Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:organic disulfide
go back to main search page
Accession:CHEBI:35489 term browser browse the term
Definition:Compounds of structure RSSR in which R and R' are organic groups.
Synonyms:exact_synonym: disulfides
 related_synonym: Formula=S2R2;   SMILES=[*]SS[*];   an organic disulfide;   organic disulfides



show annotations for term's descendants           Sort by:
 
2,2'-dithiodiethanol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 affects response to substance ISO TP53 protein affects the susceptibility to 2-hydroxyethyl disulfide CTD PMID:22926048 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 multiple interactions ISO [2-hydroxyethyl disulfide co-treated with Glucose deficiency] results in decreased activity of [XRCC5 protein binds to XRCC6 protein] CTD PMID:22926048 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Xrcc6 X-ray repair cross complementing 6 multiple interactions ISO [2-hydroxyethyl disulfide co-treated with Glucose deficiency] results in decreased activity of [XRCC5 protein binds to XRCC6 protein] CTD PMID:22926048 NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762
JBrowse link
4,4'-dipyridyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions ISO 4,4'-dipyridyl disulfide inhibits the reaction [5,5'-bis(8-(phenylamino)-1-naphthalenesulfonate) binds to KEAP1 protein]; 4,4'-dipyridyl disulfide promotes the reaction [4-(2-pyridylazo)resorcinol inhibits the reaction [Zinc binds to KEAP1 protein]] CTD PMID:15865434 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase affects binding ISO 4,4'-dipyridyl disulfide binds to MGMT protein CTD PMID:12974631 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
aldrithiol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Casp3 caspase 3 increases activity EXP 2,2'-dipyridyl disulfide results in increased activity of CASP3 protein CTD PMID:11331359 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp9 caspase 9 increases activity EXP 2,2'-dipyridyl disulfide results in increased activity of CASP9 protein CTD PMID:11331359 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP 2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK1 protein; N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK1 protein]; phenyl-N-tert-butylnitrone inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:11331359 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP 2,2'-dipyridyl disulfide results in increased phosphorylation of and results in increased activity of MAPK3 protein CTD PMID:11331359 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nppa natriuretic peptide A multiple interactions
increases expression
EXP polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased expression of NPPA protein] CTD PMID:25449040 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
JBrowse link
G Ppp1r12a protein phosphatase 1, regulatory subunit 12A increases phosphorylation
multiple interactions
EXP 2,2'-dipyridyl disulfide results in increased phosphorylation of PPP1R12A protein
polydatin inhibits the reaction [2,2'-dipyridyl disulfide results in increased phosphorylation of PPP1R12A protein]
CTD PMID:25449040 NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
JBrowse link
allyl methyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
multiple interactions
ISO allyl methyl disulfide results in decreased activity of CYP3A4 protein
allyl methyl disulfide inhibits the reaction [CYP3A4 protein results in increased hydroxylation of Midazolam]
CTD PMID:18385293 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO allyl methyl disulfide inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:26969520 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Il6 interleukin 6 multiple interactions ISO allyl methyl disulfide inhibits the reaction [Acetaminophen results in increased expression of IL6 protein] CTD PMID:26969520 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ptprc protein tyrosine phosphatase, receptor type, C multiple interactions ISO allyl methyl disulfide inhibits the reaction [Acetaminophen results in increased expression of PTPRC protein] CTD PMID:26969520 NCBI chr13:49,596,193...49,708,283
Ensembl chr13:49,596,193...49,708,692
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO allyl methyl disulfide inhibits the reaction [Acetaminophen results in increased expression of TNF protein] CTD PMID:26969520 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
chetomin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Edn1 endothelin 1 multiple interactions ISO chetomin inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 mRNA]; chetomin inhibits the reaction [Oxygen deficiency results in increased expression of EDN1 protein] CTD PMID:21926265 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
decreases expression
ISO chetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]]; chetomin inhibits the reaction [HIF1A protein promotes the reaction [TNF protein results in decreased metabolism of Oxygen]]
chetomin results in decreased expression of HIF1A mRNA
CTD PMID:19744167 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO chetomin inhibits the reaction [HIF1A protein promotes the reaction [TNF protein results in decreased metabolism of Oxygen]] CTD PMID:19744167 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO chetomin inhibits the reaction [aristolochic acid I results in increased expression of VEGFA protein]; chetomin inhibits the reaction [HIF1A protein promotes the reaction [Lipopolysaccharides results in increased expression of VEGFA protein]] CTD PMID:19744167 PMID:21554934 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
cystamine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 mRNA]; Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of ACTA2 protein] CTD PMID:17708605 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of COL1A1 mRNA] CTD PMID:17708605 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 mRNA]; Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TGM2 protein] CTD PMID:17708605 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 multiple interactions EXP Cystamine inhibits the reaction [Carbon Tetrachloride results in increased expression of TIMP1 mRNA] CTD PMID:17708605 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
diallyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression ISO diallyl disulfide results in increased expression of ABCB1 mRNA CTD PMID:22397993 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases expression
increases expression
ISO diallyl disulfide results in decreased expression of ABCC1 mRNA
diallyl disulfide results in increased expression of ABCC1 mRNA
CTD PMID:22397993 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
affects expression
ISO diallyl disulfide results in increased expression of ABCC3 mRNA
diallyl disulfide affects the expression of ABCC3 mRNA
CTD PMID:22397993 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression
decreases expression
ISO diallyl disulfide results in increased expression of ABCC4 mRNA
diallyl disulfide results in decreased expression of ABCC4 mRNA
CTD PMID:22397993 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcc6 ATP binding cassette subfamily C member 6 decreases expression
increases expression
ISO diallyl disulfide results in decreased expression of ABCC6 mRNA
diallyl disulfide results in increased expression of ABCC6 mRNA
CTD PMID:22397993 NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO diallyl disulfide results in increased phosphorylation of AKT1 protein CTD PMID:23663050 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO diallyl disulfide results in increased expression of ATF3 protein CTD PMID:15897233 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO diallyl disulfide results in increased expression of BAX mRNA; diallyl disulfide results in increased expression of BAX protein CTD PMID:17647244 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression EXP
ISO
diallyl disulfide results in decreased expression of BCL2 protein
diallyl disulfide results in decreased expression of BCL2 mRNA; diallyl disulfide results in decreased expression of BCL2 protein
CTD PMID:14522920 PMID:16052692 PMID:17647244 PMID:30677442 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression ISO diallyl disulfide results in decreased expression of BDNF protein CTD PMID:23732363 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 decreases expression ISO diallyl disulfide results in decreased expression of BIRC3 protein CTD PMID:17647244 NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO diallyl disulfide results in decreased expression of BIRC5 protein CTD PMID:17647244 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
multiple interactions
ISO diallyl disulfide results in increased activity of CASP3 protein
diallyl disulfide results in increased cleavage of CASP3 protein
diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]
CTD PMID:14522920 PMID:17647244 PMID:30677442 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp4 caspase 4 increases activity ISO diallyl disulfide results in increased activity of CASP4 protein CTD PMID:17647244 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092
JBrowse link
G Casp8 caspase 8 multiple interactions
increases cleavage
ISO diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP8 protein]
diallyl disulfide results in increased cleavage of CASP8 protein
CTD PMID:30677442 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 increases activity
increases cleavage
multiple interactions
ISO diallyl disulfide results in increased activity of CASP9 protein
diallyl disulfide results in increased cleavage of CASP9 protein
diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP9 protein]
CTD PMID:14522920 PMID:17647244 PMID:30677442 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cast calpastatin decreases expression ISO diallyl disulfide results in decreased expression of CAST mRNA; diallyl disulfide results in decreased expression of CAST protein CTD PMID:17647244 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cat catalase multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein] CTD PMID:24293383 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO diallyl disulfide promotes the reaction [NOS3 protein binds to CAV1 protein] CTD PMID:20229525 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccnb1 cyclin B1 decreases expression
increases expression
ISO diallyl disulfide results in decreased expression of CCNB1 protein
diallyl disulfide results in increased expression of CCNB1 protein
CTD PMID:16691315 PMID:19202565 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
JBrowse link
G Ccnc cyclin C multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of CCNC mRNA CTD PMID:31077537 NCBI chr 5:35,266,828...35,284,943
Ensembl chr 5:35,266,823...35,296,584
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO diallyl disulfide results in decreased expression of CDH1 mRNA; diallyl disulfide results in decreased expression of CDH1 protein CTD PMID:20600798 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdhr1 cadherin-related family member 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of CDHR1 mRNA CTD PMID:31077537 NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO diallyl disulfide results in decreased expression of CDK1 protein CTD PMID:16691315 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdkal1 CDK5 regulatory subunit associated protein 1-like 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of CDKAL1 mRNA CTD PMID:31077537 NCBI chr17:34,718,680...34,769,614
Ensembl chr17:34,718,687...35,407,524
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of CDKN2B mRNA CTD PMID:31077537 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050
JBrowse link
G Cldn2 claudin 2 decreases expression ISO diallyl disulfide results in decreased expression of CLDN2 mRNA; diallyl disulfide results in decreased expression of CLDN2 protein CTD PMID:20600798 NCBI chr  X:103,459,870...103,473,794
Ensembl chr  X:103,459,780...103,474,838
JBrowse link
G Cldn3 claudin 3 decreases expression ISO diallyl disulfide results in decreased expression of CLDN3 mRNA; diallyl disulfide results in decreased expression of CLDN3 protein CTD PMID:20600798 NCBI chr12:21,708,538...21,710,010
Ensembl chr12:21,708,398...21,711,001
JBrowse link
G Cldn4 claudin 4 decreases expression ISO diallyl disulfide results in decreased expression of CLDN4 mRNA; diallyl disulfide results in decreased expression of CLDN4 protein CTD PMID:20600798 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Cldn5 claudin 5 decreases expression ISO diallyl disulfide results in decreased expression of CLDN5 mRNA; diallyl disulfide results in decreased expression of CLDN5 protein CTD PMID:20600798 NCBI chr11:82,212,822...82,214,248 JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases expression ISO diallyl disulfide results in decreased expression of CREB1 protein modified form CTD PMID:23732363 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Ctnnb1 catenin beta 1 increases expression
decreases phosphorylation
ISO diallyl disulfide results in increased expression of CTNNB1 mRNA; diallyl disulfide results in increased expression of CTNNB1 protein
diallyl disulfide results in decreased phosphorylation of CTNNB1 protein
CTD PMID:20600798 PMID:23663050 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
decreases activity
EXP
ISO
diallyl disulfide results in increased expression of CYP1A1 protein
diallyl disulfide results in decreased activity of CYP1A1 protein
CTD PMID:16000231 PMID:18339364 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP diallyl disulfide results in increased expression of CYP1A2 protein CTD PMID:16000231 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO diallyl disulfide results in increased expression of CYP2B1 mRNA; diallyl disulfide results in increased expression of CYP2B2 mRNA CTD PMID:17353348 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression
multiple interactions
decreases activity
ISO
EXP
diallyl disulfide results in decreased expression of CYP2E1 protein
diallyl disulfide inhibits the reaction [Ethanol results in increased expression of and results in increased activity of CYP2E1 protein]
diallyl disulfide results in decreased activity of CYP2E1 protein
[diallyl disulfide results in decreased expression of CYP2E1 protein] which results in decreased metabolism of and results in decreased susceptibility to Trichloroethylene
CTD PMID:10774820 PMID:16000231 PMID:18339364 PMID:19325051 PMID:24293383 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP diallyl disulfide results in increased expression of CYP3A2 protein CTD PMID:16000231 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dbr1 debranching RNA lariats 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of DBR1 mRNA CTD PMID:31077537 NCBI chr 8:100,139,039...100,150,768
Ensembl chr 8:100,139,034...100,151,030
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein decreases localization ISO diallyl disulfide results in decreased localization of DIABLO protein CTD PMID:17647244 NCBI chr12:33,055,784...33,070,400
Ensembl chr12:33,055,263...33,070,387
JBrowse link
G Dus2 dihydrouridine synthase 2 decreases expression
multiple interactions
EXP diallyl disulfide results in decreased expression of DUS2 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of DUS2 mRNA
CTD PMID:31077537 NCBI chr19:33,906,517...33,954,922
Ensembl chr19:33,911,750...33,954,709
JBrowse link
G Exo1 exonuclease 1 increases expression
multiple interactions
EXP diallyl disulfide results in increased expression of EXO1 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of EXO1 mRNA
CTD PMID:31077537 NCBI chr13:87,809,725...87,834,654
Ensembl chr13:87,809,810...87,834,654
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of FOSL1 mRNA CTD PMID:31077537 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of GCLC mRNA] CTD PMID:24293383 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression
multiple interactions
ISO diallyl disulfide results in increased expression of GDF15 protein
TP53 protein affects the reaction [diallyl disulfide results in increased expression of GDF15 protein]
CTD PMID:11925476 NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in increased activity of GPT protein] CTD PMID:24293383 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Grb2 growth factor receptor bound protein 2 affects expression
decreases expression
ISO diallyl disulfide affects the expression of GRB2 protein
diallyl disulfide results in decreased expression of GRB2 protein
CTD PMID:21695758 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309
JBrowse link
G Grhl1 grainyhead-like transcription factor 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of GRHL1 mRNA CTD PMID:31077537 NCBI chr 6:41,207,325...41,257,516
Ensembl chr 6:41,207,348...41,254,301
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation ISO diallyl disulfide results in increased phosphorylation of GSK3B protein CTD PMID:23663050 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased activity of GSR protein] CTD PMID:24293383 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of HES1 mRNA CTD PMID:31077537 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP [Carbon Tetrachloride co-treated with diallyl disulfide] results in increased expression of HMOX1 protein; diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of HMOX1 mRNA] CTD PMID:24293383 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression
multiple interactions
EXP diallyl disulfide results in increased expression of HSPA1A mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of HSPA1A mRNA
CTD PMID:31077537
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression
multiple interactions
EXP diallyl disulfide results in decreased expression of HSPH1 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of HSPH1 mRNA
CTD PMID:31077537 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein increases expression
multiple interactions
EXP diallyl disulfide results in increased expression of ID1 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of ID1 mRNA
CTD PMID:31077537 NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions
increases expression
EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of ID2 mRNA
diallyl disulfide results in increased expression of ID2 mRNA
CTD PMID:31077537 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of ID3 mRNA CTD PMID:31077537 NCBI chr 5:148,372,784...148,374,353
Ensembl chr 5:148,372,762...148,374,349
JBrowse link
G Itgb1bp1 integrin subunit beta 1 binding protein 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of ITGB1BP1 mRNA CTD PMID:31077537 NCBI chr 6:40,820,693...40,836,074
Ensembl chr 6:40,821,339...40,836,037
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases phosphorylation ISO diallyl disulfide results in increased phosphorylation of JUN protein CTD PMID:14522920 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression ISO diallyl disulfide results in increased expression of KIT protein CTD PMID:23663050 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Klf2 Kruppel-like factor 2 increases expression
multiple interactions
EXP diallyl disulfide results in increased expression of KLF2 mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of KLF2 mRNA
CTD PMID:31077537 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944
JBrowse link
G Malsu1 mitochondrial assembly of ribosomal large subunit 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of MALSU1 mRNA CTD PMID:31077537 NCBI chr 4:78,051,090...78,059,913
Ensembl chr 4:78,051,059...78,059,905
JBrowse link
G Map2k7 mitogen activated protein kinase kinase 7 affects expression ISO diallyl disulfide affects the expression of MAP2K7 protein CTD PMID:21695758 NCBI chr12:2,591,312...2,604,211
Ensembl chr12:2,591,219...2,604,222
JBrowse link
G Map3k3 mitogen activated protein kinase kinase kinase 3 affects expression ISO diallyl disulfide affects the expression of MAP3K3 protein CTD PMID:21695758 NCBI chr10:91,020,174...91,088,852
Ensembl chr10:91,020,174...91,088,848
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
decreases expression
multiple interactions
EXP
ISO
diallyl disulfide results in increased phosphorylation of MAPK1 protein
diallyl disulfide results in decreased expression of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl disulfide results in increased phosphorylation of MAPK1 protein]
CTD PMID:17263507 PMID:21695758 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
decreases expression
multiple interactions
EXP
ISO
diallyl disulfide results in increased phosphorylation of MAPK3 protein
diallyl disulfide results in decreased expression of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [diallyl disulfide results in increased phosphorylation of MAPK3 protein]
CTD PMID:17263507 PMID:21695758 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation
multiple interactions
ISO diallyl disulfide results in increased phosphorylation of MAPK8 protein
diallyl disulfide results in increased phosphorylation of and results in increased activity of MAPK8 protein
CTD PMID:14522920 PMID:17647244 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of MDM2 mRNA CTD PMID:31077537 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
decreases expression
ISO diallyl disulfide results in decreased expression of and results in decreased activity of MMP2 protein
diallyl disulfide results in decreased expression of MMP2 mRNA; diallyl disulfide results in decreased expression of MMP2 protein
CTD PMID:20600798 PMID:21695758 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO diallyl disulfide results in decreased expression of MMP7 protein CTD PMID:21695758 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
affects expression
decreases expression
ISO diallyl disulfide results in decreased expression of and results in decreased activity of MMP9 protein
diallyl disulfide affects the expression of MMP9 protein
diallyl disulfide results in decreased expression of MMP9 mRNA
CTD PMID:20600798 PMID:21695758 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mogs mannosyl-oligosaccharide glucosidase multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of MOGS mRNA CTD PMID:31077537 NCBI chr 4:115,621,623...115,625,026
Ensembl chr 4:115,621,623...115,625,032
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of and affects the localization of NFE2L2 protein] CTD PMID:24293383 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkbia NFKB inhibitor alpha increases phosphorylation
increases expression
multiple interactions
ISO
EXP
diallyl disulfide results in increased phosphorylation of NFKBIA protein
diallyl disulfide results in increased expression of NFKBIA mRNA
[Cadmium Chloride co-treated with diallyl disulfide] results in increased expression of NFKBIA mRNA
CTD PMID:23663050 PMID:31077537 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nos2 nitric oxide synthase 2 affects expression ISO diallyl disulfide affects the expression of NOS2 protein CTD PMID:21695758 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nos3 nitric oxide synthase 3 multiple interactions
increases expression
increases phosphorylation
decreases degradation
ISO diallyl disulfide promotes the reaction [NOS3 protein binds to CAV1 protein]; wortmannin inhibits the reaction [diallyl disulfide results in increased phosphorylation of NOS3 protein]
diallyl disulfide results in increased expression of NOS3 protein
diallyl disulfide results in decreased degradation of NOS3 protein
CTD PMID:20229525 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases activity
multiple interactions
EXP diallyl disulfide results in increased activity of NQO1 protein
diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 mRNA]; diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of NQO1 protein]
CTD PMID:8339252 PMID:24293383 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein] CTD PMID:30677442 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pmp22 peripheral myelin protein 22 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of PMP22 mRNA CTD PMID:31077537 NCBI chr10:47,795,709...47,825,715
Ensembl chr10:47,795,709...47,825,714
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of PPP3CA mRNA CTD PMID:31077537 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 affects expression ISO diallyl disulfide affects the expression of PTGS2 protein CTD PMID:21695758 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Sesn2 sestrin 2 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SESN2 mRNA CTD PMID:31077537 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
JBrowse link
G Sfn stratifin multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SFN mRNA CTD PMID:31077537 Ensembl chr 5:145,826,201...145,831,314 JBrowse link
G Snai1 snail family transcriptional repressor 1 decreases expression ISO diallyl disulfide results in decreased expression of SNAI1 mRNA; diallyl disulfide results in decreased expression of SNAI1 protein CTD PMID:20600798 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP diallyl disulfide inhibits the reaction [Carbon Tetrachloride results in decreased expression of SOD1 mRNA] CTD PMID:24293383 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Stag1 stromal antigen 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of STAG1 mRNA CTD PMID:31077537 NCBI chr 8:101,179,039...101,564,684
Ensembl chr 8:101,179,039...101,564,677
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of SUMO1 mRNA CTD PMID:31077537 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761
JBrowse link
G Tfdp2 transcription factor Dp-2 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TFDP2 mRNA CTD PMID:31077537 NCBI chr 8:96,760,459...96,901,466
Ensembl chr 8:96,760,504...96,896,682
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO diallyl disulfide results in increased expression of TIMP1 mRNA CTD PMID:20600798 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO diallyl disulfide results in increased expression of TIMP2 mRNA CTD PMID:20600798 NCBI chr10:103,541,199...103,590,611 JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP3 protein]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP8 protein]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of CASP9 protein]; diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein] CTD PMID:30677442 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases expression
ISO
EXP
Acetylcysteine inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]; Glutathione inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]; TP53 protein affects the reaction [diallyl disulfide results in increased expression of GDF15 protein]
[Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TP53 mRNA
CTD PMID:11925476 PMID:19202565 PMID:31077537 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tsg101 tumor susceptibility 101 multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of TSG101 mRNA CTD PMID:31077537 NCBI chr 1:97,412,689...97,442,589
Ensembl chr 1:97,410,848...97,442,554
JBrowse link
G Ube2h ubiquitin-conjugating enzyme E2H multiple interactions EXP [Cadmium Chloride co-treated with diallyl disulfide] results in decreased expression of UBE2H mRNA CTD PMID:31077537 NCBI chr 4:58,834,674...58,930,156
Ensembl chr 4:58,834,674...58,930,156
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases activity EXP diallyl disulfide results in increased activity of UGT1A1 protein CTD PMID:8339252 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO diallyl disulfide results in decreased expression of XIAP protein CTD PMID:17647244 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700
JBrowse link
dibenzothiazol-2-yl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ifng interferon gamma multiple interactions ISO [dibenzothiazyl disulfide co-treated with Sodium Dodecyl Sulfate] results in increased expression of IFNG protein CTD PMID:12062936 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il4 interleukin 4 multiple interactions ISO [dibenzothiazyl disulfide co-treated with Sodium Dodecyl Sulfate] results in increased expression of IL4 protein CTD PMID:12062936 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
dipropyl disulfide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity ISO n-propyl disulfide results in decreased activity of CYP1A1 protein CTD PMID:18339364 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO n-propyl disulfide results in decreased activity of CYP2E1 protein CTD PMID:18339364 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression EXP n-propyl disulfide results in increased expression of CYP3A2 protein CTD PMID:16000231 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
disulfiram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of AARS1 mRNA CTD PMID:24690739 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147
JBrowse link
G Abat 4-aminobutyrate aminotransferase multiple interactions EXP [Ethanol co-treated with Disulfiram] results in decreased activity of ABAT protein; [Ethanol co-treated with Disulfiram] results in decreased expression of ABAT mRNA CTD PMID:9591243 NCBI chr10:6,996,688...7,092,835
Ensembl chr10:6,999,819...7,092,835
JBrowse link
G Abca1 ATP binding cassette subfamily A member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCA1 mRNA CTD PMID:24690739 NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
JBrowse link
G Abca3 ATP binding cassette subfamily A member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCA3 mRNA CTD PMID:24690739 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity
multiple interactions
ISO Disulfiram results in decreased activity of ABCB11 protein
Disulfiram inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
CTD PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity
ISO Disulfiram affects the reaction [ABCB1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidopine binds to ABCB1 protein]; Disulfiram inhibits the reaction [azidoprazosin binds to ABCB1 protein]
Disulfiram metabolite results in decreased activity of ABCB1 protein; Disulfiram results in decreased activity of ABCB1 protein
CTD PMID:10841824 PMID:14978246 PMID:16028354 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases activity
multiple interactions
ISO Disulfiram results in decreased activity of ABCC1 protein
Disulfiram affects the reaction [ABCC1 protein results in increased hydrolysis of Adenosine Triphosphate]; Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC1 protein]
CTD PMID:14978246 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 multiple interactions ISO Disulfiram inhibits the reaction [8-azidoadenosine 5'-triphosphate binds to ABCC4 protein]; Disulfiram inhibits the reaction [ABCC4 protein results in increased hydrolysis of Adenosine Triphosphate] CTD PMID:14978246 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283
JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ABCG1 mRNA CTD PMID:24690739 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
JBrowse link
G Acad11 acyl-CoA dehydrogenase family, member 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACAD11 mRNA CTD PMID:24690739 NCBI chr 8:104,681,346...104,746,559
Ensembl chr 8:104,681,396...104,746,560
JBrowse link
G Ace2 angiotensin I converting enzyme 2 decreases expression ISO Disulfiram results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Ache acetylcholinesterase decreases expression EXP Disulfiram results in decreased expression of ACHE protein CTD PMID:3868355 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACSS2 mRNA CTD PMID:24690739 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675
JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ACTA2 mRNA CTD PMID:24690739 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADAM9 mRNA CTD PMID:24690739 NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ADAMTS1 mRNA CTD PMID:24690739 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103
JBrowse link
G Adarb1 adenosine deaminase, RNA-specific, B1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADARB1 mRNA CTD PMID:24690739 NCBI chr20:11,222,569...11,350,854
Ensembl chr20:11,222,583...11,350,852
JBrowse link
G Adcy3 adenylate cyclase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADCY3 mRNA CTD PMID:24690739 NCBI chr 6:27,100,089...27,203,686
Ensembl chr 6:27,124,828...27,203,686
JBrowse link
G Adgre5 adhesion G protein-coupled receptor E5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ADGRE5 mRNA CTD PMID:24690739 NCBI chr19:24,397,972...24,418,648
Ensembl chr19:24,398,689...24,418,638
JBrowse link
G Adh1 alcohol dehydrogenase 1 (class I) decreases activity EXP Disulfiram results in decreased activity of ADH1 protein CTD PMID:15551062 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Adm adrenomedullin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ADM mRNA CTD PMID:24690739 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
JBrowse link
G Afap1 actin filament associated protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of AFAP1 mRNA CTD PMID:24690739 NCBI chr14:74,743,322...74,856,295
Ensembl chr14:74,743,320...74,856,263
JBrowse link
G Agxt alanine--glyoxylate and serine--pyruvate aminotransferase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AGXT mRNA CTD PMID:24690739 NCBI chr 9:93,675,384...93,685,337
Ensembl chr 9:93,675,384...93,685,336
JBrowse link
G Agxt2 alanine-glyoxylate aminotransferase 2 multiple interactions EXP [Ethanol co-treated with Disulfiram] results in decreased activity of AGXT2 protein CTD PMID:9591243 NCBI chr 2:59,336,252...59,377,664
Ensembl chr 2:59,336,283...59,377,926
JBrowse link
G Ahsa1 activator of Hsp90 ATPase activity 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AHSA1 mRNA CTD PMID:24690739 NCBI chr 6:106,913,296...106,921,347
Ensembl chr 6:106,913,530...106,921,345
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B increases expression ISO Disulfiram results in increased expression of AKR1B1 mRNA CTD PMID:20566472 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Disulfiram results in increased expression of AKR1B10 mRNA CTD PMID:20566472 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852
JBrowse link
G Akr1c1 aldo-keto reductase family 1, member C1 increases expression ISO Disulfiram results in increased expression of AKR1C1 mRNA CTD PMID:20566472 NCBI chr17:65,810,474...65,837,385
Ensembl chr17:65,810,475...65,837,326
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Disulfiram results in increased expression of AKR1C3 mRNA CTD PMID:20566472 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G AKR1C3l1 aldo-keto reductase family 1 member C3-like 1 increases expression ISO Disulfiram results in increased expression of AKR1C1 mRNA CTD PMID:20566472 NCBI chr17:65,847,580...65,881,488
Ensembl chr17:65,835,634...65,881,488
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions EXP [Disulfiram co-treated with Lead] results in decreased activity of ALAD protein CTD PMID:2748540 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases activity
multiple interactions
EXP
ISO
Disulfiram results in decreased activity of ALDH1A1 protein
Disulfiram inhibits the reaction [ALDH1A1 protein results in decreased susceptibility to maphosphamide]
CTD PMID:8562935 PMID:10998257 PMID:21035945 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family, member A2 decreases activity ISO Disulfiram results in decreased activity of ALDH1A2 protein CTD PMID:22079344 NCBI chr 8:71,877,850...71,957,107
Ensembl chr 8:71,877,850...71,957,107
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity
decreases expression
multiple interactions
ISO
EXP
Disulfiram metabolite results in decreased activity of ALDH2 protein; Disulfiram results in decreased activity of ALDH2 protein
Disulfiram results in decreased expression of ALDH2 mRNA
[Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyceraldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to glycolaldehyde; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Glyoxal; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to hydroxypyruvic acid; [Disulfiram results in decreased activity of ALDH2 protein] which results in increased susceptibility to Pyruvaldehyde
CTD PMID:9585485 PMID:10513990 PMID:11142365 PMID:21334317 PMID:21376711 More... NCBI chr12:34,949,549...34,982,527 JBrowse link
G Aldh3a1 aldehyde dehydrogenase 3 family, member A1 increases metabolic processing ISO ALDH3A1 protein results in increased metabolism of Disulfiram CTD PMID:18591790 NCBI chr10:45,892,993...45,902,680
Ensembl chr10:45,892,924...45,902,681
JBrowse link
G Angptl4 angiopoietin-like 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ANGPTL4 mRNA CTD PMID:24690739 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
JBrowse link
G Ano6 anoctamin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ANO6 mRNA CTD PMID:24690739 NCBI chr 7:126,933,629...127,113,589
Ensembl chr 7:126,933,936...127,113,589
JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of APBB3 mRNA CTD PMID:24690739 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094
JBrowse link
G Apcdd1l APC down-regulated 1 like multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of APCDD1L mRNA CTD PMID:24690739 NCBI chr 3:162,587,484...162,658,362
Ensembl chr 3:162,582,252...162,658,073
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of APP mRNA CTD PMID:24690739 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Ar androgen receptor multiple interactions ISO [Disulfiram co-treated with cupric chloride] results in decreased expression of AR protein; Disulfiram inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein] CTD PMID:19789329 PMID:33049310 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ARC mRNA CTD PMID:24690739 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378
JBrowse link
G Asgr1 asialoglycoprotein receptor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ASGR1 mRNA CTD PMID:24690739 NCBI chr10:54,775,727...54,779,642
Ensembl chr10:54,776,024...54,779,631
JBrowse link
G Asmtl acetylserotonin O-methyltransferase-like multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ASMTL mRNA CTD PMID:24690739 NCBI chr12:16,315,335...16,321,607
Ensembl chr12:16,315,414...16,318,080
JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ASNS mRNA CTD PMID:24690739 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423
JBrowse link
G Atf1 activating transcription factor 1 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of ATF1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF1 protein] CTD PMID:15367699 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
JBrowse link
G Atf2 activating transcription factor 2 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of ATF2 protein; Copper promotes the reaction [Disulfiram results in decreased activity of ATF2 protein] CTD PMID:15367699 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
JBrowse link
G Atf3 activating transcription factor 3 multiple interactions
increases expression
ISO [Disulfiram binds to Copper] which results in decreased expression of ATF3 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA] CTD PMID:24690739 PMID:32661532 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631
JBrowse link
G Atg101 autophagy related 101 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATG101 mRNA CTD PMID:24690739 NCBI chr 7:132,398,477...132,407,643
Ensembl chr 7:132,398,483...132,407,633
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression EXP Disulfiram results in decreased expression of ATP2B1 mRNA CTD PMID:15003327 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Atp5mk ATP synthase membrane subunit k multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP5MK mRNA CTD PMID:24690739 NCBI chr 1:245,973,910...245,980,702
Ensembl chr 1:245,973,914...245,980,761
JBrowse link
G Atp6v0d1 ATPase H+ transporting V0 subunit D1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP6V0D1 mRNA CTD PMID:24690739 NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450
JBrowse link
G Atp6v1g1 ATPase H+ transporting V1 subunit G1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATP6V1G1 mRNA CTD PMID:24690739 NCBI chr 5:76,961,462...76,967,642
Ensembl chr 5:76,961,499...76,969,463
JBrowse link
G Atxn1l ataxin 1-like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ATXN1L mRNA CTD PMID:24690739
G Atxn3 ataxin 3 affects localization
increases response to substance
ISO Disulfiram affects the localization of ATXN3 protein alternative form
ATXN3 protein alternative form results in increased susceptibility to Disulfiram
CTD PMID:31378764 NCBI chr 6:121,072,228...121,107,902
Ensembl chr 6:121,074,448...121,107,902
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BAG3 mRNA CTD PMID:24690739 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions ISO [arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BAK1 protein CTD PMID:24126434 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO Disulfiram results in increased expression of BAX protein
[arsenic trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in increased expression of BAX protein; [Copper co-treated with Disulfiram] results in increased expression of BAX protein
CTD PMID:17079463 PMID:23033007 PMID:24126434 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bbs2 Bardet-Biedl syndrome 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of BBS2 mRNA CTD PMID:24690739 NCBI chr19:10,909,653...10,944,998
Ensembl chr19:10,909,619...10,944,993
JBrowse link
G Bccip BRCA2 and CDKN1A interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BCCIP mRNA CTD PMID:24690739 NCBI chr 1:188,512,544...188,524,957
Ensembl chr 1:188,512,367...188,524,958
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO [Arsenic Trioxide co-treated with Ascorbic Acid co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Copper co-treated with Disulfiram] results in decreased expression of BCL2 protein; [Disulfiram co-treated with cupric chloride] results in decreased expression of BCL2 protein CTD PMID:21911303 PMID:23033007 PMID:24126434 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of BDNF mRNA CTD PMID:24690739 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Bglap bone gamma-carboxyglutamate protein increases expression EXP Disulfiram results in increased expression of BGLAP mRNA CTD PMID:24496638 NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495
JBrowse link
G Bmp7 bone morphogenetic protein 7 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA] CTD PMID:22285649 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Brf2 BRF2, RNA polymerase III transcription initiation factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BRF2 mRNA CTD PMID:24690739 NCBI chr16:64,928,334...64,933,057
Ensembl chr16:64,928,300...64,933,059
JBrowse link
G Btk Bruton tyrosine kinase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of BTK mRNA CTD PMID:24690739 NCBI chr  X:97,722,796...97,762,315
Ensembl chr  X:97,722,802...97,761,853
JBrowse link
G C12H7orf61 chromosome 12 open reading frame, human C7orf61 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C7ORF61 mRNA CTD PMID:24690739 NCBI chr12:18,930,608...18,936,787 JBrowse link
G C1r complement C1r multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of C1R mRNA CTD PMID:24690739 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484
JBrowse link
G C1s complement C1s multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of C1S mRNA CTD PMID:24690739 NCBI chr 4:157,430,249...157,442,438
Ensembl chr 4:157,430,117...157,442,303
JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CACYBP mRNA CTD PMID:24690739 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177
JBrowse link
G Calcb calcitonin-related polypeptide, beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CALCB mRNA CTD PMID:24690739 NCBI chr 1:168,966,465...168,970,125
Ensembl chr 1:168,966,465...168,970,125
JBrowse link
G Cald1 caldesmon 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CALD1 mRNA CTD PMID:24690739 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CA2 mRNA CTD PMID:24690739 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Car7 carbonic anhydrase 7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CA7 mRNA CTD PMID:24690739 NCBI chr19:429,063...438,478
Ensembl chr19:429,075...438,467
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
EXP
ISO
[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of CASP3 protein]
[Disulfiram binds to Copper] which results in increased activity of CASP3 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of CASP3 protein]
Disulfiram results in increased activity of CASP3 protein
CTD PMID:11239917 PMID:17026967 PMID:17079463 PMID:24193513 PMID:24690739 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases activity ISO Disulfiram results in increased activity of CASP7 protein CTD PMID:17026967 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp9 caspase 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased activity of CASP9 protein CTD PMID:24690739 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase increases expression
multiple interactions
decreases expression
ISO Disulfiram results in increased expression of CAT mRNA
Zinc Sulfate inhibits the reaction [Disulfiram results in decreased expression of CAT mRNA]
CTD PMID:20566472 PMID:32712770 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CCAR1 protein CTD PMID:24690739 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526
JBrowse link
G Ccdc59 coiled-coil domain containing 59 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCDC59 mRNA CTD PMID:24690739 NCBI chr 7:41,142,760...41,149,143
Ensembl chr 7:41,142,760...41,149,143
JBrowse link
G Ccdc92 coiled-coil domain containing 92 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CCDC92 mRNA CTD PMID:24690739 NCBI chr12:31,796,102...31,823,333
Ensembl chr12:31,796,684...31,823,337
JBrowse link
G Cck cholecystokinin decreases expression
multiple interactions
EXP
ISO
Disulfiram results in decreased expression of CCK protein alternative form
[Disulfiram binds to Copper] which results in decreased expression of CCK mRNA
CTD PMID:8246921 PMID:24690739 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion
ISO [Disulfiram binds to Copper] which results in increased expression of CCL2 mRNA; [Zinc Sulfate co-treated with Disulfiram] inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]; Disulfiram inhibits the reaction [Lipopolysaccharides results in increased secretion of CCL2 protein]
Disulfiram results in decreased secretion of CCL2 protein
CTD PMID:24690739 PMID:32712770 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl26 C-C motif chemokine ligand 26 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCL26 mRNA CTD PMID:24690739 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein]
[Disulfiram binds to Copper] which results in increased expression of CCL5 mRNA
CTD PMID:19016906 PMID:24690739 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccna2 cyclin A2 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased expression of CCNA2 protein CTD PMID:15367699 NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
JBrowse link
G Ccnd2 cyclin D2 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA] CTD PMID:22285649 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495
JBrowse link
G Ccnk cyclin K multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CCNK mRNA CTD PMID:24690739 NCBI chr 6:127,090,115...127,113,195
Ensembl chr 6:127,090,569...127,113,191
JBrowse link
G Ccpg1 cell cycle progression 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CCPG1 mRNA CTD PMID:24690739 NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Disulfiram results in increased expression of CCR2 protein CTD PMID:32712770 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 multiple interactions ISO Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Nitric Oxide]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased abundance of Reactive Oxygen Species]; Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein] CTD PMID:19016906 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cd163 CD163 molecule multiple interactions
decreases expression
ISO [Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD163 mRNA
Disulfiram results in decreased expression of CD163 mRNA
CTD PMID:32712770 NCBI chr 4:157,085,080...157,118,470
Ensembl chr 4:157,085,093...157,117,878
JBrowse link
G Cd36 CD36 molecule multiple interactions
decreases expression
ISO [Zinc Sulfate co-treated with Disulfiram] results in decreased expression of CD36 mRNA
Disulfiram results in decreased expression of CD36 mRNA
CTD PMID:32712770 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd46 CD46 molecule multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD46 mRNA CTD PMID:24690739 NCBI chr13:106,575,586...106,606,325 JBrowse link
G Cd47 Cd47 molecule multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD47 mRNA CTD PMID:24690739 NCBI chr11:50,906,052...50,970,000
Ensembl chr11:50,906,177...50,969,425
JBrowse link
G Cd9 CD9 molecule multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CD9 mRNA CTD PMID:24690739 NCBI chr 4:158,256,328...158,289,136
Ensembl chr 4:158,256,328...158,289,222
JBrowse link
G Cdc42ep5 CDC42 effector protein 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDC42EP5 mRNA CTD PMID:24690739 NCBI chr 1:70,035,921...70,038,990 JBrowse link
G Cdh11 cadherin 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDH11 mRNA CTD PMID:24690739 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDH2 mRNA CTD PMID:24690739 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDK5R1 mRNA CTD PMID:24690739 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456
JBrowse link
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CDK5RAP3 mRNA CTD PMID:24690739 NCBI chr10:81,894,393...81,903,581
Ensembl chr10:81,894,393...81,903,590
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression
multiple interactions
ISO Disulfiram results in increased expression of CDKN1B protein
[Disulfiram binds to Copper] which results in increased expression of CDKN1B protein
CTD PMID:17079463 PMID:24690739 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDKN1C mRNA CTD PMID:24690739 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048
JBrowse link
G Cdkn2aip CDKN2A interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CDKN2AIP mRNA CTD PMID:24690739 NCBI chr16:44,536,147...44,546,216
Ensembl chr16:44,536,234...44,540,033
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CEMIP mRNA CTD PMID:24690739 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Cenpw centromere protein W multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CENPW mRNA CTD PMID:24690739 NCBI chr 1:27,525,324...27,530,464
Ensembl chr 1:27,525,324...27,530,464
JBrowse link
G Cfap53 cilia and flagella associated protein 53 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CFAP53 mRNA CTD PMID:24690739 NCBI chr18:67,884,651...67,955,873
Ensembl chr18:67,869,855...67,952,318
JBrowse link
G Cfb complement factor B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CFB mRNA CTD PMID:24690739 NCBI chr20:3,970,643...3,976,510 JBrowse link
G Chga chromogranin A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHGA mRNA CTD PMID:24690739 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Chmp1b charged multivesicular body protein 1B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHMP1B mRNA CTD PMID:24690739 NCBI chr18:60,740,349...60,742,879 JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CHORDC1 mRNA CTD PMID:24690739 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162
JBrowse link
G Cilp cartilage intermediate layer protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CILP mRNA CTD PMID:24690739 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251
JBrowse link
G Cirbp cold inducible RNA binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CIRBP mRNA CTD PMID:24690739 NCBI chr 7:9,533,857...9,538,899 JBrowse link
G Ckap4 cytoskeleton-associated protein 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CKAP4 mRNA CTD PMID:24690739 NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914
JBrowse link
G Cldn1 claudin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CLDN1 mRNA CTD PMID:24690739 NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
JBrowse link
G Clec7a C-type lectin domain containing 7A increases expression ISO Disulfiram results in increased expression of CLEC7A protein CTD PMID:32712770 NCBI chr 4:162,902,731...162,913,931
Ensembl chr 4:162,902,732...162,913,897
JBrowse link
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CLP1 mRNA CTD PMID:24690739 NCBI chr 3:69,806,774...69,818,633
Ensembl chr 3:69,806,778...69,810,421
JBrowse link
G Clta clathrin, light chain A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CLTA mRNA CTD PMID:24690739 NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472
JBrowse link
G Cmklr2 chemerin chemokine-like receptor 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CMKLR2 mRNA CTD PMID:24690739 NCBI chr 9:64,583,310...64,618,127
Ensembl chr 9:64,585,594...64,586,655
JBrowse link
G Cntnap1 contactin associated protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CNTNAP1 mRNA CTD PMID:24690739 NCBI chr10:86,109,850...86,125,612
Ensembl chr10:86,111,643...86,125,611
JBrowse link
G Col12a1 collagen type XII alpha 1 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL12A1 mRNA CTD PMID:24690739 NCBI chr 8:80,547,592...80,665,665
Ensembl chr 8:80,547,593...80,665,686
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL1A2 mRNA CTD PMID:24690739 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col3a1 collagen type III alpha 1 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL3A1 mRNA CTD PMID:24690739 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col4a1 collagen type IV alpha 1 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL4A1 mRNA CTD PMID:24690739 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Col5a1 collagen type V alpha 1 chain multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of COL5A1 mRNA CTD PMID:24690739 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
JBrowse link
G Commd9 COMM domain containing 9 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of COMMD9 mRNA CTD PMID:24690739 NCBI chr 3:88,175,909...88,190,427
Ensembl chr 3:88,175,987...88,190,439
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRABP2 mRNA CTD PMID:24690739 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [Disulfiram co-treated with Copper] results in decreased activity of CREB1 protein; Copper promotes the reaction [Disulfiram results in decreased activity of CREB1 protein] CTD PMID:15367699 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Creld2 cysteine-rich with EGF-like domains 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRELD2 mRNA CTD PMID:24690739 NCBI chr 7:119,909,626...119,916,556
Ensembl chr 7:119,909,633...119,916,543
JBrowse link
G Crim1 cysteine rich transmembrane BMP regulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CRIM1 mRNA CTD PMID:24690739 NCBI chr 6:16,695,864...16,870,264
Ensembl chr 6:16,697,829...16,870,259
JBrowse link
G Cript CXXC repeat containing interactor of PDZ3 domain multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRIPT mRNA CTD PMID:24690739 NCBI chr 6:7,581,428...7,589,384
Ensembl chr 6:7,580,703...7,589,399
JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRISPLD2 mRNA CTD PMID:24690739 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465
JBrowse link
G Cryab crystallin, alpha B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CRYAB mRNA CTD PMID:24690739 NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157
JBrowse link
G Cse1l chromosome segregation 1 like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CSE1L mRNA CTD PMID:24690739 NCBI chr 3:155,641,104...155,678,866
Ensembl chr 3:155,641,166...155,678,865
JBrowse link
G Csnk1e casein kinase 1, epsilon multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CSNK1E mRNA CTD PMID:24690739 NCBI chr 7:110,983,322...111,006,926
Ensembl chr 7:110,983,318...111,006,794
JBrowse link
G Csrnp1 cysteine and serine rich nuclear protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of AXUD1 mRNA CTD PMID:24690739 NCBI chr 8:119,704,712...119,717,767
Ensembl chr 8:119,704,713...119,718,183
JBrowse link
G Csrp2 cysteine and glycine-rich protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CSRP2 mRNA CTD PMID:24690739 NCBI chr 7:46,349,109...46,367,743
Ensembl chr 7:46,348,686...46,367,745
JBrowse link
G Cst6 cystatin E/M multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CST6 mRNA CTD PMID:24690739 NCBI chr 1:202,655,322...202,657,030
Ensembl chr 1:202,655,322...202,657,030
JBrowse link
G Cwc25 CWC25 spliceosome-associated protein homolog multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CWC25 mRNA CTD PMID:24690739 NCBI chr10:82,735,698...82,760,373
Ensembl chr10:82,736,995...82,760,354
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of CXCR4 mRNA CTD PMID:24690739 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA] CTD PMID:22285649 NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA] CTD PMID:22285649 NCBI chr 8:54,553,165...54,580,758
Ensembl chr 8:54,553,165...54,580,758
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions
increases expression
EXP GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA] CTD PMID:8390837 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Cyp2b2 cytochrome P450, family 2, subfamily b, polypeptide 2 increases expression
multiple interactions
EXP Disulfiram results in increased expression of CYP2B2 mRNA
GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA]
CTD PMID:8390837 NCBI chr 1:81,594,534...81,608,567
Ensembl chr 1:81,594,555...81,608,566
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity
decreases expression
EXP Disulfiram results in decreased activity of CYP2C11 protein
Disulfiram results in decreased expression of CYP2C11 protein
CTD PMID:9393675 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
decreases expression
ISO
EXP
[Disulfiram results in decreased activity of CYP2E1 protein] which affects the activity of Styrene; Disulfiram inhibits the reaction [[CYP2E1 protein results in increased metabolism of Chlorzoxazone] which results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased chemical synthesis of 6-hydroxychlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased metabolism of Chlorzoxazone]; Disulfiram inhibits the reaction [CYP2E1 protein results in increased oxidation of Halothane]
Disulfiram results in decreased expression of CYP2E1 mRNA; Disulfiram results in decreased expression of CYP2E1 protein
Disulfiram binds to and results in decreased activity of CYP2E1 protein
CTD PMID:1664256 PMID:8637342 PMID:9393675 PMID:10805064 PMID:18754103 More... NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp2r1 cytochrome P450, family 2, subfamily r, polypeptide 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CYP2R1 mRNA CTD PMID:24690739 NCBI chr 1:168,749,302...168,798,079
Ensembl chr 1:168,751,038...168,797,759
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression
increases response to substance
decreases activity
EXP
ISO
Disulfiram results in decreased expression of CYP3A2 mRNA
CYP3A4 protein results in increased susceptibility to Disulfiram
Disulfiram results in decreased activity of CYP3A2 protein
CTD PMID:9393675 PMID:21540358 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dag1 dystroglycan 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DAG1 mRNA CTD PMID:24690739 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325
JBrowse link
G Dbh dopamine beta-hydroxylase decreases activity
affects response to substance
ISO Disulfiram results in decreased activity of DBH protein
DBH gene SNP affects the susceptibility to Disulfiram
DBH gene polymorphism affects the susceptibility to Disulfiram
CTD PMID:90468 PMID:16163519 PMID:19462300 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248
JBrowse link
G Dcaf13 DDB1 and CUL4 associated factor 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DCAF13 mRNA CTD PMID:24690739 NCBI chr 7:70,160,983...70,196,142
Ensembl chr 7:70,160,941...70,196,142
JBrowse link
G Dcxr dicarbonyl and L-xylulose reductase multiple interactions ISO [Disulfiram co-treated with NADP] binds to DCXR protein CTD PMID:25526675 NCBI chr10:106,006,404...106,008,294 JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DDIT3 mRNA CTD PMID:24690739 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
JBrowse link
G Ddx39a DExD-box helicase 39A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DDX39A mRNA CTD PMID:24690739 NCBI chr19:24,418,743...24,427,422
Ensembl chr19:24,418,114...24,426,954
JBrowse link
G Dedd2 death effector domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DEDD2 mRNA CTD PMID:24690739 NCBI chr 1:80,789,084...80,807,789
Ensembl chr 1:80,792,000...80,807,714
JBrowse link
G Dhdh dihydrodiol dehydrogenase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DHDH mRNA CTD PMID:24690739 NCBI chr 1:95,954,361...95,965,262
Ensembl chr 1:95,953,092...95,965,197
JBrowse link
G Dhrs2 dehydrogenase/reductase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DHRS2 mRNA CTD PMID:24690739 NCBI chr15:28,688,881...28,703,646
Ensembl chr15:28,688,940...28,703,644
JBrowse link
G Dhrs3 dehydrogenase/reductase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DHRS3 mRNA CTD PMID:24690739 NCBI chr 5:156,747,939...156,782,420
Ensembl chr 5:156,747,962...156,782,417
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DKK3 mRNA CTD PMID:24690739 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590
JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DLL1 mRNA CTD PMID:24690739 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179
JBrowse link
G Dnaja1 DnaJ heat shock protein family (Hsp40) member A1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJA1 mRNA CTD PMID:24690739 NCBI chr 5:55,842,414...55,853,326
Ensembl chr 5:55,842,426...55,853,967
JBrowse link
G Dnaja4 DnaJ heat shock protein family (Hsp40) member A4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJA4 mRNA CTD PMID:24690739 NCBI chr 8:55,085,246...55,102,715
Ensembl chr 8:55,085,464...55,101,207
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJB1 mRNA CTD PMID:24690739 NCBI chr19:24,522,717...24,526,458
Ensembl chr19:24,522,717...24,526,458
JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJB6 mRNA CTD PMID:24690739 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659
JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DNAJC3 mRNA CTD PMID:24690739 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181
JBrowse link
G Dph3 diphthamide biosynthesis 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DPH3 mRNA CTD PMID:24690739 NCBI chr16:7,288,295...7,293,734
Ensembl chr16:7,282,705...7,291,265
JBrowse link
G Dram1 DNA-damage regulated autophagy modulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DRAM1 mRNA CTD PMID:24690739 NCBI chr 7:22,742,794...22,776,888
Ensembl chr 7:22,742,849...22,776,765
JBrowse link
G Dse dermatan sulfate epimerase multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of DSE mRNA CTD PMID:24690739 NCBI chr20:26,118,194...26,196,889
Ensembl chr20:26,118,196...26,196,992
JBrowse link
G Dusp2 dual specificity phosphatase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DUSP2 mRNA CTD PMID:24690739 NCBI chr 3:114,556,325...114,558,510
Ensembl chr 3:114,556,325...114,558,499
JBrowse link
G Dusp5 dual specificity phosphatase 5 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DUSP5 mRNA CTD PMID:24690739 NCBI chr 1:252,538,408...252,555,320
Ensembl chr 1:252,538,449...252,551,818
JBrowse link
G Dynll2 dynein light chain LC8-type 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of DYNLL2 mRNA CTD PMID:24690739 NCBI chr10:72,767,035...72,785,824
Ensembl chr10:72,767,035...72,785,805
JBrowse link
G Eaf1 ELL associated factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EAF1 mRNA CTD PMID:24690739 NCBI chr16:6,698,322...6,713,071
Ensembl chr16:6,698,322...6,713,071
JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of EDIL3 mRNA CTD PMID:24690739 NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008
JBrowse link
G Eed embryonic ectoderm development multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EED mRNA CTD PMID:24690739 NCBI chr 1:143,867,875...143,895,008
Ensembl chr 1:143,867,875...143,894,974
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of EFEMP1 mRNA CTD PMID:24690739 NCBI chr14:102,610,813...102,690,027
Ensembl chr14:102,610,908...102,690,018
JBrowse link
G Egr1 early growth response 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EGR1 mRNA CTD PMID:24690739 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of EIF4A3 mRNA CTD PMID:24690739 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057
JBrowse link
G Ell2 elongation factor for RNA polymerase II 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ELL2 mRNA CTD PMID:24690739 NCBI chr 2:5,189,375...5,258,781
Ensembl chr 2:5,189,971...5,258,781
JBrowse link
G Elof1 elongation factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ELOF1 mRNA CTD PMID:24690739 NCBI chr 8:20,645,336...20,650,888
Ensembl chr 8:20,645,336...20,650,579
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Disulfiram binds to and results in decreased activity of ESR1 protein CTD PMID:33049310 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ETS1 mRNA CTD PMID:24690739 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G F12 coagulation factor XII multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of F12 mRNA CTD PMID:24690739 NCBI chr17:9,207,683...9,215,530
Ensembl chr17:9,207,683...9,215,530
JBrowse link
G Fam210a family with sequence similarity 210, member A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FAM210A mRNA CTD PMID:24690739 NCBI chr18:61,846,447...61,886,123
Ensembl chr18:61,852,907...61,886,171
JBrowse link
G Fam234a family with sequence similarity 234, member A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of FAM234A mRNA CTD PMID:24690739 NCBI chr10:15,232,267...15,263,529
Ensembl chr10:15,232,278...15,263,488
JBrowse link
G Fam32a family with sequence similarity 32, member A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FAM32A mRNA CTD PMID:24690739 NCBI chr16:17,603,054...17,607,376
Ensembl chr16:17,603,946...17,607,398
JBrowse link
G Fech ferrochelatase increases expression ISO Disulfiram results in increased expression of FECH mRNA CTD PMID:20566472 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FKBP1A mRNA CTD PMID:24690739 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Flcn folliculin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FLCN mRNA CTD PMID:24690739 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Fndc11 fibronectin type III domain containing 11 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FNDC11 mRNA CTD PMID:24690739 NCBI chr 3:168,330,607...168,333,111
Ensembl chr 3:168,330,602...168,334,617
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOS mRNA CTD PMID:24690739 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOSB mRNA CTD PMID:24690739 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465
JBrowse link
G Foxa3 forkhead box A3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOXA3 mRNA CTD PMID:24690739 NCBI chr 1:78,662,067...78,672,321
Ensembl chr 1:78,662,431...78,672,155
JBrowse link
G Foxj1 forkhead box J1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FOXJ1 mRNA CTD PMID:24690739 NCBI chr10:101,566,299...101,570,249 JBrowse link
G Frg1 FSHD region gene 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FRG1 mRNA CTD PMID:24690739 NCBI chr16:50,925,783...50,946,661
Ensembl chr16:50,925,803...50,946,661
JBrowse link
G Fshb follicle stimulating hormone subunit beta multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370
JBrowse link
G Fshr follicle stimulating hormone receptor multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA] CTD PMID:22285649 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Fstl1 follistatin-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of FSTL1 mRNA CTD PMID:24690739 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677
JBrowse link
G Ftcd formimidoyltransferase cyclodeaminase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of FTCD mRNA CTD PMID:24690739 NCBI chr20:12,055,203...12,068,717
Ensembl chr20:12,055,208...12,068,735
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Disulfiram results in increased expression of FTL mRNA CTD PMID:20566472 NCBI chr 1:95,936,390...95,938,234
Ensembl chr 1:95,936,387...95,939,725
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Disulfiram results in increased expression of G6PD mRNA CTD PMID:20566472 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gadd45b growth arrest and DNA-damage-inducible, beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GADD45B mRNA CTD PMID:24690739 NCBI chr 7:8,778,004...8,780,306
Ensembl chr 7:8,778,007...8,780,046
JBrowse link
G Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GALNT10 mRNA CTD PMID:24690739 NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GAS6 mRNA CTD PMID:24690739 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gata2 GATA binding protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GATA2 mRNA CTD PMID:24690739 NCBI chr 4:120,654,205...120,667,763
Ensembl chr 4:120,658,986...120,667,761
JBrowse link
G Gbp4 guanylate binding protein 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GBP4 mRNA CTD PMID:24690739 NCBI chr 2:231,304,910...231,318,883
Ensembl chr 2:231,305,244...231,318,879
JBrowse link
G Gcc1 GRIP and coiled-coil domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GCC1 mRNA CTD PMID:24690739 NCBI chr 4:57,030,817...57,042,682
Ensembl chr 4:57,032,314...57,042,663
JBrowse link
G Gcgr glucagon receptor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GCGR mRNA CTD PMID:24690739 NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Disulfiram results in increased expression of GCLC mRNA CTD PMID:20566472 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Disulfiram results in increased expression of GCLM mRNA CTD PMID:20566472 NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GEM mRNA CTD PMID:24690739 NCBI chr 5:25,214,309...25,225,222
Ensembl chr 5:25,214,309...25,225,222
JBrowse link
G Gemin6 gem (nuclear organelle) associated protein 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GEMIN6 mRNA CTD PMID:24690739 NCBI chr 6:14,786,086...14,790,631
Ensembl chr 6:14,786,070...14,790,612
JBrowse link
G Gh1 growth hormone 1 multiple interactions EXP GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA]; GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA] CTD PMID:8390837 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078
JBrowse link
G Glg1 golgi glycoprotein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GLG1 mRNA CTD PMID:24690739 NCBI chr19:39,124,892...39,224,178
Ensembl chr19:39,124,641...39,224,178
JBrowse link
G Glrx2 glutaredoxin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GLRX2 mRNA CTD PMID:24690739 NCBI chr13:55,481,875...55,504,737
Ensembl chr13:55,482,694...55,492,831
JBrowse link
G Gosr2 golgi SNAP receptor complex member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GOSR2 mRNA CTD PMID:24690739 NCBI chr10:88,585,291...88,605,642
Ensembl chr10:88,586,299...88,605,625
JBrowse link
G Gpsm1 G-protein signaling modulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GPSM1 mRNA CTD PMID:24690739 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827
JBrowse link
G Gpt2 glutamic--pyruvic transaminase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GPT2 mRNA CTD PMID:24690739 NCBI chr19:21,526,800...21,561,314
Ensembl chr19:21,517,621...21,560,610
JBrowse link
G Gpx3 glutathione peroxidase 3 increases expression ISO Disulfiram results in increased expression of GPX3 mRNA CTD PMID:20566472 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gramd1a GRAM domain containing 1A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GRAMD1A mRNA CTD PMID:24690739 NCBI chr 1:86,367,001...86,393,348
Ensembl chr 1:86,367,001...86,393,336
JBrowse link
G Gramd2b GRAM domain containing 2B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GRAMD2B mRNA CTD PMID:24690739 NCBI chr18:49,884,014...49,981,955
Ensembl chr18:49,884,014...49,981,953
JBrowse link
G Grwd1 glutamate-rich WD repeat containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GRWD1 mRNA CTD PMID:24690739 NCBI chr 1:96,301,260...96,306,962
Ensembl chr 1:96,301,261...96,307,201
JBrowse link
G Gsdme gasdermin E multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of GSDME mRNA CTD PMID:24690739 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806
JBrowse link
G Gsr glutathione-disulfide reductase increases expression ISO Disulfiram results in increased expression of GSR mRNA CTD PMID:20566472 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gtf2b general transcription factor IIB multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of GTF2B mRNA CTD PMID:24690739 NCBI chr 2:231,767,317...231,785,626
Ensembl chr 2:231,767,238...231,785,651
JBrowse link
G H2ac20 H2A clustered histone 20 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2AC20 mRNA CTD PMID:24690739 NCBI chr 2:183,779,879...183,780,324 JBrowse link
G H2ax H2A.X variant histone multiple interactions ISO Disulfiram inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein] CTD PMID:28300663 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G H2bc12 H2B clustered histone 12 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2BC12 mRNA CTD PMID:24690739 NCBI chr17:42,485,746...42,486,126 JBrowse link
G H3f4 H3.4 histone multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H3-4 mRNA CTD PMID:24690739 NCBI chr10:43,740,797...43,741,207 JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of H6PD mRNA CTD PMID:24690739 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171
JBrowse link
G Hba-a2 hemoglobin alpha, adult chain 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HBA1 mRNA CTD PMID:24690739 NCBI chr10:15,323,830...15,324,677 JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HBEGF mRNA CTD PMID:24690739 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hes1 hes family bHLH transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HES1 mRNA CTD PMID:24690739 NCBI chr11:70,705,763...70,708,176
Ensembl chr11:70,705,764...70,708,192
JBrowse link
G Hes6 hes family bHLH transcription factor 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HES6 mRNA CTD PMID:24690739 NCBI chr 9:92,001,838...92,003,580
Ensembl chr 9:92,001,841...92,003,559
JBrowse link
G Hist1h2bl histone cluster 1 H2B family member l multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H2BC8 mRNA CTD PMID:24690739 NCBI chr17:42,708,646...42,709,435 JBrowse link
G Hist1h3b histone cluster 1, H3b multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of H3C12 mRNA CTD PMID:24690739 NCBI chr17:42,722,805...42,723,925 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
ISO Disulfiram results in increased expression of HMOX1 mRNA
[Disulfiram binds to Copper] which results in decreased expression of HMOX1 mRNA; [Disulfiram co-treated with Zinc Sulfate] results in increased expression of HMOX1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]
CTD PMID:20566472 PMID:24690739 PMID:32661532 PMID:32712770 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HNRNPA2B1 mRNA CTD PMID:24690739 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hoxa1 homeobox A1 multiple interactions ISO Disulfiram inhibits the reaction [Vitamin A results in increased expression of HOXA1 mRNA] CTD PMID:23696197 NCBI chr 4:81,255,814...81,258,504
Ensembl chr 4:81,255,883...81,258,504
JBrowse link
G Hoxd1 homeo box D1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HOXD1 mRNA CTD PMID:24690739 NCBI chr 3:59,665,629...59,667,769
Ensembl chr 3:59,665,629...59,667,769
JBrowse link
G Hrk harakiri, BCL2 interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HRK mRNA CTD PMID:24690739 NCBI chr12:38,387,484...38,409,652 JBrowse link
G Hs3st2 heparan sulfate-glucosamine 3-sulfotransferase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HS3ST2 mRNA CTD PMID:24690739 NCBI chr 1:175,956,161...176,077,400
Ensembl chr 1:175,956,157...176,077,399
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 multiple interactions ISO [Disulfiram co-treated with NAD] binds to HSD11B1 protein CTD PMID:25526675 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO Disulfiram results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSP90AA1 mRNA CTD PMID:24690739 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSP90AB1 mRNA CTD PMID:24690739 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA1A mRNA CTD PMID:24690739
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression
multiple interactions
ISO Disulfiram results in increased expression of HSPA1B mRNA
[Disulfiram binds to Copper] which results in decreased expression of HSPA1B mRNA
CTD PMID:20566472 PMID:24690739 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA1L mRNA CTD PMID:24690739 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA4 mRNA CTD PMID:24690739 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA8 mRNA CTD PMID:24690739 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPB1 mRNA CTD PMID:24690739 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspb8 heat shock protein family B (small) member 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPB8 mRNA CTD PMID:24690739 NCBI chr12:40,176,405...40,205,002
Ensembl chr12:40,176,532...40,191,185
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPH1 mRNA CTD PMID:24690739 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HTR2B mRNA CTD PMID:24690739 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Id2 inhibitor of DNA binding 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ID2 mRNA CTD PMID:24690739 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400
JBrowse link
G Ier5 immediate early response 5 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of IER5 mRNA CTD PMID:24690739 NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFIT2 mRNA CTD PMID:24690739 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635
JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFIT3 mRNA CTD PMID:24690739 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307
JBrowse link
G Ifngr2 interferon gamma receptor 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IFNGR2 mRNA CTD PMID:24690739 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005
JBrowse link
G Igf2r insulin-like growth factor 2 receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IGF2R mRNA CTD PMID:24690739 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501
JBrowse link
G Igfbp7 insulin-like growth factor binding protein 7 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IGFBP7 mRNA; [Disulfiram binds to Copper] which results in increased expression of IGFBP7 protein CTD PMID:24690739 NCBI chr14:30,737,414...30,797,317
Ensembl chr14:30,737,164...30,797,314
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL1A mRNA CTD PMID:24690739 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL1B mRNA; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:24690739 PMID:32712770 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of IL6 mRNA; [Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:24690739 PMID:32712770 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Insig1 insulin induced gene 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of INSIG1 mRNA CTD PMID:24690739 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Irf8 interferon regulatory factor 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of IRF8 mRNA CTD PMID:24690739 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Isy1 ISY1 splicing factor homolog multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ISY1 mRNA CTD PMID:24690739 NCBI chr 4:120,276,535...120,297,227
Ensembl chr 4:120,276,292...120,297,188
JBrowse link
G Itga11 integrin subunit alpha 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGA11 mRNA CTD PMID:24690739 NCBI chr 8:63,145,950...63,254,717
Ensembl chr 8:63,146,001...63,254,407
JBrowse link
G Itga3 integrin subunit alpha 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGA3 mRNA CTD PMID:24690739 NCBI chr10:79,990,160...80,022,206
Ensembl chr10:79,990,161...80,022,118
JBrowse link
G Itgam integrin subunit alpha M increases expression ISO Disulfiram results in increased expression of ITGAM protein CTD PMID:32712770 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503
JBrowse link
G Itgav integrin subunit alpha V multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGAV mRNA CTD PMID:24690739 NCBI chr 3:68,838,524...68,926,653
Ensembl chr 3:68,838,189...68,926,639
JBrowse link
G Itgb1 integrin subunit beta 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGB1 mRNA CTD PMID:24690739 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb5 integrin subunit beta 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ITGB5 mRNA CTD PMID:24690739 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Jag2 jagged canonical Notch ligand 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of JAG2 mRNA CTD PMID:24690739 NCBI chr 6:131,983,056...132,005,359
Ensembl chr 6:131,983,056...132,005,818
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO [Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased expression of and results in increased phosphorylation of JUN protein; [Copper co-treated with Disulfiram] results in increased expression of and results in increased phosphorylation of JUN protein; [Disulfiram co-treated with cupric chloride co-treated with Doxorubicin] results in increased expression of and results in increased phosphorylation of JUN protein; Acetylcysteine inhibits the reaction [[Copper co-treated with Disulfiram] results in increased phosphorylation of JUN protein]; pyrazolanthrone inhibits the reaction [[Disulfiram co-treated with Copper co-treated with Doxorubicin] results in increased phosphorylation of and results in increased expression of JUN protein] CTD PMID:21911303 PMID:23033007 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kcng1 potassium voltage-gated channel modifier subfamily G member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KCNG1 mRNA CTD PMID:24690739 NCBI chr 3:156,960,717...156,992,877
Ensembl chr 3:156,973,156...156,992,635
JBrowse link
G Khdrbs3 KH RNA binding domain containing, signal transduction associated 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KHDRBS3 mRNA CTD PMID:24690739 NCBI chr 7:100,837,707...100,995,644
Ensembl chr 7:100,837,934...100,988,460
JBrowse link
G Klf10 Kruppel-like factor 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KLF10 mRNA CTD PMID:24690739 NCBI chr 7:69,467,658...69,473,726
Ensembl chr 7:69,465,619...69,473,994
JBrowse link
G Klhl22 kelch-like family member 22 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KLHL22 mRNA CTD PMID:24690739 NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770
JBrowse link
G Klhl5 kelch-like family member 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of KLHL5 mRNA CTD PMID:24690739 NCBI chr14:43,144,254...43,206,192
Ensembl chr14:43,144,257...43,184,238
JBrowse link
G Krt75 keratin 75 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of KRT75 mRNA CTD PMID:24690739 NCBI chr 7:132,687,101...132,697,360
Ensembl chr 7:132,688,237...132,697,345
JBrowse link
G Lamc1 laminin subunit gamma 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LAMC1 mRNA CTD PMID:24690739 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492
JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LAMTOR3 mRNA CTD PMID:24690739 NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607
JBrowse link
G Lemd2 LEM domain nuclear envelope protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LEMD2 mRNA CTD PMID:24690739 NCBI chr20:5,282,397...5,296,621
Ensembl chr20:5,282,397...5,296,626
JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of BMP7 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CCND2 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP17A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of CYP19A1 mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of FSHR mRNA]; Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor multiple interactions ISO Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]; Tretinoin inhibits the reaction [Disulfiram inhibits the reaction [[FSHB protein co-treated with LHB protein co-treated with Testosterone] results in increased expression of LHCGR mRNA]] CTD PMID:22285649 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Limch1 LIM and calponin homology domains 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LIMCH1 mRNA CTD PMID:24690739 NCBI chr14:41,112,579...41,425,185
Ensembl chr14:41,114,803...41,425,191
JBrowse link
G Lipt1 lipoyltransferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LIPT1 mRNA CTD PMID:24690739 NCBI chr 9:40,107,938...40,118,268
Ensembl chr 9:40,098,615...40,113,565
JBrowse link
G Lmcd1 LIM and cysteine-rich domains 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LMCD1 mRNA CTD PMID:24690739 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046
JBrowse link
G Lmtk2 lemur tyrosine kinase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LMTK2 mRNA CTD PMID:24690739 NCBI chr12:10,426,772...10,508,750
Ensembl chr12:10,426,777...10,508,750
JBrowse link
G LOC100125368 zinc finger protein LOC100125368 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF77 mRNA CTD PMID:24690739 NCBI chr 7:8,037,649...8,060,640
Ensembl chr 7:8,037,652...8,060,035
JBrowse link
G LOC102555377 zinc finger protein 182-like multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of ZNF34 mRNA CTD PMID:24690739 NCBI chr 1:62,457,455...62,493,728
Ensembl chr 1:62,457,716...62,493,726
JBrowse link
G LOC685680 similar to TPA-induced transmembrane protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C3ORF52 mRNA CTD PMID:24690739 NCBI chr11:55,166,986...55,192,273
Ensembl chr11:55,166,678...55,192,292
JBrowse link
G LOC686035 similar to heat shock 70kDa protein 6 (HSP70B) multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of HSPA6 mRNA CTD PMID:24690739 NCBI chr13:83,271,340...83,275,267 JBrowse link
G Loricrin loricrin cornified envelope precursor protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LORICRIN mRNA CTD PMID:24690739 NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807
JBrowse link
G Lratd2 LRAT domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LRATD2 mRNA CTD PMID:24690739 NCBI chr 7:92,376,713...92,387,045
Ensembl chr 7:92,362,194...92,388,189
JBrowse link
G Lrp8 LDL receptor related protein 8 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LRP8 mRNA CTD PMID:24690739 NCBI chr 5:122,563,468...122,635,434
Ensembl chr 5:122,563,453...122,631,352
JBrowse link
G Lsmem1 leucine-rich single-pass membrane protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of LSMEM1 mRNA CTD PMID:24690739 NCBI chr 6:57,250,221...57,262,240
Ensembl chr 6:57,252,056...57,261,653
JBrowse link
G Ltb4r leukotriene B4 receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of LTB4R mRNA CTD PMID:24690739 NCBI chr15:29,263,126...29,265,716 JBrowse link
G Luc7l3 LUC7-like 3 pre-mRNA splicing factor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of CROP mRNA CTD PMID:24690739 NCBI chr10:79,240,050...79,276,555
Ensembl chr10:79,240,563...79,276,538
JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MACF1 mRNA CTD PMID:24690739 NCBI chr 5:135,623,729...135,949,097
Ensembl chr 5:135,623,742...135,945,905
JBrowse link
G Mad2l1bp MAD2L1 binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAD2L1BP mRNA CTD PMID:24690739 NCBI chr 9:14,832,133...14,836,458
Ensembl chr 9:14,832,132...14,837,447
JBrowse link
G Mafb MAF bZIP transcription factor B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAFB mRNA CTD PMID:24690739 NCBI chr 3:148,998,111...149,000,031
Ensembl chr 3:148,998,122...149,000,031
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Disulfiram results in increased expression of MAFF mRNA CTD PMID:20566472 NCBI chr 7:110,912,499...110,923,851
Ensembl chr 7:110,912,499...110,923,851
JBrowse link
G Mafg MAF bZIP transcription factor G increases expression ISO Disulfiram results in increased expression of MAFG mRNA CTD PMID:20566472 NCBI chr10:105,903,307...105,911,845
Ensembl chr10:105,903,237...105,912,026
JBrowse link
G Mafk MAF bZIP transcription factor K increases expression ISO Disulfiram results in increased expression of MAFK mRNA CTD PMID:20566472 NCBI chr12:14,834,628...14,856,414
Ensembl chr12:14,833,984...14,837,048
Ensembl chr12:14,833,984...14,837,048
JBrowse link
G Magoh mago homolog, exon junction complex subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAGOH mRNA CTD PMID:24690739 NCBI chr 5:122,639,268...122,646,650
Ensembl chr 5:122,639,308...122,646,617
JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MAN1B1 mRNA CTD PMID:24690739 NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006
JBrowse link
G Maoa monoamine oxidase A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAOA mRNA CTD PMID:24690739 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP1LC3B mRNA CTD PMID:24690739 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Map2k3 mitogen activated protein kinase kinase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP2K3 mRNA CTD PMID:24690739 NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAP3K13 mRNA CTD PMID:24690739 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181
JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MAP3K20 mRNA CTD PMID:24690739 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased phosphorylation of MAPK1 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK1 protein CTD PMID:23033007 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Copper co-treated with Disulfiram co-treated with gemcitabine] results in increased phosphorylation of MAPK3 protein; [Copper co-treated with Disulfiram] results in increased phosphorylation of MAPK3 protein CTD PMID:23033007 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions EXP
ISO
[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein; bathocuproine sulfonate inhibits the reaction [[Disulfiram binds to cupric chloride] which results in increased activity of MAPK8 protein]
[Disulfiram binds to Copper] which results in increased phosphorylation of MAPK8 protein
CTD PMID:11239917 PMID:24690739 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased phosphorylation of MAPK9 protein CTD PMID:24690739 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MAPRE2 mRNA CTD PMID:24690739 NCBI chr18:15,028,675...15,169,553 JBrowse link
G Mcm2 minichromosome maintenance complex component 2 multiple interactions
decreases expression
ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM2 mRNA] CTD PMID:19789329 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Mcm5 minichromosome maintenance complex component 5 multiple interactions
decreases expression
ISO cupric chloride promotes the reaction [Disulfiram results in decreased expression of MCM5 mRNA] CTD PMID:19789329 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Disulfiram results in increased expression of ME1 mRNA CTD PMID:20566472 NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304
JBrowse link
G Mfsd3 major facilitator superfamily domain containing 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MFSD3 mRNA CTD PMID:24690739 NCBI chr 7:108,419,644...108,423,469
Ensembl chr 7:108,421,350...108,423,461
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase multiple interactions
decreases activity
increases degradation
ISO
EXP
[Disulfiram binds to Copper] which results in decreased expression of and results in decreased activity of MGMT protein; [Disulfiram co-treated with cupric chloride] affects the expression of and affects the activity of MGMT protein; bortezomib inhibits the reaction [Disulfiram results in increased degradation of MGMT protein]; Disulfiram inhibits the reaction [O(6)-benzylguanine binds to MGMT protein]; Disulfiram results in decreased expression of and results in decreased activity of MGMT protein
Disulfiram results in decreased activity of MGMT protein
CTD PMID:24193513 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Disulfiram results in increased expression of MGST1 mRNA CTD PMID:20566472 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Midn midnolin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MIDN mRNA CTD PMID:24690739 NCBI chr 7:9,548,100...9,559,605
Ensembl chr 7:9,549,650...9,559,752
JBrowse link
G Mix23 mitochondrial matrix import factor 23 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MIX23 mRNA CTD PMID:24690739 NCBI chr11:64,660,711...64,681,000
Ensembl chr11:64,660,711...64,681,000
JBrowse link
G Mmp10 matrix metallopeptidase 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MMP10 mRNA CTD PMID:24690739 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO Disulfiram results in decreased expression of MMP2 CTD PMID:18047805 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MMP3 mRNA CTD PMID:24690739 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO Disulfiram results in decreased expression of MMP9 CTD PMID:18047805 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mppe1 metallophosphoesterase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MPPE1 mRNA CTD PMID:24690739 NCBI chr18:60,763,418...60,781,553
Ensembl chr18:60,763,419...60,781,553
JBrowse link
G Mrpl10 mitochondrial ribosomal protein L10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL10 mRNA CTD PMID:24690739 NCBI chr10:82,026,031...82,034,451
Ensembl chr10:82,026,031...82,034,443
JBrowse link
G Mrpl18 mitochondrial ribosomal protein L18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL18 mRNA CTD PMID:24690739 NCBI chr 1:47,837,169...47,841,987
Ensembl chr 1:47,836,561...47,841,987
JBrowse link
G Mrpl45 mitochondrial ribosomal protein L45 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MRPL45 mRNA CTD PMID:24690739 NCBI chr10:82,308,650...82,320,474
Ensembl chr10:82,308,427...82,320,474
JBrowse link
G Mt-co1 mitochondrially encoded cytochrome c oxidase I affects activity
affects expression
EXP Disulfiram affects the activity of COX1 protein
Disulfiram affects the expression of COX1 mRNA
CTD PMID:17936468 NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MT1A mRNA CTD PMID:24690739 NCBI chr19:10,826,032...10,827,048 JBrowse link
G Mt2A metallothionein 2A increases expression
multiple interactions
ISO Disulfiram results in increased expression of MT2A mRNA
cupric chloride promotes the reaction [Disulfiram results in increased expression of MT2A mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA]
CTD PMID:19789329 PMID:32661532 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Mt3 metallothionein 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MT3 mRNA CTD PMID:24690739 NCBI chr19:10,848,754...10,850,158
Ensembl chr19:10,848,755...10,850,158
JBrowse link
G Mtf1 metal-regulatory transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MTF1 mRNA; MTF1 protein affects the reaction [Disulfiram results in increased expression of ATF3 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of HMOX1 mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT1M mRNA]; MTF1 protein affects the reaction [Disulfiram results in increased expression of MT2A mRNA] CTD PMID:24690739 PMID:32661532 NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136
JBrowse link
G Mx1 MX dynamin like GTPase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MX1 mRNA CTD PMID:24690739 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507
JBrowse link
G Mylip myosin regulatory light chain interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of MYLIP mRNA CTD PMID:24690739 NCBI chr17:19,286,649...19,308,295
Ensembl chr17:19,286,650...19,308,295
JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of MYLK mRNA CTD PMID:24690739 NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
JBrowse link
G Nat14 N-acetyltransferase 14 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NAT14 mRNA CTD PMID:24690739 NCBI chr 1:68,910,599...68,913,452
Ensembl chr 1:68,910,601...68,912,733
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCEH1 mRNA CTD PMID:24690739 NCBI chr 2:110,074,985...110,135,592
Ensembl chr 2:110,074,957...110,135,588
JBrowse link
G Ncoa7 nuclear receptor coactivator 7 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCOA7 mRNA CTD PMID:24690739 NCBI chr 1:26,856,228...27,016,950
Ensembl chr 1:26,856,530...27,015,871
JBrowse link
G Ncstn nicastrin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NCSTN mRNA CTD PMID:24690739 NCBI chr13:84,530,442...84,546,454
Ensembl chr13:84,530,440...84,546,454
JBrowse link
G Nefh neurofilament heavy chain multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NEFH mRNA CTD PMID:24690739 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351
JBrowse link
G Nfe2l3 NFE2 like bZIP transcription factor 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NFE2L3 mRNA CTD PMID:24690739 NCBI chr 4:80,506,756...80,534,629
Ensembl chr 4:80,506,756...80,534,629
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NFKB1 mRNA CTD PMID:24690739 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases degradation
multiple interactions
EXP
ISO
Disulfiram results in decreased degradation of NFKBIA protein
[Disulfiram binds to Copper] which results in increased expression of NFKBIA protein
CTD PMID:10418820 PMID:24690739 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nfkbib NFKB inhibitor beta multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NFKBIB protein CTD PMID:24690739 NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862
JBrowse link
G Ngdn neuroguidin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NGDN mRNA CTD PMID:24690739 NCBI chr15:28,489,950...28,497,286
Ensembl chr15:28,490,040...28,519,654
JBrowse link
G Niban1 niban apoptosis regulator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NIBAN1 mRNA CTD PMID:24690739 NCBI chr13:63,674,240...63,827,748
Ensembl chr13:63,674,171...63,827,729
JBrowse link
G Nol12 nucleolar protein 12 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NOL12 mRNA CTD PMID:24690739 NCBI chr 7:110,493,294...110,498,908
Ensembl chr 7:110,493,246...110,498,907
JBrowse link
G Nos2 nitric oxide synthase 2 affects expression EXP Disulfiram affects the expression of NOS2 mRNA CTD PMID:17936468 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nosip nitric oxide synthase interacting protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NOSIP mRNA CTD PMID:24690739 NCBI chr 1:95,543,329...95,559,101
Ensembl chr 1:95,543,360...95,558,650
JBrowse link
G Npepl1 aminopeptidase-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NPEPL1 mRNA CTD PMID:24690739 NCBI chr 3:162,893,891...162,906,492
Ensembl chr 3:162,893,943...162,906,492
JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NPPB mRNA CTD PMID:24690739 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168
JBrowse link
G Nptx2 neuronal pentraxin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NPTX2 mRNA CTD PMID:24690739 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression
increases activity
ISO
EXP
Disulfiram results in increased expression of NQO1 mRNA
Disulfiram results in increased activity of NQO1 protein
CTD PMID:16045903 PMID:20566472 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Disulfiram binds to and affects the activity of NR1I2 protein
Disulfiram binds to and results in increased activity of NR1I2 protein
CTD PMID:33049310 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nrarp Notch-regulated ankyrin repeat protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NRARP mRNA CTD PMID:24690739 NCBI chr 3:7,992,582...7,995,136
Ensembl chr 3:7,992,552...7,995,133
JBrowse link
G Nras NRAS proto-oncogene, GTPase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NRAS mRNA CTD PMID:24690739 NCBI chr 2:190,582,885...190,593,509
Ensembl chr 2:190,582,918...190,591,626
JBrowse link
G Nrp1 neuropilin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NRP1 mRNA CTD PMID:24690739 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633
JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of NT5E mRNA CTD PMID:24690739 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881
JBrowse link
G Nubp1 nucleotide binding protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NUBP1 mRNA CTD PMID:24690739 NCBI chr10:5,260,237...5,270,835 JBrowse link
G Nxf1 nuclear RNA export factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NXF1 mRNA CTD PMID:24690739 NCBI chr 1:205,655,442...205,668,637
Ensembl chr 1:205,655,375...205,668,636
JBrowse link
G Nxt2 nuclear transport factor 2-like export factor 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of NXT2 mRNA CTD PMID:24690739 NCBI chr  X:105,855,616...105,862,902
Ensembl chr  X:105,855,608...105,862,899
JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of OASL mRNA CTD PMID:24690739 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641
JBrowse link
G Osmr oncostatin M receptor multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of OSMR mRNA CTD PMID:24690739 NCBI chr 2:55,907,119...55,961,373
Ensembl chr 2:55,907,132...55,961,262
JBrowse link
G P3h3 prolyl 3-hydroxylase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of P3H3 mRNA CTD PMID:24690739 NCBI chr 4:157,646,238...157,662,035 JBrowse link
G P3h4 prolyl 3-hydroxylase family member 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of P3H4 mRNA CTD PMID:24690739 NCBI chr10:85,338,158...85,345,108
Ensembl chr10:85,338,161...85,345,093
JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase increases activity EXP Disulfiram results in increased activity of PAM protein CTD PMID:8246921 PMID:10347250 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO [Copper co-treated with Disulfiram] results in increased cleavage of PARP1 protein; [Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein; [Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein; Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein]
Disulfiram results in increased cleavage of PARP1 protein
CTD PMID:17079463 PMID:19789329 PMID:23033007 PMID:24193513 PMID:24690739 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PCK2 mRNA CTD PMID:24690739 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283
JBrowse link
G Pcnx4 pecanex 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PCNX4 mRNA CTD PMID:24690739 NCBI chr 6:91,125,063...91,170,423 JBrowse link
G Pde5a phosphodiesterase 5A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDE5A mRNA CTD PMID:24690739 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701
JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDGFRB mRNA CTD PMID:24690739 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pdlim5 PDZ and LIM domain 5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDLIM5 mRNA CTD PMID:24690739 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
JBrowse link
G Pdpn podoplanin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PDPN protein
[Disulfiram binds to Copper] which results in increased expression of and results in increased phosphorylation of and results in increased ubiquitination of PDPN protein
CTD PMID:24690739 NCBI chr 5:155,601,691...155,635,656
Ensembl chr 5:155,601,691...155,635,656
JBrowse link
G Pdrg1 p53 and DNA damage regulated 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PDRG1 mRNA CTD PMID:24690739 NCBI chr 3:141,477,561...141,483,730
Ensembl chr 3:141,476,501...141,483,858
Ensembl chr 3:141,476,501...141,483,858
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Disulfiram results in increased expression of PGD mRNA CTD PMID:20566472 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Phlda2 pleckstrin homology-like domain, family A, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PHLDA2 mRNA CTD PMID:24690739 NCBI chr 1:198,696,897...198,699,292
Ensembl chr 1:198,696,897...198,697,836
JBrowse link
G Phldb2 pleckstrin homology-like domain, family B, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PHLDB2 mRNA CTD PMID:24690739 NCBI chr11:54,859,173...55,078,212
Ensembl chr11:54,859,135...55,078,467
JBrowse link
G Pigq phosphatidylinositol glycan anchor biosynthesis, class Q multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PIGQ mRNA CTD PMID:24690739 NCBI chr10:14,942,571...14,958,584
Ensembl chr10:14,942,577...14,958,584
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PIK3IP1 mRNA CTD PMID:24690739 NCBI chr14:78,203,539...78,216,616
Ensembl chr14:78,204,053...78,216,608
JBrowse link
G Pip4k2a phosphatidylinositol-5-phosphate 4-kinase type 2 alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PIP4K2A mRNA CTD PMID:24690739 NCBI chr17:81,496,669...81,668,180 JBrowse link
G Plod2 procollagen lysine, 2-oxoglutarate 5-dioxygenase 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLOD2 mRNA CTD PMID:24690739 NCBI chr 8:93,084,548...93,167,255
Ensembl chr 8:93,084,513...93,167,255
JBrowse link
G Plpbp pyridoxal phosphate binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PLPBP mRNA CTD PMID:24690739 NCBI chr16:65,003,292...65,014,886
Ensembl chr16:65,002,223...65,014,886
JBrowse link
G Plscr4 phospholipid scramblase 4 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLSCR4 mRNA CTD PMID:24690739 NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:92,987,381...93,026,049
JBrowse link
G Plxnb2 plexin B2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PLXNB2 mRNA CTD PMID:24690739 NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330
JBrowse link
G Pnldc1 PARN like ribonuclease domain containing exonuclease 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PNLDC1 mRNA CTD PMID:24690739 NCBI chr 1:47,843,224...47,861,675
Ensembl chr 1:47,843,224...47,861,674
JBrowse link
G Pnma2 PNMA family member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PNMA2 mRNA CTD PMID:24690739 NCBI chr15:41,111,942...41,119,649
Ensembl chr15:41,112,009...41,121,427
JBrowse link
G Polr2c RNA polymerase II subunit C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POLR2C mRNA CTD PMID:24690739 NCBI chr19:10,158,153...10,164,935
Ensembl chr19:10,157,823...10,164,945
JBrowse link
G Polr2m RNA polymerase II subunit M multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POLR2M mRNA CTD PMID:24690739 NCBI chr 8:72,131,992...72,139,423 JBrowse link
G Pomc proopiomelanocortin decreases expression EXP Disulfiram results in decreased expression of POMC protein alternative form CTD PMID:8246921 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664
JBrowse link
G Pop4 POP4 homolog, ribonuclease P/MRP subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of POP4 mRNA CTD PMID:24690739 NCBI chr 1:90,960,026...90,968,360
Ensembl chr 1:90,960,022...90,968,443
JBrowse link
G Postn periostin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of POSTN mRNA CTD PMID:24690739 NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression
multiple interactions
ISO Disulfiram affects the expression of PPARG mRNA
Disulfiram binds to and results in increased activity of PPARG protein
CTD PMID:32712770 PMID:33049310 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppia peptidylprolyl isomerase A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPIA mRNA CTD PMID:24690739 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP1R15A mRNA CTD PMID:24690739 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171
JBrowse link
G Ppp1r3c protein phosphatase 1, regulatory subunit 3C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP1R3C mRNA CTD PMID:24690739 NCBI chr 1:234,460,958...234,465,961
Ensembl chr 1:234,460,652...234,465,961
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PPP2R2B mRNA CTD PMID:24690739 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
JBrowse link
G Prok2 prokineticin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PROK2 mRNA CTD PMID:24690739 NCBI chr 4:132,346,681...132,361,754
Ensembl chr 4:132,347,103...132,361,385
JBrowse link
G Prss8 serine protease 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PRSS8 mRNA CTD PMID:24690739 NCBI chr 1:182,536,229...182,540,745
Ensembl chr 1:182,536,229...182,540,815
JBrowse link
G Psat1 phosphoserine aminotransferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PSAT1 mRNA CTD PMID:24690739 NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682
JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PSMC4 mRNA CTD PMID:24690739 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494
JBrowse link
G Pspn persephin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PSPN mRNA CTD PMID:24690739 NCBI chr 9:1,841,105...1,841,663
Ensembl chr 9:1,840,896...1,854,327
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO [Copper co-treated with Disulfiram] results in decreased expression of PTEN protein CTD PMID:20424113 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PTGES3 mRNA CTD PMID:24690739 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084
JBrowse link
G Ptgr1 prostaglandin reductase 1 increases expression ISO Disulfiram results in increased expression of PTGR1 mRNA CTD PMID:20566472 NCBI chr 5:73,784,000...73,802,624
Ensembl chr 5:73,784,009...73,802,666
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP Disulfiram results in decreased expression of PTGS2 mRNA CTD PMID:10418820 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptma prothymosin alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of PTMA mRNA CTD PMID:24690739 NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333
JBrowse link
G Ptx3 pentraxin 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of PTX3 mRNA CTD PMID:24690739 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323
JBrowse link
G Rab5c RAB5C, member RAS oncogene family multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAB5C mRNA CTD PMID:24690739 NCBI chr10:85,642,553...85,666,142
Ensembl chr10:85,642,809...85,666,103
JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAC1 mRNA CTD PMID:24690739 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
JBrowse link
G Rai2 retinoic acid induced 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAI2 mRNA CTD PMID:24690739 NCBI chr  X:32,948,656...33,011,222
Ensembl chr  X:32,948,656...33,011,264
JBrowse link
G Ramac RNA guanine-7 methyltransferase activating subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RAMAC mRNA CTD PMID:24690739 NCBI chr 1:135,708,529...135,714,417
Ensembl chr 1:135,708,535...135,722,151
JBrowse link
G Rasa1 RAS p21 protein activator 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RASA1 mRNA CTD PMID:24690739 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
JBrowse link
G Rasd1 ras related dexamethasone induced 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RASD1 mRNA CTD PMID:24690739 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186
JBrowse link
G Rasl11b RAS-like family 11 member B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RASL11B mRNA CTD PMID:24690739 NCBI chr14:34,014,924...34,019,146
Ensembl chr14:34,014,509...34,019,152
JBrowse link
G Rbis ribosomal biogenesis factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBIS mRNA CTD PMID:24690739 NCBI chr 2:86,981,314...86,997,352
Ensembl chr 2:86,991,315...87,041,339
JBrowse link
G Rbm18 RNA binding motif protein 18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBM18 mRNA CTD PMID:24690739 NCBI chr 3:19,467,333...19,487,171
Ensembl chr 3:19,467,335...19,487,178
JBrowse link
G Rbm48 RNA binding motif protein 48 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RBM48 mRNA CTD PMID:24690739 NCBI chr 4:30,559,063...30,569,409
Ensembl chr 4:30,559,087...30,569,406
JBrowse link
G Rep15 RAB15 effector protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of REP15 mRNA CTD PMID:24690739 NCBI chr 4:179,951,935...179,953,008
Ensembl chr 4:179,951,935...179,953,008
JBrowse link
G Rftn1 raftlin lipid raft linker 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RFTN1 mRNA CTD PMID:24690739 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084
JBrowse link
G Rftn2 raftlin family member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RFTN2 mRNA CTD PMID:24690739 NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810
JBrowse link
G Rgcc regulator of cell cycle multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGCC mRNA CTD PMID:24690739 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141
JBrowse link
G RGD1306746 similar to Hypothetical protein MGC25529 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C2ORF42 mRNA CTD PMID:24690739 NCBI chr 4:118,887,688...118,916,808
Ensembl chr 4:118,888,112...118,916,936
JBrowse link
G RGD1310553 similar to expressed sequence AI597479 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C2ORF49 mRNA CTD PMID:24690739 NCBI chr 9:45,371,396...45,382,123
Ensembl chr 9:45,371,430...45,382,120
JBrowse link
G RGD1564664 similar to LOC387763 protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C11ORF96 mRNA CTD PMID:24690739 NCBI chr 3:79,920,131...79,921,523
Ensembl chr 3:79,920,129...79,921,523
JBrowse link
G RGD1565784 RGD1565784 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of C16ORF91 mRNA CTD PMID:24690739 NCBI chr10:14,202,217...14,203,519
Ensembl chr10:14,202,243...14,204,029
JBrowse link
G Rgs11 regulator of G-protein signaling 11 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RGS11 mRNA CTD PMID:24690739 NCBI chr10:15,222,803...15,231,060
Ensembl chr10:15,222,803...15,231,060
JBrowse link
G Rgs16 regulator of G-protein signaling 16 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGS16 mRNA CTD PMID:24690739 NCBI chr13:65,887,788...65,891,232
Ensembl chr13:65,887,530...65,892,857
JBrowse link
G Rgs2 regulator of G-protein signaling 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RGS2 mRNA CTD PMID:24690739 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
JBrowse link
G Rhbdf1 rhomboid 5 homolog 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RHBDF1 mRNA CTD PMID:24690739 NCBI chr10:15,406,832...15,419,765
Ensembl chr10:15,406,859...15,419,763
JBrowse link
G Rhbdf2 rhomboid 5 homolog 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RHBDF2 mRNA CTD PMID:24690739 NCBI chr10:101,833,157...101,860,283
Ensembl chr10:101,833,157...101,860,283
JBrowse link
G Rhob ras homolog family member B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RHOB mRNA CTD PMID:24690739 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
JBrowse link
G Rnf207 ring finger protein 207 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RNF207 mRNA CTD PMID:24690739 NCBI chr 5:162,815,351...162,828,325
Ensembl chr 5:162,815,357...162,828,375
JBrowse link
G Rpl23 ribosomal protein L23 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL23 mRNA CTD PMID:24690739 NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
JBrowse link
G Rpl29 ribosomal protein L29 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL29 mRNA CTD PMID:24690739 NCBI chr 8:107,068,929...107,070,963
Ensembl chr 8:107,068,480...107,070,914
JBrowse link
G Rpl38 ribosomal protein L38 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPL38 mRNA CTD PMID:24690739 NCBI chr10:99,701,330...99,705,004
Ensembl chr10:99,701,362...99,705,004
JBrowse link
G Rps15 ribosomal protein S15 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPS15 mRNA CTD PMID:24690739 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450
JBrowse link
G Rps7 ribosomal protein S7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RPS7 mRNA CTD PMID:24690739 NCBI chr 6:45,266,200...45,271,064 JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RRAD mRNA CTD PMID:24690739 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417
JBrowse link
G Rragd Ras-related GTP binding D multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RRAGD mRNA CTD PMID:24690739 NCBI chr 5:47,373,902...47,409,369
Ensembl chr 5:47,373,463...47,409,356
JBrowse link
G Rras RAS related multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RRAS mRNA CTD PMID:24690739 NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357
JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of RSAD2 mRNA CTD PMID:24690739 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of HLA-F mRNA CTD PMID:24690739 NCBI chr20:3,403,418...3,479,476 JBrowse link
G Runx2 RUNX family transcription factor 2 increases expression EXP Disulfiram results in increased expression of RUNX2 mRNA CTD PMID:24496638 NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167
JBrowse link
G Rybp RING1 and YY1 binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of RYBP mRNA CTD PMID:24690739 NCBI chr 4:132,876,361...132,927,580
Ensembl chr 4:132,876,361...132,928,316
JBrowse link
G Sap18 Sin3A associated protein 18 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAP18 mRNA CTD PMID:24690739 NCBI chr15:31,943,228...31,947,534
Ensembl chr15:31,943,230...31,950,038
JBrowse link
G Sar1b secretion associated, Ras related GTPase 1B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAR1B mRNA CTD PMID:24690739 NCBI chr10:36,024,443...36,054,067
Ensembl chr10:36,024,382...36,054,066
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SAT1 mRNA CTD PMID:24690739 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813
JBrowse link
G Sbds SBDS, ribosome maturation factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SBDS mRNA CTD PMID:24690739 NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649
JBrowse link
G Scarf2 scavenger receptor class F, member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SCARF2 mRNA CTD PMID:24690739 NCBI chr11:83,175,956...83,187,415
Ensembl chr11:83,175,963...83,187,348
JBrowse link
G Sec61b SEC61 translocon subunit beta multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SEC61B mRNA CTD PMID:24690739 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804
JBrowse link
G Sel1l3 SEL1L family member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SEL1L3 mRNA CTD PMID:24690739 NCBI chr14:57,775,515...57,882,076
Ensembl chr14:57,775,501...57,882,644
JBrowse link
G Sem1 SEM1 26S proteasome subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SEM1 mRNA CTD PMID:24690739 NCBI chr 4:34,671,848...34,692,005
Ensembl chr 4:34,671,848...34,692,005
JBrowse link
G Sertad1 SERTA domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SERTAD1 mRNA CTD PMID:24690739 NCBI chr 1:82,775,692...82,778,961
Ensembl chr 1:82,775,252...82,779,091
JBrowse link
G Sf3b4 splicing factor 3b, subunit 4 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SF3B4 mRNA CTD PMID:24690739 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959
JBrowse link
G Sgta small glutamine rich tetratricopeptide repeat co-chaperone alpha multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SGTA mRNA CTD PMID:24690739 NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
JBrowse link
G Sh3pxd2a SH3 and PX domains 2A multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SH3PXD2A mRNA CTD PMID:24690739 NCBI chr 1:246,153,660...246,359,806
Ensembl chr 1:246,160,502...246,360,166
JBrowse link
G Sik1 salt-inducible kinase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIK1 mRNA CTD PMID:24690739 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIRT1 mRNA CTD PMID:24690739 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Sirt6 sirtuin 6 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SIRT6 mRNA CTD PMID:24690739 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Ski SKI proto-oncogene multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SKI mRNA CTD PMID:24690739 NCBI chr 5:165,713,525...165,782,134
Ensembl chr 5:165,714,093...165,782,733
JBrowse link
G Skil SKI-like proto-oncogene multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SKIL mRNA CTD PMID:24690739 NCBI chr 2:112,247,047...112,275,176
Ensembl chr 2:112,247,051...112,275,080
JBrowse link
G Slc16a10 solute carrier family 16 member 10 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC16A10 mRNA CTD PMID:24690739 NCBI chr20:43,454,819...43,567,839
Ensembl chr20:43,459,709...43,567,839
JBrowse link
G Slc25a37 solute carrier family 25 member 37 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC25A37 mRNA CTD PMID:24690739 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199
JBrowse link
G Slc30a1 solute carrier family 30 member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC30A1 mRNA CTD PMID:24690739 NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910
JBrowse link
G Slc44a1 solute carrier family 44 member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC44A1 mRNA CTD PMID:24690739 NCBI chr 5:68,061,941...68,241,912
Ensembl chr 5:68,063,618...68,241,909
JBrowse link
G Slc44a2 solute carrier family 44 member 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC44A2 mRNA CTD PMID:24690739 NCBI chr 8:19,870,867...19,905,345
Ensembl chr 8:19,870,888...19,905,342
JBrowse link
G Slc6a9 solute carrier family 6 member 9 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC6A9 mRNA CTD PMID:24690739 NCBI chr 5:131,374,562...131,408,733
Ensembl chr 5:131,374,542...131,408,728
JBrowse link
G Slc7a1 solute carrier family 7 member 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SLC7A1 mRNA CTD PMID:24690739 NCBI chr12:6,628,214...6,703,849
Ensembl chr12:6,628,007...6,703,849
JBrowse link
G Slc7a6os solute carrier family 7, member 6 opposite strand multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLC7A6OS mRNA CTD PMID:24690739 NCBI chr19:34,101,978...34,110,666
Ensembl chr19:34,101,982...34,110,651
JBrowse link
G Slfn13 schlafen family member 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLFN11 mRNA CTD PMID:24690739 NCBI chr10:67,909,105...67,955,912
Ensembl chr10:67,909,106...67,925,383
JBrowse link
G Slu7 SLU7 homolog, splicing factor multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SLU7 mRNA CTD PMID:24690739 NCBI chr10:27,908,325...27,923,784
Ensembl chr10:27,908,396...27,923,349
JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SMAD3 mRNA CTD PMID:24690739 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smox spermine oxidase multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SMOX mRNA CTD PMID:24690739 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710
JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNAI1 mRNA CTD PMID:24690739 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snip1 Smad nuclear interacting protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNIP1 mRNA CTD PMID:24690739 NCBI chr 5:137,328,371...137,335,846
Ensembl chr 5:137,328,371...137,335,845
JBrowse link
G Snrpb2 small nuclear ribonucleoprotein polypeptide B2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SNRPB2 mRNA CTD PMID:24690739 NCBI chr 3:130,399,239...130,408,821
Ensembl chr 3:130,399,248...130,408,812
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases activity
ISO Disulfiram results in increased expression of SOD1 mRNA
Disulfiram results in decreased activity of SOD1 protein
CTD PMID:19016906 PMID:20566472 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
ISO Disulfiram results in increased expression of SOD2 mRNA
[Disulfiram co-treated with Zinc Sulfate] results in increased expression of SOD2 mRNA
CTD PMID:20566472 PMID:32712770 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 increases expression ISO Disulfiram results in increased expression of SOD3 mRNA CTD PMID:20566472 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Sox8 SRY-box transcription factor 8 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SOX8 mRNA CTD PMID:24690739 NCBI chr10:14,584,829...14,589,818
Ensembl chr10:14,584,829...14,589,818
JBrowse link
G Spata20 spermatogenesis associated 20 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPATA20 mRNA CTD PMID:24690739 NCBI chr10:79,427,525...79,435,472
Ensembl chr10:79,427,528...79,434,368
JBrowse link
G Spire1 spire-type actin nucleation factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPIRE1 mRNA CTD PMID:24690739 NCBI chr18:61,041,290...61,171,670
Ensembl chr18:61,041,290...61,171,899
JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression ISO Disulfiram results in increased expression of SPSB1 mRNA CTD PMID:20566472 NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468
JBrowse link
G Sptbn1 spectrin, beta, non-erythrocytic 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SPTBN1 mRNA CTD PMID:24690739 NCBI chr14:103,842,684...104,008,507
Ensembl chr14:103,842,684...104,008,507
JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SPTY2D1 mRNA CTD PMID:24690739 NCBI chr 1:97,531,495...97,549,633 JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SREBF1 mRNA CTD PMID:24690739 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Disulfiram results in increased expression of SRXN1 mRNA CTD PMID:20566472 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Stc2 stanniocalcin 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of STC2 mRNA CTD PMID:24690739 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973
JBrowse link
G Steep1 STING1 ER exit protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of STEEP1 mRNA CTD PMID:24690739 NCBI chr  X:116,087,626...116,114,159
Ensembl chr  X:116,060,929...116,114,159
JBrowse link
G Stx3 syntaxin 3 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of STX3 mRNA CTD PMID:24690739 NCBI chr 1:208,617,018...208,686,240
Ensembl chr 1:208,639,115...208,685,805
JBrowse link
G Sulf1 sulfatase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SULF1 mRNA; [Disulfiram binds to Copper] which results in increased expression of SULF1 protein CTD PMID:24690739 NCBI chr 5:6,362,896...6,526,174
Ensembl chr 5:6,362,911...6,525,584
JBrowse link
G Sumo2 small ubiquitin-like modifier 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SUMO2 mRNA CTD PMID:24690739 NCBI chr10:100,771,941...100,784,503 JBrowse link
G Sun1 Sad1 and UNC84 domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SUN1 mRNA CTD PMID:24690739 NCBI chr12:15,396,378...15,441,277
Ensembl chr12:15,396,381...15,441,571
JBrowse link
G Sun2 Sad1 and UNC84 domain containing 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of SUN2 mRNA CTD PMID:24690739 NCBI chr 7:111,275,374...111,292,565
Ensembl chr 7:111,275,380...111,292,553
JBrowse link
G Supt4h1 SPT4 homolog, DSIF elongation factor subunit multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SUPT4H1 mRNA CTD PMID:24690739 NCBI chr10:72,539,323...72,545,582
Ensembl chr10:72,539,382...72,545,831
JBrowse link
G Synj1 synaptojanin 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SYNJ1 mRNA CTD PMID:24690739 NCBI chr11:30,192,629...30,269,277
Ensembl chr11:30,192,629...30,269,220
JBrowse link
G Szrd1 SUZ RNA binding domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of SZRD1 mRNA CTD PMID:24690739 NCBI chr 5:153,418,748...153,443,286
Ensembl chr 5:153,418,748...153,443,252
JBrowse link
G Taf13 TATA-box binding protein associated factor 13 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAF13 mRNA CTD PMID:24690739 NCBI chr 2:196,205,219...196,215,882
Ensembl chr 2:196,205,243...196,215,878
JBrowse link
G Taf7 TATA-box binding protein associated factor 7 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAF7 mRNA CTD PMID:24690739 NCBI chr18:29,459,937...29,462,086
Ensembl chr18:29,452,943...29,462,134
JBrowse link
G Tamalin trafficking regulator and scaffold protein tamalin multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAMALIN mRNA CTD PMID:24690739 NCBI chr 7:132,338,900...132,359,519
Ensembl chr 7:132,338,900...132,346,666
JBrowse link
G Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TANC1 mRNA CTD PMID:24690739 NCBI chr 3:44,099,387...44,335,478
Ensembl chr 3:44,134,016...44,331,627
JBrowse link
G Tap2 transporter 2, ATP binding cassette subfamily B member multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TAP2 mRNA CTD PMID:24690739 NCBI chr20:4,636,347...4,650,387
Ensembl chr20:4,636,357...4,650,407
JBrowse link
G Tapbp TAP binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TAPBP mRNA CTD PMID:24690739 NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP [Ethanol co-treated with Disulfiram] results in increased activity of TAT protein CTD PMID:9591243 NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
JBrowse link
G Tcea2 transcription elongation factor A2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TCEA2 mRNA CTD PMID:24690739 NCBI chr 3:168,796,244...168,804,125
Ensembl chr 3:168,796,331...168,804,116
JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TCP1 mRNA CTD PMID:24690739 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Tent5b terminal nucleotidyltransferase 5B multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TENT5B mRNA CTD PMID:24690739 NCBI chr 5:145,695,358...145,702,668
Ensembl chr 5:145,695,362...145,706,073
JBrowse link
G Tent5c terminal nucleotidyltransferase 5C multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TENT5C mRNA CTD PMID:24690739 NCBI chr 2:187,853,026...187,875,260
Ensembl chr 2:187,853,024...187,894,744
JBrowse link
G Tfip11 tuftelin interacting protein 11 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TFIP11 mRNA CTD PMID:24690739 NCBI chr12:44,299,619...44,311,851
Ensembl chr12:44,299,622...44,311,855
JBrowse link
G Tgfb1 transforming growth factor, beta 1 decreases activity ISO Disulfiram results in decreased activity of TGFB1 protein CTD PMID:31652400 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Thap1 THAP domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of THAP1 mRNA CTD PMID:24690739 NCBI chr16:65,905,348...65,909,942
Ensembl chr16:65,904,230...65,909,942
JBrowse link
G Them6 thioesterase superfamily member 6 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of THEM6 mRNA CTD PMID:24690739 NCBI chr 7:106,606,570...106,609,747
Ensembl chr 7:106,606,570...106,609,746
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Disulfiram binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
JBrowse link
G Ticam2 toll-like receptor adaptor molecule 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TICAM2 mRNA CTD PMID:24690739 NCBI chr18:39,289,902...39,311,462
Ensembl chr18:39,294,453...39,311,462
JBrowse link
G Tmem167a transmembrane protein 167A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TMEM167A mRNA CTD PMID:24690739 NCBI chr 2:21,197,728...21,216,746
Ensembl chr 2:21,197,786...21,212,099
JBrowse link
G Tmem175 transmembrane protein 175 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM175 mRNA CTD PMID:24690739 NCBI chr14:1,073,410...1,089,764
Ensembl chr14:1,073,523...1,089,819
JBrowse link
G Tmem208 transmembrane protein 208 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TMEM208 mRNA CTD PMID:24690739 NCBI chr19:33,203,587...33,206,287
Ensembl chr19:33,203,587...33,212,183
JBrowse link
G Tmem35b transmembrane protein 35B multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM35B mRNA CTD PMID:24690739 NCBI chr 5:139,446,317...139,449,947
Ensembl chr 5:139,444,399...139,449,947
JBrowse link
G Tmem42 transmembrane protein 42 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM42 mRNA CTD PMID:24690739 NCBI chr 8:122,674,793...122,677,290
Ensembl chr 8:122,674,070...122,677,276
JBrowse link
G Tmem43 transmembrane protein 43 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM43 mRNA CTD PMID:24690739 NCBI chr 4:123,977,680...123,992,823
Ensembl chr 4:123,977,625...123,992,825
JBrowse link
G Tmem44 transmembrane protein 44 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TMEM44 mRNA CTD PMID:24690739 NCBI chr11:70,181,120...70,216,958
Ensembl chr11:70,181,345...70,216,958
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases secretion
multiple interactions
EXP
ISO
Disulfiram results in decreased expression of TNF mRNA
Disulfiram results in increased secretion of TNF protein
[Disulfiram co-treated with Zinc Sulfate] inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Disulfiram promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
Disulfiram inhibits the reaction [[CCL5 protein binds to and results in increased activity of CCR5 protein] which results in increased secretion of TNF protein]
CTD PMID:10418820 PMID:19016906 PMID:32712770 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TNIP1 protein CTD PMID:24690739 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625
JBrowse link
G Tnip2 TNFAIP3 interacting protein 2 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TNIP2 protein CTD PMID:24690739 NCBI chr14:76,228,283...76,246,609
Ensembl chr14:76,228,371...76,275,265
JBrowse link
G Tns3 tensin 3 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TNS3 mRNA CTD PMID:24690739 NCBI chr14:83,173,649...83,405,671
Ensembl chr14:83,173,649...83,405,998
JBrowse link
G Tprkb Tp53rk binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TPRKB mRNA CTD PMID:24690739 NCBI chr 4:118,342,910...118,357,908
Ensembl chr 4:118,342,945...118,357,901
JBrowse link
G Tpsab1 tryptase alpha/beta 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TPSAB1 mRNA CTD PMID:24690739 NCBI chr10:14,360,396...14,362,811
Ensembl chr10:14,360,396...14,362,811
JBrowse link
G Tra2b transformer 2 beta homolog multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TRA2B mRNA CTD PMID:24690739 NCBI chr11:78,788,880...78,807,252
Ensembl chr11:78,788,884...78,807,249
JBrowse link
G Trabd TraB domain containing multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TRABD mRNA CTD PMID:24690739 NCBI chr 7:120,155,042...120,166,015
Ensembl chr 7:120,155,042...120,166,015
JBrowse link
G Trh thyrotropin releasing hormone multiple interactions
increases expression
decreases expression
EXP Dexamethasone promotes the reaction [Disulfiram results in decreased expression of TRH protein]
Disulfiram results in increased expression of TRH mRNA alternative form
CTD PMID:9681491 NCBI chr 4:124,742,111...124,777,094
Ensembl chr 4:124,742,111...124,744,637
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions
decreases secretion
EXP Dexamethasone promotes the reaction [Disulfiram results in decreased secretion of TSHB protein] CTD PMID:9681491 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559
JBrowse link
G Tspyl2 TSPY-like 2 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TSPYL2 mRNA CTD PMID:24690739 NCBI chr  X:21,439,478...21,445,208
Ensembl chr  X:21,439,478...21,445,089
JBrowse link
G Ttc13 tetratricopeptide repeat domain 13 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of TTC13 mRNA CTD PMID:24690739 NCBI chr19:52,637,431...52,692,196
Ensembl chr19:52,637,431...52,692,198
JBrowse link
G Ttf1 transcription termination factor 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TTF1 mRNA CTD PMID:24690739 NCBI chr 3:12,384,626...12,409,257
Ensembl chr 3:12,384,655...12,409,257
JBrowse link
G Tuba4a tubulin, alpha 4A multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TUBA4A mRNA CTD PMID:24690739 NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
JBrowse link
G Tubb2a tubulin, beta 2A class IIa multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TUBB2A mRNA CTD PMID:24690739 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Tubb2b tubulin, beta 2B class IIb multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TUBB2B mRNA CTD PMID:24690739 NCBI chr17:30,747,734...30,750,781
Ensembl chr17:30,747,734...30,750,638
JBrowse link
G Tubb3 tubulin, beta 3 class III multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TUBB3 mRNA CTD PMID:24690739 NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
JBrowse link
G Txn2 thioredoxin 2 increases expression ISO Disulfiram results in increased expression of TXN2 mRNA CTD PMID:20566472 NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359
JBrowse link
G Txnl1 thioredoxin-like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of TXNL1 mRNA CTD PMID:24690739 NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Disulfiram results in increased expression of TXNRD1 mRNA CTD PMID:20566472 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Txnrd2 thioredoxin reductase 2 increases expression ISO Disulfiram results in increased expression of TXNRD2 mRNA CTD PMID:20566472 NCBI chr11:82,519,996...82,568,156
Ensembl chr11:82,519,999...82,568,156
JBrowse link
G Ubfd1 ubiquitin family domain containing 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UBFD1 mRNA CTD PMID:24690739 NCBI chr 1:176,626,003...176,640,993
Ensembl chr 1:176,625,657...176,640,993
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO Disulfiram results in increased expression of UGT1A6 mRNA CTD PMID:20566472 NCBI chr 9:88,747,229...88,808,465 JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of ULK1 mRNA CTD PMID:24690739 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UQCRB mRNA CTD PMID:24690739 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UQCRH mRNA CTD PMID:24690739 NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
JBrowse link
G Uspl1 ubiquitin specific peptidase like 1 multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of USPL1 mRNA CTD PMID:24690739 NCBI chr12:5,823,460...5,850,470
Ensembl chr12:5,823,359...5,850,366
JBrowse link
G Utp11 UTP11, small subunit processome component multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UTP11 mRNA CTD PMID:24690739 NCBI chr 5:136,931,279...136,946,164
Ensembl chr 5:136,931,008...136,946,191
JBrowse link
G Utp3 UTP3, small subunit processome component multiple interactions ISO [Disulfiram binds to Copper] which results in decreased expression of UTP3 mRNA CTD PMID:24690739 NCBI chr14:19,515,716...19,517,370
Ensembl chr14:19,515,669...19,517,396
JBrowse link
G Vcan versican multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of VCAN mRNA CTD PMID:24690739 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
JBrowse link
G Vcl vinculin multiple interactions ISO [Disulfiram binds to Copper] which results in increased expression of VCL mRNA CTD PMID:24690739 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606