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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:antipsychotic agent
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Accession:CHEBI:35476 term browser browse the term
Definition:Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
Synonyms:related_synonym: Neuroleptikum;   antipsychotic agents;   antipsychotic drug;   antipsychotic drugs;   antipsychotics;   antipsychotiques;   grosser Tranquilizer;   major tranquilizers;   major tranquilizing agents;   neuroleptic;   neuroleptic agents;   neuroleptics;   neuroleptique;   neuroleptiques


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chlorpromazine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAO D-amino acid oxidase decreases activity EXP Chlorpromazine results in decreased activity of DAO protein CTD PMID:18615285 NCBI chr14:41,931,549...41,950,628
Ensembl chr14:41,931,541...41,950,633 		JBrowse link
G FMO1 flavin containing dimethylaniline monoxygenase 1 increases oxidation EXP FMO1 protein results in increased oxidation of Chlorpromazine CTD PMID:6439199 NCBI chr 9:63,860,957...63,895,086
Ensembl chr 9:63,868,064...63,895,076 		JBrowse link
haloperidol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EDN1 endothelin 1 multiple interactions EXP Haloperidol inhibits the reaction [Cocaine results in increased expression of EDN1 protein] CTD PMID:9714087 NCBI chr 7:8,752,018...8,758,354
Ensembl chr 7:8,751,695...8,758,348 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5052
    role 5044
      application 863
        pharmaceutical 723
          drug 713
            central nervous system drug 162
              central nervous system depressant 159
                tranquilizing drug 23
                  antipsychotic agent 3
                    (S)-(-)-sulpiride 0
                    LY 379268 0
                    LY404039 0
                    N-\{2-[4-methoxy-3-(2-phenylethoxy)phenyl]ethyl\}-N-propylpropan-1-amine hydrochloride 0
                    alstonine 0
                    azaperone 0
                    benzquinamide + 0
                    chlormezanone + 0
                    dapiprazole 0
                    etazolate 0
                    ethyl (5Z,8Z,11Z,14Z,17Z)-icosapentaenoate 0
                    first generation antipsychotic + 3
                    gevotroline 0
                    gevotroline hydrochloride 0
                    loxapine + 0
                    methiothepin 0
                    methiothepin maleate 0
                    pavinetant 0
                    pimavanserin 0
                    pimavanserin tartrate 0
                    ritanserin 0
                    second generation antipsychotic + 0
                    spiperone 0
                    sulpiride + 0
                    tetrabenazine 0
                    ulotaront 0
                    ziprasidone + 0
paths to the root