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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:lithocholic acid sulfate
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Accession:CHEBI:35421 term browser browse the term
Definition:A steroid sulfate that is lithocholic acid in which the hydroxy hydrogen at position 3 has been replaced by a sulfo group.
Synonyms:exact_synonym: 3alpha-sulfooxy-5beta-cholan-24-oic acid
 related_synonym: (3alpha,5beta)-3-(sulfooxy)cholan-24-oic acid;   Formula=C24H40O6S;   InChI=1S/C24H40O6S/c1-15(4-9-22(25)26)19-7-8-20-18-6-5-16-14-17(30-31(27,28)29)10-12-23(16,2)21(18)11-13-24(19,20)3/h15-21H,4-14H2,1-3H3,(H,25,26)(H,27,28,29)/t15-,16-,17-,18+,19-,20+,21+,23+,24-/m1/s1;   InChIKey=AXDXVEYHEODSPN-HVATVPOCSA-N;   SMILES=C1[C@@]2([C@]3(CC[C@]4([C@]([C@@]3(CC[C@@]2(C[C@@H](C1)OS(O)(=O)=O)[H])[H])(CC[C@@]4([C@H](C)CCC(O)=O)[H])[H])C)[H])C;   lithocholic acid 3-sulfate;   sulfolithocholic acid
 xref: CAS:34669-57-3
 xref_mesh: MESH:C014202
 cyclic_relationship: is_conjugate_acid_of CHEBI:133940


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lithocholic acid sulfate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc1 ATP binding cassette subfamily C member 1 multiple interactions ISO sulfolithocholic acid inhibits the reaction [ABCC1 protein results in increased export of 2',7'-bis-(carboxypropyl)-5(6)-carboxyfluorescein] CTD PMID:16101123 NCBI chr10:528,961...655,179 JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions EXP sulfolithocholic acid binds to and results in decreased activity of GSTA4 protein CTD PMID:3954743 NCBI chr 8:79,066,967...79,084,193 JBrowse link
G Gstm1 glutathione S-transferase mu 1 multiple interactions EXP sulfolithocholic acid binds to and results in decreased activity of GSTM1 protein CTD PMID:3954743 NCBI chr 2:195,649,845...195,655,402 JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions EXP sulfolithocholic acid binds to and results in decreased activity of GSTM2 protein CTD PMID:3954743 NCBI chr 2:195,624,015...195,628,774 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19762
    role 19708
      chemical role 19254
        catalyst 8058
          sulfuric acid 8018
            sulfuric acid derivative 8018
              organic sulfate 1945
                steroid sulfate 61
                  lithocholic acid sulfate 4
Path 2
Term Annotations click to browse term
  CHEBI ontology 19762
    subatomic particle 19760
      composite particle 19760
        hadron 19760
          baryon 19760
            nucleon 19760
              atomic nucleus 19760
                atom 19760
                  main group element atom 19651
                    p-block element atom 19651
                      carbon group element atom 19570
                        carbon atom 19560
                          organic molecular entity 19560
                            organic molecule 19493
                              organic cyclic compound 19322
                                organic polycyclic compound 16508
                                  steroid 13042
                                    steroid fundamental parent 12676
                                      cholane 934
                                        cholanoid 934
                                          cholanic acids 918
                                            cholanic acid 918
                                              5beta-cholanic acid 918
                                                hydroxy-5beta-cholanic acid 918
                                                  bile acid 918
                                                    lithocholic acid 262
                                                      lithocholic acid sulfate 4
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