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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:antipsychotic agent
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Accession:CHEBI:35476 term browser browse the term
Definition:Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
Synonyms:related_synonym: Neuroleptikum;   antipsychotic agents;   antipsychotic drug;   antipsychotic drugs;   antipsychotics;   antipsychotiques;   grosser Tranquilizer;   major tranquilizers;   major tranquilizing agents;   neuroleptic;   neuroleptic agents;   neuroleptics;   neuroleptique;   neuroleptiques


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(Z)-chlorprothixene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Chlorprothixene inhibits the reaction [(2-(2',6'-dimethoxy)phenoxyethylamino)methylbenzo-1,4-dioxane binds to HTR1A protein] CTD PMID:2891550 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Chlorprothixene results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Prl prolactin increases secretion ISO Chlorprothixene results in increased secretion of PRL protein CTD PMID:10525070 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
acepromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO Acepromazine results in increased activity of ACHE protein CTD PMID:29614332 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
acetophenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO acetophenazine binds to and results in decreased activity of AR protein CTD PMID:17606915 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
amisulpride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Amisulpride results in decreased activity of ACHE protein CTD PMID:33844597 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Drd2 dopamine receptor D2 affects binding EXP Amisulpride binds to DRD2 protein CTD PMID:12191584 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Prl prolactin increases secretion
increases expression
multiple interactions		 ISO
EXP		 Amisulpride results in increased secretion of PRL protein
Amisulpride results in increased expression of PRL protein
Bromocriptine inhibits the reaction [Amisulpride results in increased secretion of PRL protein]; carmoxirole inhibits the reaction [Amisulpride results in increased secretion of PRL protein]		 CTD PMID:12106810 PMID:14966260 PMID:14997280 PMID:15665803 PMID:16938372 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 decreases expression ISO Amisulpride results in decreased expression of VIPR2 mRNA CTD PMID:27900577 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597 		JBrowse link
amperozide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO amperozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:19583963 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
aripiprazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain decreases expression EXP Aripiprazole results in decreased expression of ACADL mRNA CTD PMID:17868501 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220 		JBrowse link
G Adora2a adenosine A2a receptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ADORA2A mRNA CTD PMID:31476115 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Arpc1b actin related protein 2/3 complex, subunit 1B decreases expression EXP Aripiprazole results in decreased expression of ARPC1B mRNA CTD PMID:17868501 NCBI chr12:9,482,176...9,495,772
Ensembl chr12:9,480,831...9,495,747 		JBrowse link
G Bcl10 BCL10, immune signaling adaptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of BCL10 mRNA CTD PMID:31476115 NCBI chr 2:234,840,880...234,850,520
Ensembl chr 2:234,840,858...234,850,523 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of BCL2L1 mRNA CTD PMID:31476115 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl6 BCL6, transcription repressor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of BCL6 mRNA CTD PMID:31476115 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389 		JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of BID mRNA CTD PMID:31476115 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G C1r complement C1r multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in decreased expression of C1R mRNA] CTD PMID:31476115 NCBI chr 4:157,412,718...157,423,483
Ensembl chr 4:157,412,692...157,423,484 		JBrowse link
G C2 complement C2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of C2 mRNA CTD PMID:31476115 NCBI chr20:3,951,474...3,970,376
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cbx7 chromobox 7 decreases expression
increases expression		 EXP Aripiprazole results in decreased expression of CBX7 mRNA
Aripiprazole results in increased expression of CBX7 mRNA		 CTD PMID:17868501 NCBI chr 7:111,460,656...111,479,231
Ensembl chr 7:111,460,656...111,477,973 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL19 mRNA CTD PMID:31476115 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL2 mRNA CTD PMID:31476115 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL20 mRNA CTD PMID:31476115 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl22 C-C motif chemokine ligand 22 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of CCL22 mRNA] CTD PMID:31476115 NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL3 mRNA CTD PMID:31476115 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL4 mRNA CTD PMID:31476115 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCL5 mRNA CTD PMID:31476115 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CCR3 mRNA CTD PMID:31476115 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Cd274 CD274 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD274 mRNA CTD PMID:31476115 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd33 CD33 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD33 mRNA CTD PMID:31476115 NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149 		JBrowse link
G Cd44 CD44 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD44 mRNA CTD PMID:31476115 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd70 Cd70 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD70 mRNA CTD PMID:31476115 NCBI chr 9:2,006,563...2,009,715
Ensembl chr 9:2,006,563...2,009,715 		JBrowse link
G Cd83 CD83 molecule multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CD83 mRNA CTD PMID:31476115 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cdh5 cadherin 5 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of CDH5 mRNA] CTD PMID:31476115 NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CDKN1A mRNA CTD PMID:31476115 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CEBPB mRNA CTD PMID:31476115 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfb complement factor B multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CFB mRNA CTD PMID:31476115 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cldn5 claudin 5 decreases expression EXP Aripiprazole results in decreased expression of CLDN5 mRNA CTD PMID:17868501 NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992 		JBrowse link
G Cnr1 cannabinoid receptor 1 increases expression EXP Aripiprazole results in increased expression of CNR1 mRNA CTD PMID:17868501 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Aripiprazole results in increased expression of COMT mRNA CTD PMID:17868501 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Creb5 cAMP responsive element binding protein 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CREB5 mRNA CTD PMID:31476115 NCBI chr 4:82,393,091...82,794,320
Ensembl chr 4:82,393,730...82,790,325 		JBrowse link
G Crebbp CREB binding protein decreases expression EXP Aripiprazole results in decreased expression of CREBBP mRNA CTD PMID:17868501 NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888 		JBrowse link
G Crmp1 collapsin response mediator protein 1 increases expression EXP Aripiprazole results in increased expression of CRMP1 mRNA CTD PMID:17868501 NCBI chr14:73,509,933...73,556,192
Ensembl chr14:73,509,933...73,556,177 		JBrowse link
G Csf1 colony stimulating factor 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CSF1 mRNA CTD PMID:31476115 NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704 		JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CSF2 mRNA CTD PMID:31476115 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CSF3 mRNA CTD PMID:31476115 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CX3CL1 mRNA CTD PMID:31476115 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCL1 mRNA CTD PMID:31476115 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCL2 mRNA CTD PMID:31476115 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCL1 mRNA CTD PMID:31476115 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcr5 C-X-C motif chemokine receptor 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCR5 mRNA CTD PMID:31476115 NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893 		JBrowse link
G Cxcr6 C-X-C motif chemokine receptor 6 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CXCR6 mRNA CTD PMID:31476115 NCBI chr 8:123,434,417...123,439,568
Ensembl chr 8:123,416,325...123,439,526 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CYBB mRNA CTD PMID:31476115 NCBI chr  X:13,358,101...13,392,570
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyld CYLD lysine 63 deubiquitinase multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of CYLD mRNA CTD PMID:31476115 NCBI chr19:18,310,632...18,373,696
Ensembl chr19:18,314,019...18,373,658 		JBrowse link
G Ddr2 discoidin domain receptor tyrosine kinase 2 decreases expression EXP Aripiprazole results in decreased expression of DDR2 mRNA CTD PMID:17868501 NCBI chr13:82,193,623...82,318,229
Ensembl chr13:82,195,463...82,317,363 		JBrowse link
G Ddx50 DExD-box helicase 50 increases expression EXP Aripiprazole results in increased expression of DDX50 mRNA CTD PMID:17868501 NCBI chr20:30,561,623...30,591,324
Ensembl chr20:30,560,544...30,591,152 		JBrowse link
G Dnal4 dynein, axonemal, light chain 4 decreases expression EXP Aripiprazole results in decreased expression of DNAL4 mRNA CTD PMID:17868501 NCBI chr 7:111,312,424...111,325,283
Ensembl chr 7:111,312,427...111,325,283 		JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha increases expression EXP Aripiprazole results in increased expression of DNMT3A mRNA CTD PMID:17868501 NCBI chr 6:26,791,517...26,902,161
Ensembl chr 6:26,822,609...26,896,687 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP
ISO		 [Aripiprazole binds to and results in increased activity of DRD2 protein] which results in increased susceptibility to Methamphetamine CTD PMID:17069544 PMID:17327886 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dusp4 dual specificity phosphatase 4 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of DUSP4 mRNA CTD PMID:31476115 NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138 		JBrowse link
G Dusp6 dual specificity phosphatase 6 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of DUSP6 mRNA CTD PMID:31476115 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Ebi3 Epstein-Barr virus induced 3 multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of EBI3 mRNA] CTD PMID:31476115 NCBI chr 9:774,252...787,544
Ensembl chr 9:783,617...787,544 		JBrowse link
G Egr1 early growth response 1 increases expression EXP Aripiprazole results in increased expression of EGR1 mRNA; Aripiprazole results in increased expression of EGR1 protein CTD PMID:17868501 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 increases expression EXP Aripiprazole results in increased expression of EGR2 mRNA CTD PMID:17868501 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Egr4 early growth response 4 increases expression EXP Aripiprazole results in increased expression of EGR4 mRNA CTD PMID:17868501 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328 		JBrowse link
G Elane elastase, neutrophil expressed multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ELANE mRNA CTD PMID:31476115 NCBI chr 7:9,817,251...9,819,174
Ensembl chr 7:9,817,252...9,819,100 		JBrowse link
G Elavl2 ELAV like RNA binding protein 2 increases expression EXP Aripiprazole results in increased expression of ELAVL2 mRNA CTD PMID:17868501 NCBI chr 5:105,960,872...106,086,463
Ensembl chr 5:105,960,875...106,109,097 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ETS1 mRNA CTD PMID:31476115 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Exoc2 exocyst complex component 2 increases expression EXP Aripiprazole results in increased expression of EXOC2 mRNA CTD PMID:17868501 NCBI chr17:33,506,289...33,698,246
Ensembl chr17:33,506,338...33,693,289 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of F2RL1 mRNA] CTD PMID:31476115 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 multiple interactions
increases expression		 ISO [Aripiprazole co-treated with Ozone] results in increased expression of FEZ1 mRNA
Aripiprazole results in increased expression of FEZ1 mRNA		 CTD PMID:31476115 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683 		JBrowse link
G Fn1 fibronectin 1 decreases expression ISO Aripiprazole results in decreased expression of FN1 mRNA CTD PMID:31476115 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor decreases expression EXP Aripiprazole results in decreased expression of HBEGF mRNA CTD PMID:17868501 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Aripiprazole binds to and affects the activity of HTR1A protein; Aripiprazole binds to and results in increased activity of HTR1A protein CTD PMID:17069544 PMID:21823597 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
decreases response to substance
affects response to substance		 ISO Aripiprazole binds to and results in decreased activity of HTR2A protein; Aripiprazole binds to and results in increased activity of HTR2A protein; Aripiprazole inhibits the reaction [Ketanserin binds to HTR2A protein]
HTR2A gene SNP results in decreased susceptibility to Aripiprazole
HTR2A protein affects the susceptibility to Aripiprazole		 CTD PMID:16314884 PMID:21823597 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C multiple interactions ISO Aripiprazole binds to and affects the activity of HTR2C protein CTD PMID:21823597 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ICAM1 mRNA CTD PMID:31476115 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Icam4 intercellular adhesion molecule 4, Landsteiner-Wiener blood group multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ICAM4 mRNA CTD PMID:31476115 NCBI chr 8:19,566,075...19,567,171
Ensembl chr 8:19,566,075...19,567,171 		JBrowse link
G Icoslg inducible T-cell co-stimulator ligand multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ICOSLG mRNA CTD PMID:31476115 NCBI chr20:10,600,420...10,610,718
Ensembl chr20:10,600,420...10,610,703 		JBrowse link
G Ifnb1 interferon beta 1 increases expression
multiple interactions		 ISO Aripiprazole results in increased expression of IFNB1 mRNA
Aripiprazole promotes the reaction [Ozone results in increased expression of IFNB1 mRNA]		 CTD PMID:31476115 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of IFNG mRNA CTD PMID:31476115 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IFNGR1 mRNA CTD PMID:31476115 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Ikbke inhibitor of nuclear factor kappa B kinase subunit epsilon multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IKBKE mRNA CTD PMID:31476115 NCBI chr13:42,712,154...42,738,470
Ensembl chr13:42,712,159...42,737,143 		JBrowse link
G Il11 interleukin 11 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL11 mRNA CTD PMID:31476115 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1A mRNA CTD PMID:31476115 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1B mRNA CTD PMID:31476115 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1r2 interleukin 1 receptor type 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1R2 mRNA CTD PMID:31476115 NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725 		JBrowse link
G Il1rap interleukin 1 receptor accessory protein multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1RAP mRNA CTD PMID:31476115 NCBI chr11:74,062,999...74,199,530
Ensembl chr11:74,070,304...74,199,530 		JBrowse link
G Il1rapl2 interleukin 1 receptor accessory protein-like 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1RAPL2 mRNA CTD PMID:31476115 NCBI chr  X:100,961,509...102,271,753
Ensembl chr  X:100,961,812...102,271,753 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL1RL1 mRNA CTD PMID:31476115 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il23a interleukin 23 subunit alpha multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL23A mRNA CTD PMID:31476115 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923 		JBrowse link
G Il24 interleukin 24 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL24 mRNA CTD PMID:31476115 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il2rg interleukin 2 receptor subunit gamma multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of IL2RG mRNA CTD PMID:31476115 NCBI chr  X:66,395,330...66,399,026
Ensembl chr  X:66,392,542...66,399,823 		JBrowse link
G Il4r interleukin 4 receptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL4R mRNA CTD PMID:31476115 NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980 		JBrowse link
G Il5 interleukin 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL5 mRNA CTD PMID:31476115 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL6 mRNA; Aripiprazole promotes the reaction [Ozone results in increased expression of IL6 mRNA] CTD PMID:31476115 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il7r interleukin 7 receptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of IL7R mRNA CTD PMID:31476115 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Inpp5d inositol polyphosphate-5-phosphatase D multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of INPP5D mRNA CTD PMID:31476115 NCBI chr 9:88,287,680...88,392,748
Ensembl chr 9:88,287,677...88,392,746 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of IRAK2 mRNA] CTD PMID:31476115 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf8 interferon regulatory factor 8 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of IRF8 mRNA CTD PMID:31476115 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829 		JBrowse link
G Isg20 interferon stimulated exonuclease gene 20 increases expression
multiple interactions		 ISO Aripiprazole results in increased expression of ISG20 mRNA
[Aripiprazole co-treated with Ozone] results in increased expression of ISG20 mRNA		 CTD PMID:31476115 NCBI chr 1:132,829,303...132,837,027
Ensembl chr 1:132,815,123...132,837,027 		JBrowse link
G Itga2 integrin subunit alpha 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ITGA2 mRNA CTD PMID:31476115 NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481 		JBrowse link
G Itga5 integrin subunit alpha 5 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of ITGA5 mRNA CTD PMID:31476115 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Aripiprazole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Aripiprazole results in decreased activity of KCNH2 protein		 CTD PMID:21158687 PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 increases expression EXP Aripiprazole results in increased expression of KCNJ3 mRNA CTD PMID:17868501 NCBI chr 3:39,944,896...40,106,646
Ensembl chr 3:39,945,351...40,109,124 		JBrowse link
G Lif LIF, interleukin 6 family cytokine multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LIF mRNA CTD PMID:31476115 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lrrn3 leucine rich repeat neuronal 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LRRN3 mRNA CTD PMID:31476115 NCBI chr 6:58,489,060...58,520,322
Ensembl chr 6:58,489,010...58,520,330 		JBrowse link
G Lta lymphotoxin alpha multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LTA mRNA CTD PMID:31476115 NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859 		JBrowse link
G Ltb lymphotoxin beta multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LTB mRNA CTD PMID:31476115 NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of LYN mRNA CTD PMID:31476115 NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868 		JBrowse link
G Maob monoamine oxidase B increases expression EXP Aripiprazole results in increased expression of MAOB mRNA CTD PMID:17868501 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Mapk6 mitogen-activated protein kinase 6 increases expression EXP Aripiprazole results in increased expression of MAPK6 mRNA CTD PMID:17868501 NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of MAPKAPK2 mRNA CTD PMID:31476115 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of NFKB1 mRNA CTD PMID:31476115 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of NFKB2 mRNA] CTD PMID:31476115 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of NFKBIA mRNA CTD PMID:31476115 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of NLRP3 mRNA CTD PMID:31476115 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 multiple interactions
increases expression		 ISO [Aripiprazole co-treated with Ozone] results in increased expression of NOD2 mRNA
Aripiprazole results in increased expression of NOD2 mRNA		 CTD PMID:31476115 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Npdc1 neural proliferation, differentiation and control, 1 decreases expression EXP Aripiprazole results in decreased expression of NPDC1 mRNA CTD PMID:17868501 NCBI chr 3:8,220,446...8,226,446
Ensembl chr 3:8,213,663...8,226,866 		JBrowse link
G Nt5e 5' nucleotidase, ecto multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of NT5E mRNA CTD PMID:31476115 NCBI chr 8:89,271,046...89,314,918
Ensembl chr 8:89,270,696...89,314,881 		JBrowse link
G Ntm neurotrimin decreases expression EXP Aripiprazole results in decreased expression of NTM mRNA CTD PMID:17868501 NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:27,377,773...28,366,595 		JBrowse link
G Pdcd1lg2 programmed cell death 1 ligand 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PDCD1LG2 mRNA CTD PMID:31476115 NCBI chr 1:227,158,941...227,223,938
Ensembl chr 1:227,158,941...227,223,938 		JBrowse link
G Pdgfc platelet derived growth factor C multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of PDGFC mRNA CTD PMID:31476115 NCBI chr 2:166,316,870...166,493,449
Ensembl chr 2:166,316,803...166,493,433 		JBrowse link
G Pdp1 pyruvate dehydrogenase phosphatase catalytic subunit 1 increases expression EXP Aripiprazole results in increased expression of PDP1 mRNA CTD PMID:17868501 NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217 		JBrowse link
G Plau plasminogen activator, urokinase multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PLAU mRNA CTD PMID:31476115 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PLAUR mRNA CTD PMID:31476115 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pou2f2 POU class 2 homeobox 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of POU2F2 mRNA CTD PMID:31476115 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261 		JBrowse link
G Prg2 proteoglycan 2, pro eosinophil major basic protein multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PRG2 mRNA CTD PMID:31476115 NCBI chr 3:70,062,535...70,066,102
Ensembl chr 3:70,062,535...70,066,101 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PRKCD mRNA CTD PMID:31476115 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prl prolactin multiple interactions
increases secretion
decreases secretion
decreases expression		 ISO
EXP		 Aripiprazole inhibits the reaction [haloperidol decanoate results in increased expression of PRL protein]; Aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein]
Aripiprazole results in increased secretion of PRL protein
Aripiprazole results in decreased secretion of PRL protein
Aripiprazole inhibits the reaction [talipexole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Aripiprazole results in decreased secretion of PRL protein]
Aripiprazole results in decreased expression of PRL protein		 CTD PMID:8613910 PMID:17873694 PMID:19230981 PMID:19519261 PMID:19653986 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prodh proline dehydrogenase decreases expression EXP Aripiprazole results in decreased expression of PRODH mRNA CTD PMID:17868501 NCBI chr11:82,910,043...82,927,305
Ensembl chr11:82,910,137...82,927,305 		JBrowse link
G Psmc6 proteasome 26S subunit, ATPase 6 increases expression EXP Aripiprazole results in increased expression of PSMC6 mRNA CTD PMID:17868501 NCBI chr15:18,542,585...18,564,057
Ensembl chr15:18,542,563...18,564,055 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of PTGS2 mRNA CTD PMID:31476115 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pycard PYD and CARD domain containing multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of PYCARD mRNA CTD PMID:31476115 NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family increases expression EXP Aripiprazole results in increased expression of RAB3A mRNA CTD PMID:17868501 NCBI chr16:18,684,185...18,688,297
Ensembl chr16:18,684,188...18,688,336 		JBrowse link
G Rasd1 ras related dexamethasone induced 1 increases expression EXP Aripiprazole results in increased expression of RASD1 mRNA CTD PMID:17868501 NCBI chr10:44,766,451...44,775,773
Ensembl chr10:44,766,455...44,768,186 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of RELB mRNA CTD PMID:31476115 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Rig1 RNA sensor RIG-1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of RIGI mRNA CTD PMID:31476115 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 increases expression EXP Aripiprazole results in increased expression of SAE1 mRNA CTD PMID:17868501 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986 		JBrowse link
G Sbno2 strawberry notch homolog 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SBNO2 mRNA CTD PMID:31476115 NCBI chr 7:9,605,572...9,649,529
Ensembl chr 7:9,605,627...9,649,527 		JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SERPINB2 mRNA CTD PMID:31476115 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Sh2b2 SH2B adaptor protein 2 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of SH2B2 mRNA CTD PMID:31476115 NCBI chr12:20,427,057...20,456,845
Ensembl chr12:20,429,043...20,456,844 		JBrowse link
G Slamf6 SLAM family member 6 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SLAMF6 mRNA CTD PMID:31476115 NCBI chr13:84,384,561...84,405,300
Ensembl chr13:84,383,742...84,405,300 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 affects binding ISO Aripiprazole binds to SLC6A4 protein CTD PMID:21823597 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression EXP Aripiprazole results in decreased expression of SLCO2B1 mRNA CTD PMID:17868501 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Slit3 slit guidance ligand 3 increases expression EXP Aripiprazole results in increased expression of SLIT3 mRNA CTD PMID:17868501 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SMAD3 mRNA CTD PMID:31476115 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of SOCS1 mRNA CTD PMID:31476115 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Syt17 synaptotagmin 17 decreases expression
multiple interactions		 ISO Aripiprazole results in decreased expression of SYT17 mRNA
[Aripiprazole co-treated with Ozone] results in decreased expression of SYT17 mRNA		 CTD PMID:31476115 NCBI chr 1:172,695,275...172,761,906
Ensembl chr 1:172,696,120...172,761,960 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TAB1 mRNA CTD PMID:31476115 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
G Tacr3 tachykinin receptor 3 decreases expression
increases expression		 EXP Aripiprazole results in decreased expression of TACR3 mRNA
Aripiprazole results in increased expression of TACR3 mRNA		 CTD PMID:17868501 NCBI chr 2:223,266,536...223,363,791
Ensembl chr 2:223,266,536...223,363,791 		JBrowse link
G Thbd thrombomodulin multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of THBD mRNA CTD PMID:31476115 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of THBS1 mRNA] CTD PMID:31476115 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TICAM1 mRNA CTD PMID:31476115 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tlr3 toll-like receptor 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TLR3 mRNA CTD PMID:31476115 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlr5 toll-like receptor 5 increases expression
multiple interactions		 ISO Aripiprazole results in increased expression of TLR5 mRNA
[Aripiprazole co-treated with Ozone] results in decreased expression of TLR5 mRNA		 CTD PMID:31476115 NCBI chr13:94,634,778...94,658,992
Ensembl chr13:94,634,801...94,657,738 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of TNF mRNA] CTD PMID:31476115 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFAIP3 mRNA CTD PMID:31476115 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfrsf11b TNF receptor superfamily member 11B multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in increased expression of TNFRSF11B mRNA] CTD PMID:31476115 NCBI chr 7:85,566,520...85,594,526
Ensembl chr 7:85,566,520...85,594,538 		JBrowse link
G Tnfrsf12a TNF receptor superfamily member 12A multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF12A mRNA CTD PMID:31476115 NCBI chr10:12,707,077...12,709,071
Ensembl chr10:12,689,890...12,709,045 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TNFRSF14 mRNA CTD PMID:31476115 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF1B mRNA CTD PMID:31476115 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 multiple interactions ISO Aripiprazole inhibits the reaction [Ozone results in decreased expression of TNFRSF10C mRNA] CTD PMID:31476115 NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309 		JBrowse link
G Tnfrsf8 TNF receptor superfamily member 8 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF8 mRNA CTD PMID:31476115 NCBI chr 5:157,123,183...157,168,421
Ensembl chr 5:157,123,185...157,168,421 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFRSF9 mRNA CTD PMID:31476115 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TNFSF10 mRNA CTD PMID:31476115 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnfsf12 TNF superfamily member 12 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in decreased expression of TNFSF12 mRNA CTD PMID:31476115 NCBI chr10:54,403,870...54,413,213
Ensembl chr10:54,403,870...54,413,213 		JBrowse link
G Tnfsf15 TNF superfamily member 15 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFSF15 mRNA CTD PMID:31476115 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Tnfsf18 TNF superfamily member 18 multiple interactions ISO [Aripiprazole co-treated with Ozone] results in increased expression of TNFSF18 mRNA CTD PMID:31476115 NCBI chr13:73,833,478...73,907,249
Ensembl chr13:73,831,252...73,843,169 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP Aripiprazole results in decreased expression of TUBB2A mRNA CTD PMID:17868501 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO Aripiprazole promotes the reaction [Ozone results in increased expression of VEGFA mRNA] CTD PMID:31476115 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Wee1 WEE1 G2 checkpoint kinase increases expression EXP Aripiprazole results in increased expression of WEE1 mRNA CTD PMID:17868501 NCBI chr 1:164,173,681...164,197,688
Ensembl chr 1:164,174,779...164,197,688 		JBrowse link
G Zfp354c zinc finger protein 354C increases expression EXP Aripiprazole results in increased expression of ZNF354C mRNA CTD PMID:17868501 NCBI chr10:35,129,720...35,145,717
Ensembl chr10:35,132,959...35,145,661 		JBrowse link
asenapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
decreases expression		 ISO Asenapine results in decreased activity of CYP1A2 protein
Asenapine results in decreased expression of CYP1A2 mRNA		 CTD PMID:32941854 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
azaperone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Azaperone results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
cariprazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhcr7 7-dehydrocholesterol reductase decreases activity ISO cariprazine results in decreased activity of DHCR7 protein CTD PMID:29698737 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
chlorpromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases expression		 ISO
EXP		 [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCB11 mRNA
Chlorpromazine results in decreased expression of ABCB11 mRNA; Chlorpromazine results in decreased expression of ABCB11 protein		 CTD PMID:27344345 PMID:27765674 PMID:28391356 PMID:35708773 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression
decreases activity		 ISO Chlorpromazine analog results in increased expression of ABCB1 mRNA
Chlorpromazine results in decreased activity of ABCB1 protein		 CTD PMID:15924885 PMID:16810505 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects activity EXP Chlorpromazine affects the activity of ABCB1B protein CTD PMID:12626638 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCB4 mRNA CTD PMID:27344345 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcb6 ATP binding cassette subfamily B member 6 decreases expression EXP Chlorpromazine results in decreased expression of ABCB6 mRNA CTD PMID:25596134 NCBI chr 9:76,668,554...76,677,263
Ensembl chr 9:76,668,554...76,676,924 		JBrowse link
G Abcb9 ATP binding cassette subfamily B member 9 increases expression EXP Chlorpromazine results in increased expression of ABCB9 mRNA CTD PMID:25596134 NCBI chr12:32,499,213...32,531,932
Ensembl chr12:32,499,225...32,531,931 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
multiple interactions		 EXP
ISO		 Chlorpromazine results in increased expression of ABCC2 mRNA
[Bile Acids and Salts co-treated with Chlorpromazine] results in decreased expression of ABCC2 mRNA		 CTD PMID:27765674 PMID:35708773 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc3 ATP binding cassette subfamily C member 3 increases expression
multiple interactions
decreases expression		 ISO
EXP		 Chlorpromazine analog results in increased expression of ABCC3 mRNA
[Bile Acids and Salts co-treated with Chlorpromazine] results in decreased expression of ABCC3 mRNA
Chlorpromazine results in decreased expression of ABCC3 mRNA		 CTD PMID:15924885 PMID:25596134 PMID:35708773 NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595 		JBrowse link
G Abcc4 ATP binding cassette subfamily C member 4 increases expression ISO Chlorpromazine results in increased expression of ABCC4 mRNA CTD PMID:35708773 NCBI chr15:95,541,186...95,774,898
Ensembl chr15:95,542,315...95,774,283 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Chlorpromazine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ABCG8 mRNA CTD PMID:27344345 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases phosphorylation EXP Chlorpromazine results in decreased phosphorylation of ACACA protein CTD PMID:17512020 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Ace2 angiotensin converting enzyme 2 decreases expression ISO Chlorpromazine results in decreased expression of ACE2 mRNA CTD PMID:32808185 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Ache acetylcholinesterase decreases activity
increases activity
multiple interactions		 ISO Chlorpromazine results in decreased activity of ACHE protein
Chlorpromazine results in increased activity of ACHE protein
Dichlorvos promotes the reaction [Chlorpromazine results in decreased activity of ACHE protein]		 CTD PMID:4859365 PMID:29614332 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA] CTD PMID:21869564 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Adra1a adrenoceptor alpha 1A decreases activity EXP Chlorpromazine results in decreased activity of ADRA1A protein CTD PMID:23611293 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Adra1b adrenoceptor alpha 1B decreases activity EXP Chlorpromazine results in decreased activity of ADRA1B protein CTD PMID:23611293 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Afp alpha-fetoprotein decreases expression ISO Chlorpromazine analog results in decreased expression of AFP mRNA CTD PMID:15924885 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Agrn agrin decreases expression EXP Chlorpromazine results in decreased expression of AGRN mRNA CTD PMID:25596134 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003 		JBrowse link
G Ahr aryl hydrocarbon receptor affects activity EXP Chlorpromazine affects the activity of AHR protein CTD PMID:25596134 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ak3 adenylate kinase 3 decreases expression EXP Chlorpromazine results in decreased expression of AK3 mRNA CTD PMID:25596134 NCBI chr 1:226,737,472...226,764,647
Ensembl chr 1:226,739,318...226,764,625 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation EXP Chlorpromazine results in decreased phosphorylation of AKT1 protein CTD PMID:17512020 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of ALDH1A1 mRNA CTD PMID:27344345 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Chlorpromazine results in increased expression of ALDOA mRNA CTD PMID:25596134 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions ISO Chlorpromazine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]; Chlorpromazine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606 		JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO Chlorpromazine results in decreased expression of AP1S1 mRNA CTD PMID:17175557 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713 		JBrowse link
G Apoc4 apolipoprotein C4 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of APOC4 mRNA CTD PMID:27344345 NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981 		JBrowse link
G Apof apolipoprotein F multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of APOF mRNA CTD PMID:27344345 NCBI chr 7:700,688...702,130
Ensembl chr 7:700,762...701,946 		JBrowse link
G Areg amphiregulin decreases expression ISO Chlorpromazine results in decreased expression of AREG mRNA CTD PMID:15924885 PMID:30703373 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arfgef2 ADP ribosylation factor guanine nucleotide exchange factor 2 increases expression EXP Chlorpromazine results in increased expression of ARFGEF2 mRNA CTD PMID:25596134 NCBI chr 3:155,547,504...155,633,652
Ensembl chr 3:155,547,538...155,630,856 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 decreases expression EXP Chlorpromazine results in decreased expression of ARHGEF10 mRNA CTD PMID:25596134 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO Chlorpromazine results in increased expression of ASAH1 mRNA CTD PMID:17175557 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Chlorpromazine results in increased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Atf4 activating transcription factor 4 affects activity
multiple interactions		 EXP
ISO		 Chlorpromazine affects the activity of ATF4 protein
[Chlorpromazine co-treated with Cholic Acids] affects the expression of ATF4 mRNA		 CTD PMID:25596134 PMID:27344345 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression EXP Chlorpromazine results in decreased expression of ATP6V1B2 protein CTD PMID:19441803 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Avp arginine vasopressin increases expression
multiple interactions		 ISO
EXP		 Chlorpromazine results in increased expression of AVP protein
Chlorpromazine inhibits the reaction [Lithium results in increased expression of AVP protein]		 CTD PMID:3567260 PMID:3976404 NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425 		JBrowse link
G Bag4 BAG cochaperone 4 decreases expression ISO Chlorpromazine analog results in decreased expression of BAG4 mRNA CTD PMID:15924885 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Chlorpromazine results in increased expression of BCL2L1 mRNA CTD PMID:21683644 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor affects response to substance
affects expression		 ISO
EXP		 BDNF affects the susceptibility to Chlorpromazine
Chlorpromazine affects the expression of BDNF mRNA		 CTD PMID:18408624 PMID:31324950 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression ISO Chlorpromazine analog results in increased expression of BHLHE40 mRNA CTD PMID:15924885 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases expression ISO Chlorpromazine results in decreased expression of BIRC2 mRNA CTD PMID:30703373 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO Chlorpromazine analog results in decreased expression of BIRC5 mRNA; Chlorpromazine results in decreased expression of BIRC5 mRNA CTD PMID:15924885 PMID:30703373 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression EXP Chlorpromazine results in increased expression of BNIP3 mRNA CTD PMID:25596134 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression ISO Chlorpromazine analog results in increased expression of BTG2 mRNA CTD PMID:15924885 NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628 		JBrowse link
G Btg3 BTG anti-proliferation factor 3 increases expression ISO Chlorpromazine analog results in increased expression of BTG3 mRNA CTD PMID:15924885 NCBI chr11:17,030,156...17,046,069
Ensembl chr11:17,030,160...17,046,170 		JBrowse link
G C3 complement C3 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of C3 mRNA CTD PMID:27344345 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C6 complement C6 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of C6 mRNA CTD PMID:27344345 NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275 		JBrowse link
G Calcr calcitonin receptor multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA] CTD PMID:21869564 NCBI chr 4:31,661,270...31,736,392
Ensembl chr 4:31,661,273...31,736,392 		JBrowse link
G Calr calreticulin decreases expression EXP Chlorpromazine results in decreased expression of CALR mRNA CTD PMID:18246545 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA] CTD PMID:21869564 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Cat catalase multiple interactions
decreases expression
decreases activity		 EXP
ISO		 carvedilol inhibits the reaction [Chlorpromazine results in decreased expression of CAT protein]; zolpidem inhibits the reaction [Chlorpromazine results in decreased activity of CAT] CTD PMID:12010767 PMID:17513028 PMID:25449126 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO Chlorpromazine results in decreased expression of CCN2 mRNA; Chlorpromazine results in decreased expression of CCN2 protein CTD PMID:30703373 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccn3 cellular communication network factor 3 affects expression EXP Chlorpromazine affects the expression of CCN3 mRNA CTD PMID:31324950 NCBI chr 7:86,094,000...86,101,022
Ensembl chr 7:86,094,000...86,101,019 		JBrowse link
G Ccnb2 cyclin B2 decreases expression ISO Chlorpromazine analog results in decreased expression of CCNB2 mRNA; Chlorpromazine results in decreased expression of CCNB2 mRNA CTD PMID:15924885 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Chlorpromazine results in decreased expression of CCND1 mRNA CTD PMID:17202759 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 decreases expression ISO Chlorpromazine analog results in decreased expression of CCND3 mRNA CTD PMID:15924885 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccnf cyclin F decreases expression ISO Chlorpromazine analog results in decreased expression of CCNF mRNA CTD PMID:15924885 NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101 		JBrowse link
G Cd274 CD274 molecule multiple interactions ISO Chlorpromazine inhibits the reaction [platycodin D results in decreased expression of and results in increased secretion of CD274 protein] CTD PMID:31150782 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Cd44 CD44 molecule multiple interactions
decreases expression		 ISO Chlorpromazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein]
Chlorpromazine results in decreased expression of CD44 protein		 CTD PMID:9929743 PMID:30703373 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd86 CD86 molecule increases expression ISO Chlorpromazine results in increased expression of CD86 protein CTD PMID:19665512 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO Chlorpromazine analog results in decreased expression of CDK5 mRNA CTD PMID:15924885 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdk7 cyclin-dependent kinase 7 increases expression ISO Chlorpromazine analog results in increased expression of CDK7 mRNA CTD PMID:15924885 NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 EXP [EGR1 binds to CDKN1A promoter] promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; EGR1 promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA] CTD PMID:20368687 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO Chlorpromazine analog results in decreased expression of CDKN2C mRNA CTD PMID:15924885 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Ces2h carboxylesterase 2H multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CES2 mRNA CTD PMID:27344345 NCBI chr19:32,974,242...32,988,842
Ensembl chr19:32,974,242...32,988,830 		JBrowse link
G Cfh complement factor H multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CFH mRNA CTD PMID:27344345 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cgref1 cell growth regulator with EF hand domain 1 decreases expression EXP Chlorpromazine results in decreased expression of CGREF1 mRNA CTD PMID:17202759 NCBI chr 6:25,431,846...25,443,853
Ensembl chr 6:25,431,799...25,443,852 		JBrowse link
G Chtf18 chromosome transmission fidelity factor 18 decreases expression ISO Chlorpromazine analog results in decreased expression of CHTF18 mRNA CTD PMID:15924885 NCBI chr10:14,743,006...14,751,044
Ensembl chr10:14,742,621...14,751,050 		JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 decreases expression EXP Chlorpromazine results in decreased expression of CITED2 mRNA CTD PMID:18246545 NCBI chr 1:12,312,426...12,314,869
Ensembl chr 1:12,312,160...12,314,897 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 decreases expression ISO Chlorpromazine analog results in decreased expression of CKS2 mRNA CTD PMID:15924885 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clcf1 cardiotrophin-like cytokine factor 1 increases expression ISO Chlorpromazine results in increased expression of CLCF1 mRNA CTD PMID:21683644 NCBI chr 1:201,507,763...201,517,607
Ensembl chr 1:201,507,859...201,517,605 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of COL18A1 mRNA CTD PMID:27344345 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Chlorpromazine results in increased expression of COL1A1 mRNA CTD PMID:35708773 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression EXP Chlorpromazine results in decreased expression of COL4A1 mRNA CTD PMID:25596134 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Cort cortistatin affects expression EXP Chlorpromazine affects the expression of CORT mRNA CTD PMID:31324950 NCBI chr 5:159,560,591...159,562,032 JBrowse link
G Cox8a cytochrome c oxidase subunit 8A affects expression
increases expression		 EXP Chlorpromazine affects the expression of COX8A mRNA
Chlorpromazine results in increased expression of COX8A mRNA		 CTD PMID:18246545 NCBI chr 1:204,402,118...204,404,439 JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Chlorpromazine results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cth cystathionine gamma-lyase decreases expression EXP Chlorpromazine results in decreased expression of CTH mRNA CTD PMID:25596134 NCBI chr 2:246,975,888...247,002,234
Ensembl chr 2:246,975,894...247,002,234 		JBrowse link
G Ctsk cathepsin K multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA] CTD PMID:21869564 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
decreases response to substance
increases expression		 ISO
EXP		 [Filipin co-treated with Chlorpromazine co-treated with Wortmannin] inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; Chlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Chlorpromazine results in decreased activity of CYP1A1 protein
CYP1A1 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in increased expression of CYP1A1 mRNA		 CTD PMID:17202759 PMID:18246545 PMID:18493746 PMID:25596134 PMID:26477383 More... NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions
decreases response to substance
increases expression
increases oxidation
affects expression
decreases methylation		 ISO
EXP		 [Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP1A2 mRNA; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine; Chlorpromazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; CYP1A2 protein results in increased metabolism of and results in increased activity of Chlorpromazine
CYP1A2 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in increased expression of CYP1A2 mRNA
CYP1A2 protein results in increased oxidation of Chlorpromazine
Chlorpromazine affects the expression of CYP1A2 mRNA
CYP1A2 protein results in decreased methylation of Chlorpromazine		 CTD PMID:18246545 PMID:18493746 PMID:19482014 PMID:20615392 PMID:23397584 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases response to substance
decreases activity
multiple interactions		 ISO CYP1B1 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in decreased activity of CYP1B1 protein
[Filipin co-treated with Chlorpromazine co-treated with Wortmannin] inhibits the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA]		 CTD PMID:26477383 PMID:29724254 PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions
decreases response to substance		 ISO [Chlorpromazine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; Chlorpromazine inhibits the reaction [Androstenols inhibits the reaction [NR1I3 protein results in increased expression of CYP2B6 mRNA]]
NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP2B10 mRNA]
CYP2B6 protein results in decreased susceptibility to Chlorpromazine		 CTD PMID:10037683 PMID:12049174 PMID:17041008 PMID:26477383 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases expression
decreases response to substance		 EXP
ISO		 Chlorpromazine results in decreased expression of CYP2C mRNA; Chlorpromazine results in decreased expression of CYP2C11 mRNA
CYP2C18 protein results in decreased susceptibility to Chlorpromazine		 CTD PMID:18246545 PMID:26477383 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
decreases response to substance
decreases activity
affects methylation		 ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine
CYP2C19 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in decreased activity of CYP2C19 protein
CYP2C19 protein affects the methylation of Chlorpromazine		 CTD PMID:15135088 PMID:20615392 PMID:23397584 PMID:26477383 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases response to substance ISO CYP2C8 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases response to substance		 ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine; CYP2D6 protein results in increased metabolism of and results in increased activity of Chlorpromazine
CYP2D6 protein results in decreased susceptibility to Chlorpromazine		 CTD PMID:19482014 PMID:23397584 PMID:26477383 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
decreases response to substance		 ISO Chlorpromazine results in decreased activity of CYP2E1 protein
CYP2E1 protein results in decreased susceptibility to Chlorpromazine		 CTD PMID:15135088 PMID:26477383 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 affects methylation
affects oxidation
multiple interactions
decreases response to substance
decreases activity		 ISO CYP3A4 protein affects the methylation of Chlorpromazine
CYP3A4 protein affects the oxidation of Chlorpromazine
[Chlorpromazine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Chlorpromazine
CYP3A4 protein results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in decreased activity of CYP3A4 protein		 CTD PMID:15135088 PMID:17041008 PMID:20615392 PMID:23397584 PMID:26477383 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 decreases response to substance ISO CYP3A5 protein results in decreased susceptibility to Chlorpromazine CTD PMID:26477383 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyp8b1 cytochrome P450 family 8 subfamily B member 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of CYP8B1 mRNA CTD PMID:27344345 NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166 		JBrowse link
G Dao D-amino-acid oxidase decreases activity ISO Chlorpromazine results in decreased activity of DAO protein CTD PMID:18615285 NCBI chr12:42,592,342...42,613,046
Ensembl chr12:42,592,343...42,612,741 		JBrowse link
G Dcstamp dendrocyte expressed seven transmembrane protein multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA] CTD PMID:21869564 NCBI chr 7:70,807,455...70,822,067
Ensembl chr 7:70,807,581...70,822,078 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression EXP Chlorpromazine results in increased expression of DDIT3 mRNA CTD PMID:25596134 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO Chlorpromazine results in increased expression of DEPP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Drd1 dopamine receptor D1 decreases activity ISO Chlorpromazine results in decreased activity of DRD1 protein CTD PMID:23611293 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 decreases response to substance
decreases activity		 ISO DRD2 polymorphism results in decreased susceptibility to Chlorpromazine
Chlorpromazine results in decreased activity of DRD2 protein		 CTD PMID:15694263 PMID:23611293 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression
affects expression		 ISO Chlorpromazine analog results in increased expression of DUSP1 mRNA
Chlorpromazine affects the expression of DUSP1 mRNA		 CTD PMID:15924885 PMID:20843724 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp9 dual specificity phosphatase 9 decreases expression ISO Chlorpromazine analog results in decreased expression of DUSP9 mRNA CTD PMID:15924885 NCBI chr  X:151,351,897...151,355,822
Ensembl chr  X:151,351,897...151,355,821 		JBrowse link
G E2f1 E2F transcription factor 1 decreases expression ISO Chlorpromazine analog results in decreased expression of E2F1 mRNA CTD PMID:15924885 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions		 EXP Chlorpromazine results in increased expression of EGR1
[EGR1 binds to CDKN1A promoter] promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; EGR1 promotes the reaction [Chlorpromazine results in increased expression of CDKN1A mRNA]; MAPK1 affects the reaction [Chlorpromazine results in increased expression of EGR1]; MAPK3 affects the reaction [Chlorpromazine results in increased expression of EGR1]		 CTD PMID:20368687 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Eif1 eukaryotic translation initiation factor 1 increases expression EXP Chlorpromazine results in increased expression of EIF1 mRNA CTD PMID:25596134 NCBI chr10:85,246,751...85,248,842
Ensembl chr10:85,246,764...85,427,327 		JBrowse link
G Eno2 enolase 2 increases expression EXP Chlorpromazine results in increased expression of ENO2 mRNA CTD PMID:25596134 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression EXP Chlorpromazine results in increased expression of ERO1A mRNA CTD PMID:25596134 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G F2 coagulation factor II, thrombin decreases expression ISO Chlorpromazine analog results in decreased expression of F2 mRNA CTD PMID:15924885 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Chlorpromazine results in increased expression of FABP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO Chlorpromazine analog results in increased expression of FAS mRNA CTD PMID:15924885 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fbp1 fructose-bisphosphatase 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FBP1 mRNA CTD PMID:27344345 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071 		JBrowse link
G Fbxo22 F-box protein 22 decreases expression EXP Chlorpromazine results in decreased expression of FBXO22 mRNA CTD PMID:25596134 NCBI chr 8:55,579,906...55,595,981
Ensembl chr 8:55,579,891...55,596,148 		JBrowse link
G Fech ferrochelatase decreases expression EXP Chlorpromazine results in decreased expression of FECH mRNA CTD PMID:25596134 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Fetub fetuin B multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FETUB mRNA CTD PMID:27344345 NCBI chr11:78,082,158...78,093,022
Ensembl chr11:78,082,156...78,095,135 		JBrowse link
G Fga fibrinogen alpha chain multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FGA mRNA CTD PMID:27344345 NCBI chr 2:168,374,120...168,381,523
Ensembl chr 2:168,374,120...168,381,528 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FGF2 mRNA CTD PMID:27344345 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 decreases expression ISO Chlorpromazine analog results in decreased expression of FGFR1 mRNA CTD PMID:15924885 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase decreases expression EXP Chlorpromazine results in decreased expression of FGR mRNA CTD PMID:25596134 NCBI chr 5:145,189,814...145,219,571
Ensembl chr 5:145,189,841...145,217,326 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO Chlorpromazine inhibits the reaction [Lipopolysaccharides results in decreased expression of FKBP5 protein] CTD PMID:21034739 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Chlorpromazine results in increased expression of FNDC4 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit affects expression ISO Chlorpromazine affects the expression of FOS mRNA CTD PMID:20843724 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit affects expression ISO Chlorpromazine affects the expression of FOSB mRNA CTD PMID:20843724 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression
affects expression		 ISO Chlorpromazine analog results in increased expression of FOSL1 mRNA
Chlorpromazine affects the expression of FOSL1 mRNA		 CTD PMID:15924885 PMID:20843724 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit affects expression ISO Chlorpromazine affects the expression of FOSL2 mRNA CTD PMID:20843724 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Fth1 ferritin heavy chain 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of FTH1 mRNA CTD PMID:27344345 NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression
decreases activity
multiple interactions		 ISO
EXP		 Chlorpromazine analog results in decreased expression of G6PD mRNA
Chlorpromazine results in decreased activity of G6PD protein
[Taurine co-treated with coenzyme Q10] inhibits the reaction [Chlorpromazine results in decreased activity of G6PD protein]; coenzyme Q10 inhibits the reaction [Chlorpromazine results in decreased activity of G6PD protein]; Taurine inhibits the reaction [Chlorpromazine results in decreased activity of G6PD protein]		 CTD PMID:15924885 PMID:33548410 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gad1 glutamate decarboxylase 1 decreases methylation
multiple interactions		 ISO Chlorpromazine results in decreased methylation of GAD1 promoter
Valproic Acid promotes the reaction [Chlorpromazine results in decreased methylation of GAD1 promoter]		 CTD PMID:19110320 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gcgr glucagon receptor multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of GCGR mRNA CTD PMID:27344345 NCBI chr10:105,808,474...105,816,641
Ensembl chr10:105,808,473...105,816,640 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit decreases expression EXP Chlorpromazine results in decreased expression of GCLC mRNA CTD PMID:25596134 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP Chlorpromazine results in increased expression of GDF15 mRNA CTD PMID:25596134 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Chlorpromazine results in increased expression of GDPD3 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Gfap glial fibrillary acidic protein affects expression EXP Chlorpromazine affects the expression of GFAP mRNA CTD PMID:31324950 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gpnmb glycoprotein nmb increases expression EXP Chlorpromazine results in increased expression of GPNMB mRNA CTD PMID:25596134 NCBI chr 4:78,010,247...78,031,491
Ensembl chr 4:78,010,197...78,049,367 		JBrowse link
G Gpt glutamic--pyruvic transaminase increases expression EXP Chlorpromazine results in increased expression of GPT protein CTD PMID:35722787 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity EXP Chlorpromazine results in decreased activity of GSR protein CTD PMID:6693892 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of GSTA1 mRNA CTD PMID:27344345 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha affects activity EXP Chlorpromazine affects the activity of HIF1A protein CTD PMID:25596134 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Chlorpromazine results in increased expression of HMGCR mRNA CTD PMID:17052361 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Chlorpromazine results in increased expression of HMGCS1 mRNA CTD PMID:17052361 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
affects expression		 ISO
EXP		 Chlorpromazine results in increased expression of HMOX1 mRNA
Chlorpromazine affects the expression of HMOX1 mRNA		 CTD PMID:15924885 PMID:25596134 PMID:31324950 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hpn hepsin increases expression ISO Chlorpromazine results in increased expression of HPN mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 increases expression
decreases expression		 EXP Chlorpromazine results in increased expression of HSPA2 mRNA
Chlorpromazine results in decreased expression of HSPA2 mRNA; Chlorpromazine results in decreased expression of HSPA2 protein		 CTD PMID:36751017 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression
decreases expression		 EXP Chlorpromazine results in increased expression of HSPB1 mRNA
Chlorpromazine results in decreased expression of HSPB1 mRNA		 CTD PMID:36751017 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 increases expression EXP Chlorpromazine results in increased expression of HSPD1 mRNA CTD PMID:36751017 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP Chlorpromazine results in increased expression of HSPE1 mRNA CTD PMID:36751017 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Ibsp integrin-binding sialoprotein decreases expression
multiple interactions		 EXP Chlorpromazine results in decreased expression of IBSP mRNA
herbimycin inhibits the reaction [Chlorpromazine results in decreased expression of IBSP mRNA]; U 0126 inhibits the reaction [Chlorpromazine results in decreased expression of IBSP mRNA]		 CTD PMID:16294319 NCBI chr14:5,439,825...5,452,570
Ensembl chr14:5,439,829...5,452,693 		JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Chlorpromazine promotes the reaction [PAM2-CSK4 results in increased expression of IFNB1 mRNA] CTD PMID:32796029 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA CTD PMID:29594315 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifnlr1 interferon, lambda receptor 1 increases expression ISO Chlorpromazine results in increased expression of IFNLR1 mRNA CTD PMID:21683644 NCBI chr 5:147,919,547...147,942,328
Ensembl chr 5:147,919,908...147,942,332 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Chlorpromazine results in increased expression of IGFBP1 mRNA CTD PMID:15924885 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma increases expression ISO Chlorpromazine analog results in increased expression of IKBKG mRNA CTD PMID:15924885 NCBI chr  X:152,216,485...152,241,476
Ensembl chr  X:152,216,596...152,239,499 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine CTD PMID:19362101 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta decreases expression ISO Chlorpromazine results in decreased expression of IL1B mRNA CTD PMID:29594315 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Chlorpromazine co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA; Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]; Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein] CTD PMID:11014349 PMID:29594315 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine CTD PMID:19362101 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Chlorpromazine results in increased expression of INHBE mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Ins1 insulin 1 decreases secretion EXP Chlorpromazine results in decreased secretion of INS1 protein CTD PMID:18308779 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Insig2 insulin induced gene 2 decreases expression EXP Chlorpromazine results in decreased expression of INSIG2 mRNA CTD PMID:25596134 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions EXP Chlorpromazine results in decreased expression of and results in decreased phosphorylation of IRS2 protein; Chlorpromazine results in decreased expression of and results in increased degradation of IRS2 protein CTD PMID:17512020 PMID:18308779 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Chlorpromazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Chlorpromazine results in decreased activity of KCNH2 protein		 CTD PMID:15071359 PMID:21158687 PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases activity EXP Chlorpromazine results in decreased activity of KCNN2 protein CTD PMID:10915830 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Klf4 KLF transcription factor 4 multiple interactions
decreases expression		 ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KLF4 mRNA
Chlorpromazine results in decreased expression of KLF4 mRNA		 CTD PMID:27344345 PMID:30703373 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Klkb1 kallikrein B1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KLKB1 mRNA CTD PMID:27344345 NCBI chr16:46,958,634...46,982,054
Ensembl chr16:46,958,707...46,982,053 		JBrowse link
G Kng1 kininogen 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of KNG1 mRNA CTD PMID:27344345 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Lats1 large tumor suppressor kinase 1 increases phosphorylation ISO Chlorpromazine results in increased phosphorylation of LATS1 protein CTD PMID:30703373 NCBI chr 1:2,160,411...2,193,640
Ensembl chr 1:2,160,411...2,193,640 		JBrowse link
G Ldhc lactate dehydrogenase C decreases activity
multiple interactions		 EXP Chlorpromazine results in decreased activity of LDHC protein
[Taurine co-treated with coenzyme Q10] inhibits the reaction [Chlorpromazine results in decreased activity of LDHC protein]; coenzyme Q10 inhibits the reaction [Chlorpromazine results in decreased activity of LDHC protein]; Taurine inhibits the reaction [Chlorpromazine results in decreased activity of LDHC protein]		 CTD PMID:33548410 NCBI chr 1:97,385,984...97,403,382
Ensembl chr 1:97,382,379...97,403,378 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Chlorpromazine results in increased expression of LDLR mRNA CTD PMID:17052361 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lep leptin increases expression EXP Chlorpromazine results in increased expression of LEP protein CTD PMID:17512020 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lss lanosterol synthase increases expression ISO Chlorpromazine results in increased expression of LSS mRNA CTD PMID:15342952 PMID:17175557 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP Chlorpromazine results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO
EXP		 Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]
MAPK1 affects the reaction [Chlorpromazine results in increased expression of EGR1]		 CTD PMID:11014349 PMID:20368687 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 decreases expression ISO Chlorpromazine analog results in decreased expression of MAPK14 mRNA CTD PMID:15924885 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases expression
multiple interactions		 ISO
EXP		 Chlorpromazine analog results in decreased expression of MAPK3 mRNA
MAPK3 affects the reaction [Chlorpromazine results in increased expression of EGR1]
Chlorpromazine inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]		 CTD PMID:11014349 PMID:15924885 PMID:20368687 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO [Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein; Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]] CTD PMID:23238562 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapkapk2 MAPK activated protein kinase 2 increases expression EXP Chlorpromazine results in increased expression of MAPKAPK2 mRNA CTD PMID:19441803 NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457 		JBrowse link
G Mcm3 minichromosome maintenance complex component 3 decreases expression ISO Chlorpromazine analog results in decreased expression of MCM3 mRNA CTD PMID:15924885 NCBI chr 9:23,219,169...23,237,314
Ensembl chr 9:23,219,169...23,237,314 		JBrowse link
G Mcm5 minichromosome maintenance complex component 5 decreases expression ISO Chlorpromazine analog results in decreased expression of MCM5 mRNA CTD PMID:15924885 NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389 		JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP Chlorpromazine results in increased expression of MDM2 mRNA CTD PMID:25596134 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mitf melanocyte inducing transcription factor increases expression ISO Chlorpromazine results in increased expression of MITF protein CTD PMID:25449126 NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145 		JBrowse link
G Mki67 marker of proliferation Ki-67 decreases expression ISO Chlorpromazine analog results in decreased expression of MKI67 mRNA CTD PMID:15924885 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions ISO Chlorpromazine inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased expression of MMP9 mRNA]; Chlorpromazine inhibits the reaction [FSL-1 lipoprotein, synthetic results in increased secretion of MMP9 protein] CTD PMID:25200491 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Msc musculin decreases expression EXP Chlorpromazine results in decreased expression of MSC mRNA CTD PMID:25596134 NCBI chr 5:4,547,335...4,553,206
Ensembl chr 5:4,547,405...4,553,203 		JBrowse link
G Msh2 mutS homolog 2 decreases expression ISO Chlorpromazine results in decreased expression of MSH2 mRNA CTD PMID:15924885 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938 		JBrowse link
G Mst1 macrophage stimulating 1 increases phosphorylation ISO Chlorpromazine results in increased phosphorylation of MST1 protein CTD PMID:30703373 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416 		JBrowse link
G Mt1 metallothionein 1 increases expression EXP Chlorpromazine results in increased expression of MT1A mRNA CTD PMID:8128501 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mybl2 MYB proto-oncogene like 2 decreases expression ISO Chlorpromazine analog results in decreased expression of MYBL2 mRNA CTD PMID:15924885 NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO Chlorpromazine results in decreased expression of MYC mRNA CTD PMID:30703373 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nampt nicotinamide phosphoribosyltransferase increases expression EXP Chlorpromazine results in increased expression of NAMPT mRNA CTD PMID:25596134 NCBI chr 6:49,425,316...49,462,109
Ensembl chr 6:49,424,332...49,462,100 		JBrowse link
G Nanog Nanog homeobox decreases expression ISO Chlorpromazine results in decreased expression of NANOG mRNA CTD PMID:30703373 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Ndufs3 NADH:ubiquinone oxidoreductase core subunit S3 decreases expression EXP Chlorpromazine results in decreased expression of NDUFS3 protein CTD PMID:19441803 NCBI chr 3:76,876,646...76,883,824
Ensembl chr 3:76,876,646...76,883,824 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 multiple interactions ISO Chlorpromazine inhibits the reaction [Cadmium Chloride results in decreased expression of and affects the localization of NECTIN2 protein] CTD PMID:25046863 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression EXP Chlorpromazine results in decreased expression of NEDD9 mRNA CTD PMID:25596134 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Nefh neurofilament heavy chain affects expression EXP Chlorpromazine affects the expression of NEFH mRNA CTD PMID:31324950 NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 multiple interactions ISO Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA] CTD PMID:21869564 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression
affects activity		 EXP Chlorpromazine results in decreased expression of NFE2L2 mRNA
Chlorpromazine affects the activity of NFE2L2 protein		 CTD PMID:25596134 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ninj1 ninjurin 1 increases expression EXP Chlorpromazine results in increased expression of NINJ1 mRNA CTD PMID:25596134 NCBI chr17:15,452,804...15,461,684
Ensembl chr17:15,452,813...15,461,704 		JBrowse link
G Nppb natriuretic peptide B increases expression EXP Chlorpromazine results in increased expression of NPPB protein CTD PMID:36751017 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Chlorpromazine results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 decreases expression EXP Chlorpromazine results in decreased expression of NR1H4 mRNA CTD PMID:27765674 PMID:28391356 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases expression
multiple interactions		 ISO Chlorpromazine analog results in increased expression of NR1I2 mRNA
[Chlorpromazine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA		 CTD PMID:15924885 PMID:17041008 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity
increases expression
multiple interactions		 ISO Chlorpromazine results in increased activity of NR1I3 protein
Chlorpromazine results in increased expression of NR1I3 mRNA
[Chlorpromazine co-treated with Cholic Acids] affects the expression of NR1I3 mRNA; [Chlorpromazine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA; Chlorpromazine inhibits the reaction [Androstenols inhibits the reaction [NR1I3 protein results in increased expression of CYP2B6 mRNA]]
NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP2B10 mRNA]; NR1I3 protein affects the reaction [Chlorpromazine results in increased expression of CYP3A11 mRNA]		 CTD PMID:10037683 PMID:12049174 PMID:12948398 PMID:17041008 PMID:22310298 More... NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Chlorpromazine inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein] CTD PMID:16581232 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Chlorpromazine results in increased expression of NUPR1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Orc1 origin recognition complex, subunit 1 decreases expression ISO Chlorpromazine analog results in decreased expression of ORC1 mRNA CTD PMID:15924885 NCBI chr 5:123,324,273...123,348,375
Ensembl chr 5:123,324,315...123,348,375 		JBrowse link
G Orm1 orosomucoid 1 affects binding
multiple interactions		 ISO Chlorpromazine binds to ORM1 protein alternative form
Chlorpromazine inhibits the reaction [Warfarin binds to ORM1 protein alternative form]		 CTD PMID:8946472 NCBI chr 5:76,766,637...76,776,149
Ensembl chr 5:76,772,941...76,776,154 		JBrowse link
G Pdia2 protein disulfide isomerase family A, member 2 increases expression ISO Chlorpromazine analog results in increased expression of PDIA2 mRNA CTD PMID:15924885 NCBI chr10:15,215,824...15,218,937
Ensembl chr10:15,215,824...15,220,931 		JBrowse link
G Pdia5 protein disulfide isomerase family A, member 5 decreases expression EXP Chlorpromazine results in decreased expression of PDIA5 mRNA CTD PMID:25596134 NCBI chr11:65,272,152...65,359,087
Ensembl chr11:65,272,155...65,359,084 		JBrowse link
G Pdk1 pyruvate dehydrogenase kinase 1 increases expression EXP Chlorpromazine results in increased expression of PDK1 mRNA CTD PMID:25596134 NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038 		JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression EXP Chlorpromazine results in increased expression of PDK4 mRNA CTD PMID:25596134 NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850 		JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase increases expression ISO Chlorpromazine results in increased expression of PHYH mRNA CTD PMID:15342952 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409 		JBrowse link
G Pias1 protein inhibitor of activated STAT, 1 increases expression ISO Chlorpromazine results in increased expression of PIAS1 mRNA CTD PMID:21683644 NCBI chr 8:63,338,150...63,451,670
Ensembl chr 8:63,338,150...63,438,905 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression ISO Chlorpromazine analog results in increased expression of PIM1 mRNA CTD PMID:15924885 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Pir pirin decreases expression EXP Chlorpromazine results in decreased expression of PIR mRNA CTD PMID:25596134 NCBI chr  X:30,108,536...30,219,269
Ensembl chr  X:30,108,538...30,219,218 		JBrowse link
G Plin2 perilipin 2 increases expression EXP Chlorpromazine results in increased expression of PLIN2 mRNA CTD PMID:25596134 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Pmepa1 prostate transmembrane protein, androgen induced 1 decreases expression EXP Chlorpromazine results in decreased expression of PMEPA1 mRNA CTD PMID:25596134 NCBI chr 3:162,011,884...162,060,343
Ensembl chr 3:162,012,751...162,060,454 		JBrowse link
G Pola1 DNA polymerase alpha 1, catalytic subunit decreases expression ISO Chlorpromazine analog results in decreased expression of POLA1 mRNA CTD PMID:15924885 NCBI chr  X:58,034,617...58,348,612
Ensembl chr  X:58,034,619...58,348,536 		JBrowse link
G Pold4 DNA polymerase delta 4, accessory subunit increases expression ISO Chlorpromazine analog results in increased expression of POLD4 mRNA CTD PMID:15924885 NCBI chr 1:201,526,591...201,528,406
Ensembl chr 1:201,526,665...201,528,401 		JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Chlorpromazine results in decreased expression of POU5F1 mRNA CTD PMID:30703373 NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects activity EXP Chlorpromazine affects the activity of PPARG protein CTD PMID:25596134 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A increases expression EXP Chlorpromazine results in increased expression of PPP1R15A mRNA CTD PMID:25596134 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 decreases phosphorylation EXP Chlorpromazine results in decreased phosphorylation of PRKAA1 protein CTD PMID:17512020 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G Prl prolactin increases expression ISO Chlorpromazine results in increased expression of PRL protein CTD PMID:718334 PMID:996201 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Rara retinoic acid receptor, alpha decreases expression EXP Chlorpromazine results in decreased expression of RARA mRNA CTD PMID:18246545 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142 		JBrowse link
G Rnd1 Rho family GTPase 1 decreases expression EXP Chlorpromazine results in decreased expression of RND1 mRNA CTD PMID:25596134 NCBI chr 7:129,821,311...129,828,385
Ensembl chr 7:129,821,311...129,828,399 		JBrowse link
G Rnd3 Rho family GTPase 3 decreases expression EXP Chlorpromazine results in decreased expression of RND3 mRNA CTD PMID:25596134 NCBI chr 3:35,571,929...35,589,283
Ensembl chr 3:35,571,143...35,589,327 		JBrowse link
G Rnf121 ring finger protein 121 decreases expression EXP Chlorpromazine results in decreased expression of RNF121 mRNA CTD PMID:25596134 NCBI chr 1:156,377,368...156,439,936
Ensembl chr 1:156,377,364...156,446,826 		JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression EXP Chlorpromazine results in increased expression of RUNX1 mRNA CTD PMID:25596134 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Rxrg retinoid X receptor gamma affects response to substance ISO RXRG protein affects the susceptibility to Chlorpromazine CTD PMID:10336693 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 increases expression EXP Chlorpromazine results in increased expression of SAT1 mRNA CTD PMID:25596134 NCBI chr  X:40,158,354...40,161,641
Ensembl chr  X:40,157,046...40,196,813 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Chlorpromazine results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N increases expression ISO Chlorpromazine results in increased expression of SERPINA3 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpinh1 serpin family H member 1 increases expression ISO Chlorpromazine results in increased expression of SERPINH1 mRNA CTD PMID:35708773 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Sesn1 sestrin 1 decreases expression EXP Chlorpromazine results in decreased expression of SESN1 mRNA CTD PMID:25596134 NCBI chr20:45,294,876...45,387,698
Ensembl chr20:45,294,871...45,387,697 		JBrowse link
G Sik1 salt-inducible kinase 1 decreases expression EXP Chlorpromazine results in decreased expression of SIK1 mRNA CTD PMID:25596134 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression
increases expression		 EXP
ISO		 Chlorpromazine results in decreased expression of SLC10A1 mRNA
Chlorpromazine results in increased expression of SLC10A1 mRNA		 CTD PMID:27765674 PMID:28391356 PMID:35708773 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc12a8 solute carrier family 12, member 8 increases expression EXP Chlorpromazine results in increased expression of SLC12A8 mRNA CTD PMID:25596134 NCBI chr11:67,116,876...67,266,548
Ensembl chr11:67,116,877...67,266,834 		JBrowse link
G Slc19a1 solute carrier family 19 member 1 multiple interactions
decreases activity		 EXP Chlorpromazine inhibits the reaction [SLC19A1 protein results in increased uptake of Methotrexate]
Chlorpromazine results in decreased activity of SLC19A1 protein		 CTD PMID:17482559 NCBI chr20:11,584,410...11,602,429
Ensembl chr20:11,584,411...11,601,972 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression EXP Chlorpromazine results in increased expression of SLC1A5 mRNA CTD PMID:25596134 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Chlorpromazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a7 solute carrier family 22 member 7 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SLC22A7 mRNA CTD PMID:27344345 NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Chlorpromazine results in decreased expression of SLC2A3 mRNA CTD PMID:15342952 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc31a1 solute carrier family 31 member 1 multiple interactions ISO Chlorpromazine inhibits the reaction [Copper affects the localization of SLC31A1 protein] CTD PMID:12501239 NCBI chr 5:75,814,744...75,844,241
Ensembl chr 5:75,814,743...75,844,228 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression EXP Chlorpromazine results in increased expression of SLC3A2 mRNA CTD PMID:25596134 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc51b SLC51 subunit beta multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SLC51B mRNA CTD PMID:27344345 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145 		JBrowse link
G Slc6a6 solute carrier family 6 member 6 increases expression EXP Chlorpromazine results in increased expression of SLC6A6 mRNA CTD PMID:25596134 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 decreases expression EXP Chlorpromazine results in decreased expression of SLCO2B1 mRNA CTD PMID:25596134 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions EXP Chlorpromazine inhibits the reaction [Copper inhibits the reaction [Trientine results in decreased activity of SOD1 protein]] CTD PMID:22362149 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO Chlorpromazine results in decreased expression of SOX2 mRNA CTD PMID:30703373 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of SPP1 mRNA CTD PMID:27344345 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Spsb1 splA/ryanodine receptor domain and SOCS box containing 1 increases expression EXP Chlorpromazine results in increased expression of SPSB1 mRNA CTD PMID:25596134 NCBI chr 5:160,358,292...160,418,541
Ensembl chr 5:160,358,308...160,418,468 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase multiple interactions EXP Chlorpromazine inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased phosphorylation of SRC protein] CTD PMID:29702141 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Chlorpromazine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Strbp spermatid perinuclear RNA binding protein increases expression EXP Chlorpromazine results in increased expression of STRBP mRNA CTD PMID:25596134 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949 		JBrowse link
G Sts steroid sulfatase multiple interactions ISO Chlorpromazine inhibits the reaction [Tretinoin results in increased activity of STS protein] CTD PMID:16178010 NCBI chr  X:42,225,131...42,233,403
Ensembl chr  X:42,225,372...42,233,402 		JBrowse link
G Tagln transgelin decreases expression ISO Chlorpromazine results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tf transferrin affects localization ISO Chlorpromazine affects the localization of TF protein CTD PMID:12501239 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tfdp1 transcription factor Dp-1 decreases expression ISO Chlorpromazine analog results in decreased expression of TFDP1 mRNA CTD PMID:15924885 NCBI chr16:76,162,040...76,200,871
Ensembl chr16:76,162,043...76,200,817 		JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase increases expression EXP Chlorpromazine results in increased expression of TIPARP mRNA CTD PMID:25596134 NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327 		JBrowse link
G Tirap TIR domain containing adaptor protein multiple interactions ISO TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased phosphorylation of MAPK8 protein]; TIRAP gene mutant form inhibits the reaction [Chlorpromazine promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased phosphorylation of MAPK8 protein]]; TIRAP protein results in increased susceptibility to [Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4]; TIRAP protein results in increased susceptibility to [Chlorpromazine co-treated with lipoteichoic acid] CTD PMID:23238562 NCBI chr 8:33,531,724...33,548,508
Ensembl chr 8:33,531,725...33,547,432 		JBrowse link
G Tnf tumor necrosis factor decreases expression
increases response to substance
multiple interactions		 ISO Chlorpromazine analog results in decreased expression of TNF protein; Chlorpromazine results in decreased expression of TNF mRNA
TNF protein results in increased susceptibility to Chlorpromazine
[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein; [Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein; Chlorpromazine inhibits the reaction [[hydroquinone results in increased expression of TNF protein] which results in increased susceptibility to Methacholine Chloride]; Chlorpromazine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; pyrazolanthrone inhibits the reaction [TNF protein results in increased susceptibility to Chlorpromazine]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased expression of TNF protein]; TIRAP gene mutant form inhibits the reaction [[Chlorpromazine co-treated with lipoteichoic acid] results in increased expression of TNF protein]
[IL6 protein co-treated with IL1A protein co-treated with TNF protein co-treated with lipopolysaccharide, Escherichia coli O111 B4] results in increased susceptibility to Chlorpromazine; Chlorpromazine results in decreased expression of and results in decreased activity of TNF protein		 CTD PMID:8550079 PMID:15052360 PMID:19362101 PMID:20371967 PMID:22414385 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip8 TNF alpha induced protein 8 increases expression EXP Chlorpromazine results in increased expression of TNFAIP8 mRNA CTD PMID:25596134 NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517 		JBrowse link
G Tnfrsf14 TNF receptor superfamily member 14 increases expression ISO Chlorpromazine analog results in increased expression of TNFRSF14 mRNA CTD PMID:15924885 NCBI chr 5:165,486,069...165,494,421
Ensembl chr 5:165,484,262...165,493,703 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases activity
multiple interactions		 ISO Chlorpromazine results in decreased activity of TNFSF11; Chlorpromazine results in decreased activity of TNFSF11 protein
Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of ACP5 mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CALCR mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CAR2 mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of CTSK mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of DCSTAMP mRNA]; Chlorpromazine inhibits the reaction [TNFSF11 protein results in increased expression of NFATC1 mRNA]		 CTD PMID:21869564 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tp53 tumor protein p53 affects activity EXP Chlorpromazine affects the activity of TP53 protein CTD PMID:25596134 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trafd1 TRAF type zinc finger domain containing 1 decreases expression EXP Chlorpromazine results in decreased expression of TRAFD1 mRNA CTD PMID:25596134 NCBI chr12:35,165,606...35,179,525
Ensembl chr12:35,165,606...35,179,525 		JBrowse link
G Tuba1a tubulin, alpha 1A decreases expression ISO Chlorpromazine results in decreased expression of TUBA1A mRNA CTD PMID:27015953 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Txn1 thioredoxin 1 decreases expression EXP Chlorpromazine results in decreased expression of TXN1 mRNA CTD PMID:25596134 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO [Chlorpromazine co-treated with Cholic Acids] affects the expression of TXNRD1 mRNA CTD PMID:27344345 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Tyr tyrosinase increases expression ISO Chlorpromazine results in increased expression of TYR protein CTD PMID:25449126 NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207 		JBrowse link
G Ung uracil-DNA glycosylase decreases expression ISO Chlorpromazine analog results in decreased expression of UNG mRNA CTD PMID:15924885 NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206 		JBrowse link
G Unkl unk like zinc finger decreases expression EXP Chlorpromazine results in decreased expression of UNKL mRNA CTD PMID:25596134 NCBI chr10:14,206,125...14,252,226
Ensembl chr10:14,206,189...14,252,225 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Chlorpromazine analog results in increased expression of VEGFA mRNA CTD PMID:15924885 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfb vascular endothelial growth factor B increases expression EXP Chlorpromazine results in increased expression of VEGFB mRNA CTD PMID:25596134 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 increases expression EXP Chlorpromazine results in increased expression of WARS1 mRNA CTD PMID:25596134 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Chlorpromazine results in increased expression of WIPI1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846 		JBrowse link
G Xbp1 X-box binding protein 1 affects activity
decreases expression		 EXP Chlorpromazine affects the activity of XBP1 protein
Chlorpromazine results in decreased expression of XBP1 mRNA		 CTD PMID:25596134 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor decreases expression EXP Chlorpromazine results in decreased expression of XPC mRNA CTD PMID:25596134 NCBI chr 4:123,993,670...124,020,922
Ensembl chr 4:123,993,666...124,021,010 		JBrowse link
G Xrcc4 X-ray repair cross complementing 4 decreases expression ISO Chlorpromazine results in decreased expression of XRCC4 mRNA CTD PMID:15924885 NCBI chr 2:20,948,464...21,197,705
Ensembl chr 2:20,951,200...21,197,808 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator multiple interactions ISO Chlorpromazine results in decreased expression of and results in increased phosphorylation of and affects the localization of YAP1 protein CTD PMID:30703373 NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
clopenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Clopenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
clozapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aars1 alanyl-tRNA synthetase 1 increases expression ISO Clozapine results in increased expression of AARS1 protein CTD PMID:34122009 NCBI chr19:38,999,130...39,021,152
Ensembl chr19:38,999,163...39,021,147 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO Clozapine results in decreased activity of ABCB11 protein CTD PMID:22646477 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity		 EXP
ISO		 Clozapine inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]; Clozapine inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]; Clozapine inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein]
Clozapine results in decreased activity of ABCB1 protein		 CTD PMID:9111066 PMID:16810505 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B multiple interactions EXP Clozapine inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Clozapine inhibits the reaction [N-n-propylnorapomorphine results in increased activity of ABCB1B promoter]; Clozapine inhibits the reaction [Quinpirole results in increased activity of ABCB1B promoter] CTD PMID:9111066 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abce1 ATP binding cassette subfamily E member 1 increases expression ISO Clozapine results in increased expression of ABCE1 protein CTD PMID:34122009 NCBI chr19:28,205,566...28,230,489
Ensembl chr19:28,205,555...28,230,489 		JBrowse link
G Abcg1 ATP binding cassette subfamily G member 1 increases expression ISO Clozapine results in increased expression of ABCG1 mRNA CTD PMID:17346280 NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Clozapine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Ablim2 actin binding LIM protein family, member 2 increases expression ISO Clozapine results in increased expression of ABLIM2 mRNA CTD PMID:17346280 NCBI chr14:74,865,409...74,990,334
Ensembl chr14:74,866,281...74,990,334 		JBrowse link
G Acat2 acetyl-CoA acetyltransferase 2 increases expression ISO Clozapine results in increased expression of ACAT2 mRNA CTD PMID:17052361 NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression ISO Clozapine results in increased expression of ACOT2 protein CTD PMID:34122009 NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acot7 acyl-CoA thioesterase 7 decreases expression ISO Clozapine results in decreased expression of ACOT7 protein CTD PMID:34122009 NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP [Clozapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased activity of ACOX1 protein; [Clozapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased expression of ACOX1 mRNA CTD PMID:23226405 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Actb actin, beta decreases expression ISO Clozapine results in decreased expression of ACTB protein CTD PMID:34122009 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actbl2 actin, beta-like 2 increases expression ISO Clozapine results in increased expression of ACTBL2 protein CTD PMID:34122009 NCBI chr 2:42,858,020...42,860,767
Ensembl chr 2:42,858,020...42,860,767 		JBrowse link
G Actr3 actin related protein 3 decreases expression ISO Clozapine results in decreased expression of ACTR3 protein CTD PMID:34122009 NCBI chr13:36,800,739...36,843,837
Ensembl chr13:36,800,093...36,844,124 		JBrowse link
G Actr5 actin related protein 5 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of ACTR5 protein CTD PMID:34122009 NCBI chr 3:147,282,461...147,295,870
Ensembl chr 3:147,282,624...147,296,110 		JBrowse link
G Adam1a ADAM metallopeptidase domain 1a decreases expression EXP Clozapine results in decreased expression of ADAM1A mRNA CTD PMID:16715494 NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311 		JBrowse link
G Adamts12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of ADAMTS12 protein CTD PMID:34122009 NCBI chr 2:60,032,873...60,327,629
Ensembl chr 2:60,032,873...60,327,629 		JBrowse link
G Adcy5 adenylate cyclase 5 affects response to substance
multiple interactions		 ISO ADCY5 protein affects the susceptibility to Clozapine
SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Clozapine]		 CTD PMID:12223546 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of ADH5 protein CTD PMID:34122009 NCBI chr 2:226,975,184...226,987,591
Ensembl chr 2:226,947,466...226,987,591 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression
increases expression
multiple interactions		 ISO
EXP		 Clozapine results in decreased expression of ADIPOQ protein
Clozapine results in increased expression of ADIPOQ protein
Clozapine results in increased expression of ADIPOQ mRNA
Berberine inhibits the reaction [Clozapine results in increased expression of ADIPOQ mRNA]		 CTD PMID:17933447 PMID:18162013 PMID:20564506 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adora2a adenosine A2a receptor decreases expression ISO Clozapine results in decreased expression of ADORA2A mRNA CTD PMID:17266109 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions EXP Clozapine binds to and results in decreased activity of ADRA1A protein CTD PMID:16545797 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 decreases expression ISO Clozapine results in decreased expression of AGPAT1 mRNA CTD PMID:14647396 NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278 		JBrowse link
G Agt angiotensinogen multiple interactions ISO Clozapine inhibits the reaction [Dopamine promotes the reaction [AGT protein results in increased secretion of Aldosterone]]; Clozapine promotes the reaction [Raclopride promotes the reaction [Dopamine promotes the reaction [AGT protein results in increased secretion of Aldosterone]]] CTD PMID:11549694 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Aimp1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 increases expression ISO Clozapine results in increased expression of AIMP1 protein CTD PMID:34122009 NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728 		JBrowse link
G Ak1 adenylate kinase 1 decreases expression ISO Clozapine results in decreased expression of AK1 protein CTD PMID:34122009 NCBI chr 3:15,912,431...15,923,045
Ensembl chr 3:15,912,485...15,923,041 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
decreases expression
increases phosphorylation		 ISO
EXP		 Clozapine results in increased expression of AKT1 mRNA; Clozapine results in increased expression of AKT1 protein
Clozapine results in decreased expression of AKT1 mRNA
Clozapine results in increased phosphorylation of AKT1 protein		 CTD PMID:15860345 PMID:19440698 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression EXP Clozapine results in increased expression of AKT2 mRNA CTD PMID:15860345 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Alb albumin multiple interactions
affects binding		 EXP
ISO		 Clozapine results in decreased expression of and results in decreased reduction of ALB protein
Clozapine binds to ALB protein
[[[stearic acid binds to ALB protein] which affects the susceptibility to Clozapine] which affects the reduction of Cysteine] which affects the activity of ALB protein; [[stearic acid binds to ALB protein] which affects the susceptibility to Clozapine] which affects the reduction of Cysteine; [stearic acid binds to ALB protein] which affects the susceptibility to Clozapine; stearic acid inhibits the reaction [Clozapine binds to ALB protein]		 CTD PMID:31400341 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression ISO Clozapine results in increased expression of ALDH1A1 mRNA CTD PMID:17266109 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Clozapine results in increased expression of ALDOA mRNA CTD PMID:15860345 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Aldob aldolase, fructose-bisphosphate B increases expression
decreases expression		 ISO Clozapine results in increased expression of ALDOB protein
Clozapine results in decreased expression of ALDOB protein		 CTD PMID:34122009 PMID:36482696 NCBI chr 5:63,889,045...63,902,086
Ensembl chr 5:63,889,046...63,902,116 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression
increases expression		 ISO
EXP		 Clozapine results in decreased expression of ALDOC mRNA
Clozapine results in increased expression of ALDOC mRNA		 CTD PMID:15860345 PMID:16465460 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Alpp alkaline phosphatase, placental multiple interactions ISO Clozapine inhibits the reaction [Colforsin results in increased expression of ALPP mRNA]; Clozapine inhibits the reaction [Isoproterenol results in increased expression of ALPP mRNA] CTD PMID:16036225 NCBI chr 9:87,765,846...87,768,606
Ensembl chr 9:87,765,860...87,768,606 		JBrowse link
G Alyref Aly/REF export factor decreases expression ISO Clozapine results in decreased expression of ALYREF protein CTD PMID:34122009 NCBI chr10:105,871,424...105,875,076
Ensembl chr10:105,871,306...105,875,069 		JBrowse link
G Anxa1 annexin A1 decreases expression ISO Clozapine results in decreased expression of ANXA1 protein CTD PMID:34122009 NCBI chr 1:217,861,175...217,877,205
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Anxa5 annexin A5 decreases expression ISO Clozapine results in decreased expression of ANXA5 protein CTD PMID:34122009 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Anxa6 annexin A6 decreases expression ISO Clozapine results in decreased expression of ANXA6 protein CTD PMID:34122009 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO Clozapine results in decreased expression of AP1S1 mRNA CTD PMID:17175557 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 increases expression EXP Clozapine results in increased expression of AP2B1 mRNA CTD PMID:15860345 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013 		JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 increases expression ISO Clozapine results in increased expression of AP3B1 protein CTD PMID:34122009 NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935 		JBrowse link
G Apoa5 apolipoprotein A5 affects response to substance EXP APOA5 gene polymorphism affects the susceptibility to Clozapine CTD PMID:17726453 NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816 		JBrowse link
G Apod apolipoprotein D increases expression ISO Clozapine results in increased expression of APOD mRNA; Clozapine results in increased expression of APOD protein CTD PMID:11158250 PMID:14647396 PMID:17266109 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G App amyloid beta precursor protein increases expression ISO Clozapine results in increased expression of APP protein CTD PMID:36482696 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein decreases expression EXP Clozapine results in decreased expression of ARC mRNA CTD PMID:18208916 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Arhgef9 Cdc42 guanine nucleotide exchange factor 9 decreases expression ISO Clozapine results in decreased expression of ARHGEF9 mRNA CTD PMID:17266109 NCBI chr  X:59,919,560...60,077,538
Ensembl chr  X:59,920,870...60,077,513 		JBrowse link
G Arl8a ADP-ribosylation factor like GTPase 8A decreases expression ISO Clozapine results in decreased expression of ARL8A protein CTD PMID:34122009 NCBI chr13:46,585,845...46,594,851
Ensembl chr13:46,585,845...46,594,851 		JBrowse link
G Armt1 acidic residue methyltransferase 1 increases expression ISO Clozapine results in increased expression of ARMT1 protein CTD PMID:34122009 NCBI chr 1:40,894,558...40,918,302
Ensembl chr 1:40,894,550...40,918,302 		JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 affects expression ISO Clozapine affects the expression of ARPC4 mRNA CTD PMID:14647396 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO Clozapine results in increased expression of ASAH1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Clozapine results in increased expression of ASNS mRNA; Clozapine results in increased expression of ASNS protein CTD PMID:15342952 PMID:17175557 PMID:36482696 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Clozapine results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression ISO Clozapine results in increased expression of ASS1 protein CTD PMID:34122009 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Atad3a ATPase family, AAA domain containing 3A decreases expression ISO Clozapine results in decreased expression of ATAD3A protein CTD PMID:34122009 NCBI chr 5:166,350,302...166,370,492
Ensembl chr 5:166,350,304...166,370,482 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases expression ISO Clozapine results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression EXP Clozapine results in decreased expression of ATP5F1B protein CTD PMID:19441803 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Atp5pb ATP synthase peripheral stalk-membrane subunit b increases expression ISO Clozapine results in increased expression of ATP5F1 protein CTD PMID:34122009 NCBI chr 2:193,424,138...193,435,418
Ensembl chr 2:193,424,047...193,435,418 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A decreases expression ISO Clozapine results in decreased expression of ATP6V1A protein CTD PMID:34122009 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 decreases expression ISO Clozapine results in decreased expression of ATP6V1B1 protein CTD PMID:34122009 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression EXP
ISO		 Clozapine results in decreased expression of ATP6V1B2 protein CTD PMID:19441803 PMID:34122009 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Atxn10 ataxin 10 increases expression ISO Clozapine results in increased expression of ATXN10 protein CTD PMID:34122009 NCBI chr 7:116,441,768...116,565,093
Ensembl chr 7:116,441,613...116,565,087 		JBrowse link
G Axin2 axin 2 decreases expression EXP Clozapine results in decreased expression of AXIN2 mRNA CTD PMID:16715494 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bace2 beta-secretase 2 increases expression ISO Clozapine results in increased expression of BACE2 protein CTD PMID:36482696 NCBI chr11:36,707,447...36,789,550
Ensembl chr11:36,707,458...36,789,546 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
decreases expression		 ISO
EXP		 Clozapine results in increased expression of BAX mRNA; Clozapine results in increased expression of BAX protein
CSF3 protein inhibits the reaction [Clozapine results in increased expression of BAX mRNA]
Clozapine results in decreased expression of BAX protein		 CTD PMID:16160616 PMID:17069804 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Baz1b bromodomain adjacent to zinc finger domain, 1B multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of BAZ1B protein CTD PMID:34122009 NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426 		JBrowse link
G Bcar1 BCAR1 scaffold protein, Cas family member decreases expression ISO Clozapine results in decreased expression of BCAR1 protein CTD PMID:34122009 NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Clozapine results in increased expression of BCL2 mRNA; Clozapine results in increased expression of BCL2 protein CTD PMID:15126120 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l14 Bcl2-like 14 decreases expression ISO Clozapine results in decreased expression of BCL2L14 protein CTD PMID:34122009 NCBI chr 4:167,217,561...167,258,723
Ensembl chr 4:167,219,871...167,258,086 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
increases expression		 EXP Clozapine results in decreased expression of BDNF mRNA
Clozapine results in increased expression of BDNF mRNA; Clozapine results in increased expression of BDNF protein		 CTD PMID:11488957 PMID:12478621 PMID:17442489 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like decreases expression EXP Clozapine results in decreased expression of BET1L mRNA CTD PMID:15860345 NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040 		JBrowse link
G Bik BCL2-interacting killer multiple interactions
increases expression		 ISO CSF3 protein inhibits the reaction [Clozapine results in increased expression of BIK mRNA] CTD PMID:16160616 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO Clozapine results in decreased expression of BPTF mRNA CTD PMID:14647396 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769 		JBrowse link
G Bzw1 basic leucine zipper and W2 domains 1 increases expression ISO Clozapine results in increased expression of BZW1 protein CTD PMID:34122009 NCBI chr 9:59,930,672...59,944,468
Ensembl chr 9:59,930,744...59,944,430 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A decreases expression ISO
EXP		 Clozapine results in decreased expression of CACNA1A mRNA CTD PMID:14647396 PMID:16715494 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Calcoco1 calcium binding and coiled coil domain 1 increases expression ISO Clozapine results in increased expression of CALCOCO1 protein CTD PMID:36482696 NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422 		JBrowse link
G Calm2 calmodulin 2 increases expression EXP Clozapine results in increased expression of CALM2 mRNA CTD PMID:19289156 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Calr calreticulin decreases expression ISO Clozapine results in decreased expression of CALR protein CTD PMID:34122009 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Calu calumenin decreases expression ISO Clozapine results in decreased expression of CALU protein CTD PMID:34122009 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression
increases expression		 ISO
EXP		 Clozapine results in decreased expression of CAMK2A mRNA
Clozapine results in increased expression of CAMK2A mRNA
Clozapine results in decreased expression of CAMK2A protein		 CTD PMID:15860345 PMID:17266109 PMID:19289156 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression EXP Clozapine results in decreased expression of CAMK2B mRNA CTD PMID:15860345 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression EXP Clozapine results in decreased expression of CAMK2D mRNA CTD PMID:15860345 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV increases expression
decreases expression		 EXP Clozapine results in increased expression of CAMK4 mRNA
Clozapine results in decreased expression of CAMK4 protein		 CTD PMID:15860345 PMID:19289156 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 decreases expression EXP Clozapine results in decreased expression of CAMKK1 protein CTD PMID:19289156 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression EXP Clozapine results in decreased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Canx calnexin decreases expression ISO Clozapine results in decreased expression of CANX protein CTD PMID:34122009 NCBI chr10:34,623,865...34,656,866
Ensembl chr10:34,625,191...34,656,821 		JBrowse link
G Cars1 cysteinyl-tRNA synthetase 1 increases expression ISO Clozapine results in increased expression of CARS1 protein CTD PMID:34122009 NCBI chr 1:198,753,689...198,796,016
Ensembl chr 1:198,753,691...198,795,941 		JBrowse link
G Cartpt CART prepropeptide decreases expression EXP Clozapine results in decreased expression of CARTPT mRNA CTD PMID:14696011 NCBI chr 2:31,255,098...31,257,452
Ensembl chr 2:31,255,098...31,290,713 		JBrowse link
G Casp1 caspase 1 increases activity ISO Clozapine results in increased activity of CASP1 protein CTD PMID:34935985 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO
EXP		 Clozapine results in increased activity of CASP3 protein
Palmitic Acid promotes the reaction [Clozapine results in increased activity of CASP3 protein]		 CTD PMID:22700542 PMID:24709159 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases activity
multiple interactions		 ISO Clozapine results in increased activity of CASP7 protein
Palmitic Acid promotes the reaction [Clozapine results in increased activity of CASP7 protein]		 CTD PMID:22700542 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Cat catalase multiple interactions ISO Clozapine inhibits the reaction [Corticosterone results in increased activity of CAT protein]; Clozapine inhibits the reaction [Lipopolysaccharides inhibits the reaction [Corticosterone results in increased activity of CAT protein]] CTD PMID:14730115 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccar1 cell division cycle and apoptosis regulator 1 increases expression ISO Clozapine results in increased expression of CCAR1 protein CTD PMID:34122009 NCBI chr20:30,685,916...30,728,531
Ensembl chr20:30,685,916...30,728,526 		JBrowse link
G Ccdc47 coiled-coil domain containing 47 increases expression
multiple interactions		 ISO Clozapine results in increased expression of CCDC47 protein
[Cuprizone co-treated with Clozapine] results in increased expression of CCDC47 protein		 CTD PMID:34122009 NCBI chr10:91,130,303...91,148,829
Ensembl chr10:91,130,303...91,148,881 		JBrowse link
G Cck cholecystokinin multiple interactions
increases expression		 EXP Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CCK mRNA]; Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CCK protein]
Clozapine results in increased expression of CCK mRNA		 CTD PMID:10974607 PMID:16567023 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Cckbr cholecystokinin B receptor increases expression ISO Clozapine results in increased expression of CCKBR mRNA CTD PMID:17266109 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Ccl1 C-C motif chemokine ligand 1 decreases expression ISO Clozapine results in decreased expression of CCL1 mRNA CTD PMID:17346280 NCBI chr10:67,128,331...67,131,109
Ensembl chr10:67,128,331...67,131,159 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Clozapine results in decreased expression of CCND1 mRNA CTD PMID:15860345 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 increases expression EXP Clozapine results in increased expression of CCND3 mRNA CTD PMID:15860345 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Clozapine results in increased expression of CCNL1 mRNA CTD PMID:15860345 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368 		JBrowse link
G Cct7 chaperonin containing TCP1 subunit 7 decreases expression ISO Clozapine results in decreased expression of CCT7 protein CTD PMID:34122009 NCBI chr 4:117,989,232...118,006,478
Ensembl chr 4:117,989,232...118,006,580 		JBrowse link
G Cd276 Cd276 molecule decreases expression ISO Clozapine results in decreased expression of CD276 protein CTD PMID:34122009 NCBI chr 8:58,937,751...58,968,082
Ensembl chr 8:58,937,751...58,968,380 		JBrowse link
G Cd63 Cd63 molecule increases expression ISO Clozapine results in increased expression of CD63 protein CTD PMID:36482696 NCBI chr 7:1,325,108...1,340,447
Ensembl chr 7:1,325,103...1,399,178 		JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase increases expression ISO Clozapine results in increased expression of CDIPT protein CTD PMID:34122009 NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP Clozapine results in increased expression of CDK4 mRNA CTD PMID:15860345 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression EXP Clozapine results in increased expression of CDK5 mRNA CTD PMID:15860345 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 increases expression ISO Clozapine results in increased expression of CDK5R1 mRNA CTD PMID:17266109 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions
increases expression		 ISO Berberine inhibits the reaction [Clozapine results in increased expression of CEBPA mRNA]; Berberine inhibits the reaction [Clozapine results in increased expression of CEBPA protein]
Clozapine results in increased expression of CEBPA mRNA; Clozapine results in increased expression of CEBPA protein		 CTD PMID:20564506 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Cenpv centromere protein V increases expression ISO Clozapine results in increased expression of CENPV protein CTD PMID:34122009 NCBI chr10:47,214,479...47,228,552
Ensembl chr10:47,214,490...47,228,761 		JBrowse link
G Cfap210 cilia and flagella associated protein 210 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of CFAP210 protein CTD PMID:34122009 NCBI chr 3:54,520,455...54,554,677
Ensembl chr 3:54,520,458...54,554,607 		JBrowse link
G Chchd2 coiled-coil-helix-coiled-coil-helix domain containing 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of CHCHD2 protein CTD PMID:34122009 NCBI chr12:26,828,738...26,834,762
Ensembl chr12:26,828,736...26,834,755 		JBrowse link
G Chd4 chromodomain helicase DNA binding protein 4 decreases expression ISO Clozapine results in decreased expression of CHD4 protein CTD PMID:34122009 NCBI chr 4:157,898,503...157,931,632
Ensembl chr 4:157,899,391...157,931,541 		JBrowse link
G Chga chromogranin A decreases expression
increases expression		 EXP Clozapine results in decreased expression of CHGA mRNA
Clozapine results in increased expression of CHGA mRNA		 CTD PMID:12437575 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chl1 cell adhesion molecule L1-like decreases expression ISO Clozapine results in decreased expression of CHL1 mRNA CTD PMID:14647396 NCBI chr 4:136,291,504...136,505,830
Ensembl chr 4:136,291,463...136,503,265 		JBrowse link
G Chn1 chimerin 1 decreases expression ISO Clozapine results in decreased expression of CHN1 mRNA CTD PMID:14647396 NCBI chr 3:58,509,822...58,676,462
Ensembl chr 3:58,510,536...58,676,490 		JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression ISO Clozapine results in increased expression of CHORDC1 protein CTD PMID:34122009 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 affects binding
increases expression
multiple interactions		 ISO
EXP		 Clozapine analog binds to CHRM1 protein; Clozapine binds to CHRM1 protein
Clozapine results in increased expression of CHRM1 protein
Clozapine inhibits the reaction [Dextroamphetamine results in decreased expression of CHRM1 protein]		 CTD PMID:11997696 PMID:16983399 PMID:18806925 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Ckap4 cytoskeleton-associated protein 4 increases expression ISO Clozapine results in increased expression of CKAP4 protein CTD PMID:34122009 NCBI chr 7:19,230,814...19,238,914
Ensembl chr 7:19,230,203...19,238,914 		JBrowse link
G Clic1 chloride intracellular channel 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of CLIC1 protein CTD PMID:34122009 NCBI chr20:3,764,867...3,773,711
Ensembl chr20:3,761,461...3,773,712 		JBrowse link
G Clic4 chloride intracellular channel 4 increases expression ISO Clozapine results in increased expression of CLIC4 protein CTD PMID:34122009 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452 		JBrowse link
G Clock clock circadian regulator affects response to substance ISO CLOCK gene SNP affects the susceptibility to Clozapine CTD PMID:15331141 NCBI chr14:31,908,542...31,992,673
Ensembl chr14:31,908,566...31,990,400 		JBrowse link
G Clta clathrin, light chain A decreases expression EXP Clozapine results in decreased expression of CLTA mRNA CTD PMID:15860345 NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472 		JBrowse link
G Cltb clathrin, light chain B decreases expression EXP Clozapine results in decreased expression of CLTB mRNA CTD PMID:15860345 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression
increases expression		 ISO Clozapine results in decreased expression of CNP mRNA
Clozapine results in decreased expression of CNP protein
Clozapine results in increased expression of CNP mRNA		 CTD PMID:17266109 PMID:34122009 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Coil coilin increases expression EXP Clozapine results in increased expression of COIL mRNA CTD PMID:16715494 NCBI chr10:73,789,077...73,810,378
Ensembl chr10:73,789,488...73,810,393 		JBrowse link
G Col5a2 collagen type V alpha 2 chain multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of COL5A2 protein CTD PMID:34122009 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Comt catechol-O-methyltransferase multiple interactions
affects response to substance
increases response to substance		 EXP
ISO		 [tolcapone results in decreased activity of COMT protein] promotes the reaction [Clozapine results in increased abundance of Dopamine]
COMT protein affects the susceptibility to Clozapine
COMT gene polymorphism results in increased susceptibility to Clozapine		 CTD PMID:15190105 PMID:17123785 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cops3 COP9 signalosome subunit 3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of COPS3 protein CTD PMID:34122009 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597 		JBrowse link
G Coro1b coronin 1B decreases expression ISO Clozapine results in decreased expression of CORO1B protein CTD PMID:34122009 NCBI chr 1:201,442,977...201,448,416
Ensembl chr 1:201,443,014...201,448,416 		JBrowse link
G Cplx2 complexin 2 decreases expression ISO Clozapine results in decreased expression of CPLX2 mRNA CTD PMID:17266109 NCBI chr17:10,219,577...10,292,835
Ensembl chr17:10,222,347...10,293,855 		JBrowse link
G Cpn1 carboxypeptidase N subunit 1 increases expression EXP Clozapine results in increased expression of CPN1 mRNA CTD PMID:16715494 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465 		JBrowse link
G Cpne1 copine 1 decreases expression ISO Clozapine results in decreased expression of CPNE1 protein CTD PMID:34122009 NCBI chr 3:144,587,531...144,629,911
Ensembl chr 3:144,588,995...144,598,636 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions EXP [Clozapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased activity of CPT2 protein; [Clozapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased expression of CPT2 mRNA CTD PMID:23226405 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
decreases phosphorylation		 ISO Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of CREB1 protein]
Clozapine results in decreased phosphorylation of CREB1 protein		 CTD PMID:12871586 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Clozapine results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression EXP Clozapine results in decreased expression of CRHBP mRNA CTD PMID:16715494 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
G Crp C-reactive protein increases expression ISO Clozapine results in increased expression of CRP protein CTD PMID:17685758 NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178 		JBrowse link
G Csf3 colony stimulating factor 3 multiple interactions ISO CSF3 protein inhibits the reaction [Clozapine results in increased expression of BAX mRNA]; CSF3 protein inhibits the reaction [Clozapine results in increased expression of BIK mRNA]; CSF3 protein inhibits the reaction [Clozapine results in increased expression of TP53 mRNA] CTD PMID:16160616 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Clozapine results in decreased expression of CSNK2A1 mRNA CTD PMID:16715494 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Cst3 cystatin C increases expression ISO Clozapine results in increased expression of CST3 mRNA CTD PMID:14647396 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Cstf1 cleavage stimulation factor subunit 1 decreases expression ISO Clozapine results in decreased expression of CSTF1 protein CTD PMID:34122009 NCBI chr 3:161,144,522...161,156,294
Ensembl chr 3:161,144,548...161,156,300 		JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 decreases expression ISO Clozapine results in decreased expression of CSTF2 protein CTD PMID:34122009 NCBI chr  X:97,253,559...97,279,476
Ensembl chr  X:97,253,586...97,279,476 		JBrowse link
G Ctbp1 C-terminal binding protein 1 increases expression ISO Clozapine results in increased expression of CTBP1 protein CTD PMID:34122009 NCBI chr14:77,455,580...77,482,821
Ensembl chr14:77,455,696...77,482,821 		JBrowse link
G Ctnnb1 catenin beta 1 increases expression
multiple interactions		 EXP Clozapine results in increased expression of CTNNB1 protein
DRD2 protein affects the reaction [Clozapine results in increased expression of CTNNB1 protein]		 CTD PMID:16144542 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctrl chymotrypsin-like increases expression EXP Clozapine results in increased expression of CTRL mRNA CTD PMID:16715494 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Ctsk cathepsin K increases expression EXP Clozapine results in increased expression of CTSK mRNA CTD PMID:16715494 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cttn cortactin increases expression ISO Clozapine results in increased expression of CTTN protein CTD PMID:34122009 NCBI chr 1:199,599,710...199,635,254
Ensembl chr 1:199,599,710...199,635,164 		JBrowse link
G Cul2 cullin 2 increases expression ISO Clozapine results in increased expression of CUL2 protein CTD PMID:34122009 NCBI chr17:54,169,093...54,210,197
Ensembl chr17:54,169,086...54,209,968 		JBrowse link
G Cul3 cullin 3 increases expression ISO Clozapine results in increased expression of CUL3 protein CTD PMID:34122009 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 decreases expression
decreases secretion
multiple interactions
increases secretion		 ISO
EXP		 Clozapine results in decreased expression of CXCL1 mRNA
Clozapine results in decreased secretion of CXCL1 protein
belnacasan inhibits the reaction [Clozapine results in increased secretion of CXCL1 protein]		 CTD PMID:17346280 PMID:34935985 PMID:36482696 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases secretion ISO Clozapine results in decreased secretion of CXCL10 protein CTD PMID:36482696 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 decreases expression
decreases secretion		 ISO Clozapine results in decreased expression of CXCL1 mRNA
Clozapine results in decreased secretion of CXCL1 protein		 CTD PMID:17346280 PMID:36482696 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxhxorf49 similar to human chromosome X open reading frame 49 increases expression ISO Clozapine results in increased expression of CXORF49 protein CTD PMID:34122009 NCBI chr  X:66,911,430...66,915,407
Ensembl chr  X:66,911,431...66,915,293 		JBrowse link
G Cyb5b cytochrome b5 type B increases expression EXP Clozapine results in increased expression of CYB5B mRNA CTD PMID:19441803 NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249 		JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 increases expression ISO Clozapine results in increased expression of CYB5R1 protein CTD PMID:34122009 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases activity
increases metabolic processing		 EXP
ISO		 Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]
Clozapine results in decreased activity of CYP1A1 protein
CYP1A1 protein results in increased metabolism of Clozapine		 CTD PMID:18493746 PMID:18809730 PMID:33814510 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases response to substance
multiple interactions
increases metabolic processing
increases expression
affects metabolic processing
affects response to substance
decreases metabolic processing		 ISO
EXP		 CYP1A2 gene SNP results in decreased susceptibility to Clozapine
Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]
CYP1A2 protein results in increased metabolism of Clozapine
Clozapine results in increased expression of CYP1A2 mRNA
CYP1A2 gene polymorphism affects the metabolism of Clozapine; CYP1A2 protein affects the metabolism of Clozapine; CYP1A2 protein polymorphism affects the metabolism of Clozapine
[Ciprofloxacin results in decreased activity of CYP1A2 protein] which results in increased abundance of Clozapine; [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine; Clozapine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A2 protein]; Smoke affects the reaction [CYP1A2 gene polymorphism affects the metabolism of Clozapine]; Smoke promotes the reaction [CYP1A2 protein results in increased metabolism of Clozapine]
CYP1A2 gene SNP affects the susceptibility to Clozapine; CYP1A2 protein affects the susceptibility to Clozapine
CYP1A2 gene SNP results in increased metabolism of Clozapine; CYP1A2 protein results in increased metabolism of Clozapine
CYP1A2 gene SNP results in decreased metabolism of Clozapine		 CTD PMID:11151749 PMID:11763009 PMID:12919186 PMID:12969762 PMID:15206669 More... NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases metabolic processing
decreases activity		 ISO CYP1B1 protein results in increased metabolism of Clozapine
Clozapine results in decreased activity of CYP1B1 protein		 CTD PMID:18809730 PMID:33814510 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
increases metabolic processing		 ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine
CYP2C19 protein results in increased metabolism of Clozapine		 CTD PMID:18809730 PMID:23397584 PMID:27320963 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 increases metabolic processing ISO CYP2C8 protein results in increased metabolism of Clozapine CTD PMID:18809730 PMID:27320963
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing
increases metabolic processing
multiple interactions		 ISO CYP2D6 protein affects the metabolism of Clozapine
CYP2D6 protein results in increased metabolism of Clozapine
[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine		 CTD PMID:15286053 PMID:18809730 PMID:23397584 PMID:27320963 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2j4 cytochrome P450, family 2, subfamily j, polypeptide 4 increases metabolic processing ISO CYP2J2 protein results in increased metabolism of Clozapine CTD PMID:18809730 NCBI chr 5:111,179,981...111,207,490
Ensembl chr 5:111,178,703...111,244,794 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing
affects metabolic processing
multiple interactions		 ISO CYP3A4 protein results in increased metabolism of Clozapine
CYP3A4 protein affects the metabolism of Clozapine
[CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Clozapine; Clozapine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Clozapine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]		 CTD PMID:15286053 PMID:18809730 PMID:21402137 PMID:23397584 PMID:27320963 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases metabolic processing ISO CYP3A5 protein results in increased metabolism of Clozapine CTD PMID:18809730 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Dab1 DAB adaptor protein 1 increases expression EXP Clozapine results in increased expression of DAB1 mRNA CTD PMID:19359144 NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552 		JBrowse link
G Dab2 DAB adaptor protein 2 increases expression ISO Clozapine results in increased expression of DAB2 protein CTD PMID:36482696 NCBI chr 2:55,514,692...55,567,476
Ensembl chr 2:55,514,700...55,567,476 		JBrowse link
G Daglb diacylglycerol lipase, beta increases expression ISO Clozapine results in increased expression of DAGLB protein CTD PMID:36482696 NCBI chr12:11,059,732...11,102,170
Ensembl chr12:11,059,732...11,102,154 		JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression ISO Clozapine results in decreased expression of DCAF6 mRNA CTD PMID:14647396 NCBI chr13:77,626,257...77,727,645
Ensembl chr13:77,626,307...77,727,512 		JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression ISO
EXP		 Clozapine results in increased expression of DCLK1 mRNA CTD PMID:15860345 PMID:18797397 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956 		JBrowse link
G Ddc dopa decarboxylase multiple interactions
increases expression		 ISO Clozapine results in increased expression of and results in increased activity of DDC protein
Clozapine results in increased expression of DDC mRNA		 CTD PMID:16415089 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Ddx46 DEAD-box helicase 46 increases expression ISO Clozapine results in increased expression of DDX46 protein CTD PMID:34122009 NCBI chr17:8,942,070...8,988,440
Ensembl chr17:8,944,454...8,988,439 		JBrowse link
G Dennd10 DENN domain containing 10 increases expression EXP Clozapine results in increased expression of DENND10 mRNA CTD PMID:16715494 NCBI chr 1:259,950,955...259,974,459
Ensembl chr 1:259,950,866...259,974,455 		JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO Clozapine results in increased expression of DEPP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Dgcr6 DiGeorge syndrome critical region gene 6 decreases expression ISO Clozapine results in decreased expression of DGCR6 protein CTD PMID:34122009 NCBI chr11:82,927,725...82,932,823
Ensembl chr11:82,927,725...82,932,823 		JBrowse link
G Dgka diacylglycerol kinase, alpha decreases expression EXP Clozapine results in decreased expression of DGKA mRNA CTD PMID:15860345 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110 		JBrowse link
G Dhcr24 24-dehydrocholesterol reductase increases expression ISO Clozapine results in increased expression of DHCR24 protein CTD PMID:34122009 NCBI chr 5:121,344,552...121,371,124
Ensembl chr 5:121,344,575...121,371,137 		JBrowse link
G Dhcr7 7-dehydrocholesterol reductase increases expression ISO Clozapine results in increased expression of DHCR7 mRNA CTD PMID:17052361 NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055 		JBrowse link
G Dhx30 DExH-box helicase 30 increases expression ISO Clozapine results in increased expression of DHX30 protein CTD PMID:34122009 NCBI chr 8:110,064,751...110,096,954
Ensembl chr 8:110,064,752...110,097,381 		JBrowse link
G Dhx38 DEAH-box helicase 38 decreases expression ISO Clozapine results in decreased expression of DHX38 protein CTD PMID:34122009 NCBI chr19:37,512,893...37,530,135
Ensembl chr19:37,512,891...37,530,140 		JBrowse link
G Disc1 DISC1 scaffold protein decreases response to substance
affects response to substance		 ISO DISC1 gene mutant form results in decreased susceptibility to Clozapine
DISC1 protein affects the susceptibility to Clozapine		 CTD PMID:20531374 NCBI chr19:53,014,201...53,223,617
Ensembl chr19:53,014,616...53,219,778 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression
increases expression		 EXP
ISO		 Clozapine results in decreased expression of DLAT mRNA
Clozapine results in increased expression of DLAT protein		 CTD PMID:15860345 PMID:34122009 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Clozapine results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase decreases expression ISO Clozapine results in decreased expression of DLST protein CTD PMID:34122009 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Dnah11 dynein, axonemal, heavy chain 11 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of DNAH11 protein CTD PMID:34122009 NCBI chr 6:138,839,175...139,155,554
Ensembl chr 6:138,839,177...139,155,536 		JBrowse link
G Dnaja3 DnaJ heat shock protein family (Hsp40) member A3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of DNAJA3 protein CTD PMID:34122009 NCBI chr10:10,854,732...10,880,171
Ensembl chr10:10,854,732...10,880,161 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 increases expression ISO Clozapine results in increased expression of DNAJB11 protein CTD PMID:34122009 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407 		JBrowse link
G Dpf1 double PHD fingers 1 affects expression ISO Clozapine affects the expression of DPF1 mRNA CTD PMID:14647396 NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950 		JBrowse link
G Dpp3 dipeptidylpeptidase 3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of DPP3 protein CTD PMID:34122009 NCBI chr 1:202,204,683...202,228,501
Ensembl chr 1:202,204,693...202,228,541 		JBrowse link
G Dpysl3 dihydropyrimidinase-like 3 decreases expression ISO Clozapine results in decreased expression of DPYSL3 protein CTD PMID:34122009 NCBI chr18:35,374,427...35,480,228
Ensembl chr18:35,377,181...35,480,157 		JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 decreases expression ISO Clozapine results in decreased expression of DPYSL4 protein CTD PMID:34122009 NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914 		JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO Clozapine results in decreased expression of DR1 protein CTD PMID:34122009 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638 		JBrowse link
G Drd1 dopamine receptor D1 affects binding
decreases expression
affects response to substance		 ISO
EXP		 Clozapine binds to DRD1 protein
Clozapine results in decreased expression of DRD1 mRNA
Clozapine analog binds to DRD1 protein
DRD1 gene polymorphism affects the susceptibility to Clozapine; DRD1 protein affects the susceptibility to Clozapine		 CTD PMID:1352677 PMID:9723970 PMID:11997696 PMID:17092969 PMID:17266109 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects binding
affects response to substance
decreases expression
increases response to substance		 ISO
EXP		 [Clozapine co-treated with DRD2 gene polymorphism] results in increased secretion of PRL protein
Clozapine binds to DRD2 protein
DRD2 protein affects the susceptibility to Clozapine
Clozapine results in decreased expression of DRD2 mRNA
Clozapine analog binds to DRD2 protein; Clozapine binds to DRD2 protein
[Clozapine binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein; Bromocriptine promotes the reaction [Clozapine results in decreased expression of DRD2 mRNA]; Clozapine binds to and results in decreased activity of DRD2 protein; Clozapine promotes the reaction [Dopamine binds to DRD2 protein]; DRD2 protein affects the reaction [Clozapine results in increased expression of CTNNB1 protein]; DRD2 protein affects the reaction [Clozapine results in increased expression of DVL3 protein]; DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3A protein]; DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3B protein]
[Clozapine co-treated with Bromocriptine] results in decreased expression of DRD2 mRNA
Clozapine binds to DRD2 protein alternative form
DRD2 gene SNP results in increased susceptibility to Clozapine
DRD2 gene affects the susceptibility to Clozapine; DRD2 gene polymorphism affects the susceptibility to Clozapine		 CTD PMID:1352677 PMID:9723970 PMID:11997696 PMID:12476322 PMID:15286066 More... NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 affects response to substance
multiple interactions
decreases response to substance		 ISO DRD3 protein affects the susceptibility to Clozapine
DRD3 protein affects the reaction [Clozapine results in increased expression of FOSB protein alternative form]
DRD3 gene polymorphism results in decreased susceptibility to Clozapine		 CTD PMID:15579174 PMID:20029384 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 affects binding
multiple interactions
affects response to substance		 ISO
EXP		 Clozapine binds to DRD4 protein
Clozapine binds to Drd4 protein
Clozapine inhibits the reaction [Dopamine results in increased activity of DRD4 protein]
Clozapine analog binds to DRD4 protein
DRD4 gene polymorphism affects the susceptibility to Clozapine		 CTD
RGD		 PMID:11997696 PMID:16223700 PMID:31323226 PMID:8078498 RGD:7248459 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Drp2 dystrophin related protein 2 increases expression EXP Clozapine results in increased expression of DRP2 mRNA alternative form CTD PMID:16715494 NCBI chr  X:97,607,577...97,658,117
Ensembl chr  X:97,607,719...97,655,684 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 increases response to substance
affects response to substance		 ISO DTNBP1 gene polymorphism results in increased susceptibility to Clozapine
DTNBP1 protein affects the susceptibility to Clozapine		 CTD PMID:19369910 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Clozapine results in decreased expression of DUSP1 mRNA CTD PMID:15860345 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP Clozapine results in decreased expression of DUSP6 mRNA CTD PMID:15860345 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 increases expression
multiple interactions		 EXP Clozapine results in increased expression of DVL3 protein
DRD2 protein affects the reaction [Clozapine results in increased expression of DVL3 protein]		 CTD PMID:16144542 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Dync1li1 dynein cytoplasmic 1 light intermediate chain 1 decreases expression ISO Clozapine results in decreased expression of DYNC1LI1 protein CTD PMID:34122009 NCBI chr 8:114,376,649...114,410,297
Ensembl chr 8:114,376,662...114,410,934 		JBrowse link
G Dync1li2 dynein, cytoplasmic 1 light intermediate chain 2 decreases expression ISO Clozapine results in decreased expression of DYNC1LI2 protein CTD PMID:34122009 NCBI chr19:531,783...554,670
Ensembl chr19:531,812...554,670 		JBrowse link
G Edc4 enhancer of mRNA decapping 4 increases expression ISO Clozapine results in increased expression of EDC4 protein CTD PMID:34122009 NCBI chr19:33,774,062...33,786,054
Ensembl chr19:33,774,055...33,787,758 		JBrowse link
G Eef1a2 eukaryotic translation elongation factor 1 alpha 2 increases expression ISO Clozapine results in increased expression of EEF1A2 protein CTD PMID:34122009 NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Eef1d eukaryotic translation elongation factor 1 delta decreases expression ISO Clozapine results in decreased expression of EEF1D protein CTD PMID:34122009 NCBI chr 7:107,581,930...107,596,735
Ensembl chr 7:107,581,930...107,608,799 		JBrowse link
G Egr1 early growth response 1 decreases expression EXP Clozapine results in decreased expression of EGR1 mRNA; Clozapine results in decreased expression of EGR1 protein CTD PMID:17028028 PMID:18208916 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 affects expression
decreases expression		 ISO
EXP		 Clozapine affects the expression of EGR2 mRNA
Clozapine results in decreased expression of EGR2 protein		 CTD PMID:17028028 PMID:19401217 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Egr3 early growth response 3 affects response to substance ISO EGR3 protein affects the susceptibility to Clozapine CTD PMID:17637609 NCBI chr15:45,150,335...45,156,052
Ensembl chr15:45,150,567...45,154,627 		JBrowse link
G Eif2s3 eukaryotic translation initiation factor 2 subunit gamma increases expression ISO Clozapine results in increased expression of EIF2S3 protein CTD PMID:34122009 NCBI chr  X:58,916,513...58,939,923
Ensembl chr  X:58,917,490...58,940,686 		JBrowse link
G Eif3c eukaryotic translation initiation factor 3, subunit C multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of EIF3C protein CTD PMID:34122009 NCBI chr 1:181,134,604...181,152,489
Ensembl chr 1:181,134,604...181,152,493 		JBrowse link
G Eif3j eukaryotic translation initiation factor 3, subunit J increases expression ISO Clozapine results in increased expression of EIF3J protein CTD PMID:34122009 NCBI chr 3:108,985,103...109,007,341
Ensembl chr 3:108,985,118...109,007,953 		JBrowse link
G Eif3m eukaryotic translation initiation factor 3, subunit M multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of EIF3M protein CTD PMID:34122009 NCBI chr 3:91,424,754...91,442,358
Ensembl chr 3:91,416,325...91,442,392 		JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of EIF4A3 protein CTD PMID:34122009 NCBI chr10:104,549,038...104,559,032
Ensembl chr10:104,549,038...104,559,057 		JBrowse link
G Eif4e eukaryotic translation initiation factor 4E multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of EIF4E protein CTD PMID:34122009 NCBI chr 2:227,066,519...227,099,261
Ensembl chr 2:227,066,673...227,098,683 		JBrowse link
G Eif5b eukaryotic translation initiation factor 5B increases expression ISO Clozapine results in increased expression of EIF5B protein CTD PMID:34122009 NCBI chr 9:40,222,769...40,277,482
Ensembl chr 9:40,222,898...40,277,482 		JBrowse link
G Eif6 eukaryotic translation initiation factor 6 decreases expression ISO Clozapine results in decreased expression of EIF6 protein CTD PMID:34122009 NCBI chr 3:144,325,038...144,331,396
Ensembl chr 3:144,325,036...144,331,401 		JBrowse link
G Elk1 ETS transcription factor ELK1 decreases phosphorylation ISO Clozapine results in decreased phosphorylation of ELK1 protein CTD PMID:12871586 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Eno1 enolase 1 increases expression EXP Clozapine results in increased expression of ENO1 mRNA CTD PMID:15860345 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Eno3 enolase 3 increases expression ISO Clozapine results in increased expression of ENO3 protein CTD PMID:34122009 NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921 		JBrowse link
G Epha7 Eph receptor A7 increases expression ISO Clozapine results in increased expression of EPHA7 mRNA CTD PMID:17266109 NCBI chr 5:42,975,353...43,128,703
Ensembl chr 5:42,975,405...43,127,112 		JBrowse link
G Ephb3 Eph receptor B3 increases expression ISO Clozapine results in increased expression of EPHB3 protein CTD PMID:34122009 NCBI chr11:79,840,668...79,859,345
Ensembl chr11:79,840,668...79,859,370 		JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 decreases expression ISO Clozapine results in decreased expression of ERAP1 protein CTD PMID:34122009 NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 affects phosphorylation EXP Clozapine affects the phosphorylation of ERBB2 protein CTD PMID:26961615 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions EXP Clozapine results in increased expression of and results in increased phosphorylation of ERBB4 protein CTD PMID:26961615 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Erh ERH, mRNA splicing and mitosis factor increases expression ISO Clozapine results in increased expression of ERH protein CTD PMID:34122009 NCBI chr 6:100,280,933...100,291,200
Ensembl chr 6:100,280,930...100,291,210 		JBrowse link
G Erp44 endoplasmic reticulum protein 44 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of ERP44 protein CTD PMID:34122009 NCBI chr 5:62,516,550...62,610,762
Ensembl chr 5:62,516,551...62,610,761 		JBrowse link
G Ewsr1 EWS RNA-binding protein 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of EWSR1 protein CTD PMID:34122009 NCBI chr14:79,965,365...79,994,108
Ensembl chr14:79,965,368...79,994,544 		JBrowse link
G Exosc4 exosome component 4 increases expression ISO Clozapine results in increased expression of EXOSC4 protein CTD PMID:34122009 NCBI chr 7:108,047,831...108,050,573
Ensembl chr 7:108,047,831...108,050,573 		JBrowse link
G Ezr ezrin decreases expression ISO Clozapine results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Clozapine results in increased expression of FABP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fan1 FANCD2 and FANCI associated nuclease 1 increases expression ISO Clozapine results in increased expression of FAN1 protein CTD PMID:34122009 NCBI chr 1:117,915,323...117,945,044
Ensembl chr 1:117,917,099...117,944,977 		JBrowse link
G Farsa phenylalanyl-tRNA synthetase subunit alpha increases expression ISO Clozapine results in increased expression of FARSA protein CTD PMID:34122009 NCBI chr19:23,291,409...23,300,985
Ensembl chr19:23,268,869...23,300,980 		JBrowse link
G Farsb phenylalanyl-tRNA synthetase subunit beta increases expression ISO Clozapine results in increased expression of FARSB protein CTD PMID:34122009 NCBI chr 9:79,887,852...79,947,082
Ensembl chr 9:79,887,842...79,947,045 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Clozapine co-treated with Berberine] results in decreased expression of FAS mRNA CTD PMID:20564506 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand multiple interactions ISO [Clozapine analog co-treated with Hydrogen Peroxide] results in increased expression of FASLG mRNA; [Clozapine co-treated with Hydrogen Peroxide co-treated with Tretinoin] results in increased expression of FASLG mRNA CTD PMID:16510162 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fasn fatty acid synthase increases expression ISO Clozapine results in increased expression of FASN mRNA CTD PMID:16027736 PMID:17052361 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fdps farnesyl diphosphate synthase increases expression ISO Clozapine results in increased expression of FDPS mRNA CTD PMID:17052361 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Fen1 flap structure-specific endonuclease 1 increases expression ISO Clozapine results in increased expression of FEN1 protein CTD PMID:34122009 NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression EXP Clozapine results in increased expression of FGF2 mRNA CTD PMID:11264663 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgl1 fibrinogen-like 1 increases expression ISO Clozapine results in increased expression of FGL1 protein CTD PMID:36482696 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Fhod1 formin homology 2 domain containing 1 decreases expression ISO Clozapine results in decreased expression of FHOD1 protein CTD PMID:34122009 NCBI chr19:33,206,492...33,225,448
Ensembl chr19:33,206,492...33,225,356 		JBrowse link
G Fkbp8 FKBP prolyl isomerase 8 decreases expression ISO Clozapine results in decreased expression of FKBP8 protein CTD PMID:34122009 NCBI chr16:18,895,608...18,902,648
Ensembl chr16:18,893,576...18,902,612 		JBrowse link
G Flot2 flotillin 2 increases expression ISO Clozapine results in increased expression of FLOT2 protein CTD PMID:34122009 NCBI chr10:62,926,047...62,947,759
Ensembl chr10:62,920,665...62,947,756 		JBrowse link
G Fmo1 flavin containing dimethylaniline monoxygenase 1 increases metabolic processing ISO FMO1 protein results in increased metabolism of Clozapine CTD PMID:18809730 NCBI chr13:75,182,184...75,214,439
Ensembl chr13:75,182,176...75,214,647 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases metabolic processing ISO FMO3 protein results in increased metabolism of Clozapine CTD PMID:18809730 PMID:27320963 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Clozapine results in increased expression of FNDC4 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression		 EXP
ISO		 Clozapine affects the reaction [Haloperidol results in increased expression of FOS protein]; Cycloserine promotes the reaction [Clozapine results in increased expression of FOS mRNA]
Clozapine results in increased expression of FOS protein
Clozapine analog results in increased expression of FOS protein; Clozapine results in increased expression of FOS mRNA; Clozapine results in increased expression of FOS protein
Clozapine results in decreased expression of FOS protein		 CTD PMID:10435392 PMID:11166331 PMID:11440804 PMID:11997696 PMID:12093589 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions
decreases expression		 ISO
EXP		 Clozapine results in increased expression of FOSB protein alternative form
Clozapine results in increased expression of FOSB mRNA; Clozapine results in increased expression of FOSB protein
DRD3 protein affects the reaction [Clozapine results in increased expression of FOSB protein alternative form]
Clozapine results in decreased expression of FOSB mRNA		 CTD PMID:11259127 PMID:12093589 PMID:12243769 PMID:15579174 PMID:19695244 NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression EXP Clozapine results in increased expression of FOSL1 mRNA CTD PMID:18208916 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression EXP Clozapine results in increased expression of FOSL2 mRNA CTD PMID:12093589 PMID:12243769 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Foxp2 forkhead box P2 increases expression ISO Clozapine results in increased expression of FOXP2 mRNA CTD PMID:17266109 NCBI chr 4:43,133,827...43,712,442
Ensembl chr 4:43,133,912...43,711,683 		JBrowse link
G Fstl1 follistatin-like 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of FSTL1 protein CTD PMID:34122009 NCBI chr11:62,895,391...62,948,581
Ensembl chr11:62,779,783...62,948,677 		JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression ISO Clozapine results in increased expression of FUBP1 protein CTD PMID:34122009 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases expression ISO Clozapine results in decreased expression of G6PD protein CTD PMID:34122009 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gabarapl2 GABA type A receptor associated protein like 2 increases expression ISO Clozapine results in increased expression of GABARAPL2 protein CTD PMID:36482696 NCBI chr19:39,910,572...39,921,408
Ensembl chr19:39,910,534...39,924,628
Ensembl chr 8:39,910,534...39,924,628 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 decreases expression ISO Clozapine results in decreased expression of GABBR1 mRNA CTD PMID:17266109 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 increases expression ISO Clozapine results in increased expression of GABRA1 mRNA CTD PMID:17266109 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression EXP Clozapine results in increased expression of GABRB3 mRNA CTD PMID:18923069 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression
decreases methylation
multiple interactions		 ISO
EXP		 Clozapine results in increased expression of GAD1 mRNA
Clozapine results in decreased methylation of GAD1 promoter
Clozapine promotes the reaction [KMT2A protein binds to GAD1 promoter]; Valproic Acid promotes the reaction [Clozapine results in decreased methylation of GAD1 promoter]		 CTD PMID:12887421 PMID:15061247 PMID:17942719 PMID:18757738 PMID:18923069 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 increases expression ISO
EXP		 Clozapine results in increased expression of GAD2 mRNA CTD PMID:17266109 PMID:18923069 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP
ISO		 Clozapine results in increased expression of GAPDH mRNA
Clozapine results in increased expression of GAPDH protein		 CTD PMID:15860345 PMID:34122009 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gart phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase increases expression ISO Clozapine results in increased expression of GART protein CTD PMID:34122009 NCBI chr11:30,864,896...30,891,125
Ensembl chr11:30,865,889...30,891,125 		JBrowse link
G Gatm glycine amidinotransferase increases expression ISO Clozapine results in increased expression of GATM protein CTD PMID:34122009 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 decreases expression ISO Clozapine results in decreased expression of GCC2 protein CTD PMID:34122009 NCBI chr20:26,247,394...26,293,613
Ensembl chr20:26,247,404...26,293,613 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Clozapine results in increased expression of GDF15 protein CTD PMID:36482696 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Clozapine results in increased expression of GDPD3 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
increases expression		 EXP Clozapine results in decreased expression of GFAP protein
Clozapine results in increased expression of GFAP mRNA		 CTD PMID:18585900 PMID:19441803 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Ghitm growth hormone inducible transmembrane protein increases expression ISO Clozapine results in increased expression of GHITM protein CTD PMID:34122009 NCBI chr16:12,885,551...12,897,887
Ensembl chr16:12,885,553...12,897,879 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 decreases expression EXP Clozapine results in decreased expression of GIMAP5 mRNA CTD PMID:16715494 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Gip gastric inhibitory polypeptide increases expression EXP Clozapine results in increased expression of GIP mRNA; Clozapine results in increased expression of GIP protein CTD PMID:16402076 NCBI chr10:80,968,360...80,976,506
Ensembl chr10:80,968,352...80,976,503 		JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression EXP Clozapine results in increased expression of GJA1 protein CTD PMID:18585900 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Glp1r glucagon-like peptide 1 receptor multiple interactions
decreases expression		 EXP PGRMC1 protein inhibits the reaction [Clozapine results in decreased expression of GLP1R protein] CTD PMID:37087062 NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241 		JBrowse link
G Glrx3 glutaredoxin 3 increases expression ISO Clozapine results in increased expression of GLRX3 protein CTD PMID:34122009 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression ISO Clozapine results in decreased expression of GLUL protein CTD PMID:36482696 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gna12 G protein subunit alpha 12 decreases expression
increases expression		 EXP
ISO		 Clozapine results in decreased expression of GNA12 mRNA
Clozapine results in increased expression of GNA12 protein		 CTD PMID:15860345 PMID:34122009 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression EXP Clozapine results in decreased expression of GNAI1 mRNA CTD PMID:15860345 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP Clozapine results in decreased expression of GNAI2 mRNA CTD PMID:15860345 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 decreases expression EXP Clozapine results in decreased expression of GNAI3 mRNA CTD PMID:15860345 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gnas GNAS complex locus decreases expression
multiple interactions
increases expression		 EXP
ISO		 Clozapine results in decreased expression of GNAS mRNA
[Cuprizone co-treated with Clozapine] results in decreased expression of GNAS protein
Clozapine results in increased expression of GNAS protein		 CTD PMID:15860345 PMID:34122009 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnb3 G protein subunit beta 3 decreases response to substance
increases expression
affects response to substance
increases response to substance		 ISO
EXP		 GNB3 gene polymorphism results in decreased susceptibility to Clozapine
Clozapine results in increased expression of GNB3 protein
GNB3 protein affects the susceptibility to Clozapine
GNB3 gene polymorphism results in increased susceptibility to Clozapine		 CTD PMID:16139171 PMID:16141801 PMID:18855531 NCBI chr 4:157,639,468...157,645,171
Ensembl chr 4:157,639,469...157,645,173 		JBrowse link
G Golga3 golgin A3 increases expression ISO Clozapine results in increased expression of GOLGA3 protein CTD PMID:34122009 NCBI chr12:46,452,409...46,500,509
Ensembl chr12:46,454,870...46,500,509 		JBrowse link
G Golgb1 golgin B1 increases expression ISO Clozapine results in increased expression of GOLGB1 protein CTD PMID:34122009 NCBI chr11:63,843,179...63,900,665
Ensembl chr11:63,843,986...63,900,770 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 increases expression
multiple interactions		 EXP
ISO		 Clozapine results in increased expression of GOT2 mRNA
[Cuprizone co-treated with Clozapine] results in increased expression of GOT2 protein		 CTD PMID:15860345 PMID:34122009 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpd2 glycerol-3-phosphate dehydrogenase 2 decreases expression ISO Clozapine results in decreased expression of GPD2 protein CTD PMID:34122009 NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901 		JBrowse link
G Gpi glucose-6-phosphate isomerase increases expression ISO Clozapine results in increased expression of GPI protein CTD PMID:34122009 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions ISO [Chloroquine co-treated with Clozapine] results in increased secretion of GPT protein CTD PMID:36482696 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Clozapine results in increased expression of GPX1 mRNA CTD PMID:14647396 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 increases expression EXP Clozapine results in increased expression of GRIK2 mRNA CTD PMID:18923069 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 affects expression
decreases expression		 ISO
EXP		 Clozapine affects the expression of GRIK5 mRNA
Clozapine results in decreased expression of GRIK5 mRNA		 CTD PMID:14647396 PMID:18923069 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
increases expression		 ISO
EXP		 Clozapine results in decreased expression of GRIN1 mRNA
Clozapine results in increased expression of GRIN1 mRNA		 CTD PMID:12020038 PMID:12608697 PMID:17266109 PMID:18923069 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP Clozapine results in decreased expression of GRIN2A mRNA CTD PMID:12608697 PMID:18923069 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B decreases expression EXP Clozapine results in decreased expression of GRIN2B mRNA CTD PMID:18923069 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C decreases expression EXP Clozapine results in decreased expression of GRIN2C mRNA CTD PMID:18923069 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Clozapine results in decreased expression of GRK6 mRNA CTD PMID:16715494 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions		 EXP Clozapine results in increased expression of GSK3A protein
DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3A protein]		 CTD PMID:16144542 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
increases expression
multiple interactions		 ISO
EXP		 Clozapine results in increased phosphorylation of GSK3B protein
Clozapine results in increased expression of GSK3B protein
DRD2 protein affects the reaction [Clozapine results in increased expression of GSK3B protein]		 CTD PMID:16144542 PMID:19359144 PMID:19440698 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsta1 glutathione S-transferase alpha 1 decreases activity
increases glutathionylation		 ISO GSTA1 protein results in decreased activity of Clozapine
GSTA1 protein results in increased glutathionylation of Clozapine		 CTD PMID:20849150 NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases activity
increases expression
increases glutathionylation		 ISO
EXP		 GSTM1 protein results in decreased activity of Clozapine
Clozapine results in increased expression of GSTM1 mRNA
GSTM1 protein results in increased glutathionylation of Clozapine		 CTD PMID:15860345 PMID:20849150 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP Clozapine results in decreased expression of GSTM2 mRNA CTD PMID:15860345 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases activity
affects metabolic processing
increases glutathionylation
affects binding		 ISO Clozapine metabolite results in decreased activity of GSTP1 protein; GSTP1 protein results in decreased activity of Clozapine
GSTP1 protein affects the metabolism of Clozapine metabolite
GSTP1 protein results in increased glutathionylation of Clozapine
Clozapine metabolite binds to GSTP1 protein		 CTD PMID:20849150 PMID:21639118 PMID:24185126 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G H1f2 H1.2 linker histone, cluster member increases expression ISO Clozapine results in increased expression of H1-2 protein CTD PMID:34122009 NCBI chr17:41,391,106...41,392,597
Ensembl chr17:41,388,477...41,392,635 		JBrowse link
G H2ac18 H2A clustered histone 18 increases expression ISO Clozapine results in increased expression of H2AC18 mRNA CTD PMID:14647396 NCBI chr 2:183,808,398...183,808,992 JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Clozapine results in increased expression of H2AC20 protein CTD PMID:34122009 NCBI chr 2:183,779,879...183,780,357 JBrowse link
G H2aj H2A.J histone increases expression ISO Clozapine results in increased expression of H2AJ protein CTD PMID:34122009 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006 		JBrowse link
G Haao 3-hydroxyanthranilate 3,4-dioxygenase decreases expression ISO Clozapine results in decreased expression of HAAO protein CTD PMID:36482696 NCBI chr 6:10,845,235...10,864,863
Ensembl chr 6:10,845,771...10,864,877 		JBrowse link
G Hacd3 3-hydroxyacyl-CoA dehydratase 3 increases expression ISO Clozapine results in increased expression of HACD3 protein CTD PMID:34122009 NCBI chr 8:65,501,240...65,538,507
Ensembl chr 8:65,501,240...65,538,507 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta increases expression ISO Clozapine results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression ISO Clozapine results in increased expression of HARS1 protein CTD PMID:34122009 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740 		JBrowse link
G Hat1 histone acetyltransferase 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of HAT1 protein CTD PMID:34122009 NCBI chr 3:56,217,344...56,265,021
Ensembl chr 3:56,217,342...56,275,517 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of HCLS1 protein CTD PMID:34122009 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014 		JBrowse link
G Hdgfl2 HDGF like 2 increases expression ISO Clozapine results in increased expression of HDGFRP2 protein CTD PMID:34122009 NCBI chr 9:909,581...929,195
Ensembl chr 9:909,614...929,186 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression ISO Clozapine results in increased expression of HIGD1A mRNA CTD PMID:14647396 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Hmgb2 high mobility group box 2 increases expression ISO Clozapine results in increased expression of HMGB2 protein CTD PMID:34122009 NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase multiple interactions
increases expression
increases activity		 ISO [Clozapine results in increased activity of HMGCR protein] which results in increased abundance of Cholesterol; [Clozapine results in increased activity of HMGCR protein] which results in increased abundance of Triglycerides
Clozapine results in increased expression of HMGCR mRNA		 CTD PMID:16027736 PMID:17052361 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Clozapine results in increased expression of HMGCS1 mRNA CTD PMID:16027736 PMID:17052361 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Clozapine results in increased expression of HMOX1 mRNA CTD PMID:18227147 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpd heterogeneous nuclear ribonucleoprotein D decreases expression ISO Clozapine results in decreased expression of HNRNPD protein CTD PMID:34122009 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
G Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 decreases expression ISO Clozapine results in decreased expression of HNRNPH2 protein CTD PMID:36482696 NCBI chr  X:97,780,890...97,786,846
Ensembl chr  X:97,780,785...97,787,041 		JBrowse link
G Homer1 homer scaffold protein 1 increases expression
multiple interactions		 EXP Clozapine results in increased expression of HOMER1 mRNA
Cycloserine inhibits the reaction [Clozapine results in increased expression of HOMER1 mRNA]		 CTD PMID:12464447 PMID:15860345 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Hpcal1 hippocalcin-like 1 decreases expression EXP Clozapine results in decreased expression of HPCAL1 mRNA CTD PMID:12437575 NCBI chr 6:40,478,206...40,584,721
Ensembl chr 6:40,478,208...40,584,687 		JBrowse link
G Hpcal4 hippocalcin-like 4 affects expression EXP Clozapine affects the expression of HPCAL4 mRNA CTD PMID:12437575 NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416 		JBrowse link
G Hpn hepsin increases expression ISO Clozapine results in increased expression of HPN mRNA CTD PMID:15342952 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Hrh1 histamine receptor H 1 affects binding ISO Clozapine binds to HRH1 protein CTD PMID:16983399 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Hrh3 histamine receptor H3 multiple interactions EXP Clozapine binds to Hrh3 protein; Clozapine inhibits the reaction [N-methylhistamine binds to Hrh3 protein] RGD PMID:10869375 RGD:632981 NCBI chr 3:167,191,551...167,196,642
Ensembl chr 3:167,191,558...167,196,642 		JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 decreases expression ISO Clozapine results in decreased expression of HSD17B10 protein CTD PMID:34122009 NCBI chr  X:21,089,142...21,091,603
Ensembl chr  X:21,089,122...21,109,488 		JBrowse link
G Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 increases expression ISO Clozapine results in increased expression of HSD17B12 protein CTD PMID:34122009 NCBI chr 3:79,990,048...80,113,556
Ensembl chr 3:79,990,056...80,113,617 		JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 decreases expression ISO Clozapine results in decreased expression of HSPA9 protein CTD PMID:34122009 NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions
affects binding		 ISO
EXP		 Clozapine binds to and affects the activity of HTR1A protein
Clozapine binds to HTR1A protein		 CTD PMID:9723970 PMID:15482641 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D decreases expression EXP Clozapine results in decreased expression of HTR1D mRNA CTD PMID:16715494 NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases response to substance
affects binding
multiple interactions
decreases expression
decreases activity
affects response to substance
increases expression		 ISO
EXP		 HTR2A gene SNP results in increased susceptibility to Clozapine
Clozapine analog binds to HTR2A protein; Clozapine binds to HTR2A protein
Clozapine binds to and results in decreased activity of HTR2A protein; Clozapine inhibits the reaction [Ketanserin binds to HTR2A protein]
Clozapine results in decreased expression of HTR2A mRNA; Clozapine results in decreased expression of HTR2A protein
Clozapine results in decreased activity of HTR2A protein
[[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein; [Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein]; Clozapine binds to and results in decreased activity of HTR2A protein; Clozapine promotes the reaction [Phencyclidine results in decreased activity of HTR2A protein]
HTR2A protein affects the susceptibility to Clozapine
Clozapine results in increased expression of HTR2A mRNA		 CTD PMID:7520908 PMID:9723970 PMID:11997696 PMID:14751426 PMID:15380371 More... NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding
decreases expression
affects response to substance		 ISO
EXP		 Clozapine binds to HTR2C protein
Clozapine results in decreased expression of HTR2C mRNA
HTR2C gene polymorphism affects the susceptibility to Clozapine; HTR2C gene SNP affects the susceptibility to Clozapine; HTR2C promoter SNP affects the susceptibility to Clozapine; HTR2C protein affects the susceptibility to Clozapine		 CTD PMID:9723970 PMID:12668355 PMID:15635667 PMID:16983399 PMID:17868938 More... NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions
affects response to substance		 ISO Clozapine binds to and results in decreased activity of HTR3A protein
HTR3A protein affects the susceptibility to Clozapine		 CTD PMID:19696922 PMID:20168265 NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 multiple interactions
affects binding		 ISO Clozapine binds to and results in decreased activity of HTR6 protein
[Cuprizone co-treated with Clozapine] results in increased expression of HTR6 protein
Clozapine binds to HTR6 protein		 CTD PMID:11406289 PMID:16983399 PMID:34122009 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 affects binding
multiple interactions		 ISO Clozapine binds to HTR7 protein
[Clozapine binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP]; Clozapine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]		 CTD PMID:14578406 PMID:20827463 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Id2 inhibitor of DNA binding 2 increases expression EXP Clozapine results in increased expression of ID2 mRNA CTD PMID:12437575 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of IDH2 protein CTD PMID:34122009 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Clozapine results in decreased expression of IDI1 protein CTD PMID:34122009 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Ifng interferon gamma affects expression
decreases expression		 ISO Clozapine affects the expression of IFNG protein
Clozapine results in decreased expression of IFNG mRNA		 CTD PMID:17346280 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr1 interferon gamma receptor 1 increases expression ISO Clozapine results in increased expression of IFNGR1 protein CTD PMID:36482696 NCBI chr 1:14,333,167...14,351,799
Ensembl chr 1:14,333,187...14,351,785 		JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression ISO Clozapine results in decreased expression of IGF1 protein CTD PMID:11769361 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO Clozapine results in increased expression of IGFBP1 protein CTD PMID:36482696 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Il10 interleukin 10 decreases expression EXP Clozapine results in decreased expression of IL10 protein CTD PMID:24709159 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta increases secretion
multiple interactions		 EXP Clozapine results in increased secretion of IL1B protein
belnacasan inhibits the reaction [Clozapine results in increased secretion of IL1B protein]		 CTD PMID:34935985 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2ra interleukin 2 receptor subunit alpha increases secretion ISO Clozapine results in increased secretion of IL2RA protein CTD PMID:8067274 NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697 		JBrowse link
G Il5 interleukin 5 affects expression ISO Clozapine affects the expression of IL5 protein CTD PMID:17346280 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Ilkap ILK associated serine/threonine phosphatase decreases expression EXP Clozapine results in decreased expression of ILKAP mRNA CTD PMID:15860345 NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Clozapine results in decreased expression of INHA mRNA CTD PMID:16715494 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Clozapine results in increased expression of INHBE mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Ins2 insulin 2 affects secretion
increases expression		 ISO Clozapine affects the secretion of INS protein
Clozapine results in increased expression of INS protein		 CTD PMID:11769361 PMID:16601995 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Itga6 integrin subunit alpha 6 increases expression ISO Clozapine results in increased expression of ITGA6 protein CTD PMID:34122009 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428 		JBrowse link
G Jak1 Janus kinase 1 increases expression ISO Clozapine results in increased expression of JAK1 protein CTD PMID:36482696 NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions EXP [[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein; [Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein] CTD PMID:18976543 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit decreases expression
increases expression		 EXP Clozapine results in decreased expression of JUN mRNA
Clozapine results in increased expression of JUN mRNA		 CTD PMID:12093589 PMID:15860345 PMID:18208916 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit increases expression EXP Clozapine results in increased expression of JUNB mRNA CTD PMID:12093589 PMID:19695244 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Jund JunD proto-oncogene, AP-1 transcription factor subunit decreases expression EXP Clozapine results in decreased expression of JUND mRNA CTD PMID:12093589 NCBI chr16:18,734,121...18,735,799
Ensembl chr16:18,734,122...18,735,799 		JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 increases expression ISO Clozapine results in increased expression of KCNA1 mRNA CTD PMID:18797397 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Clozapine inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 decreases expression
increases expression		 ISO Clozapine results in decreased expression of KCNIP3 mRNA
Clozapine results in increased expression of KCNIP3 mRNA		 CTD PMID:17266109 PMID:18797397 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 decreases expression ISO Clozapine results in decreased expression of KCNK2 mRNA CTD PMID:15542763 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Clozapine results in decreased expression of KCTD12 protein CTD PMID:34122009 NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282 		JBrowse link
G Kdr kinase insert domain receptor increases expression ISO Clozapine results in increased expression of KDR protein CTD PMID:34122009 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Khdrbs1 KH RNA binding domain containing, signal transduction associated 1 decreases expression ISO Clozapine results in decreased expression of KHDRBS1 protein CTD PMID:34122009 NCBI chr 5:142,051,844...142,089,175
Ensembl chr 5:142,063,570...142,089,180 		JBrowse link
G Kif13b kinesin family member 13B increases expression ISO Clozapine results in increased expression of KIF13B protein CTD PMID:34122009 NCBI chr15:38,908,257...39,066,021
Ensembl chr15:38,924,624...39,084,879 		JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Clozapine results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413 		JBrowse link
G Kiz kizuna centrosomal protein multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of KIZ protein CTD PMID:34122009 NCBI chr 3:134,277,631...134,385,260
Ensembl chr 3:134,277,687...134,385,190 		JBrowse link
G Klhdc2 kelch domain containing 2 decreases expression ISO Clozapine results in decreased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr 6:87,777,183...87,791,609
Ensembl chr 6:87,777,183...87,804,187 		JBrowse link
G Kmt2a lysine methyltransferase 2A increases expression
decreases expression
multiple interactions		 ISO Clozapine results in increased expression of KMT2A mRNA
Clozapine results in decreased expression of KMT2A mRNA
Clozapine promotes the reaction [KMT2A protein binds to GAD1 promoter]		 CTD PMID:14647396 PMID:17942719 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Kpna4 karyopherin subunit alpha 4 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Clozapine] results in increased expression of KPNA4 protein
Clozapine results in increased expression of KPNA4 protein		 CTD PMID:34122009 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081 		JBrowse link
G Kremen1 kringle containing transmembrane protein 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of KREMEN1 protein CTD PMID:34122009 NCBI chr14:80,081,870...80,147,489
Ensembl chr14:80,084,403...80,147,516 		JBrowse link
G Lactb2 lactamase, beta 2 increases expression ISO Clozapine results in increased expression of LACTB2 protein CTD PMID:34122009 NCBI chr 5:5,569,080...5,591,843
Ensembl chr 5:5,569,067...5,596,429 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 increases expression ISO Clozapine results in increased expression of LAMP1 protein CTD PMID:34122009 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression ISO Clozapine results in increased expression of LAMTOR3 mRNA CTD PMID:14647396 NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607 		JBrowse link
G Larp7 La ribonucleoprotein 7, transcriptional regulator increases expression ISO Clozapine results in increased expression of LARP7 protein CTD PMID:34122009 NCBI chr 2:215,997,641...216,012,833
Ensembl chr 2:215,997,649...216,012,865 		JBrowse link
G Lcn1 lipocalin 1 decreases expression ISO Clozapine results in decreased expression of LCN1 protein CTD PMID:34122009 NCBI chr 3:9,532,860...9,537,859
Ensembl chr 3:9,532,915...9,536,577 		JBrowse link
G Ldhb lactate dehydrogenase B increases expression EXP Clozapine results in increased expression of LDHB mRNA CTD PMID:15860345 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression
multiple interactions		 ISO Clozapine results in increased expression of LDLR mRNA
Berberine inhibits the reaction [Clozapine results in increased expression of LDLR mRNA]		 CTD PMID:17052361 PMID:20564506 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Leap2 liver enriched antimicrobial peptide 2 increases expression ISO Clozapine results in increased expression of LEAP2 mRNA CTD PMID:17346280 NCBI chr10:37,580,172...37,581,244
Ensembl chr10:37,577,855...37,581,244 		JBrowse link
G Lemd2 LEM domain nuclear envelope protein 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of LEMD2 protein CTD PMID:34122009 NCBI chr20:5,282,397...5,296,621
Ensembl chr20:5,282,397...5,296,626 		JBrowse link
G Lep leptin affects response to substance
increases expression		 ISO
EXP		 LEP protein affects the susceptibility to Clozapine
Clozapine results in increased expression of LEP protein		 CTD PMID:16402076 PMID:17502770 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lgals8 galectin 8 increases expression ISO Clozapine results in increased expression of LGALS8 protein CTD PMID:36482696 NCBI chr17:58,024,652...58,052,764
Ensembl chr17:58,028,105...58,052,764 		JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO Clozapine results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Lmod2 leiomodin 2 increases expression ISO Clozapine results in increased expression of LMOD2 protein CTD PMID:34122009 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G Lpl lipoprotein lipase decreases expression
increases expression		 ISO Clozapine results in decreased expression of LPL mRNA; Clozapine results in decreased expression of LPL protein
Clozapine results in increased expression of LPL mRNA		 CTD PMID:17266109 PMID:19682446 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249 		JBrowse link
G Lrp10 LDL receptor related protein 10 increases expression ISO Clozapine results in increased expression of LRP10 protein CTD PMID:36482696 NCBI chr15:27,921,335...27,927,507
Ensembl chr15:27,920,259...27,927,505 		JBrowse link
G Lrpprc leucine-rich pentatricopeptide repeat containing increases expression ISO Clozapine results in increased expression of LRPPRC protein CTD PMID:34122009 NCBI chr 6:9,859,816...9,942,294
Ensembl chr 6:9,859,867...9,942,293 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 increases expression ISO Clozapine results in increased expression of LRRK2 protein CTD PMID:34122009 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Lss lanosterol synthase increases expression
multiple interactions		 ISO Clozapine results in increased expression of LSS mRNA
[Cuprizone co-treated with Clozapine] results in decreased expression of LSS protein		 CTD PMID:15342952 PMID:17175557 PMID:34122009 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Lta4h leukotriene A4 hydrolase decreases expression ISO Clozapine results in decreased expression of LTA4H protein CTD PMID:34122009 NCBI chr 7:27,969,796...28,001,600
Ensembl chr 7:27,969,789...28,001,600 		JBrowse link
G Magt1 magnesium transporter 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of MAGT1 protein CTD PMID:34122009 NCBI chr  X:71,038,489...71,079,704
Ensembl chr  X:71,038,489...71,079,699 		JBrowse link
G Mal mal, T-cell differentiation protein decreases expression ISO Clozapine results in decreased expression of MAL mRNA CTD PMID:17266109 PMID:18797397 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Maob monoamine oxidase B increases expression ISO Clozapine results in increased expression of MAOB mRNA CTD PMID:17266109 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Map1a microtubule-associated protein 1A increases expression
decreases expression		 EXP
ISO		 Clozapine results in increased expression of MAP1A mRNA
Clozapine results in decreased expression of MAP1A protein		 CTD PMID:15860345 PMID:34122009 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Map1b microtubule-associated protein 1B decreases expression ISO Clozapine results in decreased expression of MAP1B protein CTD PMID:34122009 NCBI chr 2:30,817,261...30,910,458
Ensembl chr 2:30,817,261...30,910,317 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases lipidation
multiple interactions		 ISO Clozapine results in increased lipidation of MAP1LC3B protein
[Chloroquine co-treated with Clozapine] results in increased lipidation of MAP1LC3B protein		 CTD PMID:36482696 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map1s microtubule-associated protein 1S increases expression ISO Clozapine results in increased expression of MAP1S protein CTD PMID:34122009 NCBI chr16:18,516,759...18,527,777
Ensembl chr16:18,517,574...18,527,988 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression EXP Clozapine results in decreased expression of MAP2K1 mRNA CTD PMID:15860345 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 increases expression
decreases expression		 ISO
EXP		 Clozapine results in increased expression of MAP2K2 mRNA
Clozapine results in decreased expression of MAP2K2 mRNA		 CTD PMID:14647396 PMID:15860345 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression EXP Clozapine results in decreased expression of MAP2K5 mRNA CTD PMID:15860345 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP Clozapine results in increased expression of MAP3K1 mRNA CTD PMID:15860345 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 increases expression EXP Clozapine results in increased expression of MAP3K12 mRNA CTD PMID:15860345 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases expression
decreases phosphorylation		 ISO
EXP		 Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]
Clozapine results in decreased expression of MAPK1 mRNA
Clozapine results in decreased phosphorylation of MAPK1 protein		 CTD PMID:12871586 PMID:15860345 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Clozapine affects the expression of MAPK14 mRNA CTD PMID:15860345 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions		 ISO Clozapine results in decreased phosphorylation of MAPK3 protein
Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:12871586 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk6 mitogen-activated protein kinase 6 affects expression EXP Clozapine affects the expression of MAPK6 mRNA CTD PMID:15860345 NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720 		JBrowse link
G Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 increases expression ISO Clozapine results in increased expression of MAPK8IP1 mRNA CTD PMID:17266109 NCBI chr 3:78,355,051...78,372,946
Ensembl chr 3:78,355,048...78,372,884 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 affects expression EXP Clozapine affects the expression of MAPK9 mRNA CTD PMID:15860345 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 decreases expression
multiple interactions		 ISO Clozapine results in decreased expression of MAPRE1 protein
[Cuprizone co-treated with Clozapine] results in decreased expression of MAPRE1 protein		 CTD PMID:34122009 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Clozapine results in decreased expression of MAS1 mRNA CTD PMID:16715494 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Mat2a methionine adenosyltransferase 2A decreases expression ISO Clozapine results in decreased expression of MAT2A protein CTD PMID:34122009 NCBI chr 4:104,489,877...104,495,447
Ensembl chr 4:104,488,466...104,495,493 		JBrowse link
G Mat2b methionine adenosyltransferase 2 non-catalytic beta subunit decreases expression ISO Clozapine results in decreased expression of MAT2B protein CTD PMID:34122009 NCBI chr10:25,106,928...25,122,982
Ensembl chr10:25,106,930...25,122,777 		JBrowse link
G Mbp myelin basic protein increases expression ISO Clozapine results in increased expression of MBP mRNA CTD PMID:17266109 PMID:17346280 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mc1r melanocortin 1 receptor increases expression ISO Clozapine results in increased expression of MC1R mRNA CTD PMID:17346280 NCBI chr19:51,452,448...51,455,375
Ensembl chr19:51,453,239...51,454,192 		JBrowse link
G Mdc1 mediator of DNA damage checkpoint 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of MDC1 protein CTD PMID:34122009 NCBI chr20:2,893,693...2,912,394
Ensembl chr20:2,895,505...2,910,240 		JBrowse link
G Mdh1 malate dehydrogenase 1 decreases expression ISO Clozapine results in decreased expression of MDH1 protein CTD PMID:34122009 NCBI chr14:95,630,625...95,645,920
Ensembl chr14:95,630,306...95,645,925 		JBrowse link
G Mfn2 mitofusin 2 decreases expression
multiple interactions		 EXP Clozapine results in decreased expression of MFN2 protein
PGRMC1 protein inhibits the reaction [Clozapine results in decreased expression of MFN2 protein]		 CTD PMID:37087062 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase increases expression ISO Clozapine results in increased expression of MLKL protein CTD PMID:31220554 NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502 		JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Clozapine results in decreased expression of MMP10 mRNA CTD PMID:17346280 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Clozapine results in increased expression of MMP14 protein CTD PMID:36482696 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp7 matrix metallopeptidase 7 decreases expression ISO Clozapine results in decreased expression of MMP7 mRNA CTD PMID:17346280 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mobp myelin-associated oligodendrocyte basic protein increases expression ISO Clozapine results in increased expression of MOBP mRNA CTD PMID:15542763 PMID:17266109 NCBI chr 8:119,869,504...119,899,605
Ensembl chr 8:119,869,626...119,899,563 		JBrowse link
G Mpo myeloperoxidase affects response to substance
increases activity
multiple interactions
increases oxidation		 ISO MPO protein affects the susceptibility to Clozapine
Clozapine results in increased activity of MPO protein
Clozapine promotes the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Clozapine promotes the reaction [MPO protein results in increased abundance of Hypochlorous Acid]
MPO protein results in increased oxidation of Clozapine		 CTD PMID:24588327 PMID:35575633 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mpp3 MAGUK p55 scaffold protein 3 decreases expression ISO Clozapine results in decreased expression of MPP3 mRNA CTD PMID:17266109 NCBI chr10:86,945,705...86,975,261
Ensembl chr10:86,945,714...86,974,737 		JBrowse link
G Mr1 major histocompatibility complex, class I-related affects expression ISO Clozapine affects the expression of MR1 mRNA CTD PMID:25811541 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Mta2 metastasis associated 1 family, member 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of MTA2 protein CTD PMID:34122009 NCBI chr 1:205,838,181...205,846,903
Ensembl chr 1:205,837,964...205,846,946 		JBrowse link
G Mtdh metadherin multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of MTDH protein CTD PMID:34122009 NCBI chr 7:65,306,464...65,365,647
Ensembl chr 7:65,306,400...65,364,413 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase affects response to substance ISO MTHFR gene polymorphism affects the susceptibility to Clozapine; MTHFR protein affects the susceptibility to Clozapine CTD PMID:20547447 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Myadm myeloid-associated differentiation marker multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of MYADM protein CTD PMID:34122009 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035 		JBrowse link
G Mybbp1a MYB binding protein 1a increases expression ISO Clozapine results in increased expression of MYBBP1A protein CTD PMID:34122009 NCBI chr10:57,056,897...57,067,258
Ensembl chr10:57,056,874...57,067,255 		JBrowse link
G Myh10 myosin heavy chain 10 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of MYH10 protein CTD PMID:34122009 NCBI chr10:53,393,901...53,525,174
Ensembl chr10:53,394,389...53,525,165 		JBrowse link
G Myh3 myosin heavy chain 3 increases expression ISO Clozapine results in increased expression of MYH3 protein CTD PMID:34122009 NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992 		JBrowse link
G Myl1 myosin, light chain 1 increases expression ISO Clozapine results in increased expression of MYL1 protein CTD PMID:34122009 NCBI chr 9:68,437,514...68,458,256
Ensembl chr 9:68,437,517...68,458,261 		JBrowse link
G Naa10 N(alpha)-acetyltransferase 10, NatA catalytic subunit decreases expression ISO Clozapine results in decreased expression of NAA10 protein CTD PMID:34122009 NCBI chr  X:151,656,056...151,661,304
Ensembl chr  X:151,656,056...151,661,252 		JBrowse link
G Nap1l4 nucleosome assembly protein 1-like 4 increases expression ISO Clozapine results in increased expression of NAP1L4 protein CTD PMID:34122009 NCBI chr 1:198,709,697...198,746,093
Ensembl chr 1:198,709,701...198,746,020 		JBrowse link
G Nat10 N-acetyltransferase 10 decreases expression ISO Clozapine results in decreased expression of NAT10 protein CTD PMID:34122009 NCBI chr 3:90,111,643...90,149,891
Ensembl chr 3:90,111,645...90,149,927 		JBrowse link
G Ncan neurocan decreases expression ISO Clozapine results in decreased expression of NCAN mRNA CTD PMID:18797397 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436 		JBrowse link
G Ncapg non-SMC condensin I complex, subunit G increases expression ISO Clozapine results in increased expression of NCAPG protein CTD PMID:34122009 NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO Clozapine results in decreased expression of NCAPH protein CTD PMID:34122009 PMID:36482696 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ncbp1 nuclear cap binding protein subunit 1 decreases expression ISO Clozapine results in decreased expression of NCBP1 protein CTD PMID:34122009 NCBI chr 5:60,416,023...60,449,004
Ensembl chr 5:60,415,982...60,449,089 		JBrowse link
G Ncl nucleolin increases expression ISO Clozapine results in increased expression of NCL mRNA CTD PMID:14647396 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136 		JBrowse link
G Ncoa4 nuclear receptor coactivator 4 increases expression ISO Clozapine results in increased expression of NCOA4 protein CTD PMID:36482696 NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 increases expression EXP Clozapine results in increased expression of NDUFV2 mRNA CTD PMID:19441803 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 decreases expression ISO Clozapine results in decreased expression of NECTIN2 protein CTD PMID:34122009 NCBI chr 1:79,372,123...79,407,379
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Clozapine results in decreased expression of NEDD4 mRNA CTD PMID:18797397 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Nes nestin decreases expression ISO Clozapine results in decreased expression of NES protein CTD PMID:34122009 NCBI chr 2:173,437,867...173,447,777
Ensembl chr 2:173,438,734...173,447,777 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects response to substance ISO NFE2L2 protein affects the susceptibility to Clozapine CTD PMID:21540358 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression EXP Clozapine results in decreased expression of NFKB1 protein CTD PMID:16500086 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Ngfr nerve growth factor receptor decreases expression ISO
EXP		 Clozapine results in decreased expression of NGFR protein; Clozapine results in decreased expression of NGFR protein alternative form
Clozapine results in decreased expression of NGFR mRNA		 CTD PMID:12111809 PMID:14598305 PMID:16513140 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 decreases expression ISO Clozapine results in decreased expression of NIFK protein CTD PMID:34122009 NCBI chr13:29,393,303...29,403,387
Ensembl chr13:29,393,286...29,405,896 		JBrowse link
G Nnmt nicotinamide N-methyltransferase increases expression ISO Clozapine results in increased expression of NNMT protein CTD PMID:34122009 NCBI chr 8:48,928,663...48,947,734
Ensembl chr 8:48,933,598...48,946,655 		JBrowse link
G Nnt nicotinamide nucleotide transhydrogenase decreases expression ISO Clozapine results in decreased expression of NNT protein CTD PMID:34122009 NCBI chr 2:51,411,413...51,505,125
Ensembl chr 2:51,411,413...51,504,823 		JBrowse link
G Noc2l NOC2-like nucleolar associated transcriptional repressor increases expression ISO Clozapine results in increased expression of NOC2L protein CTD PMID:34122009 NCBI chr 5:166,820,150...166,831,949
Ensembl chr 5:166,820,161...166,831,949 		JBrowse link
G Nomo1 Nodal modulator 1 increases expression ISO Clozapine results in increased expression of NOMO3 protein CTD PMID:34122009 NCBI chr 1:96,505,460...96,556,280
Ensembl chr 1:96,505,484...96,556,279 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor affects expression ISO Clozapine affects the expression of NOP53 mRNA CTD PMID:14647396 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Notch2 notch receptor 2 increases expression ISO Clozapine results in increased expression of NOTCH2 protein CTD PMID:36482696 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Nploc4 NPL4 homolog, ubiquitin recognition factor decreases expression ISO Clozapine results in decreased expression of NPLOC4 protein CTD PMID:34122009 NCBI chr10:105,654,395...105,709,958
Ensembl chr10:105,654,812...105,709,913 		JBrowse link
G Nptn neuroplastin increases expression ISO Clozapine results in increased expression of NPTN mRNA CTD PMID:18797397 NCBI chr 8:58,996,873...59,063,402
Ensembl chr 8:58,996,887...59,063,401 		JBrowse link
G Nptx2 neuronal pentraxin 2 decreases expression EXP Clozapine results in decreased expression of NPTX2 mRNA CTD PMID:18208916 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345 		JBrowse link
G Npy neuropeptide Y decreases expression EXP Clozapine results in decreased expression of NPY mRNA CTD PMID:16516965 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone dehydrogenase 2 affects response to substance
increases reduction
multiple interactions		 ISO NQO2 gene SNP affects the susceptibility to Clozapine
NQO2 protein results in increased reduction of Clozapine metabolite
Clozapine inhibits the reaction [NQO2 protein results in increased reduction of Vitamin K 3]		 CTD PMID:14617031 PMID:29281794 NCBI chr17:30,909,482...30,938,725
Ensembl chr17:30,909,187...30,938,320 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Clozapine results in increased expression of NR0B2 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO Clozapine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]; N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Clozapine promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]] CTD PMID:21402137 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Clozapine inhibits the reaction [Corticosterone results in increased activity of NR3C1 protein] CTD PMID:16581232 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 increases expression
decreases expression		 EXP Clozapine results in increased expression of NR4A1 mRNA
Clozapine results in decreased expression of NR4A1 mRNA		 CTD PMID:10987852 PMID:11564422 PMID:19695244 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Clozapine results in increased expression of NR4A2 mRNA CTD PMID:17266109 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nrg1 neuregulin 1 increases expression
affects expression
affects response to substance		 ISO
EXP		 Clozapine results in increased expression of NRG1 mRNA
Clozapine affects the expression of NRG1 protein
NRG1 protein affects the susceptibility to Clozapine		 CTD PMID:15706234 PMID:18184445 PMID:19502011 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression ISO Clozapine results in decreased expression of NSF protein CTD PMID:34122009 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Ntng2 netrin G2 increases expression EXP Clozapine results in increased expression of NTNG2 mRNA CTD PMID:17507910 NCBI chr 3:12,492,574...12,551,104
Ensembl chr 3:12,492,639...12,545,890 		JBrowse link
G Nts neurotensin increases expression EXP Clozapine results in increased expression of NTS mRNA CTD PMID:12887421 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Numa1 nuclear mitotic apparatus protein 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of NUMA1 protein CTD PMID:34122009 NCBI chr 1:156,297,907...156,372,855
Ensembl chr 1:156,326,259...156,372,855 		JBrowse link
G Numbl NUMB-like, endocytic adaptor protein decreases expression ISO Clozapine results in decreased expression of NUMBL mRNA CTD PMID:18797397 NCBI chr 1:82,549,814...82,573,788
Ensembl chr 1:82,550,054...82,573,776 		JBrowse link
G Nup160 nucleoporin 160 increases expression ISO Clozapine results in increased expression of NUP160 protein CTD PMID:34122009 NCBI chr 3:76,665,786...76,729,296
Ensembl chr 3:76,665,786...76,724,565 		JBrowse link
G Nup50 nucleoporin 50 increases expression ISO Clozapine results in increased expression of NUP50 protein CTD PMID:34122009 NCBI chr 7:116,047,960...116,065,231
Ensembl chr 7:116,048,021...116,066,905 		JBrowse link
G Nup54 nucleoporin 54 decreases expression ISO Clozapine results in decreased expression of NUP54 protein CTD PMID:34122009 NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Clozapine results in increased expression of NUPR1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Osbpl8 oxysterol binding protein-like 8 increases expression ISO Clozapine results in increased expression of OSBPL8 mRNA CTD PMID:14647396 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888 		JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide affects response to substance ISO OXT protein affects the susceptibility to Clozapine CTD PMID:20196918 NCBI chr 3:117,782,650...117,783,490
Ensembl chr 3:117,782,650...117,783,490 		JBrowse link
G Pakap paralemmin A kinase anchor protein multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of PALM2AKAP2 protein CTD PMID:34122009 NCBI chr 5:72,536,986...72,648,524
NCBI chr 5:72,313,646...72,450,645
Ensembl chr 5:72,181,718...72,648,524 		JBrowse link
G Pank3 pantothenate kinase 3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of PANK3 protein CTD PMID:34122009 NCBI chr10:20,229,129...20,252,955
Ensembl chr10:20,229,129...20,252,955 		JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Clozapine results in increased expression of PARK7 mRNA CTD PMID:14647396 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pcbp1 poly(rC) binding protein 1 increases expression ISO Clozapine results in increased expression of PCBP1 protein CTD PMID:34122009 NCBI chr 4:118,972,698...118,974,705
Ensembl chr 4:118,972,661...118,976,500 		JBrowse link
G Pck2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) decreases expression ISO Clozapine results in decreased expression of PCK2 protein CTD PMID:34122009 NCBI chr15:29,027,891...29,036,729
Ensembl chr15:29,027,894...29,037,283 		JBrowse link
G Pclo piccolo (presynaptic cytomatrix protein) multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of PCLO protein CTD PMID:34122009 NCBI chr 4:19,691,439...20,050,015
Ensembl chr 4:19,695,315...20,049,885 		JBrowse link
G Pcm1 pericentriolar material 1 decreases expression ISO Clozapine results in decreased expression of PCM1 mRNA CTD PMID:19048012 NCBI chr16:51,008,315...51,105,261
Ensembl chr16:51,008,315...51,105,091 		JBrowse link
G Pcnp PEST proteolytic signal containing nuclear protein increases expression ISO Clozapine results in increased expression of PCNP protein CTD PMID:34122009 NCBI chr11:44,592,766...44,607,372
Ensembl chr11:44,592,742...44,607,348 		JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor affects expression ISO Clozapine affects the expression of PCSK1N mRNA CTD PMID:14647396 NCBI chr  X:14,580,036...14,583,478
Ensembl chr  X:14,580,038...14,583,566 		JBrowse link
G Pdcd11 programmed cell death 11 increases expression ISO Clozapine results in increased expression of PDCD11 protein CTD PMID:34122009 NCBI chr 1:245,980,840...246,021,999
Ensembl chr 1:245,980,880...246,021,999 		JBrowse link
G Pde10a phosphodiesterase 10A increases expression ISO
EXP		 Clozapine results in increased expression of PDE10A mRNA
Clozapine results in increased expression of PDE10A mRNA; Clozapine results in increased expression of PDE10A protein		 CTD PMID:17266109 PMID:18222493 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563 		JBrowse link
G Pde1b phosphodiesterase 1B increases expression ISO Clozapine results in increased expression of PDE1B mRNA CTD PMID:14647396 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Pde4a phosphodiesterase 4A decreases expression EXP Clozapine results in decreased expression of PDE4A protein CTD PMID:20222156 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Pde4b phosphodiesterase 4B decreases expression
increases expression		 EXP Clozapine results in decreased expression of PDE4B protein
Clozapine results in increased expression of PDE4B mRNA; Clozapine results in increased expression of PDE4B protein		 CTD PMID:18222493 PMID:20222156 NCBI chr 5:116,799,819...117,369,155
Ensembl chr 5:116,799,971...117,367,696 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 decreases expression ISO Clozapine results in decreased expression of PDIA3 protein CTD PMID:34122009 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of PDIA4 protein CTD PMID:34122009 NCBI chr 4:76,803,198...76,822,245
Ensembl chr 4:76,803,198...76,822,107 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Clozapine results in decreased expression of PDLIM5 protein CTD PMID:34122009 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 decreases expression ISO Clozapine results in decreased expression of PEBP1 protein CTD PMID:34122009 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
G Penk proenkephalin decreases expression
increases expression		 EXP Clozapine results in decreased expression of PENK mRNA
Clozapine results in increased expression of PENK mRNA		 CTD PMID:1635659 PMID:12887421 NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pfdn5 prefoldin subunit 5 increases expression ISO Clozapine results in increased expression of PFDN5 mRNA CTD PMID:14647396 NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516 		JBrowse link
G Pfkp phosphofructokinase, platelet increases expression EXP Clozapine results in increased expression of PFKP mRNA CTD PMID:15860345 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Pgam5 PGAM family member 5, mitochondrial serine/threonine protein phosphatase decreases expression ISO Clozapine results in decreased expression of PGAM5 protein CTD PMID:34122009 NCBI chr12:46,409,324...46,416,410
Ensembl chr12:46,409,369...46,416,420 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression EXP Clozapine results in increased expression of PGK1 mRNA CTD PMID:15860345 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Pgrmc1 progesterone receptor membrane component 1 multiple interactions EXP PGRMC1 protein inhibits the reaction [Clozapine results in decreased expression of GLP1R protein]; PGRMC1 protein inhibits the reaction [Clozapine results in decreased expression of MFN2 protein] CTD PMID:37087062 NCBI chr  X:115,832,865...115,841,060
Ensembl chr  X:115,832,884...115,888,682 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 increases expression ISO Clozapine results in increased expression of PHACTR1 mRNA CTD PMID:14647396 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831 		JBrowse link
G Phf14 PHD finger protein 14 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of PHF14 protein CTD PMID:34122009 NCBI chr 4:40,009,691...40,195,877
Ensembl chr 4:40,009,264...40,195,885 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression EXP Clozapine results in decreased expression of PIK3R3 mRNA CTD PMID:16715494 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583 		JBrowse link
G Pitpnb phosphatidylinositol transfer protein, beta increases expression ISO Clozapine results in increased expression of PITPNB protein CTD PMID:34122009 NCBI chr12:45,249,308...45,298,388
Ensembl chr12:45,249,333...45,298,314 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression EXP Clozapine results in decreased expression of PKIB mRNA CTD PMID:15860345 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP Clozapine results in increased expression of PKM mRNA CTD PMID:15860345 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Plcb1 phospholipase C beta 1 increases expression ISO Clozapine results in increased expression of PLCB1 mRNA CTD PMID:16465460 NCBI chr 3:122,059,988...122,772,896
Ensembl chr 3:122,060,031...122,772,869 		JBrowse link
G Plp1 proteolipid protein 1 decreases expression
increases expression		 ISO Clozapine results in decreased expression of PLP1 mRNA
Clozapine results in increased expression of PLP1 mRNA		 CTD PMID:17266109 PMID:18797397 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Pls3 plastin 3 decreases expression ISO Clozapine results in decreased expression of PLS3 protein CTD PMID:34122009 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891 		JBrowse link
G Pnma1 PNMA family member 1 increases expression ISO Clozapine results in increased expression of PNMA1 protein CTD PMID:34122009 NCBI chr 6:103,782,244...103,784,029
Ensembl chr 6:103,773,889...103,784,567 		JBrowse link
G Pon3 paraoxonase 3 increases expression ISO Clozapine results in increased expression of PON3 protein CTD PMID:34122009 NCBI chr 4:33,356,983...33,383,681
Ensembl chr 4:33,349,168...33,383,855 		JBrowse link
G Ppa1 inorganic pyrophosphatase 1 increases expression ISO Clozapine results in increased expression of PPA1 protein CTD PMID:34122009 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases expression		 ISO Berberine inhibits the reaction [Clozapine results in increased expression of PPARG mRNA]; Berberine inhibits the reaction [Clozapine results in increased expression of PPARG protein]
Clozapine results in increased expression of PPARG mRNA; Clozapine results in increased expression of PPARG protein		 CTD PMID:20564506 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A decreases expression EXP Clozapine results in decreased expression of PPM1A mRNA CTD PMID:15860345 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression EXP Clozapine results in decreased expression of PPM1B mRNA CTD PMID:15860345 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression EXP Clozapine results in decreased expression of PPP1CB mRNA CTD PMID:15860345 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma decreases expression EXP Clozapine results in decreased expression of PPP1CC mRNA CTD PMID:15860345 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553 		JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B decreases expression ISO Clozapine results in decreased expression of PPP1R14B protein CTD PMID:34122009 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319 		JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A decreases expression EXP Clozapine results in decreased expression of PPP1R1A mRNA CTD PMID:15860345 NCBI chr 7:134,654,578...134,662,236
Ensembl chr 7:134,654,579...134,662,230 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B multiple interactions
increases phosphorylation		 ISO Clozapine inhibits the reaction [Serotonin results in decreased phosphorylation of PPP1R1B protein]; Clozapine inhibits the reaction [Serotonin results in increased phosphorylation of PPP1R1B protein]
Clozapine results in increased phosphorylation of PPP1R1B protein		 CTD PMID:11880652 PMID:12871586 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 decreases expression EXP Clozapine results in decreased expression of PPP1R2 mRNA CTD PMID:15860345 NCBI chr11:69,472,676...69,494,468
Ensembl chr11:69,472,555...69,494,463 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B increases expression EXP Clozapine results in increased expression of PPP1R9B protein CTD PMID:16844384 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha decreases expression EXP Clozapine results in decreased expression of PPP2CA mRNA CTD PMID:15860345 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP Clozapine results in decreased expression of PPP2CB mRNA CTD PMID:15860345 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression EXP Clozapine results in increased expression of PPP2R1A mRNA CTD PMID:15860345 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha decreases expression EXP Clozapine results in decreased expression of PPP2R2A mRNA CTD PMID:15860345 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions
increases expression
decreases expression		 EXP [Clozapine binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein
Clozapine results in increased expression of PPP3CA mRNA
Clozapine results in decreased expression of PPP3CA mRNA; Clozapine results in decreased expression of PPP3CA protein		 CTD PMID:12437575 PMID:16033416 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Ppp4r2 protein phosphatase 4, regulatory subunit 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of PPP4R2 protein CTD PMID:34122009 NCBI chr 4:133,454,555...133,495,486
Ensembl chr 4:133,454,555...133,495,486 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit affects expression ISO Clozapine affects the expression of PPP5C mRNA CTD PMID:14647396 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of PRDX1 protein CTD PMID:34122009 NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression EXP Clozapine results in increased expression of PRKACA mRNA CTD PMID:15860345 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta decreases expression
increases expression		 EXP Clozapine results in decreased expression of PRKACB mRNA; Clozapine results in decreased expression of PRKACB protein
Clozapine results in increased expression of PRKACB mRNA		 CTD PMID:11907174 PMID:15860345 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions
decreases expression		 EXP
ISO		 Clozapine inhibits the reaction [Cyclic AMP binds to PRKAR2A protein]
[Cuprizone co-treated with Clozapine] results in decreased expression of PRKAR2A protein
Clozapine results in decreased expression of PRKAR2A mRNA; Clozapine results in decreased expression of PRKAR2A protein		 CTD PMID:11907174 PMID:34122009 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta decreases expression
multiple interactions		 EXP Clozapine results in decreased expression of PRKAR2B mRNA; Clozapine results in decreased expression of PRKAR2B protein
Clozapine inhibits the reaction [Cyclic AMP binds to PRKAR2B protein]		 CTD PMID:11907174 PMID:15860345 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933 		JBrowse link
G Prkcb protein kinase C, beta affects expression
increases expression		 EXP Clozapine affects the expression of PRKCB protein
Clozapine results in increased expression of PRKCB mRNA		 CTD PMID:15860345 PMID:15967061 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkce protein kinase C, epsilon increases expression EXP Clozapine results in increased expression of PRKCE mRNA CTD PMID:15860345 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP Clozapine results in increased expression of PRKCZ mRNA CTD PMID:15860345 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Prl prolactin increases secretion
increases expression
multiple interactions		 ISO
EXP		 Clozapine results in increased secretion of PRL protein
Clozapine analog results in increased expression of PRL protein
[Clozapine co-treated with DRD2 gene polymorphism] results in increased secretion of PRL protein; [Risperidone co-treated with Clozapine] results in increased expression of PRL protein		 CTD PMID:11155212 PMID:11997696 PMID:15286066 PMID:18562423 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prmt1 protein arginine methyltransferase 1 decreases expression ISO Clozapine results in decreased expression of PRMT1 protein CTD PMID:34122009 NCBI chr 1:95,458,853...95,468,176
Ensembl chr 1:95,458,850...95,468,345 		JBrowse link
G Proc protein C, inactivator of coagulation factors Va and VIIIa increases expression ISO Clozapine results in increased expression of PROC protein CTD PMID:20126316 NCBI chr18:23,764,367...23,774,816
Ensembl chr18:23,764,368...23,775,133 		JBrowse link
G Prpf38b pre-mRNA processing factor 38B decreases expression ISO Clozapine results in decreased expression of PRPF38B mRNA CTD PMID:14647396 NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250 		JBrowse link
G Prpf6 pre-mRNA processing factor 6 decreases expression
multiple interactions		 ISO Clozapine results in decreased expression of PRPF6 protein
[Cuprizone co-treated with Clozapine] results in decreased expression of PRPF6 protein		 CTD PMID:34122009 NCBI chr 3:168,706,952...168,771,191
Ensembl chr 3:168,704,299...168,774,991 		JBrowse link
G Prrc2a proline-rich coiled-coil 2A decreases expression ISO Clozapine results in decreased expression of PRRC2A mRNA CTD PMID:18797397 NCBI chr20:3,658,391...3,674,143
Ensembl chr20:3,658,695...3,674,130 		JBrowse link
G Psmb5 proteasome 20S subunit beta 5 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of PSMB5 protein CTD PMID:34122009 NCBI chr15:28,072,772...28,077,367
Ensembl chr15:28,072,781...28,077,440 		JBrowse link
G Psmb7 proteasome 20S subunit beta 7 decreases expression ISO Clozapine results in decreased expression of PSMB7 protein CTD PMID:34122009 NCBI chr 3:22,357,777...22,417,748
Ensembl chr 3:22,354,698...22,417,937 		JBrowse link
G Psmc3 proteasome 26S subunit, ATPase 3 increases expression ISO Clozapine results in increased expression of PSMC3 protein CTD PMID:34122009 NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358 		JBrowse link
G Psmc5 proteasome 26S subunit, ATPase 5 increases expression ISO Clozapine results in increased expression of PSMC5 protein CTD PMID:34122009 NCBI chr10:91,187,763...91,193,697
Ensembl chr10:91,187,743...91,213,135 		JBrowse link
G Psmd14 proteasome 26S subunit, non-ATPase 14 increases expression ISO Clozapine results in increased expression of PSMD14 protein CTD PMID:34122009 NCBI chr 3:46,254,338...46,347,076
Ensembl chr 3:46,254,330...46,347,076 		JBrowse link
G Psmd7 proteasome 26S subunit, non-ATPase 7 increases expression ISO Clozapine results in increased expression of PSMD7 protein CTD PMID:34122009 NCBI chr19:35,494,317...35,501,605
Ensembl chr19:35,494,316...35,501,588 		JBrowse link
G Ptcd3 Pentatricopeptide repeat domain 3 increases expression ISO Clozapine results in increased expression of PTCD3 protein CTD PMID:34122009 NCBI chr 4:103,922,440...103,957,445
Ensembl chr 4:103,920,566...103,957,538 		JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression
increases expression		 ISO Clozapine results in decreased expression of PTGDS mRNA
Clozapine results in increased expression of PTGDS mRNA		 CTD PMID:15542763 PMID:17266109 NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833 		JBrowse link
G Ptk2 protein tyrosine kinase 2 increases expression ISO Clozapine results in increased expression of PTK2 protein CTD PMID:34122009 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Ptma prothymosin alpha increases expression ISO Clozapine results in increased expression of PTMA protein CTD PMID:34122009 NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333 		JBrowse link
G Ptms parathymosin increases expression ISO Clozapine results in increased expression of PTMS mRNA CTD PMID:14647396 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009 		JBrowse link
G Pvalb parvalbumin multiple interactions EXP Clozapine inhibits the reaction [Phencyclidine results in decreased expression of PVALB mRNA] CTD PMID:12589379 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561 		JBrowse link
G Pwp2 PWP2, small subunit processome component increases expression ISO Clozapine results in increased expression of PWP2 protein CTD PMID:34122009 NCBI chr20:10,499,332...10,512,965
Ensembl chr20:10,499,363...10,513,640 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 increases expression ISO Clozapine results in increased expression of PYCR1 protein CTD PMID:34122009 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Qdpr quinoid dihydropteridine reductase decreases expression ISO Clozapine results in decreased expression of QDPR protein CTD PMID:34122009 NCBI chr14:65,670,251...65,683,853
Ensembl chr14:65,670,131...65,683,854 		JBrowse link
G Rab12 RAB12, member RAS oncogene family decreases expression EXP Clozapine results in decreased expression of RAB12 mRNA CTD PMID:12437575 NCBI chr 9:106,480,301...106,506,895
Ensembl chr 9:106,480,301...106,506,910 		JBrowse link
G Rac1 Rac family small GTPase 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of RAC1 protein CTD PMID:34122009 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rack1 receptor for activated C kinase 1 decreases expression ISO Clozapine results in decreased expression of RACK1 protein CTD PMID:34122009 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Ralyl RALY RNA binding protein-like increases expression ISO Clozapine results in increased expression of RALYL protein CTD PMID:34122009 NCBI chr 2:87,482,747...88,274,329
Ensembl chr 2:87,482,755...88,274,452 		JBrowse link
G Ran RAN, member RAS oncogene family decreases expression ISO Clozapine results in decreased expression of RAN protein CTD PMID:34122009 NCBI chr12:27,674,049...27,678,598
Ensembl chr12:27,674,050...27,678,276 		JBrowse link
G Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 increases expression ISO Clozapine results in increased expression of RAP1GDS1 protein CTD PMID:34122009 NCBI chr 2:227,500,366...227,645,213
Ensembl chr 2:227,500,367...227,645,169 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO Clozapine results in decreased expression of RAPGEF4 mRNA CTD PMID:18797397 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects expression EXP Clozapine affects the expression of RASGRF1 mRNA CTD PMID:12437575 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rbbp4 RB binding protein 4, chromatin remodeling factor decreases expression ISO Clozapine results in decreased expression of RBBP4 protein CTD PMID:34122009 NCBI chr 5:141,655,863...141,675,157
Ensembl chr 5:141,638,421...141,675,284 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases expression EXP Clozapine results in decreased expression of RELA protein CTD PMID:16500086 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Reln reelin decreases expression
multiple interactions
decreases methylation		 ISO
EXP		 Clozapine results in decreased expression of RELN mRNA
Clozapine results in decreased expression of RELN protein
Valproic Acid promotes the reaction [Clozapine results in decreased methylation of RELN promoter]		 CTD PMID:17266109 PMID:18757738 PMID:19359144 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rfc5 replication factor C subunit 5 increases expression ISO Clozapine results in increased expression of RFC5 protein CTD PMID:34122009 NCBI chr12:39,207,484...39,217,041
Ensembl chr12:39,207,484...39,217,312 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression EXP
ISO		 Clozapine results in increased expression of RGS4 mRNA CTD PMID:15860345 PMID:17266109 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 multiple interactions
increases expression		 EXP [[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein; alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [[[Clozapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein]
Clozapine results in increased expression of RGS7 mRNA		 CTD PMID:18976543 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 increases expression EXP Clozapine results in increased expression of RGS8 mRNA CTD PMID:15860345 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Rhob ras homolog family member B increases expression ISO Clozapine results in increased expression of RHOB protein CTD PMID:36482696 NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108 		JBrowse link
G Ric8a RIC8 guanine nucleotide exchange factor A decreases expression ISO Clozapine results in decreased expression of RIC8A protein CTD PMID:34122009 NCBI chr 1:195,935,162...195,941,469
Ensembl chr 1:195,935,349...195,941,467 		JBrowse link
G Rnf13 ring finger protein 13 increases expression ISO Clozapine results in increased expression of RNF13 protein CTD PMID:36482696 NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801 		JBrowse link
G Rnf20 ring finger protein 20 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of RNF20 protein CTD PMID:34122009 NCBI chr 5:63,976,063...64,001,754
Ensembl chr 5:63,976,045...64,001,754 		JBrowse link
G Rorb RAR-related orphan receptor B decreases expression EXP Clozapine results in decreased expression of RORB mRNA CTD PMID:11564422 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390 		JBrowse link
G Rpa1 replication protein A1 decreases expression ISO Clozapine results in decreased expression of RPA1 protein CTD PMID:34122009 NCBI chr10:60,148,869...60,199,970
Ensembl chr10:60,148,793...60,199,949 		JBrowse link
G Rpl11 ribosomal protein L11 increases expression ISO Clozapine results in increased expression of RPL11 protein CTD PMID:34122009 NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599 		JBrowse link
G Rpl19 ribosomal protein L19 increases expression ISO Clozapine results in increased expression of RPL19 protein CTD PMID:34122009 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112 		JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO Clozapine results in increased expression of RPL30 protein CTD PMID:34122009 NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363 		JBrowse link
G Rpl5 ribosomal protein L5 increases expression ISO Clozapine results in increased expression of RPL5 protein CTD PMID:34122009 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290 		JBrowse link
G Rplp0l1 ribosomal protein lateral stalk subunit P0 like 1 decreases expression ISO Clozapine results in decreased expression of RPLP0P6 protein CTD PMID:34122009 NCBI chr 2:191,921,503...191,922,661
Ensembl chr 2:191,921,574...191,922,646 		JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 increases expression ISO Clozapine results in increased expression of RPLP2 mRNA CTD PMID:14647396 NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645 		JBrowse link
G Rpn2 ribophorin II decreases expression ISO Clozapine results in decreased expression of RPN2 protein CTD PMID:34122009 NCBI chr 3:145,941,787...145,989,271
Ensembl chr 3:145,941,839...145,989,543 		JBrowse link
G Rps10 ribosomal protein S10 increases expression ISO Clozapine results in increased expression of RPS10 mRNA CTD PMID:14647396 NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044
Ensembl chr 6:5,694,313...5,699,044 		JBrowse link
G Rps11 ribosomal protein S11 decreases expression ISO Clozapine results in decreased expression of RPS11 protein CTD PMID:34122009 NCBI chr 1:95,605,690...95,607,798
Ensembl chr 1:95,605,692...95,607,874 		JBrowse link
G Rps3 ribosomal protein S3 decreases expression ISO Clozapine results in decreased expression of RPS3 protein CTD PMID:34122009 NCBI chr 1:153,778,363...153,783,663
Ensembl chr 1:153,777,472...153,783,680 		JBrowse link
G Rrbp1 ribosome binding protein 1 decreases expression ISO Clozapine results in decreased expression of RRBP1 protein CTD PMID:34122009 NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981 		JBrowse link
G Rsf1 remodeling and spacing factor 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of RSF1 protein CTD PMID:34122009 NCBI chr 1:151,892,055...152,015,089
Ensembl chr 1:151,892,434...152,009,051 		JBrowse link
G Rspry1 ring finger and SPRY domain containing 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of RSPRY1 protein CTD PMID:34122009 NCBI chr19:10,352,449...10,403,015
Ensembl chr19:10,353,821...10,401,102 		JBrowse link
G RT1-A2 RT1 class Ia, locus A2 increases expression ISO Clozapine results in increased expression of HLA-E protein CTD PMID:36482696 NCBI chr20:4,870,939...4,910,183 JBrowse link
G Rtcb RNA 2',3'-cyclic phosphate and 5'-OH ligase increases expression ISO Clozapine results in increased expression of RTCB protein CTD PMID:34122009 NCBI chr 7:17,907,668...17,927,136
Ensembl chr 7:17,907,705...17,927,132 		JBrowse link
G Rtn4 reticulon 4 increases expression ISO Clozapine results in increased expression of RTN4 mRNA CTD PMID:17266109 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Rxrg retinoid X receptor gamma decreases expression EXP Clozapine results in decreased expression of RXRG mRNA alternative form CTD PMID:11564422 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Clozapine results in decreased expression of S100A9 mRNA CTD PMID:18797397 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Safb scaffold attachment factor B increases expression ISO Clozapine results in increased expression of SAFB protein CTD PMID:34122009 NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Clozapine results in decreased expression of SARS1 protein CTD PMID:34122009 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277 		JBrowse link
G Satb2 SATB homeobox 2 increases expression ISO Clozapine results in increased expression of SATB2 protein CTD PMID:34122009 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Clozapine results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Clozapine results in increased expression of SCD mRNA CTD PMID:16027736 PMID:17052361 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sdcbp syndecan binding protein decreases expression
increases expression		 ISO Clozapine results in decreased expression of SDCBP protein
Clozapine results in increased expression of SDCBP protein		 CTD PMID:34122009 PMID:36482696 NCBI chr 5:19,473,499...19,517,188
Ensembl chr 5:19,489,961...19,527,572 		JBrowse link
G Sec31a SEC31 homolog A, COPII coat complex component increases expression ISO Clozapine results in increased expression of SEC31A protein CTD PMID:34122009 NCBI chr14:9,214,324...9,269,281
Ensembl chr14:9,214,349...9,269,273 		JBrowse link
G Sec61b SEC61 translocon subunit beta increases expression ISO Clozapine results in increased expression of SEC61B protein CTD PMID:34122009 NCBI chr 5:61,773,594...61,781,804
Ensembl chr 5:61,773,594...61,781,804 		JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression ISO Clozapine results in increased expression of SEC63 protein CTD PMID:34122009 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055 		JBrowse link
G Septin14 septin 14 decreases expression ISO Clozapine results in decreased expression of SEPTIN14 protein CTD PMID:34122009 NCBI chr12:26,975,283...27,005,588
Ensembl chr12:26,975,344...26,998,299 		JBrowse link
G Serinc1 serine incorporator 1 increases expression ISO Clozapine results in increased expression of SERINC1 protein CTD PMID:36482696 NCBI chr20:36,850,062...36,868,999
Ensembl chr20:36,850,076...36,896,691 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N increases expression ISO Clozapine results in increased expression of SERPINA3 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpine2 serpin family E member 2 increases expression EXP Clozapine results in increased expression of SERPINE2 mRNA; Clozapine results in increased expression of SERPINE2 protein CTD PMID:15354176 NCBI chr 9:81,124,746...81,188,866
Ensembl chr 9:81,124,804...81,188,826 		JBrowse link
G Set Set nuclear proto-oncogene multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of SET protein CTD PMID:34122009 NCBI chr 3:13,334,564...13,345,598
Ensembl chr 3:13,335,041...13,363,567 		JBrowse link
G Setx senataxin increases expression ISO Clozapine results in increased expression of SETX protein CTD PMID:34122009 NCBI chr 3:12,428,091...12,480,801
Ensembl chr 3:12,427,635...12,480,803 		JBrowse link
G Sf3b3 splicing factor 3b, subunit 3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of SF3B3 protein CTD PMID:34122009 NCBI chr19:38,782,749...38,820,271
Ensembl chr19:38,783,040...38,820,245 		JBrowse link
G Sfpq splicing factor proline and glutamine rich decreases expression ISO Clozapine results in decreased expression of SFPQ protein CTD PMID:34122009 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472 		JBrowse link
G Sfxn1 sideroflexin 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of SFXN1 protein CTD PMID:34122009 NCBI chr17:10,486,250...10,522,640
Ensembl chr17:10,486,271...10,522,529 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO
EXP		 Clozapine results in increased expression of SGK1 mRNA CTD PMID:17266109 PMID:18208916 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sh3gl1 SH3 domain containing GRB2 like 1, endophilin A2 increases expression ISO Clozapine results in increased expression of SH3GL1 protein CTD PMID:34122009 NCBI chr 9:842,285...869,753
Ensembl chr 9:842,288...869,716 		JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 increases expression ISO Clozapine results in increased expression of SH3KBP1 protein CTD PMID:34122009 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of SH3PXD2B protein CTD PMID:34122009 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170 		JBrowse link
G Sim2 SIM bHLH transcription factor 2 decreases expression ISO Clozapine results in decreased expression of SIM2 protein CTD PMID:34122009 NCBI chr11:33,414,218...33,453,663
Ensembl chr11:33,414,218...33,453,663 		JBrowse link
G Sirt2 sirtuin 2 increases expression ISO Clozapine results in increased expression of SIRT2 protein CTD PMID:36482696 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Skp1 S-phase kinase-associated protein 1 decreases expression ISO Clozapine results in decreased expression of SKP1 protein CTD PMID:34122009 NCBI chr10:36,401,987...36,417,066
Ensembl chr10:36,402,153...36,417,388 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Clozapine results in increased expression of SLC17A6 mRNA; Clozapine results in increased expression of SLC17A6 protein CTD PMID:17266109 PMID:18155072 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Slc17a7 solute carrier family 17 member 7 increases expression ISO Clozapine results in increased expression of SLC17A7 mRNA; Clozapine results in increased expression of SLC17A7 protein CTD PMID:16111724 NCBI chr 1:95,649,709...95,661,591
Ensembl chr 1:95,649,745...95,661,588 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 increases expression EXP Clozapine results in increased expression of SLC18A2 mRNA; Clozapine results in increased expression of SLC18A2 protein CTD PMID:12007678 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression EXP Clozapine results in decreased expression of SLC1A1 mRNA CTD PMID:12873733 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases activity
decreases expression		 EXP Clozapine results in decreased activity of SLC1A2 protein
Clozapine results in decreased expression of SLC1A2 mRNA; Clozapine results in decreased expression of SLC1A2 protein		 CTD PMID:11443521 PMID:12873733 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Clozapine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Clozapine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] CTD PMID:30465787 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Slc25a13 solute carrier family 25 member 13 increases expression ISO Clozapine results in increased expression of SLC25A13 protein CTD PMID:34122009 NCBI chr 4:34,179,224...34,361,912
Ensembl chr 4:34,179,224...34,361,902 		JBrowse link
G Slc25a24 solute carrier family 25 member 24 increases expression ISO Clozapine results in increased expression of SLC25A24 protein CTD PMID:34122009 NCBI chr 2:196,761,076...196,799,236
Ensembl chr 2:196,761,274...196,799,231 		JBrowse link
G Slc25a6 solute carrier family 25 member 6 increases expression ISO Clozapine results in increased expression of SLC25A6 protein CTD PMID:34122009 NCBI chr18:68,571,222...68,572,461
Ensembl chr18:68,571,300...68,572,199 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Clozapine results in decreased expression of SLC2A3 mRNA CTD PMID:15342952 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc39a7 solute carrier family 39 member 7 increases expression ISO Clozapine results in increased expression of SLC39A7 mRNA CTD PMID:14647396 NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Clozapine results in increased expression of SLC3A2 protein CTD PMID:36482696 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 decreases expression EXP Clozapine results in decreased expression of SLC6A2 mRNA CTD PMID:18923069 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 affects response to substance ISO SLC6A3 5' UTR affects the susceptibility to Clozapine CTD PMID:20580759 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions
increases expression
affects response to substance		 ISO
EXP		 [SLC6A4 gene polymorphism results in decreased uptake of Serotonin] which results in decreased susceptibility to Clozapine
Clozapine results in increased expression of SLC6A4
SLC6A4 protein affects the susceptibility to Clozapine		 CTD PMID:12007678 PMID:20452607 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Smarcb1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 decreases expression ISO Clozapine results in decreased expression of SMARCB1 protein CTD PMID:34122009 NCBI chr20:12,741,164...12,763,616
Ensembl chr20:12,741,477...12,763,620 		JBrowse link
G Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of SMARCC2 protein CTD PMID:34122009 NCBI chr 7:881,844...910,090
Ensembl chr 7:881,421...909,978 		JBrowse link
G Smc2 structural maintenance of chromosomes 2 decreases expression ISO Clozapine results in decreased expression of SMC2 protein CTD PMID:34122009 NCBI chr 5:66,806,882...66,853,478
Ensembl chr 5:66,807,011...66,853,242 		JBrowse link
G Smc3 structural maintenance of chromosomes 3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of SMC3 protein CTD PMID:34122009 NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522 		JBrowse link
G Snap25 synaptosome associated protein 25 increases expression
affects response to substance		 EXP
ISO		 Clozapine results in increased expression of SNAP25 mRNA
SNAP25 gene SNP affects the susceptibility to Clozapine		 CTD PMID:15823421 PMID:15860345 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Snrnp200 small nuclear ribonucleoprotein U5 subunit 200 increases expression ISO Clozapine results in increased expression of SNRNP200 protein CTD PMID:34122009 NCBI chr 3:114,428,854...114,458,194
Ensembl chr 3:114,428,854...114,458,182 		JBrowse link
G Snrpb small nuclear ribonucleoprotein polypeptides B and B1 increases expression ISO Clozapine results in increased expression of SNRPB protein CTD PMID:34122009 NCBI chr 3:117,369,816...117,379,344
Ensembl chr 3:117,370,100...117,379,339 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide increases expression ISO Clozapine results in increased expression of SNRPD2 mRNA CTD PMID:14647396 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351 		JBrowse link
G Snx1 sorting nexin 1 decreases expression ISO Clozapine results in decreased expression of SNX1 protein CTD PMID:34122009 NCBI chr 8:66,630,086...66,670,418
Ensembl chr 8:66,630,086...66,670,360 		JBrowse link
G Snx6 sorting nexin 6 increases expression ISO Clozapine results in increased expression of SNX6 protein CTD PMID:34122009 NCBI chr 6:72,230,950...72,274,157
Ensembl chr 6:72,229,870...72,315,911 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions		 EXP
ISO		 Clozapine results in increased expression of SOD1 mRNA
Clozapine results in decreased expression of SOD1 protein
Clozapine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SOD1 mRNA]; Clozapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]		 CTD PMID:12111809 PMID:12752374 PMID:16564057 PMID:34122009 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression EXP Clozapine results in decreased expression of SOD2 mRNA CTD PMID:15860345 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Clozapine results in increased expression of SOD3 mRNA CTD PMID:15860345 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 decreases expression
increases expression		 EXP Clozapine results in decreased expression of SOS1 mRNA
Clozapine results in increased expression of SOS1 mRNA		 CTD PMID:12437575 NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107 		JBrowse link
G Spp1 secreted phosphoprotein 1 decreases expression ISO Clozapine results in decreased expression of SPP1 mRNA CTD PMID:17346280 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sptlc1 serine palmitoyltransferase, long chain base subunit 1 decreases expression ISO Clozapine results in decreased expression of SPTLC1 protein CTD PMID:34122009 NCBI chr17:11,877,249...11,916,295
Ensembl chr17:11,877,249...11,916,295 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Clozapine results in increased expression of SQSTM1 protein CTD PMID:36482696 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression
multiple interactions		 ISO Clozapine results in increased expression of SREBF1 mRNA
Clozapine results in increased expression of SREBF1 mRNA; Clozapine results in increased expression of SREBF1 protein
Berberine inhibits the reaction [Clozapine results in increased expression of SREBF1 mRNA]; Berberine inhibits the reaction [Clozapine results in increased expression of SREBF1 protein]		 CTD PMID:17052361 PMID:19682446 PMID:20564506 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions
increases expression		 ISO Clozapine inhibits the reaction [25-hydroxycholesterol results in decreased activity of SREBF2 protein]; Clozapine results in increased cleavage of and results in increased activity of SREBF2 protein
Clozapine results in increased expression of SREBF2 mRNA		 CTD PMID:17052361 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Srrm2 serine/arginine repetitive matrix 2 decreases expression ISO Clozapine results in decreased expression of SRRM2 protein CTD PMID:34122009 NCBI chr10:12,815,471...12,848,750
Ensembl chr10:12,815,471...12,848,751 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of SRSF2 protein CTD PMID:34122009 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Clozapine] results in increased expression of SRSF5 protein
Clozapine results in increased expression of SRSF5 protein		 CTD PMID:34122009 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Srsf7 serine and arginine rich splicing factor 7 decreases expression ISO Clozapine results in decreased expression of SRSF7 protein CTD PMID:34122009 NCBI chr 6:14,811,775...14,818,968
Ensembl chr 6:14,811,808...14,818,965 		JBrowse link
G Ssr3 signal sequence receptor subunit 3 decreases expression ISO Clozapine results in decreased expression of SSR3 protein CTD PMID:34122009 NCBI chr 2:149,605,005...149,625,069
Ensembl chr 2:149,605,005...149,625,132 		JBrowse link
G Sst somatostatin multiple interactions EXP Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of SST mRNA]; Clozapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of SST protein] CTD PMID:16567023 NCBI chr11:76,956,896...76,958,173
Ensembl chr11:76,956,896...76,958,173 		JBrowse link
G Stim1 stromal interaction molecule 1 decreases expression ISO Clozapine results in decreased expression of STIM1 protein CTD PMID:34122009 NCBI chr 1:156,656,246...156,818,777
Ensembl chr 1:156,656,013...156,818,363 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Clozapine results in decreased expression of STIP1 protein CTD PMID:34122009 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Strap serine/threonine kinase receptor associated protein decreases expression ISO Clozapine results in decreased expression of STRAP protein CTD PMID:34122009 NCBI chr 4:170,646,042...170,660,291
Ensembl chr 4:170,646,001...170,660,828 		JBrowse link
G Strn4 striatin 4 increases expression ISO Clozapine results in increased expression of STRN4 mRNA CTD PMID:14647396 NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858 		JBrowse link
G Stx1a syntaxin 1A increases expression EXP Clozapine results in increased expression of STX1A mRNA CTD PMID:15860345 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930 		JBrowse link
G Stx1b syntaxin 1B increases expression EXP Clozapine results in increased expression of STX1B mRNA CTD PMID:15860345 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
G Stx4 syntaxin 4 increases expression EXP Clozapine results in increased expression of STX4 mRNA CTD PMID:15860345 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Stx8 syntaxin 8 affects expression EXP Clozapine affects the expression of STX8 mRNA CTD PMID:15860345 NCBI chr10:52,655,643...52,900,048
Ensembl chr10:52,654,990...52,894,993 		JBrowse link
G Stxbp1 syntaxin binding protein 1 affects expression EXP Clozapine affects the expression of STXBP1 mRNA CTD PMID:12437575 NCBI chr 3:16,076,725...16,138,431
Ensembl chr 3:16,076,391...16,138,369 		JBrowse link
G Sucla2 succinate-CoA ligase ADP-forming subunit beta multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of SUCLA2 protein CTD PMID:34122009 NCBI chr15:48,752,356...48,805,495
Ensembl chr15:48,752,312...48,805,138 		JBrowse link
G Suclg1 succinate-CoA ligase GDP/ADP-forming subunit alpha decreases expression ISO Clozapine results in decreased expression of SUCLG1 protein CTD PMID:34122009 NCBI chr 4:105,308,236...105,337,595
Ensembl chr 4:105,308,039...105,337,600 		JBrowse link
G Supt3h SPT3 homolog, SAGA and STAGA complex component increases expression EXP Clozapine results in increased expression of SUPT3H mRNA CTD PMID:16715494 NCBI chr 9:15,878,296...16,206,768
Ensembl chr 9:15,868,287...16,206,706 		JBrowse link
G Syn2 synapsin II decreases expression
increases expression		 ISO
EXP		 Clozapine results in decreased expression of SYN2 mRNA
Clozapine results in increased expression of SYN2 mRNA		 CTD PMID:15860345 PMID:17266109 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192 		JBrowse link
G Syncrip synaptotagmin binding, cytoplasmic RNA interacting protein decreases expression ISO Clozapine results in decreased expression of SYNCRIP protein CTD PMID:34122009 NCBI chr 8:89,402,487...89,435,517
Ensembl chr 8:89,402,866...89,435,515 		JBrowse link
G Syt11 synaptotagmin 11 increases expression EXP Clozapine results in increased expression of SYT11 mRNA CTD PMID:15860345 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964 		JBrowse link
G Syt2 synaptotagmin 2 increases expression ISO Clozapine results in increased expression of SYT2 mRNA CTD PMID:17266109 NCBI chr13:46,088,046...46,197,976
Ensembl chr13:46,185,282...46,193,859 		JBrowse link
G Syt4 synaptotagmin 4 increases expression EXP Clozapine results in increased expression of SYT4 mRNA CTD PMID:15860345 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
G Syt5 synaptotagmin 5 decreases expression EXP Clozapine results in decreased expression of SYT5 mRNA CTD PMID:12437575 NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067 		JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression ISO
EXP		 Clozapine results in decreased expression of TAC1 mRNA CTD PMID:10974607 PMID:17266109 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tagln transgelin decreases expression ISO Clozapine results in decreased expression of TAGLN mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tagln2 transgelin 2 decreases expression ISO Clozapine results in decreased expression of TAGLN2 protein CTD PMID:34122009 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972 		JBrowse link
G Taok2 TAO kinase 2 increases expression ISO Clozapine results in increased expression of TAOK2 protein CTD PMID:34122009 NCBI chr 1:181,475,708...181,494,738
Ensembl chr 1:181,475,711...181,494,613 		JBrowse link
G Tatdn1 TatD DNase domain containing 1 increases expression ISO Clozapine results in increased expression of TATDN1 mRNA CTD PMID:14647396 NCBI chr 7:90,449,979...90,481,000
Ensembl chr 7:90,441,079...90,481,133 		JBrowse link
G Tbc1d15 TBC1 domain family, member 15 increases expression ISO Clozapine results in increased expression of TBC1D15 protein CTD PMID:36482696 NCBI chr 7:50,804,553...50,860,272
Ensembl chr 7:50,804,012...50,860,175 		JBrowse link
G Tbc1d8b TBC1 domain family member 8B increases expression ISO Clozapine results in increased expression of TBC1D8B protein CTD PMID:34122009 NCBI chr  X:103,319,181...103,407,137
Ensembl chr  X:103,319,340...103,407,133 		JBrowse link
G Tbcb tubulin folding cofactor B multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of TBCB protein CTD PMID:34122009 NCBI chr 1:85,477,639...85,483,488
Ensembl chr 1:85,477,640...85,483,488 		JBrowse link
G Tbl3 transducin (beta)-like 3 increases expression ISO Clozapine results in increased expression of TBL3 protein CTD PMID:34122009 NCBI chr10:13,726,127...13,731,340
Ensembl chr10:13,726,129...13,731,372 		JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 decreases expression ISO Clozapine results in decreased expression of TCAF1 protein CTD PMID:34122009 NCBI chr 4:71,589,674...71,639,274
Ensembl chr 4:71,591,200...71,613,309 		JBrowse link
G Tes testin LIM domain protein decreases expression ISO Clozapine results in decreased expression of TES protein CTD PMID:34122009 NCBI chr 4:45,365,304...45,403,829
Ensembl chr 4:45,365,285...45,403,829 		JBrowse link
G Tgoln2 trans-golgi network protein 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of TGOLN2 protein CTD PMID:34122009 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164 		JBrowse link
G Th tyrosine hydroxylase decreases activity
multiple interactions
increases expression
decreases expression
increases activity		 EXP
ISO		 Clozapine results in decreased activity of TH protein
Ethylmaleimide inhibits the reaction [Clozapine results in decreased expression of TH protein]
Clozapine results in increased expression of TH protein
Clozapine results in decreased expression of TH mRNA; Clozapine results in decreased expression of TH protein
Clozapine results in increased activity of TH protein
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine promotes the reaction [[Clozapine results in increased activity of TH protein] which results in increased metabolism of Dopamine]; [Clozapine results in increased activity of TH protein] which results in increased metabolism of Dopamine		 CTD PMID:12645084 PMID:15983997 PMID:16402076 PMID:16415089 PMID:17028028 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thra thyroid hormone receptor alpha decreases expression
increases expression		 EXP Clozapine results in decreased expression of THRA mRNA alternative form
Clozapine results in increased expression of THRA mRNA alternative form		 CTD PMID:11564422 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Thrap3 thyroid hormone receptor associated protein 3 decreases expression ISO Clozapine results in decreased expression of THRAP3 protein CTD PMID:34122009 NCBI chr 5:138,445,284...138,487,544
Ensembl chr 5:138,445,295...138,487,477 		JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP Clozapine results in decreased expression of THRB mRNA alternative form CTD PMID:11564422 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Tln2 talin 2 decreases expression ISO Clozapine results in decreased expression of TLN2 protein CTD PMID:34122009 NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 decreases expression ISO Clozapine results in decreased expression of TM9SF2 protein CTD PMID:34122009 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049 		JBrowse link
G Tmed10 transmembrane p24 trafficking protein 10 decreases expression ISO Clozapine results in decreased expression of TMED10 protein CTD PMID:34122009 NCBI chr 6:104,991,843...105,026,705
Ensembl chr 6:104,991,838...105,026,753 		JBrowse link
G Tmem109 transmembrane protein 109 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of TMEM109 protein CTD PMID:34122009 NCBI chr 1:207,519,628...207,530,245
Ensembl chr 1:207,519,624...207,530,215 		JBrowse link
G Tmpo thymopoietin decreases expression ISO Clozapine results in decreased expression of TMPO protein CTD PMID:34122009 NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Tnf tumor necrosis factor affects response to substance
increases secretion
multiple interactions
increases expression		 ISO
EXP		 TNF protein affects the susceptibility to Clozapine
Clozapine results in increased secretion of TNF protein
belnacasan inhibits the reaction [Clozapine results in increased secretion of TNF protein]
Clozapine results in increased expression of TNF protein		 CTD PMID:20521320 PMID:24709159 PMID:34935985 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf15 TNF superfamily member 15 decreases expression ISO Clozapine results in decreased expression of TNFSF15 mRNA CTD PMID:17346280 NCBI chr 5:77,134,885...77,156,171
Ensembl chr 5:77,139,878...77,156,228 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase decreases expression ISO Clozapine results in decreased expression of TNIK mRNA CTD PMID:14647396 NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750 		JBrowse link
G Top1mt DNA topoisomerase I mitochondrial increases expression ISO Clozapine results in increased expression of TOP1MT protein CTD PMID:34122009 NCBI chr 7:107,338,092...107,368,125
Ensembl chr 7:107,342,527...107,366,049 		JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions		 ISO Clozapine results in increased expression of TP53 mRNA
CSF3 protein inhibits the reaction [Clozapine results in increased expression of TP53 mRNA]		 CTD PMID:16160616 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Clozapine results in increased expression of TPI1 mRNA CTD PMID:15860345 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Tpm2 tropomyosin 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of TPM2 protein CTD PMID:34122009 NCBI chr 5:57,770,919...57,780,278
Ensembl chr 5:57,770,864...57,779,992 		JBrowse link
G Tpm3 tropomyosin 3 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of TPM3 protein CTD PMID:34122009 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Tpm4 tropomyosin 4 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of TPM4 protein CTD PMID:34122009 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984 		JBrowse link
G Tpr translocated promoter region, nuclear basket protein decreases expression ISO Clozapine results in decreased expression of TPR protein CTD PMID:34122009 NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496 		JBrowse link
G Tra2b transformer 2 beta decreases expression ISO Clozapine results in decreased expression of TRA2B protein CTD PMID:34122009 NCBI chr11:78,788,880...78,807,252
Ensembl chr11:78,788,884...78,807,249 		JBrowse link
G Trim2 tripartite motif-containing 2 decreases expression ISO Clozapine results in decreased expression of TRIM2 mRNA CTD PMID:14647396 NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927 		JBrowse link
G Trim28 tripartite motif-containing 28 decreases expression ISO Clozapine results in decreased expression of TRIM28 protein CTD PMID:34122009 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
G Tspan3 tetraspanin 3 decreases expression
increases expression		 ISO Clozapine results in decreased expression of TSPAN3 protein
Clozapine results in increased expression of TSPAN3 protein		 CTD PMID:34122009 PMID:36482696 NCBI chr 8:56,546,067...56,569,815
Ensembl chr 8:56,546,069...56,569,880 		JBrowse link
G Ttbk1 tau tubulin kinase 1 increases expression ISO Clozapine results in increased expression of TTBK1 protein CTD PMID:34122009 NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774 		JBrowse link
G Ttr transthyretin decreases expression
increases expression		 ISO
EXP		 Clozapine results in decreased expression of TTR mRNA
Clozapine results in increased expression of TTR mRNA; Clozapine results in increased expression of TTR protein		 CTD PMID:15927202 PMID:17266109 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Ttyh2 tweety family member 2 increases expression ISO Clozapine results in increased expression of TTYH2 protein CTD PMID:34122009 NCBI chr10:99,709,063...99,753,449
Ensembl chr10:99,709,007...99,753,444 		JBrowse link
G Tubal3 tubulin, alpha-like 3 increases expression ISO Clozapine results in increased expression of TUBAL3 protein CTD PMID:34122009 NCBI chr17:66,323,733...66,332,423
Ensembl chr17:66,323,733...66,335,355 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of TUBB4B protein CTD PMID:34122009 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Tubb5 tubulin, beta 5 class I increases expression ISO Clozapine results in increased expression of TUBB protein CTD PMID:34122009 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Tubb6 tubulin, beta 6 class V decreases expression ISO Clozapine results in decreased expression of TUBB6 protein CTD PMID:34122009 NCBI chr18:60,943,394...60,953,031
Ensembl chr18:60,943,375...60,954,418 		JBrowse link
G Uap1l1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 increases expression ISO Clozapine results in increased expression of UAP1L1 protein CTD PMID:34122009 NCBI chr 3:8,172,335...8,180,505
Ensembl chr 3:8,173,216...8,180,443 		JBrowse link
G Uba2 ubiquitin-like modifier activating enzyme 2 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in increased expression of UBA2 protein CTD PMID:34122009 NCBI chr 1:86,775,239...86,802,685
Ensembl chr 1:86,775,244...86,802,682 		JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 increases expression ISO Clozapine results in increased expression of UBA52 mRNA CTD PMID:14647396 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807 		JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 affects expression ISO Clozapine affects the expression of UBE2R2 mRNA CTD PMID:14647396 NCBI chr 5:56,286,604...56,345,160
Ensembl chr 5:56,286,725...56,345,513 		JBrowse link
G Ubtf upstream binding transcription factor decreases expression ISO Clozapine results in decreased expression of UBTF protein CTD PMID:34122009 NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression ISO Clozapine results in increased expression of UGT1A1 mRNA CTD PMID:18227147 NCBI chr 9:88,801,344...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation ISO UGT1A4 protein SNP results in increased glucuronidation of Clozapine CTD PMID:15708967 NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
G Unc13a unc-13 homolog A decreases expression EXP Clozapine results in decreased expression of UNC13A mRNA CTD PMID:15860345 NCBI chr16:18,333,910...18,381,813
Ensembl chr16:18,336,229...18,381,872 		JBrowse link
G Unc45b unc-45 myosin chaperone B increases expression ISO Clozapine results in increased expression of UNC45B protein CTD PMID:34122009 NCBI chr10:67,845,464...67,873,143
Ensembl chr10:67,845,462...67,873,389 		JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI affects expression ISO Clozapine affects the expression of UQCR11 mRNA CTD PMID:14647396 NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750 		JBrowse link
G Usp34 ubiquitin specific peptidase 34 increases expression ISO Clozapine results in increased expression of USP34 protein CTD PMID:34122009 NCBI chr14:97,285,799...97,476,376
Ensembl chr14:97,286,018...97,476,376 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 increases expression ISO Clozapine results in increased expression of USP5 protein CTD PMID:34122009 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
G Utp18 UTP18 small subunit processome component increases expression ISO Clozapine results in increased expression of UTP18 protein CTD PMID:34122009 NCBI chr10:78,811,879...78,839,338
Ensembl chr10:78,811,880...78,839,627 		JBrowse link
G Vamp1 vesicle-associated membrane protein 1 increases expression EXP Clozapine results in increased expression of VAMP1 mRNA CTD PMID:15860345 NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 increases expression EXP Clozapine results in increased expression of VAMP2 mRNA CTD PMID:15860345 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vapa VAMP associated protein A increases expression ISO Clozapine results in increased expression of VAPA protein CTD PMID:34122009 NCBI chr 9:105,177,904...105,208,400
Ensembl chr 9:105,177,907...105,207,847 		JBrowse link
G Vapb VAMP associated protein B and C multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of VAPB protein CTD PMID:34122009 NCBI chr 3:162,535,974...162,578,747
Ensembl chr 3:162,535,905...162,573,763 		JBrowse link
G Vcl vinculin increases expression ISO Clozapine results in increased expression of VCL protein CTD PMID:34122009 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Vdac1 voltage-dependent anion channel 1 decreases expression ISO Clozapine results in decreased expression of VDAC1 protein CTD PMID:34122009 NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640 		JBrowse link
G Vsnl1 visinin-like 1 decreases expression EXP Clozapine results in decreased expression of VSNL1 mRNA CTD PMID:12437575 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Clozapine] results in decreased expression of WARS1 protein CTD PMID:34122009 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Wbp1l WW domain binding protein 1-like decreases expression ISO Clozapine results in decreased expression of WBP1L mRNA CTD PMID:14647396 NCBI chr 1:245,472,292...245,528,627
Ensembl chr 1:245,472,296...245,528,627 		JBrowse link
G Wdr12 WD repeat domain 12 decreases expression ISO Clozapine results in decreased expression of WDR12 protein CTD PMID:34122009 NCBI chr 9:61,475,498...61,502,762
Ensembl chr 9:61,475,517...61,502,469 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Clozapine results in increased expression of WIPI1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression ISO Clozapine results in decreased expression of YWHAB mRNA CTD PMID:17266109 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105 		JBrowse link
G Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta increases expression ISO Clozapine results in increased expression of YWHAQ protein CTD PMID:34122009 NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 decreases expression ISO Clozapine results in decreased expression of ZC3HAV1 protein CTD PMID:34122009 NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428 		JBrowse link
droperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions		 ISO Droperidol results in decreased activity of KCNH2 protein
Droperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]		 CTD PMID:16757186 PMID:21158687 PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Droperidol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
etazolate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il13 interleukin 13 decreases expression
decreases secretion		 ISO Etazolate results in decreased expression of IL13 mRNA
Etazolate results in decreased secretion of IL13 protein		 CTD PMID:16083514 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Ltc4s leukotriene C4 synthase decreases secretion ISO Etazolate results in decreased secretion of LTC4S protein CTD PMID:16083514 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651 		JBrowse link
flupenthixol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases activity		 ISO Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]; Flupenthixol analog inhibits the reaction [ABCB1 protein results in decreased susceptibility to Vincristine]
Flupenthixol analog results in decreased activity of ABCB1 protein; Flupenthixol analog results in decreased activity of ABCB1 protein mutant form		 CTD PMID:7905786 PMID:12711602 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Drd1 dopamine receptor D1 affects binding ISO Flupenthixol binds to DRD1 protein CTD PMID:1352677 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Flupenthixol results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 decreases expression ISO Flupenthixol results in decreased expression of PTGS1 protein CTD PMID:8897462 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO Flupenthixol results in decreased expression of PTGS2 protein CTD PMID:8897462 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
fluphenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alad aminolevulinate dehydratase multiple interactions
decreases activity		 EXP [Fluphenazine co-treated with diphenyldiselenide] results in decreased activity of ALAD protein
Fluphenazine results in decreased activity of ALAD protein		 CTD PMID:19486337 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474 		JBrowse link
G Ar androgen receptor multiple interactions ISO Fluphenazine binds to and results in decreased activity of AR protein CTD PMID:17606915 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Cat catalase multiple interactions
increases activity		 EXP diphenyldiselenide inhibits the reaction [Fluphenazine results in increased activity of CAT protein] CTD PMID:19486337 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 decreases activity ISO Fluphenazine results in decreased activity of CYP2C19 protein CTD PMID:15135088 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Fluphenazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity ISO Fluphenazine results in decreased activity of CYP3A4 protein CTD PMID:15135088 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Drd2 dopamine receptor D2 affects binding ISO Fluphenazine binds to DRD2 protein CTD PMID:17606915 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding ISO Fluphenazine binds to HTR2A protein CTD PMID:17606915 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding ISO Fluphenazine binds to HTR2C protein CTD PMID:17606915 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Ngf nerve growth factor multiple interactions EXP Fluphenazine inhibits the reaction [NGF protein results in increased uptake of Calcium] CTD PMID:1374475 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Prl prolactin increases secretion ISO Fluphenazine results in increased secretion of PRL protein CTD PMID:9989566 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Fluphenazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Tac1 tachykinin, precursor 1 decreases expression ISO Fluphenazine results in decreased expression of TAC1 mRNA CTD PMID:15845098 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tfeb transcription factor EB affects localization ISO Fluphenazine affects the localization of TFEB protein CTD PMID:28366621 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714 		JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression EXP Fluphenazine results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715 		JBrowse link
haloperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
decreases expression
decreases activity		 ISO Haloperidol inhibits the reaction [ABCB1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of ABCB1 mRNA
Haloperidol results in decreased activity of ABCB1 protein		 CTD PMID:15946544 PMID:16810505 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases expression		 ISO Haloperidol inhibits the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of ABCC1 mRNA		 CTD PMID:15946544 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Haloperidol inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain decreases expression ISO Haloperidol results in decreased expression of ACADVL protein CTD PMID:34122009 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075 		JBrowse link
G Acat1 acetyl-CoA acetyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of ACAT1 protein CTD PMID:34122009 NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ACSL3 protein CTD PMID:34122009 NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Adam1a ADAM metallopeptidase domain 1a decreases expression EXP Haloperidol results in decreased expression of ADAM1A mRNA CTD PMID:16715494 NCBI chr12:35,017,433...35,020,300
Ensembl chr12:35,017,315...35,020,311 		JBrowse link
G Adcy5 adenylate cyclase 5 affects response to substance
multiple interactions		 ISO ADCY5 protein affects the susceptibility to Haloperidol
SCH 23390 inhibits the reaction [ADCY5 protein affects the susceptibility to Haloperidol]		 CTD PMID:12223546 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I affects expression ISO Haloperidol affects the expression of ADCYAP1R1 mRNA CTD PMID:27900577 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Adora2a adenosine A2a receptor affects response to substance ISO ADORA2A protein affects the susceptibility to Haloperidol CTD PMID:11172060 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Adsl adenylosuccinate lyase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ADSL protein CTD PMID:34122009 NCBI chr 7:112,479,256...112,503,439
Ensembl chr 7:112,479,271...112,503,760 		JBrowse link
G Agpat1 1-acylglycerol-3-phosphate O-acyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of AGPAT1 mRNA CTD PMID:14647396 NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278 		JBrowse link
G Agps alkylglycerone phosphate synthase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of AGPS protein CTD PMID:34122009 NCBI chr 3:60,747,323...60,845,831
Ensembl chr 3:60,747,323...60,845,830 		JBrowse link
G Ak4 adenylate kinase 4 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of AK4 protein CTD PMID:34122009 NCBI chr 5:116,039,222...116,099,064
Ensembl chr 5:116,039,616...116,098,618 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases expression EXP Haloperidol results in decreased expression of AKT1 mRNA CTD PMID:15860345 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 increases expression EXP Haloperidol results in increased expression of AKT2 mRNA CTD PMID:15860345 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 decreases expression ISO Haloperidol results in decreased expression of ALDH18A1 protein CTD PMID:34122009 NCBI chr 1:239,375,657...239,407,956
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP Haloperidol results in increased expression of ALDOA mRNA CTD PMID:15860345 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression EXP Haloperidol results in increased expression of ALDOC mRNA CTD PMID:15860345 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Ankhd1 ankyrin repeat and KH domain containing 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of ANKHD1 protein CTD PMID:34122009 NCBI chr18:28,161,882...28,260,917
Ensembl chr18:28,162,311...28,268,024 		JBrowse link
G Ap2a2 adaptor related protein complex 2 subunit alpha 2 decreases expression EXP Haloperidol results in decreased expression of AP2A2 mRNA CTD PMID:15860345 NCBI chr 1:196,652,315...196,725,609
Ensembl chr 1:196,652,337...196,725,603 		JBrowse link
G Ap2b1 adaptor related protein complex 2 subunit beta 1 affects expression EXP Haloperidol affects the expression of AP2B1 mRNA CTD PMID:15860345 NCBI chr10:68,099,397...68,205,023
Ensembl chr10:68,099,547...68,205,013 		JBrowse link
G Ap2m1 adaptor related protein complex 2 subunit mu 1 increases expression ISO Haloperidol results in increased expression of AP2M1 protein CTD PMID:34122009 NCBI chr11:80,355,307...80,364,218
Ensembl chr11:80,328,041...80,364,140 		JBrowse link
G Ap3b1 adaptor related protein complex 3 subunit beta 1 increases expression ISO Haloperidol results in increased expression of AP3B1 protein CTD PMID:34122009 NCBI chr 2:25,600,069...25,800,937
Ensembl chr 2:25,600,040...25,800,935 		JBrowse link
G Apod apolipoprotein D increases expression ISO Haloperidol results in increased expression of APOD mRNA CTD PMID:14647396 NCBI chr11:69,431,261...69,452,306
Ensembl chr11:69,431,260...69,452,305 		JBrowse link
G Appl1 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of APPL1 protein CTD PMID:34122009 NCBI chr16:2,118,503...2,166,741
Ensembl chr16:2,121,255...2,166,692 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression
multiple interactions		 EXP Haloperidol results in increased expression of ARC mRNA
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of ARC mRNA]		 CTD PMID:18208916 PMID:19695244 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Arf1 ADP-ribosylation factor 1 decreases expression EXP Haloperidol results in decreased expression of ARF1 mRNA CTD PMID:15860345 NCBI chr10:43,997,983...44,014,461
Ensembl chr10:43,997,986...44,014,434 		JBrowse link
G Arf3 ADP-ribosylation factor 3 decreases expression EXP Haloperidol results in decreased expression of ARF3 mRNA CTD PMID:15860345 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002 		JBrowse link
G Arl3 ADP ribosylation factor like GTPase 3 decreases expression EXP Haloperidol results in decreased expression of ARL3 mRNA CTD PMID:15860345 NCBI chr 1:245,400,659...245,446,673
Ensembl chr 1:245,400,550...245,446,820 		JBrowse link
G Arl5a ADP-ribosylation factor like GTPase 5A decreases expression EXP Haloperidol results in decreased expression of ARL5A mRNA CTD PMID:15860345 NCBI chr 3:36,878,461...36,903,362
Ensembl chr 3:36,880,712...36,903,211 		JBrowse link
G Arpc4 actin related protein 2/3 complex, subunit 4 increases expression ISO Haloperidol results in increased expression of ARPC4 mRNA CTD PMID:14647396 NCBI chr 4:146,522,255...146,532,784
Ensembl chr 4:146,522,176...146,532,785 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) decreases expression ISO Haloperidol results in decreased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Asph aspartate-beta-hydroxylase increases expression ISO Haloperidol results in increased expression of ASPH protein CTD PMID:34122009 NCBI chr 5:22,601,581...22,814,107
Ensembl chr 5:22,603,486...22,813,876 		JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 decreases expression EXP Haloperidol results in decreased expression of ATP1A1 mRNA CTD PMID:15860345 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837 		JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 decreases expression EXP Haloperidol results in decreased expression of ATP1A3 mRNA CTD PMID:15860345 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918 		JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 increases expression EXP Haloperidol results in increased expression of ATP1B1 mRNA CTD PMID:15860345 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459 		JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 decreases expression EXP Haloperidol results in decreased expression of ATP1B2 mRNA CTD PMID:15860345 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933 		JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression EXP Haloperidol results in increased expression of ATP1B3 mRNA CTD PMID:15860345 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of ATP2A3 protein CTD PMID:34122009 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp6v1b1 ATPase H+ transporting V1 subunit B1 decreases expression ISO Haloperidol results in decreased expression of ATP6V1B1 protein CTD PMID:34122009 NCBI chr 4:116,223,799...116,242,475
Ensembl chr 4:116,223,799...116,242,475 		JBrowse link
G Atp6v1b2 ATPase H+ transporting V1 subunit B2 decreases expression ISO Haloperidol results in decreased expression of ATP6V1B2 mRNA CTD PMID:16465460 NCBI chr16:20,617,515...20,641,651
Ensembl chr16:20,617,518...20,641,745 		JBrowse link
G Axin2 axin 2 decreases expression EXP Haloperidol results in decreased expression of AXIN2 mRNA CTD PMID:16715494 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression		 EXP Haloperidol results in decreased expression of BAX protein
Haloperidol results in increased expression of BAX mRNA; Haloperidol results in increased expression of BAX protein		 CTD PMID:16462815 PMID:17069804 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcat2 branched chain amino acid transaminase 2 decreases expression ISO Haloperidol results in decreased expression of BCAT2 protein CTD PMID:34122009 NCBI chr 1:96,040,407...96,060,008
Ensembl chr 1:96,042,625...96,060,007 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP Haloperidol results in increased expression of BCL2 protein CTD PMID:17069804 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression
decreases expression		 EXP EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]
Haloperidol results in increased expression of BCL2L1 protein		 CTD PMID:16462815 PMID:17805306 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
decreases expression		 EXP
ISO		 BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; Haloperidol inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]
Haloperidol results in increased expression of BDNF mRNA
Haloperidol results in increased expression of BDNF protein
Haloperidol inhibits the reaction [Cocaine results in decreased expression of BDNF protein]
Haloperidol results in decreased expression of BDNF mRNA; Haloperidol results in decreased expression of BDNF protein		 CTD PMID:11488957 PMID:12393228 PMID:12478621 PMID:15168214 PMID:17442543 More... NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bet1l Bet1 golgi vesicular membrane trafficking protein-like affects expression EXP Haloperidol affects the expression of BET1L mRNA CTD PMID:15860345 NCBI chr 1:195,931,407...195,935,072
Ensembl chr 1:195,931,411...195,935,040 		JBrowse link
G Bop1 BOP1 ribosomal biogenesis factor multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of BOP1 protein CTD PMID:34122009 NCBI chr 7:108,172,062...108,195,875
Ensembl chr 7:108,172,066...108,195,931 		JBrowse link
G Bptf bromodomain PHD finger transcription factor decreases expression ISO Haloperidol results in decreased expression of BPTF mRNA CTD PMID:14647396 NCBI chr10:91,980,279...92,082,731
Ensembl chr10:91,982,758...92,082,769 		JBrowse link
G Cacna1a calcium voltage-gated channel subunit alpha1 A decreases expression EXP
ISO		 Haloperidol results in decreased expression of CACNA1A mRNA CTD PMID:14647396 PMID:16715494 NCBI chr19:23,520,741...23,819,971
Ensembl chr19:23,520,741...23,823,225 		JBrowse link
G Calca calcitonin-related polypeptide alpha affects activity EXP Haloperidol affects the activity of CALCA protein CTD PMID:10075105 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Calm2 calmodulin 2 increases expression EXP Haloperidol results in increased expression of CALM2 mRNA CTD PMID:19289156 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions
increases expression
decreases expression		 EXP Haloperidol results in decreased expression of and results in decreased phosphorylation of CAMK2A protein
Haloperidol results in increased expression of CAMK2A mRNA
Haloperidol results in decreased expression of CAMK2A protein		 CTD PMID:15860345 PMID:18061412 PMID:19289156 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camk2b calcium/calmodulin-dependent protein kinase II beta decreases expression EXP Haloperidol results in decreased expression of CAMK2B mRNA CTD PMID:15860345 NCBI chr14:80,845,206...80,934,172
Ensembl chr14:80,845,238...80,933,994 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta decreases expression EXP Haloperidol results in decreased expression of CAMK2D mRNA CTD PMID:15860345 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression
increases expression		 EXP Haloperidol results in decreased expression of CAMK4 protein
Haloperidol results in increased expression of CAMK4 mRNA		 CTD PMID:15860345 PMID:19289156 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 decreases expression EXP Haloperidol results in decreased expression of CAMKK1 protein CTD PMID:19289156 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression EXP Haloperidol results in decreased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Cap1 cyclase associated actin cytoskeleton regulatory protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CAP1 protein CTD PMID:34122009 NCBI chr 5:135,142,108...135,168,885
Ensembl chr 5:135,142,112...135,168,769 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity		 EXP BDNF protein inhibits the reaction [Haloperidol results in increased activity of CASP3 protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:15168214 PMID:17805306 PMID:18590723 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions
decreases activity
decreases expression		 EXP
ISO		 Carvedilol inhibits the reaction [Haloperidol results in decreased expression of CAT protein]; Haloperidol results in decreased activity of and results in decreased expression of CAT protein; Zolpidem inhibits the reaction [Haloperidol results in decreased activity of CAT]
Haloperidol results in decreased activity of CAT protein
Cannabidiol inhibits the reaction [Haloperidol results in decreased activity of CAT protein]		 CTD PMID:12010767 PMID:12482469 PMID:16564057 PMID:17513028 PMID:30217539 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cbx5 chromobox 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CBX5 protein CTD PMID:34122009 NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022 		JBrowse link
G Ccdc121 coiled-coil domain containing 121 increases expression ISO Haloperidol results in increased expression of CCDC121 protein CTD PMID:34122009 NCBI chr 6:24,970,845...24,973,451
Ensembl chr 6:24,970,833...24,973,478 		JBrowse link
G Cck cholecystokinin increases expression EXP Haloperidol results in increased expression of CCK mRNA CTD PMID:10974607 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP Haloperidol results in decreased expression of CCND1 mRNA CTD PMID:15860345 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd3 cyclin D3 increases expression EXP Haloperidol results in increased expression of CCND3 mRNA CTD PMID:15860345 NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371 		JBrowse link
G Ccnl1 cyclin L1 increases expression EXP Haloperidol results in increased expression of CCNL1 mRNA CTD PMID:15860345 NCBI chr 2:150,184,865...150,199,524
Ensembl chr 2:150,184,798...150,197,368 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CCT8 protein CTD PMID:34122009 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Cdc42 cell division cycle 42 increases expression EXP Haloperidol results in increased expression of CDC42 mRNA CTD PMID:15860345 NCBI chr 5:149,555,069...149,593,239
Ensembl chr 5:149,553,724...149,593,111 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 increases expression EXP Haloperidol results in increased expression of CDK4 mRNA CTD PMID:15860345 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdk5 cyclin-dependent kinase 5 increases expression EXP Haloperidol results in increased expression of CDK5 mRNA CTD PMID:15860345 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112 		JBrowse link
G Cfap161 cilia and flagella associated protein 161 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CFAP161 protein CTD PMID:34122009 NCBI chr 1:137,743,783...137,768,685
Ensembl chr 1:137,743,784...137,768,730 		JBrowse link
G Cfdp1 craniofacial development protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CFDP1 protein CTD PMID:34122009 NCBI chr19:39,718,313...39,823,824
Ensembl chr19:39,718,347...39,823,824 		JBrowse link
G Cfl1 cofilin 1 increases expression ISO Haloperidol results in increased expression of CFL1 protein CTD PMID:34122009 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Chl1 cell adhesion molecule L1-like decreases expression ISO Haloperidol results in decreased expression of CHL1 mRNA CTD PMID:14647396 NCBI chr 4:136,291,504...136,505,830
Ensembl chr 4:136,291,463...136,503,265 		JBrowse link
G Chn1 chimerin 1 decreases expression ISO Haloperidol results in decreased expression of CHN1 mRNA CTD PMID:14647396 NCBI chr 3:58,509,822...58,676,462
Ensembl chr 3:58,510,536...58,676,490 		JBrowse link
G Chordc1 cysteine and histidine rich domain containing 1 increases expression ISO Haloperidol results in increased expression of CHORDC1 protein CTD PMID:34122009 NCBI chr 8:15,374,356...15,398,436
Ensembl chr 8:15,374,471...15,399,162 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects response to substance ISO CHRM4 affects the susceptibility to Haloperidol CTD PMID:21269601 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Cldn11 claudin 11 decreases expression ISO Haloperidol results in decreased expression of CLDN11 mRNA CTD PMID:17177202 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050 		JBrowse link
G Clta clathrin, light chain A affects expression EXP Haloperidol affects the expression of CLTA mRNA CTD PMID:15860345 NCBI chr 5:58,244,253...58,263,480
Ensembl chr 5:58,245,442...58,263,472 		JBrowse link
G Cltb clathrin, light chain B decreases expression EXP Haloperidol results in decreased expression of CLTB mRNA CTD PMID:15860345 NCBI chr17:10,001,512...10,019,201
Ensembl chr17:10,001,513...10,019,169 		JBrowse link
G Cmya5 cardiomyopathy associated 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of CMYA5 protein CTD PMID:34122009 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364 		JBrowse link
G Cnot3 CCR4-NOT transcription complex, subunit 3 decreases expression ISO Haloperidol results in decreased expression of CNOT3 protein CTD PMID:34122009 NCBI chr 1:65,555,924...65,572,167
Ensembl chr 1:65,555,924...65,572,167 		JBrowse link
G Cnp 2',3'-cyclic nucleotide 3' phosphodiesterase decreases expression ISO Haloperidol results in decreased expression of CNP mRNA CTD PMID:17177202 NCBI chr10:85,511,164...85,517,723
Ensembl chr10:85,511,160...85,517,720 		JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
increases methylation		 ISO
EXP		 CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]]
Haloperidol results in increased methylation of CNR1 promoter
Haloperidol inhibits the reaction [Methylazoxymethanol Acetate results in decreased methylation of CNR1 promoter]		 CTD PMID:28017790 PMID:30496751 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Coil coilin increases expression EXP Haloperidol results in increased expression of COIL mRNA CTD PMID:16715494 NCBI chr10:73,789,077...73,810,378
Ensembl chr10:73,789,488...73,810,393 		JBrowse link
G Cops3 COP9 signalosome subunit 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of COPS3 protein CTD PMID:34122009 NCBI chr10:44,618,115...44,652,807
Ensembl chr10:44,618,115...44,641,597 		JBrowse link
G Cops4 COP9 signalosome subunit 4 decreases expression ISO Haloperidol results in decreased expression of COPS4 protein CTD PMID:34122009 NCBI chr14:9,078,579...9,108,788
Ensembl chr14:9,078,576...9,108,887 		JBrowse link
G Cpn1 carboxypeptidase N subunit 1 increases expression EXP Haloperidol results in increased expression of CPN1 mRNA CTD PMID:16715494 NCBI chr 1:242,844,575...242,873,465
Ensembl chr 1:242,844,212...242,873,465 		JBrowse link
G Cpne3 copine 3 decreases expression ISO Haloperidol results in decreased expression of CPNE3 protein CTD PMID:34122009 NCBI chr 5:33,014,658...33,063,934
Ensembl chr 5:33,016,307...33,063,934 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions
increases activity
increases phosphorylation		 ISO
EXP		 Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of CREB1 protein]
Amphetamine affects the reaction [Haloperidol results in increased activity of CREB1 protein modified form]		 CTD PMID:12125044 PMID:12871586 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Haloperidol results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Crhbp corticotropin releasing hormone binding protein decreases expression EXP Haloperidol results in decreased expression of CRHBP mRNA CTD PMID:16715494 NCBI chr 2:26,692,403...26,704,710
Ensembl chr 2:26,692,403...26,704,710 		JBrowse link
G Cry1 cryptochrome circadian regulator 1 decreases expression ISO Haloperidol results in decreased expression of CRY1 mRNA CTD PMID:27746588 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091 		JBrowse link
G Csnk2a1 casein kinase 2 alpha 1 decreases expression EXP Haloperidol results in decreased expression of CSNK2A1 mRNA CTD PMID:16715494 NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696 		JBrowse link
G Cst3 cystatin C increases expression ISO Haloperidol results in increased expression of CST3 mRNA CTD PMID:14647396 NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Haloperidol results in decreased expression of CTNNB1 mRNA
Haloperidol results in increased expression of CTNNB1 protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]		 CTD PMID:16144542 PMID:18797397 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctrl chymotrypsin-like increases expression EXP Haloperidol results in increased expression of CTRL mRNA CTD PMID:16715494 NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626 		JBrowse link
G Ctsk cathepsin K increases expression EXP Haloperidol results in increased expression of CTSK mRNA CTD PMID:16715494 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Cyb5r1 cytochrome b5 reductase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of CYB5R1 protein CTD PMID:34122009 NCBI chr13:45,849,017...45,855,458
Ensembl chr13:45,849,091...45,855,458 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects response to substance ISO CYP2D6 protein polymorphism affects the susceptibility to Haloperidol CTD PMID:15538130 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol; Fluoxetine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; Fluvoxamine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; nefazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; norfluoxetine inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol]; Trazodone inhibits the reaction [CYP3A4 protein results in increased oxidation of and results in increased activity of Haloperidol] CTD PMID:12584149 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol; Fluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Fluvoxamine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; nefazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; norfluoxetine inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol]; Trazodone inhibits the reaction [CYP3A5 protein results in increased oxidation of and results in increased activity of Haloperidol] CTD PMID:12584149 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Dcaf6 DDB1 and CUL4 associated factor 6 decreases expression ISO Haloperidol results in decreased expression of DCAF6 mRNA CTD PMID:14647396 NCBI chr13:77,626,257...77,727,645
Ensembl chr13:77,626,307...77,727,512 		JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression ISO
EXP		 Haloperidol results in increased expression of DCLK1 mRNA CTD PMID:15860345 PMID:18797397 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956 		JBrowse link
G Ddx27 DEAD-box helicase 27 increases expression ISO Haloperidol results in increased expression of DDX27 protein CTD PMID:34122009 NCBI chr 3:155,744,182...155,763,380
Ensembl chr 3:155,744,150...155,763,372 		JBrowse link
G Ddx46 DEAD-box helicase 46 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of DDX46 protein CTD PMID:34122009 NCBI chr17:8,942,070...8,988,440
Ensembl chr17:8,944,454...8,988,439 		JBrowse link
G Ddx5 DEAD-box helicase 5 decreases expression ISO Haloperidol results in decreased expression of DDX5 protein CTD PMID:34122009 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Dennd10 DENN domain containing 10 increases expression EXP Haloperidol results in increased expression of DENND10 mRNA CTD PMID:16715494 NCBI chr 1:259,950,955...259,974,459
Ensembl chr 1:259,950,866...259,974,455 		JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO Haloperidol results in increased expression of DEPP1 mRNA CTD PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Dgka diacylglycerol kinase, alpha decreases expression EXP Haloperidol results in decreased expression of DGKA mRNA CTD PMID:15860345 NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110 		JBrowse link
G Dhx36 DEAH-box helicase 36 decreases expression ISO Haloperidol results in decreased expression of DHX36 protein CTD PMID:34122009 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Dhx38 DEAH-box helicase 38 decreases expression ISO Haloperidol results in decreased expression of DHX38 protein CTD PMID:34122009 NCBI chr19:37,512,893...37,530,135
Ensembl chr19:37,512,891...37,530,140 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression EXP Haloperidol results in decreased expression of DLAT mRNA CTD PMID:15860345 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479 		JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 increases expression ISO Haloperidol results in increased expression of DLG2 protein CTD PMID:34122009 NCBI chr 1:144,451,653...146,503,949
Ensembl chr 1:144,451,472...146,499,475 		JBrowse link
G Dnah1 dynein, axonemal, heavy chain 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of DNAH1 protein CTD PMID:34122009 NCBI chr16:6,455,514...6,517,103
Ensembl chr16:6,456,002...6,518,350 		JBrowse link
G Dnah3 dynein, axonemal, heavy chain 3 increases expression ISO Haloperidol results in increased expression of DNAH3 protein CTD PMID:34122009 NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of DNAJB1 protein CTD PMID:34122009 NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458 		JBrowse link
G Dnajb11 DnaJ heat shock protein family (Hsp40) member B11 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Haloperidol] results in increased expression of DNAJB11 protein
Haloperidol results in increased expression of DNAJB11 protein		 CTD PMID:34122009 NCBI chr11:78,151,750...78,168,259
Ensembl chr11:78,150,429...78,180,407 		JBrowse link
G Dpf1 double PHD fingers 1 increases expression ISO Haloperidol results in increased expression of DPF1 mRNA CTD PMID:14647396 NCBI chr 1:84,602,212...84,615,954
Ensembl chr 1:84,602,336...84,615,950 		JBrowse link
G Dr1 down-regulator of transcription 1 decreases expression ISO Haloperidol results in decreased expression of DR1 protein CTD PMID:34122009 NCBI chr14:1,458,223...1,469,578
Ensembl chr14:1,458,223...1,469,638 		JBrowse link
G Drd1 dopamine receptor D1 affects binding
increases expression
decreases expression
affects activity		 ISO
EXP		 Haloperidol binds to DRD1 protein
Haloperidol results in increased expression of DRD1 protein
Haloperidol results in decreased expression of DRD1 mRNA
Haloperidol affects the activity of DRD1 protein		 CTD PMID:8750706 PMID:8794996 PMID:12887421 PMID:16983399 PMID:23611293 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 affects binding
affects activity
multiple interactions
increases expression
affects response to substance		 ISO
EXP		 DRD2 protein binds to Haloperidol; DRD2 protein binds to Haloperidol analog; Haloperidol binds to DRD2 protein
Haloperidol affects the activity of DRD2 protein
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein; cyclo(leucylglycine) inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of CTNNB1 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]; DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]; felbamate inhibits the reaction [Haloperidol affects the activity of DRD2 protein]; Haloperidol binds to and results in decreased activity of DRD2 protein; Haloperidol inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein] which results in increased uptake of Dopamine]; Haloperidol inhibits the reaction [iodosulpride binds to DRD2 protein]; Haloperidol inhibits the reaction [Spiperone binds to DRD2 protein]; Haloperidol promotes the reaction [Dopamine binds to DRD2 protein]; zinc chloride inhibits the reaction [Haloperidol binds to DRD2 protein]
Haloperidol results in increased expression of DRD2; Haloperidol results in increased expression of DRD2 mRNA; Haloperidol results in increased expression of DRD2 protein
Haloperidol binds to DRD2; Haloperidol binds to DRD2 protein; Haloperidol binds to DRD2 protein alternative form
[Haloperidol binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Ethanol; [Haloperidol results in increased expression of DRD2 protein] which results in decreased susceptibility to Pentobarbital; Haloperidol binds to and results in decreased activity of DRD2 protein
DRD2 affects the susceptibility to Haloperidol; DRD2 protein affects the susceptibility to Haloperidol
Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 mRNA]; Thioctic Acid inhibits the reaction [Haloperidol results in increased expression of DRD2 protein]		 CTD PMID:1351265 PMID:1361536 PMID:1380082 PMID:2945998 PMID:7845605 More... NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 affects binding
multiple interactions		 ISO
EXP		 DRD3 protein binds to Haloperidol analog
Haloperidol affects the reaction [Methylazoxymethanol Acetate results in increased expression of DRD3 mRNA]		 CTD PMID:14552778 PMID:32360362 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 affects activity
affects binding		 ISO
EXP		 Haloperidol affects the activity of DRD4 protein
Haloperidol binds to Drd4 protein		 CTD
RGD		 PMID:23611293 PMID:8078498 RGD:7248459 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Drp2 dystrophin related protein 2 increases expression EXP Haloperidol results in increased expression of DRP2 mRNA alternative form CTD PMID:16715494 NCBI chr  X:97,607,577...97,658,117
Ensembl chr  X:97,607,719...97,655,684 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 increases response to substance
affects response to substance		 ISO DTNBP1 gene polymorphism results in increased susceptibility to Haloperidol
DTNBP1 protein affects the susceptibility to Haloperidol		 CTD PMID:19369910 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661 		JBrowse link
G Dusp1 dual specificity phosphatase 1 decreases expression EXP Haloperidol results in decreased expression of DUSP1 mRNA CTD PMID:15860345 NCBI chr10:16,680,478...16,683,275 JBrowse link
G Dusp6 dual specificity phosphatase 6 decreases expression EXP Haloperidol results in decreased expression of DUSP6 mRNA CTD PMID:15860345 NCBI chr 7:34,092,848...34,097,186
Ensembl chr 7:34,092,943...34,097,185 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 multiple interactions
increases expression		 EXP DRD2 protein affects the reaction [Haloperidol results in increased expression of DVL3 protein] CTD PMID:16144542 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of EEF1G protein CTD PMID:34122009 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382 		JBrowse link
G Egr1 early growth response 1 affects expression
multiple interactions
increases expression		 EXP
ISO		 Haloperidol affects the expression of EGR1 protein
Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]]
Haloperidol results in increased expression of EGR1 mRNA; Haloperidol results in increased expression of EGR1 protein		 CTD PMID:12243769 PMID:16452686 PMID:17028028 PMID:17913375 PMID:18208916 More... NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 affects expression
increases expression
decreases expression		 ISO
EXP		 Haloperidol affects the expression of EGR2 mRNA
Haloperidol results in increased expression of EGR2 mRNA
Haloperidol results in decreased expression of EGR2 protein		 CTD PMID:17028028 PMID:18208916 PMID:19401217 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Eif2b5 eukaryotic translation initiation factor 2B subunit epsilon increases expression ISO Haloperidol results in increased expression of EIF2B5 protein CTD PMID:34122009 NCBI chr11:80,394,433...80,404,468
Ensembl chr11:80,394,433...80,404,419 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of EIF5A protein CTD PMID:34122009 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation
multiple interactions		 ISO
EXP		 Haloperidol results in increased phosphorylation of ELK1 protein
Nifedipine affects the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]
SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of ELK1 protein]		 CTD PMID:12871586 PMID:17913375 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Eno1 enolase 1 increases expression EXP Haloperidol results in increased expression of ENO1 mRNA CTD PMID:15860345 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Epo erythropoietin multiple interactions EXP EPO protein inhibits the reaction [Haloperidol results in decreased expression of BCL2L1 protein]; EPO protein inhibits the reaction [Haloperidol results in decreased expression of BDNF protein]; EPO protein inhibits the reaction [Haloperidol results in increased expression of CASP3 protein] CTD PMID:17805306 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Erap1 endoplasmic reticulum aminopeptidase 1 decreases expression ISO Haloperidol results in decreased expression of ERAP1 protein CTD PMID:34122009 NCBI chr 2:3,931,817...3,970,735
Ensembl chr 2:3,931,904...3,972,447 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 multiple interactions EXP Haloperidol results in increased expression of and results in increased phosphorylation of ERBB2 protein CTD PMID:26961615 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 increases expression
multiple interactions		 EXP Haloperidol results in increased expression of ERBB4 protein
Haloperidol results in increased expression of and results in increased phosphorylation of ERBB4 protein		 CTD PMID:18184445 PMID:26961615 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ergic1 endoplasmic reticulum-golgi intermediate compartment 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of ERGIC1 protein CTD PMID:34122009 NCBI chr10:16,531,192...16,626,974
Ensembl chr10:16,531,194...16,626,957 		JBrowse link
G Ezr ezrin decreases expression ISO Haloperidol results in decreased expression of EZR protein CTD PMID:34122009 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G Fabp3 fatty acid binding protein 3 affects response to substance
increases expression		 ISO FABP3 affects the susceptibility to Haloperidol
Haloperidol results in increased expression of FABP3 protein		 CTD PMID:20181611 PMID:34122009 NCBI chr 5:142,651,962...142,658,707
Ensembl chr 5:142,651,956...142,658,718 		JBrowse link
G Fasn fatty acid synthase increases expression ISO Haloperidol results in increased expression of FASN mRNA CTD PMID:16027736 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Haloperidol results in decreased expression of FLT1 protein CTD PMID:34122009 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Haloperidol results in increased expression of FNDC4 mRNA CTD PMID:17175557 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression		 ISO
EXP		 8-Hydroxy-2-(di-n-propylamino)tetralin affects the reaction [Haloperidol results in increased expression of FOS protein]; Dizocilpine Maleate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; ifenprodil inhibits the reaction [Haloperidol results in increased expression of FOS protein]; tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]; traxoprodil mesylate inhibits the reaction [Haloperidol results in increased expression of FOS protein]; WAY 100135 inhibits the reaction [tandospirone inhibits the reaction [Haloperidol results in increased expression of FOS protein]]
Haloperidol results in increased expression of FOS mRNA; Haloperidol results in increased expression of FOS protein
Haloperidol results in decreased expression of FOS mRNA; Haloperidol results in decreased expression of FOS protein
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]; Clozapine affects the reaction [Haloperidol results in increased expression of FOS protein]; Dronabinol promotes the reaction [Haloperidol results in increased expression of FOS protein]; Nifedipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Nimodipine affects the reaction [Haloperidol results in increased expression of FOS protein]; Propranolol inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of FOS protein]; Theophylline inhibits the reaction [Haloperidol results in increased expression of FOS mRNA]		 CTD PMID:1393566 PMID:9571656 PMID:9748542 PMID:10199625 PMID:10435392 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosb FosB proto-oncogene, AP-1 transcription factor subunit increases expression
multiple interactions		 ISO
EXP		 Haloperidol results in increased expression of FOSB protein alternative form
Haloperidol results in increased expression of FOSB modified form; Haloperidol results in increased expression of FOSB mRNA; Haloperidol results in increased expression of FOSB protein
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of FOSB mRNA]		 CTD PMID:8714707 PMID:11180499 PMID:12243769 PMID:15579174 PMID:19695244 More... NCBI chr 1:78,954,312...78,961,492
Ensembl chr 1:78,954,115...78,961,465 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP Amphetamine affects the reaction [Haloperidol results in increased expression of FOSL1 protein]
Haloperidol results in increased expression of FOSL1 mRNA; Haloperidol results in increased expression of FOSL1 protein		 CTD PMID:12125044 PMID:18208916 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Fosl2 FOS like 2, AP-1 transcription factor subunit increases expression EXP Haloperidol results in increased expression of FOSL2 mRNA CTD PMID:12243769 NCBI chr 6:24,297,898...24,319,219
Ensembl chr 6:24,300,956...24,320,034 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase multiple interactions
increases phosphorylation
affects response to substance		 ISO FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein]
Haloperidol results in increased phosphorylation of FYN protein
FYN protein affects the susceptibility to Haloperidol		 CTD PMID:16407246 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 decreases expression ISO Haloperidol results in decreased expression of GABRA1 mRNA CTD PMID:18797397 NCBI chr10:26,595,151...26,650,611
Ensembl chr10:26,595,160...26,650,864 		JBrowse link
G Gabrb3 gamma-aminobutyric acid type A receptor subunit beta 3 increases expression EXP Haloperidol results in increased expression of GABRB3 mRNA CTD PMID:18923069 NCBI chr 1:108,467,047...108,702,522
Ensembl chr 1:108,296,124...108,698,961 		JBrowse link
G Gad1 glutamate decarboxylase 1 multiple interactions
increases expression
decreases expression		 EXP [Haloperidol co-treated with Fluvoxamine] affects the expression of GAD1 protein
Haloperidol results in increased expression of GAD1 mRNA
Haloperidol results in decreased expression of GAD1 mRNA; Haloperidol results in decreased expression of GAD1 protein		 CTD PMID:12887421 PMID:14519413 PMID:15061247 PMID:15967061 PMID:18923069 More... NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of GAD2 mRNA; Haloperidol results in decreased expression of GAD2 protein
Haloperidol results in increased expression of GAD2 mRNA		 CTD PMID:18923069 PMID:19359144 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GALNT2 protein CTD PMID:34122009 NCBI chr19:52,213,226...52,324,816
Ensembl chr19:52,213,351...52,324,813 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP Haloperidol results in increased expression of GAPDH mRNA CTD PMID:15860345 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gda guanine deaminase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of GDA protein CTD PMID:34122009 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Haloperidol results in increased expression of GDPD3 mRNA CTD PMID:17175557 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO Haloperidol results in decreased expression of GFAP protein CTD PMID:34122009 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gimap5 GTPase, IMAP family member 5 decreases expression EXP Haloperidol results in decreased expression of GIMAP5 mRNA CTD PMID:16715494 NCBI chr 4:77,693,417...77,701,025
Ensembl chr 4:77,687,564...77,703,086 		JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP Haloperidol results in decreased expression of GJA1 protein CTD PMID:18585900 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582 		JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GLO1 protein CTD PMID:34122009 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649 		JBrowse link
G Glul glutamate-ammonia ligase decreases expression EXP Haloperidol results in decreased expression of GLUL mRNA CTD PMID:15860345 NCBI chr13:65,969,053...66,035,121
Ensembl chr13:66,025,630...66,035,108 		JBrowse link
G Gna12 G protein subunit alpha 12 decreases expression EXP Haloperidol results in decreased expression of GNA12 mRNA CTD PMID:15860345 NCBI chr12:13,805,580...13,886,255
Ensembl chr12:13,805,698...13,886,255 		JBrowse link
G Gnai1 G protein subunit alpha i1 decreases expression EXP Haloperidol results in decreased expression of GNAI1 mRNA CTD PMID:15860345 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 decreases expression EXP Haloperidol results in decreased expression of GNAI2 mRNA CTD PMID:15860345 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 decreases expression EXP Haloperidol results in decreased expression of GNAI3 mRNA CTD PMID:15860345 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gnao1 G protein subunit alpha o1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of GNAO1 protein CTD PMID:34122009 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnas GNAS complex locus decreases expression EXP Haloperidol results in decreased expression of GNAS mRNA CTD PMID:15860345 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gnrh1 gonadotropin releasing hormone 1 multiple interactions EXP Haloperidol inhibits the reaction [manganese chloride results in increased secretion of GNRH1 protein] CTD PMID:18603625 NCBI chr15:41,972,482...41,976,690
Ensembl chr15:41,972,905...41,973,581
Ensembl chr15:41,972,905...41,973,581 		JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 affects expression
multiple interactions		 EXP
ISO		 Haloperidol affects the expression of GOT2 mRNA
[Cuprizone co-treated with Haloperidol] results in increased expression of GOT2 protein		 CTD PMID:15860345 PMID:34122009 NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994 		JBrowse link
G Gpx1 glutathione peroxidase 1 increases expression ISO Haloperidol results in increased expression of GPX1 mRNA CTD PMID:14647396 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 decreases expression EXP Haloperidol results in decreased expression of GRIA1 mRNA CTD PMID:15860345 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grik2 glutamate ionotropic receptor kainate type subunit 2 increases expression EXP Haloperidol results in increased expression of GRIK2 mRNA CTD PMID:18923069 NCBI chr20:52,135,325...52,833,061
Ensembl chr20:52,133,851...52,838,375 		JBrowse link
G Grik4 glutamate ionotropic receptor kainate type subunit 4 increases expression EXP Haloperidol results in increased expression of GRIK4 mRNA CTD PMID:15860345 NCBI chr 8:42,903,043...43,331,990
Ensembl chr 8:42,905,056...43,193,751 		JBrowse link
G Grik5 glutamate ionotropic receptor kainate type subunit 5 increases expression ISO
EXP		 Haloperidol results in increased expression of GRIK5 mRNA CTD PMID:14647396 PMID:15860345 NCBI chr 1:80,605,878...80,667,896
Ensembl chr 1:80,605,892...80,667,125 		JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of GRIN1 mRNA
Haloperidol results in increased expression of GRIN1 mRNA		 CTD PMID:12020038 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A decreases expression EXP Haloperidol results in decreased expression of GRIN2A mRNA; Haloperidol results in decreased expression of GRIN2A protein CTD PMID:12608697 PMID:15860345 PMID:18061412 NCBI chr10:5,629,683...6,053,262
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B multiple interactions
increases phosphorylation		 ISO FYN gene mutant form inhibits the reaction [Haloperidol results in increased phosphorylation of GRIN2B protein] CTD PMID:16407246 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Grin2c glutamate ionotropic receptor NMDA type subunit 2C increases expression EXP Haloperidol results in increased expression of GRIN2C mRNA CTD PMID:15860345 NCBI chr10:100,488,430...100,507,083
Ensembl chr10:100,488,431...100,506,427 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases expression EXP Haloperidol results in decreased expression of GRIN2D mRNA CTD PMID:18923069 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Grin3b glutamate ionotropic receptor NMDA type subunit 3B increases expression EXP Haloperidol results in increased expression of GRIN3B mRNA CTD PMID:15860345 NCBI chr 7:9,730,861...9,737,183
Ensembl chr 7:9,730,862...9,737,183 		JBrowse link
G Grk6 G protein-coupled receptor kinase 6 decreases expression EXP Haloperidol results in decreased expression of GRK6 mRNA CTD PMID:16715494 NCBI chr17:9,177,018...9,192,813
Ensembl chr17:9,177,019...9,192,644 		JBrowse link
G Grm1 glutamate metabotropic receptor 1 increases expression EXP Haloperidol results in increased expression of GRM1 mRNA CTD PMID:15860345 NCBI chr 1:5,058,285...5,453,170
Ensembl chr 1:5,058,292...5,453,170 		JBrowse link
G Grm2 glutamate metabotropic receptor 2 increases expression EXP Haloperidol results in increased expression of GRM2 mRNA CTD PMID:18923069 NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions		 EXP Haloperidol results in increased expression of GSK3A protein
DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3A protein]		 CTD PMID:16144542 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases expression		 EXP DRD2 protein affects the reaction [Haloperidol results in increased expression of GSK3B protein]
Haloperidol results in increased expression of GSK3B mRNA; Haloperidol results in increased expression of GSK3B protein		 CTD PMID:16144542 PMID:19359144 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 increases expression EXP Haloperidol results in increased expression of GSTM1 mRNA CTD PMID:15860345 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression EXP Haloperidol results in decreased expression of GSTM2 mRNA CTD PMID:15860345 NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions
decreases expression		 ISO Haloperidol inhibits the reaction [GSTP1 protein results in decreased susceptibility to Doxorubicin]
Haloperidol results in decreased expression of GSTP1 mRNA		 CTD PMID:15946544 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Gtf2e1 general transcription factor IIE subunit 1 decreases expression ISO Haloperidol results in decreased expression of GTF2E1 protein CTD PMID:34122009 NCBI chr11:63,182,073...63,215,349
Ensembl chr11:63,182,349...63,213,942 		JBrowse link
G H2ac18 H2A clustered histone 18 increases expression ISO Haloperidol results in increased expression of H2AC18 mRNA CTD PMID:14647396 NCBI chr 2:183,808,398...183,808,992 JBrowse link
G H2ac20 H2A clustered histone 20 increases expression ISO Haloperidol results in increased expression of H2AC20 protein CTD PMID:34122009 NCBI chr 2:183,779,879...183,780,357 JBrowse link
G H2aj H2A.J histone increases expression ISO Haloperidol results in increased expression of H2AJ protein CTD PMID:34122009 NCBI chr 4:169,675,718...169,676,202
Ensembl chr 4:169,675,752...169,677,006 		JBrowse link
G Hadhb hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HADHB protein CTD PMID:34122009 NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869 		JBrowse link
G Hars1 histidyl-tRNA synthetase 1 increases expression ISO Haloperidol results in increased expression of HARS1 protein CTD PMID:34122009 NCBI chr18:28,381,649...28,398,699
Ensembl chr18:28,381,655...28,398,740 		JBrowse link
G Hcfc1 host cell factor C1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HCFC1 protein CTD PMID:34122009 NCBI chr  X:151,687,779...151,712,688
Ensembl chr  X:151,687,779...151,712,638 		JBrowse link
G Higd1a HIG1 hypoxia inducible domain family, member 1A increases expression ISO Haloperidol results in increased expression of HIGD1A mRNA CTD PMID:14647396 NCBI chr 8:121,514,152...121,523,382
Ensembl chr 8:121,514,156...121,523,443 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases activity
increases expression
multiple interactions		 ISO Haloperidol results in increased activity of HMGCR protein
Haloperidol results in increased expression of HMGCR mRNA
[Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Cholesterol; [Haloperidol results in increased activity of HMGCR protein] which results in increased abundance of Triglycerides		 CTD PMID:16027736 PMID:17052361 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO Haloperidol results in increased expression of HMGCS1 mRNA CTD PMID:16027736 PMID:17052361 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hnrnpc heterogeneous nuclear ribonucleoprotein C multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of HNRNPC protein CTD PMID:34122009 NCBI chr15:24,779,593...24,809,213
Ensembl chr15:24,779,450...24,809,183 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K decreases expression ISO Haloperidol results in decreased expression of HNRNPK protein CTD PMID:34122009 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G Homer1 homer scaffold protein 1 multiple interactions
increases expression		 EXP Cycloserine inhibits the reaction [Haloperidol results in increased expression of HOMER1 mRNA] CTD PMID:12464447 PMID:15860345 PMID:20147574 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Hpcal4 hippocalcin-like 4 decreases expression EXP Haloperidol results in decreased expression of HPCAL4 mRNA CTD PMID:12437575 NCBI chr 5:135,454,477...135,466,417
Ensembl chr 5:135,454,540...135,466,416 		JBrowse link
G Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 decreases expression ISO Haloperidol results in decreased expression of HSD17B4 protein CTD PMID:34122009 NCBI chr18:43,328,903...43,417,950
Ensembl chr18:43,328,824...43,417,952 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 decreases expression
multiple interactions		 ISO Haloperidol results in decreased expression of HSPG2 mRNA
HSPG2 gene results in increased susceptibility to [Haloperidol co-treated with Reserpine]		 CTD PMID:20072119 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of HSPH1 protein CTD PMID:34122009 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224 		JBrowse link
G Htr1d 5-hydroxytryptamine receptor 1D decreases expression EXP Haloperidol results in decreased expression of HTR1D mRNA CTD PMID:16715494 NCBI chr 5:148,656,252...148,676,532
Ensembl chr 5:148,674,495...148,675,619 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding
multiple interactions		 EXP
ISO		 Haloperidol binds to HTR2A protein
[Phencyclidine co-treated with Haloperidol] affects the activity of HTR2A protein		 CTD PMID:7520908 PMID:12191584 PMID:15380371 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C decreases expression EXP Haloperidol results in decreased expression of HTR2C mRNA CTD PMID:17868938 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Id2 inhibitor of DNA binding 2 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of ID2 mRNA
Haloperidol results in increased expression of ID2 mRNA		 CTD PMID:12437575 NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400 		JBrowse link
G Ikbip IKBKB interacting protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of IKBIP protein CTD PMID:34122009 NCBI chr 7:25,579,865...25,598,548
Ensembl chr 7:25,579,832...25,605,162 		JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Cannabidiol co-treated with Haloperidol] results in increased expression of IL10 protein CTD PMID:30217539 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO Cannabidiol inhibits the reaction [Haloperidol results in increased expression of IL1B protein] CTD PMID:30217539 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions		 ISO Haloperidol results in increased expression of IL6 mRNA
Cannabidiol inhibits the reaction [Haloperidol results in increased expression of IL6 mRNA]		 CTD PMID:30217539 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ilkap ILK associated serine/threonine phosphatase decreases expression EXP Haloperidol results in decreased expression of ILKAP mRNA CTD PMID:15860345 NCBI chr 9:91,966,440...91,988,791
Ensembl chr 9:91,966,441...91,988,892 		JBrowse link
G Impdh1 inosine monophosphate dehydrogenase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of IMPDH1 protein CTD PMID:34122009 NCBI chr 4:57,801,842...57,817,434
Ensembl chr 4:57,801,831...57,819,076 		JBrowse link
G Inha inhibin subunit alpha decreases expression EXP Haloperidol results in decreased expression of INHA mRNA CTD PMID:16715494 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Haloperidol results in increased expression of INHBE mRNA CTD PMID:17175557 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression
decreases expression		 EXP Haloperidol results in increased expression of JUN mRNA; Haloperidol results in increased expression of JUN protein
Haloperidol results in decreased expression of JUN mRNA		 CTD PMID:12093589 PMID:12125044 PMID:15860345 PMID:18208916 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
decreases expression		 EXP 8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of JUNB mRNA]
Haloperidol results in decreased expression of JUNB mRNA		 CTD PMID:12093589 PMID:19695244 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 increases expression ISO Haloperidol results in increased expression of KCNA1 mRNA; Haloperidol results in increased expression of KCNA1 protein CTD PMID:18797397 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 decreases expression ISO Haloperidol results in decreased expression of KCNAB1 mRNA CTD PMID:18797397 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Haloperidol inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Haloperidol results in decreased activity of KCNH2 protein		 CTD PMID:15671647 PMID:16278312 PMID:16494862 PMID:19583963 PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 decreases expression ISO Haloperidol results in decreased expression of KCNIP3 mRNA; Haloperidol results in decreased expression of KCNIP3 protein CTD PMID:18797397 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556 		JBrowse link
G Kdm1a lysine demethylase 1A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KDM1A protein CTD PMID:34122009 NCBI chr 5:148,782,976...148,838,319
Ensembl chr 5:148,782,976...148,838,319 		JBrowse link
G Kdr kinase insert domain receptor increases expression ISO Haloperidol results in increased expression of KDR protein CTD PMID:34122009 NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Kif5c kinesin family member 5C decreases expression ISO Haloperidol results in decreased expression of KIF5C protein CTD PMID:34122009 NCBI chr 3:34,032,082...34,185,597
Ensembl chr 3:34,032,105...34,182,413 		JBrowse link
G Kiz kizuna centrosomal protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of KIZ protein CTD PMID:34122009 NCBI chr 3:134,277,631...134,385,260
Ensembl chr 3:134,277,687...134,385,190 		JBrowse link
G Klc1 kinesin light chain 1 decreases expression ISO Haloperidol results in decreased expression of KLC1 mRNA CTD PMID:18797397 NCBI chr 6:130,823,416...130,866,729
Ensembl chr 6:130,823,419...130,867,031 		JBrowse link
G Klc4 kinesin light chain 4 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KLC4 protein CTD PMID:34122009 NCBI chr 9:14,337,164...14,351,075
Ensembl chr 9:14,337,534...14,351,066 		JBrowse link
G Klhdc2 kelch domain containing 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of KLHDC2 protein CTD PMID:34122009 NCBI chr 6:87,777,183...87,791,609
Ensembl chr 6:87,777,183...87,804,187 		JBrowse link
G Kmt2a lysine methyltransferase 2A decreases expression ISO Haloperidol results in decreased expression of KMT2A mRNA CTD PMID:14647396 NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181 		JBrowse link
G Kpna4 karyopherin subunit alpha 4 increases expression ISO Haloperidol results in increased expression of KPNA4 protein CTD PMID:34122009 NCBI chr 2:153,319,380...153,381,085
Ensembl chr 2:153,324,273...153,381,081 		JBrowse link
G Kras KRAS proto-oncogene, GTPase increases expression EXP Haloperidol results in increased expression of KRAS mRNA CTD PMID:15860345 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Kremen1 kringle containing transmembrane protein 1 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of KREMEN1 protein
Haloperidol results in increased expression of KREMEN1 protein		 CTD PMID:34122009 NCBI chr14:80,081,870...80,147,489
Ensembl chr14:80,084,403...80,147,516 		JBrowse link
G Lamtor3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 increases expression ISO Haloperidol results in increased expression of LAMTOR3 mRNA CTD PMID:14647396 NCBI chr 2:226,411,389...226,423,612
Ensembl chr 2:226,411,400...226,423,607 		JBrowse link
G Ldhb lactate dehydrogenase B decreases expression
increases expression		 ISO
EXP		 Haloperidol results in decreased expression of LDHB mRNA
Haloperidol results in increased expression of LDHB mRNA		 CTD PMID:15860345 PMID:16465460 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression ISO Haloperidol results in increased expression of LDLR mRNA CTD PMID:17052361 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lgals1 galectin 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of LGALS1 protein CTD PMID:34122009 NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345 		JBrowse link
G Lipa lipase A, lysosomal acid type increases expression ISO Haloperidol results in increased expression of LIPA protein CTD PMID:34122009 NCBI chr 1:232,024,351...232,057,735
Ensembl chr 1:232,024,356...232,057,633 		JBrowse link
G Mag myelin-associated glycoprotein decreases expression ISO Haloperidol results in decreased expression of MAG mRNA CTD PMID:17177202 NCBI chr 1:86,148,227...86,163,726
Ensembl chr 1:86,148,228...86,163,656 		JBrowse link
G Map1a microtubule-associated protein 1A increases expression
decreases expression		 EXP
ISO		 Haloperidol results in increased expression of MAP1A mRNA
Haloperidol results in decreased expression of MAP1A protein		 CTD PMID:15860345 PMID:34122009 NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899 		JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP Haloperidol results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 decreases expression EXP Haloperidol results in decreased expression of MAP2K1 mRNA CTD PMID:15860345 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 decreases expression
increases expression		 EXP
ISO		 Haloperidol results in decreased expression of MAP2K2 mRNA
Haloperidol results in increased expression of MAP2K2 mRNA		 CTD PMID:14647396 PMID:15860345 NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 decreases expression EXP Haloperidol results in decreased expression of MAP2K5 mRNA CTD PMID:15860345 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 increases expression EXP Haloperidol results in increased expression of MAP3K1 mRNA CTD PMID:15860345 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 increases expression EXP Haloperidol results in increased expression of MAP3K12 mRNA CTD PMID:15860345 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
decreases expression
multiple interactions		 ISO
EXP		 Haloperidol results in increased phosphorylation of MAPK1 protein
Haloperidol results in decreased expression of MAPK1 mRNA
[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK1 protein]		 CTD PMID:12871586 PMID:15860345 PMID:28017790 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 affects expression EXP Haloperidol affects the expression of MAPK14 mRNA CTD PMID:15860345 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions		 ISO Haloperidol results in increased phosphorylation of MAPK3 protein
[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; Clozapine inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]; CNR1 protein affects the reaction [[potassium perchlorate co-treated with 2-mercapto-1-methylimidazole] inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]]; SL 327 inhibits the reaction [Haloperidol results in increased phosphorylation of MAPK3 protein]		 CTD PMID:12871586 PMID:28017790 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk6 mitogen-activated protein kinase 6 affects expression EXP Haloperidol affects the expression of MAPK6 mRNA CTD PMID:15860345 NCBI chr 8:76,146,650...76,169,767
Ensembl chr 8:76,146,690...76,169,720 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases phosphorylation EXP Haloperidol results in increased phosphorylation of MAPK8 protein CTD PMID:17092607 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 affects expression EXP Haloperidol affects the expression of MAPK9 mRNA CTD PMID:15860345 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapre1 microtubule-associated protein, RP/EB family, member 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of MAPRE1 protein CTD PMID:34122009 NCBI chr 3:142,218,846...142,246,990
Ensembl chr 3:142,212,955...142,246,983 		JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor decreases expression EXP Haloperidol results in decreased expression of MAS1 mRNA CTD PMID:16715494 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709 		JBrowse link
G Mbp myelin basic protein decreases expression ISO Haloperidol results in decreased expression of MBP mRNA CTD PMID:17177202 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Haloperidol results in increased expression of MCAM protein CTD PMID:34122009 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mchr1 melanin-concentrating hormone receptor 1 affects binding ISO Haloperidol binds to MCHR1 protein CTD PMID:16983399 NCBI chr 7:112,761,554...112,764,746
Ensembl chr 7:112,761,554...112,764,032 		JBrowse link
G Mmp10 matrix metallopeptidase 10 decreases expression ISO Haloperidol results in decreased expression of MMP10 protein CTD PMID:34122009 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mog myelin oligodendrocyte glycoprotein decreases expression ISO Haloperidol results in decreased expression of MOG mRNA CTD PMID:17177202 NCBI chr20:1,513,137...1,523,473
Ensembl chr20:1,513,239...1,523,474 		JBrowse link
G Mrps31 mitochondrial ribosomal protein S31 increases expression ISO Haloperidol results in increased expression of MRPS31 protein CTD PMID:34122009 NCBI chr16:69,601,349...69,621,609
Ensembl chr16:69,601,349...69,630,654 		JBrowse link
G Myadm myeloid-associated differentiation marker multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of MYADM protein CTD PMID:34122009 NCBI chr 1:65,864,180...65,874,701
Ensembl chr 1:65,864,173...65,874,035 		JBrowse link
G Myo5b myosin Vb decreases expression ISO Haloperidol results in decreased expression of MYO5B protein CTD PMID:34122009 NCBI chr18:68,038,759...68,341,568
Ensembl chr18:68,038,759...68,338,745 		JBrowse link
G Nap1l3 nucleosome assembly protein 1-like 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NAP1L3 protein CTD PMID:34122009 NCBI chr  X:88,347,595...88,350,393
Ensembl chr  X:88,347,598...88,350,393 		JBrowse link
G Ncan neurocan decreases expression ISO Haloperidol results in decreased expression of NCAN mRNA CTD PMID:18797397 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436 		JBrowse link
G Ncaph non-SMC condensin I complex, subunit H decreases expression ISO Haloperidol results in decreased expression of NCAPH protein CTD PMID:34122009 NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180 		JBrowse link
G Ncl nucleolin increases expression ISO Haloperidol results in increased expression of NCL mRNA CTD PMID:14647396 NCBI chr 9:86,999,588...87,008,112
Ensembl chr 9:86,998,019...87,008,136 		JBrowse link
G Ndufv1 NADH:ubiquinone oxidoreductase core subunit V1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of NDUFV1 protein CTD PMID:34122009 NCBI chr 1:201,300,365...201,305,461
Ensembl chr 1:201,299,985...201,305,466 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO Haloperidol results in decreased expression of NEDD4 mRNA CTD PMID:18797397 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression EXP Haloperidol results in decreased expression of NFKB1 protein CTD PMID:16500086 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Ngfr nerve growth factor receptor decreases expression EXP Haloperidol results in decreased expression of NGFR mRNA CTD PMID:16513140 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nifk nucleolar protein interacting with the FHA domain of MKI67 decreases expression ISO Haloperidol results in decreased expression of NIFK protein CTD PMID:34122009 NCBI chr13:29,393,303...29,403,387
Ensembl chr13:29,393,286...29,405,896 		JBrowse link
G Nop14 NOP14 nucleolar protein multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NOP14 protein CTD PMID:34122009 NCBI chr14:76,081,313...76,102,454
Ensembl chr14:76,080,793...76,102,453 		JBrowse link
G Nop53 NOP53 ribosome biogenesis factor increases expression ISO Haloperidol results in increased expression of NOP53 mRNA CTD PMID:14647396 NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO Cannabidiol inhibits the reaction [Haloperidol results in increased expression of NOS2 mRNA] CTD PMID:30217539 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nppa natriuretic peptide A affects activity EXP Haloperidol affects the activity of NPPA protein modified form CTD PMID:1363893 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nptx2 neuronal pentraxin 2 decreases expression EXP Haloperidol results in decreased expression of NPTX2 mRNA CTD PMID:18208916 NCBI chr12:10,037,435...10,048,345
Ensembl chr12:10,037,435...10,048,345 		JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
decreases expression		 EXP Haloperidol promotes the reaction [Amphetamine results in decreased expression of NPY protein]
Haloperidol results in increased expression of NPY protein
Haloperidol results in decreased expression of NPY mRNA		 CTD PMID:7644023 PMID:15985714 PMID:16516965 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of NQO1 protein CTD PMID:34122009 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Haloperidol results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nr1d1 nuclear receptor subfamily 1, group D, member 1 increases expression EXP Haloperidol results in increased expression of NR1D1 mRNA CTD PMID:11564422 NCBI chr10:83,728,348...83,735,562
Ensembl chr10:83,728,318...83,735,705 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 affects response to substance
multiple interactions
increases expression
decreases expression		 ISO
EXP		 NR4A1 affects the susceptibility to Haloperidol
8-Hydroxy-2-(di-n-propylamino)tetralin inhibits the reaction [Haloperidol results in increased expression of NR4A1 mRNA]
Haloperidol results in decreased expression of NR4A1 mRNA		 CTD PMID:10987852 PMID:11564422 PMID:14603264 PMID:19695244 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 increases expression EXP Haloperidol results in increased expression of NR4A3 mRNA CTD PMID:19695244 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Nrg1 neuregulin 1 increases expression EXP Haloperidol results in increased expression of NRG1 protein CTD PMID:18184445 PMID:26961615 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nsf N-ethylmaleimide sensitive factor, vesicle fusing ATPase decreases expression EXP
ISO		 Haloperidol results in decreased expression of NSF mRNA
Haloperidol results in decreased expression of NSF protein		 CTD PMID:15860345 PMID:34122009 NCBI chr10:88,727,912...88,857,375
Ensembl chr10:88,727,912...88,857,386 		JBrowse link
G Nts neurotensin multiple interactions
increases expression		 ISO
EXP		 SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of NTS mRNA; Haloperidol results in increased expression of NTS protein
8-(3-chlorostyryl)caffeine inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]; Theophylline inhibits the reaction [Haloperidol results in increased expression of NTS mRNA]		 CTD PMID:10199625 PMID:11120399 PMID:11602683 PMID:12887421 PMID:14603264 More... NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Numbl NUMB-like, endocytic adaptor protein decreases expression ISO Haloperidol results in decreased expression of NUMBL mRNA CTD PMID:18797397 NCBI chr 1:82,549,814...82,573,788
Ensembl chr 1:82,550,054...82,573,776 		JBrowse link
G Nup54 nucleoporin 54 decreases expression ISO Haloperidol results in decreased expression of NUP54 protein CTD PMID:34122009 NCBI chr14:15,617,630...15,636,029
Ensembl chr14:15,617,679...15,636,028 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Haloperidol results in increased expression of NUPR1 mRNA CTD PMID:17175557 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of OAT protein CTD PMID:34122009 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
G Oprl1 opioid related nociceptin receptor 1 affects response to substance ISO OPRL1 affects the susceptibility to Haloperidol CTD PMID:16237164 NCBI chr 3:168,831,934...168,839,920
Ensembl chr 3:168,834,003...168,839,920 		JBrowse link
G Oprm1 opioid receptor, mu 1 multiple interactions ISO OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] CTD PMID:20184921 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Osbpl8 oxysterol binding protein-like 8 increases expression ISO Haloperidol results in increased expression of OSBPL8 mRNA CTD PMID:14647396 NCBI chr 7:46,596,944...46,749,888
Ensembl chr 7:46,596,983...46,749,888 		JBrowse link
G Park7 Parkinsonism associated deglycase increases expression ISO Haloperidol results in increased expression of PARK7 mRNA CTD PMID:14647396 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pcmt1 protein-L-isoaspartate (D-aspartate) O-methyltransferase 1 decreases expression ISO Haloperidol results in decreased expression of PCMT1 protein CTD PMID:34122009 NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201 		JBrowse link
G Pcsk1n proprotein convertase subtilisin/kexin type 1 inhibitor increases expression ISO Haloperidol results in increased expression of PCSK1N mRNA CTD PMID:14647396 NCBI chr  X:14,580,036...14,583,478
Ensembl chr  X:14,580,038...14,583,566 		JBrowse link
G Pde10a phosphodiesterase 10A increases expression EXP Haloperidol results in increased expression of PDE10A mRNA; Haloperidol results in increased expression of PDE10A protein CTD PMID:18222493 NCBI chr 1:51,765,743...52,218,086
Ensembl chr 1:51,770,132...52,216,563 		JBrowse link
G Pde1b phosphodiesterase 1B increases expression EXP
ISO		 Haloperidol results in increased expression of PDE1B mRNA; Haloperidol results in increased expression of PDE1B protein CTD PMID:14647396 PMID:18222493 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Pde4a phosphodiesterase 4A decreases expression EXP Haloperidol results in decreased expression of PDE4A protein CTD PMID:20222156 NCBI chr 8:19,690,816...19,753,538
Ensembl chr 8:19,703,290...19,751,961 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 decreases expression ISO Haloperidol results in decreased expression of PDLIM5 protein CTD PMID:34122009 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pdzrn3 PDZ domain containing RING finger 3 decreases expression ISO Haloperidol results in decreased expression of PDZRN3 protein CTD PMID:34122009 NCBI chr 4:133,770,736...133,996,959
Ensembl chr 4:133,770,736...133,996,959 		JBrowse link
G Penk proenkephalin multiple interactions
increases expression		 ISO
EXP		 3,4-dicarboxyphenylglycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; Docosahexaenoic Acids inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Tretinoin inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]
Haloperidol results in increased expression of PENK mRNA; Haloperidol results in increased expression of PENK protein
1-aminocyclopentane-1,2,4-tricarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 1-aminoindan-1,5-dicarboxylic acid inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 2-(2,3-dicarboxycyclopropyl)glycine promotes the reaction [Haloperidol results in increased expression of PENK mRNA]; 5-amino-7-(2-phenylethyl)-2-(2-furyl)pyrazolo(4,3-e)-1,2,4-triazolo(1,5-c)pyrimidine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; 6-methyl-2-(phenylethynyl)pyridine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Memantine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]; Scopolamine inhibits the reaction [Haloperidol results in increased expression of PENK mRNA]		 CTD PMID:3838946 PMID:7637876 PMID:12373537 PMID:12727308 PMID:12834887 More... NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Per1 period circadian regulator 1 increases expression ISO Haloperidol results in increased expression of PER1 mRNA CTD PMID:27746588 NCBI chr10:53,800,126...53,814,963
Ensembl chr10:53,805,535...53,814,431 		JBrowse link
G Pfdn5 prefoldin subunit 5 increases expression ISO Haloperidol results in increased expression of PFDN5 mRNA CTD PMID:14647396 NCBI chr 7:133,451,778...133,456,516
Ensembl chr 7:133,451,453...133,456,516 		JBrowse link
G Pfkp phosphofructokinase, platelet increases expression
multiple interactions		 EXP
ISO		 Haloperidol results in increased expression of PFKP mRNA
[Cuprizone co-treated with Haloperidol] results in increased expression of PFKP protein		 CTD PMID:15860345 PMID:34122009 NCBI chr17:63,729,743...63,794,026
Ensembl chr17:63,729,780...63,794,018 		JBrowse link
G Pfn1 profilin 1 increases expression ISO Haloperidol results in increased expression of PFN1 protein CTD PMID:34122009 NCBI chr10:55,365,263...55,367,968
Ensembl chr10:55,365,262...55,527,631 		JBrowse link
G Pgk1 phosphoglycerate kinase 1 increases expression EXP Haloperidol results in increased expression of PGK1 mRNA CTD PMID:15860345 NCBI chr  X:71,271,454...71,287,429
Ensembl chr  X:71,271,440...71,287,418 		JBrowse link
G Phactr1 phosphatase and actin regulator 1 increases expression ISO Haloperidol results in increased expression of PHACTR1 mRNA CTD PMID:14647396 NCBI chr17:21,560,364...22,040,166
Ensembl chr17:21,562,721...22,039,831 		JBrowse link
G Picalm phosphatidylinositol binding clathrin assembly protein decreases expression EXP Haloperidol results in decreased expression of PICALM mRNA CTD PMID:15860345 NCBI chr 1:144,056,415...144,138,045
Ensembl chr 1:144,056,721...144,137,557 		JBrowse link
G Pik3r3 phosphoinositide-3-kinase regulatory subunit 3 decreases expression EXP Haloperidol results in decreased expression of PIK3R3 mRNA CTD PMID:16715494 NCBI chr 5:129,700,925...129,772,591
Ensembl chr 5:129,701,229...129,772,583 		JBrowse link
G Pkib cAMP-dependent protein kinase inhibitor beta decreases expression EXP Haloperidol results in decreased expression of PKIB mRNA CTD PMID:15860345 NCBI chr20:36,965,172...37,062,190
Ensembl chr20:36,905,340...37,062,187 		JBrowse link
G Pkm pyruvate kinase M1/2 increases expression EXP Haloperidol results in increased expression of PKM mRNA CTD PMID:15860345 NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599 		JBrowse link
G Plp1 proteolipid protein 1 decreases expression ISO Haloperidol results in decreased expression of PLP1 mRNA CTD PMID:17177202 PMID:18797397 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Plpbp pyridoxal phosphate binding protein increases expression ISO Haloperidol results in increased expression of PLPBP protein CTD PMID:34122009 NCBI chr16:65,003,292...65,014,886
Ensembl chr16:65,002,223...65,014,886 		JBrowse link
G Pls3 plastin 3 decreases expression ISO Haloperidol results in decreased expression of PLS3 protein CTD PMID:34122009 NCBI chr  X:111,589,193...111,683,908
Ensembl chr  X:111,589,254...111,683,891 		JBrowse link
G Pmpca peptidase, mitochondrial processing subunit alpha increases expression ISO Haloperidol results in increased expression of PMPCA protein CTD PMID:34122009 NCBI chr 3:9,207,731...9,216,846
Ensembl chr 3:9,207,717...9,216,844 		JBrowse link
G Ppa1 inorganic pyrophosphatase 1 increases expression ISO Haloperidol results in increased expression of PPA1 protein CTD PMID:34122009 NCBI chr20:29,590,733...29,617,711
Ensembl chr20:29,590,707...29,619,215 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions ISO [Cannabidiol co-treated with Haloperidol] results in increased expression of PPARGC1A protein CTD PMID:30217539 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Ppm1a protein phosphatase, Mg2+/Mn2+ dependent, 1A decreases expression EXP Haloperidol results in decreased expression of PPM1A mRNA CTD PMID:15860345 NCBI chr 6:91,439,094...91,486,139
Ensembl chr 6:91,438,834...91,480,697 		JBrowse link
G Ppm1b protein phosphatase, Mg2+/Mn2+ dependent, 1B decreases expression EXP Haloperidol results in decreased expression of PPM1B mRNA CTD PMID:15860345 NCBI chr 6:9,646,695...9,707,471
Ensembl chr 6:9,655,765...9,707,974 		JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of PPM1F protein CTD PMID:34122009 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340 		JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta decreases expression EXP Haloperidol results in decreased expression of PPP1CB mRNA CTD PMID:15860345 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824 		JBrowse link
G Ppp1cc protein phosphatase 1 catalytic subunit gamma decreases expression EXP Haloperidol results in decreased expression of PPP1CC mRNA CTD PMID:15860345 NCBI chr12:34,383,072...34,400,553
Ensembl chr12:34,383,072...34,400,553 		JBrowse link
G Ppp1r14b protein phosphatase 1, regulatory (inhibitor) subunit 14B multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of PPP1R14B protein CTD PMID:34122009 NCBI chr 1:204,165,210...204,167,320
Ensembl chr 1:204,163,299...204,167,319 		JBrowse link
G Ppp1r1a protein phosphatase 1, regulatory (inhibitor) subunit 1A decreases expression EXP Haloperidol results in decreased expression of PPP1R1A mRNA CTD PMID:15860345 NCBI chr 7:134,654,578...134,662,236
Ensembl chr 7:134,654,579...134,662,230 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B increases phosphorylation ISO Haloperidol results in increased phosphorylation of PPP1R1B protein CTD PMID:12871586 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Ppp1r2 protein phosphatase 1, regulatory (inhibitor) subunit 2 decreases expression EXP Haloperidol results in decreased expression of PPP1R2 mRNA CTD PMID:15860345 NCBI chr11:69,472,676...69,494,468
Ensembl chr11:69,472,555...69,494,463 		JBrowse link
G Ppp1r9b protein phosphatase 1, regulatory subunit 9B decreases expression EXP Haloperidol results in decreased expression of PPP1R9B protein CTD PMID:16844384 NCBI chr10:79,938,055...79,954,085
Ensembl chr10:79,938,066...79,954,083 		JBrowse link
G Ppp2ca protein phosphatase 2 catalytic subunit alpha decreases expression EXP Haloperidol results in decreased expression of PPP2CA mRNA CTD PMID:15860345 NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862 		JBrowse link
G Ppp2cb protein phosphatase 2 catalytic subunit beta decreases expression EXP Haloperidol results in decreased expression of PPP2CB mRNA CTD PMID:15860345 NCBI chr16:58,558,119...58,579,325
Ensembl chr16:58,558,122...58,579,576 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha increases expression EXP Haloperidol results in increased expression of PPP2R1A mRNA CTD PMID:15860345 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha decreases expression EXP Haloperidol results in decreased expression of PPP2R2A mRNA CTD PMID:15860345 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions
decreases expression		 EXP [Haloperidol binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein
Haloperidol results in decreased expression of PPP3CA mRNA; Haloperidol results in decreased expression of PPP3CA protein		 CTD PMID:16033416 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit decreases expression
multiple interactions		 ISO Haloperidol results in decreased expression of PPP5C mRNA
[Cuprizone co-treated with Haloperidol] results in decreased expression of PPP5C protein		 CTD PMID:14647396 PMID:34122009 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha increases expression EXP Haloperidol results in increased expression of PRKACA mRNA CTD PMID:15860345 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkacb protein kinase cAMP-activated catalytic subunit beta increases expression EXP Haloperidol results in increased expression of PRKACB mRNA CTD PMID:15860345 NCBI chr 2:235,636,878...235,726,928
Ensembl chr 2:235,636,885...235,726,198 		JBrowse link
G Prkar2a protein kinase cAMP-dependent type II regulatory subunit alpha multiple interactions
increases expression		 EXP
ISO		 Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2A protein]
[Cuprizone co-treated with Haloperidol] results in decreased expression of PRKAR2A protein
Haloperidol results in increased expression of PRKAR2A mRNA; Haloperidol results in increased expression of PRKAR2A protein		 CTD PMID:11907174 PMID:34122009 NCBI chr 8:109,393,189...109,458,832
Ensembl chr 8:109,395,833...109,455,628 		JBrowse link
G Prkar2b protein kinase cAMP-dependent type II regulatory subunit beta multiple interactions
increases expression
decreases expression		 EXP Haloperidol promotes the reaction [Cyclic AMP binds to PRKAR2B protein]
Haloperidol results in increased expression of PRKAR2B mRNA; Haloperidol results in increased expression of PRKAR2B protein
Haloperidol results in decreased expression of PRKAR2B mRNA		 CTD PMID:11907174 PMID:15860345 NCBI chr 6:48,563,659...48,653,933
Ensembl chr 6:48,563,662...48,653,933 		JBrowse link
G Prkcb protein kinase C, beta multiple interactions
increases expression		 EXP [Haloperidol co-treated with Fluvoxamine] affects the expression of PRKCB protein
Haloperidol results in increased expression of PRKCB mRNA		 CTD PMID:15860345 PMID:15967061 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkce protein kinase C, epsilon increases expression EXP Haloperidol results in increased expression of PRKCE mRNA CTD PMID:15860345 NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719 		JBrowse link
G Prkcsh PRKCSH beta subunit of glucosidase II multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PRKCSH protein CTD PMID:34122009 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492 		JBrowse link
G Prkcz protein kinase C, zeta increases expression EXP Haloperidol results in increased expression of PRKCZ mRNA CTD PMID:15860345 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Prl prolactin affects expression
increases secretion
multiple interactions
increases expression		 ISO
EXP		 Haloperidol affects the expression of PRL protein
Haloperidol results in increased secretion of PRL protein
Haloperidol inhibits the reaction [Aripiprazole results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [cabergoline results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [Dopamine results in decreased secretion of PRL protein]; Haloperidol inhibits the reaction [talipexole results in decreased secretion of PRL protein]; LHRH, N-acetyl-(4-chlorophenylalanyl)(1)-(4-chlorophenylalanyl)(2)-tryptophyl(3)-arginyl(6)-alanine(10)- inhibits the reaction [Haloperidol results in increased expression of PRL protein]; Triptorelin Pamoate inhibits the reaction [Haloperidol results in increased expression of PRL protein]		 CTD PMID:1304992 PMID:1380082 PMID:2136057 PMID:3019639 PMID:3158510 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 increases expression ISO Haloperidol results in increased expression of PRPF19 protein CTD PMID:34122009 NCBI chr 1:207,541,582...207,552,664
Ensembl chr 1:207,541,595...207,552,662 		JBrowse link
G Prpf38b pre-mRNA processing factor 38B decreases expression ISO Haloperidol results in decreased expression of PRPF38B mRNA CTD PMID:14647396 NCBI chr 2:196,553,224...196,562,271
Ensembl chr 2:196,553,225...196,562,250 		JBrowse link
G Prrc2a proline-rich coiled-coil 2A decreases expression ISO Haloperidol results in decreased expression of PRRC2A mRNA CTD PMID:18797397 NCBI chr20:3,658,391...3,674,143
Ensembl chr20:3,658,695...3,674,130 		JBrowse link
G Prxl2a peroxiredoxin like 2A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PRXL2A protein CTD PMID:34122009 NCBI chr16:16,866,601...16,886,378
Ensembl chr16:16,866,603...16,886,433 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 decreases expression EXP Haloperidol results in decreased expression of PSMB9 mRNA CTD PMID:16452686 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
G Psmd12 proteasome 26S subunit, non-ATPase 12 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PSMD12 protein CTD PMID:34122009 NCBI chr10:92,438,223...92,457,323
Ensembl chr10:92,438,298...92,457,287 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Haloperidol results in increased expression of PTGS2 mRNA CTD PMID:30217539 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptma prothymosin alpha increases expression ISO Haloperidol results in increased expression of PTMA protein CTD PMID:34122009 NCBI chr 9:87,176,251...87,180,333
Ensembl chr 9:87,176,230...87,180,333 		JBrowse link
G Ptms parathymosin increases expression ISO Haloperidol results in increased expression of PTMS mRNA CTD PMID:14647396 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009 		JBrowse link
G Pura purine rich element binding protein A increases expression ISO Haloperidol results in increased expression of PURA protein CTD PMID:34122009 NCBI chr18:27,885,071...27,905,509
Ensembl chr18:27,884,556...27,905,513 		JBrowse link
G Purb purine rich element binding protein B decreases expression ISO Haloperidol results in decreased expression of PURB protein CTD PMID:34122009 NCBI chr14:81,342,374...81,344,857
Ensembl chr14:81,336,448...81,351,432 		JBrowse link
G Pvalb parvalbumin multiple interactions EXP Haloperidol inhibits the reaction [Phencyclidine results in decreased expression of PVALB mRNA] CTD PMID:12589379 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561 		JBrowse link
G Pycr1 pyrroline-5-carboxylate reductase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of PYCR1 protein CTD PMID:34122009 NCBI chr10:105,917,732...105,922,658
Ensembl chr10:105,917,680...105,922,549 		JBrowse link
G Pygm glycogen phosphorylase, muscle associated decreases expression ISO Haloperidol results in decreased expression of PYGM protein CTD PMID:34122009 NCBI chr 1:203,690,550...203,705,369
Ensembl chr 1:203,690,533...203,705,368 		JBrowse link
G Qki QKI, KH domain containing RNA binding increases expression ISO Haloperidol results in increased expression of QKI mRNA alternative form CTD PMID:19335891 NCBI chr 1:50,387,716...50,501,568
Ensembl chr 1:50,387,698...50,498,831 		JBrowse link
G Rab10 RAB10, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB10 mRNA CTD PMID:15860345 NCBI chr 6:26,267,081...26,319,739
Ensembl chr 6:26,266,859...26,320,193 		JBrowse link
G Rab11a RAB11a, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB11A mRNA CTD PMID:15860345 NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525 		JBrowse link
G Rab12 RAB12, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB12 mRNA CTD PMID:12437575 NCBI chr 9:106,480,301...106,506,895
Ensembl chr 9:106,480,301...106,506,910 		JBrowse link
G Rab28 RAB28, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB28 mRNA CTD PMID:15860345 NCBI chr14:69,245,846...69,322,968
Ensembl chr14:69,245,854...69,322,967 		JBrowse link
G Rab4a RAB4A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB4A mRNA CTD PMID:15860345 NCBI chr19:51,795,613...51,822,706
Ensembl chr19:51,795,613...51,822,703 		JBrowse link
G Rab5a RAB5A, member RAS oncogene family multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RAB5A protein CTD PMID:34122009 NCBI chr 9:6,483,906...6,512,877
Ensembl chr 9:6,484,469...6,512,873 		JBrowse link
G Rab6a RAB6A, member RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAB6A mRNA CTD PMID:15860345 NCBI chr 1:154,957,870...155,008,922
Ensembl chr 1:154,958,189...154,996,715 		JBrowse link
G Rab7a RAB7A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB7A mRNA CTD PMID:15860345 NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889 		JBrowse link
G Rab8a RAB8A, member RAS oncogene family decreases expression EXP Haloperidol results in decreased expression of RAB8A mRNA CTD PMID:15860345 NCBI chr16:17,654,027...17,675,385
Ensembl chr16:17,654,034...17,675,678 		JBrowse link
G Rac1 Rac family small GTPase 1 increases expression EXP Haloperidol results in increased expression of RAC1 mRNA CTD PMID:15860345 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rala RAS like proto-oncogene A increases expression EXP Haloperidol results in increased expression of RALA mRNA CTD PMID:15860345 NCBI chr17:47,092,163...47,145,192
Ensembl chr17:47,092,207...47,144,063 		JBrowse link
G Ralb RAS like proto-oncogene B increases expression EXP Haloperidol results in increased expression of RALB mRNA CTD PMID:15860345 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202 		JBrowse link
G Ranbp3 RAN binding protein 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of RANBP3 protein CTD PMID:34122009 NCBI chr 9:1,507,233...1,544,460
Ensembl chr 9:1,507,361...1,544,460 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Haloperidol results in increased expression of RAP1B mRNA CTD PMID:15860345 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO Haloperidol results in decreased expression of RAPGEF4 mRNA CTD PMID:18797397 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Rarb retinoic acid receptor, beta increases expression EXP Haloperidol results in increased expression of RARB mRNA alternative form CTD PMID:11564422 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 affects localization EXP Haloperidol affects the localization of RASGRF1 protein CTD PMID:17092607 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 decreases expression EXP Haloperidol results in decreased expression of RASGRP1 mRNA CTD PMID:15860345 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G Rcn1 reticulocalbin 1 multiple interactions
decreases expression		 ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RCN1 protein
Haloperidol results in decreased expression of RCN1 protein		 CTD PMID:34122009 NCBI chr 3:91,841,052...91,855,295
Ensembl chr 3:91,841,052...91,855,295 		JBrowse link
G Rdh11 retinol dehydrogenase 11 decreases expression ISO Haloperidol results in decreased expression of RDH11 protein CTD PMID:34122009 NCBI chr 6:97,979,377...97,995,252
Ensembl chr 6:97,979,378...97,995,252 		JBrowse link
G Rdx radixin decreases expression ISO Haloperidol results in decreased expression of RDX protein CTD PMID:34122009 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases expression EXP Haloperidol results in increased expression of RELA protein CTD PMID:18554768 PMID:18590723 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Reln reelin decreases expression EXP Haloperidol results in decreased expression of RELN mRNA; Haloperidol results in decreased expression of RELN protein CTD PMID:19359144 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP Haloperidol results in increased expression of RGS2 mRNA CTD PMID:11409749 PMID:11516571 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 increases expression EXP Haloperidol results in increased expression of RGS4 mRNA CTD PMID:15860345 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 increases expression EXP Haloperidol results in increased expression of RGS8 mRNA CTD PMID:15860345 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance ISO RGS9 affects the susceptibility to Haloperidol CTD PMID:15728856 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
G Rhoa ras homolog family member A decreases expression EXP Haloperidol results in decreased expression of RHOA mRNA CTD PMID:15860345 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 decreases expression EXP Haloperidol results in decreased expression of RIMS1 mRNA CTD PMID:15860345 NCBI chr 9:24,696,959...25,196,404
Ensembl chr 9:24,698,854...25,196,631 		JBrowse link
G Rorb RAR-related orphan receptor B decreases expression EXP Haloperidol results in decreased expression of RORB mRNA CTD PMID:11564422 NCBI chr 1:216,363,629...216,544,390
Ensembl chr 1:216,363,629...216,544,390 		JBrowse link
G Rpl13 ribosomal protein L13 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL13 protein CTD PMID:34122009 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014 		JBrowse link
G Rpl18a ribosomal protein L18A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL18A protein CTD PMID:34122009 NCBI chr16:18,542,555...18,544,578
Ensembl chr16:18,542,566...18,545,546 		JBrowse link
G Rpl19 ribosomal protein L19 decreases expression
multiple interactions		 ISO Haloperidol results in decreased expression of RPL19 protein
[Cuprizone co-treated with Haloperidol] results in increased expression of RPL19 protein		 CTD PMID:34122009 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112 		JBrowse link
G Rpl30 ribosomal protein L30 increases expression ISO Haloperidol results in increased expression of RPL30 protein CTD PMID:34122009 NCBI chr 7:65,648,266...65,651,401
Ensembl chr 7:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363
Ensembl chr10:65,645,991...65,651,363 		JBrowse link
G Rpl6 ribosomal protein L6 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL6 protein CTD PMID:34122009 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921 		JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPL8 protein CTD PMID:34122009 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482
Ensembl chr 3:108,622,324...108,628,482 		JBrowse link
G Rplp0l1 ribosomal protein lateral stalk subunit P0 like 1 decreases expression ISO Haloperidol results in decreased expression of RPLP0P6 protein CTD PMID:34122009 NCBI chr 2:191,921,503...191,922,661
Ensembl chr 2:191,921,574...191,922,646 		JBrowse link
G Rplp2 ribosomal protein lateral stalk subunit P2 increases expression ISO Haloperidol results in increased expression of RPLP2 mRNA CTD PMID:14647396 NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645 		JBrowse link
G Rps10 ribosomal protein S10 increases expression ISO Haloperidol results in increased expression of RPS10 mRNA CTD PMID:14647396 NCBI chr20:5,694,313...5,698,922
Ensembl chr20:5,694,313...5,699,044
Ensembl chr 6:5,694,313...5,699,044 		JBrowse link
G Rps16 ribosomal protein S16 decreases expression ISO Haloperidol results in decreased expression of RPS16 protein CTD PMID:34122009 NCBI chr 1:83,643,066...83,646,056
Ensembl chr 1:83,643,130...83,646,206 		JBrowse link
G Rps27 ribosomal protein S27 increases expression ISO Haloperidol results in increased expression of RPS27 protein CTD PMID:34122009 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964 		JBrowse link
G Rps27a ribosomal protein S27a multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPS27A protein CTD PMID:34122009 NCBI chr14:103,285,734...103,288,011
Ensembl chr14:103,285,734...103,288,011
Ensembl chr 5:103,285,734...103,288,011 		JBrowse link
G Rps9 ribosomal protein S9 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of RPS9 protein CTD PMID:34122009 NCBI chr 1:65,511,723...65,515,076
Ensembl chr 1:65,511,723...65,515,123 		JBrowse link
G Rrad RRAD, Ras related glycolysis inhibitor and calcium channel regulator increases expression EXP Haloperidol results in increased expression of RRAD mRNA CTD PMID:15860345 NCBI chr19:354,184...357,424
Ensembl chr19:354,198...357,417 		JBrowse link
G Rrbp1 ribosome binding protein 1 decreases expression ISO Haloperidol results in decreased expression of RRBP1 protein CTD PMID:34122009 NCBI chr 3:131,314,996...131,376,930
Ensembl chr 3:131,314,998...131,376,981 		JBrowse link
G Rsf1 remodeling and spacing factor 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of RSF1 protein CTD PMID:34122009 NCBI chr 1:151,892,055...152,015,089
Ensembl chr 1:151,892,434...152,009,051 		JBrowse link
G Rtn4 reticulon 4 decreases expression ISO Haloperidol results in decreased expression of RTN4 mRNA CTD PMID:18797397 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Rxrg retinoid X receptor gamma affects response to substance
increases expression		 ISO
EXP		 RXRG protein affects the susceptibility to Haloperidol
Haloperidol results in increased expression of RXRG mRNA alternative form		 CTD PMID:10336693 PMID:11564422 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Haloperidol results in decreased expression of S100A9 mRNA CTD PMID:18797397 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SAE1 protein CTD PMID:34122009 NCBI chr 1:77,030,961...77,086,937
Ensembl chr 1:77,030,965...77,086,986 		JBrowse link
G Sars1 seryl-tRNA synthetase 1 decreases expression ISO Haloperidol results in decreased expression of SARS1 protein CTD PMID:34122009 NCBI chr 2:196,065,543...196,081,240
Ensembl chr 2:196,065,430...196,081,277 		JBrowse link
G Satb2 SATB homeobox 2 decreases expression ISO Haloperidol results in decreased expression of SATB2 protein CTD PMID:34122009 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707 		JBrowse link
G Sbds Sbds, ribosome maturation factor multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of SBDS protein CTD PMID:34122009 NCBI chr12:26,420,410...26,429,650
Ensembl chr12:26,420,414...26,429,649 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO Haloperidol results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO Haloperidol results in increased expression of SCD mRNA CTD PMID:16027736 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562 		JBrowse link
G Sec61a1 SEC61 translocon subunit alpha 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SEC61A1 protein CTD PMID:34122009 NCBI chr 4:120,973,519...120,987,871
Ensembl chr 4:120,960,626...120,987,925 		JBrowse link
G Sec63 SEC63 homolog, protein translocation regulator increases expression ISO Haloperidol results in increased expression of SEC63 protein CTD PMID:34122009 NCBI chr20:46,245,101...46,314,055
Ensembl chr20:46,245,101...46,314,055 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N increases expression ISO Haloperidol results in increased expression of SERPINA3 mRNA; Haloperidol results in increased expression of SERPINA3 protein CTD PMID:17175557 PMID:34122009 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO Haloperidol results in decreased expression of SERPINI1 mRNA CTD PMID:18797397 NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135 		JBrowse link
G Sf3b4 splicing factor 3B subunit 4 decreases expression ISO Haloperidol results in decreased expression of SF3B4 protein CTD PMID:34122009 NCBI chr 2:183,732,791...183,737,545
Ensembl chr 2:183,732,754...183,737,959 		JBrowse link
G Sgcd sarcoglycan, delta multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SGCD protein CTD PMID:34122009 NCBI chr10:31,346,480...32,328,364
Ensembl chr10:31,280,511...31,724,840 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression EXP Haloperidol results in increased expression of SGK1 mRNA CTD PMID:16452686 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Sh3kbp1 SH3 domain-containing kinase-binding protein 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SH3KBP1 protein CTD PMID:34122009 NCBI chr  X:34,877,862...35,223,013
Ensembl chr  X:34,877,866...35,222,747 		JBrowse link
G Sh3pxd2b SH3 and PX domains 2B multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of SH3PXD2B protein CTD PMID:34122009 NCBI chr10:16,918,611...17,027,499
Ensembl chr10:16,918,679...17,005,170 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Haloperidol results in increased expression of SLC17A6 mRNA; Haloperidol results in increased expression of SLC17A6 protein CTD PMID:18155072 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 affects response to substance ISO SLC17A8 protein affects the susceptibility to Haloperidol CTD PMID:18278042 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects binding ISO Haloperidol binds to SLC18A2 protein CTD PMID:7912402 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc1a1 solute carrier family 1 member 1 decreases expression EXP Haloperidol results in decreased expression of SLC1A1 mRNA CTD PMID:12873733 NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 decreases expression EXP Haloperidol results in decreased expression of SLC1A2 mRNA CTD PMID:12873733 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc1a3 solute carrier family 1 member 3 decreases expression EXP Haloperidol results in decreased expression of SLC1A3 mRNA CTD PMID:15860345 NCBI chr 2:57,755,495...57,830,605
Ensembl chr 2:57,755,497...57,830,605 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Haloperidol inhibits the reaction [SLC22A2 protein results in increased uptake of Tetraethylammonium] CTD PMID:23770354 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc25a3 solute carrier family 25 member 3 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SLC25A3 protein CTD PMID:34122009 NCBI chr 7:25,611,937...25,619,401
Ensembl chr 7:25,586,725...25,667,727 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO Haloperidol results in increased expression of SLC2A4 mRNA CTD PMID:16002093 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc39a7 solute carrier family 39 member 7 increases expression ISO Haloperidol results in increased expression of SLC39A7 mRNA CTD PMID:14647396 NCBI chr20:4,823,166...4,826,538
Ensembl chr20:4,822,012...4,826,537 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
increases expression		 ISO
EXP		 SLC6A3 protein promotes the reaction [Haloperidol results in increased expression of NTS mRNA]
Haloperidol results in increased expression of SLC6A3 protein		 CTD PMID:14698760 PMID:17069804 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 increases expression EXP Haloperidol results in increased expression of SLC6A4 CTD PMID:12007678 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Snap25 synaptosome associated protein 25 affects response to substance
affects expression		 ISO
EXP		 SNAP25 gene SNP affects the susceptibility to Haloperidol
Haloperidol affects the expression of SNAP25 mRNA		 CTD PMID:15823421 PMID:15860345 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Snrpd2 small nuclear ribonucleoprotein D2 polypeptide increases expression ISO Haloperidol results in increased expression of SNRPD2 mRNA CTD PMID:14647396 NCBI chr 1:78,798,377...78,801,227
Ensembl chr 1:78,798,377...78,803,351 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions		 EXP Haloperidol results in increased expression of SOD1 mRNA
Haloperidol results in decreased expression of SOD1 protein
Clozapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Haloperidol results in decreased activity of and results in decreased expression of SOD1 protein; olanzapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; Risperidone inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]		 CTD PMID:12482469 PMID:12752374 PMID:16564057 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 decreases expression
multiple interactions		 EXP Haloperidol results in decreased expression of SOD2 mRNA; Haloperidol results in decreased expression of SOD2 protein
Haloperidol results in decreased activity of and results in decreased expression of SOD2 protein		 CTD PMID:12482469 PMID:15860345 PMID:16564057 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP Haloperidol results in increased expression of SOD3 mRNA CTD PMID:15860345 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Speg striated muscle enriched protein kinase increases expression ISO Haloperidol results in increased expression of SPEG protein CTD PMID:34122009 NCBI chr 9:76,865,714...76,923,170
Ensembl chr 9:76,865,754...76,923,144 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO Haloperidol results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Srpra SRP receptor subunit alpha decreases expression ISO Haloperidol results in decreased expression of SRPRA protein CTD PMID:34122009 NCBI chr 8:33,560,365...33,566,458
Ensembl chr 8:33,560,348...33,566,470 		JBrowse link
G Srsf2 serine and arginine rich splicing factor 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SRSF2 protein CTD PMID:34122009 NCBI chr10:102,052,158...102,055,365
Ensembl chr10:102,052,314...102,055,338 		JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of SRSF5 protein CTD PMID:34122009 NCBI chr 6:100,605,165...100,610,192
Ensembl chr 6:100,605,456...100,610,177 		JBrowse link
G Stip1 stress-induced phosphoprotein 1 decreases expression ISO Haloperidol results in decreased expression of STIP1 protein CTD PMID:34122009 NCBI chr 1:204,209,433...204,228,452
Ensembl chr 1:204,178,932...204,228,476 		JBrowse link
G Strn4 striatin 4 increases expression ISO Haloperidol results in increased expression of STRN4 mRNA CTD PMID:14647396 NCBI chr 1:77,482,267...77,511,862
Ensembl chr 1:77,482,094...77,511,858 		JBrowse link
G Stt3a STT3 oligosaccharyltransferase complex catalytic subunit A multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of STT3A protein CTD PMID:34122009 NCBI chr 8:36,443,623...36,483,111
Ensembl chr 8:36,446,788...36,483,293 		JBrowse link
G Stx1a syntaxin 1A increases expression EXP Haloperidol results in increased expression of STX1A mRNA CTD PMID:15860345 NCBI chr12:21,641,971...21,670,022
Ensembl chr12:21,641,969...21,669,930 		JBrowse link
G Stx1b syntaxin 1B affects expression EXP Haloperidol affects the expression of STX1B mRNA CTD PMID:15860345 NCBI chr 1:182,415,544...182,434,385
Ensembl chr 1:182,415,546...182,441,280 		JBrowse link
G Stx4 syntaxin 4 increases expression EXP Haloperidol results in increased expression of STX4 mRNA CTD PMID:15860345 NCBI chr 1:182,451,108...182,459,701
Ensembl chr 1:182,451,117...182,459,979 		JBrowse link
G Stx5 syntaxin 5 decreases expression EXP Haloperidol results in decreased expression of STX5 mRNA CTD PMID:15860345 NCBI chr 1:205,637,401...205,653,563
Ensembl chr 1:205,637,413...205,653,563 		JBrowse link
G Stx7 syntaxin 7 decreases expression EXP Haloperidol results in decreased expression of STX7 mRNA CTD PMID:15860345 NCBI chr 1:21,197,075...21,237,320
Ensembl chr 1:21,197,075...21,237,279 		JBrowse link
G Stx8 syntaxin 8 affects expression EXP Haloperidol affects the expression of STX8 mRNA CTD PMID:15860345 NCBI chr10:52,655,643...52,900,048
Ensembl chr10:52,654,990...52,894,993 		JBrowse link
G Supt3h SPT3 homolog, SAGA and STAGA complex component increases expression EXP Haloperidol results in increased expression of SUPT3H mRNA CTD PMID:16715494 NCBI chr 9:15,878,296...16,206,768
Ensembl chr 9:15,868,287...16,206,706 		JBrowse link
G Syn2 synapsin II increases expression EXP Haloperidol results in increased expression of SYN2 mRNA CTD PMID:15860345 NCBI chr 4:148,178,846...148,347,010
Ensembl chr 4:148,186,270...148,344,192 		JBrowse link
G Sypl1 synaptophysin-like 1 decreases expression ISO Haloperidol results in decreased expression of SYPL1 mRNA CTD PMID:18797397 NCBI chr 6:49,565,111...49,585,205
Ensembl chr 6:49,565,154...49,585,330 		JBrowse link
G Syt11 synaptotagmin 11 increases expression EXP Haloperidol results in increased expression of SYT11 mRNA CTD PMID:15860345 NCBI chr 2:174,206,032...174,232,540
Ensembl chr 2:174,206,191...174,231,964 		JBrowse link
G Syt3 synaptotagmin 3 decreases expression EXP Haloperidol results in decreased expression of SYT3 mRNA CTD PMID:15860345 NCBI chr 1:94,880,835...94,895,518
Ensembl chr 1:94,881,247...94,895,246 		JBrowse link
G Syt4 synaptotagmin 4 affects expression EXP Haloperidol affects the expression of SYT4 mRNA CTD PMID:15860345 NCBI chr18:23,036,973...23,046,380
Ensembl chr18:23,038,378...23,046,332 		JBrowse link
G Tac1 tachykinin, precursor 1 increases expression EXP Haloperidol results in increased expression of TAC1 mRNA CTD PMID:10974607 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tagln transgelin decreases expression ISO Haloperidol results in decreased expression of TAGLN mRNA CTD PMID:17175557 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tagln2 transgelin 2 decreases expression ISO Haloperidol results in decreased expression of TAGLN2 protein CTD PMID:34122009 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972 		JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member decreases expression EXP Haloperidol results in decreased expression of TAP1 mRNA CTD PMID:16452686 NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901 		JBrowse link
G Tatdn1 TatD DNase domain containing 1 increases expression ISO Haloperidol results in increased expression of TATDN1 mRNA CTD PMID:14647396 NCBI chr 7:90,449,979...90,481,000
Ensembl chr 7:90,441,079...90,481,133 		JBrowse link
G Tcaf1 TRPM8 channel-associated factor 1 decreases expression ISO Haloperidol results in decreased expression of TCAF1 protein CTD PMID:34122009 NCBI chr 4:71,589,674...71,639,274
Ensembl chr 4:71,591,200...71,613,309 		JBrowse link
G Tcerg1 transcription elongation regulator 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of TCERG1 protein CTD PMID:34122009 NCBI chr18:34,505,708...34,566,470
Ensembl chr18:34,505,751...34,566,470 		JBrowse link
G Tf transferrin decreases expression ISO Haloperidol results in decreased expression of TRF mRNA CTD PMID:17177202 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tgoln2 trans-golgi network protein 2 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of TGOLN2 protein CTD PMID:34122009 NCBI chr 4:104,663,356...104,671,208
Ensembl chr 4:104,663,353...104,671,164 		JBrowse link
G Th tyrosine hydroxylase increases expression EXP Haloperidol results in increased expression of TH protein CTD PMID:17028028 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Thra thyroid hormone receptor alpha decreases expression
increases expression		 EXP Haloperidol results in decreased expression of THRA mRNA alternative form
Haloperidol results in increased expression of THRA mRNA alternative form		 CTD PMID:11564422 NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936 		JBrowse link
G Tln2 talin 2 decreases expression ISO Haloperidol results in decreased expression of TLN2 protein CTD PMID:34122009 NCBI chr 8:67,830,920...68,252,240
Ensembl chr 8:67,834,326...68,252,219 		JBrowse link
G Tm9sf2 transmembrane 9 superfamily member 2 decreases expression ISO Haloperidol results in decreased expression of TM9SF2 protein CTD PMID:34122009 NCBI chr15:99,201,556...99,254,054
Ensembl chr15:99,201,489...99,254,049 		JBrowse link
G Tmem109 transmembrane protein 109 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of TMEM109 protein CTD PMID:34122009 NCBI chr 1:207,519,628...207,530,245
Ensembl chr 1:207,519,624...207,530,215 		JBrowse link
G Tmod3 tropomodulin 3 decreases expression ISO Haloperidol results in decreased expression of TMOD3 protein CTD PMID:34122009 NCBI chr 8:76,248,978...76,310,855
Ensembl chr 8:76,248,979...76,310,977 		JBrowse link
G Tmprss2 transmembrane serine protease 2 increases expression EXP Haloperidol results in increased expression of TMPRSS2 mRNA CTD PMID:32808185 NCBI chr11:36,934,306...36,973,779
Ensembl chr11:36,934,306...36,973,715 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 EXP
ISO		 Haloperidol affects the reaction [Phencyclidine affects the expression of TNF mRNA]
Cannabidiol inhibits the reaction [Haloperidol results in increased expression of TNF mRNA]
Haloperidol results in increased expression of TNF protein		 CTD PMID:16478754 PMID:18554768 PMID:18590723 PMID:30217539 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnik TRAF2 and NCK interacting kinase decreases expression ISO Haloperidol results in decreased expression of TNIK mRNA CTD PMID:14647396 NCBI chr 2:111,184,352...111,587,993
Ensembl chr 2:111,184,387...111,580,750 		JBrowse link
G Tor1a torsin family 1, member A affects response to substance ISO TOR1A gene mutant form affects the susceptibility to Haloperidol CTD PMID:20227500 NCBI chr 3:14,250,667...14,257,704
Ensembl chr 3:14,250,676...14,257,691 		JBrowse link
G Tp53 tumor protein p53 increases expression EXP Haloperidol results in increased expression of TP53 mRNA; Haloperidol results in increased expression of TP53 protein CTD PMID:16462815 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression EXP Haloperidol results in increased expression of TPI1 mRNA CTD PMID:15860345 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Trim2 tripartite motif-containing 2 decreases expression ISO Haloperidol results in decreased expression of TRIM2 mRNA CTD PMID:14647396 NCBI chr 2:169,500,628...169,652,855
Ensembl chr 2:169,500,634...169,652,927 		JBrowse link
G Trim23 tripartite motif-containing 23 decreases expression EXP Haloperidol results in decreased expression of TRIM23 mRNA CTD PMID:15860345 NCBI chr 2:35,302,405...35,335,746
Ensembl chr 2:35,302,409...35,335,743 		JBrowse link
G Trim28 tripartite motif-containing 28 decreases expression ISO Haloperidol results in decreased expression of TRIM28 protein CTD PMID:34122009 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
G Trmt13 tRNA methyltransferase 13 homolog decreases expression ISO Haloperidol results in decreased expression of TRMT13 protein CTD PMID:34122009 NCBI chr 2:204,533,630...204,547,711
Ensembl chr 2:204,533,632...204,546,843 		JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of TRPV5 protein CTD PMID:34122009 NCBI chr 4:70,536,432...70,562,743
Ensembl chr 4:70,536,440...70,562,745 		JBrowse link
G Ttbk1 tau tubulin kinase 1 increases expression ISO Haloperidol results in increased expression of TTBK1 protein CTD PMID:34122009 NCBI chr 9:14,493,166...14,538,372
Ensembl chr 9:14,493,389...14,535,774 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of TUBB4B protein CTD PMID:34122009 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Txlna taxilin alpha multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of TXLNA protein CTD PMID:34122009 NCBI chr 5:141,969,337...141,985,054
Ensembl chr 5:141,969,346...141,984,583 		JBrowse link
G Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 increases expression ISO Haloperidol results in increased expression of UBA52 mRNA CTD PMID:14647396 NCBI chr16:18,918,614...18,920,807
Ensembl chr16:18,900,616...18,920,807 		JBrowse link
G Ubc ubiquitin C multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of UBC protein CTD PMID:34122009 NCBI chr12:31,239,149...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Ube2r2 ubiquitin-conjugating enzyme E2R 2 increases expression ISO Haloperidol results in increased expression of UBE2R2 mRNA CTD PMID:14647396 NCBI chr 5:56,286,604...56,345,160
Ensembl chr 5:56,286,725...56,345,513 		JBrowse link
G Ubqln4 ubiquilin 4 decreases expression ISO Haloperidol results in decreased expression of UBQLN4 protein CTD PMID:34122009 NCBI chr 2:174,012,726...174,028,062
Ensembl chr 2:174,012,777...174,028,059 		JBrowse link
G Ubtf upstream binding transcription factor decreases expression ISO Haloperidol results in decreased expression of UBTF protein CTD PMID:34122009 NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969 		JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 increases expression ISO Haloperidol results in increased expression of UGP2 protein CTD PMID:34122009 NCBI chr14:95,456,330...95,497,483
Ensembl chr14:95,456,330...95,496,830 		JBrowse link
G Ugt8 UDP glycosyltransferase 8 decreases expression ISO Haloperidol results in decreased expression of UGT8A mRNA CTD PMID:17177202 NCBI chr 2:214,264,483...214,332,769
Ensembl chr 2:214,264,483...214,332,660 		JBrowse link
G Unc13a unc-13 homolog A decreases expression EXP Haloperidol results in decreased expression of UNC13A mRNA CTD PMID:15860345 NCBI chr16:18,333,910...18,381,813
Ensembl chr16:18,336,229...18,381,872 		JBrowse link
G Uqcr11 ubiquinol-cytochrome c reductase, complex III subunit XI increases expression ISO Haloperidol results in increased expression of UQCR11 mRNA CTD PMID:14647396 NCBI chr 7:9,305,042...9,309,753
Ensembl chr 7:9,305,058...9,309,750 		JBrowse link
G Uso1 USO1 vesicle transport factor multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of USO1 protein CTD PMID:34122009 NCBI chr14:15,866,638...15,932,185
Ensembl chr14:15,866,638...15,932,171 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 multiple interactions
increases expression		 ISO [Cuprizone co-treated with Haloperidol] results in increased expression of USP5 protein
Haloperidol results in increased expression of USP5 protein		 CTD PMID:34122009 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
G Usp7 ubiquitin specific peptidase 7 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in increased expression of USP7 protein CTD PMID:34122009 NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355 		JBrowse link
G Vamp1 vesicle-associated membrane protein 1 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of VAMP1 mRNA
Haloperidol results in increased expression of VAMP1 mRNA		 CTD PMID:15860345 NCBI chr 4:158,012,634...158,019,350
Ensembl chr 4:158,012,663...158,019,349 		JBrowse link
G Vamp2 vesicle-associated membrane protein 2 decreases expression
increases expression		 EXP Haloperidol results in decreased expression of VAMP2 mRNA
Haloperidol results in increased expression of VAMP2 mRNA		 CTD PMID:15860345 NCBI chr10:53,793,581...53,797,815
Ensembl chr10:53,793,923...53,797,809 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 decreases expression ISO Haloperidol results in decreased expression of VIPR2 mRNA CTD PMID:27900577 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597 		JBrowse link
G Vldlr very low density lipoprotein receptor increases expression EXP Haloperidol results in increased expression of VLDLR protein CTD PMID:19359144 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
G Vsnl1 visinin-like 1 decreases expression EXP Haloperidol results in decreased expression of VSNL1 mRNA CTD PMID:12437575 NCBI chr 6:34,038,641...34,159,479
Ensembl chr 6:34,038,642...34,159,479 		JBrowse link
G Wars1 tryptophanyl-tRNA synthetase 1 multiple interactions ISO [Cuprizone co-treated with Haloperidol] results in decreased expression of WARS1 protein CTD PMID:34122009 NCBI chr 6:127,776,088...127,807,273
Ensembl chr 6:127,776,090...127,807,269 		JBrowse link
G Wbp1l WW domain binding protein 1-like decreases expression ISO Haloperidol results in decreased expression of WBP1L mRNA CTD PMID:14647396 NCBI chr 1:245,472,292...245,528,627
Ensembl chr 1:245,472,296...245,528,627 		JBrowse link
G Wdr12 WD repeat domain 12 decreases expression ISO Haloperidol results in decreased expression of WDR12 protein CTD PMID:34122009 NCBI chr 9:61,475,498...61,502,762
Ensembl chr 9:61,475,517...61,502,469 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Haloperidol results in increased expression of WIPI1 mRNA CTD PMID:17175557 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846 		JBrowse link
G Wwc3 WWC family member 3 decreases expression ISO Haloperidol results in decreased expression of WWC3 protein CTD PMID:34122009 NCBI chr  X:23,584,204...23,701,864
Ensembl chr  X:23,584,424...23,700,513 		JBrowse link
G Xirp2 xin actin-binding repeat containing 2 decreases expression ISO Haloperidol results in decreased expression of XIRP2 protein CTD PMID:34122009 NCBI chr 3:52,126,213...52,213,094
Ensembl chr 3:51,870,092...52,213,091 		JBrowse link
G Xpnpep1 X-prolyl aminopeptidase 1 increases expression ISO Haloperidol results in increased expression of XPNPEP1 protein CTD PMID:34122009 NCBI chr 1:252,001,366...252,052,077
Ensembl chr 1:252,001,367...252,051,479 		JBrowse link
G Zfr zinc finger RNA binding protein decreases expression ISO Haloperidol results in decreased expression of ZFR protein CTD PMID:34122009 NCBI chr 2:61,137,611...61,200,322
Ensembl chr 2:61,137,611...61,200,322 		JBrowse link
iloperidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO iloperidone results in decreased activity of ABCB11 protein CTD PMID:23956101 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases activity
decreases expression		 ISO iloperidone results in decreased activity of CYP3A4 protein
iloperidone results in decreased expression of CYP3A4 mRNA		 CTD PMID:32941854 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
loxapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases metabolic processing ISO CYP1A2 results in increased metabolism of Loxapine CTD PMID:21826677 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 increases metabolic processing ISO CYP2D6 results in increased metabolism of Loxapine CTD PMID:21826677 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases metabolic processing ISO CYP3A4 results in increased metabolism of Loxapine CTD PMID:21826677 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Drd1 dopamine receptor D1 affects binding EXP Loxapine analog binds to DRD1 protein; Loxapine binds to DRD1 protein CTD PMID:9723970 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 affects binding EXP Loxapine analog binds to DRD2 protein; Loxapine binds to DRD2 protein CTD PMID:9723970 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A affects binding EXP Loxapine analog binds to HTR1A protein; Loxapine binds to HTR1A protein CTD PMID:9723970 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding EXP Loxapine analog binds to HTR2A protein; Loxapine binds to HTR2A protein CTD PMID:9723970 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects binding EXP Loxapine analog binds to HTR2C protein; Loxapine binds to HTR2C protein CTD PMID:9723970 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Loxapine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
lurasidone hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Drd2 dopamine receptor D2 multiple interactions ISO Lurasidone Hydrochloride binds to and results in decreased activity of DRD2 protein CTD PMID:20404009 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO Lurasidone Hydrochloride binds to and results in increased activity of HTR1A protein CTD PMID:20404009 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO Lurasidone Hydrochloride binds to and results in decreased activity of HTR7 protein CTD PMID:20404009 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
LY 379268 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions EXP LY 379268 inhibits the reaction [bisphenol A results in decreased expression of NR3C1 mRNA] CTD PMID:25812946 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
mesoridazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Mesoridazine results in decreased activity of KCNH2 protein CTD PMID:17042915 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
methiothepin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adra1a adrenoceptor alpha 1A multiple interactions EXP Methiothepin binds to and results in decreased activity of ADRA1A protein CTD PMID:16545797 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions ISO
EXP		 Methiothepin binds to and results in decreased activity of HTR1A protein CTD PMID:2207497 PMID:15482641 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B affects binding EXP Methiothepin binds to HTR1B protein CTD PMID:11888550 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO [Methiothepin binds to and results in decreased activity of HTR2A protein] which results in decreased susceptibility to Cocaine CTD PMID:10764922 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B multiple interactions EXP methiothepin binds to protein 5-Htr5b; inhibits the reaction[5-carboxamidotryptamine binds to 5-Htr5b] RGD PMID:8224165 RGD:2303647 NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Methiothepin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; [Methiothepin binds to and results in decreased activity of HTR7 protein] which results in decreased abundance of Cyclic AMP; Methiothepin binds to and results in decreased activity of HTR7 protein CTD PMID:14578406 PMID:18996971 PMID:19509219 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Methiothepin results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sigmar1 sigma non-opioid intracellular receptor 1 multiple interactions EXP [N,N-dipropyl-2-(4-methoxy-3-(2-phenylethoxy)phenyl)ethylamine monohydrochloride binds to and results in decreased activity of SIGMAR1 protein] inhibits the reaction [1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone results in increased secretion of Acetylcholine] CTD PMID:11907181 NCBI chr 5:56,904,155...56,907,012
Ensembl chr 5:56,904,159...56,907,017 		JBrowse link
olanzapine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A1bg alpha-1-B glycoprotein affects phosphorylation ISO olanzapine affects the phosphorylation of A1BG protein CTD PMID:25821032 NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097 		JBrowse link
G A2m alpha-2-macroglobulin affects phosphorylation ISO olanzapine affects the phosphorylation of A2M protein CTD PMID:25821032 NCBI chr 4:154,897,770...154,947,787
Ensembl chr 4:154,897,877...154,947,786 		JBrowse link
G Abcb11 ATP binding cassette subfamily B member 11 decreases activity ISO olanzapine results in decreased activity of ABCB11 protein CTD PMID:22646477 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity
multiple interactions		 ISO
EXP		 olanzapine results in decreased activity of ABCB1 protein
[[ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to Fluoxetine] which affects the abundance of Olanzapine; [[ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to Fluoxetine] which results in increased uptake of Olanzapine; [ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] results in increased abundance of and results in decreased uptake of Olanzapine		 CTD PMID:16810505 PMID:34610281 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B multiple interactions EXP [[ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to Fluoxetine] which affects the abundance of Olanzapine; [[ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] affects the susceptibility to Fluoxetine] which results in increased uptake of Olanzapine; [ABCB1A gene mutant form co-treated with ABCB1B gene mutant form] results in increased abundance of and results in decreased uptake of Olanzapine CTD PMID:34610281 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO olanzapine inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Acaca acetyl-CoA carboxylase alpha decreases expression
multiple interactions		 ISO Olanzapine results in decreased expression of ACACA mRNA
capsazepine inhibits the reaction [Olanzapine results in decreased expression of ACACA mRNA]; Metformin inhibits the reaction [Olanzapine results in decreased expression of ACACA mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in decreased expression of ACACA mRNA]		 CTD PMID:32652086 NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457 		JBrowse link
G Acox1 acyl-CoA oxidase 1 multiple interactions EXP [olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased activity of ACOX1 protein; [olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased expression of ACOX1 mRNA CTD PMID:23226405 NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I affects expression ISO olanzapine affects the expression of ADCYAP1R1 mRNA CTD PMID:27900577 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression
decreases expression
multiple interactions		 ISO olanzapine results in increased expression of ADIPOQ mRNA
Olanzapine results in decreased expression of ADIPOQ protein
capsazepine inhibits the reaction [Olanzapine results in decreased expression of ADIPOQ protein]; Metformin inhibits the reaction [Olanzapine results in decreased expression of ADIPOQ protein]; Ruthenium Red inhibits the reaction [Olanzapine results in decreased expression of ADIPOQ protein]		 CTD PMID:17651982 PMID:32652086 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Afm afamin affects phosphorylation ISO olanzapine affects the phosphorylation of AFM protein CTD PMID:25821032 NCBI chr14:17,531,022...17,563,868
Ensembl chr14:17,531,024...17,563,870 		JBrowse link
G Agrp agouti related neuropeptide increases expression
multiple interactions		 EXP
ISO		 olanzapine results in increased expression of AGRP protein
Metformin inhibits the reaction [Olanzapine results in increased expression of AGRP mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of AGRP mRNA]		 CTD PMID:21695181 PMID:32652086 NCBI chr19:33,447,992...33,481,602
Ensembl chr19:33,447,992...33,449,584 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases expression
decreases expression
multiple interactions
increases response to substance
increases phosphorylation		 ISO Olanzapine results in increased expression of AKT1 mRNA; Olanzapine results in increased expression of AKT1 protein
Olanzapine results in decreased expression of AKT1 mRNA
capsazepine inhibits the reaction [Olanzapine results in decreased expression of AKT1 mRNA]; Metformin inhibits the reaction [Olanzapine results in decreased expression of AKT1 mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in decreased expression of AKT1 mRNA]
AKT1 gene SNP results in increased susceptibility to olanzapine
olanzapine results in increased phosphorylation of AKT1 protein		 CTD PMID:19440698 PMID:21187413 PMID:32652086 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin affects phosphorylation ISO olanzapine affects the phosphorylation of ALB protein CTD PMID:25821032 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Apoa1 apolipoprotein A1 increases phosphorylation ISO olanzapine results in increased phosphorylation of APOA1 protein CTD PMID:25821032 NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G Apoa4 apolipoprotein A4 affects phosphorylation ISO olanzapine affects the phosphorylation of APOA4 protein CTD PMID:25821032 NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469 		JBrowse link
G Apob apolipoprotein B increases phosphorylation ISO olanzapine results in increased phosphorylation of APOB protein CTD PMID:25821032 NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497 		JBrowse link
G Apoc3 apolipoprotein C3 affects response to substance EXP APOC3 gene polymorphism affects the susceptibility to olanzapine CTD PMID:17726453 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583 		JBrowse link
G Apoh apolipoprotein H affects phosphorylation ISO olanzapine affects the phosphorylation of APOH protein CTD PMID:25821032 NCBI chr10:93,342,435...93,356,334
Ensembl chr10:93,310,977...93,356,329 		JBrowse link
G App amyloid beta precursor protein multiple interactions EXP olanzapine inhibits the reaction [APP protein modified form affects the activity of CAT protein]; olanzapine inhibits the reaction [APP protein modified form results in increased abundance of Reactive Oxygen Species] CTD PMID:15948179 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Aqp4 aquaporin 4 affects response to substance
increases response to substance		 ISO AQP4 gene polymorphism affects the susceptibility to olanzapine
AQP4 protein results in increased susceptibility to olanzapine		 CTD PMID:22544010 NCBI chr18:6,507,903...6,524,558
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP olanzapine results in increased expression of BAX protein CTD PMID:16462815 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression		 EXP olanzapine inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]
olanzapine results in increased expression of BCL2 mRNA; olanzapine results in increased expression of BCL2 protein		 CTD PMID:15126120 PMID:15276877 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP
ISO		 olanzapine results in increased expression of BDNF mRNA; olanzapine results in increased expression of BDNF protein
Olanzapine results in increased expression of BDNF mRNA; Olanzapine results in increased expression of BDNF protein		 CTD PMID:12478621 PMID:17442489 PMID:29182611 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Bik BCL2-interacting killer increases expression ISO olanzapine results in increased expression of BIK mRNA CTD PMID:16160616 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G C3 complement C3 affects phosphorylation ISO olanzapine affects the phosphorylation of C3 protein CTD PMID:25821032 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C4a complement C4A decreases phosphorylation ISO olanzapine results in decreased phosphorylation of C4A protein CTD PMID:25821032 NCBI chr20:4,005,731...4,020,083
Ensembl chr20:4,005,731...4,020,080 		JBrowse link
G C4b complement C4B affects phosphorylation ISO olanzapine affects the phosphorylation of C4B protein CTD PMID:25821032 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681 		JBrowse link
G C5 complement C5 affects phosphorylation ISO olanzapine affects the phosphorylation of C5 protein CTD PMID:25821032 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G C6 complement C6 affects phosphorylation ISO olanzapine affects the phosphorylation of C6 protein CTD PMID:25821032 NCBI chr 2:53,846,028...53,921,279
Ensembl chr 2:53,851,985...53,921,275 		JBrowse link
G C9 complement C9 affects phosphorylation ISO olanzapine affects the phosphorylation of C9 protein CTD PMID:25821032 NCBI chr 2:55,573,094...55,621,345
Ensembl chr 2:55,572,992...55,621,338 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP olanzapine results in decreased expression of and results in decreased phosphorylation of CAMK2A protein CTD PMID:18061412 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Cat catalase multiple interactions EXP olanzapine inhibits the reaction [APP protein modified form affects the activity of CAT protein] CTD PMID:15948179 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cfb complement factor B affects phosphorylation ISO olanzapine affects the phosphorylation of CFB protein CTD PMID:25821032 NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505 		JBrowse link
G Cfh complement factor H decreases phosphorylation ISO olanzapine results in decreased phosphorylation of CFH protein CTD PMID:25821032 NCBI chr13:51,512,376...51,613,829
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 affects binding ISO olanzapine binds to CHRM1 protein CTD PMID:16983399 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Clu clusterin affects phosphorylation ISO olanzapine affects the phosphorylation of CLU protein CTD PMID:25821032 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases phosphorylation ISO olanzapine results in decreased phosphorylation of COL1A1 protein CTD PMID:25821032 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP olanzapine results in increased expression of COMT mRNA CTD PMID:15964593 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Cp ceruloplasmin affects phosphorylation ISO olanzapine affects the phosphorylation of CP protein CTD PMID:25821032 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cpt2 carnitine palmitoyltransferase 2 multiple interactions EXP [olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in decreased expression of CPT2 mRNA; [olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased activity of CPT2 protein; [olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in increased expression of CPT2 mRNA CTD PMID:23226405 NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095 		JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP [Fluoxetine co-treated with olanzapine] results in decreased phosphorylation of CREB1 protein CTD PMID:14556240 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
increases expression
multiple interactions		 ISO olanzapine results in decreased expression of CTNNB1 mRNA
Olanzapine results in increased expression of CTNNB1 mRNA
Olanzapine inhibits the reaction [Dizocilpine Maleate results in decreased expression of CTNNB1 mRNA]		 CTD PMID:18797397 PMID:31563592 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects metabolic processing
multiple interactions		 ISO CYP1A2 protein affects the metabolism of olanzapine
Fluvoxamine inhibits the reaction [CYP1A2 protein affects the metabolism of olanzapine]		 CTD PMID:15545309 PMID:15883149 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Dab1 DAB adaptor protein 1 decreases expression EXP olanzapine results in decreased expression of DAB1 protein CTD PMID:19359144 NCBI chr 5:118,392,953...119,513,625
Ensembl chr 5:119,140,533...119,510,552 		JBrowse link
G Dclk1 doublecortin-like kinase 1 increases expression ISO olanzapine results in increased expression of DCLK1 mRNA CTD PMID:18797397 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956 		JBrowse link
G Drd1 dopamine receptor D1 affects binding ISO olanzapine binds to DRD1 protein CTD PMID:24389121 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 increases response to substance
affects binding
multiple interactions
decreases activity
affects activity		 ISO
EXP		 DRD2 gene SNP results in increased susceptibility to olanzapine; DRD2 intron SNP results in increased susceptibility to olanzapine
olanzapine binds to DRD2 protein
olanzapine promotes the reaction [Dopamine binds to DRD2 protein]
olanzapine results in decreased activity of DRD2 protein
olanzapine affects the activity of DRD2 protein		 CTD PMID:10482380 PMID:10831489 PMID:11198054 PMID:15716360 PMID:20361897 More... NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 multiple interactions ISO DRD3 protein results in increased susceptibility to [olanzapine co-treated with Fluoxetine] CTD PMID:20021991 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G F2 coagulation factor II, thrombin affects phosphorylation ISO olanzapine affects the phosphorylation of F2 protein CTD PMID:25821032 NCBI chr 3:77,596,196...77,609,486
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Olanzapine results in increased expression of FABP1 mRNA CTD PMID:31437515 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fasn fatty acid synthase increases expression ISO olanzapine results in increased expression of FASN mRNA CTD PMID:17651982 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261 		JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions EXP [Fluoxetine co-treated with olanzapine] results in increased expression of FGF2 mRNA CTD PMID:15158429 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fn1 fibronectin 1 affects phosphorylation ISO olanzapine affects the phosphorylation of FN1 protein CTD PMID:25821032 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Fluoxetine co-treated with olanzapine] results in decreased expression of FOS protein CTD PMID:14556240 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions EXP olanzapine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of FOSL1 protein] CTD PMID:11425506 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Gad1 glutamate decarboxylase 1 decreases expression EXP olanzapine results in decreased expression of GAD1 mRNA; olanzapine results in decreased expression of GAD1 protein CTD PMID:14519413 PMID:19359144 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gad2 glutamate decarboxylase 2 decreases expression EXP olanzapine results in decreased expression of GAD2 protein CTD PMID:19359144 NCBI chr17:84,763,630...84,826,155
Ensembl chr17:84,763,628...84,826,155 		JBrowse link
G Gc GC, vitamin D binding protein affects phosphorylation ISO olanzapine affects the phosphorylation of GC protein CTD PMID:25821032 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Olanzapine results in increased expression of GCLC mRNA CTD PMID:37005277 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions
increases expression		 ISO capsazepine inhibits the reaction [Olanzapine results in increased expression of GFAP mRNA]; Metformin inhibits the reaction [Olanzapine results in increased expression of GFAP mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of GFAP mRNA] CTD PMID:32652086 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Ghrl ghrelin and obestatin prepropeptide multiple interactions
increases expression		 ISO capsazepine inhibits the reaction [Olanzapine results in increased expression of GHRL protein]; Metformin inhibits the reaction [Olanzapine results in increased expression of GHRL protein]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of GHRL protein] CTD PMID:32652086 NCBI chr 4:146,865,712...146,869,621
Ensembl chr 4:146,865,712...146,869,621 		JBrowse link
G Ghsr growth hormone secretagogue receptor increases expression
multiple interactions		 ISO Olanzapine results in increased expression of GHSR mRNA
capsazepine inhibits the reaction [Olanzapine results in increased expression of GHSR mRNA]; Metformin inhibits the reaction [Olanzapine results in increased expression of GHSR mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of GHSR mRNA]		 CTD PMID:32652086 NCBI chr 2:110,268,489...110,271,865
Ensembl chr 2:110,268,489...110,271,865 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions
increases expression		 ISO Dietary Fats promotes the reaction [Olanzapine results in increased expression of GPT protein] CTD PMID:37019375 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 increases expression EXP olanzapine results in increased expression of GRIA2 mRNA CTD PMID:11526992 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 increases expression EXP olanzapine results in increased expression of GRIA3 mRNA CTD PMID:11526992 NCBI chr  X:120,238,515...120,504,106
Ensembl chr  X:120,238,534...120,504,096 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions
decreases expression		 ISO olanzapine results in increased phosphorylation of GSK3B protein
Olanzapine inhibits the reaction [Dizocilpine Maleate results in increased expression of GSK3B mRNA]
Olanzapine results in decreased expression of GSK3B mRNA		 CTD PMID:19440698 PMID:31563592 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression
decreases expression
multiple interactions		 ISO
EXP		 olanzapine results in increased expression of HMGCR mRNA
olanzapine results in decreased expression of HMGCR mRNA
1-(carboxymethylthio)tetradecane promotes the reaction [olanzapine results in decreased expression of HMGCR mRNA]; olanzapine promotes the reaction [1-(carboxymethylthio)tetradecane results in decreased expression of HMGCR mRNA]		 CTD PMID:17052361 PMID:23226405 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO olanzapine results in increased expression of HMGCS1 mRNA CTD PMID:17052361 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Olanzapine results in increased expression of HMOX1 mRNA CTD PMID:37005277 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hpx hemopexin affects phosphorylation ISO olanzapine affects the phosphorylation of HPX protein CTD PMID:25821032 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Hrg histidine-rich glycoprotein affects phosphorylation ISO olanzapine affects the phosphorylation of HRG protein CTD PMID:25821032 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrh1 histamine receptor H 1 affects binding
multiple interactions		 ISO olanzapine binds to HRH1 protein
HRH1 protein results in increased susceptibility to [olanzapine co-treated with Fluoxetine]		 CTD PMID:16983399 PMID:20021991 PMID:24389121 NCBI chr 4:147,564,963...147,649,353
Ensembl chr 4:147,645,995...147,647,455 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
affects binding
decreases activity		 ISO
EXP		 olanzapine binds to and results in decreased activity of HTR2A protein
olanzapine binds to HTR2A protein
olanzapine results in decreased activity of HTR2A protein
[[olanzapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein; [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [olanzapine results in decreased activity of HTR2A protein]; [olanzapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein; olanzapine binds to and results in decreased activity of HTR2A protein		 CTD PMID:16983399 PMID:18976543 PMID:19304867 PMID:20521326 PMID:24389121 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C increases response to substance
affects binding
affects response to substance		 ISO HTR2C gene polymorphism results in increased susceptibility to olanzapine
olanzapine binds to HTR2C protein
HTR2C gene polymorphism affects the susceptibility to Olanzapine; HTR2C gene SNP affects the susceptibility to Olanzapine; HTR2C protein affects the susceptibility to Olanzapine		 CTD PMID:15666332 PMID:16983399 PMID:19142110 PMID:19434072 PMID:24389121 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 affects binding ISO olanzapine binds to HTR6 protein CTD PMID:16983399 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Il10 interleukin 10 increases expression
decreases expression
multiple interactions		 ISO Olanzapine results in increased expression of IL10 mRNA
Olanzapine results in decreased expression of IL10 protein
Lithium inhibits the reaction [Olanzapine results in decreased expression of IL10 protein]		 CTD PMID:30695037 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 ISO Lithium inhibits the reaction [Olanzapine results in increased expression of IL1B mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL1B protein]
Olanzapine results in increased expression of IL1B mRNA; Olanzapine results in increased expression of IL1B protein		 CTD PMID:30695037 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions
increases expression		 ISO capsazepine inhibits the reaction [Olanzapine results in increased expression of IL6 protein]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL6 mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of IL6 protein]; Metformin inhibits the reaction [Olanzapine results in increased expression of IL6 protein]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of IL6 protein]
Olanzapine results in increased expression of IL6 mRNA; Olanzapine results in increased expression of IL6 protein		 CTD PMID:30695037 PMID:32652086 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 increases secretion
increases expression		 ISO olanzapine results in increased secretion of INS protein
olanzapine results in increased expression of INS protein		 CTD PMID:11769361 PMID:11927762 PMID:16601995 PMID:19512971 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Itih2 inter-alpha-trypsin inhibitor heavy chain 2 affects phosphorylation ISO olanzapine affects the phosphorylation of ITIH2 protein CTD PMID:25821032 NCBI chr17:68,375,574...68,411,849
Ensembl chr17:68,375,567...68,411,841 		JBrowse link
G Itih4 inter-alpha-trypsin inhibitor heavy chain 4 affects phosphorylation ISO olanzapine affects the phosphorylation of ITIH4 protein CTD PMID:25821032 NCBI chr16:6,080,539...6,095,710
Ensembl chr16:6,080,539...6,095,708 		JBrowse link
G Jak2 Janus kinase 2 multiple interactions
increases activity		 EXP [[olanzapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein; [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [olanzapine results in decreased activity of HTR2A protein]; [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [olanzapine results in increased expression of RGS7 mRNA]; [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [olanzapine results in increased expression of RGS7 protein]; [olanzapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein
olanzapine results in increased activity of JAK2 protein		 CTD PMID:18976543 PMID:19304867 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189 		JBrowse link
G Kcna1 potassium voltage-gated channel subfamily A member 1 increases expression ISO olanzapine results in increased expression of KCNA1 mRNA CTD PMID:18797397 NCBI chr 4:159,464,223...159,472,905
Ensembl chr 4:159,464,188...159,472,682 		JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 decreases expression ISO olanzapine results in decreased expression of KCNAB1 mRNA CTD PMID:18797397 NCBI chr 2:149,137,025...149,603,540
Ensembl chr 2:149,137,041...149,603,534 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions		 ISO olanzapine results in decreased activity of KCNH2 protein
olanzapine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]		 CTD PMID:16494862 PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnip3 potassium voltage-gated channel interacting protein 3 decreases expression ISO olanzapine results in decreased expression of KCNIP3 mRNA; olanzapine results in decreased expression of KCNIP3 protein CTD PMID:18797397 NCBI chr 3:114,677,027...114,742,923
Ensembl chr 3:114,677,030...114,743,556 		JBrowse link
G Klc1 kinesin light chain 1 decreases expression ISO olanzapine results in decreased expression of KLC1 mRNA CTD PMID:18797397 NCBI chr 6:130,823,416...130,866,729
Ensembl chr 6:130,823,419...130,867,031 		JBrowse link
G Kng1 kininogen 1 affects phosphorylation ISO Olanzapine affects the phosphorylation of KNG1 protein CTD PMID:25821032 NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555 		JBrowse link
G Ldlr low density lipoprotein receptor increases expression
multiple interactions		 ISO olanzapine results in increased expression of LDLR mRNA
olanzapine promotes the reaction [SREBF1 protein results in increased expression of LDLR mRNA]		 CTD PMID:17052361 PMID:17651982 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Lep leptin increases expression
multiple interactions		 ISO olanzapine results in increased expression of LEP protein
Olanzapine results in increased expression of LEP protein
capsazepine inhibits the reaction [Olanzapine results in increased expression of LEP protein]; Metformin inhibits the reaction [Olanzapine results in increased expression of LEP protein]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of LEP protein]		 CTD PMID:11927762 PMID:19512971 PMID:32652086 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Mal mal, T-cell differentiation protein decreases expression ISO olanzapine results in decreased expression of MAL mRNA CTD PMID:18797397 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Maoa monoamine oxidase A increases expression EXP olanzapine results in increased expression of MAOA mRNA CTD PMID:15964593 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Maob monoamine oxidase B increases expression EXP olanzapine results in increased expression of MAOB mRNA CTD PMID:15964593 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP olanzapine results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase affects response to substance ISO MTHFR gene polymorphism affects the susceptibility to olanzapine; MTHFR protein affects the susceptibility to olanzapine CTD PMID:20547447 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Ncan neurocan decreases expression ISO olanzapine results in decreased expression of NCAN mRNA CTD PMID:18797397 NCBI chr16:19,301,969...19,328,436
Ensembl chr16:19,301,969...19,328,436 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase decreases expression ISO olanzapine results in decreased expression of NEDD4 mRNA; olanzapine results in decreased expression of NEDD4 protein CTD PMID:18797397 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases expression ISO Olanzapine results in decreased expression of NFE2L2 protein CTD PMID:37019375 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions
increases expression		 ISO capsazepine inhibits the reaction [Olanzapine results in increased expression of NFKB1 mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of NFKB1 mRNA] CTD PMID:32652086 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nptn neuroplastin increases expression ISO olanzapine results in increased expression of NPTN mRNA CTD PMID:18797397 NCBI chr 8:58,996,873...59,063,402
Ensembl chr 8:58,996,887...59,063,401 		JBrowse link
G Npy neuropeptide Y decreases expression
increases expression
multiple interactions		 EXP
ISO		 olanzapine results in decreased expression of NPY mRNA
Olanzapine results in increased expression of NPY mRNA
capsazepine inhibits the reaction [Olanzapine results in increased expression of NPY mRNA]; Metformin inhibits the reaction [Olanzapine results in increased expression of NPY mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of NPY mRNA]
olanzapine results in increased expression of NPY protein		 CTD PMID:16516965 PMID:21695181 PMID:32652086 NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Numbl NUMB-like, endocytic adaptor protein decreases expression ISO olanzapine results in decreased expression of NUMBL mRNA CTD PMID:18797397 NCBI chr 1:82,549,814...82,573,788
Ensembl chr 1:82,550,054...82,573,776 		JBrowse link
G Pde1a phosphodiesterase 1A increases expression EXP olanzapine results in increased expression of PDE1A mRNA CTD PMID:20222156 NCBI chr 3:64,745,140...65,025,178
Ensembl chr 3:64,747,269...65,024,874 		JBrowse link
G Pde8b phosphodiesterase 8B increases expression EXP olanzapine results in increased expression of PDE8B mRNA CTD PMID:20222156 NCBI chr 2:26,275,117...26,479,725
Ensembl chr 2:26,276,635...26,509,209 		JBrowse link
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 multiple interactions
decreases expression		 ISO capsazepine inhibits the reaction [Olanzapine results in decreased expression of PIK3R1 mRNA]; Metformin inhibits the reaction [Olanzapine results in decreased expression of PIK3R1 mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in decreased expression of PIK3R1 mRNA] CTD PMID:32652086 NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631 		JBrowse link
G Plac8 placenta associated 8 affects phosphorylation ISO olanzapine affects the phosphorylation of C15 protein CTD PMID:25821032 NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264 		JBrowse link
G Plp1 proteolipid protein 1 decreases expression ISO olanzapine results in decreased expression of PLP1 mRNA CTD PMID:18797397 NCBI chr  X:100,184,039...100,201,035
Ensembl chr  X:100,185,767...100,201,032 		JBrowse link
G Pnpla2 patatin-like phospholipase domain containing 2 affects expression EXP olanzapine affects the expression of PNPLA2 mRNA CTD PMID:23226405 NCBI chr 1:196,552,723...196,557,805
Ensembl chr 1:196,552,723...196,557,805 		JBrowse link
G Pomc proopiomelanocortin decreases expression
multiple interactions		 EXP
ISO		 olanzapine results in decreased expression of POMC protein
Olanzapine results in decreased expression of POMC mRNA
capsazepine inhibits the reaction [Olanzapine results in decreased expression of POMC mRNA]; Metformin inhibits the reaction [Olanzapine results in decreased expression of POMC mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in decreased expression of POMC mRNA]		 CTD PMID:21695181 PMID:32652086 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression ISO olanzapine results in increased expression of PPARG protein alternative form CTD PMID:17651982 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha decreases expression
multiple interactions		 EXP olanzapine results in decreased expression of PPARGC1A mRNA
[olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in decreased expression of PPARGC1A mRNA; olanzapine promotes the reaction [1-(carboxymethylthio)tetradecane results in decreased expression of PPARGC1A mRNA]		 CTD PMID:23226405 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Prkag2 protein kinase AMP-activated non-catalytic subunit gamma 2 increases expression
multiple interactions		 ISO Olanzapine results in increased expression of PRKAG2 mRNA
capsazepine inhibits the reaction [Olanzapine results in increased expression of PRKAG2 mRNA]; Metformin inhibits the reaction [Olanzapine results in increased expression of PRKAG2 mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of PRKAG2 mRNA]		 CTD PMID:32652086 NCBI chr 4:10,010,890...10,252,155
Ensembl chr 4:10,010,890...10,252,142 		JBrowse link
G Prl prolactin multiple interactions
increases secretion
increases expression		 ISO [olanzapine co-treated with Fluoxetine] results in increased expression of PRL protein
olanzapine results in increased secretion of PRL protein
olanzapine results in increased expression of PRL protein		 CTD PMID:9090331 PMID:9265911 PMID:9376336 PMID:10831029 PMID:11048906 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prrc2a proline-rich coiled-coil 2A decreases expression ISO olanzapine results in decreased expression of PRRC2A mRNA CTD PMID:18797397 NCBI chr20:3,658,391...3,674,143
Ensembl chr20:3,658,695...3,674,130 		JBrowse link
G Rapgef4 Rap guanine nucleotide exchange factor 4 decreases expression ISO olanzapine results in decreased expression of RAPGEF4 mRNA CTD PMID:18797397 NCBI chr 3:56,809,388...57,101,332
Ensembl chr 3:56,809,270...57,102,316 		JBrowse link
G Reln reelin increases expression EXP olanzapine results in increased expression of RELN mRNA; olanzapine results in increased expression of RELN protein CTD PMID:19359144 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 multiple interactions
increases expression		 EXP [[Olanzapine binds to and results in decreased activity of HTR2A protein] which results in increased phosphorylation of JAK2 protein] which results in increased expression of RGS7 protein; [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [Olanzapine results in increased expression of RGS7 mRNA]; [alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide results in decreased activity of JAK2 protein] inhibits the reaction [Olanzapine results in increased expression of RGS7 protein]; Olanzapine promotes the reaction [[STAT3 protein binds to RGS7 promoter] which results in increased expression of RGS7 mRNA]; Olanzapine promotes the reaction [STAT3 protein binds to RGS7 promoter]
olanzapine results in increased expression of RGS7 mRNA; olanzapine results in increased expression of RGS7 protein		 CTD PMID:18976543 PMID:19304867 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rtn4 reticulon 4 decreases expression ISO olanzapine results in decreased expression of RTN4 mRNA CTD PMID:18797397 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO olanzapine results in decreased expression of S100A9 mRNA CTD PMID:18797397 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO olanzapine results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N increases phosphorylation ISO Olanzapine results in increased phosphorylation of SERPINA3 protein CTD PMID:25821032 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serping1 serpin family G member 1 affects phosphorylation ISO olanzapine affects the phosphorylation of SERPING1 protein CTD PMID:25821032 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Serpini1 serpin family I member 1 decreases expression ISO olanzapine results in decreased expression of SERPINI1 mRNA CTD PMID:18797397 NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135 		JBrowse link
G Shbg sex hormone binding globulin decreases expression ISO olanzapine results in decreased expression of SHBG protein CTD PMID:19512971 NCBI chr10:54,332,939...54,350,409
Ensembl chr10:54,332,941...54,351,057 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO olanzapine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 decreases expression
multiple interactions		 ISO Olanzapine results in decreased expression of SLC22A5 mRNA; Olanzapine results in decreased expression of SLC22A5 protein
Olanzapine inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine analog]		 CTD PMID:31437515 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Slc27a2 solute carrier family 27 member 2 increases expression ISO Olanzapine results in increased expression of SLC27A2 mRNA CTD PMID:31437515 NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208 		JBrowse link
G Slc27a5 solute carrier family 27 member 5 increases expression ISO Olanzapine results in increased expression of SLC27A5 mRNA CTD PMID:31437515 NCBI chr 1:73,616,556...73,627,149
Ensembl chr 1:73,616,564...73,627,172 		JBrowse link
G Slc2a4 solute carrier family 2 member 4 increases expression ISO olanzapine results in increased expression of SLC2A4 mRNA CTD PMID:16002093 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565 		JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Olanzapine results in decreased expression of SLC7A11 mRNA CTD PMID:37005277 NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536 		JBrowse link
G Snap25 synaptosome associated protein 25 affects response to substance ISO SNAP25 gene SNP affects the susceptibility to olanzapine CTD PMID:15823421 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
decreases activity
increases expression		 EXP
ISO		 olanzapine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SOD1 mRNA]; olanzapine inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]; olanzapine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SOD1 mRNA]
Olanzapine results in decreased activity of SOD1 protein
Dietary Fats promotes the reaction [Olanzapine results in decreased activity of SOD1 protein]
olanzapine results in increased expression of SOD1 mRNA		 CTD PMID:12752374 PMID:12868070 PMID:16564057 PMID:37019375 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 ISO olanzapine promotes the reaction [SREBF1 protein results in increased expression of LDLR mRNA]; olanzapine results in increased activity of and results in increased expression of SREBF1 protein
olanzapine results in increased expression of SREBF1 mRNA		 CTD PMID:17651982 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 multiple interactions ISO
EXP		 olanzapine results in increased cleavage of and results in increased activity of SREBF2 protein
[olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in decreased expression of SREBF2 mRNA		 CTD PMID:17052361 PMID:23226405 NCBI chr 7:113,663,202...113,720,850
Ensembl chr 7:113,663,202...113,720,848 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP olanzapine promotes the reaction [[STAT3 protein binds to RGS7 promoter] which results in increased expression of RGS7 mRNA]; olanzapine promotes the reaction [STAT3 protein binds to RGS7 promoter] CTD PMID:18976543 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Sypl1 synaptophysin-like 1 decreases expression ISO Olanzapine results in decreased expression of SYPL1 mRNA CTD PMID:18797397 NCBI chr 6:49,565,111...49,585,205
Ensembl chr 6:49,565,154...49,585,330 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP olanzapine inhibits the reaction [Methamphetamine results in decreased expression of TH protein] CTD PMID:15276877 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression		 ISO capsazepine inhibits the reaction [Olanzapine results in increased expression of TNF protein]; Dietary Fats promotes the reaction [Olanzapine results in increased expression of TNF protein]; Lithium inhibits the reaction [Olanzapine results in increased expression of TNF mRNA]; Lithium inhibits the reaction [Olanzapine results in increased expression of TNF protein]; Metformin inhibits the reaction [Olanzapine results in increased expression of TNF protein]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of TNF protein]
Olanzapine results in increased expression of TNF mRNA; Olanzapine results in increased expression of TNF protein		 CTD PMID:30695037 PMID:32652086 PMID:37019375 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO olanzapine results in increased expression of TP53 mRNA CTD PMID:16160616 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions
increases expression		 ISO capsazepine inhibits the reaction [Olanzapine results in increased expression of TRPV1 mRNA]; Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of TRPV1 mRNA] CTD PMID:32652086 NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513 		JBrowse link
G Trpv3 transient receptor potential cation channel, subfamily V, member 3 multiple interactions
increases expression		 ISO Ruthenium Red inhibits the reaction [Olanzapine results in increased expression of TRPV3 mRNA] CTD PMID:32652086 NCBI chr10:57,883,546...57,915,865
Ensembl chr10:57,883,546...57,913,296 		JBrowse link
G Ttr transthyretin increases expression EXP olanzapine results in increased expression of TTR mRNA CTD PMID:15927202 NCBI chr18:11,941,791...11,951,008
Ensembl chr18:11,943,789...11,951,008 		JBrowse link
G Ucp1 uncoupling protein 1 multiple interactions EXP [olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in decreased expression of UCP1 mRNA CTD PMID:23226405 NCBI chr19:24,808,782...24,816,853
Ensembl chr19:24,808,783...24,816,852 		JBrowse link
G Vipr2 vasoactive intestinal peptide receptor 2 affects expression ISO olanzapine affects the expression of VIPR2 mRNA CTD PMID:27900577 NCBI chr 6:136,996,664...137,070,599
Ensembl chr 6:137,001,511...137,070,597 		JBrowse link
G Vldlr very low density lipoprotein receptor increases expression EXP olanzapine results in increased expression of VLDLR protein CTD PMID:19359144 NCBI chr 1:224,813,539...224,850,400
Ensembl chr 1:224,814,377...224,845,920 		JBrowse link
paliperidone palmitate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects abundance
multiple interactions
increases export
increases transport
affects response to substance
decreases activity		 ISO
EXP		 ABCB1 gene polymorphism affects the abundance of Paliperidone Palmitate; ABCB1 protein affects the abundance of Paliperidone Palmitate
Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of Paliperidone Palmitate]
ABCB1A protein results in increased transport of Paliperidone Palmitate
ABCB1A protein affects the susceptibility to Paliperidone Palmitate
Paliperidone Palmitate results in decreased activity of ABCB1 protein
Paliperidone Palmitate inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]
ABCB1 protein results in increased transport of Paliperidone Palmitate		 CTD PMID:15502009 PMID:16118767 PMID:16810505 PMID:16936711 PMID:17541883 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects response to substance ISO ABCB1B protein affects the susceptibility to Paliperidone Palmitate CTD PMID:15502009 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcb4 ATP binding cassette subfamily B member 4 decreases activity ISO Paliperidone Palmitate results in decreased activity of ABCB4 protein CTD PMID:28437613 NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Paliperidone Palmitate inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Paliperidone Palmitate results in increased expression of BDNF mRNA CTD PMID:21220416 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects abundance ISO CYP2D6 gene polymorphism affects the abundance of Paliperidone Palmitate; CYP2D6 protein affects the abundance of Paliperidone Palmitate CTD PMID:10639689 PMID:15089809 PMID:17541883 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects binding		 ISO
EXP		 Paliperidone Palmitate binds to and results in decreased activity of DRD2 protein
Paliperidone Palmitate binds to DRD2 protein		 CTD PMID:19713555 PMID:22437487 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Fads2 fatty acid desaturase 2 increases expression
multiple interactions		 EXP Paliperidone Palmitate results in increased expression of FADS2 mRNA
[Paliperidone Palmitate results in increased expression of FADS2 mRNA] which results in increased abundance of Fatty Acids, Unsaturated		 CTD PMID:21458237 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A affects binding
multiple interactions		 ISO
EXP		 Paliperidone Palmitate binds to HTR2A protein
Paliperidone Palmitate binds to and results in decreased activity of HTR2A protein		 CTD PMID:7520908 PMID:19713555 PMID:22437487 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Paliperidone Palmitate binds to and results in decreased activity of HTR7 protein CTD PMID:18996971 PMID:19509219 PMID:20827463 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Il1a interleukin 1 alpha increases expression ISO Paliperidone Palmitate results in increased expression of IL1A mRNA CTD PMID:32816093 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO Paliperidone Palmitate results in increased expression of IL1B mRNA CTD PMID:32816093 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il24 interleukin 24 increases expression ISO Paliperidone Palmitate results in increased expression of IL24 mRNA CTD PMID:32816093 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Paliperidone Palmitate results in decreased activity of KCNH2 protein CTD PMID:21394035 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Prl prolactin increases expression ISO Paliperidone Palmitate results in increased expression of PRL protein CTD PMID:17460786 PMID:19825908 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
perazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases methylation ISO CYP3A4 protein results in decreased methylation of Perazine CTD PMID:11026737 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 increases oxidation ISO FMO3 protein results in increased oxidation of Perazine CTD PMID:11026737 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
periciazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions ISO periciazine binds to and results in decreased activity of AR protein CTD PMID:17606915 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO periciazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
perphenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ces1d carboxylesterase 1D multiple interactions ISO Perphenazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Perphenazine inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO
EXP		 Perphenazine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein] CTD PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Fshb follicle stimulating hormone subunit beta decreases expression EXP Perphenazine results in decreased expression of FSHB protein CTD PMID:6770916 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Perphenazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Perphenazine results in decreased activity of KCNH2 protein		 CTD PMID:21158687 PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression EXP Perphenazine results in decreased expression of LHB protein CTD PMID:6770916 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Prl prolactin increases expression ISO
EXP		 Perphenazine results in increased expression of PRL protein CTD PMID:6770916 PMID:7262630 PMID:17335319 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Perphenazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Tnni3 troponin I3, cardiac type increases expression ISO Perphenazine results in increased expression of TNNI3 protein CTD PMID:14742781 NCBI chr 1:69,299,900...69,303,582
Ensembl chr 1:69,299,900...69,303,580 		JBrowse link
pimozide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Pimozide results in decreased expression of BCL2 mRNA CTD PMID:12130671 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP istradefylline inhibits the reaction [Pimozide results in increased expression of FOS protein]; Tropicamide promotes the reaction [Pimozide results in increased expression of FOS protein] CTD PMID:19467297 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Kcna10 potassium voltage-gated channel subfamily A member 10 multiple interactions ISO Pimozide inhibits the reaction [KCNA10 protein results in increased transport of Potassium] CTD PMID:10836990 NCBI chr 2:194,786,500...194,798,575
Ensembl chr 2:194,786,500...194,798,575 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Pimozide inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Pimozide results in decreased activity of KCNH2 protein		 CTD PMID:15671647 PMID:19583963 PMID:21158687 PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions EXP Pimozide results in decreased secretion of and results in decreased glycosylation of LHB protein CTD PMID:3896764 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Prl prolactin increases expression ISO Pimozide results in increased expression of PRL protein CTD PMID:8915564 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
prochlorperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase increases activity ISO Prochlorperazine results in increased activity of ACHE protein CTD PMID:29614332 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Prochlorperazine binds to and results in increased activity of ESR1 protein CTD PMID:25752796 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Tfeb transcription factor EB affects localization ISO Prochlorperazine affects the localization of TFEB protein CTD PMID:28366621 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714 		JBrowse link
promazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bche butyrylcholinesterase decreases activity ISO Promazine results in decreased activity of BCHE protein CTD PMID:236606 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148 		JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Promazine results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Promazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Promazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
quetiapine fumarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO Quetiapine Fumarate results in decreased activity of ABCB1 protein CTD PMID:16810505 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Quetiapine Fumarate inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone] CTD PMID:18834354 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G App amyloid beta precursor protein multiple interactions EXP Quetiapine Fumarate inhibits the reaction [APP protein modified form affects the activity of CAT protein]; Quetiapine Fumarate inhibits the reaction [APP protein modified form results in increased abundance of Reactive Oxygen Species] CTD PMID:15948179 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Quetiapine Fumarate results in increased expression of BAX protein CTD PMID:16462815 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP Quetiapine Fumarate results in increased expression of BDNF protein CTD PMID:17442489 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Cat catalase multiple interactions EXP Quetiapine Fumarate inhibits the reaction [APP protein modified form affects the activity of CAT protein] CTD PMID:15948179 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression ISO Quetiapine Fumarate results in decreased expression of CNR1 protein CTD PMID:31220554 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression ISO Quetiapine Fumarate results in increased expression of CNR2 protein CTD PMID:31220554 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO Carbamazepine promotes the reaction [CYP3A4 protein results in increased metabolism of and results in decreased abundance of Quetiapine Fumarate]; CYP3A4 protein results in increased metabolism of and results in decreased abundance of Quetiapine Fumarate; Ketoconazole inhibits the reaction [CYP3A4 protein results in increased metabolism of and results in decreased abundance of Quetiapine Fumarate] CTD PMID:16390352 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions EXP Quetiapine Fumarate promotes the reaction [Dopamine binds to DRD2 protein] CTD PMID:15716360 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO Quetiapine Fumarate inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:16314884 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Quetiapine Fumarate inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Quetiapine Fumarate results in decreased activity of KCNH2 protein		 CTD PMID:21158687 PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta decreases metabolic processing ISO Quetiapine Fumarate results in decreased metabolism of MAP1LC3B protein CTD PMID:31220554 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Mbp myelin basic protein multiple interactions ISO Quetiapine Fumarate inhibits the reaction [Cuprizone results in decreased activity of MBP protein] CTD PMID:18938062 NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404 		JBrowse link
G Mlkl mixed lineage kinase domain like pseudokinase multiple interactions ISO 1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; 1,1-dimethylbutyl-1-deoxy-Delta(9)-THC inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein]; AM 1241 inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; AM 1241 inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein]; AM 281 inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; AM 281 inhibits the reaction [Quetiapine Fumarate results in increased phosphorylation of MLKL protein]; Quetiapine Fumarate results in increased expression of and affects the localization of MLKL protein; Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein; Rimonabant inhibits the reaction [Quetiapine Fumarate affects the localization of MLKL protein]; Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of and results in increased phosphorylation of MLKL protein] CTD PMID:31220554 NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502 		JBrowse link
G Mpo myeloperoxidase multiple interactions
decreases activity
affects oxidation		 ISO Quetiapine Fumarate inhibits the reaction [[MPO protein results in increased metabolism of chlorodimedone] which results in increased abundance of Hypochlorous Acid]; Quetiapine Fumarate inhibits the reaction [MPO protein results in increased abundance of Hypochlorous Acid]
Quetiapine Fumarate results in decreased activity of MPO protein
MPO protein affects the oxidation of Quetiapine Fumarate		 CTD PMID:35575633 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 increases expression EXP Quetiapine Fumarate results in increased expression of NDUFV2 mRNA CTD PMID:19441803 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713 		JBrowse link
G Ngfr nerve growth factor receptor decreases expression EXP Quetiapine Fumarate results in decreased expression of NGFR mRNA CTD PMID:12111809 PMID:16513140 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Prl prolactin decreases expression
increases secretion		 ISO Quetiapine Fumarate results in decreased expression of PRL protein
Quetiapine Fumarate results in increased secretion of PRL protein		 CTD PMID:16379509 PMID:18063941 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions
increases expression		 ISO AM 281 inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK1 protein]; Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK1 protein] CTD PMID:31220554 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 multiple interactions
increases expression		 ISO Rimonabant inhibits the reaction [Quetiapine Fumarate results in increased expression of RIPK3 protein] CTD PMID:31220554 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO Quetiapine Fumarate inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] CTD PMID:30465787 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression		 ISO
EXP		 Quetiapine Fumarate inhibits the reaction [Cuprizone results in decreased activity of SOD1 protein]
Quetiapine Fumarate results in increased expression of SOD1 mRNA
Quetiapine Fumarate inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SOD1 mRNA]		 CTD PMID:12111809 PMID:12752374 PMID:18938062 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
reserpine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity		 ISO Reserpine inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
Reserpine results in decreased activity of ABCB11 protein		 CTD PMID:20829430 PMID:23956101 PMID:24014644 NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases expression
decreases activity		 ISO Cycloheximide promotes the reaction [Reserpine results in increased expression of ABCB1 mRNA]; Reserpine inhibits the reaction [ABCB1 protein affects the export of calcein AM]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of fluorexon]; Reserpine inhibits the reaction [ABCB1 protein results in increased secretion of Vinblastine]
Reserpine inhibits the reaction [ABCB1A protein results in increased secretion of fluorexon]
Reserpine results in increased expression of ABCB1 mRNA; Reserpine results in increased expression of ABCB1 protein
Reserpine results in decreased activity of ABCB1 protein		 CTD PMID:7476894 PMID:8632764 PMID:10617675 PMID:12235267 PMID:19528478 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Reserpine inhibits the reaction [ABCG2 protein results in increased transport of Irinotecan] CTD PMID:12869632 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Ache acetylcholinesterase multiple interactions
affects activity		 EXP [Plant Extracts results in increased abundance of Dronabinol] inhibits the reaction [Reserpine affects the activity of ACHE protein] CTD PMID:28212939 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Adra1d adrenoceptor alpha 1D increases response to substance
increases expression		 EXP ADRA1D protein results in increased susceptibility to Reserpine
Reserpine results in increased expression of ADRA1D mRNA		 CTD PMID:15159276 PMID:17676312 NCBI chr 3:118,793,356...118,809,354
Ensembl chr 3:118,793,346...118,809,354 		JBrowse link
G Adra2a adrenoceptor alpha 2A increases expression EXP Reserpine results in increased expression of ADRA2A mRNA CTD PMID:11264240 NCBI chr 1:253,061,480...253,064,280
Ensembl chr 1:253,060,218...253,064,365 		JBrowse link
G Adrb1 adrenoceptor beta 1 increases expression
increases stability		 EXP Reserpine results in increased expression of ADRB1 mRNA; Reserpine results in increased expression of ADRB1 protein
Reserpine results in increased stability of ADRB1 mRNA		 CTD PMID:1336118 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Adrb2 adrenoceptor beta 2 increases expression EXP Reserpine results in increased expression of ADRB2 mRNA CTD PMID:1664493 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 increases expression EXP Reserpine results in increased expression of AGTR2 mRNA; Reserpine results in increased expression of AGTR2 protein CTD PMID:20964730 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Reserpine results in increased expression of AKR1B10 mRNA CTD PMID:26198647 NCBI chr 4:63,038,459...63,060,336
Ensembl chr 4:63,040,169...63,053,852 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions		 ISO Reserpine results in decreased phosphorylation of AKT1 protein
arsenic trioxide promotes the reaction [Reserpine results in decreased phosphorylation of AKT1 protein]		 CTD PMID:26114099 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Amd1 adenosylmethionine decarboxylase 1 multiple interactions ISO Reserpine inhibits the reaction [Folic Acid results in increased activity of AMD1 protein] CTD PMID:17371283 NCBI chr20:43,695,783...43,711,476
Ensembl chr20:43,697,237...43,711,476 		JBrowse link
G Ar androgen receptor multiple interactions ISO Reserpine inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein] CTD PMID:29162470 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Arc activity-regulated cytoskeleton-associated protein multiple interactions EXP Reserpine inhibits the reaction [Cocaine results in increased expression of ARC mRNA] CTD PMID:7722525 NCBI chr 7:106,555,968...106,559,697
Ensembl chr 7:106,555,785...106,559,378 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 EXP IAPP protein inhibits the reaction [Reserpine results in increased expression of BAX protein] CTD PMID:19463876 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression		 EXP IAPP protein inhibits the reaction [Reserpine results in decreased expression of BCL2 protein] CTD PMID:19463876 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions		 ISO
EXP		 Reserpine results in decreased expression of BDNF protein
cerebrolysin inhibits the reaction [Reserpine results in decreased expression of BDNF protein]; Fluoxetine inhibits the reaction [Reserpine results in decreased expression of BDNF protein]
arsenic trioxide promotes the reaction [Reserpine results in decreased expression of BDNF protein]		 CTD PMID:26114099 PMID:33279466 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 affects binding ISO Reserpine binds to BIRC5 promoter CTD PMID:17968851 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G C3 complement C3 affects expression EXP Reserpine affects the expression of C3 mRNA CTD PMID:18363858 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 EXP IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP3 protein] CTD PMID:19463876 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity		 EXP IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP8 protein] CTD PMID:19463876 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cat catalase multiple interactions
decreases expression
increases expression		 EXP Plant Extracts inhibits the reaction [Reserpine results in decreased expression of CAT protein]; Quercetin inhibits the reaction [Reserpine results in decreased expression of CAT protein]
Reserpine results in increased expression of CAT protein		 CTD PMID:14685008 PMID:16444668 PMID:19109989 PMID:19761039 PMID:20628966 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Reserpine results in decreased expression of CCND1 mRNA; Reserpine results in decreased expression of CCND1 protein CTD PMID:19607803 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of CDKN1B protein CTD PMID:11318962 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions EXP [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate affects the localization of CDKN2A protein]; [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine] inhibits the reaction [Desoxycorticosterone Acetate results in increased expression of CDKN2A mRNA] CTD PMID:18504326 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Chga chromogranin A multiple interactions
increases expression
increases activity		 ISO
EXP		 CHGA protein alternative form inhibits the reaction [Reserpine results in increased activity of CHGA promoter]; Chlorisondamine inhibits the reaction [Reserpine results in increased activity of CHGA promoter]
Reserpine results in increased expression of CHGA mRNA		 CTD PMID:1907749 PMID:8189248 PMID:12799369 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398 		JBrowse link
G Chgb chromogranin B increases expression EXP Reserpine results in increased expression of CHGB mRNA; Reserpine results in increased expression of CHGB protein CTD PMID:1907749 PMID:8189248 PMID:8361347 NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166 		JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 increases expression
decreases expression		 EXP Reserpine results in increased expression of CHRM1 mRNA
Reserpine results in decreased expression of CHRM1 protein		 CTD PMID:1506860 NCBI chr 1:205,567,226...205,583,001
Ensembl chr 1:205,567,220...205,582,356 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Reserpine results in decreased expression of CNR1 mRNA CTD PMID:11358453 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Cpe carboxypeptidase E increases expression EXP Reserpine results in increased expression of CPE mRNA CTD PMID:8189248 NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233 		JBrowse link
G Crem cAMP responsive element modulator multiple interactions
increases expression		 EXP Reserpine promotes the reaction [CREM protein binds to TH promoter]
Reserpine results in increased expression of CREM mRNA alternative form; Reserpine results in increased expression of CREM protein; Reserpine results in increased expression of CREM protein alternative form		 CTD PMID:8810303 PMID:11438978 NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989 		JBrowse link
G Crh corticotropin releasing hormone increases expression EXP Reserpine results in increased expression of CRH mRNA; Reserpine results in increased expression of CRH protein CTD PMID:1850078 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions ISO Reserpine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of CYP1A1 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A1 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA] CTD PMID:15627480 PMID:18493746 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; [Reserpine results in decreased abundance of Catecholamines] promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of and results in increased activity of CYP1A2 protein]; Reserpine promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA] CTD PMID:16510159 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO [Reserpine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA CTD PMID:17041008 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases expression
multiple interactions		 ISO Reserpine results in increased expression of CYP3A4 mRNA; Reserpine results in increased expression of CYP3A4 protein
[Reserpine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA; Reserpine inhibits the reaction [Calcitriol results in increased expression of CYP3A4 protein]		 CTD PMID:8632764 PMID:16837568 PMID:17041008 PMID:29782822 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 increases expression ISO Reserpine results in increased expression of CYP3A5 protein CTD PMID:8632764 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Cyss cystatin S multiple interactions EXP Reserpine inhibits the reaction [Isoproterenol results in increased expression of CYSS mRNA] CTD PMID:9447264 NCBI chr 3:137,432,049...137,436,654
Ensembl chr 3:137,432,049...137,436,610 		JBrowse link
G Dbh dopamine beta-hydroxylase decreases activity
increases expression
increases stability
increases activity		 EXP Reserpine results in decreased activity of DBH protein
Reserpine results in increased expression of DBH mRNA
Reserpine results in increased stability of DBH protein
Reserpine results in increased activity of DBH protein		 CTD PMID:1359376 PMID:2325165 PMID:7984052 PMID:8189248 NCBI chr 3:10,488,260...10,505,245
Ensembl chr 3:10,488,260...10,505,248 		JBrowse link
G Ddc dopa decarboxylase increases expression EXP Reserpine results in increased expression of DDC mRNA CTD PMID:1359376 NCBI chr14:86,378,685...86,469,189
Ensembl chr14:86,378,685...86,469,208 		JBrowse link
G Drd1 dopamine receptor D1 increases expression EXP Reserpine results in increased expression of DRD1 mRNA CTD PMID:8419537 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
increases expression		 ISO
EXP		 DRD2 protein affects the susceptibility to [8-(3-chlorostyryl)caffeine co-treated with Reserpine]
Reserpine results in increased expression of DRD2 mRNA; Reserpine results in increased expression of DRD2 mRNA alternative form		 CTD PMID:1331675 PMID:8419537 PMID:11172060 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Egr1 early growth response 1 multiple interactions
increases expression		 EXP [Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA; eticlopride inhibits the reaction [[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA]; Quinpirole inhibits the reaction [Reserpine results in increased expression of EGR1 mRNA]; Reserpine promotes the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [[Reserpine co-treated with Levodopa] results in increased expression of EGR1 mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of EGR1 mRNA]]
Reserpine results in increased expression of EGR1 mRNA; Reserpine results in increased expression of EGR1 protein		 CTD PMID:1347779 PMID:8063705 PMID:9729266 PMID:9890435 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases response to substance EXP ERBB2 protein results in increased susceptibility to Reserpine CTD PMID:8093862 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Fabp7 fatty acid binding protein 7 affects expression EXP Reserpine affects the expression of FABP7 mRNA CTD PMID:18363858 NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression
increases phosphorylation		 EXP 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine promotes the reaction [Reserpine results in increased expression of FOS protein]; 3,7-dimethyl-1-propargylxanthine inhibits the reaction [Reserpine results in increased expression of FOS protein]; 8-(3-chlorostyryl)caffeine promotes the reaction [Quinpirole inhibits the reaction [Reserpine results in increased expression of FOS protein]]; Quinpirole inhibits the reaction [Reserpine results in increased expression of FOS protein]; Quinpirole promotes the reaction [Reserpine results in increased expression of FOS protein]; Reserpine inhibits the reaction [[2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Quinpirole] results in increased expression of FOS protein]; Reserpine inhibits the reaction [Cocaine results in increased expression of FOS protein]; Reserpine promotes the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased expression of FOS protein]; Reserpine promotes the reaction [Amphetamine results in increased expression of FOS protein]; Reserpine promotes the reaction [Quinpirole results in increased expression of FOS protein]; Theophylline inhibits the reaction [Reserpine results in increased expression of FOS protein]
Reserpine results in increased expression of FOS mRNA; Reserpine results in increased expression of FOS protein
Reserpine results in increased phosphorylation of FOS protein		 CTD PMID:1359376 PMID:1686849 PMID:2118661 PMID:7845612 PMID:7914358 More... NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Gad1 glutamate decarboxylase 1 increases expression
multiple interactions		 EXP Reserpine results in increased expression of GAD1 mRNA
Clenbuterol inhibits the reaction [Reserpine results in increased expression of GAD1 mRNA]		 CTD PMID:8774452 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gal galanin and GMAP prepropeptide decreases expression
increases expression
multiple interactions		 EXP Reserpine results in decreased expression of GAL mRNA
Reserpine results in increased expression of GAL mRNA
Desipramine inhibits the reaction [Reserpine results in increased expression of GAL mRNA]		 CTD PMID:1279347 PMID:1698642 PMID:1705056 PMID:1717808 PMID:9512271 More... NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959 		JBrowse link
G Gast gastrin multiple interactions EXP Reserpine inhibits the reaction [Levodopa results in decreased cleavage of GAST protein] CTD PMID:10332097 NCBI chr10:85,264,832...85,269,393
Ensembl chr10:85,264,832...85,267,496 		JBrowse link
G Gch1 GTP cyclohydrolase 1 increases expression EXP Reserpine results in increased expression of GCH1 mRNA; Reserpine results in increased expression of GCH1 mRNA alternative form CTD PMID:8103077 NCBI chr15:20,404,267...20,437,727
Ensembl chr15:20,402,527...20,437,698 		JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Reserpine results in increased expression of GCNT3 mRNA CTD PMID:26198647 NCBI chr 8:70,689,173...70,696,476
Ensembl chr 8:70,686,844...70,699,562 		JBrowse link
G Gnai1 G protein subunit alpha i1 increases expression EXP Reserpine results in increased expression of GNAI1 protein CTD PMID:11264240 NCBI chr 4:16,814,000...16,898,119
Ensembl chr 4:16,814,001...16,896,417 		JBrowse link
G Gnai2 G protein subunit alpha i2 increases expression EXP Reserpine results in increased expression of GNAI2 mRNA; Reserpine results in increased expression of GNAI2 protein CTD PMID:8419537 PMID:11264240 NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979 		JBrowse link
G Gnai3 G protein subunit alpha i3 increases expression EXP Reserpine results in increased expression of GNAI3 protein CTD PMID:11264240 NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742 		JBrowse link
G Gnao1 G protein subunit alpha o1 increases expression EXP Reserpine results in increased expression of GNAO1 mRNA; Reserpine results in increased expression of GNAO1 protein CTD PMID:8419537 PMID:11264240 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnas GNAS complex locus increases expression
decreases expression		 EXP Reserpine results in increased expression of GNAS mRNA; Reserpine results in increased expression of GNAS protein
Reserpine results in decreased expression of GNAS protein alternative form		 CTD PMID:1336118 PMID:8419537 PMID:11264240 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Grm5 glutamate metabotropic receptor 5 decreases expression
increases expression		 EXP Reserpine results in decreased expression of GRM5 mRNA
Reserpine results in increased expression of GRM5 protein		 CTD PMID:16890937 NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274 		JBrowse link
G Hgf hepatocyte growth factor increases expression EXP Reserpine results in increased expression of HGF protein CTD PMID:16081063 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hspg2 heparan sulfate proteoglycan 2 multiple interactions ISO HSPG2 gene results in increased susceptibility to [Haloperidol co-treated with Reserpine] CTD PMID:20072119 NCBI chr 5:149,677,437...149,778,594
Ensembl chr 5:149,677,476...149,778,594 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A decreases expression ISO Reserpine results in decreased expression of HTR1A protein CTD PMID:26114099 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Iapp islet amyloid polypeptide multiple interactions EXP IAPP protein inhibits the reaction [Reserpine results in decreased expression of BCL2 protein]; IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP3 protein]; IAPP protein inhibits the reaction [Reserpine results in increased activity of CASP8 protein]; IAPP protein inhibits the reaction [Reserpine results in increased expression of BAX protein]; IAPP protein inhibits the reaction [Reserpine results in increased expression of TNFSF10 protein] CTD PMID:19463876 NCBI chr 4:175,237,107...175,244,373
Ensembl chr 4:175,237,115...175,242,920 		JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions		 ISO Reserpine results in decreased expression of IL10 mRNA; Reserpine results in decreased expression of IL10 protein
SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 mRNA]; SCH 23390 inhibits the reaction [Reserpine results in decreased expression of IL10 protein]		 CTD PMID:16985181 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il18 interleukin 18 increases expression EXP Reserpine results in increased expression of IL18 mRNA CTD PMID:8999896 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression EXP Reserpine results in increased expression of JUN mRNA CTD PMID:1359376 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Junb JunB proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]; SCH 23390 inhibits the reaction [Reserpine promotes the reaction [Dextroamphetamine results in increased expression of JUNB mRNA]] CTD PMID:1347779 NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035 		JBrowse link
G Kcna3 potassium voltage-gated channel subfamily A member 3 decreases activity
multiple interactions		 ISO Reserpine results in decreased activity of KCNA3 protein
[Reserpine results in decreased activity of KCNA3 protein] which results in decreased import of Thallium		 CTD PMID:21362439 NCBI chr 2:194,632,106...194,634,059
Ensembl chr 2:194,632,196...194,650,138 		JBrowse link
G Kcna5 potassium voltage-gated channel subfamily A member 5 increases expression EXP Reserpine results in increased expression of KCNA5 mRNA CTD PMID:12606256 NCBI chr 4:159,354,689...159,358,173
Ensembl chr 4:159,350,097...159,357,697 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 decreases expression EXP Reserpine results in decreased expression of KCND2 mRNA CTD PMID:12606256 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728 		JBrowse link
G Kcnd3 potassium voltage-gated channel subfamily D member 3 decreases expression EXP Reserpine results in decreased expression of KCND3 mRNA CTD PMID:12606256 NCBI chr 2:192,937,950...193,155,345
Ensembl chr 2:192,937,950...193,155,345 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions		 ISO Reserpine results in decreased activity of KCNH2 protein
[Reserpine results in decreased activity of KCNH2 protein] which results in decreased import of Thallium		 CTD PMID:21362439 PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Lep leptin increases expression ISO Reserpine results in increased expression of LEP mRNA CTD PMID:10050748 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases response to substance
decreases expression		 ISO MYC protein results in increased susceptibility to Reserpine
Reserpine results in decreased expression of MYC protein		 CTD PMID:8093862 PMID:19607803 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 increases expression EXP Reserpine results in increased expression of NCF1 mRNA; Reserpine results in increased expression of NCF1 protein CTD PMID:20964730 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases activity ISO Reserpine results in decreased activity of NFE2L2 protein CTD PMID:30203046 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngf nerve growth factor increases expression EXP Reserpine results in increased expression of NGF mRNA; Reserpine results in increased expression of NGF protein CTD PMID:1996081 PMID:8593794 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Nos1 nitric oxide synthase 1 increases expression EXP Reserpine results in increased expression of NOS1 mRNA; Reserpine results in increased expression of NOS1 protein CTD PMID:7533141 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Npy neuropeptide Y multiple interactions
increases expression
decreases expression		 EXP Chlorisondamine inhibits the reaction [Reserpine results in increased expression of NPY mRNA]; Chlorisondamine promotes the reaction [Reserpine results in increased expression of NPY mRNA]; Dexamethasone inhibits the reaction [Reserpine results in increased expression of NPY mRNA]
Reserpine results in increased expression of NPY mRNA; Reserpine results in increased expression of NPY protein
Reserpine results in decreased expression of NPY mRNA; Reserpine results in decreased expression of NPY protein		 CTD PMID:1671012 PMID:1676830 PMID:1687976 PMID:1698642 PMID:1713314 More... NCBI chr 4:78,881,294...78,888,495
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO [Reserpine results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:17041008 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions
decreases activity		 ISO [Reserpine results in increased activity of NR1I3 protein alternative form] which results in increased expression of CYP2B6 mRNA
Reserpine results in decreased activity of NR1I3 protein		 CTD PMID:17041008 PMID:30203046 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 increases expression EXP Reserpine results in increased expression of NR3C1 mRNA CTD PMID:7984052 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions
decreases expression		 ISO arsenic trioxide promotes the reaction [Reserpine results in decreased expression of NTRK2 protein] CTD PMID:26114099 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Nts neurotensin increases expression EXP Reserpine results in increased expression of NTS mRNA CTD PMID:1850078 NCBI chr 7:37,564,944...37,574,350
Ensembl chr 7:37,564,533...37,574,423 		JBrowse link
G Odc1 ornithine decarboxylase 1 decreases expression
multiple interactions		 EXP
ISO		 Reserpine results in decreased expression of ODC1 protein
Reserpine inhibits the reaction [CB 3717 results in increased activity of ODC1 protein]; Reserpine inhibits the reaction [CB 3717 results in increased expression of ODC1 mRNA]; Reserpine inhibits the reaction [Testosterone results in increased activity of ODC1 protein]; Reserpine inhibits the reaction [Testosterone results in increased expression of ODC1 mRNA]		 CTD PMID:6519379 PMID:9194572 PMID:10354516 PMID:17371283 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Pam peptidylglycine alpha-amidating monooxygenase increases expression EXP Reserpine results in increased expression of PAM mRNA CTD PMID:8189248 NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of PCNA protein CTD PMID:11318962 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pcsk2 proprotein convertase subtilisin/kexin type 2 increases expression EXP Reserpine results in increased expression of PCSK2 mRNA CTD PMID:8189248 NCBI chr 3:130,880,422...131,183,127
Ensembl chr 3:130,880,422...131,183,127 		JBrowse link
G Penk proenkephalin multiple interactions
increases expression
decreases expression		 EXP Apomorphine inhibits the reaction [Reserpine results in increased expression of PENK mRNA]
Reserpine results in increased expression of PENK mRNA; Reserpine results in increased expression of PENK protein
Reserpine results in decreased expression of PENK mRNA		 CTD PMID:1331675 PMID:1850078 PMID:3188958 PMID:3838946 PMID:4078631 More... NCBI chr 5:17,183,799...17,189,160
Ensembl chr 5:17,183,806...17,189,129 		JBrowse link
G Pnmt phenylethanolamine-N-methyltransferase multiple interactions
increases expression
decreases expression		 EXP Chlorisondamine inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; Dexamethasone inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; POMC protein alternative form inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]; Reserpine results in increased expression of and results in increased activity of PNMT protein
Reserpine results in increased expression of PNMT mRNA		 CTD PMID:1359376 PMID:1687976 PMID:1714554 PMID:2903502 PMID:8063705 More... NCBI chr10:83,383,019...83,386,557
Ensembl chr10:83,384,923...83,386,556 		JBrowse link
G Pomc proopiomelanocortin increases expression
multiple interactions		 EXP Reserpine results in increased expression of POMC mRNA; Reserpine results in increased expression of POMC protein alternative form
POMC protein alternative form inhibits the reaction [Reserpine results in decreased expression of PNMT mRNA]		 CTD PMID:8479280 PMID:20504635 NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha decreases expression ISO Reserpine results in decreased expression of PRKACA protein CTD PMID:26114099 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prl prolactin increases expression EXP Reserpine results in increased expression of PRL protein CTD PMID:11071396 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prss1 serine protease 1 decreases expression
increases expression		 EXP Reserpine results in decreased expression of PRSS1 protein
Reserpine results in increased expression of PRSS1 protein		 CTD PMID:8625754 NCBI chr 4:70,364,589...70,367,792
Ensembl chr 4:70,364,586...70,367,792 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression EXP Reserpine results in increased expression of PTGS2 protein CTD PMID:16081063 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Pts 6-pyruvoyl-tetrahydropterin synthase increases expression EXP Reserpine results in increased expression of PTS mRNA CTD PMID:7545485 NCBI chr 8:50,870,838...50,877,869
Ensembl chr 8:50,870,841...50,877,869 		JBrowse link
G Rasd2 RASD family, member 2 decreases expression EXP Reserpine results in decreased expression of RASD2 mRNA CTD PMID:16352400 NCBI chr19:13,594,291...13,605,016
Ensembl chr19:13,594,291...13,605,016 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 decreases expression EXP Reserpine results in decreased expression of RGS10 mRNA CTD PMID:14505795 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 decreases expression EXP Reserpine results in decreased expression of RGS2 mRNA CTD PMID:14505795 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 decreases expression EXP Reserpine results in decreased expression of RGS4 mRNA CTD PMID:14505795 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs5 regulator of G-protein signaling 5 decreases expression EXP Reserpine results in decreased expression of RGS5 mRNA CTD PMID:14505795 NCBI chr13:81,848,254...81,885,053
Ensembl chr13:81,836,304...81,885,518 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 decreases expression EXP Reserpine results in decreased expression of RGS8 mRNA CTD PMID:14505795 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Rgs9 regulator of G-protein signaling 9 affects response to substance
decreases expression		 ISO
EXP		 RGS9 affects the susceptibility to Reserpine
Reserpine results in decreased expression of RGS9 mRNA		 CTD PMID:14505795 PMID:15728856 NCBI chr10:94,195,265...94,270,892
Ensembl chr10:94,197,054...94,270,892 		JBrowse link
G Scg2 secretogranin II increases expression EXP Reserpine results in increased expression of SCG2 mRNA CTD PMID:1907749 PMID:8189248 PMID:8361347 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097 		JBrowse link
G Serpine1 serpin family E member 1 multiple interactions EXP [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 mRNA; [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 protein CTD PMID:11318962 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Siah1 siah E3 ubiquitin protein ligase 1 increases expression ISO Reserpine results in increased expression of SIAH1 mRNA CTD PMID:19607803 NCBI chr19:20,378,908...20,402,512
Ensembl chr19:20,378,439...20,403,808 		JBrowse link
G Slc18a1 solute carrier family 18 member A1 decreases activity
multiple interactions		 ISO Reserpine results in decreased activity of SLC18A1 protein
Reserpine inhibits the reaction [SLC18A1 protein results in increased uptake of Serotonin]		 CTD PMID:8245983 PMID:21712771 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects binding
multiple interactions
decreases activity
increases expression
affects response to substance
decreases response to substance		 ISO
EXP		 Reserpine binds to SLC18A2 protein
Reserpine inhibits the reaction [SLC18A2 protein results in increased uptake of Dopamine]
Reserpine results in decreased activity of SLC18A2 protein
SLC18A2 protein binds to Reserpine
Reserpine results in increased expression of SLC18A2 mRNA
SLC18A2 affects the susceptibility to Reserpine
Reserpine inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin]; Serotonin inhibits the reaction [SLC18A2 protein binds to Reserpine]
SLC18A2 gene SNP results in decreased susceptibility to Reserpine		 CTD PMID:1438304 PMID:7912402 PMID:8189248 PMID:9038139 PMID:15475732 More... NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 decreases expression EXP Reserpine results in decreased expression of SLC6A2 mRNA CTD PMID:7478180 PMID:7616203 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 decreases activity
affects response to substance		 ISO Reserpine results in decreased activity of SLC6A3 protein
SLC6A3 gene mutant form affects the susceptibility to Reserpine		 CTD PMID:17664021 PMID:19615345 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 decreases expression EXP Reserpine results in decreased expression of SLC6A4 mRNA CTD PMID:10027743 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Snca synuclein alpha affects response to substance ISO SNCA protein mutant form affects the susceptibility to Reserpine CTD PMID:18622040 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sqstm1 sequestosome 1 increases expression ISO Reserpine results in increased expression of SQSTM1 mRNA CTD PMID:26198647 NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Syt7 synaptotagmin 7 multiple interactions EXP [Reserpine co-treated with Apomorphine] results in increased expression of SYT7 mRNA CTD PMID:17719177 NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026 		JBrowse link
G Tac1 tachykinin, precursor 1 multiple interactions
increases expression		 EXP [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine co-treated with Quinpirole] results in increased expression of TAC1 mRNA; [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine co-treated with Reserpine] results in increased expression of TAC1 mRNA; Apomorphine promotes the reaction [Reserpine results in increased expression of TAC1 mRNA] CTD PMID:9751140 PMID:17719177 NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178 		JBrowse link
G Tff1 trefoil factor 1 increases expression ISO Reserpine results in increased expression of TFF1 mRNA CTD PMID:35307500 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Th tyrosine hydroxylase increases expression
increases activity
decreases expression
affects activity
increases stability
multiple interactions		 ISO
EXP		 Reserpine results in increased expression of TH mRNA
Reserpine results in increased activity of TH protein
Reserpine results in increased expression of TH mRNA; Reserpine results in increased expression of TH protein
Reserpine results in decreased expression of TH mRNA
Reserpine affects the activity of TH protein
Reserpine results in increased stability of TH mRNA
Bicuculline promotes the reaction [Reserpine affects the activity of TH protein]; Bicuculline promotes the reaction [Reserpine results in increased expression of TH mRNA]; Chlorisondamine inhibits the reaction [Reserpine results in increased expression of TH mRNA]; Chlorisondamine promotes the reaction [Reserpine results in increased expression of TH mRNA]; Desipramine inhibits the reaction [Reserpine results in increased expression of TH mRNA]; Reserpine promotes the reaction [CREM protein binds to TH promoter]; Reserpine results in increased expression of and results in increased activity of TH protein		 CTD PMID:1350653 PMID:1359376 PMID:1676830 PMID:1687822 PMID:1687976 More... NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP Reserpine results in increased expression of TNF protein
cerebrolysin inhibits the reaction [Reserpine results in increased expression of TNF protein]; Fluoxetine inhibits the reaction [Reserpine results in increased expression of TNF protein]		 CTD PMID:33279466 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions
increases expression		 EXP IAPP protein inhibits the reaction [Reserpine results in increased expression of TNFSF10 protein] CTD PMID:19463876 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tph1 tryptophan hydroxylase 1 increases activity
decreases activity		 EXP Reserpine results in increased activity of TPH1 protein
Reserpine results in decreased activity of TPH1 protein		 CTD PMID:8369965 NCBI chr 1:97,157,375...97,178,415
Ensembl chr 1:97,157,409...97,178,344 		JBrowse link
G Vgf VGF nerve growth factor inducible increases expression EXP Reserpine results in increased expression of VGF mRNA CTD PMID:8189248 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341 		JBrowse link
G Vip vasoactive intestinal peptide increases expression EXP Reserpine results in increased expression of VIP mRNA CTD PMID:1850078 NCBI chr 1:42,064,878...42,073,219
Ensembl chr 1:42,065,120...42,073,216 		JBrowse link
risperidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects abundance
multiple interactions
increases export
increases transport
decreases activity
affects response to substance
increases response to substance		 ISO
EXP		 ABCB1 gene polymorphism affects the abundance of Risperidone; ABCB1 protein affects the abundance of Risperidone
Cyclosporine inhibits the reaction [ABCB1A protein results in increased export of Risperidone]
ABCB1A protein results in increased transport of Risperidone
Risperidone results in decreased activity of ABCB1 protein
ABCB1A protein affects the susceptibility to Risperidone
ABCB1 protein results in increased transport of Risperidone
Risperidone inhibits the reaction [ABCB1 protein results in decreased export of Doxorubicin]
ABCB1 protein results in increased susceptibility to Risperidone
ABCB1 gene polymorphism affects the susceptibility to Risperidone; ABCB1 protein affects the susceptibility to Risperidone		 CTD PMID:15502009 PMID:16118767 PMID:16810505 PMID:16936711 PMID:17054409 More... NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B affects response to substance ISO ABCB1B protein affects the susceptibility to Risperidone CTD PMID:15502009 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Risperidone inhibits the reaction [ABCG2 protein results in increased transport of Mitoxantrone]; Risperidone inhibits the reaction [ABCG2 protein results in increased uptake of estrone sulfate] CTD PMID:18834354 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing multiple interactions
increases expression		 ISO Berberine inhibits the reaction [Risperidone results in increased expression of ADIPOQ mRNA] CTD PMID:20564506 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
multiple interactions		 EXP
ISO		 Risperidone results in decreased expression of BDNF mRNA
BDNF gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]
Risperidone inhibits the reaction [Rotenone results in decreased expression of BDNF mRNA]		 CTD PMID:12393228 PMID:17442543 PMID:19997080 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Calm2 calmodulin 2 increases expression EXP Risperidone results in increased expression of CALM2 mRNA CTD PMID:19289156 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287
Ensembl chr15:7,091,567...7,104,287 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha decreases expression EXP Risperidone results in decreased expression of CAMK2A protein CTD PMID:19289156 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression EXP Risperidone results in decreased expression of CAMK4 protein CTD PMID:19289156 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 decreases expression EXP Risperidone results in decreased expression of CAMKK1 protein CTD PMID:19289156 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 decreases expression EXP Risperidone results in decreased expression of CAMKK2 protein CTD PMID:19289156 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity		 ISO Palmitic Acid promotes the reaction [Risperidone results in increased activity of CASP3 protein] CTD PMID:22700542 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 multiple interactions
increases activity		 ISO Palmitic Acid promotes the reaction [Risperidone results in increased activity of CASP7 protein] CTD PMID:22700542 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha multiple interactions
increases expression		 ISO Berberine inhibits the reaction [Risperidone results in increased expression of CEBPA mRNA]; Berberine inhibits the reaction [Risperidone results in increased expression of CEBPA protein]
Risperidone results in increased expression of CEBPA mRNA; Risperidone results in increased expression of CEBPA protein		 CTD PMID:20564506 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412 		JBrowse link
G Chrm4 cholinergic receptor, muscarinic 4 affects response to substance ISO CHRM4 affects the susceptibility to Risperidone CTD PMID:21269601 NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159 		JBrowse link
G Comt catechol-O-methyltransferase increases expression EXP Risperidone results in increased expression of COMT mRNA CTD PMID:15964593 NCBI chr11:82,568,052...82,587,642
Ensembl chr11:82,568,025...82,587,642 		JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Risperidone results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Ctnnb1 catenin beta 1 multiple interactions
increases expression		 EXP DRD2 protein affects the reaction [Risperidone results in increased expression of CTNNB1 protein] CTD PMID:16144542 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 affects metabolic processing
increases metabolic processing
increases response to substance
affects response to substance
decreases hydroxylation
decreases metabolic processing
affects abundance
multiple interactions		 ISO CYP2D6 gene polymorphism affects the metabolism of Risperidone; CYP2D6 protein affects the metabolism of Risperidone
CYP2D6 protein results in increased metabolism of Risperidone
CYP2D6 protein results in increased susceptibility to Risperidone
CYP2D6 gene polymorphism affects the susceptibility to Risperidone; CYP2D6 protein polymorphism affects the susceptibility to Risperidone
CYP2D6 gene polymorphism results in decreased hydroxylation of Risperidone
CYP2D6 gene polymorphism results in decreased metabolism of Risperidone
CYP2D6 gene polymorphism affects the abundance of Risperidone; CYP2D6 protein affects the abundance of Risperidone
CYP2D6 gene polymorphism affects the metabolism of and affects the abundance of Risperidone; CYP2D6 protein affects the metabolism of and affects the abundance of Risperidone		 CTD PMID:10639689 PMID:15089809 PMID:15260906 PMID:15565299 PMID:15669884 More... NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
affects response to substance		 ISO N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Risperidone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Risperidone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]
CYP3A4 gene polymorphism affects the susceptibility to Risperidone; CYP3A4 protein affects the susceptibility to Risperidone		 CTD PMID:19395426 PMID:21402137 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 affects abundance
increases metabolic processing		 ISO CYP3A5 gene polymorphism affects the abundance of Risperidone; CYP3A5 protein affects the abundance of Risperidone
CYP3A5 protein results in increased metabolism of Risperidone		 CTD PMID:18708991 PMID:20332423 NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects binding
increases response to substance
affects response to substance		 ISO
EXP		 Risperidone binds to and results in decreased activity of DRD2 protein
Risperidone binds to DRD2 protein
[Risperidone binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein; DRD2 protein affects the reaction [Risperidone results in increased expression of CTNNB1 protein]; DRD2 protein affects the reaction [Risperidone results in increased expression of DVL3 protein]; DRD2 protein affects the reaction [Risperidone results in increased expression of GSK3A protein]; DRD2 protein affects the reaction [Risperidone results in increased expression of GSK3B protein]; Risperidone binds to and results in decreased activity of DRD2 protein; Risperidone inhibits the reaction [Apomorphine binds to and results in increased activity of DRD2 protein]; Risperidone promotes the reaction [Dopamine binds to DRD2 protein]
DRD2 gene polymorphism results in increased susceptibility to Risperidone; DRD2 gene SNP results in increased susceptibility to Risperidone; DRD2 protein results in increased susceptibility to Risperidone
DRD2 gene polymorphism affects the susceptibility to Risperidone		 CTD PMID:1380082 PMID:7520908 PMID:8804920 PMID:10831489 PMID:12191584 More... NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 increases response to substance ISO DRD3 gene SNP results in increased susceptibility to Risperidone; DRD3 protein results in increased susceptibility to Risperidone CTD PMID:19506579 PMID:19997080 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 multiple interactions
increases expression		 EXP DRD2 protein affects the reaction [Risperidone results in increased expression of DVL3 protein] CTD PMID:16144542 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Egr1 early growth response 1 decreases expression EXP Risperidone results in decreased expression of EGR1 protein CTD PMID:17028028 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 decreases expression
multiple interactions		 EXP
ISO		 Risperidone results in decreased expression of EGR2 protein
Risperidone inhibits the reaction [Toluene promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of EGR2 protein]]		 CTD PMID:17028028 PMID:32980479 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Erbb2 erb-b2 receptor tyrosine kinase 2 increases phosphorylation EXP Risperidone results in increased phosphorylation of ERBB2 protein CTD PMID:26961615 NCBI chr10:83,411,197...83,435,078
Ensembl chr10:83,411,313...83,435,078 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 multiple interactions EXP Risperidone results in increased expression of and results in increased phosphorylation of ERBB4 protein CTD PMID:26961615 NCBI chr 9:69,523,733...70,596,743
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Fads2 fatty acid desaturase 2 increases expression
multiple interactions		 EXP Risperidone results in increased expression of FADS2 mRNA
[Risperidone results in increased expression of FADS2 mRNA] which results in increased abundance of Fatty Acids, Unsaturated		 CTD PMID:21458237 NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions
increases expression		 ISO Berberine inhibits the reaction [Risperidone results in increased expression of FAS mRNA] CTD PMID:20564506 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 EXP
ISO		 Risperidone promotes the reaction [Rotenone results in increased expression of FOS mRNA]
Dronabinol inhibits the reaction [Risperidone results in increased expression of FOS protein]; Risperidone inhibits the reaction [Toluene promotes the reaction [4-iodo-2,5-dimethoxyphenylisopropylamine results in increased expression of FOS protein]]
Risperidone results in increased expression of FOS mRNA		 CTD PMID:11516571 PMID:17442543 PMID:28272498 PMID:32980479 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fshb follicle stimulating hormone subunit beta affects expression ISO Risperidone affects the expression of FSHB protein CTD PMID:18838228 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Ggt1 gamma-glutamyltransferase 1 multiple interactions EXP Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GGT1 protein]; coenzyme Q10 inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GGT1 protein]; Risperidone results in increased expression of and results in increased secretion of GGT1 protein CTD PMID:27387968 NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 multiple interactions EXP Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GOT1 protein]; coenzyme Q10 inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GOT1 protein]; Risperidone results in increased expression of and results in increased secretion of GOT1 protein CTD PMID:27387968 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GPT protein]; coenzyme Q10 inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GPT protein]; Risperidone results in increased expression of and results in increased secretion of GPT protein CTD PMID:27387968 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha increases expression
multiple interactions		 EXP Risperidone results in increased expression of GSK3A protein
DRD2 protein affects the reaction [Risperidone results in increased expression of GSK3A protein]		 CTD PMID:16144542 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases expression		 EXP DRD2 protein affects the reaction [Risperidone results in increased expression of GSK3B protein] CTD PMID:16144542 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO Risperidone results in increased expression of HMGCR mRNA CTD PMID:17052361 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Homer1 homer scaffold protein 1 increases expression EXP Risperidone results in increased expression of HOMER1 mRNA CTD PMID:20147574 NCBI chr 2:24,542,777...24,645,715
Ensembl chr 2:24,543,093...24,644,785 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A increases response to substance
multiple interactions		 EXP HTR1A protein results in increased susceptibility to Risperidone
N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide inhibits the reaction [HTR1A protein results in increased susceptibility to Risperidone]		 CTD PMID:17530476 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A increases response to substance
affects binding
multiple interactions
affects response to substance		 ISO
EXP		 HTR2A gene SNP results in increased susceptibility to Risperidone; HTR2A protein results in increased susceptibility to Risperidone
Risperidone binds to HTR2A protein
Risperidone binds to and results in decreased activity of HTR2A protein; Risperidone inhibits the reaction [Ketanserin binds to HTR2A protein]
HTR2A gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]; Risperidone binds to and results in decreased activity of HTR2A protein
HTR2A protein affects the susceptibility to Risperidone		 CTD PMID:7520908 PMID:11927170 PMID:12191584 PMID:16314884 PMID:16948927 More... NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2c 5-hydroxytryptamine receptor 2C affects response to substance
multiple interactions
increases response to substance		 ISO HTR2C gene polymorphism affects the susceptibility to Risperidone; HTR2C protein affects the susceptibility to Risperidone
HTR2C gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]
HTR2C protein results in increased susceptibility to Risperidone		 CTD PMID:19142101 PMID:19997080 NCBI chr  X:110,640,777...110,870,288
Ensembl chr  X:110,641,153...110,870,287 		JBrowse link
G Htr6 5-hydroxytryptamine receptor 6 multiple interactions ISO HTR6 gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein] CTD PMID:19997080 NCBI chr 5:151,295,269...151,312,853
Ensembl chr 5:151,296,662...151,311,912 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO 2-((2-(dimethylamino)ethyl)thio)-3-phenylquinoline inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]; [Risperidone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [Colforsin results in increased abundance of Cyclic AMP]; Clozapine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]; Cyproheptadine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]; mesulergine inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]; Mianserin inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein]; Risperidone binds to and results in decreased activity of HTR7 protein; SB 269970 inhibits the reaction [Risperidone binds to and results in decreased activity of HTR7 protein] CTD PMID:18996971 PMID:19509219 PMID:20827463 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Inha inhibin subunit alpha multiple interactions ISO Risperidone results in increased expression of [INHA protein binds to INHBB protein] CTD PMID:18838228 NCBI chr 9:76,994,465...76,997,366
Ensembl chr 9:76,993,589...76,997,248 		JBrowse link
G Inhbb inhibin subunit beta B multiple interactions ISO Risperidone results in increased expression of [INHA protein binds to INHBB protein] CTD PMID:18838228 NCBI chr13:30,530,860...30,536,566
Ensembl chr13:30,530,860...30,537,832 		JBrowse link
G Ins2 insulin 2 increases expression ISO Risperidone results in increased expression of INS protein CTD PMID:11927762 PMID:16601995 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Risperidone inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions
increases expression		 ISO Berberine inhibits the reaction [Risperidone results in increased expression of LDLR mRNA] CTD PMID:20564506 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580 		JBrowse link
G Maoa monoamine oxidase A affects response to substance
increases response to substance		 ISO MAOA gene polymorphism affects the susceptibility to Risperidone
MAOA protein results in increased susceptibility to Risperidone		 CTD PMID:22544010 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593 		JBrowse link
G Maob monoamine oxidase B increases expression EXP Risperidone results in increased expression of MAOB mRNA CTD PMID:15964593 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003 		JBrowse link
G Map2 microtubule-associated protein 2 increases expression EXP Risperidone results in increased expression of MAP2 mRNA CTD PMID:15079866 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Ngfr nerve growth factor receptor decreases expression EXP Risperidone results in decreased expression of NGFR mRNA CTD PMID:12111809 PMID:16513140 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Risperidone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA]]; Risperidone promotes the reaction [NR1I2 protein results in increased expression of CYP3A4 mRNA] CTD PMID:21402137 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nrg1 neuregulin 1 increases expression EXP Risperidone results in increased expression of NRG1 protein CTD PMID:26961615 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma increases expression
multiple interactions		 ISO Risperidone results in increased expression of PPARG mRNA; Risperidone results in increased expression of PPARG protein
Berberine inhibits the reaction [Risperidone results in increased expression of PPARG mRNA]; Berberine inhibits the reaction [Risperidone results in increased expression of PPARG protein]		 CTD PMID:20564506 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha multiple interactions
decreases expression		 EXP [Risperidone binds to and results in decreased activity of DRD2 protein] which results in increased expression of PPP3CA protein
Risperidone results in decreased expression of PPP3CA mRNA; Risperidone results in decreased expression of PPP3CA protein		 CTD PMID:16033416 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Prl prolactin multiple interactions
increases secretion
increases expression		 ISO
EXP		 [Risperidone co-treated with Clozapine] results in increased expression of PRL protein; Aripiprazole inhibits the reaction [Risperidone results in increased secretion of PRL protein]; BDNF gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]; HTR2A gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]; HTR2C gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]; HTR6 gene polymorphism affects the reaction [Risperidone results in increased expression of PRL protein]
Risperidone inhibits the reaction [Dopamine results in decreased secretion of PRL protein]		 CTD PMID:1380082 PMID:9696519 PMID:9989566 PMID:10084644 PMID:11048906 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 increases expression EXP Risperidone results in increased expression of RGS2 mRNA CTD PMID:11516571 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G S100b S100 calcium binding protein B increases secretion EXP Risperidone results in increased secretion of S100B protein CTD PMID:18421423 NCBI chr20:12,372,866...12,381,619
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Slc17a6 solute carrier family 17 member 6 increases expression ISO Risperidone results in increased expression of SLC17A6 mRNA; Risperidone results in increased expression of SLC17A6 protein CTD PMID:18155072 NCBI chr 1:101,212,489...101,252,543
Ensembl chr 1:101,212,489...101,252,542 		JBrowse link
G Snap25 synaptosome associated protein 25 affects response to substance ISO SNAP25 gene SNP affects the susceptibility to Risperidone CTD PMID:15823421 NCBI chr 3:124,041,898...124,123,761
Ensembl chr 3:124,041,898...124,123,760 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression		 EXP Risperidone inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SOD1 mRNA]; Risperidone inhibits the reaction [Haloperidol results in decreased expression of SOD1 protein]
Risperidone results in increased expression of SOD1 mRNA		 CTD PMID:12111809 PMID:12752374 PMID:16564057 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 ISO Berberine inhibits the reaction [Risperidone results in increased expression of SREBF1 mRNA]; Berberine inhibits the reaction [Risperidone results in increased expression of SREBF1 protein]
Risperidone results in increased expression of SREBF1 mRNA; Risperidone results in increased expression of SREBF1 protein		 CTD PMID:20564506 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions EXP Risperidone inhibits the reaction [Rotenone results in decreased expression of STAT3 mRNA] CTD PMID:17442543 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Th tyrosine hydroxylase increases expression EXP Risperidone results in increased expression of TH protein CTD PMID:17028028 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
ritanserin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdnf brain-derived neurotrophic factor increases expression EXP Ritanserin results in increased expression of BDNF mRNA CTD PMID:12393228 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions
affects binding		 ISO
EXP		 Ritanserin binds to and results in decreased activity of HTR2A protein
Ritanserin binds to HTR2A protein		 CTD PMID:8937629 PMID:17031071 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B multiple interactions ISO Ritanserin binds to and results in decreased activity of HTR2B protein CTD PMID:10978843 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Ritanserin binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP] CTD PMID:14578406 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Ritanserin inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:19583963 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Pdyn prodynorphin increases expression EXP Ritanserin results in increased expression of PDYN mRNA CTD PMID:9526047 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO Ritanserin results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
sertindole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity
multiple interactions		 ISO sertindole results in decreased activity of KCNH2 protein
sertindole inhibits the reaction [KCNH2 protein results in increased transport of Thallium]		 CTD PMID:16278312 PMID:21158687 PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
spiperone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions EXP Spiperone inhibits the reaction [Bromocriptine results in increased expression of ABCB1 protein]; Spiperone inhibits the reaction [N-n-propylnorapomorphine results in increased expression of ABCB1 protein]; Spiperone inhibits the reaction [Quinpirole results in increased expression of ABCB1 protein] CTD PMID:9111066 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, sub-family B member 1B multiple interactions EXP Spiperone inhibits the reaction [Bromocriptine results in increased activity of ABCB1B promoter]; Spiperone inhibits the reaction [N-n-propylnorapomorphine results in increased activity of ABCB1B promoter]; Spiperone inhibits the reaction [Quinpirole results in increased activity of ABCB1B promoter] CTD PMID:9111066 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Adra1a adrenoceptor alpha 1A multiple interactions EXP Spiperone inhibits the reaction [Norepinephrine results in increased activity of ADRA1A protein] CTD PMID:10416824 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Drd1 dopamine receptor D1 multiple interactions EXP Spiperone inhibits the reaction [A 86929 promotes the reaction [DRD1 protein results in increased chemical synthesis of Cyclic AMP]] CTD PMID:8558425 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions
affects binding		 ISO
EXP		 amitraz inhibits the reaction [Spiperone binds to DRD2 protein]; demethylchlordimeform inhibits the reaction [Spiperone binds to DRD2 protein]; NR3C1 protein promotes the reaction [Spiperone binds to DRD2 protein]
Melitten inhibits the reaction [Spiperone binds to DRD2 protein]
8-fluoro-12-(4-methylpiperazin-1-yl)-6H-(1)benzothieno(2,3-b)(1,5)benzodiazepine inhibits the reaction [Spiperone binds to DRD2 protein]; Amphetamine inhibits the reaction [Spiperone binds to DRD2 protein]; Caffeine inhibits the reaction [N-Methyl-3,4-methylenedioxyamphetamine promotes the reaction [Spiperone binds to DRD2 protein]]; Cocaine affects the reaction [Spiperone binds to DRD2 protein]; Haloperidol inhibits the reaction [Spiperone binds to DRD2 protein]; manganese chloride inhibits the reaction [DRD2 protein binds to Spiperone]; N-Methyl-3,4-methylenedioxyamphetamine promotes the reaction [Spiperone binds to DRD2 protein]; perospirone inhibits the reaction [Spiperone binds to DRD2 protein]; Pilocarpine inhibits the reaction [Spiperone binds to DRD2 protein]; Pilocarpine promotes the reaction [Spiperone binds to DRD2 protein]; Remoxipride inhibits the reaction [Spiperone binds to DRD2 protein]; Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]]		 CTD PMID:1975278 PMID:2018630 PMID:2833825 PMID:6149133 PMID:8804920 More... NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd3 dopamine receptor D3 affects binding
multiple interactions		 ISO Spiperone binds to DRD3 protein
N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Spiperone binds to DRD3 protein]		 CTD PMID:21999579 PMID:29458138 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596 		JBrowse link
G Drd4 dopamine receptor D4 affects binding
multiple interactions		 ISO
EXP		 Spiperone binds to DRD4 protein
Spiperone binds to Drd4 protein
N-Methyl-3,4-methylenedioxyamphetamine inhibits the reaction [Spiperone binds to DRD4 protein]		 CTD
RGD		 PMID:21999579 PMID:29458138 PMID:8078498 RGD:7248459 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP
ISO		 Spiperone binds to and results in decreased activity of HTR1A protein CTD PMID:2207497 PMID:15482641 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO Spiperone inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:2891550 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Htr7 5-hydroxytryptamine receptor 7 multiple interactions ISO [Spiperone binds to and results in decreased activity of HTR7 protein] inhibits the reaction [5-carboxamidotryptamine results in increased abundance of Cyclic AMP] CTD PMID:14578406 NCBI chr 1:233,636,442...233,761,063
Ensembl chr 1:233,636,452...233,760,626 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO NR3C1 protein promotes the reaction [Spiperone binds to DRD2 protein] CTD PMID:11226678 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Spiperone inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Th tyrosine hydroxylase multiple interactions EXP Spiperone inhibits the reaction [Cocaine promotes the reaction [[DRD2 protein results in increased phosphorylation of TH protein] which results in increased abundance of Dopamine]] CTD PMID:20729865 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
sulpiride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions
increases transport		 ISO Verapamil inhibits the reaction [ABCB1 protein results in increased transport of Sulpiride] CTD PMID:28597291 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions
increases transport		 ISO Elacridar inhibits the reaction [ABCG2 protein results in increased transport of Sulpiride] CTD PMID:28597291 NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409 		JBrowse link
G Adcy5 adenylate cyclase 5 increases response to substance ISO ADCY5 protein results in increased susceptibility to Sulpiride CTD PMID:12223546 NCBI chr11:65,471,612...65,618,877
Ensembl chr11:65,471,612...65,618,974 		JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
decreases expression		 EXP Sulpiride inhibits the reaction [Benzo(a)pyrene results in increased expression of AHR mRNA]
Sulpiride results in decreased expression of AHR mRNA		 CTD PMID:26466350 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Ahrr aryl-hydrocarbon receptor repressor multiple interactions EXP Sulpiride promotes the reaction [Benzo(a)pyrene results in increased expression of AHRR mRNA] CTD PMID:26466350 NCBI chr 1:28,993,634...29,088,673
Ensembl chr 1:28,993,634...29,088,673 		JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of AIF1 protein] CTD PMID:30922767 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 decreases expression EXP Sulpiride results in decreased expression of AKR1C3 mRNA CTD PMID:21427058 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions EXP Sulpiride inhibits the reaction [Benzo(a)pyrene results in increased expression of ARNT mRNA] CTD PMID:26466350 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of BAX protein] CTD PMID:30922767 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of BCL2 protein] CTD PMID:30922767 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Cacna2d1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 multiple interactions ISO Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] CTD PMID:20340177 NCBI chr 4:18,950,611...19,374,969
Ensembl chr 4:18,951,002...19,374,969 		JBrowse link
G Car2 carbonic anhydrase 2 multiple interactions ISO Sulpiride binds to and results in decreased activity of CA2 protein CTD PMID:17826101 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car3 carbonic anhydrase 3 multiple interactions ISO Sulpiride binds to and results in decreased activity of CA3 protein CTD PMID:17826101 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased cleavage of CASP3 protein] CTD PMID:30922767 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cat catalase multiple interactions ISO Sulpiride promotes the reaction [Lipopolysaccharides inhibits the reaction [Corticosterone results in increased activity of CAT protein]] CTD PMID:14730115 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cckbr cholecystokinin B receptor affects response to substance ISO CCKBR protein affects the susceptibility to Sulpiride CTD PMID:11403953 NCBI chr 1:159,771,733...159,781,738
Ensembl chr 1:159,771,733...159,814,881 		JBrowse link
G Cd86 CD86 molecule multiple interactions ISO Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of CD86 mRNA] CTD PMID:30922767 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cish cytokine inducible SH2-containing protein increases expression
multiple interactions		 EXP Sulpiride results in increased expression of CISH mRNA
Estradiol promotes the reaction [Sulpiride results in increased expression of CISH mRNA]		 CTD PMID:18162529 NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression EXP Sulpiride results in increased expression of CYP11A1 mRNA; Sulpiride results in increased expression of CYP11A1 protein CTD PMID:21427058 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases expression
multiple interactions		 EXP Sulpiride results in decreased expression of CYP1A1 mRNA
Sulpiride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]		 CTD PMID:26466350 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases expression
multiple interactions		 EXP Sulpiride results in decreased expression of CYP1A2 mRNA
Sulpiride inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 mRNA]		 CTD PMID:26466350 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Drd2 dopamine receptor D2 affects binding
decreases activity
multiple interactions
increases expression		 ISO
EXP		 Sulpiride binds to DRD2 protein
Sulpiride results in decreased activity of DRD2 protein
[Sulpiride binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Methamphetamine
Sulpiride results in increased expression of DRD2
Sulpiride inhibits the reaction [[Norepinephrine binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]; Sulpiride inhibits the reaction [[Quinpirole binds to and results in increased activity of DRD2 protein alternative form] which results in decreased transport of Calcium]
Methamphetamine inhibits the reaction [Sulpiride binds to DRD2 protein]; Sulpiride binds to and results in decreased activity of DRD2 protein; Sulpiride inhibits the reaction [Tacrolimus affects the activity of DRD2 protein]		 CTD PMID:1351265 PMID:2891082 PMID:2901473 PMID:7644023 PMID:8032591 More... NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Fcgr2a Fc gamma receptor 2A multiple interactions ISO Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of FCGR3 mRNA] CTD PMID:30922767 NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967 		JBrowse link
G Fcgr2b Fc gamma receptor 2B multiple interactions ISO Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in increased expression of FCGR2B mRNA] CTD PMID:30922767 NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778 		JBrowse link
G Foxo1 forkhead box O1 affects localization EXP Sulpiride affects the localization of FOXO1 protein modified form CTD PMID:26466350 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Gad1 glutamate decarboxylase 1 decreases methylation
multiple interactions		 ISO Sulpiride results in decreased methylation of GAD1 promoter
Valproic Acid promotes the reaction [Sulpiride results in decreased methylation of GAD1 promoter]		 CTD PMID:18757738 NCBI chr 3:55,369,704...55,410,335
Ensembl chr 3:55,369,704...55,410,333 		JBrowse link
G Gh1 growth hormone 1 decreases expression
multiple interactions		 EXP Sulpiride results in decreased expression of GH1 protein
Benzo(a)pyrene affects the reaction [Sulpiride results in decreased expression of GH1 protein]		 CTD PMID:26466350 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions
increases expression		 EXP Sulpiride inhibits the reaction [Benzo(a)pyrene results in increased expression of HSP90AA1 mRNA]
Sulpiride results in increased expression of HSP90AA1 mRNA		 CTD PMID:26466350 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Ins1 insulin 1 multiple interactions
decreases expression		 EXP [Sulpiride co-treated with Benzo(a)pyrene] results in decreased expression of INS1 protein
Sulpiride results in decreased expression of INS1 protein		 CTD PMID:26466350 NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536 		JBrowse link
G Ins2 insulin 2 increases expression ISO Sulpiride results in increased expression of INS protein CTD PMID:16601995 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Irs1 insulin receptor substrate 1 multiple interactions
decreases expression		 EXP Sulpiride results in decreased expression of and results in increased phosphorylation of IRS1 protein
Sulpiride results in decreased expression of IRS1 mRNA		 CTD PMID:29551354 NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122 		JBrowse link
G Kcnh1 potassium voltage-gated channel subfamily H member 1 multiple interactions ISO Sulpiride binds to and results in decreased activity of KCNH1 protein CTD PMID:17982510 NCBI chr13:103,722,140...104,024,762
Ensembl chr13:103,722,245...104,024,740 		JBrowse link
G Lhb luteinizing hormone subunit beta affects secretion EXP Sulpiride affects the secretion of LHB protein CTD PMID:18162529 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Nr5a2 nuclear receptor subfamily 5, group A, member 2 increases expression EXP Sulpiride results in increased expression of NR5A2 mRNA CTD PMID:21427058 NCBI chr13:48,313,634...48,433,494
Ensembl chr13:48,316,301...48,433,326 		JBrowse link
G Prl prolactin increases abundance
increases expression
increases secretion
multiple interactions		 ISO
EXP		 Sulpiride results in increased abundance of PRL protein
Sulpiride results in increased expression of PRL mRNA; Sulpiride results in increased expression of PRL protein
Sulpiride results in increased secretion of PRL protein
Benzo(a)pyrene promotes the reaction [Sulpiride results in increased expression of PRL protein]; Sulpiride inhibits the reaction [Bromocriptine results in decreased secretion of PRL protein]; Sulpiride inhibits the reaction [Cabergoline results in decreased secretion of PRL protein]
Triptorelin Pamoate inhibits the reaction [Sulpiride results in increased abundance of PRL protein]; Verapamil inhibits the reaction [Sulpiride results in increased secretion of PRL protein]		 CTD PMID:956353 PMID:2948424 PMID:2954994 PMID:3137082 PMID:3891423 More... NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prlr prolactin receptor increases expression EXP Sulpiride results in increased expression of PRLR mRNA alternative form CTD PMID:18162529 NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718 		JBrowse link
G Reln reelin multiple interactions
decreases methylation		 ISO Valproic Acid promotes the reaction [Sulpiride results in decreased methylation of RELN promoter] CTD PMID:18757738 PMID:19110320 NCBI chr 4:12,736,177...13,162,956
Ensembl chr 4:12,736,130...13,162,211 		JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases expression EXP Sulpiride results in increased expression of SCARB1 mRNA; Sulpiride results in increased expression of SCARB1 protein CTD PMID:21427058 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of SLC18A2 protein] CTD PMID:30922767 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc22a23 solute carrier family 22, member 23 multiple interactions ISO Sulpiride inhibits the reaction [SLC22A23 protein results in increased uptake of 1-Methyl-4-phenylpyridinium analog] CTD PMID:28597291 NCBI chr17:30,544,106...30,709,790
Ensembl chr17:30,544,106...30,709,790 		JBrowse link
G Slc22a3 solute carrier family 22 member 3 increases uptake ISO SLC22A3 protein results in increased uptake of Sulpiride CTD PMID:28597291 NCBI chr 1:48,235,476...48,324,617
Ensembl chr 1:48,235,476...48,324,612 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions ISO Sulpiride inhibits the reaction [Dopamine affects the localization of SLC6A3 protein]; Sulpiride inhibits the reaction [SLC6A3 protein results in increased uptake of Dopamine]
Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of SLC6A3 protein]		 CTD PMID:20875051 PMID:30922767 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 increases expression EXP Sulpiride results in increased expression of SOCS1 mRNA CTD PMID:18162529 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression
multiple interactions		 EXP Sulpiride results in increased expression of SOCS3 mRNA
Estradiol promotes the reaction [Sulpiride results in increased expression of SOCS3 mRNA]		 CTD PMID:18162529 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787 		JBrowse link
G Srd5a1 steroid 5 alpha-reductase 1 increases expression EXP Sulpiride results in increased expression of SRD5A1 mRNA CTD PMID:18978642 NCBI chr 1:33,686,069...33,720,468
Ensembl chr 1:33,686,391...33,720,461 		JBrowse link
G Srd5a2 steroid 5 alpha-reductase 2 increases expression EXP Sulpiride results in increased expression of SRD5A2 mRNA CTD PMID:18978642 NCBI chr 6:21,426,225...21,465,727
Ensembl chr 6:21,426,215...21,462,112 		JBrowse link
G Star steroidogenic acute regulatory protein increases expression EXP Sulpiride results in increased expression of STAR mRNA; Sulpiride results in increased expression of STAR protein CTD PMID:21427058 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
increases activity		 EXP
ISO		 Sulpiride inhibits the reaction [Dopamine results in decreased activity of TH protein]; Sulpiride inhibits the reaction [Rotenone results in decreased expression of TH protein]
Sulpiride inhibits the reaction [1-(2-thienyl)-2-(methylamino)propane results in decreased expression of TH protein]
Sulpiride results in increased activity of TH protein		 CTD PMID:2884129 PMID:18289173 PMID:30922767 NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
tetrabenazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc18a1 solute carrier family 18 member A1 multiple interactions ISO Tetrabenazine inhibits the reaction [SLC18A1 protein results in increased uptake of Serotonin] CTD PMID:8245983 NCBI chr16:20,653,268...20,687,051
Ensembl chr16:20,653,508...20,687,051 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 affects binding
decreases activity
multiple interactions		 ISO
EXP		 Tetrabenazine binds to SLC18A2 protein
Tetrabenazine binds to Slc8a2 protein
Tetrabenazine results in decreased activity of SLC18A2 protein
Tetrabenazine inhibits the reaction [SLC18A2 protein results in increased uptake of Serotonin]		 CTD
RGD		 PMID:1438304 PMID:7912402 PMID:15475732 PMID:19616025 PMID:33378168 More... RGD:5130957 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
thiethylperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO [Thiethylperazine results in increased activity of ABCC1 protein] which results in increased export of APP protein CTD PMID:21881209 NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [Thiethylperazine results in increased activity of ABCC1 protein] which results in increased export of APP protein CTD PMID:21881209 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
thioridazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ap1s1 adaptor related protein complex 1 subunit sigma 1 decreases expression ISO Thioridazine results in decreased expression of AP1S1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr12:19,625,267...19,635,792
Ensembl chr12:19,625,332...19,756,713 		JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO Thioridazine results in increased expression of ASAH1 mRNA CTD PMID:17175557 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression ISO Thioridazine results in increased expression of ASNS mRNA CTD PMID:17175557 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Casp3 caspase 3 increases activity ISO Thioridazine results in increased activity of CASP3 protein CTD PMID:21035837 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Thioridazine results in decreased expression of CCND1 protein CTD PMID:21035837 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdc25a cell division cycle 25A increases phosphorylation ISO Thioridazine results in increased phosphorylation of CDC25A protein CTD PMID:21035837 NCBI chr 8:109,864,356...109,882,734
Ensembl chr 8:109,864,478...109,882,701 		JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO Thioridazine results in decreased expression of CDK4 protein CTD PMID:21035837 NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Thioridazine results in increased expression of CDKN1A protein CTD PMID:21035837 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases expression ISO Thioridazine results in increased expression of CDKN2A protein CTD PMID:21035837 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Ces1d carboxylesterase 1D multiple interactions ISO Thioridazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate]; Thioridazine inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Crh corticotropin releasing hormone decreases expression ISO Thioridazine results in decreased expression of CRH mRNA CTD PMID:16205782 NCBI chr 2:102,143,055...102,144,919
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Thioridazine; CYP1A2 protein results in increased metabolism of and results in increased activity of Thioridazine CTD PMID:19482014 PMID:23397584 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2c6 cytochrome P450, family 2, subfamily C, polypeptide 6 multiple interactions
decreases activity		 ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Thioridazine
Thioridazine results in decreased activity of CYP2C19 protein		 CTD PMID:15135088 PMID:23397584 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Thioridazine; CYP2D6 protein results in increased metabolism of and results in increased activity of Thioridazine CTD PMID:19482014 PMID:23397584 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Thioridazine results in decreased activity of CYP2E1 protein CTD PMID:15135088 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions
decreases activity		 ISO [CYP1A2 protein co-treated with CYP2C9 protein co-treated with CYP3A4 protein co-treated with CYP2D6 protein co-treated with CYP2C19 protein] affects the susceptibility to Thioridazine
Thioridazine results in decreased activity of CYP3A4 protein		 CTD PMID:15135088 PMID:23397584 NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Depp1 DEPP autophagy regulator 1 increases expression ISO Thioridazine results in increased expression of DEPP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 4:149,910,794...149,913,013
Ensembl chr 4:149,910,779...149,914,542 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 decreases phosphorylation ISO Thioridazine results in decreased phosphorylation of EIF4EBP1 protein CTD PMID:21035837 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Fabp1 fatty acid binding protein 1 increases expression ISO Thioridazine results in increased expression of FABP1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788 		JBrowse link
G Fndc4 fibronectin type III domain containing 4 increases expression ISO Thioridazine results in increased expression of FNDC4 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:25,077,155...25,080,812
Ensembl chr 6:25,077,349...25,080,675 		JBrowse link
G Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 increases expression ISO Thioridazine results in increased expression of GDPD3 mRNA CTD PMID:17175557 NCBI chr 1:181,373,505...181,383,063
Ensembl chr 1:181,366,626...181,383,063 		JBrowse link
G Hpn hepsin increases expression ISO Thioridazine results in increased expression of HPN mRNA CTD PMID:15342952 NCBI chr 1:86,337,085...86,352,785
Ensembl chr 1:86,337,087...86,352,811 		JBrowse link
G Inhbe inhibin subunit beta E increases expression ISO Thioridazine results in increased expression of INHBE mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions
decreases activity		 ISO Thioridazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium]
Thioridazine results in decreased activity of KCNH2 protein		 CTD PMID:15671647 PMID:16278312 PMID:21158687 PMID:24052561 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Lss lanosterol synthase increases expression ISO Thioridazine results in increased expression of LSS mRNA CTD PMID:15342952 PMID:17175557 NCBI chr20:12,091,138...12,118,858
Ensembl chr20:12,092,774...12,118,762 		JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 increases expression ISO Thioridazine results in increased expression of NR0B2 mRNA CTD PMID:17175557 NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609 		JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Thioridazine results in increased expression of NUPR1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281 		JBrowse link
G Phyh phytanoyl-CoA 2-hydroxylase increases expression ISO Thioridazine results in increased expression of PHYH mRNA CTD PMID:15342952 NCBI chr17:73,329,461...73,346,359
Ensembl chr17:73,329,082...73,346,409 		JBrowse link
G Prl prolactin increases expression ISO Thioridazine results in increased expression of PRL protein CTD PMID:4065553 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Serpina3n serine (or cysteine) peptidase inhibitor, clade A, member 3N increases expression ISO Thioridazine results in increased expression of SERPINA3 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Thioridazine inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 decreases expression ISO Thioridazine results in decreased expression of SLC2A3 mRNA CTD PMID:15342952 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Tagln transgelin decreases expression ISO Thioridazine results in decreased expression of TAGLN mRNA CTD PMID:15342952 PMID:17175557 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tp53 tumor protein p53 affects activity ISO Thioridazine affects the activity of TP53 protein CTD PMID:35435491 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Wipi1 WD repeat domain, phosphoinositide interacting 1 increases expression ISO Thioridazine results in increased expression of WIPI1 mRNA CTD PMID:15342952 PMID:17175557 NCBI chr10:94,542,946...94,580,174
Ensembl chr10:94,542,946...94,579,846 		JBrowse link
tianeptine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP tianeptine results in increased expression of ABCC2 mRNA CTD PMID:27765674 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 increases expression EXP tianeptine results in increased expression of ABCG5 mRNA CTD PMID:27765674 NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563 		JBrowse link
G Abcg8 ATP binding cassette subfamily G member 8 increases expression EXP tianeptine results in increased expression of ABCG8 mRNA CTD PMID:27765674 NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912 		JBrowse link
G Angptl3 angiopoietin-like 3 decreases expression ISO tianeptine results in decreased expression of ANGPTL3 mRNA CTD PMID:27089845 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957 		JBrowse link
G Cat catalase multiple interactions EXP tianeptine inhibits the reaction [Indomethacin results in increased activity of CAT protein] CTD PMID:19497431 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cnr2 cannabinoid receptor 2 increases expression EXP tianeptine results in increased expression of CNR2 protein CTD PMID:28866072 NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548 		JBrowse link
G Drd2 dopamine receptor D2 decreases expression EXP tianeptine results in decreased expression of DRD2 mRNA CTD PMID:11981225 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Igfbp1 insulin-like growth factor binding protein 1 increases expression ISO tianeptine results in increased expression of IGFBP1 mRNA CTD PMID:27089845 NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482 		JBrowse link
G Mpo myeloperoxidase multiple interactions EXP tianeptine inhibits the reaction [Indomethacin results in increased activity of MPO protein] CTD PMID:19497431 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Oprm1 opioid receptor, mu 1 increases activity ISO tianeptine results in increased activity of OPRM1 protein CTD PMID:32734307 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 decreases expression EXP tianeptine results in decreased expression of SLC10A1 mRNA CTD PMID:27765674 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc6a4 solute carrier family 6 member 4 multiple interactions ISO tianeptine binds to and results in decreased activity of SLC6A4 protein CTD PMID:16272152 NCBI chr10:61,824,208...61,858,924
Ensembl chr10:61,826,123...61,858,384 		JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO tianeptine results in increased expression of SREBF1 mRNA CTD PMID:27089845 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650 		JBrowse link
trifluoperazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases activity ISO Trifluoperazine results in increased activity of ABCB1 protein CTD PMID:2900677 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Ache acetylcholinesterase multiple interactions
increases activity
decreases expression		 EXP
ISO		 energostim inhibits the reaction [Trifluoperazine results in decreased expression of ACHE protein]
Trifluoperazine results in increased activity of ACHE protein		 CTD PMID:15232633 PMID:29614332 NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of AKT1 protein] CTD PMID:19233221 PMID:21544200 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Atp6v1h ATPase H+ transporting V1 subunit H multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA CTD PMID:28366621 NCBI chr 5:14,379,029...14,484,703
Ensembl chr 5:14,378,257...14,537,962 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Trifluoperazine results in increased expression of BAX protein CTD PMID:21475906 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Trifluoperazine results in decreased expression of BCL2 protein CTD PMID:21475906 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Camk2a calcium/calmodulin-dependent protein kinase II alpha multiple interactions EXP Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of CAMK2A protein] CTD PMID:19233221 NCBI chr18:54,378,642...54,441,120
Ensembl chr18:54,378,784...54,438,994 		JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein] CTD PMID:21544200 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Cd44 CD44 molecule multiple interactions ISO Trifluoperazine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD44 protein] CTD PMID:9929743 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein] CTD PMID:21544200 NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984 		JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 increases oxidation ISO FMO2 protein results in increased oxidation of Trifluoperazine CTD PMID:26062974 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308 		JBrowse link
G Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 multiple interactions ISO Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:15627515 NCBI chr20:1,464,534...1,494,114
Ensembl chr20:1,464,534...1,493,994 		JBrowse link
G Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 multiple interactions ISO Trifluoperazine inhibits the reaction [2,6-di-tert-butyl-4-(3-hydroxy-2,2-dimethylpropyl)phenol promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABBR1 protein binds to GABBR2 protein]]] CTD PMID:15627515 NCBI chr 5:60,947,517...61,288,104
Ensembl chr 5:60,947,526...61,288,104 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha decreases expression ISO Trifluoperazine results in decreased expression of HIF1A protein CTD PMID:18822394 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Il12b interleukin 12B multiple interactions ISO Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IL12B protein] CTD PMID:16249388 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 multiple interactions ISO Trifluoperazine inhibits the reaction [KCNH2 protein results in increased transport of Thallium] CTD PMID:21158687 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Kcnn2 potassium calcium-activated channel subfamily N member 2 decreases activity EXP Trifluoperazine results in decreased activity of KCNN2 protein CTD PMID:10915830 NCBI chr18:37,817,966...38,258,347
Ensembl chr18:37,817,957...38,258,347 		JBrowse link
G Lamp1 lysosomal-associated membrane protein 1 multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA CTD PMID:28366621 NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK1 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Trifluoperazine inhibits the reaction [Dinoprost results in increased activity of MAPK1 protein] CTD PMID:11914123 PMID:21544200 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 multiple interactions ISO
EXP		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK14 protein] CTD PMID:21544200 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [[Norepinephrine co-treated with Timolol] results in increased activity of MAPK3 protein]; Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Trifluoperazine inhibits the reaction [Dinoprost results in increased activity of MAPK3 protein] CTD PMID:11914123 PMID:21544200 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO
EXP		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK8 protein] CTD PMID:21544200 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions ISO
EXP		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK9 protein] CTD PMID:21544200 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mt1 metallothionein 1 increases expression EXP Trifluoperazine results in increased expression of MT1A mRNA CTD PMID:8128501 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
decreases phosphorylation		 EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MTOR protein]
Trifluoperazine analog results in decreased phosphorylation of MTOR protein
STON2 protein inhibits the reaction [Trifluoperazine analog results in decreased phosphorylation of MTOR protein]		 CTD PMID:21544200 PMID:36702439 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Myl9 myosin light chain 9 multiple interactions EXP Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MYL9 protein]; Trifluoperazine inhibits the reaction [Ionomycin results in increased phosphorylation of MYL9 protein] CTD PMID:19233221 NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333 		JBrowse link
G Nefl neurofilament light chain multiple interactions EXP Trifluoperazine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA] CTD PMID:31969611 NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases activity ISO Trifluoperazine results in decreased activity of NR3C1 protein CTD PMID:7887964 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] CTD PMID:21544200 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pink1 PTEN induced kinase 1 multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of ATP6V1H mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of LAMP1 mRNA; [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase affects localization
multiple interactions		 ISO Trifluoperazine affects the localization of PRKN protein
PRKN protein affects the reaction [Trifluoperazine affects the localization of PRKN protein]		 CTD PMID:28366621 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Prl prolactin increases expression ISO Trifluoperazine results in increased expression of PRL protein CTD PMID:2136057 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO Trifluoperazine inhibits the reaction [Hydrogen Peroxide results in decreased localization of REL protein] CTD PMID:16249388 NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions EXP
ISO		 Trifluoperazine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein] CTD PMID:21544200 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Slc5a6 solute carrier family 5 member 6 multiple interactions ISO Trifluoperazine inhibits the reaction [SLC5A6 protein results in increased transport of Biotin] CTD PMID:15561972 NCBI chr 6:25,319,187...25,331,713
Ensembl chr 6:25,320,442...25,331,712 		JBrowse link
G Ston2 stonin 2 decreases expression
multiple interactions		 ISO Trifluoperazine analog results in decreased expression of STON2 protein
STON2 protein inhibits the reaction [Trifluoperazine analog results in decreased phosphorylation of MTOR protein]		 CTD PMID:36702439 NCBI chr 6:110,567,485...110,676,376
Ensembl chr 6:110,567,485...110,676,376 		JBrowse link
G Tfeb transcription factor EB multiple interactions ISO [PINK1 protein affects the susceptibility to [Trifluoperazine co-treated with Antimycin A co-treated with oligomycin A]] which affects the expression of TFEB mRNA; Trifluoperazine affects the reaction [PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of TFEB protein]] CTD PMID:28366621 NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases activity ISO Trifluoperazine results in decreased activity of TNFSF11 CTD PMID:21869564 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase family 1 member A5 increases glucuronidation
multiple interactions
increases activity		 ISO UGT1A4 protein results in increased glucuronidation of Trifluoperazine
Finasteride inhibits the reaction [UGT1A4 protein results in increased glucuronidation of Trifluoperazine]; hecogenin inhibits the reaction [UGT1A4 protein results in increased glucuronidation of Trifluoperazine]; licochalcone A inhibits the reaction [Trifluoperazine results in increased activity of UGT1A4 protein]; Trifluoperazine inhibits the reaction [UGT1A4 protein results in increased glucuronidation of afloqualone]		 CTD PMID:15135306 PMID:15475412 PMID:25393417 PMID:25448279 PMID:26875642 More... NCBI chr 9:88,762,250...88,808,465
Ensembl chr 9:88,713,184...88,808,465 		JBrowse link
triflupromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Triflupromazine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
ziprasidone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alb albumin multiple interactions
affects binding		 EXP
ISO		 ziprasidone results in decreased expression of and results in increased reduction of ALB protein
ziprasidone binds to ALB protein
[ziprasidone results in increased reduction of Cysteine] which results in increased activity of ALB protein; stearic acid inhibits the reaction [ziprasidone binds to ALB protein]		 CTD PMID:31400341 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Cat catalase increases expression EXP ziprasidone results in increased expression of CAT mRNA CTD PMID:32937854 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase increases expression ISO ziprasidone results in increased expression of HMGCR mRNA CTD PMID:17052361 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703 		JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 increases expression ISO ziprasidone results in increased expression of HMGCS1 mRNA CTD PMID:17052361 NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP ziprasidone results in increased expression of HMOX1 mRNA CTD PMID:32937854 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A multiple interactions EXP [N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridinyl)cyclohexanecarboxamide binds to and results in decreased activity of HTR1A protein] which results in increased susceptibility to ziprasidone CTD PMID:15996562 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A multiple interactions ISO ziprasidone inhibits the reaction [Ketanserin binds to HTR2A protein] CTD PMID:16314884 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO ziprasidone results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression EXP ziprasidone results in increased expression of NQO1 mRNA CTD PMID:32937854 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Sc5d sterol-C5-desaturase increases expression ISO ziprasidone results in increased expression of SC5D mRNA CTD PMID:17052361 NCBI chr 8:42,629,649...42,641,257
Ensembl chr 8:42,632,672...42,641,273 		JBrowse link
G Slc22a5 solute carrier family 22 member 5 multiple interactions ISO ziprasidone inhibits the reaction [SLC22A5 protein results in increased uptake of Carnitine] CTD PMID:30465787 NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309 		JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO ziprasidone results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228 		JBrowse link
zotepine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin decreases expression ISO zotepine results in decreased expression of PRL protein CTD PMID:18063941 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19811
    role 19818
      application 19630
        pharmaceutical 19503
          drug 19471
            central nervous system drug 16761
              central nervous system depressant 16278
                tranquilizing drug 14902
                  antipsychotic agent 1413
                    (S)-(-)-sulpiride 0
                    LY 379268 1
                    LY404039 0
                    N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride 1
                    alstonine 0
                    azaperone 1
                    benzquinamide + 0
                    chlormezanone + 0
                    dapiprazole 0
                    etazolate 2
                    ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate 0
                    first generation antipsychotic + 830
                    gevotroline 0
                    gevotroline hydrochloride 0
                    loxapine + 9
                    methiothepin 7
                    methiothepin maleate 0
                    pavinetant 0
                    pimavanserin 0
                    pimavanserin tartrate 0
                    ritanserin 7
                    second generation antipsychotic + 969
                    spiperone 13
                    sulpiride + 48
                    tetrabenazine 2
                    ulotaront 0
                    ziprasidone + 12
paths to the root