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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:anthelminthic drug
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Accession:CHEBI:35443 term browser browse the term
Definition:Substance intended to kill parasitic worms (helminths).
Synonyms:exact_synonym: anthelminthic
 related_synonym: anthelminthics;   anthelmintic;   anthelmintics;   antihelminth;   antihelmintico;   vermifuge


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2'-(4-ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-2,5'-bibenzimidazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP binding cassette subfamily B member 11 multiple interactions
decreases activity
ISO bisbenzimide ethoxide trihydrochloride inhibits the reaction [ABCB11 protein results in increased transport of Taurocholic Acid]
bisbenzimide ethoxide trihydrochloride results in decreased activity of ABCB11 protein
CTD PMID:24014644 NCBI chr 3:55,480,024...55,587,946
Ensembl chr 3:55,480,024...55,587,946
JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases transport
multiple interactions
ISO ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride
ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride
abamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
abamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
CTD PMID:25865432 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
increases transport
ISO abamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; emamectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride] CTD PMID:25865432 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 decreases abundance
decreases export
decreases activity
multiple interactions
increases export
increases transport
ISO ABCG2 protein results in decreased abundance of bisbenzimide ethoxide trihydrochloride
ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride
bisbenzimide ethoxide trihydrochloride results in decreased activity of ABCG2 protein
2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; 3-(6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7,12,12a-octahydropyrazino(1',2'-1,6)pyrido(3,4-b)indol-3-yl)propionic acid tert-butyl ester inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; [MYC protein results in increased expression of ABCG2 protein] which results in increased export of bisbenzimide ethoxide trihydrochloride; Cimetidine inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Cyclosporine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; danofloxacin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Genistein inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Genistein promotes the reaction [ABCG2 protein polymorphism results in decreased export of bisbenzimide ethoxide trihydrochloride]; Methotrexate inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Nitrofurantoin inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; Reserpine inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Tobacco Smoke Pollution inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; tryptoquivaline inhibits the reaction [ABCG2 protein results in increased export of bisbenzimide ethoxide trihydrochloride]; verlukast inhibits the reaction [ABCG2 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
CTD PMID:12869632 PMID:19239227 PMID:26850786 PMID:26907376 PMID:27450509 PMID:27475308 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases export ISO KEAP1 protein results in decreased export of bisbenzimide ethoxide trihydrochloride CTD PMID:25841332 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [MYC protein results in increased expression of ABCG2 protein] which results in increased export of bisbenzimide ethoxide trihydrochloride CTD PMID:19239227 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
2-naphthol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 affects sulfation ISO ABCC1 protein affects the sulfation of 2-naphthol CTD PMID:14742140 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO [2-naphthol binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ar androgen receptor multiple interactions EXP 2-naphthol inhibits the reaction [Metribolone binds to AR protein] CTD PMID:3695475 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Ces1d carboxylesterase 1D affects metabolic processing ISO CES1 protein affects the metabolism of 2-naphthol CTD PMID:12837533 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases abundance ISO CYP1A1 protein results in increased abundance of 2-naphthol CTD PMID:16243959 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases abundance
affects binding
decreases activity
ISO CYP1A2 protein results in increased abundance of 2-naphthol
2-naphthol binds to CYP1A2 protein
2-naphthol results in decreased activity of CYP1A2 protein
CTD PMID:15916432 PMID:16243959 PMID:32278787 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions ISO [2-naphthol binds to and results in increased activity of AHR protein] which results in increased expression of CYP1B1 mRNA CTD PMID:27837168 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases abundance ISO CYP2B6 protein results in increased abundance of 2-naphthol CTD PMID:16243959 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases abundance ISO CYP2E1 protein results in increased abundance of 2-naphthol CTD PMID:16243959 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases abundance ISO CYP3A4 protein results in increased abundance of 2-naphthol CTD PMID:16243959 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Sult4a1 sulfotransferase family 4A, member 1 increases metabolic processing ISO SULT4A1 protein results in increased metabolism of 2-naphthol CTD PMID:12039030 NCBI chr 7:124,958,546...124,982,602
Ensembl chr 7:124,958,546...124,982,566
JBrowse link
G Thrb thyroid hormone receptor beta multiple interactions ISO 2-naphthol binds to and results in decreased activity of THRB protein CTD PMID:18584933 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Ugt2b15 UDP glucuronosyltransferase family 2 member B15 increases metabolic processing EXP UGT2B15 protein results in increased metabolism of 2-naphthol CTD PMID:7574722 NCBI chr14:22,375,428...22,486,291
Ensembl chr14:22,375,955...22,534,720
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases glucuronidation EXP UGT2B1 protein results in increased glucuronidation of 2-naphthol CTD PMID:8302279 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link
albendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy7 adenylate cyclase 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ADCY7 mRNA CTD PMID:16861626 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of ARL4C mRNA CTD PMID:16861626 NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of BAG3 mRNA CTD PMID:16861626 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Albendazole results in increased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCL3 protein CTD PMID:16861626 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CCR7 mRNA CTD PMID:16861626 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCT3 mRNA CTD PMID:16861626 NCBI chr 2:187,669,051...187,693,610
Ensembl chr 2:187,668,796...187,693,610
JBrowse link
G Cd86 CD86 molecule multiple interactions ISO [Albendazole co-treated with CYP3A4 protein] results in increased expression of CD86 protein CTD PMID:22785256 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CTSL mRNA CTD PMID:16861626 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
increases expression
ISO Albendazole results in increased activity of CYP1A1 promoter; Albendazole results in increased activity of CYP1A1 protein
Albendazole results in increased expression of CYP1A1 mRNA
CTD PMID:12451431 PMID:16714371 PMID:18502397 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression
affects metabolic processing
ISO Albendazole results in increased expression of CYP1A2 mRNA
CYP1A2 protein affects the metabolism of Albendazole
CTD PMID:12451431 PMID:12920490 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO
EXP
[Albendazole co-treated with CYP3A4 protein] results in increased expression of CD86 protein; [Albendazole co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein
[SOD2 co-treated with CYP3A4] affects the susceptibility to Albendazole
CTD PMID:19501153 PMID:22785256 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DNAJB1 mRNA CTD PMID:16861626 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DPYSL2 mRNA CTD PMID:16861626 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of GEM mRNA CTD PMID:16861626 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Gpr183 G protein-coupled receptor 183 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of GPR183 mRNA CTD PMID:16861626 NCBI chr15:108,364,701...108,376,221
Ensembl chr15:108,364,701...108,376,221
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AA1 mRNA CTD PMID:16861626 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AB1 mRNA CTD PMID:16861626 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA4 mRNA CTD PMID:16861626 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA8 mRNA CTD PMID:16861626 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPD1 mRNA CTD PMID:16861626 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPE1 mRNA CTD PMID:16861626 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPH1 mRNA CTD PMID:16861626 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Albendazole co-treated with CYP3A4 protein] results in increased expression of ICAM1 protein CTD PMID:22785256 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL10 protein CTD PMID:16861626 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein CTD PMID:16861626 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1R1 mRNA CTD PMID:16861626 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO Albendazole results in increased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of MAP3K8 mRNA CTD PMID:16861626 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Albendazole results in decreased expression of MAPT mRNA; Albendazole results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Albendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPID mRNA CTD PMID:16861626 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Ppif peptidylprolyl isomerase F multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPIF mRNA CTD PMID:16861626 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of PTGES3 mRNA CTD PMID:16861626 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G RT1-DMb RT1 class II, locus DMb affects expression ISO Albendazole affects the expression of HLA-DMB mRNA CTD PMID:25811541 NCBI chr20:3,945,383...3,952,838
Ensembl chr20:5,227,045...5,234,290
Ensembl chr20:5,227,045...5,234,290
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of SKAP2 mRNA CTD PMID:16861626 NCBI chr 4:81,816,778...81,968,832
Ensembl chr 4:81,818,569...81,968,832
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [SOD2 co-treated with CYP3A4] affects the susceptibility to Albendazole CTD PMID:19501153 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of SPHK1 mRNA CTD PMID:16861626 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G St13 ST13, Hsp70 interacting protein multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ST13 mRNA CTD PMID:16861626 NCBI chr 7:122,585,770...122,635,731
Ensembl chr 7:122,585,771...122,635,731
JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of TCP1 mRNA CTD PMID:16861626 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TGIF1 mRNA CTD PMID:16861626 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases secretion
ISO U 0126 inhibits the reaction [Albendazole results in increased secretion of TNF protein] CTD PMID:20848085 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TSC22D1 mRNA CTD PMID:16861626 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Albendazole results in increased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
albendazole S-oxide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 affects transport ISO ABCG2 protein affects the transport of albendazole sulfoxide CTD PMID:15703302 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO albendazole sulfoxide inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
alpha-santonin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions ISO [Santonin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:25455453 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO [Santonin results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
ascaridole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ercc6 ERCC excision repair 6, chromatin remodeling factor affects response to substance ISO ERCC6 protein affects the susceptibility to ascaridole CTD PMID:22280988 NCBI chr16:8,734,028...8,804,610
Ensembl chr16:8,734,035...8,804,610
JBrowse link
G Xpc XPC complex subunit, DNA damage recognition and repair factor affects response to substance ISO XPC protein affects the susceptibility to ascaridole CTD PMID:22280988 NCBI chr 4:123,134,457...123,161,985
Ensembl chr 4:123,134,457...123,161,985
JBrowse link
benomyl term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam33 ADAM metallopeptidase domain 33 multiple interactions
increases expression
ISO ORMDL3 protein affects the reaction [Benomyl results in increased expression of ADAM33 protein] CTD PMID:27784618 NCBI chr 3:123,595,018...123,607,549
Ensembl chr 3:123,595,560...123,607,352
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity ISO
EXP
Benomyl metabolite results in decreased activity of ALDH2 protein; Benomyl results in decreased activity of ALDH2 protein CTD PMID:9585485 PMID:10513990 PMID:11142365 PMID:15331769 PMID:17010440 NCBI chr12:40,466,418...40,498,813
Ensembl chr12:40,466,495...40,498,752
JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases activity EXP Benomyl results in decreased activity of ALDH5A1 protein CTD PMID:17010440 NCBI chr17:42,133,076...42,159,413
Ensembl chr17:42,133,076...42,159,413
JBrowse link
G Ampd3 adenosine monophosphate deaminase 3 decreases expression EXP Benomyl results in decreased expression of AMPD3 mRNA CTD PMID:15885261 NCBI chr 1:175,585,301...175,630,479
Ensembl chr 1:175,586,097...175,630,467
JBrowse link
G Ar androgen receptor multiple interactions ISO Benomyl inhibits the reaction [Dihydrotestosterone affects the localization of and results in increased phosphorylation of AR protein] CTD PMID:25324206 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO Benomyl inhibits the reaction [BCL2 protein binds to BAX protein] CTD PMID:16903866 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases phosphorylation
ISO Benomyl inhibits the reaction [BCL2 protein binds to BAX protein]
Benomyl results in increased phosphorylation of BCL2 protein
CTD PMID:16903866 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bub1b BUB1 mitotic checkpoint serine/threonine kinase B increases expression ISO Benomyl results in increased expression of BUB1B protein CTD PMID:16903866 NCBI chr 3:110,367,949...110,420,471
Ensembl chr 3:110,367,939...110,420,458
JBrowse link
G Car2 carbonic anhydrase 2 increases expression EXP Benomyl results in increased expression of CA2 mRNA CTD PMID:15885261 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression
multiple interactions
ISO Benomyl results in increased expression of CCL17 mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of CCL17 mRNA]
CTD PMID:27784618 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccnb1 cyclin B1 increases response to substance ISO CCNB1 protein results in increased susceptibility to Benomyl CTD PMID:11960377 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnb2 cyclin B2 increases response to substance ISO CCNB2 protein results in increased susceptibility to Benomyl CTD PMID:11960377 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Cd38 CD38 molecule decreases expression EXP Benomyl results in decreased expression of CD38 mRNA CTD PMID:15885261 NCBI chr14:71,714,768...71,754,990
Ensembl chr14:71,715,269...71,754,672
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO Benomyl results in decreased expression of CYP17A1 mRNA
Benomyl results in decreased expression of and results in decreased activity of CYP17A1 protein
CTD PMID:25324206 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
ISO Benomyl results in increased activity of CYP19A1 protein
Benomyl results in increased expression of CYP19A1 mRNA
CTD PMID:14691014 PMID:25543211 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of DDIT3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of DDIT3 protein] CTD PMID:27784618 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 increases expression
multiple interactions
ISO Benomyl results in increased expression of EIF2AK3 protein
Acetylcysteine inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]
CTD PMID:27784618 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of ERN1 protein] CTD PMID:27784618 NCBI chr10:94,588,555...94,682,072
Ensembl chr10:94,588,555...94,681,914
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
ISO Benomyl binds to and results in increased activity of ESR1 protein; Benomyl inhibits the reaction [Estradiol binds to ESR1 protein]
Benomyl binds to ESR1 protein
CTD PMID:14579009 PMID:16626760 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fgfr4 fibroblast growth factor receptor 4 increases expression EXP Benomyl results in increased expression of FGFR4 mRNA CTD PMID:15885261 NCBI chr17:9,990,072...10,004,339
Ensembl chr17:9,990,078...10,004,321
JBrowse link
G Gipc1 GIPC PDZ domain containing family, member 1 increases expression EXP Benomyl results in increased expression of GIPC1 mRNA CTD PMID:15885261 NCBI chr19:24,786,604...24,798,231
Ensembl chr19:24,786,628...24,798,233
JBrowse link
G Glyat glycine-N-acyltransferase increases expression EXP Benomyl results in increased expression of GLYAT mRNA CTD PMID:15885261 NCBI chr 1:229,060,125...229,081,113
Ensembl chr 1:229,063,714...229,080,410
JBrowse link
G Hdac1 histone deacetylase 1 decreases activity ISO Benomyl results in decreased activity of HDAC1 protein CTD PMID:25543211 NCBI chr 5:147,716,664...147,743,723
Ensembl chr 5:147,716,664...147,743,723
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions
ISO Benomyl results in increased expression of HSPA5 protein
Acetylcysteine inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]
CTD PMID:27784618 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 increases expression EXP Benomyl results in increased expression of HSPB1 mRNA CTD PMID:15885261 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Benomyl inhibits the reaction [Lipopolysaccharides results in increased expression of IFNB1 mRNA] CTD PMID:18177342 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO Benomyl results in decreased expression of ITGA5 mRNA CTD PMID:25530041 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO Benomyl results in decreased expression of ITGB1 mRNA CTD PMID:25530041 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression
multiple interactions
increases expression
ISO Benomyl results in decreased expression of MMP2 mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of MMP2 protein]
CTD PMID:25530041 PMID:27784618 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression EXP
ISO
Benomyl results in decreased expression of MMP9 protein
Benomyl results in decreased expression of MMP9 mRNA
CTD PMID:10026946 PMID:25530041 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mmrn1 multimerin 1 increases expression EXP Benomyl results in increased expression of MMRN1 mRNA CTD PMID:15885261 NCBI chr 4:90,977,537...91,038,747
Ensembl chr 4:90,990,088...91,038,748
JBrowse link
G Msmb microseminoprotein, beta increases expression EXP Benomyl results in increased expression of MSMB mRNA CTD PMID:15885261 NCBI chr16:8,280,275...8,300,853
Ensembl chr16:8,280,275...8,300,852
JBrowse link
G Mt2A metallothionein 2A increases expression EXP Benomyl results in increased expression of MT2A mRNA CTD PMID:15885261 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Benomyl inhibits the reaction [Lipopolysaccharides results in increased activity of NFKB1 protein] CTD PMID:17015962 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Benomyl inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Olr1346 olfactory receptor 1346 increases expression EXP Benomyl results in increased expression of OLR1346 mRNA CTD PMID:15885261 NCBI chr 9:99,720,856...99,721,827
Ensembl chr 9:99,720,856...99,721,827
JBrowse link
G Olr1700 olfactory receptor 1700 increases expression EXP Benomyl results in increased expression of OLR1700 mRNA CTD PMID:15885261 NCBI chr20:1,089,163...1,090,128
Ensembl chr20:1,098,343...1,099,336
JBrowse link
G Olr857 olfactory receptor 857 increases expression EXP Benomyl results in increased expression of OLR857 mRNA CTD PMID:15885261 NCBI chr 5:137,738,298...137,739,246
Ensembl chr 5:137,738,298...137,739,246
Ensembl chr 5:137,738,298...137,739,246
JBrowse link
G Ormdl3 ORMDL sphingolipid biosynthesis regulator 3 multiple interactions
increases expression
ISO Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ORMDL3 protein]; MitoTEMPO inhibits the reaction [Benomyl results in increased expression of ORMDL3 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of ADAM33 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of CCL17 mRNA]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of CXCL8 mRNA]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of MMP2 protein]; ORMDL3 protein affects the reaction [Benomyl results in increased expression of TSLP mRNA] CTD PMID:27784618 NCBI chr10:86,545,910...86,554,478
Ensembl chr10:86,547,339...86,554,478
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases cleavage ISO Benomyl results in increased cleavage of PARP1 protein CTD PMID:16903866 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO Benomyl results in decreased expression of PLAU mRNA CTD PMID:25530041 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP Benomyl results in decreased expression of SCD1 mRNA CTD PMID:15885261 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO Benomyl results in increased expression of SERPINE2 mRNA CTD PMID:25530041 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Sh2d4a SH2 domain containing 4A increases expression EXP Benomyl results in increased expression of SH2D4A mRNA CTD PMID:15885261 NCBI chr16:23,084,247...23,156,825
Ensembl chr16:23,083,954...23,156,962
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO Benomyl results in increased expression of TIMP1 mRNA CTD PMID:25530041 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO Benomyl results in increased expression of TIMP2 mRNA CTD PMID:25530041 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tslp thymic stromal lymphopoietin increases expression
multiple interactions
ISO Benomyl results in increased expression of TSLP mRNA
ORMDL3 protein affects the reaction [Benomyl results in increased expression of TSLP mRNA]
CTD PMID:27784618 NCBI chr18:25,613,601...25,618,066
Ensembl chr18:25,613,831...25,617,361
JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO Benomyl results in increased activity of and results in increased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:1,723,135...1,745,147
Ensembl chr  X:1,723,174...1,741,701
JBrowse link
G Vasp vasodilator-stimulated phosphoprotein multiple interactions EXP Benomyl inhibits the reaction [Nitroglycerin results in increased phosphorylation of VASP protein]; Benomyl inhibits the reaction [Pentaerythritol Tetranitrate results in increased phosphorylation of VASP protein] CTD PMID:15331769 NCBI chr 1:80,170,608...80,185,882
Ensembl chr 1:80,170,619...80,185,882
JBrowse link
bithionol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Bithionol inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
G Thra thyroid hormone receptor alpha increases activity EXP Bithionol results in increased activity of THRA protein CTD PMID:22015988 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thrb thyroid hormone receptor beta increases activity EXP Bithionol results in increased activity of THRB protein CTD PMID:22015988 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
carbendazim term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abi2 abl-interactor 2 increases expression EXP carbendazim results in increased expression of ABI2 mRNA CTD PMID:22952946 NCBI chr 9:67,234,612...67,284,504
Ensembl chr 9:67,234,303...67,282,600
JBrowse link
G Acaca acetyl-CoA carboxylase alpha increases expression ISO carbendazim results in increased expression of ACACA mRNA CTD PMID:26071454 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Ache acetylcholinesterase multiple interactions EXP [carbendazim co-treated with mancozeb] results in increased activity of ACHE protein CTD PMID:33217513 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Agpat2 1-acylglycerol-3-phosphate O-acyltransferase 2 increases expression ISO carbendazim results in increased expression of AGPAT2 mRNA CTD PMID:26071454 NCBI chr 3:4,044,741...4,055,384
Ensembl chr 3:4,044,542...4,055,806
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions
affects localization
ISO AHR protein affects the reaction [carbendazim results in increased expression of CYP1A1 protein]
carbendazim affects the localization of AHR protein
CTD PMID:27286660 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Anxa10 annexin A10 increases expression ISO carbendazim results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465
JBrowse link
G Arg1 arginase 1 decreases expression ISO carbendazim results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Bag1 BAG cochaperone 1 increases expression EXP carbendazim results in increased expression of BAG1 mRNA CTD PMID:22952946 NCBI chr 5:57,254,421...57,267,002
Ensembl chr 5:57,254,421...57,267,002
JBrowse link
G Bcl2l14 BCL2 like 14 increases expression EXP carbendazim results in increased expression of BCL2L14 mRNA CTD PMID:22952946 NCBI chr 4:168,139,964...168,183,726
Ensembl chr 4:168,142,271...168,183,096
JBrowse link
G Casp3 caspase 3 increases activity ISO carbendazim results in increased activity of CASP3 protein CTD PMID:30851412 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Clca2 chloride channel accessory 2 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of CLCA2 mRNA CTD PMID:22382377 NCBI chr 2:250,954,423...250,981,544
Ensembl chr 2:250,954,397...250,981,623
JBrowse link
G Cldn11 claudin 11 multiple interactions EXP [carbendazim co-treated with iprodione] results in decreased expression of CLDN11 protein CTD PMID:28576679 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Clu clusterin decreases expression
increases expression
EXP carbendazim results in decreased expression of CLU mRNA
carbendazim results in increased expression of CLU mRNA
CTD PMID:22952946 PMID:27466211 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases activity
increases expression
ISO carbendazim results in increased activity of CYP19A1 protein
carbendazim results in increased expression of CYP19A1 mRNA
CTD PMID:14691014 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression
multiple interactions
ISO
EXP
carbendazim results in increased expression of CYP1A1 mRNA; carbendazim results in increased expression of CYP1A1 protein
2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [carbendazim results in increased expression of CYP1A1 protein]; AHR protein affects the reaction [carbendazim results in increased expression of CYP1A1 protein]; salicylamide inhibits the reaction [carbendazim results in increased expression of CYP1A1 protein]
CTD PMID:10103034 PMID:21784029 PMID:27286660 PMID:32194361 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO carbendazim results in increased expression of CYP1A2 mRNA; carbendazim results in increased expression of CYP1A2 protein CTD PMID:21784029 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 increases expression ISO carbendazim results in increased expression of CYP2B6 mRNA CTD PMID:22310298 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO carbendazim results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO carbendazim results in decreased activity of CYP2D6 protein CTD PMID:20183062 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 increases expression ISO carbendazim results in increased expression of CYP3A4 mRNA CTD PMID:22310298 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO carbendazim results in decreased expression of CYP7A1 mRNA; carbendazim results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Dgat1 diacylglycerol O-acyltransferase 1 increases expression ISO carbendazim results in increased expression of DGAT1 mRNA CTD PMID:26071454 NCBI chr 7:117,566,363...117,576,735
Ensembl chr 7:117,566,368...117,576,737
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 increases expression ISO carbendazim results in increased expression of DGAT2 mRNA CTD PMID:26071454 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Dnaaf11 dynein axonemal assembly factor 11 decreases expression EXP carbendazim results in decreased expression of DNAAF11 mRNA CTD PMID:27466211 NCBI chr 7:107,130,402...107,231,507
Ensembl chr 7:107,130,402...107,223,047
JBrowse link
G Dpp7 dipeptidylpeptidase 7 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of DPP7 mRNA CTD PMID:22382377 NCBI chr 3:2,569,135...2,573,387
Ensembl chr 3:2,569,135...2,573,387
JBrowse link
G Esr1 estrogen receptor 1 decreases expression EXP carbendazim results in decreased expression of ESR1 mRNA CTD PMID:28576679 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 decreases expression EXP carbendazim results in decreased expression of ESR2 mRNA CTD PMID:28576679 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Fank1 fibronectin type III and ankyrin repeat domains 1 increases expression EXP carbendazim results in increased expression of FANK1 mRNA CTD PMID:22952946 NCBI chr 1:205,842,469...205,954,152
Ensembl chr 1:205,842,489...205,950,371
JBrowse link
G Foxa2 forkhead box A2 increases expression ISO carbendazim results in increased expression of FOXA2 mRNA CTD PMID:26071454 NCBI chr 3:142,383,084...142,387,493
Ensembl chr 3:142,383,278...142,387,481
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO carbendazim results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions EXP [carbendazim co-treated with iprodione] results in decreased expression of GJA1 protein CTD PMID:28576679 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Ift81 intraflagellar transport 81 decreases expression EXP carbendazim results in decreased expression of IFT81 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr12:39,420,161...39,507,412
Ensembl chr12:39,423,596...39,506,890
JBrowse link
G Il1b interleukin 1 beta increases expression ISO carbendazim results in increased expression of IL1B mRNA; carbendazim results in increased expression of IL1B protein CTD PMID:26071454 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 increases expression ISO carbendazim results in increased expression of IL6 mRNA; carbendazim results in increased expression of IL6 protein CTD PMID:26071454 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itga5 integrin subunit alpha 5 decreases expression ISO carbendazim results in decreased expression of ITGA5 mRNA CTD PMID:25530041 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO carbendazim results in decreased expression of ITGB1 mRNA CTD PMID:25530041 NCBI chr19:61,677,512...61,725,537
Ensembl chr19:61,677,542...61,725,535
JBrowse link
G Loxl1 lysyl oxidase-like 1 multiple interactions
increases expression
EXP 2,5-hexanedione promotes the reaction [carbendazim results in increased expression of LOXL1 protein]; [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of LOXL1 mRNA CTD PMID:22382377 NCBI chr 8:63,067,757...63,092,124
Ensembl chr 8:63,067,300...63,092,009
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO carbendazim results in decreased expression of LPL protein CTD PMID:30496565 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Macrod1 mono-ADP ribosylhydrolase 1 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] results in decreased expression of MACROD1 mRNA CTD PMID:22382377 NCBI chr 1:222,310,916...222,451,485
Ensembl chr 1:222,310,920...222,451,484
JBrowse link
G Mfap3l microfibril associated protein 3 like increases expression EXP carbendazim results in increased expression of MFAP3L mRNA CTD PMID:22952946 NCBI chr16:32,734,059...32,777,091
Ensembl chr16:32,738,265...32,753,278
JBrowse link
G Mir128-1 microRNA 128-1 increases expression EXP carbendazim results in increased expression of MIR128-1 mRNA CTD PMID:32418910 NCBI chr13:44,916,534...44,916,615
Ensembl chr13:44,916,534...44,916,615
JBrowse link
G Mir423 microRNA 423 increases expression EXP carbendazim results in increased expression of MIR423 mRNA CTD PMID:32418910 NCBI chr10:63,098,366...63,098,444
Ensembl chr10:63,098,360...63,098,453
JBrowse link
G Mmp2 matrix metallopeptidase 2 decreases expression ISO carbendazim results in decreased expression of MMP2 mRNA CTD PMID:25530041 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp9 matrix metallopeptidase 9 decreases expression ISO carbendazim results in decreased expression of MMP9 mRNA CTD PMID:25530041 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases expression ISO carbendazim results in increased expression of NFE2L2 protein CTD PMID:30851412 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO carbendazim inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase increases expression EXP carbendazim results in increased expression of PIM1 mRNA CTD PMID:22952946 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Plau plasminogen activator, urokinase decreases expression ISO carbendazim results in decreased expression of PLAU mRNA CTD PMID:25530041 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Ptgds prostaglandin D2 synthase decreases expression EXP carbendazim results in decreased expression of PTGDS mRNA CTD PMID:22952946 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Serpine2 serpin family E member 2 increases expression ISO carbendazim results in increased expression of SERPINE2 mRNA CTD PMID:25530041 NCBI chr 9:85,560,852...85,629,410
Ensembl chr 9:85,560,863...85,626,094
JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 multiple interactions EXP [carbendazim co-treated with 2,5-hexanedione] affects the expression of SHANK3 mRNA CTD PMID:22382377 NCBI chr 7:130,474,278...130,534,679
Ensembl chr 7:130,474,279...130,534,679
JBrowse link
G Sil1 SIL1 nucleotide exchange factor decreases expression EXP carbendazim results in decreased expression of SIL1 mRNA CTD PMID:22952946 PMID:27466211 NCBI chr18:28,067,476...28,302,008
Ensembl chr18:28,067,484...28,301,863
JBrowse link
G Sod3 superoxide dismutase 3 increases expression EXP carbendazim results in increased expression of SOD3 mRNA CTD PMID:27466211 NCBI chr14:60,958,583...60,971,143
Ensembl chr14:60,958,592...60,964,324
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO carbendazim results in increased expression of SREBF1 mRNA CTD PMID:26071454 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Tbc1d5 TBC1 domain family, member 5 decreases expression EXP carbendazim results in decreased expression of TBC1D5 mRNA CTD PMID:27466211 NCBI chr 9:1,144,641...1,747,732
Ensembl chr 9:1,145,700...1,746,397
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO carbendazim results in increased expression of TIMP1 mRNA CTD PMID:25530041 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 increases expression ISO carbendazim results in increased expression of TIMP2 mRNA CTD PMID:25530041 NCBI chr10:107,338,465...107,386,072
Ensembl chr10:107,338,465...107,386,072
JBrowse link
G Tnp1 transition protein 1 increases expression EXP carbendazim results in increased expression of TNP1 mRNA CTD PMID:28576679 NCBI chr 9:80,294,837...80,295,446
Ensembl chr 9:80,294,840...80,295,446
JBrowse link
G Tnp2 transition protein 2 increases expression EXP carbendazim results in increased expression of TNP2 mRNA CTD PMID:28576679 NCBI chr10:4,953,898...4,954,626
Ensembl chr10:4,953,879...4,954,624
JBrowse link
closantel term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases response to substance
multiple interactions
ISO ABCB1A protein results in decreased susceptibility to closantel
closantel results in increased susceptibility to [ABCB1A protein results in increased transport of Xanthenes]
CTD PMID:20513441 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Bcl3 BCL3, transcription coactivator increases expression EXP closantel results in increased expression of BCL3 mRNA CTD PMID:22015988 NCBI chr 1:80,730,758...80,745,273
Ensembl chr 1:80,730,499...80,744,831
JBrowse link
G Slc25a31 solute carrier family 25 member 31 decreases activity ISO closantel results in decreased activity of SLC25A31 protein CTD PMID:26746582 NCBI chr 2:127,538,323...127,554,276
Ensembl chr 2:127,538,659...127,554,307
JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases activity ISO closantel results in decreased activity of SLC25A4 protein CTD PMID:26746582 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc25a5 solute carrier family 25 member 5 decreases activity ISO closantel results in decreased activity of SLC25A5 protein CTD PMID:26746582 NCBI chr  X:123,404,570...123,407,637
Ensembl chr  X:123,404,518...123,407,645
JBrowse link
G Slc25a6 solute carrier family 25 member 6 decreases activity ISO closantel results in decreased activity of SLC25A6 protein CTD PMID:26746582 NCBI chr18:70,959,872...70,961,040
Ensembl chr18:70,959,887...70,960,786
JBrowse link
G Thra thyroid hormone receptor alpha increases activity EXP closantel results in increased activity of THRA protein CTD PMID:22015988 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Thrb thyroid hormone receptor beta increases activity EXP closantel results in increased activity of THRB protein CTD PMID:22015988 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
costunolide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase increases activity EXP costunolide results in increased activity of CAT protein CTD PMID:20709041 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Il10 interleukin 10 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in decreased expression of IL10 protein] CTD PMID:26970604 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of NOS2 protein] CTD PMID:26970604 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO costunolide inhibits the reaction [Ethanol results in decreased expression of PCNA protein] CTD PMID:26970604 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of PTGS2 protein] CTD PMID:26970604 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO costunolide inhibits the reaction [Ethanol results in increased expression of TNF protein] CTD PMID:26970604 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
coumaphos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO Coumaphos metabolite results in decreased activity of ACHE protein; Coumaphos results in decreased activity of ACHE protein CTD PMID:30625376 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Gpat3 glycerol-3-phosphate acyltransferase 3 increases expression ISO Coumaphos results in increased expression of GPAT3 mRNA CTD PMID:26198647 NCBI chr14:10,343,287...10,396,565
Ensembl chr14:10,343,282...10,395,047
JBrowse link
G Lif LIF, interleukin 6 family cytokine increases expression ISO Coumaphos results in increased expression of LIF mRNA CTD PMID:26198647 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G Rara retinoic acid receptor, alpha increases activity ISO Coumaphos results in increased activity of RARA protein CTD PMID:20143881 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Slc7a11 solute carrier family 7 member 11 increases expression ISO Coumaphos results in increased expression of SLC7A11 mRNA CTD PMID:26198647 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
crystal violet term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Gentian Violet inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Gentian Violet results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO Gentian Violet inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] CTD PMID:21599003 NCBI chr 1:48,318,025...48,360,219
Ensembl chr 1:48,317,995...48,360,261
JBrowse link
dichlorvos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity
decreases expression
multiple interactions
decreases response to substance
increases phosphorylation
increases acylation
ISO
EXP
Dichlorvos metabolite results in decreased activity of ACHE protein; Dichlorvos results in decreased activity of ACHE protein
Dichlorvos results in decreased expression of ACHE protein
1,4-bis(4-hydroxyiminomethylpyridinium)butane dibromide inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; 1-(4-hydroxyiminomethylpyridinium)-4-(4-carbamoylpyridinium)butane inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [Dichlorvos co-treated with Monocrotophos] results in increased activity of ACHE protein; [Monocrotophos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [pralidoxime co-treated with Atropine] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; [sodium arsenite co-treated with Dichlorvos co-treated with Monocrotophos] results in decreased activity of ACHE protein; [sodium arsenite co-treated with Dichlorvos] results in decreased activity of ACHE protein; Dichlorvos inhibits the reaction [sodium arsenite results in increased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [[Atropine co-treated with Curcumin] inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]
ACHE protein results in decreased susceptibility to Dichlorvos
Dichlorvos results in increased phosphorylation of ACHE protein
Dichlorvos results in increased acylation of ACHE protein
[bacoside A co-treated with Plant Preparations] inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; Atropine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; coumarin inhibits the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Dichlorvos binds to and results in decreased activity of ACHE protein; Dichlorvos promotes the reaction [malaoxon results in decreased activity of ACHE protein]; Gallamine Triethiodide affects the reaction [Dichlorvos results in increased acylation of ACHE protein]; Gallamine Triethiodide promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; Propidium promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tubocurarine promotes the reaction [Dichlorvos results in increased phosphorylation of ACHE protein]
[Carbaryl co-treated with Dichlorvos] results in decreased activity of ACHE protein; [crotoxyphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Dichlorvos results in increased phosphorylation of ACHE protein] inhibits the reaction [thioflavin T binds to ACHE protein]; [malaoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Malathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Mevinphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Paraoxon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Parathion co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Phosphamidon co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Physostigmine co-treated with Dichlorvos] results in decreased activity of ACHE protein; [Trichlorfon co-treated with Dichlorvos] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Dichlorvos promotes the reaction [Chlorpromazine results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]
CTD PMID:119426 PMID:235931 PMID:473212 PMID:475593 PMID:597376 PMID:1258061 PMID:1494302 PMID:1609424 PMID:1855619 PMID:2086312 PMID:2537085 PMID:3247000 PMID:3945941 PMID:4859365 PMID:6933967 PMID:7150809 PMID:7218377 PMID:7234437 PMID:7713347 PMID:8231460 PMID:8359835 PMID:8579882 PMID:8783813 PMID:9268605 PMID:9515941 PMID:9586870 PMID:10421444 PMID:10975133 PMID:12018594 PMID:14631503 PMID:15033007 PMID:15679473 PMID:15793557 PMID:15979224 PMID:16036766 PMID:16193528 PMID:16598855 PMID:16978018 PMID:17188317 PMID:17722737 PMID:18070496 PMID:18423506 PMID:19100812 PMID:19631781 PMID:20026515 PMID:20396698 PMID:20412842 PMID:21251949 PMID:21349312 PMID:21673941 PMID:21767560 PMID:22209767 PMID:22783142 PMID:23220589 PMID:25082528 PMID:25895260 PMID:26814074 PMID:27899289 PMID:30625376 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization
multiple interactions
EXP Dichlorvos affects the localization of AIFM1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos affects the localization of AIFM1 protein]
CTD PMID:24231740 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akr7a3 aldo-keto reductase family 7 member A3 increases expression EXP Dichlorvos results in increased expression of AKR7A3 mRNA CTD PMID:21813463 NCBI chr 5:157,801,120...157,813,756
Ensembl chr 5:157,801,163...157,813,756
JBrowse link
G Alb albumin affects binding ISO Dichlorvos binds to ALB protein CTD PMID:15525694 PMID:17188226 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 increases expression EXP Dichlorvos results in increased expression of ALDH1A1 mRNA CTD PMID:21813463 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Anxa2 annexin A2 increases expression EXP Dichlorvos results in increased expression of ANXA2 mRNA CTD PMID:21813463 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Apeh acylaminoacyl-peptide hydrolase decreases activity ISO
EXP
Dichlorvos results in decreased activity of APEH protein CTD PMID:15888665 PMID:19379766 NCBI chr 8:116,862,664...116,871,776
Ensembl chr 8:116,862,625...116,872,215
JBrowse link
G App amyloid beta precursor protein increases secretion ISO
EXP
Dichlorvos results in increased secretion of APP protein alternative form
Dichlorvos results in increased secretion of APP protein modified form
CTD PMID:7605915 PMID:8624119 PMID:11526466 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858
JBrowse link
G Ar androgen receptor multiple interactions ISO Dichlorvos promotes the reaction [Metribolone results in increased activity of AR protein] CTD PMID:17219378 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ATM mRNA]
Dichlorvos results in increased expression of ATM mRNA; Dichlorvos results in increased expression of ATM protein
CTD PMID:24369695 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP Dichlorvos results in increased expression of BAX protein CTD PMID:22817663 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bche butyrylcholinesterase multiple interactions
decreases expression
decreases activity
ISO
EXP
[Dichlorvos results in decreased activity of BCHE protein] which results in increased susceptibility to Succinylcholine; Dichlorvos binds to and results in decreased activity of BCHE protein; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]
Dichlorvos results in decreased expression of BCHE protein
diacetylmonoxime inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Magnesium Sulfate promotes the reaction [Dichlorvos results in decreased activity of BCHE protein]
[bacoside A co-treated with Plant Preparations] inhibits the reaction [Dichlorvos results in decreased expression of BCHE protein]; Dichlorvos binds to and results in decreased activity of BCHE protein
CTD PMID:235931 PMID:423703 PMID:1276991 PMID:4631366 PMID:7150809 PMID:12190811 PMID:12828128 PMID:16036766 PMID:16193528 PMID:16598855 PMID:17698511 PMID:19504058 PMID:20229498 PMID:20395308 PMID:21673941 PMID:21767560 PMID:22209767 PMID:27899289 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Btg2 BTG anti-proliferation factor 2 increases expression EXP Dichlorvos results in increased expression of BTG2 mRNA CTD PMID:21813463 NCBI chr13:50,913,185...50,916,944
Ensembl chr13:50,913,180...50,916,982
JBrowse link
G Casp1 caspase 1 increases expression EXP Dichlorvos results in increased expression of CASP1 mRNA CTD PMID:23053939 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 increases activity
increases cleavage
increases expression
decreases expression
multiple interactions
ISO
EXP
Dichlorvos results in increased activity of CASP3 protein
Dichlorvos results in increased cleavage of CASP3 protein
Dichlorvos results in increased expression of CASP3 mRNA
Dichlorvos results in decreased expression of CASP3 mRNA
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]; Dichlorvos results in increased cleavage of and results in increased activity of CASP3 protein; TEMPOL-H inhibits the reaction [Dichlorvos results in increased cleavage of CASP3 protein]
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dichlorvos results in increased activity of CASP3 protein]
CTD PMID:16973328 PMID:17681413 PMID:17850875 PMID:19815060 PMID:21784090 PMID:22817663 PMID:24369695 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
EXP [Vitamin E co-treated with Ascorbic Acid] inhibits the reaction [Dichlorvos results in increased activity of CASP9 protein] CTD PMID:16973328 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cat catalase multiple interactions
increases activity
decreases activity
EXP
ISO
[Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of CAT protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of CAT protein; [Phorate co-treated with acephate co-treated with Dichlorvos co-treated with Dimethoate] results in decreased activity of CAT protein; Acetylcysteine inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; coenzyme Q10 inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]
Dichlorvos results in increased activity of CAT protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]
CTD PMID:1587340 PMID:20302853 PMID:22034174 PMID:22224058 PMID:22751200 PMID:25891459 PMID:26814074 PMID:27180203 PMID:29143438 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cdc25a cell division cycle 25A increases expression
multiple interactions
EXP Dichlorvos results in increased expression of CDC25A mRNA; Dichlorvos results in increased expression of CDC25A protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDC25A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDC25A protein]
CTD PMID:24369695 NCBI chr 8:117,953,223...117,971,552
Ensembl chr 8:117,953,444...117,971,519
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression
multiple interactions
EXP Dichlorvos results in increased expression of CDKN1A mRNA; Dichlorvos results in increased expression of CDKN1A protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CDKN1A protein]
CTD PMID:21813463 PMID:24369695 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Ces2h carboxylesterase 2H increases expression EXP Dichlorvos results in increased expression of CES2 mRNA CTD PMID:21813463 NCBI chr19:37,052,555...37,067,176
Ensembl chr19:37,052,556...37,067,156
JBrowse link
G Chat choline O-acetyltransferase increases activity EXP Dichlorvos results in increased activity of CHAT protein CTD PMID:17722737 NCBI chr16:8,576,858...8,686,131
Ensembl chr16:8,577,840...8,686,131
JBrowse link
G Chek2 checkpoint kinase 2 multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of CHEK2 protein]
Dichlorvos results in increased expression of CHEK2 mRNA; Dichlorvos results in increased expression of CHEK2 protein
CTD PMID:24369695 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chrm1 cholinergic receptor, muscarinic 1 decreases expression EXP Dichlorvos results in decreased expression of CHRM1 protein CTD PMID:19100812 NCBI chr 1:224,869,087...224,885,101
Ensembl chr 1:224,882,439...224,884,205
JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 decreases expression EXP Dichlorvos results in decreased expression of CHRM2 protein CTD PMID:19100812 NCBI chr 4:64,089,028...64,091,090
Ensembl chr 4:64,088,900...64,091,090
JBrowse link
G Chrm3 cholinergic receptor, muscarinic 3 decreases expression EXP Dichlorvos results in decreased expression of CHRM3 protein CTD PMID:19100812 NCBI chr17:63,990,599...64,463,222
Ensembl chr17:63,990,599...63,994,169
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions ISO Dichlorvos inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:15733544 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit multiple interactions ISO Dichlorvos inhibits the reaction [Acetylcholine affects the activity of [CHRNA4 protein binds to CHRNB2 protein]] CTD PMID:15733544 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions
decreases activity
ISO Dichlorvos inhibits the reaction [CP 55244 binds to CNR1 protein]
Dichlorvos results in decreased activity of CNR1 protein
CTD PMID:12243867 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Creb1 cAMP responsive element binding protein 1 decreases phosphorylation EXP Dichlorvos results in decreased phosphorylation of CREB1 protein CTD PMID:19100812 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Cybb cytochrome b-245 beta chain increases expression EXP Dichlorvos results in increased expression of CYBB mRNA; Dichlorvos results in increased expression of CYBB protein CTD PMID:21964614 NCBI chr  X:14,578,330...14,610,049
Ensembl chr  X:14,578,264...14,612,547
JBrowse link
G Cycs cytochrome c, somatic affects localization
multiple interactions
EXP Dichlorvos affects the localization of CYCS protein
10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide inhibits the reaction [Dichlorvos affects the localization of CYCS protein]
CTD PMID:17850875 PMID:21784090 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Dbh dopamine beta-hydroxylase increases activity
multiple interactions
EXP Dichlorvos results in increased activity of DBH protein
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of DBH protein]
CTD PMID:12186780 NCBI chr 3:5,709,236...5,731,895
Ensembl chr 3:5,709,236...5,731,898
JBrowse link
G Dlg2 discs large MAGUK scaffold protein 2 affects response to substance ISO DLG2 gene SNP affects the susceptibility to Dichlorvos CTD PMID:25622337 NCBI chr 1:154,916,274...157,274,077
Ensembl chr 1:156,552,328...157,269,747
JBrowse link
G Drd2 dopamine receptor D2 decreases activity
multiple interactions
EXP Dichlorvos results in decreased activity of DRD2 protein
Nimodipine inhibits the reaction [Dichlorvos results in decreased activity of DRD2 protein]
CTD PMID:12186780 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Esr1 estrogen receptor 1 decreases activity ISO Dichlorvos results in decreased activity of ESR1 protein CTD PMID:22562034 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fas Fas cell surface death receptor decreases expression ISO Dichlorvos results in decreased expression of FAS protein CTD PMID:15369847 NCBI chr 1:252,589,785...252,624,790
Ensembl chr 1:252,589,785...252,624,790
JBrowse link
G Faslg Fas ligand decreases expression ISO Dichlorvos results in decreased expression of FASL protein CTD PMID:15369847 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Gabrd gamma-aminobutyric acid type A receptor subunit delta decreases expression EXP Dichlorvos results in decreased expression of GABRD mRNA CTD PMID:19146868 NCBI chr 5:172,797,478...172,809,374
Ensembl chr 5:172,797,450...172,809,353
JBrowse link
G Gck glucokinase decreases activity
increases expression
EXP Dichlorvos results in decreased activity of GCK protein
Dichlorvos results in increased expression of GCK mRNA
CTD PMID:16153661 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Gsr glutathione-disulfide reductase decreases expression
increases activity
decreases activity
multiple interactions
EXP Dichlorvos results in decreased expression of GSR protein
Dichlorvos results in increased activity of GSR protein
Dichlorvos results in decreased activity of GSR protein
[Hexachlorocyclohexane co-treated with Dichlorvos co-treated with Plant Extracts] results in decreased activity of GSR protein; [Hexachlorocyclohexane co-treated with Dichlorvos] results in decreased activity of GSR protein; Dichlorvos inhibits the reaction [sodium arsenite results in increased activity of GSR protein]; Plant Extracts inhibits the reaction [Dichlorvos results in decreased activity of GSR protein]; sodium arsenite inhibits the reaction [Dichlorvos results in increased activity of GSR protein]
CTD PMID:18539328 PMID:20302853 PMID:22224058 PMID:22751200 PMID:25895260 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gys2 glycogen synthase 2 increases activity EXP Dichlorvos results in increased activity of GYS2 protein CTD PMID:222008 NCBI chr 4:176,638,632...176,679,805
Ensembl chr 4:176,638,629...176,679,815
JBrowse link
G Gzma granzyme A decreases expression ISO Dichlorvos results in decreased expression of GZMA mRNA; Dichlorvos results in decreased expression of GZMA protein CTD PMID:16002202 NCBI chr 2:44,968,846...44,981,436
Ensembl chr 2:44,968,765...44,981,458
JBrowse link
G Gzmb granzyme B decreases expression ISO Dichlorvos results in decreased expression of GZMB protein CTD PMID:18063463 NCBI chr15:35,413,862...35,417,293
Ensembl chr15:35,413,793...35,417,316
JBrowse link
G Gzmk granzyme K decreases expression ISO Dichlorvos results in decreased expression of GZMK protein CTD PMID:18063463 NCBI chr 2:45,069,136...45,077,154
Ensembl chr 2:45,068,967...45,077,219
JBrowse link
G Hdc histidine decarboxylase increases activity EXP Dichlorvos results in increased activity of HDC protein CTD PMID:119426 NCBI chr 3:119,057,524...119,075,599
Ensembl chr 3:119,057,517...119,075,619
JBrowse link
G Hk1 hexokinase 1 decreases activity EXP Dichlorvos results in decreased activity of HK1 protein CTD PMID:10544956 NCBI chr20:31,911,460...31,979,780
Ensembl chr20:31,912,262...31,956,649
JBrowse link
G Hmox1 heme oxygenase 1 decreases expression
multiple interactions
ISO Dichlorvos results in decreased expression of HMOX1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of HMOX1 protein]
CTD PMID:26814074 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ifng interferon gamma decreases expression EXP Dichlorvos results in decreased expression of IFNG protein CTD PMID:19145326 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il1b interleukin 1 beta increases expression
increases secretion
EXP Dichlorvos results in increased expression of IL1B mRNA; Dichlorvos results in increased expression of IL1B protein
Dichlorvos results in increased secretion of IL1B protein
CTD PMID:21964614 PMID:22817663 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 decreases response to substance ISO Dichlorvos results in decreased susceptibility to IL2 protein CTD PMID:8349949 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6 interleukin 6 increases expression EXP Dichlorvos results in increased expression of IL6 mRNA; Dichlorvos results in increased expression of IL6 protein CTD PMID:21964614 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Itgam integrin subunit alpha M increases expression
multiple interactions
EXP Dichlorvos results in increased expression of ITGAM mRNA; Dichlorvos results in increased expression of ITGAM protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of ITGAM protein]
CTD PMID:21964614 PMID:22817663 PMID:24369695 NCBI chr 1:199,495,312...199,545,738
Ensembl chr 1:199,495,298...199,623,960
JBrowse link
G Lcat lecithin cholesterol acyltransferase decreases activity
multiple interactions
ISO Dichlorvos results in decreased activity of LCAT protein
Dichlorvos inhibits the reaction [[LCAT protein results in increased metabolism of Lecithins] which results in increased chemical synthesis of Cholesterol Esters]
CTD PMID:4847537 NCBI chr19:37,913,333...37,916,799
Ensembl chr19:37,913,336...37,916,813
JBrowse link
G Lpl lipoprotein lipase decreases activity EXP Dichlorvos results in decreased activity of LPL protein CTD PMID:3196159 NCBI chr16:22,537,687...22,561,487
Ensembl chr16:22,537,056...22,561,496
JBrowse link
G Maoa monoamine oxidase A decreases activity EXP Dichlorvos results in decreased activity of MAOA protein CTD PMID:12018584 NCBI chr  X:6,554,698...6,620,722
Ensembl chr  X:6,554,698...6,620,722
JBrowse link
G Maob monoamine oxidase B decreases activity EXP Dichlorvos results in decreased activity of MAOB protein CTD PMID:12018584 NCBI chr  X:6,430,694...6,533,520
Ensembl chr  X:6,430,594...6,533,534
JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions
increases phosphorylation
EXP Nimodipine inhibits the reaction [Dichlorvos results in increased phosphorylation of MAP2 protein] CTD PMID:11282359 PMID:16635102 NCBI chr 9:73,204,753...73,462,965
Ensembl chr 9:73,319,710...73,462,972
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression EXP Dichlorvos results in increased expression of MGMT mRNA CTD PMID:21813463 NCBI chr 1:209,237,255...209,464,189
Ensembl chr 1:209,237,233...209,464,190
JBrowse link
G Nceh1 neutral cholesterol ester hydrolase 1 affects expression
decreases activity
EXP
ISO
Dichlorvos affects the expression of NCEH1 protein modified form
Dichlorvos results in decreased activity of NCEH1 protein
CTD PMID:6245657 PMID:16978018 NCBI chr 2:112,868,834...112,932,622
Ensembl chr 2:112,868,707...112,934,953
JBrowse link
G Nefh neurofilament heavy affects expression EXP Dichlorvos affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Nefl neurofilament light decreases expression EXP Dichlorvos results in decreased expression of NEFL mRNA CTD PMID:19146868 NCBI chr15:44,799,378...44,803,251
Ensembl chr15:44,799,334...44,804,574
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 increases activity
decreases expression
multiple interactions
ISO Dichlorvos results in increased activity of NFE2L2 protein
Dichlorvos results in decreased expression of NFE2L2 mRNA; Dichlorvos results in decreased expression of NFE2L2 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 protein]
CTD PMID:20143881 PMID:25891459 PMID:26814074 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
EXP Dichlorvos results in increased expression of NOS2 mRNA; Dichlorvos results in increased expression of NOS2 protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of NOS2 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of NOS2 protein]
CTD PMID:22817663 PMID:24369695 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression
multiple interactions
ISO Dichlorvos results in decreased expression of NQO1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NQO1 protein]
CTD PMID:26814074 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases activity
increases cleavage
multiple interactions
EXP Dichlorvos results in increased activity of PARP1 protein
Dichlorvos results in increased cleavage of PARP1 protein
N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in increased activity of PARP1 protein]
CTD PMID:24231740 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pnpla6 patatin-like phospholipase domain containing 6 decreases activity ISO
EXP
Dichlorvos results in decreased activity of PNPLA6 protein CTD PMID:7713347 PMID:9268605 PMID:9586870 PMID:10776595 PMID:11282359 PMID:11705460 NCBI chr12:2,068,749...2,098,139
Ensembl chr12:2,069,959...2,097,904
JBrowse link
G Pomc proopiomelanocortin multiple interactions
increases secretion
EXP Dichlorvos inhibits the reaction [POMC protein modified form results in increased chemical synthesis of Adrenal Cortex Hormones]
Dichlorvos results in increased secretion of POMC protein modified form
CTD PMID:2993719 PMID:6245657 NCBI chr 6:28,382,937...28,388,771
Ensembl chr 6:28,382,962...28,388,967
JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity
decreases expression
decreases response to substance
EXP
ISO
1-(4-carbamoylpyridinium)-4-(4-hydroxyiminomethylpyridinium)but-2-ene inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; 1-(4-hydroxyiminomethylpyridinium)-3-(carbamoylpyridinium) propane dibromide inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; asoxime chloride inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; Obidoxime Chloride inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]; Trimedoxime inhibits the reaction [Dichlorvos results in decreased activity of PON1 protein]
Dichlorvos results in decreased expression of PON1 mRNA; Dichlorvos results in decreased expression of PON1 protein
PON1 protein inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of ACHE protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of HMOX1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NFE2L2 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of NQO1 protein]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of PON1 mRNA]; PON1 protein inhibits the reaction [Dichlorvos results in decreased expression of PON1 protein]
PON1 protein results in decreased susceptibility to Dichlorvos
CTD PMID:20412842 PMID:25891459 PMID:26814074 PMID:29098328 NCBI chr 4:30,249,749...30,276,297
Ensembl chr 4:30,249,742...30,276,372
JBrowse link
G Prf1 perforin 1 decreases expression ISO Dichlorvos results in decreased expression of PRF1 mRNA; Dichlorvos results in decreased expression of PRF1 protein CTD PMID:16002202 NCBI chr20:30,915,294...30,920,804
Ensembl chr20:30,915,213...30,921,382
JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions
increases expression
EXP TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of PRKDC mRNA]
Dichlorvos results in increased expression of PRKDC mRNA; Dichlorvos results in increased expression of PRKDC protein
CTD PMID:24369695 NCBI chr11:89,293,547...89,510,948
Ensembl chr11:89,293,696...89,510,871
JBrowse link
G Pygb glycogen phosphorylase B increases activity EXP Dichlorvos results in increased activity of PYGB protein CTD PMID:10544956 NCBI chr 3:146,581,063...146,629,504
Ensembl chr 3:146,582,752...146,634,535
JBrowse link
G Pygl glycogen phosphorylase L increases activity EXP Dichlorvos results in increased activity of PYGL protein CTD PMID:222008 NCBI chr 6:92,597,759...92,643,734
Ensembl chr 6:92,597,706...92,643,847
JBrowse link
G Snca synuclein alpha multiple interactions
affects localization
EXP coenzyme Q10 inhibits the reaction [Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]]; Dichlorvos promotes the reaction [SNCA protein binds to SNCA protein]
Dichlorvos affects the localization of SNCA protein
CTD PMID:21073741 PMID:21843543 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases activity
EXP [10-(6'-ubiquinonyl)decyltriphenylphosphonium bromide results in increased expression of SOD2 protein] which results in decreased susceptibility to Dichlorvos; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of SOD2 protein] CTD PMID:17850875 PMID:21784090 PMID:24231740 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression EXP Dichlorvos results in increased expression of TAP1 mRNA CTD PMID:21813463 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tat tyrosine aminotransferase multiple interactions
increases expression
EXP [Atropine co-treated with Obidoxime Chloride co-treated with Diazepam] inhibits the reaction [Dichlorvos results in increased expression of TAT protein] CTD PMID:7761789 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tf transferrin affects binding ISO Dichlorvos binds to TF protein
Dichlorvos binds to TRF protein
CTD PMID:18930948 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Th tyrosine hydroxylase increases activity
multiple interactions
EXP Dichlorvos results in increased activity of TH protein
Nimodipine inhibits the reaction [Dichlorvos results in increased activity of TH protein]
CTD PMID:12186780 NCBI chr 1:216,073,034...216,080,287
Ensembl chr 1:216,073,031...216,080,287
JBrowse link
G Tnf tumor necrosis factor increases expression
increases secretion
EXP Dichlorvos results in increased expression of TNF mRNA; Dichlorvos results in increased expression of TNF protein
Dichlorvos results in increased secretion of TNF protein
CTD PMID:21964614 PMID:22817663 PMID:23053939 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 decreases expression
increases expression
multiple interactions
EXP Dichlorvos results in decreased expression of TP53 mRNA
Dichlorvos results in increased expression of TP53 mRNA; Dichlorvos results in increased expression of TP53 protein
TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 mRNA]; TEMPOL-H inhibits the reaction [Dichlorvos results in increased expression of TP53 protein]
CTD PMID:23053939 PMID:24369695 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tubb5 tubulin, beta 5 class I increases phosphorylation EXP Dichlorvos results in increased phosphorylation of TUBB protein CTD PMID:11282359 PMID:16635102 NCBI chr20:3,422,448...3,426,420
Ensembl chr20:3,422,461...3,426,371
JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 decreases activity EXP Dichlorvos results in decreased activity of UGP2 protein CTD PMID:222008 NCBI chr14:106,208,174...106,249,322
Ensembl chr14:106,208,176...106,248,539
JBrowse link
G Xab2 XPA binding protein 2 affects response to substance ISO XAB2 gene SNP affects the susceptibility to Dichlorvos CTD PMID:22102698 NCBI chr12:2,158,391...2,170,397
Ensembl chr12:2,158,389...2,170,504
JBrowse link
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G A2m alpha-2-macroglobulin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of A2M mRNA CTD PMID:17547211 NCBI chr 4:154,309,426...154,359,138
Ensembl chr 4:154,309,426...154,359,137
Ensembl chr 4:154,309,426...154,359,137
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 affects response to substance
decreases response to substance
increases secretion
multiple interactions
ISO ABCC1 protein affects the susceptibility to Antimony Potassium Tartrate
ABCC1 protein results in decreased susceptibility to Antimony Potassium Tartrate
ABCC1 protein results in increased secretion of Antimony Potassium Tartrate
[MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Antimony Potassium Tartrate; Glutathione affects the reaction [ABCC1 protein results in increased secretion of Antimony Potassium Tartrate]; verlukast inhibits the reaction [ABCC1 protein results in decreased susceptibility to Antimony Potassium Tartrate]; verlukast inhibits the reaction [ABCC1 protein results in increased secretion of Antimony Potassium Tartrate]
CTD PMID:10025956 PMID:10348353 PMID:11278867 PMID:12018890 PMID:12731862 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression EXP Antimony Potassium Tartrate results in increased expression of ABCC2 mRNA; Antimony Potassium Tartrate results in increased expression of ABCC2 protein CTD PMID:11408547 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Acp2 acid phosphatase 2, lysosomal decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ACP2 mRNA CTD PMID:17547211 NCBI chr 3:80,020,346...80,030,365
Ensembl chr 3:80,021,440...80,030,363
JBrowse link
G Acsl1 acyl-CoA synthetase long-chain family member 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ACSL1 mRNA CTD PMID:17547211 NCBI chr16:48,937,456...49,003,898
Ensembl chr16:48,937,456...49,003,246
JBrowse link
G Adm adrenomedullin increases expression ISO Antimony Potassium Tartrate results in increased expression of ADM mRNA CTD PMID:17547211 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B decreases expression
increases expression
ISO Antimony Potassium Tartrate results in decreased expression of AKR1B1 mRNA
Antimony Potassium Tartrate results in increased expression of AKR1B1 mRNA
CTD PMID:17547211 PMID:28713220 NCBI chr 4:61,706,866...61,720,959
Ensembl chr 4:61,706,864...61,720,956
JBrowse link
G Akr1b10 aldo-keto reductase family 1 member B10 increases expression ISO Antimony Potassium Tartrate results in increased expression of AKR1B10 mRNA CTD PMID:28713220 NCBI chr 4:61,813,265...61,830,371
Ensembl chr 4:61,771,970...61,828,657
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO Antimony Potassium Tartrate results in increased expression of AKR1C2 protein CTD PMID:28713220 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO Antimony Potassium Tartrate results in increased expression of AKR1C3 mRNA; Antimony Potassium Tartrate results in increased expression of AKR1C3 protein CTD PMID:28713220 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Aldh6a1 aldehyde dehydrogenase 6 family, member A1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ALDH6A1 mRNA CTD PMID:17547211 NCBI chr 6:108,146,552...108,167,185
Ensembl chr 6:108,146,582...108,167,185
JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression ISO Antimony Potassium Tartrate results in increased expression of ALDOA mRNA CTD PMID:28713220 NCBI chr 1:198,228,387...198,233,988
Ensembl chr 1:198,228,387...198,233,588
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C increases expression ISO Antimony Potassium Tartrate results in increased expression of ALDOC mRNA CTD PMID:28713220 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Ar androgen receptor increases phosphorylation ISO Antimony Potassium Tartrate results in increased phosphorylation of AR protein CTD PMID:29462692 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ATP2B1 mRNA CTD PMID:17547211 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G Azgp1 alpha-2-glycoprotein 1, zinc-binding decreases expression ISO Antimony Potassium Tartrate results in decreased expression of AZGP1 mRNA CTD PMID:17547211 NCBI chr12:19,196,565...19,203,094
Ensembl chr12:19,196,611...19,202,647
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased expression of BAX protein CTD PMID:32920012 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions EXP
ISO
666-15 compound promotes the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in decreased expression of BCL2 protein]; [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in decreased expression of BCL2 protein CTD PMID:32920012 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bmp6 bone morphogenetic protein 6 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP12 mRNA]; Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP2 mRNA] CTD PMID:28713220 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G Calml5 calmodulin-like 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CALML5 mRNA CTD PMID:28713220 NCBI chr17:70,044,956...70,045,886 JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased cleavage of CASP3 protein CTD PMID:32920012 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Antimony Potassium Tartrate results in increased expression of CCNB2 mRNA CTD PMID:17547211 NCBI chr 8:76,847,972...76,861,165 JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Antimony Potassium Tartrate results in increased expression of CDKN1A mRNA CTD PMID:17547211 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of CDKN3 mRNA CTD PMID:17547211 NCBI chr15:23,553,171...23,564,538
Ensembl chr15:23,553,128...23,564,535
JBrowse link
G Cfb complement factor B decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CFB mRNA CTD PMID:17547211 NCBI chr20:4,536,206...4,542,073
Ensembl chr20:4,536,203...4,561,066
Ensembl chr20:4,536,203...4,561,066
JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of CKS2 mRNA CTD PMID:17547211 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G Clgn calmegin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CLGN mRNA CTD PMID:17547211 NCBI chr19:24,545,257...24,578,527
Ensembl chr19:24,545,318...24,576,798
JBrowse link
G Clptm1 CLPTM1 regulator of GABA type A receptor forward trafficking decreases expression ISO Antimony Potassium Tartrate results in decreased expression of CLPTM1 mRNA CTD PMID:17547211 NCBI chr 1:80,549,051...80,580,665
Ensembl chr 1:80,549,043...80,580,662
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO
EXP
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein
[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein; pyrazolanthrone inhibits the reaction [[Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of CREB1 protein]
CTD PMID:32920012 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Dazap1 DAZ associated protein 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of DAZAP1 mRNA CTD PMID:17547211 NCBI chr 7:12,289,895...12,315,897
Ensembl chr 7:12,290,402...12,311,149
JBrowse link
G Dcp1a decapping mRNA 1A increases expression ISO Antimony Potassium Tartrate results in increased expression of DCP1A mRNA CTD PMID:17547211 NCBI chr16:6,542,415...6,583,856
Ensembl chr16:6,542,216...6,587,619
JBrowse link
G Dsc1 desmocollin 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DSC1 mRNA CTD PMID:28713220 NCBI chr18:11,877,918...11,906,828
Ensembl chr18:11,877,561...11,906,827
JBrowse link
G Dst dystonin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DST protein CTD PMID:28713220 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
JBrowse link
G Duox1 dual oxidase 1 multiple interactions
decreases expression
ISO Antimony Potassium Tartrate inhibits the reaction [IL4 protein results in increased expression of DUOX1 mRNA]
Antimony Potassium Tartrate results in decreased expression of DUOX1 mRNA
CTD PMID:29031483 NCBI chr 3:114,251,794...114,286,827
Ensembl chr 3:114,253,637...114,286,802
JBrowse link
G Duoxa1 dual oxidase maturation factor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of DUOXA1 mRNA CTD PMID:29031483 NCBI chr 3:114,241,057...114,251,720
Ensembl chr 3:114,241,057...114,251,647
JBrowse link
G Dusp1 dual specificity phosphatase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of DUSP1 mRNA CTD PMID:17547211 NCBI chr10:16,970,642...16,973,425
Ensembl chr10:16,970,626...16,973,418
JBrowse link
G Dusp12 dual specificity phosphatase 12 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP12 mRNA] CTD PMID:28713220 NCBI chr13:89,258,309...89,267,402
Ensembl chr13:89,258,310...89,267,402
JBrowse link
G Dusp2 dual specificity phosphatase 2 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [BMP6 protein results in increased expression of DUSP2 mRNA] CTD PMID:28713220 NCBI chr 3:119,776,925...119,779,110
Ensembl chr 3:119,776,925...119,779,099
JBrowse link
G F5 coagulation factor V decreases expression ISO Antimony Potassium Tartrate results in decreased expression of F5 mRNA CTD PMID:17547211 NCBI chr13:82,479,997...82,535,540
Ensembl chr13:82,479,998...82,535,534
JBrowse link
G Fabp5 fatty acid binding protein 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FABP5 mRNA CTD PMID:28713220 NCBI chr 2:93,981,662...93,985,322
Ensembl chr 2:93,981,656...93,985,378
JBrowse link
G Fdft1 farnesyl diphosphate farnesyl transferase 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FDFT1 mRNA CTD PMID:17547211 NCBI chr15:46,339,248...46,367,302
Ensembl chr15:46,339,249...46,367,302
JBrowse link
G Fdps farnesyl diphosphate synthase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FDPS mRNA CTD PMID:17547211 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Flg filaggrin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of FLG mRNA CTD PMID:28713220 NCBI chr 2:193,565,401...193,574,297 JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Antimony Potassium Tartrate results in increased expression of FOSL1 mRNA CTD PMID:17547211 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G Fth1 ferritin heavy chain 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of FTH1 mRNA; Antimony Potassium Tartrate results in increased expression of FTH1 protein CTD PMID:28713220 NCBI chr 1:226,030,940...226,033,228
Ensembl chr 1:226,030,938...226,033,228
JBrowse link
G Ftl1 ferritin light chain 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of FTL mRNA CTD PMID:28713220 NCBI chr 1:101,448,190...101,450,034
Ensembl chr 1:101,448,346...101,449,829
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of G6PD mRNA; Antimony Potassium Tartrate results in increased expression of G6PD protein CTD PMID:28713220 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of GAPDH mRNA CTD PMID:28713220 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO Antimony Potassium Tartrate results in increased expression of GCLC mRNA; Antimony Potassium Tartrate results in increased expression of GCLC protein CTD PMID:28713220 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gclm glutamate cysteine ligase, modifier subunit increases expression ISO Antimony Potassium Tartrate results in increased expression of GCLM mRNA CTD PMID:28713220 NCBI chr 2:225,827,504...225,847,876
Ensembl chr 2:225,827,504...225,847,874
JBrowse link
G Gcnt3 glucosaminyl (N-acetyl) transferase 3, mucin type increases expression ISO Antimony Potassium Tartrate results in increased expression of GCNT3 mRNA CTD PMID:17547211 NCBI chr 8:76,449,078...76,459,431
Ensembl chr 8:76,449,081...76,452,554
JBrowse link
G Ghitm growth hormone inducible transmembrane protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of GHITM mRNA CTD PMID:17547211 NCBI chr16:14,370,269...14,382,647
Ensembl chr16:14,371,531...14,382,641
JBrowse link
G Gla galactosidase, alpha increases expression ISO Antimony Potassium Tartrate results in increased expression of GLA mRNA CTD PMID:17547211 NCBI chr  X:105,405,915...105,417,331
Ensembl chr  X:105,406,792...105,417,323
JBrowse link
G Gtpbp6 GTP binding protein 6 (putative) increases expression ISO Antimony Potassium Tartrate results in increased expression of GTPBP6 mRNA CTD PMID:17547211 NCBI chr12:52,637,000...52,640,869
Ensembl chr12:52,637,000...52,640,839
Ensembl chr12:52,637,000...52,640,839
JBrowse link
G H4c3 H4 clustered histone 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of H4C3 mRNA CTD PMID:17547211 NCBI chr 4:170,144,871...170,145,311
Ensembl chr 4:170,144,951...170,145,262
JBrowse link
G Hmga1 high mobility group AT-hook 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of HMGA1 mRNA CTD PMID:17547211 NCBI chr20:7,132,501...7,140,155
Ensembl chr20:7,136,007...7,138,980
JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of HMOX1 mRNA; Antimony Potassium Tartrate results in increased expression of HMOX1 protein CTD PMID:17547211 PMID:28713220 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of HSD17B2 mRNA CTD PMID:17547211 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of HSD17B7 mRNA CTD PMID:17547211 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Ier2 immediate early response 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of IER2 mRNA CTD PMID:17547211 NCBI chr19:25,774,146...25,775,670
Ensembl chr19:25,774,143...25,775,659
JBrowse link
G Ifrd1 interferon-related developmental regulator 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of IFRD1 mRNA CTD PMID:17547211 NCBI chr 6:60,132,025...60,151,354
Ensembl chr 6:60,132,024...60,151,420
JBrowse link
G Il4 interleukin 4 multiple interactions ISO Antimony Potassium Tartrate inhibits the reaction [IL4 protein results in increased expression of DUOX1 mRNA] CTD PMID:29031483 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Ing3 inhibitor of growth family, member 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of ING3 mRNA CTD PMID:17547211 NCBI chr 4:49,017,235...49,044,450
Ensembl chr 4:49,017,311...49,042,990
JBrowse link
G Itgb3bp integrin subunit beta 3 binding protein increases expression ISO Antimony Potassium Tartrate results in increased expression of ITGB3BP mRNA CTD PMID:17547211 NCBI chr 5:118,476,410...118,541,928
Ensembl chr 5:118,476,430...118,673,780
JBrowse link
G Itih3 inter-alpha trypsin inhibitor, heavy chain 3 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ITIH3 mRNA CTD PMID:17547211 NCBI chr16:6,983,779...7,007,288
Ensembl chr16:6,992,062...7,007,287
JBrowse link
G Ivl involucrin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of IVL mRNA; Antimony Potassium Tartrate results in decreased expression of IVL protein CTD PMID:28713220 NCBI chr 2:192,761,171...192,773,346
Ensembl chr 2:192,761,538...192,763,577
JBrowse link
G Klf6 Kruppel-like factor 6 increases expression ISO Antimony Potassium Tartrate results in increased expression of KLF6 mRNA CTD PMID:17547211 NCBI chr17:67,887,939...67,945,052
Ensembl chr17:67,887,939...67,945,037
JBrowse link
G Krt10 keratin 10 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of KRT10 mRNA; Antimony Potassium Tartrate results in decreased expression of KRT10 protein CTD PMID:28713220 NCBI chr10:87,296,445...87,301,307
Ensembl chr10:87,296,451...87,300,736
JBrowse link
G Krtdap keratinocyte differentiation associated protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of KRTDAP mRNA CTD PMID:28713220 NCBI chr 1:89,234,689...89,235,610
Ensembl chr 1:89,232,439...89,235,598
JBrowse link
G Lipa lipase A, lysosomal acid type decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LIPA mRNA CTD PMID:17547211 NCBI chr 1:252,816,536...252,959,348
Ensembl chr 1:252,816,527...252,849,904
JBrowse link
G Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LRIG1 mRNA CTD PMID:28713220 NCBI chr 4:126,615,998...126,717,434
Ensembl chr 4:126,617,244...126,644,895
JBrowse link
G Lss lanosterol synthase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of LSS mRNA CTD PMID:17547211 NCBI chr20:12,844,522...12,870,474
Ensembl chr20:12,842,884...12,870,497
JBrowse link
G Maff MAF bZIP transcription factor F increases expression ISO Antimony Potassium Tartrate results in increased expression of MAFF mRNA CTD PMID:17547211 NCBI chr 7:120,580,743...120,592,095
Ensembl chr 7:120,580,743...120,592,095
JBrowse link
G Man1a2 mannosidase, alpha, class 1A, member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of MAN1A2 mRNA CTD PMID:17547211 NCBI chr 2:202,891,537...203,043,847
Ensembl chr 2:202,891,537...203,043,847
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of MAPK1 protein CTD PMID:32920012 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP [Antimony Potassium Tartrate results in increased abundance of Antimony] which results in increased phosphorylation of MAPK3 protein CTD PMID:32920012 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of MCM2 mRNA CTD PMID:17547211 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Me1 malic enzyme 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of ME1 mRNA CTD PMID:28713220 NCBI chr 8:94,256,830...94,368,834
Ensembl chr 8:94,256,839...94,368,834
JBrowse link
G Mgat2 alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of MGAT2 mRNA CTD PMID:17547211 NCBI chr 6:91,476,698...91,479,187
Ensembl chr 6:91,476,698...91,479,183
JBrowse link
G Mt2A metallothionein 2A increases expression ISO Antimony Potassium Tartrate results in increased expression of MT2A mRNA CTD PMID:28713220 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance
ISO [MYCN protein affects the expression of ABCC1 mRNA] which affects the susceptibility to Antimony Potassium Tartrate
MYCN protein results in decreased susceptibility to Antimony Potassium Tartrate
CTD PMID:10348353 NCBI chr 6:38,222,554...38,228,419
Ensembl chr 6:38,222,555...38,228,379
JBrowse link
G Ndrg2 NDRG family member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NDRG2 mRNA CTD PMID:17547211 NCBI chr15:28,305,820...28,314,459
Ensembl chr15:28,305,821...28,314,459
JBrowse link
G Nfkbia NFKB inhibitor alpha decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NFKBIA mRNA CTD PMID:17547211 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nkx3-1 NK3 homeobox 1 increases expression
multiple interactions
ISO Antimony Potassium Tartrate results in increased expression of NKX3-1 mRNA; Antimony Potassium Tartrate results in increased expression of NKX3-1 protein
bicalutamide inhibits the reaction [Antimony Potassium Tartrate results in increased expression of NKX3-1 mRNA]
CTD PMID:29462692 NCBI chr15:51,065,316...51,067,908
Ensembl chr15:51,065,316...51,068,421
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of NQO1 mRNA; Antimony Potassium Tartrate results in increased expression of NQO1 protein CTD PMID:28713220 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nqo2 N-ribosyldihydronicotinamide:quinone reductase 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of NQO2 mRNA CTD PMID:28713220 NCBI chr17:32,131,847...32,158,559
Ensembl chr17:32,132,347...32,158,538
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of NR0B2 mRNA CTD PMID:17547211 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Os9 OS9, endoplasmic reticulum lectin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of OS9 mRNA CTD PMID:17547211 NCBI chr 7:70,378,625...70,407,135
Ensembl chr 7:70,380,311...70,407,177
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PDIA4 mRNA CTD PMID:17547211 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pgc progastricsin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PGC mRNA CTD PMID:17547211 NCBI chr 9:15,266,699...15,274,917
Ensembl chr 9:15,266,699...15,274,917
JBrowse link
G Pgd phosphogluconate dehydrogenase increases expression ISO Antimony Potassium Tartrate results in increased expression of PGD protein CTD PMID:28713220 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgm1 phosphoglucomutase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of PGM1 mRNA CTD PMID:28713220 NCBI chr 5:118,743,632...118,803,055
Ensembl chr 5:118,743,632...118,803,055
JBrowse link
G Pgm3 phosphoglucomutase 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of PGM3 mRNA CTD PMID:28713220 NCBI chr 8:94,225,513...94,243,230
Ensembl chr 8:94,225,515...94,243,215
JBrowse link
G Pml PML nuclear body scaffold affects localization
multiple interactions
increases degradation
ISO Antimony Potassium Tartrate affects the localization of PML protein
Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein]
Antimony Potassium Tartrate results in increased degradation of PML protein mutant form
CTD PMID:9834237 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Ppih peptidylprolyl isomerase H increases expression ISO Antimony Potassium Tartrate results in increased expression of PPIH mRNA CTD PMID:17547211 NCBI chr 5:138,343,934...138,361,743
Ensembl chr 5:138,352,916...138,361,702
JBrowse link
G Psph phosphoserine phosphatase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of PSPH mRNA CTD PMID:17547211 NCBI chr12:30,514,128...30,526,551
Ensembl chr12:30,514,112...30,526,557
JBrowse link
G Pttg1 PTTG1 regulator of sister chromatid separation, securin increases expression ISO Antimony Potassium Tartrate results in increased expression of PTTG1 mRNA CTD PMID:17547211 NCBI chr10:29,014,332...29,026,088
Ensembl chr10:29,020,049...29,026,002
JBrowse link
G Rara retinoic acid receptor, alpha increases degradation ISO Antimony Potassium Tartrate results in increased degradation of RARA protein mutant form CTD PMID:9834237 NCBI chr10:86,838,819...86,884,224
Ensembl chr10:86,860,685...86,884,210
JBrowse link
G Rbpms RNA binding protein, mRNA processing factor increases expression ISO Antimony Potassium Tartrate results in increased expression of RBPMS mRNA CTD PMID:17547211 NCBI chr16:61,954,569...62,109,998
Ensembl chr16:61,954,590...62,096,497
JBrowse link
G Rfc2 replication factor C subunit 2 increases expression ISO Antimony Potassium Tartrate results in increased expression of RFC2 mRNA CTD PMID:17547211 NCBI chr12:25,130,375...25,143,480
Ensembl chr12:25,130,377...25,143,480
JBrowse link
G Rnaseh2a ribonuclease H2, subunit A increases expression ISO Antimony Potassium Tartrate results in increased expression of RNASEH2A mRNA CTD PMID:17547211 NCBI chr19:26,074,980...26,084,780
Ensembl chr19:26,074,987...26,084,679
JBrowse link
G Rnh1 ribonuclease/angiogenin inhibitor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RNH1 protein CTD PMID:28713220 NCBI chr 1:214,151,341...214,163,807
Ensembl chr 1:214,151,338...214,163,808
JBrowse link
G Rptn repetin decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RPTN mRNA CTD PMID:28713220 NCBI chr 2:193,722,394...193,729,040
Ensembl chr 2:193,724,248...193,728,302
JBrowse link
G Ryr1 ryanodine receptor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of RYR1 mRNA CTD PMID:28713220 NCBI chr 1:87,959,596...88,066,252
Ensembl chr 1:87,959,712...88,066,101
JBrowse link
G S100a2 S100 calcium binding protein A2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A2 mRNA CTD PMID:28713220 NCBI chr 2:189,981,650...189,985,109 JBrowse link
G S100a8 S100 calcium binding protein A8 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A8 mRNA; Antimony Potassium Tartrate results in decreased expression of S100A8 protein CTD PMID:28713220 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S100a9 S100 calcium binding protein A9 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of S100A9 mRNA; Antimony Potassium Tartrate results in decreased expression of S100A9 protein CTD PMID:28713220 NCBI chr 2:190,097,436...190,100,209
Ensembl chr 2:190,097,554...190,100,276
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SCD mRNA CTD PMID:17547211 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sephs2 selenophosphate synthetase 2 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SEPHS2 mRNA CTD PMID:17547211 NCBI chr 1:198,719,158...198,721,476
Ensembl chr 1:198,719,162...198,721,476
JBrowse link
G Serpinb1a serpin family B member 1A decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SERPINB1 mRNA CTD PMID:17547211 NCBI chr17:32,903,089...32,911,498
Ensembl chr17:32,904,119...32,911,495
JBrowse link
G Serpinc1 serpin family C member 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SERPINC1 mRNA CTD PMID:17547211 NCBI chr13:78,806,107...78,820,375
Ensembl chr13:78,805,347...78,833,192
JBrowse link
G Sik1 salt-inducible kinase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of SIK1 mRNA CTD PMID:17547211 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A increases expression ISO Antimony Potassium Tartrate results in increased expression of SNRPA mRNA CTD PMID:17547211 NCBI chr 1:83,999,670...84,008,429
Ensembl chr 1:83,999,671...84,008,293
JBrowse link
G Sprr1a small proline-rich protein 1A decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR1A mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR1A protein CTD PMID:28713220 NCBI chr 2:192,669,143...192,671,059
Ensembl chr 2:192,669,143...192,671,059
JBrowse link
G Sprr1b small proline-rich protein 1B decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR1B mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR1B protein CTD PMID:28713220 NCBI chr 2:192,622,972...192,624,848
Ensembl chr 2:192,623,244...192,623,681
JBrowse link
G Sprr3 small proline-rich protein 3 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SPRR3 mRNA; Antimony Potassium Tartrate results in decreased expression of SPRR3 protein CTD PMID:28713220 NCBI chr 2:192,641,472...192,643,942
Ensembl chr 2:192,641,790...192,642,548
JBrowse link
G Sqle squalene epoxidase decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SQLE mRNA CTD PMID:17547211 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Srsf1 serine and arginine rich splicing factor 1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SRSF1 mRNA CTD PMID:17547211 NCBI chr10:75,334,200...75,341,197
Ensembl chr10:75,335,146...75,341,197
JBrowse link
G Srsf5 serine and arginine rich splicing factor 5 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of SRSF5 mRNA CTD PMID:17547211 NCBI chr 6:104,611,026...104,640,033
Ensembl chr 6:104,611,026...104,615,302
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of SRXN1 mRNA CTD PMID:28713220 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G St6galnac4 ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of ST6GALNAC4 mRNA CTD PMID:17547211 NCBI chr 3:11,607,103...11,619,595
Ensembl chr 3:11,607,225...11,619,593
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 affects localization
multiple interactions
ISO Antimony Potassium Tartrate affects the localization of SUMO1 protein
Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein]
CTD PMID:9834237 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
G Tardbp TAR DNA binding protein decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TARDBP mRNA CTD PMID:17547211 NCBI chr 5:165,432,089...165,442,232
Ensembl chr 5:165,432,095...165,442,048
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 increases expression ISO Antimony Potassium Tartrate results in increased expression of TNFAIP3 mRNA CTD PMID:17547211 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tnfsf10 TNF superfamily member 10 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TNFSF10 mRNA CTD PMID:17547211 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tob1 transducer of ErbB-2.1 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TOB1 mRNA CTD PMID:17547211 NCBI chr10:81,913,689...81,915,727
Ensembl chr10:81,913,689...81,915,716
JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TPI1 mRNA CTD PMID:28713220 NCBI chr 4:157,328,375...157,331,905
Ensembl chr 4:157,328,379...157,331,905
Ensembl chr 9:157,328,379...157,331,905
JBrowse link
G Tspan7 tetraspanin 7 decreases expression ISO Antimony Potassium Tartrate results in decreased expression of TSPAN7 mRNA CTD PMID:17547211 NCBI chr  X:13,261,551...13,282,886
Ensembl chr  X:13,261,558...13,279,099
JBrowse link
G Tuft1 tuftelin 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TUFT1 mRNA CTD PMID:17547211 NCBI chr 2:195,861,772...195,907,471
Ensembl chr 2:195,861,649...195,908,037
JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO Antimony Potassium Tartrate results in increased expression of TXNRD1 mRNA CTD PMID:17547211 PMID:28713220 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tyms thymidylate synthetase increases expression ISO Antimony Potassium Tartrate results in increased expression of TYMS mRNA CTD PMID:17547211 NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
JBrowse link
G Ube2c ubiquitin-conjugating enzyme E2C increases expression ISO Antimony Potassium Tartrate results in increased expression of UBE2C mRNA CTD PMID:17547211 NCBI chr 3:161,236,971...161,239,371
Ensembl chr 3:161,236,898...161,241,159
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression ISO Antimony Potassium Tartrate results in increased expression of UGT1A6 mRNA CTD PMID:28713220 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Zwint ZW10 interacting kinetochore protein increases expression ISO Antimony Potassium Tartrate results in increased expression of ZWINT mRNA CTD PMID:17547211 NCBI chr20:17,075,781...17,091,715
Ensembl chr20:17,075,771...17,091,766
JBrowse link
dithiazanine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO Dithiazanine results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:7,355,066...7,387,282
Ensembl chr 4:7,355,574...7,387,253
JBrowse link
eprinomectin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases activity ISO eprinomectin results in decreased activity of ABCB1A protein CTD PMID:17134887 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO eprinomectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO eprinomectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
ethoprophos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase decreases activity ISO ethoprop metabolite results in decreased activity of ACHE protein CTD PMID:30625376 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Anxa10 annexin A10 increases expression ISO ethoprophos results in increased expression of ANXA10 mRNA CTD PMID:32194361 NCBI chr16:29,674,699...29,741,521
Ensembl chr16:29,674,793...29,741,465
JBrowse link
G Arg1 arginase 1 decreases expression ISO ethoprophos results in decreased expression of ARG1 mRNA CTD PMID:32194361 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO ethoprophos results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO ethoprophos results in decreased expression of CYP7A1 mRNA; ethoprophos results in decreased expression of CYP7A1 protein CTD PMID:32194361 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO ethoprophos results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:89,286,009...89,296,213
Ensembl chr10:89,285,855...89,296,213
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO ethoprophos binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
fenbendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aurkb aurora kinase B increases expression EXP Fenbendazole results in increased expression of AURKB protein CTD PMID:23411599 NCBI chr10:55,625,860...55,632,399
Ensembl chr10:55,626,741...55,634,991
JBrowse link
G Cbx5 chromobox 5 increases expression EXP Fenbendazole results in increased expression of CBX5 protein CTD PMID:23411599 NCBI chr 7:144,819,673...144,865,014
Ensembl chr 7:144,819,420...144,837,583
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO Fenbendazole results in increased expression of CCL2 protein CTD PMID:20116850 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccnd1 cyclin D1 increases expression EXP Fenbendazole results in increased expression of CCND1 mRNA CTD PMID:23411599 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne2 cyclin E2 increases expression EXP Fenbendazole results in increased expression of CCNE2 mRNA CTD PMID:23411599 NCBI chr 5:24,434,077...24,446,406
Ensembl chr 5:24,434,872...24,446,406
JBrowse link
G Cdk1 cyclin-dependent kinase 1 increases expression EXP Fenbendazole results in increased expression of CDK1 mRNA; Fenbendazole results in increased expression of CDK1 protein CTD PMID:23411599 NCBI chr20:20,576,341...20,591,510
Ensembl chr20:20,576,377...20,591,549
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression EXP Fenbendazole results in increased expression of CDKN1A mRNA; Fenbendazole results in increased expression of CDKN1A protein CTD PMID:23411599 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A increases methylation
increases expression
decreases expression
EXP Fenbendazole results in increased methylation of CDKN2A gene
Fenbendazole results in increased expression of CDKN2A protein
Fenbendazole results in decreased expression of CDKN2A protein
CTD PMID:22659510 PMID:23411599 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP Fenbendazole results in increased expression of CDKN2B mRNA CTD PMID:23411599 NCBI chr 5:107,834,353...107,857,428
Ensembl chr 5:107,845,951...107,858,104
JBrowse link
G Cdr2 cerebellar degeneration-related protein 2 increases expression EXP Fenbendazole results in increased expression of CDR2 mRNA CTD PMID:23411599 NCBI chr 1:190,889,698...190,914,606
Ensembl chr 1:190,889,701...190,914,610
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity ISO Fenbendazole results in decreased activity of CYP1A2 protein CTD PMID:22048645 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO Fenbendazole inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] CTD PMID:23769903 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Il6r interleukin 6 receptor increases expression ISO Fenbendazole results in increased expression of IL6R protein modified form CTD PMID:20116850 NCBI chr 2:189,196,180...189,255,987
Ensembl chr 2:189,205,701...189,254,628
JBrowse link
G Incenp inner centromere protein increases expression EXP Fenbendazole results in increased expression of INCENP protein CTD PMID:23411599 NCBI chr 1:225,923,448...225,953,384
Ensembl chr 1:225,925,773...225,952,516
JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Fenbendazole results in decreased expression of MAPT protein CTD PMID:16930453 NCBI chr10:92,289,002...92,386,517
Ensembl chr10:92,288,910...92,386,517
JBrowse link
G Mdm2 MDM2 proto-oncogene increases expression EXP Fenbendazole results in increased expression of MDM2 mRNA CTD PMID:23411599 NCBI chr 7:60,719,060...60,743,618
Ensembl chr 7:60,719,066...60,743,328
JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression EXP Fenbendazole results in increased expression of MKI67 protein CTD PMID:23411599 NCBI chr 1:207,993,895...208,020,454
Ensembl chr 1:207,993,895...208,020,454
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Fenbendazole inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Tmem70 transmembrane protein 70 multiple interactions EXP [Diethylnitrosamine co-treated with Fenbendazole] results in decreased expression of TMEM70 protein CTD PMID:27914986 NCBI chr 5:2,019,852...2,037,038
Ensembl chr 5:2,019,852...2,037,038
JBrowse link
G Tnf tumor necrosis factor increases secretion
multiple interactions
ISO Fenbendazole results in increased secretion of TNF protein
U 0126 inhibits the reaction [Fenbendazole results in increased secretion of TNF protein]
CTD PMID:20848085 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 increases expression EXP Fenbendazole results in increased expression of TP53 protein CTD PMID:23411599 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Ube2e2 ubiquitin-conjugating enzyme E2E 2 multiple interactions EXP [Diethylnitrosamine co-treated with Fenbendazole] results in decreased expression of UBE2E2 protein CTD PMID:27914986 NCBI chr15:7,402,210...7,928,320
Ensembl chr15:7,871,497...7,927,939
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO Fenbendazole results in increased expression of VEGFA protein CTD PMID:20116850 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Wee1 WEE1 G2 checkpoint kinase decreases expression EXP Fenbendazole results in decreased expression of WEE1 protein modified form CTD PMID:23411599 NCBI chr 1:174,765,228...174,790,882
Ensembl chr 1:174,767,960...174,786,361
JBrowse link
flubendazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arhgef2 Rho/Rac guanine nucleotide exchange factor 2 decreases expression ISO flubendazole results in decreased expression of ARHGEF2 protein CTD PMID:30075109 NCBI chr 2:187,964,100...188,022,847
Ensembl chr 2:187,977,008...188,021,377
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases phosphorylation ISO flubendazole results in increased phosphorylation of BCL2 protein CTD PMID:32652169 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2l1 Bcl2-like 1 increases phosphorylation ISO flubendazole results in increased phosphorylation of BCL2L1 protein CTD PMID:32652169 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO flubendazole results in increased cleavage of CASP3 protein
BAY 11-7085 affects the reaction [flubendazole results in increased cleavage of CASP3 protein]; benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [flubendazole results in increased cleavage of CASP3 protein]; benzoylcarbonyl-valyl-aspartyl-valyl-alanyl-aspartyl-fluoromethyl ketone inhibits the reaction [flubendazole results in increased cleavage of CASP3 protein]; Cyclosporine inhibits the reaction [flubendazole results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [flubendazole results in increased cleavage of CASP3 protein]
CTD PMID:32652169 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdh1 cadherin 1 multiple interactions ISO flubendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein] CTD PMID:30075109 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 multiple interactions ISO flubendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30075109 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 increases activity ISO flubendazole results in increased activity of MAPK8 protein CTD PMID:32652169 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases phosphorylation ISO flubendazole results in increased phosphorylation of MCL1 protein CTD PMID:32652169 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO flubendazole results in increased expression of PMAIP1 protein CTD PMID:32652169 NCBI chr18:62,159,128...62,179,635
Ensembl chr18:62,174,670...62,181,102
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression ISO flubendazole results in decreased expression of PTK2 protein CTD PMID:30075109 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rac1 Rac family small GTPase 1 decreases expression ISO flubendazole results in decreased expression of RAC1 protein CTD PMID:30075109 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases activity
multiple interactions
ISO flubendazole results in increased activity of RELA protein
4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine affects the reaction [flubendazole results in increased activity of RELA protein]; BAY 11-7085 affects the reaction [flubendazole results in increased activity of RELA protein]
CTD PMID:32652169 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Rhoa ras homolog family member A decreases expression ISO flubendazole results in decreased expression of RHOA protein CTD PMID:30075109 NCBI chr 8:117,082,440...117,116,244
Ensembl chr 8:117,106,576...117,116,167
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO flubendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH1 protein]; flubendazole inhibits the reaction [TGFB1 protein results in increased expression of CDH2 protein] CTD PMID:30075109 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tp53 tumor protein p53 increases activity ISO flubendazole results in increased activity of TP53 protein CTD PMID:32652169 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
hycanthone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 increases activity ISO Hycanthone results in increased activity of NR1I2 protein CTD PMID:25455453 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
ivermectin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A affects abundance
increases transport
increases expression
decreases activity
increases export
decreases response to substance
multiple interactions
increases response to substance
affects binding
affects response to substance
ISO ABCB1 gene polymorphism affects the abundance of Ivermectin
ABCB1 protein results in increased transport of Ivermectin
Ivermectin results in increased expression of ABCB1A mRNA
Ivermectin results in decreased activity of ABCB1A protein
ABCB1A protein results in increased export of Ivermectin
ABCB1A protein results in decreased susceptibility to Ivermectin
[ABCB1A protein co-treated with ABCB1B protein] affects the susceptibility to Ivermectin; Ivermectin inhibits the reaction [ABCB1A protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; Ivermectin results in increased expression of and results in increased stability of ABCB1A mRNA; Ivermectin results in increased susceptibility to [ABCB1A protein results in increased transport of Xanthenes]
ABCB1A gene mutant form results in increased susceptibility to Ivermectin; ABCB1A protein mutant form results in increased susceptibility to Ivermectin
Ivermectin results in decreased activity of ABCB1 protein
ABCB1 protein affects the abundance of Ivermectin
Ivermectin inhibits the reaction [ABCB1 protein results in increased export of Doxorubicin]; Ivermectin inhibits the reaction [ABCB1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]; spinosad inhibits the reaction [ABCB1 protein results in increased transport of Ivermectin]
Ivermectin binds to ABCB1 protein
ABCB1 gene polymorphism affects the susceptibility to Ivermectin
CTD PMID:8917702 PMID:8949985 PMID:9144452 PMID:17134887 PMID:18633165 PMID:19161460 PMID:20513441 PMID:20595473 PMID:20630055 PMID:21321059 PMID:22024132 PMID:22834856 PMID:24998875 PMID:25865432 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B multiple interactions
increases expression
ISO [ABCB1A protein co-treated with ABCB1B protein] affects the susceptibility to Ivermectin; Ivermectin results in increased expression of and results in increased stability of ABCB1B mRNA
Ivermectin results in increased expression of ABCB1B mRNA
CTD PMID:19161460 PMID:22024132 PMID:24998875 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions
decreases activity
ISO Ivermectin inhibits the reaction [ABCC1 protein results in increased transport of bisbenzimide ethoxide trihydrochloride]
Ivermectin results in decreased activity of ABCC1 protein
CTD PMID:25865432 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression ISO Ivermectin results in increased expression of ABCC2 mRNA CTD PMID:24998875 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Ivermectin results in increased expression of ABCG2 mRNA CTD PMID:24998875 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Acaca acetyl-CoA carboxylase alpha affects expression
decreases expression
multiple interactions
ISO Ivermectin affects the expression of ACACA mRNA
Ivermectin results in decreased expression of ACACA mRNA
Ivermectin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of ACACA protein]
Ivermectin inhibits the reaction [Palmitic Acid results in decreased phosphorylation of ACACA protein]
CTD PMID:30738135 PMID:31199990 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Adcy7 adenylate cyclase 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ADCY7 mRNA CTD PMID:16861626 NCBI chr19:19,702,307...19,762,973
Ensembl chr19:19,704,859...19,727,081
JBrowse link
G Adm adrenomedullin decreases expression ISO Ivermectin results in decreased expression of ADM mRNA CTD PMID:28942281 NCBI chr 1:175,443,189...175,447,260
Ensembl chr 1:175,445,088...175,447,259
JBrowse link
G Aldh1l2 aldehyde dehydrogenase 1 family, member L2 increases expression ISO Ivermectin results in increased expression of ALDH1L2 mRNA CTD PMID:28942281 NCBI chr 7:26,375,866...26,425,838
Ensembl chr 7:26,375,866...26,425,108
JBrowse link
G Angptl6 angiopoietin-like 6 increases expression ISO Ivermectin results in increased expression of ANGPTL6 mRNA CTD PMID:28942281 NCBI chr 8:21,895,523...21,902,002
Ensembl chr 8:21,895,524...21,901,829
JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of ARL4C mRNA CTD PMID:16861626 NCBI chr 9:95,783,651...95,787,092
Ensembl chr 9:95,786,508...95,787,094
JBrowse link
G Atf4 activating transcription factor 4 increases expression ISO Ivermectin results in increased expression of ATF4 mRNA CTD PMID:28942281 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf5 activating transcription factor 5 increases expression ISO Ivermectin results in increased expression of ATF5 mRNA CTD PMID:28942281 NCBI chr 1:100,807,821...100,812,410
Ensembl chr 1:100,808,241...100,810,522
JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Ivermectin results in increased expression of ATF6 mRNA CTD PMID:28942281 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of BAG3 mRNA CTD PMID:16861626 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Ivermectin results in increased expression of BAX protein CTD PMID:28811376 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 multiple interactions ISO Ivermectin inhibits the reaction [geranylgeranic acid results in increased expression of BBC3 mRNA] CTD PMID:24658405 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bnip3 BCL2 interacting protein 3 decreases expression ISO Ivermectin results in decreased expression of BNIP3 mRNA CTD PMID:28942281 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Camp cathelicidin antimicrobial peptide decreases expression ISO Ivermectin results in decreased expression of CAMP mRNA; Ivermectin results in decreased expression of CAMP protein CTD PMID:28653460 NCBI chr 8:117,930,557...117,932,371
Ensembl chr 8:117,930,546...117,932,518
JBrowse link
G Cat catalase decreases activity
multiple interactions
EXP Ivermectin results in decreased activity of CAT protein
Thioctic Acid inhibits the reaction [Ivermectin results in decreased activity of CAT protein]
CTD PMID:28880400 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCL3 protein CTD PMID:16861626 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccr7 C-C motif chemokine receptor 7 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CCR7 mRNA CTD PMID:16861626 NCBI chr10:87,057,335...87,067,444
Ensembl chr10:87,057,136...87,067,456
JBrowse link
G Cct3 chaperonin containing TCP1 subunit 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of CCT3 mRNA CTD PMID:16861626 NCBI chr 2:187,669,051...187,693,610
Ensembl chr 2:187,668,796...187,693,610
JBrowse link
G Cd36 CD36 molecule affects expression ISO Ivermectin affects the expression of CD36 mRNA CTD PMID:31199990 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cdh1 cadherin 1 increases expression ISO Ivermectin results in increased expression of CDH1 CTD PMID:26078298 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Ivermectin results in increased expression of CDKN1A protein CTD PMID:28811376 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B increases expression ISO Ivermectin results in increased expression of CDKN1B protein CTD PMID:28811376 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha affects expression
multiple interactions
ISO Ivermectin affects the expression of CEBPA mRNA
Ivermectin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of CEBPA protein]; Rosiglitazone affects the reaction [Ivermectin affects the expression of CEBPA mRNA]
CTD PMID:31199990 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cox6a2 cytochrome c oxidase subunit 6A2 increases expression ISO Ivermectin results in increased expression of COX6A2 mRNA; Ivermectin results in increased expression of COX6A2 protein CTD PMID:28942281 NCBI chr 1:199,624,037...199,626,255
Ensembl chr 1:199,624,037...199,624,783
JBrowse link
G Cpt1a carnitine palmitoyltransferase 1A affects expression
multiple interactions
ISO Ivermectin affects the expression of CPT1A mRNA
Ivermectin inhibits the reaction [Palmitic Acid results in increased expression of CPT1A mRNA]
CTD PMID:30738135 PMID:31199990 NCBI chr 1:218,568,157...218,629,679
Ensembl chr 1:218,569,510...218,629,678
JBrowse link
G Crp C-reactive protein increases expression ISO Ivermectin results in increased expression of CRP protein CTD PMID:8555762 NCBI chr13:91,080,448...91,081,358
Ensembl chr13:91,054,974...91,093,713
JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of CTSL mRNA CTD PMID:16861626 NCBI chr17:1,873,105...1,879,266
Ensembl chr17:1,872,848...1,879,279
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
increases expression
ISO Ivermectin results in decreased activity of CYP1A1 protein
Ivermectin results in increased expression of CYP1A1 mRNA
CTD PMID:18420780 PMID:24998875 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO Ivermectin results in increased expression of CYP1A2 mRNA CTD PMID:24998875 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity ISO Ivermectin results in decreased activity of CYP1B1 protein CTD PMID:18420780 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity
increases expression
ISO Ivermectin results in decreased activity of CYP2B10 protein
Ivermectin results in increased expression of CYP2B10 mRNA
CTD PMID:18420780 PMID:24998875 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2c79 cytochrome P450, family 2, subfamily c, polypeptide 79 decreases activity ISO Ivermectin results in decreased activity of CYP2C29 protein CTD PMID:18420780 NCBI chr 1:147,236,480...147,307,988 JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 decreases activity ISO Ivermectin results in decreased activity of CYP2D6 protein
Ivermectin results in decreased activity of CYP2D22 protein
CTD PMID:11124226 PMID:18420780 NCBI chr 7:123,599,264...123,608,436
Ensembl chr 7:123,599,266...123,608,436
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity ISO Ivermectin results in decreased activity of CYP2E1 protein CTD PMID:18420780 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 decreases activity ISO Ivermectin results in decreased activity of CYP3A4 protein CTD PMID:11124226 PMID:18420780 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
affects expression
multiple interactions
ISO Ivermectin results in increased expression of DDIT3 mRNA
Ivermectin affects the expression of DDIT3 mRNA
Ivermectin promotes the reaction [Palmitic Acid results in increased expression of DDIT3 protein]
CTD PMID:28942281 PMID:30738135 PMID:31199990 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DNAJB1 mRNA CTD PMID:16861626 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of DPYSL2 mRNA CTD PMID:16861626 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 increases expression ISO Ivermectin results in increased expression of EDEM1 mRNA CTD PMID:28942281 NCBI chr 4:140,886,644...140,918,654
Ensembl chr 4:140,886,545...140,915,779
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Egln3 egl-9 family hypoxia-inducible factor 3 decreases expression ISO Ivermectin results in decreased expression of EGLN3 mRNA CTD PMID:28942281 NCBI chr 6:75,050,329...75,075,795
Ensembl chr 6:75,050,329...75,075,795
JBrowse link
G Esr1 estrogen receptor 1 increases expression ISO Ivermectin results in increased expression of ESR1 CTD PMID:26078298 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Fabp4 fatty acid binding protein 4 affects expression
multiple interactions
ISO Ivermectin affects the expression of FABP4 mRNA
Rosiglitazone affects the reaction [Ivermectin affects the expression of FABP4 mRNA]
CTD PMID:31199990 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Fasn fatty acid synthase affects expression ISO Ivermectin affects the expression of FASN mRNA CTD PMID:31199990 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Ivermectin results in increased expression of GDF15 mRNA CTD PMID:28942281 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gem GTP binding protein overexpressed in skeletal muscle multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of GEM mRNA CTD PMID:16861626 NCBI chr 5:25,339,479...25,353,661
Ensembl chr 5:25,349,928...25,353,661
JBrowse link
G Glra1 glycine receptor, alpha 1 increases activity
multiple interactions
affects activity
ISO Ivermectin results in increased activity of GLRA1 protein mutant form
Ivermectin affects the reaction [Glycine affects the activity of GLRA1 protein mutant form]
Ivermectin affects the activity of GLRA1 protein mutant form
CTD PMID:25231486 PMID:27958714 NCBI chr10:40,851,955...40,954,364
Ensembl chr10:40,855,559...40,953,651
JBrowse link
G Glra3 glycine receptor, alpha 3 affects expression ISO Ivermectin affects the expression of GLRA3 mRNA CTD PMID:31199990 NCBI chr16:37,676,959...37,908,221
Ensembl chr16:37,676,962...38,063,821
JBrowse link
G Glrb glycine receptor, beta affects expression ISO Ivermectin affects the expression of GLRB mRNA CTD PMID:31199990 NCBI chr 2:179,768,040...179,842,612
Ensembl chr 2:179,769,009...179,842,547
JBrowse link
G Gpr183 G protein-coupled receptor 183 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of GPR183 mRNA CTD PMID:16861626 NCBI chr15:108,364,701...108,376,221
Ensembl chr15:108,364,701...108,376,221
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AA1 mRNA CTD PMID:16861626 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSP90AB1 mRNA CTD PMID:16861626 NCBI chr 9:17,817,791...17,823,163
Ensembl chr 9:17,817,721...17,823,243
JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression
multiple interactions
EXP Ivermectin results in increased expression of HSPA1A mRNA
Thioctic Acid inhibits the reaction [Ivermectin results in increased expression of HSPA1A mRNA]
CTD PMID:28880400 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA4 mRNA CTD PMID:16861626 NCBI chr10:38,601,624...38,642,397
Ensembl chr10:38,601,624...38,642,397
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Ivermectin results in increased expression of HSPA5 protein CTD PMID:30738135 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPA8 mRNA CTD PMID:16861626 NCBI chr 8:44,989,401...44,993,261
Ensembl chr 8:44,990,014...44,993,179
JBrowse link
G Hspa9 heat shock protein family A (Hsp70) member 9 increases expression ISO Ivermectin results in increased expression of HSPA9 mRNA CTD PMID:28942281 NCBI chr18:27,731,072...27,749,235
Ensembl chr18:27,731,072...27,749,235
JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 multiple interactions
increases expression
ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPD1 mRNA
Ivermectin results in increased expression of HSPD1 mRNA
CTD PMID:16861626 PMID:28942281 NCBI chr 9:61,680,529...61,691,202
Ensembl chr 9:61,680,530...61,690,956
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPE1 mRNA CTD PMID:16861626 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of HSPH1 mRNA CTD PMID:16861626 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression
multiple interactions
EXP Ivermectin results in increased expression of IGFBP3 mRNA
Thioctic Acid inhibits the reaction [Ivermectin results in increased expression of IGFBP3 mRNA]
CTD PMID:28880400 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL10 protein CTD PMID:16861626 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1a interleukin 1 alpha multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1A protein CTD PMID:16861626 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1r1 interleukin 1 receptor type 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of IL1R1 mRNA CTD PMID:16861626 NCBI chr 9:46,962,291...47,038,139
Ensembl chr 9:46,962,288...47,036,670
JBrowse link
G Lonp1 lon peptidase 1, mitochondrial increases expression ISO Ivermectin results in increased expression of LONP1 mRNA CTD PMID:28942281 NCBI chr 9:10,428,853...10,441,180
Ensembl chr 9:10,428,853...10,441,177
JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of MAP3K8 mRNA CTD PMID:16861626 NCBI chr17:56,109,403...56,129,925
Ensembl chr17:56,109,549...56,129,919
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK1 protein] CTD PMID:19168156 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK3 protein] CTD PMID:19168156 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased phosphorylation of MAPK8 protein] CTD PMID:19168156 NCBI chr16:9,620,854...9,709,342
Ensembl chr16:9,625,177...9,709,347
JBrowse link
G Mxd1 max dimerization protein 1 multiple interactions ISO Ivermectin inhibits the reaction [MXD1 protein binds to SIN3A protein] CTD PMID:26078298 NCBI chr 4:118,451,752...118,472,150
Ensembl chr 4:118,449,882...118,472,179
JBrowse link
G Myh4 myosin heavy chain 4 multiple interactions EXP Ivermectin inhibits the reaction [Potassium Chloride affects the localization of MYH4 protein] CTD PMID:29293066 NCBI chr10:53,778,456...53,801,605
Ensembl chr10:53,713,938...53,848,347
JBrowse link
G Nanog Nanog homeobox decreases expression ISO Ivermectin results in decreased expression of NANOG mRNA; Ivermectin results in decreased expression of NANOG protein CTD PMID:29257278 NCBI chr 4:155,531,906...155,539,268
Ensembl chr 4:155,531,906...155,539,268
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO Ivermectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]] CTD PMID:27773686 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Ndrg1 N-myc downstream regulated 1 decreases expression ISO Ivermectin results in decreased expression of NDRG1 mRNA CTD PMID:28942281 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein] CTD PMID:19168156 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nppb natriuretic peptide B multiple interactions ISO Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB mRNA]; Ivermectin inhibits the reaction [EDN1 protein results in increased expression of NPPB protein] CTD PMID:28942281 NCBI chr 5:164,796,176...164,797,538
Ensembl chr 5:164,796,185...164,797,531
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases expression ISO Ivermectin results in decreased expression of NQO1 mRNA; Ivermectin results in decreased expression of NQO1 protein CTD PMID:22021338 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions
increases expression
affects expression
ISO Ivermectin inhibits the reaction [Chenodeoxycholic Acid promotes the reaction [NCOA2 protein modified form binds to NR1H4 protein]]
Ivermectin results in increased expression of NR1H4 mRNA
Ivermectin affects the expression of NR1H4 mRNA
CTD PMID:27773686 PMID:30738135 PMID:31199990 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator increases expression ISO Ivermectin results in increased expression of NUPR1 mRNA CTD PMID:28942281 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G P2rx4 purinergic receptor P2X 4 multiple interactions
increases activity
ISO Ivermectin promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX4 protein]
Ivermectin results in increased activity of P2RX4 protein
CTD PMID:19560503 PMID:21638035 PMID:30545933 NCBI chr12:39,308,022...39,325,673
Ensembl chr12:39,308,025...39,325,673
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression ISO Ivermectin results in increased expression of PARP1 protein modified form CTD PMID:28811376 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pfkl phosphofructokinase, liver type decreases expression ISO Ivermectin results in decreased expression of PFKL mRNA CTD PMID:28942281 NCBI chr20:11,393,860...11,415,889
Ensembl chr20:11,393,877...11,415,882
JBrowse link
G Pou5f1 POU class 5 homeobox 1 decreases expression ISO Ivermectin results in decreased expression of POU5F1 mRNA; Ivermectin results in decreased expression of POU5F1 protein CTD PMID:29257278 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression
multiple interactions
ISO Ivermectin results in decreased expression of PPARA mRNA
Ivermectin inhibits the reaction [Palmitic Acid results in increased expression of PPARA mRNA]
CTD PMID:30738135 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects expression
multiple interactions
ISO Ivermectin affects the expression of PPARG mRNA
Ivermectin inhibits the reaction [[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS1 protein] results in increased expression of PPARG protein]; Rosiglitazone affects the reaction [Ivermectin affects the expression of PPARG mRNA]
CTD PMID:31199990 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppid peptidylprolyl isomerase D multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPID mRNA CTD PMID:16861626 NCBI chr 2:178,354,830...178,366,843
Ensembl chr 2:178,354,890...178,366,685
JBrowse link
G Ppif peptidylprolyl isomerase F multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of PPIF mRNA CTD PMID:16861626 NCBI chr16:1,979,191...1,985,912
Ensembl chr16:1,979,191...1,985,908
JBrowse link
G Ptges3 prostaglandin E synthase 3 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of PTGES3 mRNA CTD PMID:16861626 NCBI chr 7:2,479,267...2,497,024
Ensembl chr 7:2,479,311...2,497,013
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 mRNA]; Ivermectin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein] CTD PMID:19168156 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Rpp14 ribonuclease P/MRP subunit p14 increases expression ISO Ivermectin results in increased expression of RPP14 mRNA CTD PMID:28942281 NCBI chr15:18,625,963...18,636,157
Ensembl chr15:18,625,964...18,632,536
JBrowse link
G Serpine1 serpin family E member 1 decreases expression ISO Ivermectin results in decreased expression of SERPINE1 mRNA CTD PMID:28942281 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Sin3a SIN3 transcription regulator family member A multiple interactions ISO Ivermectin inhibits the reaction [MXD1 protein binds to SIN3A protein] CTD PMID:26078298 NCBI chr 8:61,748,590...61,803,314
Ensembl chr 8:61,762,768...61,803,099
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of SKAP2 mRNA CTD PMID:16861626 NCBI chr 4:81,816,778...81,968,832
Ensembl chr 4:81,818,569...81,968,832
JBrowse link
G Slc2a1 solute carrier family 2 member 1 decreases expression ISO Ivermectin results in decreased expression of SLC2A1 mRNA CTD PMID:28942281 NCBI chr 5:138,154,677...138,182,897
Ensembl chr 5:138,154,673...138,182,897
JBrowse link
G Slc2a4 solute carrier family 2 member 4 affects expression ISO Ivermectin affects the expression of SLC2A4 mRNA CTD PMID:31199990 NCBI chr10:56,552,921...56,558,562
Ensembl chr10:56,552,983...56,558,487
JBrowse link
G Sox2 SRY-box transcription factor 2 decreases expression ISO Ivermectin results in decreased expression of SOX2 mRNA; Ivermectin results in decreased expression of SOX2 protein CTD PMID:29257278 NCBI chr 2:121,165,137...121,167,545
Ensembl chr 2:121,165,137...121,167,545
JBrowse link
G Sphk1 sphingosine kinase 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of SPHK1 mRNA CTD PMID:16861626 NCBI chr10:105,498,728...105,504,401
Ensembl chr10:105,498,728...105,504,393
JBrowse link
G St13 ST13, Hsp70 interacting protein multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of ST13 mRNA CTD PMID:16861626 NCBI chr 7:122,585,770...122,635,731
Ensembl chr 7:122,585,771...122,635,731
JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in increased expression of TCP1 mRNA CTD PMID:16861626 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Tfrc transferrin receptor decreases expression ISO Ivermectin results in decreased expression of TFRC mRNA CTD PMID:28942281 NCBI chr11:71,397,423...71,419,263
Ensembl chr11:71,397,383...71,419,223
JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TGIF1 mRNA CTD PMID:16861626 NCBI chr 9:119,181,079...119,190,698
Ensembl chr 9:119,181,083...119,190,698
JBrowse link
G Tlr2 toll-like receptor 2 decreases expression ISO Ivermectin results in decreased expression of TLR2 protein CTD PMID:28653460 NCBI chr 2:182,840,171...182,846,061
Ensembl chr 2:182,840,727...182,846,061
JBrowse link
G Tlr4 toll-like receptor 4 decreases expression ISO Ivermectin results in decreased expression of TLR4 mRNA CTD PMID:28653460 NCBI chr 5:82,587,424...82,601,056
Ensembl chr 5:82,587,420...82,601,052
JBrowse link
G Tnf tumor necrosis factor decreases expression ISO Ivermectin results in decreased expression of TNF mRNA CTD PMID:28653460 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO Ivermectin inhibits the reaction [geranylgeranic acid affects the localization of TP53 protein mutant form] CTD PMID:24658405 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Trib3 tribbles pseudokinase 3 increases expression ISO Ivermectin results in increased expression of TRIB3 mRNA CTD PMID:28942281 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 multiple interactions ISO [Ivermectin co-treated with Albendazole] results in decreased expression of TSC22D1 mRNA CTD PMID:16861626 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
kainic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP Kainic Acid results in increased expression of ABCB1A mRNA; Kainic Acid results in increased expression of ABCB1A protein CTD PMID:14706787 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP Kainic Acid results in increased expression of ABCB1B mRNA; Kainic Acid results in increased expression of ABCB1B protein CTD PMID:14706787 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 increases expression ISO Kainic Acid results in increased expression of ABCG2 mRNA CTD PMID:17997037 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Aco2 aconitase 2 multiple interactions
decreases activity
EXP 6-Cyano-7-nitroquinoxaline-2,3-dione inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [Kainic Acid results in decreased activity of ACO2 protein] CTD PMID:11520895 NCBI chr 7:123,102,493...123,145,608
Ensembl chr 7:123,102,468...123,145,635
JBrowse link
G Acp1 acid phosphatase 1 decreases expression ISO Kainic Acid results in decreased expression of ACP1 mRNA CTD PMID:17997037 NCBI chr 6:49,836,064...49,851,714
Ensembl chr 6:49,836,075...49,851,714
JBrowse link
G Adk adenosine kinase increases expression ISO Kainic Acid results in increased expression of ADK mRNA CTD PMID:17997037 NCBI chr15:3,033,535...3,435,888
Ensembl chr15:3,033,495...3,435,888
JBrowse link
G Adnp activity-dependent neuroprotector homeobox multiple interactions
decreases expression
EXP Enzyme Inhibitors inhibits the reaction [Kainic Acid results in decreased expression of ADNP protein]
Kainic Acid results in decreased expression of ADNP mRNA; Kainic Acid results in decreased expression of ADNP protein
CTD PMID:18375135 NCBI chr 3:164,937,188...164,964,819
Ensembl chr 3:164,937,198...164,964,702
JBrowse link
G Adra1b adrenoceptor alpha 1B increases response to substance ISO ADRA1B protein results in increased susceptibility to Kainic Acid CTD PMID:19125850 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression
multiple interactions
EXP Kainic Acid results in increased expression of AIF1 protein
NADP inhibits the reaction [Kainic Acid results in increased expression of AIF1 protein]
CTD PMID:32057834 NCBI chr20:5,161,350...5,167,176
Ensembl chr20:5,161,333...5,166,448
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 increases localization
multiple interactions
ISO Kainic Acid results in increased localization of AIFM1 protein
Minocycline inhibits the reaction [Kainic Acid results in increased localization of AIFM1 protein]
CTD PMID:16469440 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Alox5ap arachidonate 5-lipoxygenase activating protein increases expression EXP Kainic Acid results in increased expression of ALOX5AP mRNA CTD PMID:19700661 NCBI chr12:6,854,930...6,879,112
Ensembl chr12:6,854,920...6,879,154
JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO Kainic Acid results in increased expression of APAF1 mRNA CTD PMID:17997037 NCBI chr 7:31,699,309...31,784,192
Ensembl chr 7:31,699,885...31,784,192
JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 multiple interactions EXP [Raloxifene Hydrochloride co-treated with Kainic Acid] results in increased expression of APEX1 mRNA CTD PMID:16120186 NCBI chr15:27,849,943...27,852,083
Ensembl chr15:27,849,979...27,852,082
JBrowse link
G Apoe apolipoprotein E decreases expression ISO Kainic Acid results in decreased expression of APOE mRNA CTD PMID:17997037 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Arc activity-regulated cytoskeleton-associated protein increases expression EXP
ISO
Kainic Acid results in increased expression of ARC mRNA; Kainic Acid results in increased expression of ARC protein CTD PMID:17632064 PMID:30557575 NCBI chr 7:115,907,097...115,911,059
Ensembl chr 7:115,907,097...115,910,541
JBrowse link
G Atf7ip activating transcription factor 7 interacting protein decreases expression EXP Kainic Acid results in decreased expression of ATF7IP mRNA CTD PMID:19700661 NCBI chr 4:170,476,998...170,563,063
Ensembl chr 4:170,518,673...170,559,532
JBrowse link
G Atg5 autophagy related 5 multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of ATG5 protein] CTD PMID:32057834 NCBI chr20:49,301,783...49,393,147
Ensembl chr20:49,318,308...49,393,140
JBrowse link
G B4galt2 beta-1,4-galactosyltransferase 2 decreases expression ISO Kainic Acid results in decreased expression of B4GALT2 mRNA CTD PMID:17997037 NCBI chr 5:136,707,510...136,717,345
Ensembl chr 5:136,707,510...136,715,981
JBrowse link
G Bag3 BAG cochaperone 3 increases expression EXP Kainic Acid results in increased expression of BAG3 mRNA CTD PMID:19700661 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
EXP
ISO
Kainic Acid results in increased expression of BAX mRNA; Kainic Acid results in increased expression of BAX protein
oridonin inhibits the reaction [Kainic Acid results in increased expression of BAX mRNA]
EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]]
Valproic Acid inhibits the reaction [Kainic Acid results in increased expression of BAX protein]
CTD PMID:18711747 PMID:19700661 PMID:25453207 PMID:31430510 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]; 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]]; Valproic Acid inhibits the reaction [Kainic Acid results in decreased expression of BCL2 protein]
Kainic Acid results in decreased expression of BCL2 mRNA
oridonin inhibits the reaction [Kainic Acid results in decreased expression of BCL2 mRNA]
CTD PMID:25453207 PMID:31430510 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
increases expression
EXP [Curcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]; [diacetylcurcumin co-treated with Manganese] inhibits the reaction [Kainic Acid results in increased expression of BDNF mRNA]
Kainic Acid results in increased expression of BDNF mRNA; Kainic Acid results in increased expression of BDNF protein
CTD PMID:1641125 PMID:9073163 PMID:11279263 PMID:16166269 PMID:17827730 PMID:19700661 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of BECN1 protein] CTD PMID:32057834 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G C1qb complement C1q B chain increases expression ISO Kainic Acid results in increased expression of C1QB mRNA CTD PMID:17997037 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G C4b complement C4B (Chido blood group) increases expression ISO Kainic Acid results in increased expression of C4B mRNA CTD PMID:17997037 NCBI chr20:4,302,344...4,316,752
Ensembl chr20:4,302,344...4,316,715
JBrowse link
G Calb1 calbindin 1 decreases expression ISO Kainic Acid results in decreased expression of CALB1 mRNA CTD PMID:17997037 NCBI chr 5:29,538,380...29,562,774
Ensembl chr 5:29,538,380...29,562,773
JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases expression ISO Kainic Acid results in decreased expression of CAMK4 mRNA CTD PMID:17997037 NCBI chr18:25,746,878...25,975,962
Ensembl chr18:25,749,098...25,965,957
JBrowse link
G Capns1 calpain, small subunit 1 increases expression EXP Kainic Acid results in increased expression of CAPNS1 mRNA CTD PMID:19700661 NCBI chr 1:91,058,528...91,064,880
Ensembl chr 1:88,652,446...88,657,845
JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage
increases expression
ISO
EXP
Kainic Acid results in increased activity of CASP3 protein
oridonin inhibits the reaction [Kainic Acid results in increased activity of CASP3 protein]
EPO protein inhibits the reaction [Kainic Acid results in increased expression of CASP3 protein]
Kainic Acid results in increased cleavage of CASP3 protein
Kainic Acid results in increased expression of CASP3 mRNA; Kainic Acid results in increased expression of CASP3 protein
4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]; 4-benzyl-2-methyl-1,2,4-thiadiazolidine-3,5-dione promotes the reaction [Valproic Acid inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]]; Minocycline inhibits the reaction [Kainic Acid results in increased activity of CASP3 protein]; Valproic Acid inhibits the reaction [Kainic Acid results in increased cleavage of CASP3 protein]
CTD PMID:16469440 PMID:18711747 PMID:19700661 PMID:25453207 PMID:31430510 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase decreases expression
decreases activity
multiple interactions
ISO
EXP
Kainic Acid results in decreased expression of CAT mRNA; Kainic Acid results in decreased expression of CAT protein
Kainic Acid results in decreased activity of CAT protein
oridonin inhibits the reaction [Kainic Acid results in decreased activity of CAT protein]
CTD PMID:29208536 PMID:31430510 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cck cholecystokinin decreases expression EXP Kainic Acid results in decreased expression of CCK protein CTD PMID:7774662 NCBI chr 8:130,120,525...130,127,515
Ensembl chr 8:130,120,523...130,127,392
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP Kainic Acid results in increased expression of CCL2 mRNA CTD PMID:19700661 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccne1 cyclin E1 increases expression EXP Kainic Acid results in increased expression of CCNE1 protein CTD PMID:12941380 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cd68 Cd68 molecule increases expression EXP Kainic Acid results in increased expression of CD68 mRNA CTD PMID:19700661 NCBI chr10:56,268,726...56,270,605
Ensembl chr10:56,268,720...56,270,640
JBrowse link
G Cdc42 cell division cycle 42 increases expression EXP Kainic Acid results in increased expression of CDC42 mRNA CTD PMID:19700661 NCBI chr 5:155,690,267...155,728,385
Ensembl chr 5:155,691,390...155,728,300
JBrowse link
G Cdh13 cadherin 13 increases expression ISO Kainic Acid results in increased expression of CDH13 mRNA CTD PMID:17997037 NCBI chr19:50,848,793...51,971,618
Ensembl chr19:50,848,736...51,972,103
JBrowse link
G Cdk2 cyclin dependent kinase 2 increases expression EXP Kainic Acid results in increased expression of CDK2 protein CTD PMID:12941380 NCBI chr 7:3,124,953...3,132,533
Ensembl chr 7:3,124,954...3,132,457
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO Kainic Acid results in increased expression of CEACAM1 mRNA CTD PMID:17997037 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Chgb chromogranin B increases expression EXP Kainic Acid results in increased expression of CHGB mRNA CTD PMID:9427505 NCBI chr 3:125,428,050...125,441,601
Ensembl chr 3:125,428,260...125,441,594
JBrowse link
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 increases expression EXP Kainic Acid results in increased expression of CITED2 mRNA CTD PMID:19700661 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786
JBrowse link
G Cnr1 cannabinoid receptor 1 increases expression EXP Kainic Acid results in increased expression of CNR1 mRNA CTD PMID:22079489 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnrip1 cannabinoid receptor interacting protein 1 increases expression EXP Kainic Acid results in increased expression of CNRIP1 mRNA CTD PMID:22079489 NCBI chr14:100,217,547...100,247,235
Ensembl chr14:100,217,289...100,247,235
JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Kainic Acid results in increased expression of COL1A1 mRNA CTD PMID:17997037 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 increases expression EXP Kainic Acid results in increased expression of CRHR1 mRNA CTD PMID:12093084 NCBI chr10:92,191,473...92,233,662
Ensembl chr10:92,191,718...92,232,645
JBrowse link
G Ctsb cathepsin B multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of CTSB protein] CTD PMID:32057834 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D multiple interactions
increases expression
EXP NADP inhibits the reaction [Kainic Acid results in increased expression of CTSD protein] CTD PMID:32057834 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Ctss cathepsin S increases expression ISO Kainic Acid results in increased expression of CTSS mRNA; Kainic Acid results in increased expression of CTSS protein CTD PMID:17997037 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Ctsz cathepsin Z increases expression ISO Kainic Acid results in increased expression of CTSZ mRNA CTD PMID:17997037 NCBI chr 3:172,527,107...172,537,877
Ensembl chr 3:172,527,107...172,537,877
JBrowse link
G Cycs cytochrome c, somatic increases localization
multiple interactions
increases expression
ISO
EXP
Kainic Acid results in increased localization of CYCS protein
Minocycline inhibits the reaction [Kainic Acid results in increased localization of CYCS protein]
Kainic Acid results in increased expression of CYCS mRNA
CTD PMID:16469440 PMID:19700661 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Dgcr6 DiGeorge syndrome critical region gene 6 decreases expression ISO Kainic Acid results in decreased expression of DGCR6 mRNA CTD PMID:17997037 NCBI chr11:87,076,205...87,081,306
Ensembl chr11:87,076,381...87,081,950
JBrowse link
G Dhx36 DEAH-box helicase 36 increases expression ISO Kainic Acid results in increased expression of DHX36 mRNA CTD PMID:17997037 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Diablo diablo, IAP-binding mitochondrial protein increases expression EXP Kainic Acid results in increased expression of DIABLO mRNA CTD PMID:19700661 NCBI chr12:38,490,230...38,503,344
Ensembl chr12:38,490,230...38,503,330
JBrowse link
G Drd2 dopamine receptor D2 decreases response to substance ISO DRD2 protein results in decreased susceptibility to Kainic Acid CTD PMID:11860278 NCBI chr 8:53,678,777...53,743,643
Ensembl chr 8:53,678,777...53,743,642
JBrowse link
G Egr1 early growth response 1 decreases expression
affects expression
ISO
EXP
Kainic Acid results in decreased expression of EGR1 mRNA
Kainic Acid affects the expression of EGR1 mRNA
CTD PMID:17997037 PMID:19700661 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Eif4a3 eukaryotic translation initiation factor 4A3 increases expression EXP Kainic Acid results in increased expression of EIF4A3 protein CTD PMID:17632064 NCBI chr10:108,415,201...108,425,195
Ensembl chr10:108,415,202...108,425,206
JBrowse link
G Emc3 ER membrane protein complex subunit 3 decreases expression ISO Kainic Acid results in decreased expression of EMC3 mRNA CTD PMID:17997037 NCBI chr 4:145,471,466...145,487,375
Ensembl chr 4:145,471,454...145,487,426
JBrowse link
G En2 engrailed homeobox 2 affects response to substance
decreases expression
ISO EN2 protein affects the susceptibility to Kainic Acid
Kainic Acid results in decreased expression of EN2 mRNA
CTD PMID:19186208 NCBI chr 4:438,668...444,508
Ensembl chr 4:438,668...444,501
JBrowse link
G Enc1 ectodermal-neural cortex 1 decreases expression ISO Kainic Acid results in decreased expression of ENC1 mRNA CTD PMID:17997037 NCBI chr 2:28,049,217...28,061,023
Ensembl chr 2:28,049,217...28,061,029
JBrowse link
G Epo erythropoietin multiple interactions ISO EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]; EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of CASP3 protein]; EPO protein inhibits the reaction [Kainic Acid results in increased expression of GFAP protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]] CTD PMID:18711747 NCBI chr12:22,274,828...22,278,268
Ensembl chr12:22,274,828...22,278,266
JBrowse link
G Epor erythropoietin receptor multiple interactions
decreases expression
ISO
EXP
EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of EPOR protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in decreased expression of JAK2 protein]]; EPOR protein promotes the reaction [EPO protein inhibits the reaction [Kainic Acid results in increased expression of BAX protein]] CTD PMID:18711747 NCBI chr 8:22,969,737...22,974,468
Ensembl chr 8:22,969,745...22,974,321
JBrowse link
G Etfb electron transfer flavoprotein subunit beta decreases expression ISO Kainic Acid results in decreased expression of ETFB mRNA CTD PMID:17997037 NCBI chr 1:98,472,776...98,486,940
Ensembl chr 1:98,472,745...98,486,976
JBrowse link
G Fbxw5 F-box and WD repeat domain containing 5 decreases expression ISO Kainic Acid results in decreased expression of FBXW5 mRNA CTD PMID:17997037 NCBI chr 3:2,726,705...2,731,213
Ensembl chr 3:2,727,254...2,731,212
JBrowse link
G Fgf2