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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:organic disulfide
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Accession:CHEBI:35489 term browser browse the term
Definition:Compounds of structure RSSR in which R and R' are organic groups.
Synonyms:exact_synonym: disulfides
 related_synonym: Formula=S2R2;   SMILES=[*]SS[*];   an organic disulfide;   organic disulfides


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2,2'-dithiodiethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 affects response to substance ISO TP53 protein affects the susceptibility to 2-hydroxyethyl disulfide CTD PMID:22926048 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 multiple interactions ISO [2-hydroxyethyl disulfide co-treated with Glucose deficiency] results in decreased activity of [XRCC5 protein binds to XRCC6 protein] CTD PMID:22926048 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Xrcc6 X-ray repair cross complementing 6 multiple interactions ISO [2-hydroxyethyl disulfide co-treated with Glucose deficiency] results in decreased activity of [XRCC5 protein binds to XRCC6 protein] CTD PMID:22926048 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762 		JBrowse link
4,4'-dipyridyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO 4,4'-dipyridyl disulfide inhibits the reaction [5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate) binds to KEAP1 protein]; 4,4'-dipyridyl disulfide promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]] CTD PMID:15865434 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase affects binding ISO 4,4'-dipyridyl disulfide binds to MGMT protein CTD PMID:12974631 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
aldrithiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity EXP 2,2'-dipyridyl disulfide results in increased activity of CASP3 protein CTD PMID:11331359 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases activity EXP 2,2'-dipyridyl disulfide results in increased activity of CASP9 protein CTD PMID:11331359 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP 2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK1 protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; phenyl-N-tert-butylnitrone inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:11331359 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP 2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:11331359 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nppa natriuretic peptide A multiple interactions
increases expression		 EXP polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased expression of NPPA protein] CTD PMID:25449040 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A multiple interactions
increases phosphorylation		 EXP polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of PPP1R12A protein] CTD PMID:25449040 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425 		JBrowse link
allyl methyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity		 ISO allyl methyl disulfide inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]
allyl methyl disulfide results in decreased activity of CYP3A4 protein		 CTD PMID:18385293 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO allyl methyl disulfide inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:26969520 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO allyl methyl disulfide inhibits the reaction [Acetaminophen results in increased expression of IL6 protein] CTD PMID:26969520 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C multiple interactions ISO allyl methyl disulfide inhibits the reaction [Acetaminophen results in increased expression of PTPRC protein] CTD PMID:26969520 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO allyl methyl disulfide inhibits the reaction [Acetaminophen results in increased expression of TNF protein] CTD PMID:26969520 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
chetomin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 multiple interactions ISO chetomin inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA]; chetomin inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein] CTD PMID:21926265 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression
multiple interactions		 ISO chetomin results in decreased expression of HIF1A mRNA
chetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]]; chetomin inhibits the reaction [HIF1A protein promotes the reaction [TNF protein results in decreased metabolism of Oxygen]]		 CTD PMID:19744167 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO chetomin inhibits the reaction [HIF1A protein promotes the reaction [TNF protein results in decreased metabolism of Oxygen]] CTD PMID:19744167 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO chetomin inhibits the reaction [aristolochic acid I results in increased expression of VEGFA protein]; chetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]] CTD PMID:19744167 PMID:21554934 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
cystamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:17708605 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] CTD PMID:17708605 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Tgm2 transglutaminase 2 multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 mRNA]; Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 protein] CTD PMID:17708605 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:17708605 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
diallyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO diallyl disulfide results in increased expression of ABCB1 mRNA CTD PMID:22397993 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases expression
increases expression		 ISO diallyl disulfide results in decreased expression of ABCC1 mRNA
diallyl disulfide results in increased expression of ABCC1 mRNA		 CTD PMID:22397993 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
affects expression		 ISO diallyl disulfide results in increased expression of ABCC3 mRNA
diallyl disulfide affects the expression of ABCC3 mRNA		 CTD PMID:22397993 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
decreases expression		 ISO diallyl disulfide results in increased expression of ABCC4 mRNA
diallyl disulfide results in decreased expression of ABCC4 mRNA		 CTD PMID:22397993 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression
increases expression		 ISO diallyl disulfide results in decreased expression of ABCC6 mRNA
diallyl disulfide results in increased expression of ABCC6 mRNA		 CTD PMID:22397993 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464 		JBrowse link
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide multiple interactions ISO diallyl disulfide inhibits the reaction [Ethanol results in decreased expression of ADH1 protein] CTD PMID:35526736 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO diallyl disulfide results in increased phosphorylation of AKT1 protein CTD PMID:23663050 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO diallyl disulfide inhibits the reaction [Ethanol results in decreased expression of ALDH2 protein] CTD PMID:35526736 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO diallyl disulfide results in increased expression of ATF3 protein CTD PMID:15897233 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO diallyl disulfide results in increased expression of BAX mRNA; diallyl disulfide results in increased expression of BAX protein CTD PMID:17647244 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP
ISO		 diallyl disulfide results in decreased expression of BCL2 protein
diallyl disulfide results in decreased expression of BCL2 mRNA; diallyl disulfide results in decreased expression of BCL2 protein		 CTD PMID:14522920 PMID:16052692 PMID:17647244 PMID:30677442 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression ISO diallyl disulfide results in decreased expression of BDNF protein CTD PMID:23732363 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO diallyl disulfide results in decreased expression of BIRC3 protein CTD PMID:17647244 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO diallyl disulfide results in decreased expression of BIRC5 protein CTD PMID:17647244 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein modified form]; diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of CASP1 protein]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of CASP1 protein modified form]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of CASP1 protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased cleavage of CASP1 protein] CTD PMID:34896185 PMID:35526736 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
multiple interactions		 ISO diallyl disulfide results in increased activity of CASP3 protein
diallyl disulfide results in increased cleavage of CASP3 protein
diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]		 CTD PMID:14522920 PMID:17647244 PMID:30677442 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 increases activity ISO diallyl disulfide results in increased activity of CASP4 protein CTD PMID:17647244 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage		 ISO diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP8 protein]
diallyl disulfide results in increased cleavage of CASP8 protein		 CTD PMID:30677442 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage
multiple interactions		 ISO diallyl disulfide results in increased activity of CASP9 protein
diallyl disulfide results in increased cleavage of CASP9 protein
diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP9 protein]		 CTD PMID:14522920 PMID:17647244 PMID:30677442 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cast calpastatin decreases expression ISO diallyl disulfide results in decreased expression of CAST mRNA; diallyl disulfide results in decreased expression of CAST protein CTD PMID:17647244 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:24293383 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 multiple interactions ISO diallyl disulfide promotes the reaction [NOS3 protein binds to CAV1 protein] CTD PMID:20229525 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of CCL2 mRNA] CTD PMID:34896185 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccnb1 cyclin B1 decreases expression
increases expression		 ISO diallyl disulfide results in decreased expression of CCNB1 protein
diallyl disulfide results in increased expression of CCNB1 protein		 CTD PMID:16691315 PMID:19202565 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnc cyclin C multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of CCNC mRNA CTD PMID:31077537 NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584 		JBrowse link
G Cdh1 cadherin 1 decreases expression ISO diallyl disulfide results in decreased expression of CDH1 mRNA; diallyl disulfide results in decreased expression of CDH1 protein CTD PMID:20600798 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdhr1 cadherin-related family member 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of CDHR1 mRNA CTD PMID:31077537 NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396 		JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO diallyl disulfide results in decreased expression of CDK1 protein CTD PMID:16691315 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408 		JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of CDKAL1 mRNA CTD PMID:31077537 NCBI chr17:34,718,680...34,769,614
NCBI chr17:34,852,238...35,271,276
Ensembl chr17:34,718,687...35,407,524 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of CDKN2B mRNA CTD PMID:31077537 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cldn2 claudin 2 decreases expression ISO diallyl disulfide results in decreased expression of CLDN2 mRNA; diallyl disulfide results in decreased expression of CLDN2 protein CTD PMID:20600798 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838 		JBrowse link
G Cldn3 claudin 3 decreases expression ISO diallyl disulfide results in decreased expression of CLDN3 mRNA; diallyl disulfide results in decreased expression of CLDN3 protein CTD PMID:20600798 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001 		JBrowse link
G Cldn4 claudin 4 decreases expression ISO diallyl disulfide results in decreased expression of CLDN4 mRNA; diallyl disulfide results in decreased expression of CLDN4 protein CTD PMID:20600798 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Cldn5 claudin 5 decreases expression ISO diallyl disulfide results in decreased expression of CLDN5 mRNA; diallyl disulfide results in decreased expression of CLDN5 protein CTD PMID:20600798 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A multiple interactions ISO diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of CPT1A protein]; diallyl disulfide inhibits the reaction [Ethanol results in decreased expression of CPT1A protein] CTD PMID:35526736 NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases expression ISO diallyl disulfide results in decreased expression of CREB1 protein modified form CTD PMID:23732363 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression
decreases phosphorylation		 ISO diallyl disulfide results in increased expression of CTNNB1 mRNA; diallyl disulfide results in increased expression of CTNNB1 protein
diallyl disulfide results in decreased phosphorylation of CTNNB1 protein		 CTD PMID:20600798 PMID:23663050 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity		 EXP
ISO		 diallyl disulfide results in increased expression of CYP1A1 protein
diallyl disulfide results in decreased activity of CYP1A1 protein		 CTD PMID:16000231 PMID:18339364 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP diallyl disulfide results in increased expression of CYP1A2 protein CTD PMID:16000231 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO diallyl disulfide results in increased expression of CYP2B1 mRNA; diallyl disulfide results in increased expression of CYP2B2 mRNA CTD PMID:17353348 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions
decreases activity		 ISO
EXP		 diallyl disulfide results in decreased expression of CYP2E1 protein
diallyl disulfide inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]
diallyl disulfide results in decreased activity of CYP2E1 protein
[diallyl disulfide results in decreased expression of CYP2E1 protein] which results in decreased metabolism of and results in decreased susceptibility to Trichloroethylene; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein]		 CTD PMID:10774820 PMID:16000231 PMID:18339364 PMID:19325051 PMID:24293383 More... NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP diallyl disulfide results in increased expression of CYP3A2 protein CTD PMID:16000231 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dbr1 debranching RNA lariats 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of DBR1 mRNA CTD PMID:31077537 NCBI chr 8:100,139,039...100,150,768
Ensembl chr 8:100,139,034...100,151,030 		JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein decreases localization ISO diallyl disulfide results in decreased localization of DIABLO protein CTD PMID:17647244 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387 		JBrowse link
G Dus2 dihydrouridine synthase 2 decreases expression
multiple interactions		 EXP diallyl disulfide results in decreased expression of DUS2 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of DUS2 mRNA		 CTD PMID:31077537 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709 		JBrowse link
G Exo1 exonuclease 1 increases expression
multiple interactions		 EXP diallyl disulfide results in increased expression of EXO1 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of EXO1 mRNA		 CTD PMID:31077537 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654 		JBrowse link
G Fasn fatty acid synthase multiple interactions ISO diallyl disulfide inhibits the reaction [Ethanol results in decreased expression of FASN protein] CTD PMID:35526736 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of FOSL1 mRNA CTD PMID:31077537 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
increases expression		 EXP
ISO		 diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA]
diallyl disulfide results in increased expression of GCLC mRNA; diallyl disulfide results in increased expression of GCLC protein
[diallyl disulfide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of GCLC protein; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of GCLC mRNA]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of GCLC protein]; NFE2L2 protein affects the reaction [diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of GCLC mRNA]]		 CTD PMID:24293383 PMID:34896185 PMID:35526736 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit multiple interactions
increases expression		 ISO diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of GCLM mRNA]; NFE2L2 protein affects the reaction [diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of GCLM mRNA]]
diallyl disulfide results in increased expression of GCLM mRNA		 CTD PMID:34896185 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions		 ISO diallyl disulfide results in increased expression of GDF15 protein
TP53 protein affects the reaction [diallyl disulfide results in increased expression of GDF15 protein]		 CTD PMID:11925476 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP
ISO		 diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein]
diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of GPT protein]		 CTD PMID:24293383 PMID:34896185 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Grb2 growth factor receptor bound protein 2 affects expression
decreases expression		 ISO diallyl disulfide affects the expression of GRB2 protein
diallyl disulfide results in decreased expression of GRB2 protein		 CTD PMID:21695758 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Grhl1 grainyhead-like transcription factor 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of GRHL1 mRNA CTD PMID:31077537 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO diallyl disulfide results in increased phosphorylation of GSK3B protein CTD PMID:23663050 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased activity of GSR protein] CTD PMID:24293383 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of HES1 mRNA CTD PMID:31077537 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression		 EXP
ISO		 [Carbon Tetrachloride co-treated with diallyl disulfide] results in increased expression of HMOX1 protein; diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA]
diallyl disulfide results in increased expression of HMOX1 mRNA; diallyl disulfide results in increased expression of HMOX1 protein
[diallyl disulfide co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of HMOX1 protein; diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]; NFE2L2 protein affects the reaction [diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]]		 CTD PMID:24293383 PMID:34896185 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression
multiple interactions		 EXP diallyl disulfide results in increased expression of HSPA1A mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of HSPA1A mRNA		 CTD PMID:31077537 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions
decreases expression		 EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of HSPH1 mRNA
diallyl disulfide results in decreased expression of HSPH1 mRNA		 CTD PMID:31077537 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Id1 inhibitor of DNA binding 1 multiple interactions
increases expression		 EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of ID1 mRNA
diallyl disulfide results in increased expression of ID1 mRNA		 CTD PMID:31077537 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression
multiple interactions		 EXP diallyl disulfide results in increased expression of ID2 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of ID2 mRNA		 CTD PMID:31077537 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Id3 inhibitor of DNA binding 3 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of ID3 mRNA CTD PMID:31077537 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of IL1B protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL1B protein] CTD PMID:34896185 PMID:35526736 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA] CTD PMID:34896185 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of ITGB1BP1 mRNA CTD PMID:31077537 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO diallyl disulfide results in increased phosphorylation of JUN protein CTD PMID:14522920 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions		 ISO diallyl disulfide results in decreased expression of KEAP1 protein
diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of KEAP1 protein]		 CTD PMID:34896185 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression ISO diallyl disulfide results in increased expression of KIT protein CTD PMID:23663050 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Klf2 KLF transcription factor 2 increases expression
multiple interactions		 EXP diallyl disulfide results in increased expression of KLF2 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of KLF2 mRNA		 CTD PMID:31077537 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Malsu1 mitochondrial assembly of ribosomal large subunit 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of MALSU1 mRNA CTD PMID:31077537 NCBI chr 4:78,051,090...78,059,913
Ensembl chr 4:78,051,059...78,059,905 		JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 affects expression ISO diallyl disulfide affects the expression of MAP2K7 protein CTD PMID:21695758 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222 		JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 affects expression ISO diallyl disulfide affects the expression of MAP3K3 protein CTD PMID:21695758 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases expression
increases phosphorylation		 EXP
ISO		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl disulfide results in increased phosphorylation of MAPK1 protein]
diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK1 protein]
diallyl disulfide results in decreased expression of MAPK1 protein		 CTD PMID:17263507 PMID:21695758 PMID:34896185 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
decreases expression		 EXP
ISO		 diallyl disulfide results in increased phosphorylation of MAPK3 protein
diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK3 protein]
diallyl disulfide results in decreased expression of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl disulfide results in increased phosphorylation of MAPK3 protein]		 CTD PMID:17263507 PMID:21695758 PMID:34896185 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions		 ISO diallyl disulfide results in increased phosphorylation of MAPK8 protein
diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]
diallyl disulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein		 CTD PMID:14522920 PMID:17647244 PMID:34896185 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of MDM2 mRNA CTD PMID:31077537 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression		 ISO diallyl disulfide results in decreased expression of and results in decreased activity of MMP2 protein
diallyl disulfide results in decreased expression of MMP2 mRNA; diallyl disulfide results in decreased expression of MMP2 protein		 CTD PMID:20600798 PMID:21695758 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO diallyl disulfide results in decreased expression of MMP7 protein CTD PMID:21695758 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
affects expression
decreases expression		 ISO diallyl disulfide results in decreased expression of and results in decreased activity of MMP9 protein
diallyl disulfide affects the expression of MMP9 protein
diallyl disulfide results in decreased expression of MMP9 mRNA		 CTD PMID:20600798 PMID:21695758 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of MOGS mRNA CTD PMID:31077537 NCBI chr 4:115,621,623...115,625,026
Ensembl chr 4:115,621,623...115,625,032 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
decreases expression
decreases degradation		 EXP
ISO		 diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of and affects the localization of NFE2L2 protein]
diallyl disulfide results in decreased expression of NFE2L2 mRNA
diallyl disulfide affects the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NFE2L2 protein]; diallyl disulfide inhibits the reaction [Ethanol affects the expression of NFE2L2 protein]; diallyl disulfide results in increased expression of and affects the localization of NFE2L2 protein; NFE2L2 protein affects the reaction [diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of GCLC mRNA]]; NFE2L2 protein affects the reaction [diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 mRNA]]; NFE2L2 protein affects the reaction [diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]]; NFE2L2 protein affects the reaction [diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of GCLM mRNA]]; NFE2L2 protein affects the reaction [diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]]
diallyl disulfide results in decreased degradation of NFE2L2 protein		 CTD PMID:24293383 PMID:34896185 PMID:35526736 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
multiple interactions
increases expression		 ISO
EXP		 diallyl disulfide results in increased phosphorylation of NFKBIA protein
diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of NFKBIA protein modified form]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of NFKBIA protein modified form]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of NFKBIA protein]
[Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of NFKBIA mRNA
diallyl disulfide results in increased expression of NFKBIA mRNA		 CTD PMID:23663050 PMID:31077537 PMID:34896185 PMID:35526736 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of NLRP3 protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NLRP3 protein] CTD PMID:34896185 PMID:35526736 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos2 nitric oxide synthase 2 affects expression
multiple interactions		 ISO diallyl disulfide affects the expression of NOS2 protein
diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of NOS2 protein]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of NOS2 protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]		 CTD PMID:21695758 PMID:34896185 PMID:35526736 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
increases phosphorylation
decreases degradation		 ISO diallyl disulfide promotes the reaction [NOS3 protein binds to CAV1 protein]; wortmannin inhibits the reaction [diallyl disulfide results in increased phosphorylation of NOS3 protein]
diallyl disulfide results in increased expression of NOS3 protein
diallyl disulfide results in decreased degradation of NOS3 protein		 CTD PMID:20229525 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
multiple interactions
increases expression		 EXP
ISO		 diallyl disulfide results in increased activity of NQO1 protein
diallyl disulfide inhibits the reaction [Ethanol results in increased expression of NQO1 protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 mRNA]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 protein]; diallyl disulfide promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NQO1 protein]; NFE2L2 protein affects the reaction [diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NQO1 mRNA]]
diallyl disulfide results in increased expression of NQO1 mRNA; diallyl disulfide results in increased expression of NQO1 protein
diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]; diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 protein]		 CTD PMID:8339252 PMID:24293383 PMID:34896185 PMID:35526736 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein] CTD PMID:30677442 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of PMP22 mRNA CTD PMID:31077537 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions ISO diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in decreased expression of PPARA protein]; diallyl disulfide inhibits the reaction [Ethanol results in decreased expression of PPARA protein] CTD PMID:35526736 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of PPP3CA mRNA CTD PMID:31077537 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression
multiple interactions		 ISO diallyl disulfide affects the expression of PTGS2 protein
diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of PTGS2 protein]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]		 CTD PMID:21695758 PMID:35526736 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of PYCARD protein]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of PYCARD protein] CTD PMID:35526736 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased expression of RELA protein modified form]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of RELA protein modified form]; diallyl disulfide inhibits the reaction [Ethanol results in increased expression of RELA protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of RELA protein] CTD PMID:34896185 PMID:35526736 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Sesn2 sestrin 2 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SESN2 mRNA CTD PMID:31077537 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
G Sfn stratifin multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SFN mRNA CTD PMID:31077537 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO diallyl disulfide results in decreased expression of SNAI1 mRNA; diallyl disulfide results in decreased expression of SNAI1 protein CTD PMID:20600798 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of SOD1 mRNA] CTD PMID:24293383 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO diallyl disulfide inhibits the reaction [Ethanol results in increased expression of SREBF1 protein] CTD PMID:35526736 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Stag1 stromal antigen 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of STAG1 mRNA CTD PMID:31077537 NCBI chr 8:101,179,039...101,564,684
Ensembl chr 8:101,179,039...101,564,677 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SUMO1 mRNA CTD PMID:31077537 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Tfdp2 transcription factor Dp-2 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TFDP2 mRNA CTD PMID:31077537 NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO diallyl disulfide results in increased expression of TIMP1 mRNA CTD PMID:20600798 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO diallyl disulfide results in increased expression of TIMP2 mRNA CTD PMID:20600798 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases secretion		 ISO diallyl disulfide inhibits the reaction [[Ethanol co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; diallyl disulfide inhibits the reaction [Ethanol results in increased secretion of TNF protein]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF protein]; NFE2L2 protein affects the reaction [diallyl disulfide inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]]
diallyl disulfide results in decreased secretion of TNF protein		 CTD PMID:34896185 PMID:35526736 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP8 protein]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP9 protein]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein] CTD PMID:30677442 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression		 ISO
EXP		 Acetylcysteine inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]; Glutathione inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]; TP53 protein affects the reaction [diallyl disulfide results in increased expression of GDF15 protein]
[Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TP53 mRNA		 CTD PMID:11925476 PMID:19202565 PMID:31077537 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tsg101 tumor susceptibility 101 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TSG101 mRNA CTD PMID:31077537 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO diallyl disulfide inhibits the reaction [Ethanol results in decreased expression of TXNRD1 protein] CTD PMID:35526736 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of UBE2H mRNA CTD PMID:31077537 NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases activity EXP diallyl disulfide results in increased activity of UGT1A1 protein CTD PMID:8339252 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO diallyl disulfide results in decreased expression of XIAP protein CTD PMID:17647244 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
dibenzothiazol-2-yl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO [dibenzothiazyl disulfide co-treated with Sodium Dodecyl Sulfate] results in increased expression of IFNG protein CTD PMID:12062936 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il4 interleukin 4 multiple interactions ISO [dibenzothiazyl disulfide co-treated with Sodium Dodecyl Sulfate] results in increased expression of IL4 protein CTD PMID:12062936 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
dipropyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO n-propyl disulfide results in decreased activity of CYP1A1 protein CTD PMID:18339364 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO n-propyl disulfide results in decreased activity of CYP2E1 protein CTD PMID:18339364 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP n-propyl disulfide results in increased expression of CYP3A2 protein CTD PMID:16000231 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
disulfiram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of AARS1 mRNA CTD PMID:24690739 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147 		JBrowse link
G Abat 4-aminobutyrate aminotransferase multiple interactions EXP [Ethanol co-treated with Disulfiram] results in decreased activity of ABAT protein; [Ethanol co-treated with Disulfiram] results in decreased expression of ABAT mRNA CTD PMID:9591243 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835 		JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCA1 mRNA CTD PMID:24690739 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCA3 mRNA CTD PMID:24690739 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions		 ISO Disulfiram results in decreased activity of ABCB11 protein
Disulfiram inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]		 CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity
multiple interactions		 ISO Disulfiram metabolite results in decreased activity of ABCB1 protein; Disulfiram results in decreased activity of ABCB1 protein
Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein]		 CTD PMID:10841824 PMID:14978246 PMID:16028354 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions		 ISO Disulfiram results in decreased activity of ABCC1 protein
Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC1 protein]		 CTD PMID:14978246 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC4 protein]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:14978246 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCG1 mRNA CTD PMID:24690739 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Acad11 acyl-CoA dehydrogenase family, member 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACAD11 mRNA CTD PMID:24690739 NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560 		JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression ISO Disulfiram results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ache acetylcholinesterase decreases expression EXP Disulfiram results in decreased expression of ACHE protein CTD PMID:3868355 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACSS2 mRNA CTD PMID:24690739 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACTA2 mRNA CTD PMID:24690739 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADAM9 mRNA CTD PMID:24690739 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ADAMTS1 mRNA CTD PMID:24690739 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADARB1 mRNA CTD PMID:24690739 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852 		JBrowse link
G Adcy3 adenylate cyclase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADCY3 mRNA CTD PMID:24690739 NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686 		JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADGRE5 mRNA CTD PMID:24690739 NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638 		JBrowse link
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide decreases activity EXP Disulfiram results in decreased activity of ADH1 protein CTD PMID:15551062 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892 		JBrowse link
G Adm adrenomedullin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ADM mRNA CTD PMID:24690739 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of AFAP1 mRNA CTD PMID:24690739 NCBI chr14:74,743,322...74,856,295
Ensembl chr14:74,743,320...74,856,263 		JBrowse link
G Agxt alanine--glyoxylate aminotransferase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AGXT mRNA CTD PMID:24690739 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336 		JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 multiple interactions EXP [Ethanol co-treated with Disulfiram] results in decreased activity of AGXT2 protein CTD PMID:9591243 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926 		JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AHSA1 mRNA CTD PMID:24690739 NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases expression ISO Disulfiram results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Disulfiram results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Disulfiram results in increased expression of AKR1C1 mRNA CTD PMID:20566472 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Disulfiram results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Alad aminolevulinate dehydratase multiple interactions EXP [Disulfiram co-treated with Lead] results in decreased activity of ALAD protein CTD PMID:2748540 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases activity
decreases expression
multiple interactions		 EXP
ISO		 Disulfiram results in decreased activity of ALDH1A1 protein
Disulfiram results in decreased expression of ALDH1A1 mRNA; Disulfiram results in decreased expression of ALDH1A1 protein
Disulfiram inhibits the reaction [ALDH1A1 protein results in decreased susceptibility to maphosphamide]		 CTD PMID:8562935 PMID:10998257 PMID:21035945 PMID:34242567 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases activity ISO Disulfiram results in decreased activity of ALDH1A2 protein CTD PMID:22079344 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity
decreases expression
multiple interactions		 ISO
EXP		 Disulfiram metabolite results in decreased activity of ALDH2 protein; Disulfiram results in decreased activity of ALDH2 protein
Disulfiram results in decreased expression of ALDH2 mRNA
[Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyoxal; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Pyruvaldehyde		 CTD PMID:9585485 PMID:10513990 PMID:11142365 PMID:21334317 PMID:21376711 More... NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases metabolic processing ISO ALDH3A1 protein results in increased metabolism of Disulfiram CTD PMID:18591790 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681 		JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ANGPTL4 mRNA CTD PMID:24690739 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ano6 anoctamin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ANO6 mRNA CTD PMID:24690739 NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589 		JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of APBB3 mRNA CTD PMID:24690739 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094 		JBrowse link
G Apcdd1l APC down-regulated 1 like multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of APCDD1L mRNA CTD PMID:24690739 NCBI chr 3:162,587,484...162,658,362
Ensembl chr 3:162,582,252...162,658,073 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of APP mRNA CTD PMID:24690739 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Ar androgen receptor multiple interactions ISO [Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein; Disulfiram inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:19789329 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ARC mRNA CTD PMID:24690739 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Asgr1 asialoglycoprotein receptor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ASGR1 mRNA CTD PMID:24690739 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631 		JBrowse link
G Asmtl acetylserotonin O-methyltransferase-like multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ASMTL mRNA CTD PMID:24690739 NCBI chr12:16,315,335...16,321,607
Ensembl chr12:16,315,414...16,318,080 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ASNS mRNA CTD PMID:24690739 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of ATF1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF1 protein] CTD PMID:15367699 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670 		JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of ATF2 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF2 protein] CTD PMID:15367699 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression		 ISO [Disulfiram binds to Copper] which results in decreased expression of ATF3 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA] CTD PMID:24690739 PMID:32661532 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atg101 autophagy related 101 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATG101 mRNA CTD PMID:24690739 NCBI chr 7:132,398,477...132,407,643
Ensembl chr 7:132,398,483...132,407,633 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression EXP Disulfiram results in decreased expression of ATP2B1 mRNA CTD PMID:15003327 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Atp5mk ATP synthase membrane subunit K multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP5MK mRNA CTD PMID:24690739 NCBI chr 1:245,973,910...245,980,702
Ensembl chr 1:245,973,914...245,980,761 		JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP6V0D1 mRNA CTD PMID:24690739 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450 		JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP6V1G1 mRNA CTD PMID:24690739 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463 		JBrowse link
G Atxn1l ataxin 1-like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATXN1L mRNA CTD PMID:24690739 NCBI chr19:37,700,341...37,711,524
Ensembl chr19:37,700,106...37,711,538 		JBrowse link
G Atxn3 ataxin 3 increases response to substance
affects localization		 ISO ATXN3 protein alternative form results in increased susceptibility to Disulfiram
Disulfiram affects the localization of ATXN3 protein alternative form		 CTD PMID:31378764 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902 		JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BAG3 mRNA CTD PMID:24690739 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein CTD PMID:24126434 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO Disulfiram results in increased expression of BAX protein
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [Copper co-treated with Disulfiram] results in increased expression of BAX protein		 CTD PMID:17079463 PMID:23033007 PMID:24126434 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of BBS2 mRNA CTD PMID:24690739 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993 		JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BCCIP mRNA CTD PMID:24690739 NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:188,512,367...188,524,958 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Copper co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein CTD PMID:21911303 PMID:23033007 PMID:24126434 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of BDNF mRNA CTD PMID:24690739 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression EXP Disulfiram results in increased expression of BGLAP mRNA CTD PMID:24496638 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495 		JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA] CTD PMID:22285649 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Brf2 BRF2, RNA polymerase III transcription initiation factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BRF2 mRNA CTD PMID:24690739 NCBI chr16:64,928,334...64,933,057
Ensembl chr16:64,928,300...64,933,059 		JBrowse link
G Btk Bruton tyrosine kinase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BTK mRNA CTD PMID:24690739 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853 		JBrowse link
G C1r complement C1r multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of C1R mRNA CTD PMID:24690739 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C1s complement C1s multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of C1S mRNA CTD PMID:24690739 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303 		JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CACYBP mRNA CTD PMID:24690739 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177 		JBrowse link
G Calcb calcitonin-related polypeptide, beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CALCB mRNA CTD PMID:24690739 NCBI chr 1:168,966,465...168,970,125
Ensembl chr 1:168,966,465...168,970,125 		JBrowse link
G Cald1 caldesmon 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CALD1 mRNA CTD PMID:24690739 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CA2 mRNA CTD PMID:24690739 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car7 carbonic anhydrase 7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CA7 mRNA CTD PMID:24690739 NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 EXP
ISO		 [Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]
[Disulfiram binds to Copper] which results in increased activity of CASP3 protein
[Disulfiram binds to Copper] which results in increased activity of CASP3 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of CASP3 protein]
Disulfiram results in increased activity of CASP3 protein		 CTD PMID:11239917 PMID:17026967 PMID:17079463 PMID:24193513 PMID:24690739 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases activity ISO Disulfiram results in increased activity of CASP7 protein CTD PMID:17026967 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased activity of CASP9 protein CTD PMID:24690739 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase increases expression
multiple interactions
decreases expression		 ISO Disulfiram results in increased expression of CAT mRNA
Zinc Sulfate inhibits the reaction [Disulfiram results in decreased expression of CAT mRNA]		 CTD PMID:20566472 PMID:32712770 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CCAR1 protein CTD PMID:24690739 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526 		JBrowse link
G Ccdc59 coiled-coil domain containing 59 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCDC59 mRNA CTD PMID:24690739 NCBI chr 7:41,142,760...41,149,143
Ensembl chr 7:41,142,760...41,149,143 		JBrowse link
G Ccdc92 coiled-coil domain containing 92 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CCDC92 mRNA CTD PMID:24690739 NCBI chr12:31,796,102...31,823,333
Ensembl chr12:31,796,684...31,823,337 		JBrowse link
G Cck cholecystokinin decreases expression
multiple interactions		 EXP
ISO		 Disulfiram results in decreased expression of CCK protein alternative form
[Disulfiram binds to Copper] which results in decreased expression of CCK mRNA		 CTD PMID:8246921 PMID:24690739 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion		 ISO [Disulfiram binds to Copper] which results in increased expression of CCL2 mRNA; [Zinc Sulfate co-treated with Disulfiram] inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; Disulfiram inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Disulfiram results in decreased secretion of CCL2 protein		 CTD PMID:24690739 PMID:32712770 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCL26 mRNA CTD PMID:24690739 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein]
[Disulfiram binds to Copper] which results in increased expression of CCL5 mRNA		 CTD PMID:19016906 PMID:24690739 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased expression of CCNA2 protein CTD PMID:15367699 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577 		JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA] CTD PMID:22285649 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Ccnk cyclin K multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCNK mRNA CTD PMID:24690739 NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191 		JBrowse link
G Ccpg1 cell cycle progression 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CCPG1 mRNA CTD PMID:24690739 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Disulfiram results in increased expression of CCR2 protein CTD PMID:32712770 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 multiple interactions ISO Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein] CTD PMID:19016906 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cd163 CD163 molecule multiple interactions
decreases expression		 ISO [Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD163 mRNA
Disulfiram results in decreased expression of CD163 mRNA		 CTD PMID:32712770 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878 		JBrowse link
G Cd36 CD36 molecule multiple interactions
decreases expression		 ISO [Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD36 mRNA
Disulfiram results in decreased expression of CD36 mRNA		 CTD PMID:32712770 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd46 CD46 molecule multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD46 mRNA CTD PMID:24690739 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445 		JBrowse link
G Cd47 Cd47 molecule multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD47 mRNA CTD PMID:24690739 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425 		JBrowse link
G Cd9 CD9 molecule multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD9 mRNA CTD PMID:24690739 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222 		JBrowse link
G Cdc42ep5 CDC42 effector protein 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDC42EP5 mRNA CTD PMID:24690739 NCBI chr 1:70,035,921...70,038,990 JBrowse link
G Cdh11 cadherin 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDH11 mRNA CTD PMID:24690739 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDH2 mRNA CTD PMID:24690739 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDK5R1 mRNA CTD PMID:24690739 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDK5RAP3 mRNA CTD PMID:24690739 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions		 ISO Disulfiram results in increased expression of CDKN1B protein
[Disulfiram binds to Copper] which results in increased expression of CDKN1B protein		 CTD PMID:17079463 PMID:24690739 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDKN1C mRNA CTD PMID:24690739 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2aip CDKN2A interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDKN2AIP mRNA CTD PMID:24690739 NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CEMIP mRNA CTD PMID:24690739 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Cenpw centromere protein W multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CENPW mRNA CTD PMID:24690739 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464 		JBrowse link
G Cfap53 cilia and flagella associated protein 53 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CFAP53 mRNA CTD PMID:24690739 NCBI chr18:67,884,651...67,955,873
Ensembl chr18:67,869,855...67,952,318 		JBrowse link
G Cfb complement factor B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CFB mRNA CTD PMID:24690739 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Chga chromogranin A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHGA mRNA CTD PMID:24690739 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chmp1b charged multivesicular body protein 1B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHMP1B mRNA CTD PMID:24690739 NCBI chr18:60,740,349...60,742,879 JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHORDC1 mRNA CTD PMID:24690739 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162 		JBrowse link
G Cilp cartilage intermediate layer protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CILP mRNA CTD PMID:24690739 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251 		JBrowse link
G Cirbp cold inducible RNA binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CIRBP mRNA CTD PMID:24690739 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Ckap4 cytoskeleton-associated protein 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CKAP4 mRNA CTD PMID:24690739 NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914 		JBrowse link
G Cldn1 claudin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CLDN1 mRNA CTD PMID:24690739 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724 		JBrowse link
G Clec7a C-type lectin domain containing 7A increases expression ISO Disulfiram results in increased expression of CLEC7A protein CTD PMID:32712770 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897 		JBrowse link
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CLP1 mRNA CTD PMID:24690739 NCBI chr 3:69,806,774...69,818,633
Ensembl chr 3:69,806,778...69,810,421 		JBrowse link
G Clta clathrin, light chain A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CLTA mRNA CTD PMID:24690739 NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472 		JBrowse link
G Cmklr2 chemerin chemokine-like receptor 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CMKLR2 mRNA CTD PMID:24690739 NCBI chr 9:64,583,310...64,618,127
Ensembl chr 9:64,585,594...64,586,655 		JBrowse link
G Cntnap1 contactin associated protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CNTNAP1 mRNA CTD PMID:24690739 NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611 		JBrowse link
G Col12a1 collagen type XII alpha 1 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL12A1 mRNA CTD PMID:24690739 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686 		JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL1A2 mRNA CTD PMID:24690739 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL3A1 mRNA CTD PMID:24690739 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL4A1 mRNA CTD PMID:24690739 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col5a1 collagen type V alpha 1 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL5A1 mRNA CTD PMID:24690739 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Commd9 COMM domain containing 9 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of COMMD9 mRNA CTD PMID:24690739 NCBI chr 3:88,175,909...88,190,427
Ensembl chr 3:88,175,987...88,190,439 		JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA CTD PMID:24690739 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of CREB1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of CREB1 protein] CTD PMID:15367699 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRELD2 mRNA CTD PMID:24690739 NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543 		JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CRIM1 mRNA CTD PMID:24690739 NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259 		JBrowse link
G Cript CXXC repeat containing interactor of PDZ3 domain multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRIPT mRNA CTD PMID:24690739 NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399 		JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRISPLD2 mRNA CTD PMID:24690739 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465 		JBrowse link
G Cryab crystallin, alpha B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRYAB mRNA CTD PMID:24690739 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157 		JBrowse link
G Cse1l chromosome segregation 1 like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CSE1L mRNA CTD PMID:24690739 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865 		JBrowse link
G Csnk1e casein kinase 1, epsilon multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CSNK1E mRNA CTD PMID:24690739 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794 		JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AXUD1 mRNA CTD PMID:24690739 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183 		JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CSRP2 mRNA CTD PMID:24690739 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745 		JBrowse link
G Cst6 cystatin E/M multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CST6 mRNA CTD PMID:24690739 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030 		JBrowse link
G Cth cystathionine gamma-lyase increases expression ISO Disulfiram results in increased expression of CTH protein CTD PMID:34242567 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Cwc25 CWC25 spliceosome-associated protein homolog multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CWC25 mRNA CTD PMID:24690739 NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CXCR4 mRNA CTD PMID:24690739 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA] CTD PMID:22285649 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA] CTD PMID:22285649 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO Disulfiram results in decreased activity of CYP1A1 protein CTD PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Disulfiram results in decreased activity of CYP1B1 protein CTD PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression		 EXP GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA] CTD PMID:8390837 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052 		JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
multiple interactions		 EXP Disulfiram results in increased expression of CYP2B2 mRNA
GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA]		 CTD PMID:8390837 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity
decreases expression		 EXP Disulfiram results in decreased activity of CYP2C11 protein
Disulfiram results in decreased expression of CYP2C11 protein		 CTD PMID:9393675 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
decreases expression		 ISO
EXP		 [Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene; Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane]
Disulfiram results in decreased expression of CYP2E1 mRNA; Disulfiram results in decreased expression of CYP2E1 protein
Disulfiram binds to and results in decreased activity of CYP2E1 protein		 CTD PMID:1664256 PMID:8637342 PMID:9393675 PMID:10805064 PMID:18754103 More... NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CYP2R1 mRNA CTD PMID:24690739 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
increases response to substance
decreases activity		 EXP
ISO		 Disulfiram results in decreased expression of CYP3A2 mRNA
CYP3A4 protein results in increased susceptibility to Disulfiram
Disulfiram results in decreased activity of CYP3A2 protein		 CTD PMID:9393675 PMID:21540358 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Dag1 dystroglycan 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DAG1 mRNA CTD PMID:24690739 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Dbh dopamine beta-hydroxylase decreases activity
affects response to substance		 ISO Disulfiram results in decreased activity of DBH protein
DBH gene SNP affects the susceptibility to Disulfiram
DBH gene polymorphism affects the susceptibility to Disulfiram		 CTD PMID:90468 PMID:16163519 PMID:19462300 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DCAF13 mRNA CTD PMID:24690739 NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142 		JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO [Disulfiram co-treated with NADP] binds to DCXR protein CTD PMID:25526675 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DDIT3 mRNA CTD PMID:24690739 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Ddx39a DExD-box helicase 39A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DDX39A mRNA CTD PMID:24690739 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954 		JBrowse link
G Ddx60 DEXD/H-box helicase 60 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DDX60 mRNA CTD PMID:24690739 NCBI chr16:28,077,000...28,197,903
Ensembl chr16:28,076,999...28,179,526 		JBrowse link
G Dedd2 death effector domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DEDD2 mRNA CTD PMID:24690739 NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714 		JBrowse link
G Dhdh dihydrodiol dehydrogenase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DHDH mRNA CTD PMID:24690739 NCBI chr 1:95,954,361...95,965,262
Ensembl chr 1:95,953,092...95,965,197 		JBrowse link
G Dhrs2 dehydrogenase/reductase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DHRS2 mRNA CTD PMID:24690739 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644 		JBrowse link
G Dhrs3 dehydrogenase/reductase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DHRS3 mRNA CTD PMID:24690739 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417 		JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DKK3 mRNA CTD PMID:24690739 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DLL1 mRNA CTD PMID:24690739 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJA1 mRNA CTD PMID:24690739 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967 		JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJA4 mRNA CTD PMID:24690739 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJB1 mRNA CTD PMID:24690739 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJB6 mRNA CTD PMID:24690739 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJC3 mRNA CTD PMID:24690739 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Dph3 diphthamide biosynthesis 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DPH3 mRNA CTD PMID:24690739 NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265 		JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DRAM1 mRNA CTD PMID:24690739 NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765 		JBrowse link
G Dse dermatan sulfate epimerase multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DSE mRNA CTD PMID:24690739 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992 		JBrowse link
G Dusp2 dual specificity phosphatase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DUSP2 mRNA CTD PMID:24690739 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499 		JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DUSP5 mRNA CTD PMID:24690739 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818 		JBrowse link
G Dynll2 dynein light chain LC8-type 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DYNLL2 mRNA CTD PMID:24690739 NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805 		JBrowse link
G Eaf1 ELL associated factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EAF1 mRNA CTD PMID:24690739 NCBI chr16:6,698,322...6,713,071
Ensembl chr16:6,698,322...6,713,071 		JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of EDIL3 mRNA CTD PMID:24690739 NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008 		JBrowse link
G Eed embryonic ectoderm development multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EED mRNA CTD PMID:24690739 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974 		JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of EFEMP1 mRNA CTD PMID:24690739 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018 		JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EGR1 mRNA CTD PMID:24690739 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EIF4A3 mRNA CTD PMID:24690739 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ELL2 mRNA CTD PMID:24690739 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781 		JBrowse link
G Elof1 elongation factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ELOF1 mRNA CTD PMID:24690739 NCBI chr 8:20,645,336...20,650,888
Ensembl chr 8:20,645,336...20,650,579 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Disulfiram binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ETS1 mRNA CTD PMID:24690739 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G F12 coagulation factor XII multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of F12 mRNA CTD PMID:24690739 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530 		JBrowse link
G Fam210a family with sequence similarity 210, member A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FAM210A mRNA CTD PMID:24690739 NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171 		JBrowse link
G Fam234a family with sequence similarity 234, member A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of FAM234A mRNA CTD PMID:24690739 NCBI chr10:15,232,267...15,263,529
Ensembl chr10:15,232,278...15,263,488 		JBrowse link
G Fam32a family with sequence similarity 32, member A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FAM32A mRNA CTD PMID:24690739 NCBI chr16:17,603,054...17,607,376
Ensembl chr16:17,603,946...17,607,398 		JBrowse link
G Fech ferrochelatase increases expression ISO Disulfiram results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FKBP1A mRNA CTD PMID:24690739 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743 		JBrowse link
G Flcn folliculin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FLCN mRNA CTD PMID:24690739 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769 		JBrowse link
G Fndc11 fibronectin type III domain containing 11 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FNDC11 mRNA CTD PMID:24690739 NCBI chr 3:168,330,607...168,333,111
Ensembl chr 3:168,330,602...168,334,617 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOS mRNA CTD PMID:24690739 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOSB mRNA CTD PMID:24690739 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Foxa3 forkhead box A3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOXA3 mRNA CTD PMID:24690739 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155 		JBrowse link
G Foxj1 forkhead box J1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOXJ1 mRNA CTD PMID:24690739 NCBI chr10:101,566,299...101,570,249
Ensembl chr10:101,566,304...101,570,237 		JBrowse link
G Frg1 FSHD region gene 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FRG1 mRNA CTD PMID:24690739 NCBI chr16:50,925,783...50,946,661
Ensembl chr16:50,925,803...50,946,661 		JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA] CTD PMID:22285649 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Fstl1 follistatin-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of FSTL1 mRNA CTD PMID:24690739 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677 		JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FTCD mRNA CTD PMID:24690739 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735 		JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Disulfiram results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Disulfiram results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GADD45B mRNA CTD PMID:24690739 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046 		JBrowse link
G Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GALNT10 mRNA CTD PMID:24690739 NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013 		JBrowse link
G Gas6 growth arrest specific 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GAS6 mRNA CTD PMID:24690739 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gata2 GATA binding protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GATA2 mRNA CTD PMID:24690739 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761 		JBrowse link
G Gbp4 guanylate binding protein 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GBP4 mRNA CTD PMID:24690739 NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879 		JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GCC1 mRNA CTD PMID:24690739 NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663 		JBrowse link
G Gcgr glucagon receptor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GCGR mRNA CTD PMID:24690739 NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Disulfiram results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Disulfiram results in increased expression of GCLM mRNA CTD PMID:20566472 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535 		JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GEM mRNA CTD PMID:24690739 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222 		JBrowse link
G Gemin6 gem (nuclear organelle) associated protein 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GEMIN6 mRNA CTD PMID:24690739 NCBI chr 6:14,786,086...14,790,631
Ensembl chr 6:14,786,070...14,790,612 		JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA]; GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA] CTD PMID:8390837 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Glg1 golgi glycoprotein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GLG1 mRNA CTD PMID:24690739 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178 		JBrowse link
G Glrx2 glutaredoxin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GLRX2 mRNA CTD PMID:24690739 NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831 		JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GOSR2 mRNA CTD PMID:24690739 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GPSM1 mRNA CTD PMID:24690739 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GPT2 mRNA CTD PMID:24690739 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610 		JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Disulfiram results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gramd1a GRAM domain containing 1A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GRAMD1A mRNA CTD PMID:24690739 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336 		JBrowse link
G Gramd2b GRAM domain containing 2B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GRAMD2B mRNA CTD PMID:24690739 NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953 		JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GRWD1 mRNA CTD PMID:24690739 NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201 		JBrowse link
G Gsdmd gasdermin D multiple interactions
decreases cleavage		 ISO Disulfiram binds to and results in decreased activity of GSDMD protein; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of GSDMD protein]
Disulfiram results in decreased cleavage of GSDMD protein		 CTD PMID:32367036 PMID:33851234 NCBI chr 7:107,542,242...107,547,052
Ensembl chr 7:107,542,083...107,547,055 		JBrowse link
G Gsdme gasdermin E multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GSDME mRNA CTD PMID:24690739 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Disulfiram results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gtf2b general transcription factor IIB multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GTF2B mRNA CTD PMID:24690739 NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651 		JBrowse link
G H2ac20 H2A clustered histone 20 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2AC20 mRNA CTD PMID:24690739 NCBI chr 2:183,779,879...183,780,324 JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Disulfiram inhibits the reaction [captax results in increased expression of H2AX protein]; Disulfiram inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein] CTD PMID:28300663 PMID:35279910 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239 		JBrowse link
G H2bc12 H2B clustered histone 12 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2BC12 mRNA CTD PMID:24690739 NCBI chr17:42,485,746...42,486,126 JBrowse link
G H2bc8 H2B clustered histone 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2BC8 mRNA CTD PMID:24690739 NCBI chr17:42,708,646...42,709,435 JBrowse link
G H3f4 H3.4 histone, cluster member multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H3-4 mRNA CTD PMID:24690739 NCBI chr10:43,740,797...43,741,207 JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of H6PD mRNA CTD PMID:24690739 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HBA1 mRNA CTD PMID:24690739 NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HBEGF mRNA CTD PMID:24690739 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HES1 mRNA CTD PMID:24690739 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192 		JBrowse link
G Hes6 hes family bHLH transcription factor 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HES6 mRNA CTD PMID:24690739 NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559 		JBrowse link
G Hist1h3b histone cluster 1, H3b multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H3C12 mRNA CTD PMID:24690739 NCBI chr17:42,722,805...42,723,925
Ensembl chr17:42,723,450...42,723,911 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO Disulfiram results in increased expression of HMOX1 mRNA
[Disulfiram binds to Copper] which results in decreased expression of HMOX1 mRNA; [Disulfiram co-treated with Zinc Sulfate] results in increased expression of HMOX1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]		 CTD PMID:20566472 PMID:24690739 PMID:32661532 PMID:32712770 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HNRNPA2B1 mRNA CTD PMID:24690739 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hoxa1 homeobox A1 multiple interactions ISO Disulfiram inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] CTD PMID:23696197 NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504 		JBrowse link
G Hoxd1 homeo box D1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HOXD1 mRNA CTD PMID:24690739 NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769 		JBrowse link
G Hrk harakiri, BCL2 interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HRK mRNA CTD PMID:24690739 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HS3ST2 mRNA CTD PMID:24690739 NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions ISO [Disulfiram co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO Disulfiram results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSP90AA1 mRNA CTD PMID:24690739 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSP90AB1 mRNA CTD PMID:24690739 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression
multiple interactions		 ISO Disulfiram results in increased expression of HSPA1B mRNA
[Disulfiram binds to Copper] which results in decreased expression of HSPA1B mRNA		 CTD PMID:20566472 PMID:24690739 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA1A mRNA CTD PMID:24690739 NCBI chr20:3,870,765...3,873,221 JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA1L mRNA CTD PMID:24690739 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA4 mRNA CTD PMID:24690739 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Hspa6l-ps1 heat shock protein family A (Hsp70) member 6 like, pseudogene 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA6 mRNA CTD PMID:24690739 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA8 mRNA CTD PMID:24690739 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPB1 mRNA CTD PMID:24690739 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPB8 mRNA CTD PMID:24690739 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPH1 mRNA CTD PMID:24690739 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HTR2B mRNA CTD PMID:24690739 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ID2 mRNA CTD PMID:24690739 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Ier5 immediate early response 5 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of IER5 mRNA CTD PMID:24690739 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFIT2 mRNA CTD PMID:24690739 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFIT3 mRNA CTD PMID:24690739 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Ifngr2 interferon gamma receptor 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFNGR2 mRNA CTD PMID:24690739 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IGF2R mRNA CTD PMID:24690739 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IGFBP7 mRNA; [Disulfiram binds to Copper] which results in increased expression of IGFBP7 protein CTD PMID:24690739 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314 		JBrowse link
G Il18 interleukin 18 multiple interactions ISO [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein] CTD PMID:33579316 PMID:33851234 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL1A mRNA CTD PMID:24690739 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL1B mRNA; [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL1B protein]; Disulfiram inhibits the reaction [Nigericin results in increased secretion of IL1B protein]
Disulfiram inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]		 CTD PMID:24690739 PMID:32367036 PMID:32712770 PMID:33579316 PMID:33851234 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL6 mRNA; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL6 protein] CTD PMID:24690739 PMID:32712770 PMID:33851234 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of INSIG1 mRNA CTD PMID:24690739 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Irf8 interferon regulatory factor 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of IRF8 mRNA CTD PMID:24690739 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829 		JBrowse link
G Isy1 ISY1 splicing factor homolog multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ISY1 mRNA CTD PMID:24690739 NCBI chr 4:120,276,535...120,297,227
Ensembl chr 4:120,276,292...120,297,188 		JBrowse link
G Itga11 integrin subunit alpha 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGA11 mRNA CTD PMID:24690739 NCBI chr 8:63,145,950...63,254,717
Ensembl chr 8:63,146,001...63,254,407 		JBrowse link
G Itga3 integrin subunit alpha 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGA3 mRNA CTD PMID:24690739 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118 		JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Disulfiram results in increased expression of ITGAM protein CTD PMID:32712770 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGAV mRNA CTD PMID:24690739 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGB1 mRNA CTD PMID:24690739 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Itgb5 integrin subunit beta 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGB5 mRNA CTD PMID:24690739 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472 		JBrowse link
G Jag2 jagged canonical Notch ligand 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of JAG2 mRNA CTD PMID:24690739 NCBI chr 6:131,983,056...132,005,359
Ensembl chr 6:131,983,056...132,005,818 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased expression of and results in increased phosphorylation of JUN protein; [Copper co-treated with Disulfiram] results in increased expression of and results in increased phosphorylation of JUN protein; [Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [[Copper co-treated with Disulfiram] results in increased phosphorylation of JUN protein]; pyrazolanthrone inhibits the reaction [[Disulfiram co-treated with Copper co-treated with Doxorubicin] results in increased phosphorylation of and results in increased expression of JUN protein] CTD PMID:21911303 PMID:23033007 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KCNG1 mRNA CTD PMID:24690739 NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635 		JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KHDRBS3 mRNA CTD PMID:24690739 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460 		JBrowse link
G Klf10 KLF transcription factor 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KLF10 mRNA CTD PMID:24690739 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994 		JBrowse link
G Klhl22 kelch-like family member 22 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KLHL22 mRNA CTD PMID:24690739 NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770 		JBrowse link
G Klhl5 kelch-like family member 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KLHL5 mRNA CTD PMID:24690739 NCBI chr14:43,144,254...43,206,192
Ensembl chr14:43,144,257...43,184,238 		JBrowse link
G Krt75 keratin 75 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KRT75 mRNA CTD PMID:24690739 NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345 		JBrowse link
G Lamc1 laminin subunit gamma 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LAMC1 mRNA CTD PMID:24690739 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LAMTOR3 mRNA CTD PMID:24690739 NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607 		JBrowse link
G Lemd2 LEM domain nuclear envelope protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LEMD2 mRNA CTD PMID:24690739 NCBI chr20:5,282,397...5,296,621
Ensembl chr20:5,282,397...5,296,626 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521 		JBrowse link
G Limch1 LIM and calponin homology domains 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LIMCH1 mRNA CTD PMID:24690739 NCBI chr14:41,112,579...41,425,185
Ensembl chr14:41,114,803...41,425,191 		JBrowse link
G Lipt1 lipoyltransferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LIPT1 mRNA CTD PMID:24690739 NCBI chr 9:40,107,938...40,118,268
Ensembl chr 9:40,098,615...40,113,565 		JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LMCD1 mRNA CTD PMID:24690739 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046 		JBrowse link
G Lmtk2 lemur tyrosine kinase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LMTK2 mRNA CTD PMID:24690739 NCBI chr12:10,426,772...10,508,750
Ensembl chr12:10,426,777...10,508,750 		JBrowse link
G LOC100361693 zinc finger protein 53-like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF34 mRNA CTD PMID:24690739 NCBI chr 5:157,509,762...157,513,970
Ensembl chr 5:157,509,451...157,599,926 		JBrowse link
G LOC100910577 zinc finger protein 709-like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF77 mRNA CTD PMID:24690739 NCBI chr 7:7,269,879...7,316,286
Ensembl chr 7:7,269,927...7,286,051 		JBrowse link
G LOC685680 similar to TPA-induced transmembrane protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C3ORF52 mRNA CTD PMID:24690739 NCBI chr11:55,166,986...55,192,273
Ensembl chr11:55,166,678...55,192,292 		JBrowse link
G Loricrin loricrin cornified envelope precursor protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LORICRIN mRNA CTD PMID:24690739 NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807 		JBrowse link
G Lratd2 LRAT domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LRATD2 mRNA CTD PMID:24690739 NCBI chr 7:92,376,713...92,387,045
Ensembl chr 7:92,362,194...92,388,189 		JBrowse link
G Lrp8 LDL receptor related protein 8 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LRP8 mRNA CTD PMID:24690739 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352 		JBrowse link
G Lsmem1 leucine-rich single-pass membrane protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LSMEM1 mRNA CTD PMID:24690739 NCBI chr 6:57,250,221...57,262,240
Ensembl chr 6:57,252,056...57,261,653 		JBrowse link
G Ltb4r leukotriene B4 receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LTB4R mRNA CTD PMID:24690739 NCBI chr15:29,263,126...29,265,716 JBrowse link
G Luc7l3 LUC7-like 3 pre-mRNA splicing factor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CROP mRNA CTD PMID:24690739 NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MACF1 mRNA CTD PMID:24690739 NCBI chr 5:135,623,729...135,949,097
Ensembl chr 5:135,623,742...135,945,905 		JBrowse link
G Mad2l1bp MAD2L1 binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAD2L1BP mRNA CTD PMID:24690739 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447 		JBrowse link
G Mafb MAF bZIP transcription factor B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAFB mRNA CTD PMID:24690739 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031 		JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Disulfiram results in increased expression of MAFF mRNA CTD PMID:20566472 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851 		JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Disulfiram results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026 		JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO Disulfiram results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048 		JBrowse link
G Magoh mago homolog, exon junction complex subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAGOH mRNA CTD PMID:24690739 NCBI chr 5:122,639,268...122,646,650
Ensembl chr 5:122,639,308...122,646,617 		JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MAN1B1 mRNA CTD PMID:24690739 NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006 		JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAOA mRNA CTD PMID:24690739 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP1LC3B mRNA CTD PMID:24690739 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP2K3 mRNA CTD PMID:24690739 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492 		JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP3K13 mRNA CTD PMID:24690739 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MAP3K20 mRNA CTD PMID:24690739 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased phosphorylation of MAPK1 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK1 protein CTD PMID:23033007 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Copper co-treated with Disulfiram co-treated with Gemcitabine] results in increased phosphorylation of MAPK3 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK3 protein CTD PMID:23033007 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP
ISO		 [Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]
[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein		 CTD PMID:11239917 PMID:24690739 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK9 protein CTD PMID:24690739 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAPRE2 mRNA CTD PMID:24690739 NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044 		JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions
decreases expression		 ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] CTD PMID:19789329 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions
decreases expression		 ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] CTD PMID:19789329 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Me1 malic enzyme 1 increases expression ISO Disulfiram results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304 		JBrowse link
G Mfsd3 major facilitator superfamily domain containing 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MFSD3 mRNA CTD PMID:24690739 NCBI chr 7:108,419,644...108,423,469
Ensembl chr 7:108,421,350...108,423,461 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase decreases activity
multiple interactions
increases degradation		 EXP
ISO		 Disulfiram results in decreased activity of MGMT protein
[Disulfiram binds to Copper] which results in decreased expression of and results in decreased activity of MGMT protein; [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein; bortezomib inhibits the reaction [Disulfiram results in increased degradation of MGMT protein]; Disulfiram inhibits the reaction [O(6)-benzylguanine binds to MGMT protein]; Disulfiram results in decreased expression of and results in decreased activity of MGMT protein		 CTD PMID:24193513 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Disulfiram results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Midn midnolin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MIDN mRNA CTD PMID:24690739 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752 		JBrowse link
G Mix23 mitochondrial matrix import factor 23 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MIX23 mRNA CTD PMID:24690739 NCBI chr11:64,660,711...64,681,000
Ensembl chr11:64,660,711...64,681,000 		JBrowse link
G Mmp10 matrix metallopeptidase 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MMP10 mRNA CTD PMID:24690739 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Disulfiram results in decreased expression of MMP2 CTD PMID:18047805 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MMP3 mRNA CTD PMID:24690739 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Disulfiram results in decreased expression of MMP9 CTD PMID:18047805 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mppe1 metallophosphoesterase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MPPE1 mRNA CTD PMID:24690739 NCBI chr18:60,763,418...60,781,553
Ensembl chr18:60,763,419...60,781,553 		JBrowse link
G Mrpl10 mitochondrial ribosomal protein L10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL10 mRNA CTD PMID:24690739 NCBI chr10:82,026,031...82,034,451
Ensembl chr10:82,026,031...82,034,443 		JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL18 mRNA CTD PMID:24690739 NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987 		JBrowse link
G Mrpl45 mitochondrial ribosomal protein L45 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL45 mRNA CTD PMID:24690739 NCBI chr10:82,308,650...82,320,474
Ensembl chr10:82,308,427...82,320,474 		JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I affects activity
affects expression		 EXP Disulfiram affects the activity of COX1 protein
Disulfiram affects the expression of COX1 mRNA		 CTD PMID:17936468 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867 		JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MT1A mRNA CTD PMID:24690739 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 		JBrowse link
G Mt2A metallothionein 2A increases expression
multiple interactions		 ISO Disulfiram results in increased expression of MT2A mRNA
cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA]		 CTD PMID:19789329 PMID:32661532 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mt3 metallothionein 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MT3 mRNA CTD PMID:24690739 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158 		JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MTF1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT1M mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA] CTD PMID:24690739 PMID:32661532 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136 		JBrowse link
G Mx1 MX dynamin like GTPase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MX1 mRNA CTD PMID:24690739 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507 		JBrowse link
G Mylip myosin regulatory light chain interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MYLIP mRNA CTD PMID:24690739 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295 		JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MYLK mRNA CTD PMID:24690739 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261 		JBrowse link
G Nat14 N-acetyltransferase 14 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NAT14 mRNA CTD PMID:24690739 NCBI chr 1:68,910,599...68,913,452
Ensembl chr 1:68,910,601...68,912,733 		JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCEH1 mRNA CTD PMID:24690739 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588 		JBrowse link
G Ncoa7 nuclear receptor coactivator 7 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCOA7 mRNA CTD PMID:24690739 NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871 		JBrowse link
G Ncstn nicastrin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCSTN mRNA CTD PMID:24690739 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454 		JBrowse link
G Nefh neurofilament heavy chain multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NEFH mRNA CTD PMID:24690739 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nfe2l3 NFE2 like bZIP transcription factor 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NFE2L3 mRNA CTD PMID:24690739 NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NFKB1 mRNA CTD PMID:24690739 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha decreases degradation
multiple interactions		 EXP
ISO		 Disulfiram results in decreased degradation of NFKBIA protein
[Disulfiram binds to Copper] which results in increased expression of NFKBIA protein		 CTD PMID:10418820 PMID:24690739 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NFKBIB protein CTD PMID:24690739 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862 		JBrowse link
G Ngdn neuroguidin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NGDN mRNA CTD PMID:24690739 NCBI chr15:28,489,950...28,497,286
Ensembl chr15:28,490,040...28,519,654 		JBrowse link
G Niban1 niban apoptosis regulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NIBAN1 mRNA CTD PMID:24690739 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729 		JBrowse link
G Nol12 nucleolar protein 12 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NOL12 mRNA CTD PMID:24690739 NCBI chr 7:110,493,294...110,498,908
Ensembl chr 7:110,493,246...110,498,907 		JBrowse link
G Nos2 nitric oxide synthase 2 affects expression EXP Disulfiram affects the expression of NOS2 mRNA CTD PMID:17936468 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nosip nitric oxide synthase interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NOSIP mRNA CTD PMID:24690739 NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650 		JBrowse link
G Npepl1 aminopeptidase-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NPEPL1 mRNA CTD PMID:24690739 NCBI chr 3:162,893,891...162,906,492
Ensembl chr 3:162,893,943...162,906,492 		JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NPPB mRNA CTD PMID:24690739 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nptx2 neuronal pentraxin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NPTX2 mRNA CTD PMID:24690739 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
increases activity		 ISO
EXP		 Disulfiram results in increased expression of NQO1 mRNA
Disulfiram results in increased activity of NQO1 protein		 CTD PMID:16045903 PMID:20566472 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Disulfiram binds to and affects the activity of NR1I2 protein
Disulfiram binds to and results in increased activity of NR1I2 protein		 CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NRARP mRNA CTD PMID:24690739 NCBI chr 3:7,992,582...7,995,136
Ensembl chr 3:7,992,552...7,995,133 		JBrowse link
G Nras NRAS proto-oncogene, GTPase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NRAS mRNA CTD PMID:24690739 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626 		JBrowse link
G Nrp1 neuropilin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NRP1 mRNA CTD PMID:24690739 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NT5E mRNA CTD PMID:24690739 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Nubp1 NUBP iron-sulfur cluster assembly factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NUBP1 mRNA CTD PMID:24690739 NCBI chr10:5,260,237...5,270,835 JBrowse link
G Nxf1 nuclear RNA export factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NXF1 mRNA CTD PMID:24690739 NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636 		JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NXT2 mRNA CTD PMID:24690739 NCBI chr  X:105,855,616...105,862,902
Ensembl chr  X:105,855,608...105,862,899 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of OASL mRNA CTD PMID:24690739 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Osmr oncostatin M receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of OSMR mRNA CTD PMID:24690739 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262 		JBrowse link
G P3h3 prolyl 3-hydroxylase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of P3H3 mRNA CTD PMID:24690739 NCBI chr 4:157,646,238...157,662,035
Ensembl chr 4:157,646,243...157,695,509 		JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of P3H4 mRNA CTD PMID:24690739 NCBI chr10:85,338,158...85,345,108
Ensembl chr10:85,338,161...85,345,093 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase increases activity EXP Disulfiram results in increased activity of PAM protein CTD PMID:8246921 PMID:10347250 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage		 ISO [Copper co-treated with Disulfiram] results in increased cleavage of PARP1 protein; [Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein; [Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein]
Disulfiram results in increased cleavage of PARP1 protein		 CTD PMID:17079463 PMID:19789329 PMID:23033007 PMID:24193513 PMID:24690739 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PCK2 mRNA CTD PMID:24690739 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pcnx4 pecanex 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PCNX4 mRNA CTD PMID:24690739 NCBI chr 6:91,125,063...91,170,423
Ensembl chr 6:91,125,063...91,170,439 		JBrowse link
G Pde5a phosphodiesterase 5A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDE5A mRNA CTD PMID:24690739 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDGFRB mRNA CTD PMID:24690739 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDLIM5 mRNA CTD PMID:24690739 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pdpn podoplanin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDPN protein
[Disulfiram binds to Copper] which results in increased expression of and results in increased phosphorylation of and results in increased ubiquitination of PDPN protein		 CTD PMID:24690739 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656 		JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PDRG1 mRNA CTD PMID:24690739 NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858
Ensembl chr 3:141,476,501...141,483,858 		JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Disulfiram results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PHLDA2 mRNA CTD PMID:24690739 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836 		JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PHLDB2 mRNA CTD PMID:24690739 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467 		JBrowse link
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PIGQ mRNA CTD PMID:24690739 NCBI chr10:14,942,571...14,958,584
Ensembl chr10:14,942,577...14,958,584 		JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PIK3IP1 mRNA CTD PMID:24690739 NCBI chr14:78,203,539...78,216,616
Ensembl chr14:78,204,053...78,216,608 		JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PIP4K2A mRNA CTD PMID:24690739 NCBI chr17:81,496,669...81,668,180
Ensembl chr17:81,496,670...81,668,029 		JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLOD2 mRNA CTD PMID:24690739 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255 		JBrowse link
G Plpbp pyridoxal phosphate binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PLPBP mRNA CTD PMID:24690739 NCBI chr16:65,003,292...65,014,886
Ensembl chr16:65,002,223...65,014,886 		JBrowse link
G Plscr4 phospholipid scramblase 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLSCR4 mRNA CTD PMID:24690739 NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:92,987,381...93,026,049 		JBrowse link
G Plxnb2 plexin B2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLXNB2 mRNA CTD PMID:24690739 NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330 		JBrowse link
G Pnldc1 PARN like ribonuclease domain containing exonuclease 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PNLDC1 mRNA CTD PMID:24690739 NCBI chr 1:47,843,224...47,861,675
Ensembl chr 1:47,843,224...47,861,674 		JBrowse link
G Pnma2 PNMA family member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PNMA2 mRNA CTD PMID:24690739 NCBI chr15:41,111,942...41,119,649
Ensembl chr15:41,112,009...41,121,427 		JBrowse link
G Polr2c RNA polymerase II subunit C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POLR2C mRNA CTD PMID:24690739 NCBI chr19:10,158,153...10,164,935
Ensembl chr19:10,157,823...10,164,945 		JBrowse link
G Polr2m RNA polymerase II subunit M multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POLR2M mRNA CTD PMID:24690739 NCBI chr 8:72,131,992...72,139,423
Ensembl chr 8:72,131,530...72,243,036 		JBrowse link
G Pomc proopiomelanocortin decreases expression EXP Disulfiram results in decreased expression of POMC protein alternative form CTD PMID:8246921 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Pop4 POP4 homolog, ribonuclease P/MRP subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POP4 mRNA CTD PMID:24690739 NCBI chr 1:90,960,026...90,968,360
Ensembl chr 1:90,960,022...90,968,443 		JBrowse link
G Postn periostin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of POSTN mRNA CTD PMID:24690739 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
affects expression		 ISO Disulfiram binds to and results in increased activity of PPARG protein
Disulfiram affects the expression of PPARG mRNA		 CTD PMID:32712770 PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPIA mRNA CTD PMID:24690739 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP1R15A mRNA CTD PMID:24690739 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP1R3C mRNA CTD PMID:24690739 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961 		JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP2R2B mRNA CTD PMID:24690739 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025 		JBrowse link
G Prok2 prokineticin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PROK2 mRNA CTD PMID:24690739 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385 		JBrowse link
G Prss8 serine protease 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PRSS8 mRNA CTD PMID:24690739 NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815 		JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PSAT1 mRNA CTD PMID:24690739 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PSMC4 mRNA CTD PMID:24690739 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494 		JBrowse link
G Pspn persephin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PSPN mRNA CTD PMID:24690739 NCBI chr 9:1,841,105...1,841,663
Ensembl chr 9:1,840,896...1,854,327 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO [Copper co-treated with Disulfiram] results in decreased expression of PTEN protein CTD PMID:20424113 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PTGES3 mRNA CTD PMID:24690739 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO Disulfiram results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP Disulfiram results in decreased expression of PTGS2 mRNA CTD PMID:10418820 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptma prothymosin alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PTMA mRNA CTD PMID:24690739 NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333 		JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PTX3 mRNA CTD PMID:24690739 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Rab5c RAB5C, member RAS oncogene family multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAB5C mRNA CTD PMID:24690739 NCBI chr10:85,642,553...85,666,142
Ensembl chr10:85,642,809...85,666,103 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAC1 mRNA CTD PMID:24690739 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rai2 retinoic acid induced 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAI2 mRNA CTD PMID:24690739 NCBI chr  X:32,948,656...33,011,222
Ensembl chr  X:32,948,656...33,011,264 		JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAMAC mRNA CTD PMID:24690739 NCBI chr 1:135,708,529...135,714,417
Ensembl chr 1:135,708,535...135,722,151 		JBrowse link
G Rasa1 RAS p21 protein activator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RASA1 mRNA CTD PMID:24690739 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854 		JBrowse link
G Rasd1 ras related dexamethasone induced 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RASD1 mRNA CTD PMID:24690739 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186 		JBrowse link
G Rasl11b RAS-like family 11 member B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RASL11B mRNA CTD PMID:24690739 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152 		JBrowse link
G Rbis ribosomal biogenesis factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBIS mRNA CTD PMID:24690739 NCBI chr 2:86,981,314...86,997,352
Ensembl chr 2:86,991,315...87,041,339 		JBrowse link
G Rbm18 RNA binding motif protein 18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBM18 mRNA CTD PMID:24690739 NCBI chr 3:19,467,333...19,487,171
Ensembl chr 3:19,467,335...19,487,178 		JBrowse link
G Rbm48 RNA binding motif protein 48 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBM48 mRNA CTD PMID:24690739 NCBI chr 4:30,559,063...30,569,409
Ensembl chr 4:30,559,087...30,569,406 		JBrowse link
G Rep15 RAB15 effector protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of REP15 mRNA CTD PMID:24690739 NCBI chr 4:179,951,935...179,953,008
Ensembl chr 4:179,951,935...179,953,008 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RFTN1 mRNA CTD PMID:24690739 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Rftn2 raftlin family member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RFTN2 mRNA CTD PMID:24690739 NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810 		JBrowse link
G Rgcc regulator of cell cycle multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGCC mRNA CTD PMID:24690739 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G RGD1306746 similar to Hypothetical protein MGC25529 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C2ORF42 mRNA CTD PMID:24690739 NCBI chr 4:118,887,688...118,916,808
Ensembl chr 4:118,888,112...118,916,936 		JBrowse link
G RGD1310553 similar to expressed sequence AI597479 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C2ORF49 mRNA CTD PMID:24690739 NCBI chr 9:45,371,396...45,382,123
Ensembl chr 9:45,371,430...45,382,120 		JBrowse link
G RGD1564664 similar to LOC387763 protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C11ORF96 mRNA CTD PMID:24690739 NCBI chr 3:79,920,131...79,921,523
Ensembl chr 3:79,920,129...79,921,523 		JBrowse link
G Rgs11 regulator of G-protein signaling 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RGS11 mRNA CTD PMID:24690739 NCBI chr10:15,222,803...15,231,060
Ensembl chr10:15,222,803...15,231,060 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGS16 mRNA CTD PMID:24690739 NCBI chr13:65,887,788...65,891,232
Ensembl chr13:65,887,530...65,892,857 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGS2 mRNA CTD PMID:24690739 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RHBDF1 mRNA CTD PMID:24690739 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763 		JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RHBDF2 mRNA CTD PMID:24690739 NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283 		JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RHOB mRNA CTD PMID:24690739 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
G Rnf207 ring finger protein 207 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RNF207 mRNA CTD PMID:24690739 NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375 		JBrowse link
G Rpl23 ribosomal protein L23 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL23 mRNA CTD PMID:24690739 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870 		JBrowse link
G Rpl29 ribosomal protein L29 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL29 mRNA CTD PMID:24690739 NCBI chr 8:107,068,929...107,070,963
Ensembl chr 8:107,068,480...107,070,914 		JBrowse link
G Rpl38 ribosomal protein L38 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL38 mRNA CTD PMID:24690739 NCBI chr10:99,701,330...99,705,004
Ensembl chr10:99,701,362...99,705,004 		JBrowse link
G Rps15 ribosomal protein S15 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPS15 mRNA CTD PMID:24690739 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450 		JBrowse link
G Rps7 ribosomal protein S7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPS7 mRNA CTD PMID:24690739 NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RRAD mRNA CTD PMID:24690739 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417 		JBrowse link
G Rragd Ras-related GTP binding D multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RRAGD mRNA CTD PMID:24690739 NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356 		JBrowse link
G Rras RAS related multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RRAS mRNA CTD PMID:24690739 NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RSAD2 mRNA CTD PMID:24690739 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G RT1-CE5 RT1 class I, locus CE5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HLA-F mRNA CTD PMID:24690739 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP Disulfiram results in increased expression of RUNX2 mRNA CTD PMID:24496638 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167 		JBrowse link
G Rybp RING1 and YY1 binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RYBP mRNA CTD PMID:24690739 NCBI chr 4:132,876,361...132,927,580
NCBI chr 4:132,876,260...132,929,075
Ensembl chr 4:132,876,361...132,928,316 		JBrowse link
G Sap18 Sin3A associated protein 18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAP18 mRNA CTD PMID:24690739 NCBI chr15:31,943,228...31,947,534
Ensembl chr15:31,943,230...31,950,038 		JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAR1B mRNA CTD PMID:24690739 NCBI chr10:36,024,443...36,054,067
Ensembl chr10:36,024,382...36,054,066 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAT1 mRNA CTD PMID:24690739 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813 		JBrowse link
G Sbds Sbds, ribosome maturation factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SBDS mRNA CTD PMID:24690739 NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649 		JBrowse link
G Scarf2 scavenger receptor class F, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SCARF2 mRNA CTD PMID:24690739 NCBI chr11:83,175,956...83,187,415
Ensembl chr11:83,175,963...83,187,348 		JBrowse link
G Sec61b SEC61 translocon subunit beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SEC61B mRNA CTD PMID:24690739 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804 		JBrowse link
G Sel1l3 SEL1L family member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SEL1L3 mRNA CTD PMID:24690739 NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644 		JBrowse link
G Sem1 SEM1 26S proteasome subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SEM1 mRNA CTD PMID:24690739 NCBI chr 4:34,671,848...34,692,005
Ensembl chr 4:34,671,848...34,692,005 		JBrowse link
G Sertad1 SERTA domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SERTAD1 mRNA CTD PMID:24690739 NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SF3B4 mRNA CTD PMID:24690739 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959 		JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SGTA mRNA CTD PMID:24690739 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458 		JBrowse link
G Sh3pxd2a SH3 and PX domains 2A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SH3PXD2A mRNA CTD PMID:24690739 NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166 		JBrowse link
G Sik1 salt-inducible kinase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIK1 mRNA CTD PMID:24690739 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIRT1 mRNA CTD PMID:24690739 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt6 sirtuin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIRT6 mRNA CTD PMID:24690739 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914 		JBrowse link
G Ski Ski proto-oncogene multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SKI mRNA CTD PMID:24690739 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733 		JBrowse link
G Skil SKI-like proto-oncogene multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SKIL mRNA CTD PMID:24690739 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080 		JBrowse link
G Slc16a10 solute carrier family 16 member 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC16A10 mRNA CTD PMID:24690739 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839 		JBrowse link
G Slc25a37 solute carrier family 25 member 37 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC25A37 mRNA CTD PMID:24690739 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199 		JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC30A1 mRNA CTD PMID:24690739 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910 		JBrowse link
G Slc44a1 solute carrier family 44 member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC44A1 mRNA CTD PMID:24690739 NCBI chr 5:68,061,941...68,241,912
Ensembl chr 5:68,063,618...68,241,909 		JBrowse link
G Slc44a2 solute carrier family 44 member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC44A2 mRNA CTD PMID:24690739 NCBI chr 8:19,870,867...19,905,345
Ensembl chr 8:19,870,888...19,905,342 		JBrowse link
G Slc6a9 solute carrier family 6 member 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC6A9 mRNA CTD PMID:24690739 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC7A1 mRNA CTD PMID:24690739 NCBI chr12:6,628,214...6,703,849
Ensembl chr12:6,628,007...6,703,849 		JBrowse link
G Slc7a6os solute carrier family 7, member 6 opposite strand multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC7A6OS mRNA CTD PMID:24690739 NCBI chr19:34,101,978...34,110,666
Ensembl chr19:34,101,982...34,110,651 		JBrowse link
G Slfn13 schlafen family member 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLFN11 mRNA CTD PMID:24690739 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383 		JBrowse link
G Slu7 SLU7 homolog, splicing factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLU7 mRNA CTD PMID:24690739 NCBI chr10:27,908,325...27,923,784
Ensembl chr10:27,908,396...27,923,349 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SMAD3 mRNA CTD PMID:24690739 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smox spermine oxidase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SMOX mRNA CTD PMID:24690739 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNAI1 mRNA CTD PMID:24690739 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snip1 Smad nuclear interacting protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNIP1 mRNA CTD PMID:24690739 NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845 		JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNRPB2 mRNA CTD PMID:24690739 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases activity		 ISO Disulfiram results in increased expression of SOD1 mRNA
Disulfiram results in decreased activity of SOD1 protein		 CTD PMID:19016906 PMID:20566472 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions		 ISO Disulfiram results in increased expression of SOD2 mRNA
[Disulfiram co-treated with Zinc Sulfate] results in increased expression of SOD2 mRNA		 CTD PMID:20566472 PMID:32712770 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 increases expression ISO Disulfiram results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sox8 SRY-box transcription factor 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SOX8 mRNA CTD PMID:24690739 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818 		JBrowse link
G Spacdr sperm acrosome developmental regulator multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SPACDR mRNA CTD PMID:24690739 NCBI chr12:18,930,608...18,936,787
Ensembl chr12:18,914,398...18,952,008 		JBrowse link
G Spata20 spermatogenesis associated 20 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPATA20 mRNA CTD PMID:24690739 NCBI chr10:79,427,525...79,435,472
Ensembl chr10:79,427,528...79,434,368 		JBrowse link
G Spire1 spire-type actin nucleation factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPIRE1 mRNA CTD PMID:24690739 NCBI chr18:61,041,290...61,171,670
Ensembl chr18:61,041,290...61,171,899 		JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Disulfiram results in increased expression of SPSB1 mRNA CTD PMID:20566472 NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468 		JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPTBN1 mRNA CTD PMID:24690739 NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507 		JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SPTY2D1 mRNA CTD PMID:24690739 NCBI chr 1:97,531,495...97,549,633
Ensembl chr 1:97,531,508...97,549,581 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA CTD PMID:24690739 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Disulfiram results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Stc2 stanniocalcin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of STC2 mRNA CTD PMID:24690739 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Steep1 STING1 ER exit protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of STEEP1 mRNA CTD PMID:24690739 NCBI chr  X:116,087,626...116,114,159
Ensembl chr  X:116,060,929...116,114,159 		JBrowse link
G Stx3 syntaxin 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of STX3 mRNA CTD PMID:24690739 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805 		JBrowse link
G Sulf1 sulfatase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SULF1 mRNA; [Disulfiram binds to Copper] which results in increased expression of SULF1 protein CTD PMID:24690739 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584 		JBrowse link
G Sumo2 small ubiquitin-like modifier 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SUMO2 mRNA CTD PMID:24690739 NCBI chr10:100,771,941...100,784,503
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SUN1 mRNA CTD PMID:24690739 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571 		JBrowse link
G Sun2 Sad1 and UNC84 domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SUN2 mRNA CTD PMID:24690739 NCBI chr 7:111,275,374...111,292,565
Ensembl chr 7:111,275,380...111,292,553 		JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SUPT4H1 mRNA CTD PMID:24690739 NCBI chr10:72,539,323...72,545,582
Ensembl chr10:72,539,382...72,545,831 		JBrowse link
G Synj1 synaptojanin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SYNJ1 mRNA CTD PMID:24690739 NCBI chr11:30,192,629...30,269,277
Ensembl chr11:30,192,629...30,269,220 		JBrowse link
G Szrd1 SUZ RNA binding domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SZRD1 mRNA CTD PMID:24690739 NCBI chr 5:153,418,748...153,443,286
Ensembl chr 5:153,418,748...153,443,252 		JBrowse link
G Taf13 TATA-box binding protein associated factor 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAF13 mRNA CTD PMID:24690739 NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878 		JBrowse link
G Taf7 TATA-box binding protein associated factor 7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAF7 mRNA CTD PMID:24690739 NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134 		JBrowse link
G Tamalin trafficking regulator and scaffold protein tamalin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAMALIN mRNA CTD PMID:24690739 NCBI chr 7:132,338,900...132,359,519
Ensembl chr 7:132,338,900...132,346,666 		JBrowse link
G Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TANC1 mRNA CTD PMID:24690739 NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:44,134,016...44,331,627 		JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAP2 mRNA CTD PMID:24690739 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407 		JBrowse link
G Tapbp TAP binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TAPBP mRNA CTD PMID:24690739 NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181 		JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [Ethanol co-treated with Disulfiram] results in increased activity of TAT protein CTD PMID:9591243 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031 		JBrowse link
G Tcea2 transcription elongation factor A2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TCEA2 mRNA CTD PMID:24690739 NCBI chr 3:168,796,244...168,804,125
Ensembl chr 3:168,796,331...168,804,116 		JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TCP1 mRNA CTD PMID:24690739 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Tent5b terminal nucleotidyltransferase 5B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TENT5B mRNA CTD PMID:24690739 NCBI chr 5:145,695,358...145,702,668
Ensembl chr 5:145,695,362...145,706,073 		JBrowse link
G Tent5c terminal nucleotidyltransferase 5C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TENT5C mRNA CTD PMID:24690739 NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744 		JBrowse link
G Tfip11 tuftelin interacting protein 11 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TFIP11 mRNA CTD PMID:24690739 NCBI chr12:44,299,619...44,311,851
Ensembl chr12:44,299,622...44,311,855 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO Disulfiram results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Thap1 THAP domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of THAP1 mRNA CTD PMID:24690739 NCBI chr16:65,905,348...65,909,942
Ensembl chr16:65,904,230...65,909,942 		JBrowse link
G Them6 thioesterase superfamily member 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of THEM6 mRNA CTD PMID:24690739 NCBI chr 7:106,606,570...106,609,747
Ensembl chr 7:106,606,570...106,609,746 		JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Disulfiram binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Ticam2 TIR domain containing adaptor molecule 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TICAM2 mRNA CTD PMID:24690739 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462 		JBrowse link
G Tmem167a transmembrane protein 167A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TMEM167A mRNA CTD PMID:24690739 NCBI chr 2:21,197,728...21,216,746
Ensembl chr 2:21,197,786...21,212,099 		JBrowse link
G Tmem175 transmembrane protein 175 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM175 mRNA CTD PMID:24690739 NCBI chr14:1,073,410...1,089,764
Ensembl chr14:1,073,523...1,089,819 		JBrowse link
G Tmem208 transmembrane protein 208 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TMEM208 mRNA CTD PMID:24690739 NCBI chr19:33,203,587...33,206,287
Ensembl chr19:33,203,587...33,212,183 		JBrowse link
G Tmem35b transmembrane protein 35B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM35B mRNA CTD PMID:24690739 NCBI chr 5:139,446,317...139,449,947
Ensembl chr 5:139,444,399...139,449,947 		JBrowse link
G Tmem42 transmembrane protein 42 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM42 mRNA CTD PMID:24690739 NCBI chr 8:122,674,793...122,677,290
Ensembl chr 8:122,674,070...122,677,276 		JBrowse link
G Tmem43 transmembrane protein 43 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM43 mRNA CTD PMID:24690739 NCBI chr 4:123,977,680...123,992,823
Ensembl chr 4:123,977,625...123,992,825 		JBrowse link
G Tmem44 transmembrane protein 44 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM44 mRNA CTD PMID:24690739 NCBI chr11:70,181,120...70,216,958
Ensembl chr11:70,181,345...70,216,958 		JBrowse link
G Tnf tumor necrosis factor decreases expression
increases secretion
multiple interactions		 EXP
ISO		 Disulfiram results in decreased expression of TNF mRNA
Disulfiram results in increased secretion of TNF protein
[Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of TNF protein]; Disulfiram promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein]		 CTD PMID:10418820 PMID: