chr14:70,522,358...70,579,452
Ensembl chr14:70,522,358...70,535,015

G

adrenoceptor beta 3

decreases expression

kojic acid results in decreased expression of ADRB3 mRNA

NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599

G

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

increases expression

kojic acid results in increased expression of AGAP3 mRNA

NCBI chr 7:151,085,867...151,144,434
Ensembl chr 7:151,085,831...151,144,436

G

AGBL carboxypeptidase 4

decreases expression

kojic acid results in decreased expression of AGBL4 mRNA

NCBI chr 1:48,522,511...50,023,954
Ensembl chr 1:48,532,854...50,023,954

G

AHNAK nucleoprotein

decreases expression

kojic acid results in decreased expression of AHNAK mRNA

NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235

G

AKT serine/threonine kinase 1

decreases expression

kojic acid results in decreased expression of AKT1 mRNA

NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751

G

alkaline phosphatase, intestinal

decreases expression

kojic acid results in decreased expression of ALPI mRNA

NCBI chr 2:232,456,153...232,460,753
Ensembl chr 2:232,456,125...232,460,753

G

amelotin

decreases expression

kojic acid results in decreased expression of AMTN mRNA

NCBI chr 4:70,518,569...70,532,743
Ensembl chr 4:70,518,569...70,532,743

G

annexin A1

decreases expression

kojic acid results in decreased expression of ANXA1 mRNA

NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393

G

annexin A5

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ANXA5 mRNA

NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995

G

adaptor related protein complex 1 subunit sigma 1

decreases expression

kojic acid results in decreased expression of AP1S1 mRNA

NCBI chr 7:101,154,476...101,161,276
Ensembl chr 7:101,154,456...101,161,596

G

apolipoprotein B mRNA editing enzyme catalytic subunit 1

decreases expression

kojic acid results in decreased expression of APOBEC1 mRNA

NCBI chr12:7,649,400...7,670,599
Ensembl chr12:7,649,400...7,665,908

G

amyloid beta precursor protein

increases expression

kojic acid results in increased expression of APP mRNA

NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128

G

aprataxin

decreases expression

kojic acid results in decreased expression of APTX mRNA

NCBI chr 9:32,972,616...33,025,120
Ensembl chr 9:32,886,601...33,025,130

G

aquaporin 1 (Colton blood group)

increases expression

kojic acid results in increased expression of AQP1 mRNA

NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517

G

ADP ribosylation factor interacting protein 2

decreases expression

kojic acid results in decreased expression of ARFIP2 mRNA

NCBI chr11:6,476,519...6,481,331
Ensembl chr11:6,474,683...6,481,479

G

Rho guanine nucleotide exchange factor 16

decreases expression

kojic acid results in decreased expression of ARHGEF16 mRNA

NCBI chr 1:3,454,665...3,481,113
Ensembl chr 1:3,454,665...3,481,113

G

ADP ribosylation factor like GTPase 6 interacting protein 5

increases expression

kojic acid results in increased expression of ARL6IP5 mRNA

NCBI chr 3:69,084,937...69,106,092
Ensembl chr 3:69,084,937...69,106,092

G

asparagine synthetase domain containing 1

decreases expression

kojic acid results in decreased expression of ASNSD1 mRNA

NCBI chr 2:189,661,459...189,670,831
Ensembl chr 2:189,661,385...189,670,831

G

activating transcription factor 6 beta

decreases expression

kojic acid results in decreased expression of ATF6B mRNA

NCBI chr 6:32,115,264...32,128,246
Ensembl chr 6:32,115,264...32,128,253

G

ATM serine/threonine kinase

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ATM mRNA

NCBI chr11:108,223,067...108,369,102
Ensembl chr11:108,222,823...108,369,102

G

beta-1,4-N-acetyl-galactosaminyltransferase 4

decreases expression

kojic acid results in decreased expression of B4GALNT4 mRNA

NCBI chr11:369,499...382,117
Ensembl chr11:369,499...382,117

G

BAG cochaperone 5

decreases expression

kojic acid results in decreased expression of BAG5 mRNA

NCBI chr14:103,556,551...103,562,657
Ensembl chr14:103,556,545...103,562,657

G

BCL2 related protein A1

increases expression

kojic acid results in increased expression of BCL2A1 mRNA

NCBI chr15:79,960,892...79,971,196
Ensembl chr15:79,960,892...79,971,196

G

BCL2 like 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of BCL2L2 mRNA

NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751

G

baculoviral IAP repeat containing 2

decreases expression

kojic acid results in decreased expression of BIRC2 mRNA

NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670

G

bone morphogenetic protein 5

decreases expression

kojic acid results in decreased expression of BMP5 mRNA

NCBI chr 6:55,753,653...55,875,590
Ensembl chr 6:55,753,653...55,875,590

G

BR serine/threonine kinase 1

decreases expression

kojic acid results in decreased expression of BRSK1 mRNA

NCBI chr19:55,283,997...55,312,562
Ensembl chr19:55,282,072...55,312,562

G

bone marrow stromal cell antigen 2

decreases expression

kojic acid results in decreased expression of BST2 mRNA

NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630

G

chromosome 1 open reading frame 131

decreases expression

kojic acid results in decreased expression of C1ORF131 mRNA

NCBI chr 1:231,223,765...231,241,175
Ensembl chr 1:231,223,763...231,241,187

G

chromosome 1 open reading frame 54

increases expression

kojic acid results in increased expression of C1ORF54 mRNA

NCBI chr 1:150,268,731...150,280,924
Ensembl chr 1:150,268,200...150,280,916

G

chromosome 1 open reading frame 87

decreases expression

kojic acid results in decreased expression of C1ORF87 mRNA

NCBI chr 1:59,990,394...60,073,770
Ensembl chr 1:59,987,269...60,073,770

G

carbonic anhydrase 13

increases expression

kojic acid results in increased expression of CAR13 mRNA

NCBI chr 8:85,245,458...85,284,073
Ensembl chr 8:85,220,587...85,284,073

G

carbonic anhydrase 14

increases expression

kojic acid results in increased expression of CA14 mRNA

NCBI chr 1:150,257,774...150,265,078
Ensembl chr 1:150,257,251...150,265,078

G

calcium binding protein 39 like

increases expression

kojic acid results in increased expression of CAB39L mRNA

NCBI chr13:49,308,650...49,444,064
Ensembl chr13:49,308,650...49,444,064

G

calreticulin

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CALR mRNA

NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489

G

caspase 4

multiple interactions

[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA; Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CASP4 mRNA]

NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366

G

caspase 8

multiple interactions

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CASP8 mRNA

NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836

G

catalase

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CAT mRNA

NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060

G

cell division cycle and apoptosis regulator 1

increases expression

kojic acid results in increased expression of CCAR1 mRNA

NCBI chr10:68,721,239...68,792,377
Ensembl chr10:68,721,012...68,792,377

G

coiled-coil domain containing 144A

decreases expression

kojic acid results in decreased expression of CCDC144A mRNA

NCBI chr17:16,666,717...16,777,881
Ensembl chr17:16,689,537...16,777,881

G

coiled-coil domain containing 50

increases expression

kojic acid results in increased expression of CCDC50 mRNA

NCBI chr 3:191,329,394...191,398,659
Ensembl chr 3:191,329,085...191,398,659

G

C-C motif chemokine ligand 21

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL21A mRNA

NCBI chr 9:34,709,005...34,710,136
Ensembl chr 9:34,709,005...34,710,136

G

C-C motif chemokine ligand 3

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCL3 mRNA

NCBI chr17:36,088,256...36,090,143
Ensembl chr17:36,088,256...36,090,169

G

cyclin B1

increases expression

kojic acid results in increased expression of CCNB1 mRNA

NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245

G

cyclin C

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNC mRNA

NCBI chr 6:99,542,387...99,568,814
Ensembl chr 6:99,542,387...99,568,825

G

cyclin D1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CCND1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCND1 mRNA

PMID:17917374 PMID:18544905

NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474

G

cyclin G1

multiple interactions

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of CCNG1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CCNG1 mRNA

PMID:17917374 PMID:18544905

NCBI chr 5:163,437,571...163,457,640
Ensembl chr 5:163,437,569...163,446,151

G

cell cycle progression 1

decreases expression

kojic acid results in decreased expression of CCPG1 mRNA

NCBI chr15:55,355,239...55,408,359
Ensembl chr15:55,340,032...55,408,510

G

C-C motif chemokine receptor 4

decreases expression

kojic acid results in decreased expression of CCR4 mRNA

NCBI chr 3:32,951,644...32,956,349
Ensembl chr 3:32,951,644...32,956,349

G

CD22 molecule

decreases expression

kojic acid results in decreased expression of CD22 mRNA

NCBI chr19:35,329,187...35,347,361
Ensembl chr19:35,319,261...35,347,361

G

CD274 molecule

increases expression

kojic acid results in increased expression of CD274 mRNA

NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566

G

CD3 gamma subunit of T-cell receptor complex

decreases expression

kojic acid results in decreased expression of CD3G mRNA

NCBI chr11:118,344,344...118,355,161
Ensembl chr11:118,344,344...118,355,161

G

CDAN1 interacting nuclease 1

increases expression

kojic acid results in increased expression of CDIN1 mRNA

NCBI chr15:36,579,626...36,810,244
Ensembl chr15:36,579,626...36,810,248

G

cyclin dependent kinase 10

decreases expression

kojic acid results in decreased expression of CDK10 mRNA

NCBI chr16:89,686,689...89,696,354
Ensembl chr16:89,680,737...89,696,354

G

cyclin dependent kinase inhibitor 1A

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CDKN1A mRNA
[Diethylnitrosamine co-treated with kojic acid] results in increased expression of CDKN1A mRNA

PMID:17917374 PMID:18544905

NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337

G

cyclin dependent kinase inhibitor 1B

multiple interactions

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA; [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CDKN1B mRNA

NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369

G

CEA cell adhesion molecule 1

decreases expression

kojic acid results in decreased expression of CEACAM1 mRNA

NCBI chr19:42,507,306...42,528,481
Ensembl chr19:42,507,304...42,561,234

G

CCAAT enhancer binding protein delta

increases expression

kojic acid results in increased expression of CEBPD mRNA

NCBI chr 8:47,736,913...47,738,164
Ensembl chr 8:47,736,913...47,738,164

G

centromere protein Q

decreases expression

kojic acid results in decreased expression of CENPQ mRNA

NCBI chr 6:49,463,370...49,493,107
Ensembl chr 6:49,463,370...49,493,107

G

centrosomal protein 192

increases expression

kojic acid results in increased expression of CEP192 mRNA

NCBI chr18:12,991,362...13,125,036
Ensembl chr18:12,991,362...13,125,052

G

centrosomal protein 72

increases expression

kojic acid results in increased expression of CEP72 mRNA

NCBI chr 5:612,340...676,616
Ensembl chr 5:612,340...667,168

G

carboxylesterase 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of CES1 mRNA

NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337

G

checkpoint kinase 2

multiple interactions

[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA; Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of CHEK2 mRNA]

NCBI chr22:28,687,743...28,741,834
Ensembl chr22:28,687,743...28,742,422

G

carbohydrate sulfotransferase 4

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CHST4 mRNA

NCBI chr16:71,526,120...71,538,748
Ensembl chr16:71,525,233...71,538,748

G

CBY1 interacting BAR domain containing 1

increases expression

kojic acid results in increased expression of CIBAR1 mRNA

NCBI chr 8:93,700,550...93,731,527
Ensembl chr 8:93,698,561...93,731,527

G

claudin 3

decreases expression

kojic acid results in decreased expression of CLDN3 mRNA

NCBI chr 7:73,768,997...73,770,270
Ensembl chr 7:73,768,997...73,770,270

G

claudin domain containing 2

decreases expression

kojic acid results in decreased expression of CLDND2 mRNA

NCBI chr19:51,366,739...51,369,003
Ensembl chr19:51,367,098...51,369,003

G

C-type lectin domain family 4 member C

decreases expression

kojic acid results in decreased expression of CLEC4C mRNA

NCBI chr12:7,729,383...7,749,541
Ensembl chr12:7,729,383...7,751,605

G

CXADR like membrane protein

decreases expression

kojic acid results in decreased expression of CLMP mRNA

NCBI chr11:123,069,872...123,195,248
Ensembl chr11:123,069,872...123,195,248

G

clusterin

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CLU mRNA

NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700

G

cornichon family member 1

increases expression

kojic acid results in increased expression of CNIH1 mRNA

NCBI chr14:54,423,561...54,441,374
Ensembl chr14:54,423,561...54,441,391

G

connector enhancer of kinase suppressor of Ras 2

decreases expression

kojic acid results in decreased expression of CNKSR2 mRNA

NCBI chr X:21,374,418...21,654,689
Ensembl chr X:21,372,801...21,654,695

G

collagen type XVII alpha 1 chain

decreases expression

kojic acid results in decreased expression of COL17A1 mRNA

NCBI chr10:104,031,286...104,085,880
Ensembl chr10:104,031,286...104,085,880

G

collagen type XXIV alpha 1 chain

decreases expression

kojic acid results in decreased expression of COL24A1 mRNA

NCBI chr 1:85,729,233...86,156,984
Ensembl chr 1:85,729,233...86,156,943

G

collagen like tail subunit of asymmetric acetylcholinesterase

increases expression

kojic acid results in increased expression of COLQ mRNA

NCBI chr 3:15,450,133...15,521,706
Ensembl chr 3:15,450,133...15,521,751

G

catechol-O-methyltransferase

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of COMT mRNA

NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975

G

COP9 signalosome subunit 2

decreases expression

kojic acid results in decreased expression of COPS2 mRNA

NCBI chr15:49,122,727...49,155,599
Ensembl chr15:49,106,068...49,155,661

G

coenzyme Q10A

increases expression

kojic acid results in increased expression of COQ10A mRNA

NCBI chr12:56,266,942...56,270,966
Ensembl chr12:56,266,890...56,270,966

G

coenzyme Q8A

increases expression

kojic acid results in increased expression of COQ8A mRNA

NCBI chr 1:226,940,294...226,987,544
Ensembl chr 1:226,940,286...226,987,544

G

carboxypeptidase B1

decreases expression

kojic acid results in decreased expression of CPB1 mRNA

NCBI chr 3:148,827,811...148,860,187
Ensembl chr 3:148,791,102...148,860,187

G

carboxypeptidase E

increases expression

kojic acid results in increased expression of CPE mRNA

NCBI chr 4:165,379,008...165,498,547
Ensembl chr 4:165,361,194...165,498,547

G

copine 5

increases expression

kojic acid results in increased expression of CPNE5 mRNA

NCBI chr 6:36,740,775...36,839,998
Ensembl chr 6:36,740,775...36,839,444

G

cAMP responsive element binding protein 1

decreases phosphorylation

kojic acid results in decreased phosphorylation of CREB1 protein

NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988

G

chromosome segregation 1 like

decreases expression

kojic acid results in decreased expression of CSE1L mRNA

NCBI chr20:49,046,312...49,096,949
Ensembl chr20:49,046,246...49,096,960

G

catenin alpha like 1

decreases expression

kojic acid results in decreased expression of CTNNAL1 mRNA

NCBI chr 9:108,942,577...109,013,499
Ensembl chr 9:108,942,569...109,013,522

G

cathepsin Z

increases expression

kojic acid results in increased expression of CTSZ mRNA

NCBI chr20:58,995,185...59,007,254
Ensembl chr20:58,985,686...59,008,238

G

cytochrome b5 reductase 3

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYB5R3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYB5R3 mRNA

NCBI chr22:42,617,840...42,649,392
Ensembl chr22:42,615,730...42,720,870

G

cytochrome P450 family 26 subfamily B member 1

increases expression

kojic acid results in increased expression of CYP26B1 mRNA

NCBI chr 2:72,129,238...72,147,862
Ensembl chr 2:72,129,238...72,147,862

G

cytochrome P450 family 2 subfamily A member 6

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2A5 mRNA

NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447

G

cytochrome P450 family 2 subfamily B member 6

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP2B10 mRNA

NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398

G

cytochrome P450 family 2 subfamily C member 18

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2C mRNA

NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190

G

cytochrome P450 family 2 subfamily D member 6

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2D22 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2D22 mRNA

NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865

G

cytochrome P450 family 2 subfamily E member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2E1 mRNA

NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220

G

cytochrome P450 family 2 subfamily F member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP2F2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP2F2 mRNA

NCBI chr19:41,114,432...41,128,381
Ensembl chr19:41,114,432...41,128,381

G

cytochrome P450 family 4 subfamily A member 22

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4A22 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP4A22 mRNA

NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727

G

cytochrome P450 family 4 subfamily B member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of CYP4B1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4B1 mRNA

PMID:17917374 PMID:18544905

NCBI chr 1:46,799,046...46,819,413
Ensembl chr 1:46,757,838...46,819,413

G

cytochrome P450 family 4 subfamily F member 12

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP4F2 mRNA

NCBI chr19:15,673,087...15,697,174
Ensembl chr19:15,673,018...15,697,174

G

cytochrome P450 family 7 subfamily A member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP7A1 mRNA

NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163

G

cytochrome P450 family 8 subfamily B member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of CYP8B1 mRNA

NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898

G

cytohesin 3

increases expression

kojic acid results in increased expression of CYTH3 mRNA

NCBI chr 7:6,161,779...6,272,624
Ensembl chr 7:6,161,779...6,272,644

G

cytohesin 1 interacting protein

increases expression

kojic acid results in increased expression of CYTIP mRNA

NCBI chr 2:157,414,619...157,444,089
Ensembl chr 2:157,414,619...157,488,961

G

diacylglycerol lipase alpha

increases expression

kojic acid results in increased expression of DAGLA mRNA

NCBI chr11:61,680,391...61,747,001
Ensembl chr11:61,680,391...61,747,001

G

DAZ associated protein 2

increases expression

kojic acid results in increased expression of DAZAP2 mRNA

NCBI chr12:51,238,826...51,246,717
Ensembl chr12:51,238,724...51,271,362

G

DDB1 and CUL4 associated factor 13

decreases expression

kojic acid results in decreased expression of DCAF13 mRNA

NCBI chr 8:103,415,386...103,443,453
Ensembl chr 8:103,414,714...103,443,453

G

dopachrome tautomerase

decreases expression

kojic acid results in decreased expression of DCT protein

NCBI chr13:94,436,811...94,549,406
Ensembl chr13:94,436,811...94,479,682

G

DNA damage inducible transcript 3

multiple interactions

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DDIT3 mRNA

NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737

G

DEK proto-oncogene

decreases expression

kojic acid results in decreased expression of DEK mRNA

NCBI chr 6:18,223,860...18,264,530
Ensembl chr 6:18,223,860...18,264,548

G

DLG associated protein 4

increases expression

kojic acid results in increased expression of DLGAP4 mRNA

NCBI chr20:36,306,339...36,528,633
Ensembl chr20:36,306,336...36,528,637

G

distal-less homeobox 1

decreases expression

kojic acid results in decreased expression of DLX1 mRNA

NCBI chr 2:172,085,507...172,089,674
Ensembl chr 2:172,084,740...172,089,677

G

Dmx like 1

decreases expression

kojic acid results in decreased expression of DMXL1 mRNA

NCBI chr 5:119,071,027...119,249,127
Ensembl chr 5:119,037,772...119,249,138

G

DnaJ heat shock protein family (Hsp40) member A1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DNAJA1 mRNA

NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907

G

DnaJ heat shock protein family (Hsp40) member A2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of DNAJA2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of DNAJA2 mRNA

NCBI chr16:46,955,362...46,973,674
Ensembl chr16:46,955,362...46,973,674

G

deoxynucleotidyltransferase terminal interacting protein 2

decreases expression

kojic acid results in decreased expression of DNTTIP2 mRNA

NCBI chr 1:93,866,284...93,879,206
Ensembl chr 1:93,866,284...93,879,918

G

dedicator of cytokinesis 4

increases expression

kojic acid results in increased expression of DOCK4 mRNA

NCBI chr 7:111,726,110...112,206,399
Ensembl chr 7:111,726,110...112,206,407

G

docking protein 4

decreases expression

kojic acid results in decreased expression of DOK4 mRNA

NCBI chr16:57,471,922...57,487,322
Ensembl chr16:57,471,922...57,487,327

G

dihydropyrimidine dehydrogenase

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of DPYD mRNA

NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000

G

dentin sialophosphoprotein

decreases expression

kojic acid results in decreased expression of DSPP mRNA

NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873

G

destrin, actin depolymerizing factor

increases expression

kojic acid results in increased expression of DSTN mRNA

NCBI chr20:17,570,075...17,609,919
Ensembl chr20:17,570,075...17,609,919

G

dynein light chain Tctex-type 3

decreases expression

kojic acid results in decreased expression of DYNLT3 mRNA

NCBI chr X:37,838,836...37,847,571
Ensembl chr X:37,836,757...37,847,571

G

E2F transcription factor 3

increases expression

kojic acid results in increased expression of E2F3 mRNA

NCBI chr 6:20,401,879...20,493,714
Ensembl chr 6:20,401,879...20,493,714

G

E2F transcription factor 8

increases expression

kojic acid results in increased expression of E2F8 mRNA

NCBI chr11:19,224,063...19,241,655
Ensembl chr11:19,224,063...19,241,620

G

ephrin A3

decreases expression

kojic acid results in decreased expression of EFNA3 mRNA

NCBI chr 1:155,078,837...155,087,538
Ensembl chr 1:155,078,837...155,087,538

G

early growth response 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of EGR1 mRNA

NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303

G

eukaryotic translation initiation factor 4E

decreases expression

kojic acid results in decreased expression of EIF4E mRNA

NCBI chr 4:98,879,276...98,929,133
Ensembl chr 4:98,879,276...98,929,133

G

eukaryotic translation initiation factor 5A2

increases expression

kojic acid results in increased expression of EIF5A2 mRNA

NCBI chr 3:170,888,418...170,908,637
Ensembl chr 3:170,888,418...170,908,644

G

elastase, neutrophil expressed

decreases expression

kojic acid results in decreased expression of ELANE mRNA

NCBI chr19:852,303...856,243
Ensembl chr19:851,014...856,247

G

E1A binding protein p300

increases expression

kojic acid results in increased expression of EP300 mRNA

NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077

G

EPH receptor A10

decreases expression

kojic acid results in decreased expression of EPHA10 mRNA

NCBI chr 1:37,713,880...37,765,120
Ensembl chr 1:37,713,880...37,765,133

G

EPH receptor A4

increases expression

kojic acid results in increased expression of EPHA4 mRNA

NCBI chr 2:221,418,027...221,574,202
Ensembl chr 2:221,418,027...221,574,202

G

epoxide hydrolase 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX1 mRNA

NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563

G

epoxide hydrolase 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX2 mRNA

NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564

G

ERCC excision repair 2, TFIIH core complex helicase subunit

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC2 mRNA

NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918

G

ERCC excision repair 3, TFIIH core complex helicase subunit

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of ERCC3 mRNA

NCBI chr 2:127,257,290...127,294,144
Ensembl chr 2:127,257,290...127,294,166

G

ERCC excision repair 4, endonuclease catalytic subunit

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC4 mRNA

NCBI chr16:13,920,154...13,952,348
Ensembl chr16:13,920,138...13,952,348

G

ERCC excision repair 5, endonuclease

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of ERCC5 mRNA

NCBI chr13:102,846,032...102,875,995
Ensembl chr13:102,845,831...102,875,995

G

endothelial cell adhesion molecule

increases expression

kojic acid results in increased expression of ESAM mRNA

NCBI chr11:124,753,126...124,762,290
Ensembl chr11:124,752,583...124,762,290

G

epithelial splicing regulatory protein 1

increases expression

kojic acid results in increased expression of ESRP1 mRNA

NCBI chr 8:94,641,174...94,707,466
Ensembl chr 8:94,641,074...94,707,466

G

exonuclease 3'-5' domain containing 1

decreases expression

kojic acid results in decreased expression of EXD1 mRNA

NCBI chr15:41,182,728...41,230,757
Ensembl chr15:41,182,725...41,230,757

G

exocyst complex component 2

increases expression

kojic acid results in increased expression of EXOC2 mRNA

NCBI chr 6:485,154...693,139
Ensembl chr 6:485,154...693,139

G

coagulation factor X

increases expression

kojic acid results in increased expression of F10 mRNA

NCBI chr13:113,122,799...113,149,529
Ensembl chr13:113,122,799...113,149,529

G

family with sequence similarity 241 member A

increases expression

kojic acid results in increased expression of FAM241A mRNA

NCBI chr 4:112,145,454...112,195,256
Ensembl chr 4:112,145,454...112,195,256

G

fibrillin 2

increases expression

kojic acid results in increased expression of FBN2 mRNA

NCBI chr 5:128,257,909...128,538,245
Ensembl chr 5:128,257,909...128,659,185

G

F-box protein 16

increases expression

kojic acid results in increased expression of FBXO16 mRNA

NCBI chr 8:28,428,412...28,490,229
Ensembl chr 8:28,348,287...28,490,278

G

FERRY endosomal RAB5 effector complex subunit 3

decreases expression

kojic acid results in decreased expression of FERRY3 mRNA

NCBI chr12:4,487,735...4,538,469
Ensembl chr12:4,487,735...4,538,508

G

fibroblast growth factor 12

increases expression

kojic acid results in increased expression of FGF12 mRNA

NCBI chr 3:192,139,390...192,727,541
Ensembl chr 3:192,139,390...192,767,764

G

fibroblast growth factor 5

decreases expression

kojic acid results in decreased expression of FGF5 mRNA

NCBI chr 4:80,266,588...80,291,017
Ensembl chr 4:80,266,639...80,336,680

G

fibroblast growth factor receptor 3

decreases expression

kojic acid results in decreased expression of FGFR3 mRNA

NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872

G

fibrinogen C domain containing 1

decreases expression

kojic acid results in decreased expression of FIBCD1 mRNA

NCBI chr 9:130,902,440...130,940,709
Ensembl chr 9:130,902,438...130,939,286

G

FKBP prolyl isomerase 10

increases expression

kojic acid results in increased expression of FKBP10 mRNA

NCBI chr17:41,813,004...41,823,213
Ensembl chr17:41,812,680...41,823,213

G

flavin containing dimethylaniline monoxygenase 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of FMO1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of FMO1 mRNA

NCBI chr 1:171,248,494...171,285,978
Ensembl chr 1:171,248,471...171,285,978

G

fucose-1-phosphate guanylyltransferase

decreases expression

kojic acid results in decreased expression of FPGT mRNA

NCBI chr 1:74,198,242...74,208,702
Ensembl chr 1:74,198,238...74,234,086

G

FERM and PDZ domain containing 4

decreases expression

kojic acid results in decreased expression of FRMPD4 mRNA

NCBI chr X:11,822,439...12,724,523
Ensembl chr X:11,822,423...12,724,523

G

ferritin heavy chain 1

increases expression

kojic acid results in increased expression of FTH1 mRNA; kojic acid results in increased expression of FTH1 protein

NCBI chr11:61,964,285...61,967,634
Ensembl chr11:61,959,718...61,967,634

G

frizzled class receptor 8

increases expression

kojic acid results in increased expression of FZD8 mRNA

NCBI chr10:35,638,247...35,642,296
Ensembl chr10:35,638,247...35,642,296

G

growth arrest and DNA damage inducible beta

multiple interactions

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GADD45B mRNA

NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,259

G

polypeptide N-acetylgalactosaminyltransferase 1

decreases expression

kojic acid results in decreased expression of GALNT1 mRNA

NCBI chr18:35,580,922...35,711,834
Ensembl chr18:35,581,117...35,711,834

G

Gfo/Idh/MocA-like oxidoreductase domain containing 1

decreases expression

kojic acid results in decreased expression of GFOD1 mRNA

NCBI chr 6:13,357,830...13,487,600
Ensembl chr 6:13,357,830...13,487,662

G

GLE1 RNA export mediator

decreases expression

kojic acid results in decreased expression of GLE1 mRNA

NCBI chr 9:128,504,692...128,542,288
Ensembl chr 9:128,504,655...128,543,874

G

guanosine monophosphate reductase

decreases expression

kojic acid results in decreased expression of GMPR mRNA

NCBI chr 6:16,238,587...16,295,549
Ensembl chr 6:16,238,587...16,295,549

G

G protein subunit beta 1

increases expression

kojic acid results in increased expression of GNB1 mRNA

NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,892,292

G

G protein-coupled receptor 146

decreases expression

kojic acid results in decreased expression of GPR146 mRNA

NCBI chr 7:1,044,546...1,059,261
Ensembl chr 7:1,044,546...1,059,261

G

G protein-coupled receptor 26

decreases expression

kojic acid results in decreased expression of GPR26 mRNA

NCBI chr10:123,666,355...123,697,399
Ensembl chr10:123,666,355...123,697,399

G

G protein-coupled receptor 32

increases expression

kojic acid results in increased expression of GPR32 mRNA

NCBI chr19:50,770,464...50,771,732
Ensembl chr19:50,770,464...50,771,732

G

G protein-coupled receptor 61

decreases expression

kojic acid results in decreased expression of GPR61 mRNA

NCBI chr 1:109,539,872...109,547,260
Ensembl chr 1:109,539,872...109,548,406

G

glutathione peroxidase 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GPX1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GPX1 mRNA

NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605

G

gasdermin A

decreases expression

kojic acid results in decreased expression of GSDMA mRNA

NCBI chr17:39,963,004...39,977,768
Ensembl chr17:39,953,263...39,977,768

G

glutathione-disulfide reductase

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of GSR mRNA

NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846

G

glutathione S-transferase alpha 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTA2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTA2 mRNA

NCBI chr 6:52,750,087...52,763,475
Ensembl chr 6:52,750,087...52,763,475

G

glutathione S-transferase alpha 4

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTA4 mRNA

NCBI chr 6:52,977,953...52,995,284
Ensembl chr 6:52,977,948...52,995,304

G

glutathione S-transferase mu 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM1 mRNA

NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039

G

glutathione S-transferase mu 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM2 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM2 mRNA

NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551

G

glutathione S-transferase mu 3

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of GSTM3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of GSTM3 mRNA

PMID:17917374 PMID:18544905

NCBI chr 1:109,733,937...109,741,038
Ensembl chr 1:109,733,932...109,741,038

G

guanylate cyclase 1 soluble subunit alpha 2

decreases expression

kojic acid results in decreased expression of GUCY1A2 mRNA

NCBI chr11:106,674,019...107,018,476
Ensembl chr11:106,674,019...107,018,476

G

H1.1 linker histone, cluster member

increases expression

kojic acid results in increased expression of H1-1 mRNA

NCBI chr 6:26,017,032...26,017,787
Ensembl chr 6:26,017,032...26,017,787

G

H2A clustered histone 14

increases expression

kojic acid results in increased expression of H2AC14 mRNA

NCBI chr 6:27,814,302...27,814,777
Ensembl chr 6:27,814,302...27,814,777

G

H2A clustered histone 6

increases expression

kojic acid results in increased expression of H2AC6 mRNA

NCBI chr 6:26,124,172...26,124,690
Ensembl chr 6:26,124,145...26,139,116

G

heart and neural crest derivatives expressed 1

increases expression

kojic acid results in increased expression of HAND1 mRNA

NCBI chr 5:154,474,972...154,478,227
Ensembl chr 5:154,474,972...154,478,227

G

harbinger transposase derived 1

decreases expression

kojic acid results in decreased expression of HARBI1 mRNA

NCBI chr11:46,602,861...46,617,895
Ensembl chr11:46,602,861...46,617,909

G

3-hydroxyisobutyryl-CoA hydrolase

decreases expression

kojic acid results in decreased expression of HIBCH mRNA

NCBI chr 2:190,189,735...190,319,826
Ensembl chr 2:190,189,735...190,344,193

G

histidine triad nucleotide binding protein 3

increases expression

kojic acid results in increased expression of HINT3 mRNA

NCBI chr 6:125,956,770...125,980,244
Ensembl chr 6:125,956,770...125,980,244

G

huntingtin interacting protein 1

increases expression

kojic acid results in increased expression of HIP1 mRNA

NCBI chr 7:75,533,298...75,738,941
Ensembl chr 7:75,533,298...75,738,962

G

HLF transcription factor, PAR bZIP family member

decreases expression

kojic acid results in decreased expression of HLF mRNA

NCBI chr17:55,264,960...55,325,187
Ensembl chr17:55,264,960...55,325,187

G

hyaluronan mediated motility receptor

decreases expression

kojic acid results in decreased expression of HMMR mRNA

NCBI chr 5:163,460,632...163,491,941
Ensembl chr 5:163,460,203...163,491,941

G

heme oxygenase 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HMOX2 mRNA

NCBI chr16:4,474,736...4,510,347
Ensembl chr16:4,474,690...4,510,347

G

heterogeneous nuclear ribonucleoprotein H2

increases expression

kojic acid results in increased expression of HNRNPH2 mRNA

NCBI chr X:101,408,222...101,414,133
Ensembl chr X:101,408,222...101,414,133

G

HPS3 biogenesis of lysosomal organelles complex 2 subunit 1

decreases expression

kojic acid results in decreased expression of HPS3 mRNA

NCBI chr 3:149,129,638...149,173,732
Ensembl chr 3:149,129,638...149,173,732

G

heat shock protein 90 alpha family class A member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSP90AA1 mRNA

NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699

G

heat shock protein 90 alpha family class B member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSP90AB1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of HSP90AB1 mRNA

NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888

G

heat shock protein family A (Hsp70) member 1A

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPA1A mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of HSPA1A mRNA

NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946

G

heat shock protein family A (Hsp70) member 5

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPA5 mRNA

NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382

G

heat shock protein family B (small) member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPB1 mRNA

NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295

G

heat shock protein family D (Hsp60) member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPD1 mRNA

NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737

G

heat shock protein family E (Hsp10) member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HSPE1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of HSPE1 mRNA

PMID:17917374 PMID:18544905

NCBI chr 2:197,500,379...197,503,449
Ensembl chr 2:197,500,140...197,503,449

G

hypoxia up-regulated 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of HYOU1 mRNA

NCBI chr11:119,044,188...119,057,205
Ensembl chr11:119,044,188...119,057,227

G

insulin like growth factor 2 receptor

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of IGF2R mRNA

NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507

G

interleukin 1 alpha

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of IL1A mRNA

NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493

G

interleukin 1 beta

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of IL1B mRNA

NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816

G

interleukin 1 receptor like 1

increases expression

kojic acid results in increased expression of IL1RL1 mRNA

NCBI chr 2:102,311,563...102,352,356
Ensembl chr 2:102,311,502...102,352,037

G

interleukin 22 receptor subunit alpha 1

increases expression

kojic acid results in increased expression of IL22RA1 mRNA

NCBI chr 1:24,119,771...24,143,140
Ensembl chr 1:24,119,771...24,143,140

G

interleukin 6

decreases expression

kojic acid results in decreased expression of IL6 protein

NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002

G

interleukin 6 cytokine family signal transducer

decreases expression

kojic acid results in decreased expression of IL6ST mRNA

NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022

G

inner centromere protein

increases expression

kojic acid results in increased expression of INCENP mRNA

NCBI chr11:62,124,011...62,153,169
Ensembl chr11:62,123,998...62,153,169

G

Jun proto-oncogene, AP-1 transcription factor subunit

increases expression

kojic acid results in increased expression of JUN mRNA

NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048

G

lysyl-tRNA synthetase 1

decreases expression

kojic acid results in decreased expression of KARS1 mRNA

NCBI chr16:75,627,724...75,647,665
Ensembl chr16:75,627,474...75,648,643

G

potassium voltage-gated channel subfamily A regulatory beta subunit 3

decreases expression

kojic acid results in decreased expression of KCNAB3 mRNA

NCBI chr17:7,921,859...7,929,856
Ensembl chr17:7,921,859...7,929,856

G

potassium channel tetramerization domain containing 17

decreases expression

kojic acid results in decreased expression of KCTD17 mRNA

NCBI chr22:37,051,742...37,063,390
Ensembl chr22:37,051,739...37,063,390

G

lysine demethylase 4D

increases expression

kojic acid results in increased expression of KDM4D mRNA

NCBI chr11:94,973,709...94,999,519
Ensembl chr11:94,973,709...94,999,519

G

KLF transcription factor 5

increases expression

kojic acid results in increased expression of KLF5 mRNA

NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541

G

kelch like family member 13

increases expression

kojic acid results in increased expression of KLHL13 mRNA

NCBI chr X:117,897,813...118,117,340
Ensembl chr X:117,897,813...118,117,340

G

kallikrein B1

decreases expression

kojic acid results in decreased expression of KLKB1 mRNA

NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471

G

keratin 7

increases expression

kojic acid results in increased expression of KRT7 mRNA

NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186

G

kinectin 1

decreases expression

kojic acid results in decreased expression of KTN1 mRNA

NCBI chr14:55,580,207...55,684,584
Ensembl chr14:55,559,072...55,701,526

G

La ribonucleoprotein 7, transcriptional regulator

decreases expression

kojic acid results in decreased expression of LARP7 mRNA

NCBI chr 4:112,637,143...112,657,586
Ensembl chr 4:112,637,077...112,657,696

G

leukocyte immunoglobulin like receptor B5

decreases expression

kojic acid results in decreased expression of LILRB5 mRNA

NCBI chr19:54,249,421...54,257,273
Ensembl chr19:54,249,421...54,257,301

G

LDL receptor related protein 6

decreases expression

kojic acid results in decreased expression of LRP6 mRNA

NCBI chr12:12,116,025...12,267,044
Ensembl chr12:12,116,025...12,267,044

G

leucine rich repeat containing 4

decreases expression

kojic acid results in decreased expression of LRRC4 mRNA

NCBI chr 7:128,027,071...128,032,128
Ensembl chr 7:128,027,071...128,032,107

G

leucine rich repeat containing 9

increases expression

kojic acid results in increased expression of LRRC9 mRNA

NCBI chr14:59,919,713...60,066,817
Ensembl chr14:59,919,713...60,066,817

G

macrophage erythroblast attacher, E3 ubiquitin ligase

increases expression

kojic acid results in increased expression of MAEA mRNA

NCBI chr 4:1,289,891...1,340,137
Ensembl chr 4:1,289,887...1,340,147

G

MAF bZIP transcription factor K

decreases expression

kojic acid results in decreased expression of MAFK mRNA

NCBI chr 7:1,530,702...1,543,043
Ensembl chr 7:1,530,702...1,543,043

G

MAGE family member C2

increases expression

kojic acid results in increased expression of MAGEC2 mRNA

NCBI chr X:142,202,342...142,205,290
Ensembl chr X:142,202,342...142,205,290

G

MAGE family member F1

increases expression

kojic acid results in increased expression of MAGEF1 mRNA

NCBI chr 3:184,710,364...184,712,064
Ensembl chr 3:184,710,364...184,712,064

G

monoamine oxidase A

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MAOA mRNA

NCBI chr X:43,655,006...43,746,817
Ensembl chr X:43,654,907...43,746,817

G

monoamine oxidase B

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MAOB mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MAOB mRNA

NCBI chr X:43,766,610...43,882,450
Ensembl chr X:43,766,610...43,882,450

G

MAP7 domain containing 2

decreases expression

kojic acid results in decreased expression of MAP7D2 mRNA

NCBI chr X:20,006,713...20,116,907
Ensembl chr X:20,006,713...20,116,907

G

mitogen-activated protein kinase 1

decreases phosphorylation

kojic acid results in decreased phosphorylation of MAPK1 protein

NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680

G

mitogen-activated protein kinase 3

decreases phosphorylation

kojic acid results in decreased phosphorylation of MAPK3 protein

NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506

G

mitogen-activated protein kinase 8

decreases expression

kojic acid results in decreased expression of MAPK8 mRNA

NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360

G

muscleblind like splicing regulator 1

decreases expression

kojic acid results in decreased expression of MBNL1 mRNA

NCBI chr 3:152,243,632...152,465,780
Ensembl chr 3:152,243,828...152,465,780

G

melanocortin 1 receptor

decreases expression
increases expression

kojic acid results in decreased expression of MC1R protein
kojic acid results in increased expression of MC1R protein

PMID:23738040 PMID:27586645

NCBI chr16:89,918,862...89,920,972
Ensembl chr16:89,912,119...89,920,973

G

MyoD family inhibitor

decreases expression

kojic acid results in decreased expression of MDFI mRNA

NCBI chr 6:41,637,018...41,654,244
Ensembl chr 6:41,636,882...41,654,244

G

MDM2 proto-oncogene

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MDM2 mRNA

NCBI chr12:68,808,172...68,850,686
Ensembl chr12:68,808,177...68,845,544

G

malic enzyme 3

decreases expression

kojic acid results in decreased expression of ME3 mRNA

NCBI chr11:86,434,930...86,672,616
Ensembl chr11:86,441,108...86,672,636

G

mediator complex subunit 14

increases expression

kojic acid results in increased expression of MED14 mRNA

NCBI chr X:40,648,305...40,736,159
Ensembl chr X:40,648,305...40,735,858

G

mex-3 RNA binding family member B

increases expression

kojic acid results in increased expression of MEX3B mRNA

NCBI chr15:82,041,778...82,046,018
Ensembl chr15:82,041,778...82,046,119

G

microfibril associated protein 4

decreases expression

kojic acid results in decreased expression of MFAP4 mRNA

NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190

G

O-6-methylguanine-DNA methyltransferase

multiple interactions

[kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA; Ascorbic Acid inhibits the reaction [[kojic acid co-treated with Diethylnitrosamine] results in increased expression of MGMT mRNA]

NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983

G

microsomal glutathione S-transferase 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MGST1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MGST1 mRNA

NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259

G

midnolin

decreases expression

kojic acid results in decreased expression of MIDN mRNA

NCBI chr19:1,248,583...1,259,143
Ensembl chr19:1,248,553...1,259,143

G

macrophage migration inhibitory factor

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MIF mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of MIF mRNA

NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227

G

meiotic nuclear divisions 1

increases expression

kojic acid results in increased expression of GAJ mRNA

NCBI chr 4:153,344,649...153,415,118
Ensembl chr 4:153,344,649...153,415,118

G

mitochondrial ribosomal protein L30

decreases expression

kojic acid results in decreased expression of MRPL30 mRNA

NCBI chr 2:99,181,184...99,199,561
Ensembl chr 2:99,181,152...99,199,561

G

mitochondrially encoded cytochrome c oxidase I

increases expression

kojic acid results in increased expression of COX1 mRNA; kojic acid results in increased expression of COX1 protein

NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445

G

Mtr4 exosome RNA helicase

decreases expression

kojic acid results in decreased expression of MTREX mRNA

NCBI chr 5:55,307,989...55,425,579
Ensembl chr 5:55,307,989...55,425,579

G

major vault protein

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of MVP mRNA

NCBI chr16:29,820,394...29,848,039
Ensembl chr16:29,820,394...29,848,039

G

N-alpha-acetyltransferase 25, NatB auxiliary subunit

increases expression

kojic acid results in increased expression of NAA25 mRNA

NCBI chr12:112,026,689...112,108,783
Ensembl chr12:112,026,689...112,108,796

G

neurocalcin delta

decreases expression

kojic acid results in decreased expression of NCALD mRNA

NCBI chr 8:101,686,542...102,124,907
Ensembl chr 8:101,686,542...102,124,907

G

NADH:ubiquinone oxidoreductase subunit A1

increases expression

kojic acid results in increased expression of NDUFA1 mRNA

NCBI chr X:119,871,832...119,876,662
Ensembl chr X:119,871,832...119,876,662

G

nectin cell adhesion molecule 4

increases expression

kojic acid results in increased expression of NECTIN4 mRNA

NCBI chr 1:161,070,998...161,089,558
Ensembl chr 1:161,070,998...161,089,558

G

nuclear factor, interleukin 3 regulated

increases expression

kojic acid results in increased expression of NFIL3 mRNA

NCBI chr 9:91,409,045...91,483,497
Ensembl chr 9:91,409,045...91,423,832

G

NFKB inhibitor alpha

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NFKBIA mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of NFKBIA mRNA

NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749

G

NFKB inhibitor epsilon

increases expression

kojic acid results in increased expression of NFKBIE mRNA

NCBI chr 6:44,258,166...44,265,551
Ensembl chr 6:44,258,166...44,265,788

G

NK6 homeobox 1

decreases expression

kojic acid results in decreased expression of NKX6-1 mRNA

NCBI chr 4:84,491,985...84,499,292
Ensembl chr 4:84,491,985...84,499,292

G

neuroligin 2

decreases expression

kojic acid results in decreased expression of NLGN2 mRNA

NCBI chr17:7,404,653...7,419,860
Ensembl chr17:7,404,874...7,419,860

G

NOC3 like DNA replication regulator

decreases expression

kojic acid results in decreased expression of NOC3L mRNA

NCBI chr10:94,314,907...94,362,939
Ensembl chr10:94,333,226...94,362,959

G

nucleolar protein 11

decreases expression

kojic acid results in decreased expression of NOL11 mRNA

NCBI chr17:67,717,936...67,744,531
Ensembl chr17:67,717,931...67,744,531

G

nuclear receptor subfamily 1 group I member 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NR1I2 mRNA

NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487

G

nuclear receptor subfamily 1 group I member 3

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of NR1I3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of NR1I3 mRNA

NCBI chr 1:161,229,669...161,238,203
Ensembl chr 1:161,229,666...161,238,244

G

nudix hydrolase 10

decreases expression

kojic acid results in decreased expression of NUDT10 mRNA

NCBI chr X:51,332,231...51,337,525
Ensembl chr X:51,332,231...51,337,525

G

outer dynein arm docking complex subunit 2

increases expression

kojic acid results in increased expression of ODAD2 mRNA

NCBI chr10:27,812,168...27,999,675
Ensembl chr10:27,775,186...27,999,079

G

olfactomedin like 1

decreases expression

kojic acid results in decreased expression of OLFML1 mRNA

NCBI chr11:7,485,506...7,511,377
Ensembl chr11:7,485,388...7,511,377

G

olfactory receptor family 51 subfamily B member 4

decreases expression

kojic acid results in decreased expression of OR51B4 mRNA

NCBI chr11:5,301,014...5,301,946
Ensembl chr11:5,301,014...5,301,946

G

oxysterol binding protein 2

decreases expression

kojic acid results in decreased expression of OSBP2 mRNA

NCBI chr22:30,693,782...30,907,813
Ensembl chr22:30,693,782...30,907,824

G

osteoclastogenesis associated transmembrane protein 1

decreases expression

kojic acid results in decreased expression of OSTM1 mRNA

NCBI chr 6:108,041,409...108,074,741
Ensembl chr 6:108,029,245...108,165,854

G

orthodenticle homeobox 1

increases expression

kojic acid results in increased expression of OTX1 mRNA

NCBI chr 2:63,049,735...63,057,831
Ensembl chr 2:63,050,057...63,057,836

G

PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1

increases expression

kojic acid results in increased expression of PABIR1 mRNA

NCBI chr 9:68,780,065...68,785,566
Ensembl chr 9:68,780,065...68,785,566

G

PAXIP1 associated glutamate rich protein 1

increases expression

kojic acid results in increased expression of PAGR1 mRNA

NCBI chr16:29,816,152...29,822,489
Ensembl chr16:29,816,152...29,822,489

G

phenylalanine hydroxylase

decreases expression

kojic acid results in decreased expression of PAH mRNA

NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410

G

poly(ADP-ribose) glycohydrolase

increases expression

kojic acid results in increased expression of PARG mRNA

NCBI chr10:49,818,279...49,942,027
Ensembl chr10:49,818,279...49,970,203

G

PDZ binding kinase

decreases expression

kojic acid results in decreased expression of PBK mRNA

NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082

G

proliferating cell nuclear antigen

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of PCNA protein
[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in increased expression of PCNA protein

PMID:17917374 PMID:18544905

NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626

G

pecanex 3

decreases expression

kojic acid results in decreased expression of PCNX3 mRNA

NCBI chr11:65,615,776...65,637,439
Ensembl chr11:65,615,776...65,637,439

G

proprotein convertase subtilisin/kexin type 4

decreases expression

kojic acid results in decreased expression of PCSK4 mRNA

NCBI chr19:1,481,428...1,490,876
Ensembl chr19:1,481,428...1,490,752

G

phosducin like

increases expression

kojic acid results in increased expression of PDCL mRNA

NCBI chr 9:122,818,097...122,828,588
Ensembl chr 9:122,798,389...122,828,588

G

pyruvate dehydrogenase E1 subunit alpha 1

increases expression

kojic acid results in increased expression of PDHA1 mRNA

NCBI chr X:19,343,927...19,361,718
Ensembl chr X:19,343,893...19,361,718

G

protein disulfide isomerase family A member 3

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PDIA3 mRNA

NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279

G

PDZ and LIM domain 2

increases expression

kojic acid results in increased expression of PDLIM2 mRNA

NCBI chr 8:22,578,741...22,598,026
Ensembl chr 8:22,578,279...22,598,025

G

PPARGC1 and ESRR induced regulator, muscle 1

decreases expression

kojic acid results in decreased expression of PERM1 mRNA

NCBI chr 1:975,198...982,093
Ensembl chr 1:975,198...982,117

G

peroxisomal biogenesis factor 5 like

decreases expression

kojic acid results in decreased expression of PEX5L mRNA

NCBI chr 3:179,794,958...180,036,937
Ensembl chr 3:179,794,958...180,037,053

G

phosphoglucomutase 2

increases expression

kojic acid results in increased expression of PGM2 mRNA

NCBI chr 4:37,826,686...37,862,937
Ensembl chr 4:37,826,660...37,862,937

G

phosphatidylinositol glycan anchor biosynthesis class Q

decreases expression

kojic acid results in decreased expression of PIGQ mRNA

NCBI chr16:569,968...584,109
Ensembl chr16:566,995...584,109

G

phosphatidylinositol transfer protein beta

increases expression

kojic acid results in increased expression of PITPNB mRNA

NCBI chr22:27,851,669...27,919,256
Ensembl chr22:27,851,669...27,920,134

G

PLAG1 like zinc finger 1

increases expression

kojic acid results in increased expression of PLAGL1 mRNA

NCBI chr 6:143,940,300...144,064,599
Ensembl chr 6:143,940,300...144,064,599

G

protein O-glucosyltransferase 2

increases expression

kojic acid results in increased expression of POGLUT2 mRNA

NCBI chr13:102,784,281...102,798,976
Ensembl chr13:102,784,281...102,799,040

G

paraoxonase 3

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PON3 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of PON3 mRNA

NCBI chr 7:95,359,872...95,396,375
Ensembl chr 7:95,359,872...95,396,375

G

cytochrome p450 oxidoreductase

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of POR mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of POR mRNA

NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855

G

POU class 2 homeobox 3

decreases expression

kojic acid results in decreased expression of POU2F3 mRNA

NCBI chr11:120,236,638...120,319,945
Ensembl chr11:120,236,640...120,319,945

G

protein phosphatase 4 regulatory subunit 1

increases expression

kojic acid results in increased expression of PPP4R1 mRNA

NCBI chr18:9,546,794...9,617,199
Ensembl chr18:9,546,791...9,615,240

G

peroxiredoxin 1

multiple interactions

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PRDX1 mRNA

NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732

G

peroxiredoxin 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of PRDX2 mRNA

NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800

G

proteoglycan 2, pro eosinophil major basic protein

decreases expression

kojic acid results in decreased expression of PRG2 mRNA

NCBI chr11:57,386,780...57,390,650
Ensembl chr11:57,386,780...57,390,650

G

prickle planar cell polarity protein 3

decreases expression

kojic acid results in decreased expression of PRICKLE3 mRNA

NCBI chr X:49,174,802...49,186,373
Ensembl chr X:49,174,802...49,186,528

G

DNA primase subunit 1

decreases expression

kojic acid results in decreased expression of PRIM1 mRNA

NCBI chr12:56,731,580...56,752,323
Ensembl chr12:56,730,438...56,752,374

G

protein arginine methyltransferase 2

decreases expression

kojic acid results in decreased expression of PRMT2 mRNA

NCBI chr21:46,635,674...46,665,124
Ensembl chr21:46,635,595...46,665,124

G

pre-mRNA processing factor 40 homolog A

decreases expression

kojic acid results in decreased expression of PRPF40A mRNA

NCBI chr 2:152,651,732...152,718,019
Ensembl chr 2:152,651,593...152,718,012

G

phosphoribosyl pyrophosphate synthetase 2

increases expression

kojic acid results in increased expression of PRPS2 mRNA

NCBI chr X:12,791,412...12,824,222
Ensembl chr X:12,791,355...12,824,222

G

proline rich 18

decreases expression

kojic acid results in decreased expression of PRR18 mRNA

NCBI chr 6:166,305,300...166,308,392
Ensembl chr 6:166,305,300...166,308,448

G

proline rich coiled-coil 2C

increases expression

kojic acid results in increased expression of PRRC2C mRNA

NCBI chr 1:171,485,530...171,593,511
Ensembl chr 1:171,485,530...171,593,511

G

paired related homeobox 1

decreases expression

kojic acid results in decreased expression of PRRX1 mRNA

NCBI chr 1:170,662,768...170,739,421
Ensembl chr 1:170,662,728...170,739,421

G

proteasome 26S subunit, ATPase 6

decreases expression

kojic acid results in decreased expression of PSMC6 mRNA

NCBI chr14:52,707,200...52,728,590
Ensembl chr14:52,707,178...52,728,590

G

proteasome 26S subunit, non-ATPase 3

decreases expression

kojic acid results in decreased expression of PSMD3 mRNA

NCBI chr17:39,980,807...39,997,959
Ensembl chr17:39,980,807...39,997,959

G

prothymosin alpha pseudogene 7

increases expression

kojic acid results in increased expression of PTMAP7 mRNA

NCBI chr14:92,026,422...92,027,567

G

pseudouridine synthase 7 like

decreases expression

kojic acid results in decreased expression of PUS7L mRNA

NCBI chr12:43,718,992...43,758,790
Ensembl chr12:43,718,992...43,758,793

G

RAB3 GTPase activating protein catalytic subunit 1

increases expression

kojic acid results in increased expression of RAB3GAP1 mRNA

NCBI chr 2:135,052,292...135,176,396
Ensembl chr 2:135,052,289...135,176,667

G

RAB6B, member RAS oncogene family

decreases expression

kojic acid results in decreased expression of RAB6B mRNA

NCBI chr 3:133,824,235...133,895,882
Ensembl chr 3:133,824,235...133,895,882

G

RAD1 checkpoint DNA exonuclease

increases expression

kojic acid results in increased expression of RAD1 mRNA

NCBI chr 5:34,905,260...34,915,504
Ensembl chr 5:34,905,260...34,918,989

G

RAD23 homolog A, nucleotide excision repair protein

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of RAD23A mRNA

NCBI chr19:12,945,862...12,953,642
Ensembl chr19:12,945,855...12,953,642

G

RAD50 double strand break repair protein

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of RAD50 mRNA

NCBI chr 5:132,556,977...132,646,349
Ensembl chr 5:132,556,019...132,646,349

G

retinoic acid receptor alpha

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of RARA mRNA

NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643

G

retinoic acid receptor beta

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of RARB mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of RARB mRNA

NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932

G

ras related dexamethasone induced 1

increases expression

kojic acid results in increased expression of RASD1 mRNA

NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,395

G

RasGEF domain family member 1B

decreases expression

kojic acid results in decreased expression of RASGEF1B mRNA

NCBI chr 4:81,426,393...81,471,907
Ensembl chr 4:81,426,393...82,044,244

G

Ras association domain family member 3

increases expression

kojic acid results in increased expression of RASSF3 mRNA

NCBI chr12:64,506,964...64,697,564
Ensembl chr12:64,507,001...64,697,564

G

RB1 inducible coiled-coil 1

decreases expression

kojic acid results in decreased expression of RB1CC1 mRNA

NCBI chr 8:52,622,458...52,714,435
Ensembl chr 8:52,622,458...52,745,843

G

RNA binding motif protein 38

decreases expression

kojic acid results in decreased expression of RBM38 mRNA

NCBI chr20:57,391,396...57,409,333
Ensembl chr20:57,391,396...57,409,333

G

RecQ like helicase

decreases expression

kojic acid results in decreased expression of RECQL mRNA

NCBI chr12:21,468,910...21,501,635
Ensembl chr12:21,468,910...21,501,669

G

regulating synaptic membrane exocytosis 2

decreases expression

kojic acid results in decreased expression of RIMS2 mRNA

NCBI chr 8:103,500,610...104,256,094
Ensembl chr 8:103,500,610...104,254,430

G

round spermatid basic protein 1

decreases expression

kojic acid results in decreased expression of RSBN1 mRNA

NCBI chr 1:113,761,832...113,812,476
Ensembl chr 1:113,761,832...113,812,476

G

serum amyloid A4, constitutive

decreases expression

kojic acid results in decreased expression of SAA4 mRNA

NCBI chr11:18,231,355...18,236,802
Ensembl chr11:18,231,355...18,236,802

G

scavenger receptor class B member 1

increases expression

kojic acid results in increased expression of SCARB1 mRNA

NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668

G

sodium voltage-gated channel alpha subunit 10

decreases expression

kojic acid results in decreased expression of SCN10A mRNA

NCBI chr 3:38,696,807...38,816,217
Ensembl chr 3:38,696,802...38,816,286

G

sterol carrier protein 2

decreases expression

kojic acid results in decreased expression of SCP2 mRNA

NCBI chr 1:52,927,276...53,051,698
Ensembl chr 1:52,927,276...53,051,698

G

syndecan 4

decreases expression

kojic acid results in decreased expression of SDC4 mRNA

NCBI chr20:45,325,288...45,348,424
Ensembl chr20:45,325,288...45,348,424

G

SEC24 homolog B, COPII coat complex component

increases expression

kojic acid results in increased expression of SEC24B mRNA

NCBI chr 4:109,433,815...109,540,896
Ensembl chr 4:109,433,772...109,540,896

G

SEC62 homolog, preprotein translocation factor

decreases expression

kojic acid results in decreased expression of SEC62 mRNA

NCBI chr 3:169,966,807...169,998,373
Ensembl chr 3:169,966,635...169,998,373

G

secreted and transmembrane 1

decreases expression

kojic acid results in decreased expression of SECTM1 mRNA

NCBI chr17:82,321,024...82,333,959
Ensembl chr17:82,321,024...82,334,074

G

septin 7

decreases expression

kojic acid results in decreased expression of SEPTIN7 mRNA

NCBI chr 7:35,800,986...35,915,763
Ensembl chr 7:35,800,932...35,907,110

G

serpin family A member 5

decreases expression

kojic acid results in decreased expression of SERPINA5 mRNA

NCBI chr14:94,581,426...94,593,118
Ensembl chr14:94,561,442...94,593,118

G

SHC binding and spindle associated 1

increases expression

kojic acid results in increased expression of SHCBP1 mRNA

NCBI chr16:46,578,591...46,621,379
Ensembl chr16:46,578,591...46,621,379

G

SIN3 transcription regulator family member B

decreases expression

kojic acid results in decreased expression of SIN3B mRNA

NCBI chr19:16,829,398...16,880,349
Ensembl chr19:16,829,398...16,880,353

G

solute carrier family 17 member 2

decreases expression

kojic acid results in decreased expression of SLC17A2 mRNA

NCBI chr 6:25,912,754...25,930,691
Ensembl chr 6:25,912,754...25,930,691

G

solute carrier family 25 member 2

decreases expression

kojic acid results in decreased expression of SLC25A2 mRNA

NCBI chr 5:141,302,635...141,304,049
Ensembl chr 5:141,302,635...141,304,049

G

solute carrier family 35 member G5

decreases expression

kojic acid results in decreased expression of SLC35G5 mRNA

NCBI chr 8:11,331,012...11,332,360
Ensembl chr 8:11,331,012...11,332,360

G

solute carrier family 38 member 4

decreases expression

kojic acid results in decreased expression of SLC38A4 mRNA

NCBI chr12:46,764,761...46,832,431
Ensembl chr12:46,764,761...46,832,408

G

structural maintenance of chromosomes 6

decreases expression

kojic acid results in decreased expression of SMC6 mRNA

NCBI chr 2:17,663,812...17,753,810
Ensembl chr 2:17,663,812...17,800,242

G

small integral membrane protein 8

decreases expression

kojic acid results in decreased expression of SMIM8 mRNA

NCBI chr 6:87,322,588...87,342,329
Ensembl chr 6:87,322,583...87,399,749

G

sorting nexin 10

decreases expression

kojic acid results in decreased expression of SNX10 mRNA

NCBI chr 7:26,291,862...26,374,383
Ensembl chr 7:26,291,862...26,374,383

G

sterol O-acyltransferase 2

increases expression

kojic acid results in increased expression of SOAT2 mRNA

NCBI chr12:53,103,486...53,124,535
Ensembl chr12:53,103,486...53,124,535

G

superoxide dismutase 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SOD1 mRNA

NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931

G

superoxide dismutase 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SOD2 mRNA

NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529

G

spermatogenesis associated 25

decreases expression

kojic acid results in decreased expression of SPATA25 mRNA

NCBI chr20:45,886,491...45,891,016
Ensembl chr20:45,886,491...45,887,622

G

speedy/RINGO cell cycle regulator family member E1

increases expression

kojic acid results in increased expression of SPDYE1 mRNA

NCBI chr 7:43,997,897...44,010,124
Ensembl chr 7:43,997,897...44,010,124

G

secreted phosphoprotein 1

increases expression

kojic acid results in increased expression of SPP1 mRNA

NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532

G

serine palmitoyltransferase long chain base subunit 1

increases expression

kojic acid results in increased expression of SPTLC1 mRNA

NCBI chr 9:92,031,147...92,115,413
Ensembl chr 9:92,000,087...92,115,413

G

serine and arginine rich splicing factor 2

increases expression

kojic acid results in increased expression of SRSF2 mRNA

NCBI chr17:76,734,115...76,737,411
Ensembl chr17:76,734,115...76,737,333

G

SSX family member 1

increases expression

kojic acid results in increased expression of SSX1 mRNA

NCBI chr X:48,255,392...48,267,444
Ensembl chr X:48,255,392...48,267,444

G

ST13 Hsp70 interacting protein

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of ST13 mRNA

NCBI chr22:40,824,535...40,856,639
Ensembl chr22:40,824,535...40,856,639

G

ST18 C2H2C-type zinc finger transcription factor

decreases expression

kojic acid results in decreased expression of ST18 mRNA

NCBI chr 8:52,110,838...52,409,879
Ensembl chr 8:52,110,838...52,460,959

G

StAR related lipid transfer domain containing 8

decreases expression

kojic acid results in decreased expression of STARD8 mRNA

NCBI chr X:68,647,666...68,725,836
Ensembl chr X:68,647,666...68,725,842

G

syntaxin 6

increases expression

kojic acid results in increased expression of STX6 mRNA

NCBI chr 1:180,972,725...181,022,870
Ensembl chr 1:180,972,712...181,023,121

G

sulfotransferase family 1A member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SULT1A1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of SULT1A1 mRNA

NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044

G

sulfotransferase family 1B member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SULT1B1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in increased expression of SULT1B1 mRNA

NCBI chr 4:69,721,167...69,760,620
Ensembl chr 4:69,721,167...69,787,961

G

sulfotransferase family 1C member 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SULT1C2 mRNA

NCBI chr 2:108,288,895...108,309,915
Ensembl chr 2:108,288,639...108,309,915

G

sulfotransferase family 1C member 3

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SULT1C1 mRNA

NCBI chr 2:108,239,968...108,265,351
Ensembl chr 2:108,239,968...108,265,351

G

sulfotransferase family 1E member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of SULT1E1 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SULT1E1 mRNA

PMID:17917374 PMID:18544905

NCBI chr 4:69,821,122...69,860,145
Ensembl chr 4:69,841,212...69,860,145

G

sulfotransferase family 4A member 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of SULT4A1 mRNA; [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of SULT4A1 mRNA

NCBI chr22:43,824,509...43,862,513
Ensembl chr22:43,824,509...43,862,513

G

SUZ12 polycomb repressive complex 2 subunit

decreases expression

kojic acid results in decreased expression of SUZ12 mRNA

NCBI chr17:31,937,007...32,001,038
Ensembl chr17:31,937,007...32,001,038

G

switching B cell complex subunit SWAP70

increases expression

kojic acid results in increased expression of SWAP70 mRNA

NCBI chr11:9,664,077...9,752,993
Ensembl chr11:9,664,077...9,752,993

G

SYF2 pre-mRNA splicing factor

decreases expression

kojic acid results in decreased expression of SYF2 mRNA

NCBI chr 1:25,222,276...25,232,502
Ensembl chr 1:25,222,276...25,232,502

G

symplekin scaffold protein

decreases expression

kojic acid results in decreased expression of SYMPK mRNA

NCBI chr19:45,815,410...45,863,147
Ensembl chr19:45,815,410...45,863,194

G

synaptotagmin binding cytoplasmic RNA interacting protein

increases expression

kojic acid results in increased expression of SYNCRIP mRNA

NCBI chr 6:85,607,784...85,643,870
Ensembl chr 6:85,607,779...85,644,063

G

TATA-box binding protein associated factor 15

decreases expression

kojic acid results in decreased expression of TAF15 mRNA

NCBI chr17:35,809,484...35,847,242
Ensembl chr17:35,809,482...35,864,615

G

TAL bHLH transcription factor 1, erythroid differentiation factor

decreases expression

kojic acid results in decreased expression of TAL1 mRNA

NCBI chr 1:47,216,290...47,232,335
Ensembl chr 1:47,216,290...47,232,225

G

thromboxane A synthase 1

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of TBXAS1 mRNA

NCBI chr 7:139,778,242...140,020,293
Ensembl chr 7:139,777,051...140,020,325

G

transcription factor 21

decreases expression

kojic acid results in decreased expression of TCF21 mRNA

NCBI chr 6:133,889,113...133,895,537
Ensembl chr 6:133,889,113...133,895,553

G

transcobalamin 1

decreases expression

kojic acid results in decreased expression of TCN1 mRNA

NCBI chr11:59,852,808...59,866,487
Ensembl chr11:59,852,800...59,866,489

G

terminal nucleotidyltransferase 4B

decreases expression

kojic acid results in decreased expression of TENT4B mRNA

NCBI chr16:50,152,911...50,235,310
Ensembl chr16:50,152,911...50,235,310

G

transforming growth factor beta 1

multiple interactions

[Ascorbic Acid co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TGFB1 mRNA

NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922

G

thyroid hormone receptor beta

decreases expression

kojic acid results in decreased expression of THRB mRNA

NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756

G

tyrosine kinase with immunoglobulin like and EGF like domains 1

decreases expression

kojic acid results in decreased expression of TIE mRNA

NCBI chr 1:43,300,982...43,323,108
Ensembl chr 1:43,300,982...43,323,108

G

TIR domain containing adaptor protein

decreases expression

kojic acid results in decreased expression of TIRAP mRNA

NCBI chr11:126,283,093...126,294,933
Ensembl chr11:126,282,497...126,298,845

G

transmembrane and coiled-coil domains 5A

increases expression

kojic acid results in increased expression of TMCO5 mRNA

NCBI chr15:37,934,640...38,040,865
Ensembl chr15:37,921,939...37,967,724

G

transmembrane protein 217

increases expression

kojic acid results in increased expression of TMEM217 mRNA

NCBI chr 6:37,212,181...37,258,144
Ensembl chr 6:37,212,180...37,258,155

G

transmembrane protein 59 like

decreases expression

kojic acid results in decreased expression of TMEM59L mRNA

NCBI chr19:18,612,870...18,621,039
Ensembl chr19:18,607,430...18,621,039

G

thioredoxin related transmembrane protein 1

decreases expression

kojic acid results in decreased expression of TMX1 mRNA

NCBI chr14:51,240,247...51,257,655
Ensembl chr14:51,240,162...51,257,655

G

tumor necrosis factor

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TNF mRNA

NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336

G

TNF alpha induced protein 8 like 1

decreases expression

kojic acid results in decreased expression of TNFAIP8L1 mRNA

NCBI chr19:4,639,516...4,655,568
Ensembl chr19:4,639,516...4,655,568

G

TNF superfamily member 10

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TNFSF10 mRNA

NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475

G

torsin family 4 member A

decreases expression

kojic acid results in decreased expression of TOR4A mRNA

NCBI chr 9:137,277,726...137,282,641
Ensembl chr 9:137,277,726...137,282,641

G

tumor protein p53

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TP53 mRNA
[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of TRP53 mRNA

PMID:17917374 PMID:18544905

NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538

G

tumor protein p53 binding protein 2

increases expression

kojic acid results in increased expression of TP53BP2 mRNA

NCBI chr 1:223,779,893...223,845,947
Ensembl chr 1:223,779,893...223,845,954

G

two pore segment channel 1

increases expression

kojic acid results in increased expression of TPCN1 mRNA

NCBI chr12:113,221,464...113,298,585
Ensembl chr12:113,221,050...113,298,585

G

tyrosylprotein sulfotransferase 2

multiple interactions

[Diethylnitrosamine co-treated with kojic acid] results in decreased expression of TPST2 mRNA

NCBI chr22:26,521,996...26,590,132
Ensembl chr22:26,521,996...26,596,717

G

TNFRSF1A associated via death domain

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of TRADD mRNA; [Diethylnitrosamine co-treated with kojic acid] results in decreased expression of TRADD mRNA

NCBI chr16:67,154,185...67,159,909
Ensembl chr16:67,154,185...67,159,909

G

translocation associated membrane protein 1

decreases expression

kojic acid results in decreased expression of TRAM1 mRNA

NCBI chr 8:70,573,218...70,608,416
Ensembl chr 8:70,573,218...70,608,416

G

translocation associated membrane protein 2

decreases expression

kojic acid results in decreased expression of TRAM2 mRNA

NCBI chr 6:52,497,408...52,577,060
Ensembl chr 6:52,497,408...52,577,060

G

triggering receptor expressed on myeloid cells 1

decreases expression

kojic acid results in decreased expression of TREM1 mRNA

NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682

G

tRNA methyltransferase 10C, mitochondrial RNase P subunit

decreases expression

kojic acid results in decreased expression of TRMT10C mRNA

NCBI chr 3:101,561,868...101,566,446
Ensembl chr 3:101,561,868...101,566,446

G

tetraspanin 8

increases expression

kojic acid results in increased expression of TSPAN8 mRNA

NCBI chr12:71,125,096...71,157,999
Ensembl chr12:71,125,085...71,441,898

G

tetratricopeptide repeat domain 9

increases expression

kojic acid results in increased expression of TTC9 mRNA

NCBI chr14:70,641,916...70,675,366
Ensembl chr14:70,641,916...70,675,366

G

TTK protein kinase

decreases expression

kojic acid results in decreased expression of TTK mRNA

NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527

G

TUB like protein 3

decreases expression

kojic acid results in decreased expression of TULP3 mRNA

NCBI chr12:2,890,891...2,941,138
Ensembl chr12:2,877,223...2,941,138

G

twinfilin actin binding protein 1

decreases expression

kojic acid results in decreased expression of TWF1 mRNA

NCBI chr12:43,793,723...43,806,317
Ensembl chr12:43,793,723...43,806,328

G

tyrosinase

decreases activity
increases expression

kojic acid results in decreased activity of TYR protein
kojic acid results in increased expression of TYR mRNA; kojic acid results in increased expression of TYR protein

PMID:23738040 PMID:27586645

NCBI chr11:89,177,875...89,295,759
Ensembl chr11:89,177,875...89,295,759

G

tyrosinase related protein 1

decreases expression

kojic acid results in decreased expression of TYRP1 protein

NCBI chr 9:12,693,385...12,710,285
Ensembl chr 9:12,685,439...12,710,285

G

ubiquitin conjugating enzyme E2 D4 (putative)

decreases expression

kojic acid results in decreased expression of UBE2D4 mRNA

NCBI chr 7:43,926,436...43,956,136
Ensembl chr 7:43,926,436...43,956,136

G

ubiquitin conjugating enzyme E2 E1

decreases expression

kojic acid results in decreased expression of UBE2E1 mRNA

NCBI chr 3:23,805,955...23,891,640
Ensembl chr 3:23,805,955...23,891,640

G

ubiquitin conjugating enzyme E2 M

decreases expression

kojic acid results in decreased expression of UBE2M mRNA

NCBI chr19:58,555,712...58,558,611
Ensembl chr19:58,555,712...58,558,954

G

ubiquitin protein ligase E3 component n-recognin 7

increases expression

kojic acid results in increased expression of UBR7 mRNA

NCBI chr14:93,207,256...93,229,215
Ensembl chr14:93,207,241...93,229,215

G

ubiquitin recognition factor in ER associated degradation 1

increases expression

kojic acid results in increased expression of UFD1 mRNA

NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202

G

UDP glucuronosyltransferase family 1 member A3

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of UGT1A2 mRNA

NCBI chr 2:233,729,042...233,773,300
Ensembl chr 2:233,729,042...233,773,300

G

UDP glucuronosyltransferase family 1 member A6

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of UGT1A6 mRNA

NCBI chr 2:233,691,702...233,773,300
Ensembl chr 2:233,691,607...233,773,300

G

unc-5 netrin receptor C

decreases expression

kojic acid results in decreased expression of UNC5C mRNA

NCBI chr 4:95,162,504...95,548,973
Ensembl chr 4:95,162,504...95,549,206

G

uracil DNA glycosylase

multiple interactions

[Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of UNG mRNA

NCBI chr12:109,097,597...109,110,992
Ensembl chr12:109,097,597...109,126,725

G

ubiquitin specific peptidase 1

decreases expression

kojic acid results in decreased expression of USP1 mRNA

NCBI chr 1:62,436,395...62,451,804
Ensembl chr 1:62,436,297...62,451,804

G

ubiquitin specific peptidase 44

decreases expression

kojic acid results in decreased expression of USP44 mRNA

NCBI chr12:95,516,560...95,551,681
Ensembl chr12:95,516,560...95,551,476

G

UTP11 small subunit processome component

increases expression

kojic acid results in increased expression of UTP11 mRNA

NCBI chr 1:38,012,734...38,024,820
Ensembl chr 1:38,009,258...38,024,820

G

Wnt family member 10A

decreases expression

kojic acid results in decreased expression of WNT10A mRNA

NCBI chr 2:218,874,116...218,893,928
Ensembl chr 2:218,880,852...218,899,581

G

YEATS domain containing 2

increases expression

kojic acid results in increased expression of YEATS2 mRNA

NCBI chr 3:183,697,797...183,812,624
Ensembl chr 3:183,697,797...183,812,624

G

zinc finger CCCH-type containing 15

decreases expression

kojic acid results in decreased expression of ZC3H15 mRNA

NCBI chr 2:186,486,260...186,509,361
Ensembl chr 2:186,486,253...186,509,361

G

zinc finger DHHC-type palmitoyltransferase 20

decreases expression

kojic acid results in decreased expression of ZDHHC20 mRNA

NCBI chr13:21,372,571...21,459,303
Ensembl chr13:21,348,784...21,459,370

G

zinc finger AN1-type containing 1

decreases expression

kojic acid results in decreased expression of ZFAND1 mRNA

NCBI chr 8:81,701,331...81,721,304
Ensembl chr 8:81,701,334...81,732,903

G

zinc finger with KRAB and SCAN domains 8

decreases expression

kojic acid results in decreased expression of ZKSCAN8 mRNA

NCBI chr 6:28,141,635...28,159,460
Ensembl chr 6:28,141,883...28,159,460

G

zinc finger MYND-type containing 15

decreases expression

kojic acid results in decreased expression of ZMYND15 mRNA

NCBI chr17:4,739,833...4,746,119
Ensembl chr17:4,739,833...4,746,119

G

zinc finger protein 146

decreases expression

kojic acid results in decreased expression of ZNF146 mRNA

NCBI chr19:36,214,723...36,238,768
Ensembl chr19:36,214,602...36,238,771

G

zinc finger protein 414

decreases expression

kojic acid results in decreased expression of ZNF414 mRNA

NCBI chr19:8,509,678...8,514,167
Ensembl chr19:8,509,678...8,514,167

G

zinc finger protein 438

increases expression

kojic acid results in increased expression of ZNF438 mRNA

NCBI chr10:30,844,632...31,032,411
Ensembl chr10:30,820,207...31,031,937

G

zinc finger protein 483

decreases expression

kojic acid results in decreased expression of ZNF483 mRNA

NCBI chr 9:111,525,179...111,578,136
Ensembl chr 9:111,525,159...111,577,844

G

zinc finger protein 497

decreases expression

kojic acid results in decreased expression of ZNF497 mRNA

NCBI chr19:58,354,357...58,362,751
Ensembl chr19:58,354,357...58,362,848

G

zona pellucida glycoprotein 2

decreases expression

kojic acid results in decreased expression of ZP2 mRNA

NCBI chr16:21,197,450...21,214,510
Ensembl chr16:21,197,450...21,214,510

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	26034
chemical entity	26024
molecular entity	25991
mancude ring	11703
organic mancude parent	11703
mancude organic heterocyclic parent	11703
mancude organic heteromonocyclic parent	6538
pyran	431
4H-pyran	431
4H-pyran-4-one	0
kojic acid	432
pyryliums +	0
Path 2
Term	Annotations
CHEBI ontology	26034
subatomic particle	26009
composite particle	26009
hadron	26020
baryon	26009
nucleon	26009
atomic nucleus	26009
atom	26009
main group element atom	25834
p-block element atom	25834
carbon group element atom	25434
carbon atom	25403
organic molecular entity	25392
organic molecule	25222
organic cyclic compound	24274
organic heterocyclic compound	22328
organic heteromonocyclic compound	19212
pyrans	1177
pyran	431
4H-pyran	431
4H-pyran-4-one	0
kojic acid	432
pyryliums +	0

paths to the root