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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:monosaccharide
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Accession:CHEBI:35381 term browser browse the term
Definition:Parent monosaccharides are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H-[CHOH]n-C(=O)[CHOH]m-H with three or more carbon atoms. The generic term 'monosaccharide' (as opposed to oligosaccharide or polysaccharide) denotes a single unit, without glycosidic connection to other such units. It includes aldoses, dialdoses, aldoketoses, ketoses and diketoses, as well as deoxy sugars, provided that the parent compound has a (potential) carbonyl group.
Synonyms:exact_synonym: monosaccharides
 related_synonym: Monosaccharid;   Monosacharid;   monosacarido;   monosacaridos
 alt_id: CHEBI:25407;   CHEBI:6984
 xref: KEGG:C06698


show annotations for term's descendants           Sort by:
2-deoxy-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP [Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein; Quercetin inhibits the reaction [[Antimycin A co-treated with Deoxyglucose] results in increased expression of BAX protein] CTD PMID:25087994 NCBI chr 6:54,222,341...54,228,150
Ensembl chr 6:54,222,336...54,228,140 		JBrowse link
G MTOR mechanistic target of rapamycin kinase multiple interactions EXP [Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein; Quercetin promotes the reaction [[Antimycin A co-treated with Deoxyglucose] results in decreased phosphorylation of MTOR protein] CTD PMID:25087994 NCBI chr 6:71,286,989...71,412,913
Ensembl chr 6:71,286,989...71,412,888 		JBrowse link
G NOS3 nitric oxide synthase 3 decreases expression EXP Deoxyglucose results in decreased expression of NOS3 mRNA CTD PMID:11382920 NCBI chr18:6,209,218...6,228,912
Ensembl chr18:6,209,158...6,228,943 		JBrowse link
3',5'-cyclic AMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP7B ATPase copper transporting beta multiple interactions EXP Cyclic AMP inhibits the reaction [Copper binds to ATP7B protein] CTD PMID:21084060 NCBI chr11:15,892,549...15,942,070
Ensembl chr11:15,876,612...15,942,064 		JBrowse link
G CALCB calcitonin-related polypeptide beta increases abundance EXP CALCA protein results in increased abundance of Cyclic AMP CTD PMID:18463244 NCBI chr 2:44,043,135...44,048,651 JBrowse link
G DUOX2 dual oxidase 2 increases expression EXP Cyclic AMP results in increased expression of DUOX2 mRNA CTD PMID:10601291 NCBI chr 1:126,620,468...126,641,406
Ensembl chr 1:126,620,510...126,641,406 		JBrowse link
G GCG glucagon affects response to substance
increases abundance		 EXP Cyclic AMP affects the susceptibility to GCG protein
GCG protein results in increased abundance of Cyclic AMP		 CTD PMID:6253273 NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,560...68,810,242 		JBrowse link
G GNRH1 gonadotropin releasing hormone 1 multiple interactions
increases abundance		 EXP [Cobalt binds to GNRH1 protein] which results in increased abundance of Cyclic AMP
GNRH1 protein results in increased abundance of Cyclic AMP		 CTD PMID:15833593 NCBI chr14:9,442,971...9,447,521
Ensembl chr14:9,442,971...9,453,035 		JBrowse link
3',5'-cyclic GMP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PDE5A phosphodiesterase 5A increases degradation EXP PDE5 protein results in increased degradation of Cyclic GMP CTD PMID:18669600 NCBI chr 8:104,270,858...104,420,955
Ensembl chr 8:104,270,881...104,420,953 		JBrowse link
G PDE6C phosphodiesterase 6C increases degradation EXP PDE6C protein results in increased degradation of Cyclic GMP CTD PMID:18669600 NCBI chr14:105,010,974...105,122,628
Ensembl chr14:105,050,691...105,122,421 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 increases activity EXP Cyclic GMP results in increased activity of PRKG1 protein CTD PMID:18037907 NCBI chr14:97,558,531...98,793,080
Ensembl chr14:97,558,533...98,793,010 		JBrowse link
adenosine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYL9 myosin light chain 9 decreases phosphorylation
multiple interactions		 EXP Adenosine results in decreased phosphorylation of MYL9 protein
8-phenyltheophylline inhibits the reaction [Adenosine results in decreased phosphorylation of MYL9 protein]		 CTD PMID:10942722 NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,293 		JBrowse link
aldehydo-D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions		 EXP Glucose results in increased expression of ACACA mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]		 CTD PMID:25827716 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712 		JBrowse link
G FASN fatty acid synthase multiple interactions
increases expression		 EXP MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] CTD PMID:25827716 NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561 		JBrowse link
G INS insulin multiple interactions
increases transport		 EXP INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:8048502 PMID:8699633 PMID:20622751 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G LOC102165256 V-type proton ATPase subunit G 1 pseudogene decreases expression EXP Glucose results in decreased expression of ATP6V1G1 mRNA CTD PMID:16313995 NCBI chr 7:19,272,032...19,272,926 JBrowse link
G MLXIP MLX interacting protein increases expression
multiple interactions		 EXP Glucose results in increased expression of MLXIP mRNA
Glucose promotes the reaction [T0901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]		 CTD PMID:25827716 NCBI chr14:30,575,098...30,646,275
Ensembl chr14:30,577,661...30,646,243 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein] CTD PMID:16949779 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
increases expression		 EXP T0901317 promotes the reaction [Glucose results in increased expression of NR1H3 mRNA] CTD PMID:25827716 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,315,282...15,334,820 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of PTGS2 protein] CTD PMID:16949779 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases transport EXP SLC2A1 protein results in increased transport of Glucose CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,535,440...168,560,867 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 EXP MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] CTD PMID:25827716 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
ATP term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCL2 BCL2 apoptosis regulator increases expression
multiple interactions		 EXP Adenosine Triphosphate results in increased expression of BCL2 protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of BCL2 protein]		 CTD PMID:17997382 NCBI chr 1:158,337,403...158,518,214
Ensembl chr 1:158,337,522...158,518,879 		JBrowse link
G CASP8 caspase 8 increases activity
multiple interactions		 EXP Adenosine Triphosphate results in increased activity of CASP8 protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased activity of CASP8 protein]		 CTD PMID:17997382 NCBI chr15:104,923,659...104,948,470
Ensembl chr15:104,923,953...104,948,468 		JBrowse link
G CYCS cytochrome c, somatic affects localization
multiple interactions		 EXP Adenosine Triphosphate affects the localization of CYCS protein
[Calcium co-treated with Phosphates co-treated with Adenosine Triphosphate] affects the localization of CYCS protein; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate affects the localization of CYCS protein]		 CTD PMID:16489745 PMID:17997382 NCBI chr18:47,169,921...47,172,212
Ensembl chr18:47,169,866...47,173,866 		JBrowse link
G MYL9 myosin light chain 9 decreases phosphorylation
multiple interactions		 EXP Adenosine Triphosphate results in decreased phosphorylation of MYL9 protein
1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]]; Adenosine Triphosphate promotes the reaction [calyculin A results in increased phosphorylation of MYL9 protein]		 CTD PMID:10942722 NCBI chr17:39,788,165...39,795,240
Ensembl chr17:39,788,199...39,795,293 		JBrowse link
G TNF tumor necrosis factor increases expression
multiple interactions		 EXP Adenosine Triphosphate results in increased expression of TNF protein
tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [Adenosine Triphosphate results in increased expression of TNF protein]		 CTD PMID:17997382 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
bucladesine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 increases expression EXP Bucladesine results in increased expression of ATP1A1 protein CTD PMID:28438630 NCBI chr 4:104,353,506...104,384,321
Ensembl chr 4:104,353,508...104,384,547 		JBrowse link
D-glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions		 EXP Glucose results in increased expression of ACACA mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]		 CTD PMID:25827716 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712 		JBrowse link
G FASN fatty acid synthase multiple interactions
increases expression		 EXP MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA] CTD PMID:25827716 NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561 		JBrowse link
G INS insulin multiple interactions
increases transport		 EXP INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:8048502 PMID:8699633 PMID:20622751 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G LOC102165256 V-type proton ATPase subunit G 1 pseudogene decreases expression EXP Glucose results in decreased expression of ATP6V1G1 mRNA CTD PMID:16313995 NCBI chr 7:19,272,032...19,272,926 JBrowse link
G MLXIP MLX interacting protein increases expression
multiple interactions		 EXP Glucose results in increased expression of MLXIP mRNA
Glucose promotes the reaction [T0901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]		 CTD PMID:25827716 NCBI chr14:30,575,098...30,646,275
Ensembl chr14:30,577,661...30,646,243 		JBrowse link
G NOS2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP Glucose results in increased expression of NOS2 protein
Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein]		 CTD PMID:16949779 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 multiple interactions
increases expression		 EXP T0901317 promotes the reaction [Glucose results in increased expression of NR1H3 mRNA] CTD PMID:25827716 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,315,282...15,334,820 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions		 EXP Glucose results in increased expression of PTGS2 protein
Kangen-karyu inhibits the reaction [Glucose results in increased expression of PTGS2 protein]		 CTD PMID:16949779 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases transport EXP SLC2A1 protein results in increased transport of Glucose CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,535,440...168,560,867 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 multiple interactions
increases expression		 EXP MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA] CTD PMID:25827716 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
glucose term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha increases expression
multiple interactions		 EXP Glucose results in increased expression of ACACA mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]		 CTD PMID:25827716 NCBI chr12:38,580,916...38,875,067
Ensembl chr12:38,581,457...38,824,712 		JBrowse link
G FASN fatty acid synthase increases expression
multiple interactions		 EXP Glucose results in increased expression of FASN mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]		 CTD PMID:25827716 NCBI chr12:922,405...937,560
Ensembl chr12:920,509...937,561 		JBrowse link
G INS insulin multiple interactions
increases transport		 EXP INS protein promotes the reaction [AZ 002 results in increased uptake of Glucose]; oxophenylarsine inhibits the reaction [INS protein results in increased transport of Glucose]; Sirolimus inhibits the reaction [Glucose results in increased secretion of INS protein] CTD PMID:8048502 PMID:8699633 PMID:20622751 NCBI chr 2:1,496,842...1,498,052
Ensembl chr 2:1,496,842...1,497,841 		JBrowse link
G LOC102165256 V-type proton ATPase subunit G 1 pseudogene decreases expression EXP Glucose results in decreased expression of ATP6V1G1 mRNA CTD PMID:16313995 NCBI chr 7:19,272,032...19,272,926 JBrowse link
G MLXIP MLX interacting protein multiple interactions
increases expression		 EXP Glucose promotes the reaction [T0901317 results in increased expression of MLXIP mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of ACACA mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of FASN mRNA]; MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]
Glucose results in increased expression of MLXIP mRNA		 CTD PMID:25827716 NCBI chr14:30,575,098...30,646,275
Ensembl chr14:30,577,661...30,646,243 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions
increases expression		 EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of NOS2 protein] CTD PMID:16949779 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 increases expression
multiple interactions		 EXP Glucose results in increased expression of NR1H3 mRNA
T0901317 promotes the reaction [Glucose results in increased expression of NR1H3 mRNA]		 CTD PMID:25827716 NCBI chr 2:15,315,283...15,336,785
Ensembl chr 2:15,315,282...15,334,820 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions
increases expression		 EXP Kangen-karyu inhibits the reaction [Glucose results in increased expression of PTGS2 protein] CTD PMID:16949779 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 increases transport EXP SLC2A1 protein results in increased transport of Glucose CTD PMID:12081571 NCBI chr 6:168,535,398...168,561,170
Ensembl chr 6:168,535,440...168,560,867 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression
multiple interactions		 EXP Glucose results in increased expression of SREBF1 mRNA
MLXIP protein affects the reaction [Glucose results in increased expression of SREBF1 mRNA]		 CTD PMID:25827716 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
L-ascorbic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALPL alkaline phosphatase, biomineralization associated multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of ALPL mRNA CTD PMID:30481989 NCBI chr 6:79,589,695...79,649,646
Ensembl chr 6:79,589,045...79,649,644 		JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of BCL2L1 mRNA CTD PMID:30481989 NCBI chr17:35,366,139...35,415,798
Ensembl chr17:35,366,143...35,414,694 		JBrowse link
G CASP3 caspase 3 multiple interactions EXP [Troglitazone co-treated with beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CASP3 mRNA CTD PMID:30481989 NCBI chr15:45,744,320...45,753,252
Ensembl chr15:45,742,751...45,764,213 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CEBPA mRNA] CTD PMID:30481989 NCBI chr 6:43,083,200...43,085,884
Ensembl chr 6:43,083,207...43,085,836 		JBrowse link
G COL1A1 collagen type I alpha 1 chain multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of COL1A1 mRNA CTD PMID:30481989 NCBI chr12:26,379,087...26,397,180
Ensembl chr12:26,379,090...26,397,004 		JBrowse link
G CTNNB1 catenin beta 1 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of CTNNB1 mRNA] CTD PMID:30481989 NCBI chr13:25,163,550...25,208,314
Ensembl chr13:25,164,277...25,208,311 		JBrowse link
G FABP4 fatty acid binding protein 4 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of FABP4 mRNA] CTD PMID:30481989 NCBI chr 4:55,096,400...55,101,209
Ensembl chr 4:55,096,404...55,101,896 		JBrowse link
G IGF1 insulin like growth factor 1 multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1 mRNA] CTD PMID:30481989 NCBI chr 5:81,762,027...81,909,253
Ensembl chr 5:81,775,970...81,848,033 		JBrowse link
G IGF1R insulin like growth factor 1 receptor multiple interactions EXP [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of IGF1R mRNA] CTD PMID:30481989 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of PPARG mRNA] CTD PMID:30481989 NCBI chr13:68,301,566...68,433,951
Ensembl chr13:68,302,322...68,433,944 		JBrowse link
G RUNX2 RUNX family transcription factor 2 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of RUNX2 mRNA CTD PMID:30481989 NCBI chr 7:40,106,581...40,353,304
Ensembl chr 7:40,106,532...40,460,687 		JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions EXP 2,2-bis(4-glycidyloxyphenyl)propane promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA]; [beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA; Troglitazone promotes the reaction [[beta-glycerophosphoric acid co-treated with Ascorbic Acid co-treated with Dexamethasone] results in increased expression of SPP1 mRNA] CTD PMID:30481989 NCBI chr 8:131,077,786...131,085,334
Ensembl chr 8:131,077,786...131,085,340 		JBrowse link
mogroside V term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL18 interleukin 18 multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of IL18 mRNA] CTD PMID:35134483 NCBI chr 9:39,839,959...39,861,258
Ensembl chr 9:39,834,973...39,861,219 		JBrowse link
G LOC110258578 interleukin-1 beta-like increases expression EXP mogroside V results in increased expression of IL1B mRNA CTD PMID:35134483
G NLRP3 NLR family pyrin domain containing 3 multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of NLRP3 protein] CTD PMID:35134483 NCBI chr 2:56,892,241...56,977,412
Ensembl chr 2:56,892,243...56,977,228 		JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of NOS2 mRNA] CTD PMID:35134483 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA] CTD PMID:35134483 NCBI chr 9:127,850,164...127,858,866
Ensembl chr 9:127,850,015...127,858,884 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein] CTD PMID:35134483 NCBI chr 2:6,594,869...6,602,684
Ensembl chr 2:6,593,969...6,603,469 		JBrowse link
G TNF tumor necrosis factor multiple interactions EXP mogroside V inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA] CTD PMID:35134483 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
neomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLC5A1 solute carrier family 5 member 1 decreases expression EXP Neomycin results in decreased expression of SLC5A1 mRNA; Neomycin results in decreased expression of SLC5A1 protein CTD PMID:12927799 NCBI chr14:48,566,400...48,704,145
Ensembl chr14:48,628,224...48,705,841 		JBrowse link
notoginsenoside R1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL10 interleukin 10 decreases expression EXP notoginsenoside R1 results in decreased expression of IL10 protein CTD PMID:25721049 NCBI chr 9:67,400,727...67,405,941
Ensembl chr 9:67,400,728...67,405,378 		JBrowse link
G IL4 interleukin 4 decreases expression EXP notoginsenoside R1 results in decreased expression of IL4 protein CTD PMID:25721049 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
tilmicosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1A2 solute carrier organic anion transporter family member 1A2 multiple interactions EXP tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; tilmicosin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730 		JBrowse link
troleandomycin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP3A29 cytochrome P450 family 3 subfamily A member 29 multiple interactions EXP Troleandomycin inhibits the reaction [CYP3A29 protein results in increased chemical synthesis of 6 beta-hydroxytestosterone]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased hydroxylation of Testosterone]; Troleandomycin inhibits the reaction [CYP3A29 protein results in increased oxidation of Nifedipine] CTD PMID:20863320 NCBI chr 3:6,738,502...6,778,121
Ensembl chr 3:6,738,486...6,778,944 		JBrowse link
tylosin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SLCO1A2 solute carrier organic anion transporter family member 1A2 multiple interactions EXP Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of estrone sulfate]; Tylosin inhibits the reaction [SLCO1A2 protein results in increased uptake of Taurocholic Acid] CTD PMID:31287969 NCBI chr 5:52,020,303...52,133,132
Ensembl chr 5:52,049,443...52,129,730 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 5066
    chemical entity 5066
      atom 5057
        nonmetal atom 5019
          oxygen atom 4896
            oxygen molecular entity 4896
              organooxygen compound 4703
                carbohydrates and carbohydrate derivatives 123
                  carbohydrate 123
                    monosaccharide 48
                      (-)-2,3,4-Trihydroxybutanamide 0
                      (3,4,5,6-tetrahydroxyoxan-2-yl)methyl acetate 0
                      1,2,6,10-tetrahydroxy-3,9-epoxy-14-nor-5(15)-eudesmane 0
                      1-Methoxy-3-methylene-2-pentanone 0
                      1-deoxy-N-acetylglucosamine 0
                      1-methyl 3-(3,4,5,6-tetrahydroxyoxan-2-yl)methyl propanedioate 0
                      2,3-Dihydroxybutanamide 0
                      2-Hydroxy-4-methylthio-butyrate 0
                      2-Hydroxyhexan-3-one 0
                      2-\{[methyl(2,3,4,5,6-pentahydroxyhexyl)amino]methylidene\}malononitrile 0
                      2S-hydroxyhexan-3-one 0
                      3-Hydroxyheptan-2-one 0
                      3-oxo-3-[(3,4,5,6-tetrahydroxyoxan-2-yl)methoxy]propanoic acid 0
                      3R-Hydroxyhexan-2-one 0
                      3S-Hydroxyhexan-2-one 0
                      5-Hydroxy-4-octanone 0
                      6-Hydroxyphomodiol 0
                      7-(1,3-Cyclohexadienyl)-5-hydroxy-2,6-dimethyl-2-hepten-4-one 0
                      Brevione E 0
                      Catathelasmol D 0
                      D-altro-D-manno-Heptose 0
                      Galacto-hexodialdose 0
                      Heliconol A 0
                      LSM-36737 0
                      LSM-36764 0
                      Lithocarin D 0
                      Muscarine 0
                      N-acetyl-3-amino-3,6-dideoxy-D-galactose 0
                      Penasin A 0
                      Penasin B 0
                      Penasin C 0
                      Penasin D 0
                      Penasin E 0
                      Phomactin A 0
                      Phomodiol 0
                      Psicopyranose 0
                      Sphydrofuran 0
                      Spliceostatin H 0
                      aldose + 25
                      anhydro sugar + 0
                      b-Mercaptolactic acid 0
                      beta-D-Glucopyranose,1-thio-,1-(5-(methylsulfinyl)-N-(sulfooxy)-4-pentenimidate 0
                      dialdose + 0
                      diketoaldonic acid + 0
                      erythro-Tetrodialdose 0
                      heptose + 0
                      hexose + 21
                      ketoaldonic acid + 12
                      ketoaldose + 0
                      ketose + 0
                      mannite hexanitrate 0
                      monosaccharide derivative + 16
                      octose + 0
                      pentose + 14
                      tetrose + 0
                      triose + 0
                      uronic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 5066
    subatomic particle 5057
      composite particle 5057
        hadron 5057
          baryon 5057
            nucleon 5057
              atomic nucleus 5057
                atom 5057
                  main group element atom 5026
                    p-block element atom 5023
                      carbon group element atom 4940
                        carbon atom 4939
                          organic molecular entity 4939
                            heteroorganic entity 4779
                              organochalcogen compound 4741
                                organooxygen compound 4703
                                  carbohydrates and carbohydrate derivatives 123
                                    carbohydrate 123
                                      monosaccharide 48
                                        (-)-2,3,4-Trihydroxybutanamide 0
                                        (3,4,5,6-tetrahydroxyoxan-2-yl)methyl acetate 0
                                        1,2,6,10-tetrahydroxy-3,9-epoxy-14-nor-5(15)-eudesmane 0
                                        1-Methoxy-3-methylene-2-pentanone 0
                                        1-deoxy-N-acetylglucosamine 0
                                        1-methyl 3-(3,4,5,6-tetrahydroxyoxan-2-yl)methyl propanedioate 0
                                        2,3-Dihydroxybutanamide 0
                                        2-Hydroxy-4-methylthio-butyrate 0
                                        2-Hydroxyhexan-3-one 0
                                        2-\{[methyl(2,3,4,5,6-pentahydroxyhexyl)amino]methylidene\}malononitrile 0
                                        2S-hydroxyhexan-3-one 0
                                        3-Hydroxyheptan-2-one 0
                                        3-oxo-3-[(3,4,5,6-tetrahydroxyoxan-2-yl)methoxy]propanoic acid 0
                                        3R-Hydroxyhexan-2-one 0
                                        3S-Hydroxyhexan-2-one 0
                                        5-Hydroxy-4-octanone 0
                                        6-Hydroxyphomodiol 0
                                        7-(1,3-Cyclohexadienyl)-5-hydroxy-2,6-dimethyl-2-hepten-4-one 0
                                        Brevione E 0
                                        Catathelasmol D 0
                                        D-altro-D-manno-Heptose 0
                                        Galacto-hexodialdose 0
                                        Heliconol A 0
                                        LSM-36737 0
                                        LSM-36764 0
                                        Lithocarin D 0
                                        Muscarine 0
                                        N-acetyl-3-amino-3,6-dideoxy-D-galactose 0
                                        Penasin A 0
                                        Penasin B 0
                                        Penasin C 0
                                        Penasin D 0
                                        Penasin E 0
                                        Phomactin A 0
                                        Phomodiol 0
                                        Psicopyranose 0
                                        Sphydrofuran 0
                                        Spliceostatin H 0
                                        aldose + 25
                                        anhydro sugar + 0
                                        b-Mercaptolactic acid 0
                                        beta-D-Glucopyranose,1-thio-,1-(5-(methylsulfinyl)-N-(sulfooxy)-4-pentenimidate 0
                                        dialdose + 0
                                        diketoaldonic acid + 0
                                        erythro-Tetrodialdose 0
                                        heptose + 0
                                        hexose + 21
                                        ketoaldonic acid + 12
                                        ketoaldose + 0
                                        ketose + 0
                                        mannite hexanitrate 0
                                        monosaccharide derivative + 16
                                        octose + 0
                                        pentose + 14
                                        tetrose + 0
                                        triose + 0
                                        uronic acid + 0
paths to the root