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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:1,2-dichlorobenzene
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Accession:CHEBI:35290 term browser browse the term
Definition:A dichlorobenzene carrying chloro substituents at positions 1 and 2.
Synonyms:related_synonym: 1,2-dichlorbenzene;   2-dichlorobenzene;   Formula=C6H4Cl2;   InChI=1S/C6H4Cl2/c7-5-3-1-2-4-6(5)8/h1-4H;   InChIKey=RFFLAFLAYFXFSW-UHFFFAOYSA-N;   ODB;   ODCB;   SMILES=Clc1ccccc1Cl;   o-Dichlorobenzene;   o-dichlorbenzene;   o-dichlorbenzol;   o-dichlorobenzol;   ortho-dichlorobenzene;   orthodichlorobenzol
 alt_id: CHEBI:32498;   CHEBI:34045
 xref: Beilstein:606078;   CAS:95-50-1;   Gmelin:82493;   KEGG:C14328
 xref_mesh: MESH:C004726
 xref: MetaCyc:O-DICHLOROBENZENE;   PDBeChem:YAN;   PMID:10048141;   PMID:10698672;   PMID:14168435;   PMID:15792297;   PMID:22165224;   Reaxys:606078;   Wikipedia:1\,2-Dichlorobenzene


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1,2-dichlorobenzene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cat catalase multiple interactions EXP CAT protein inhibits the reaction [[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2D2 protein] CTD PMID:24713513 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 increases expression EXP 2-dichlorobenzene results in increased expression of CXCL1 protein CTD PMID:12915711 NCBI chr14:18,743,678...18,745,457
Ensembl chr14:18,743,685...18,745,457
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases oxidation
multiple interactions
ISO
EXP
CYP1A1 protein results in increased oxidation of 2-dichlorobenzene
[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP1A1 protein
CTD PMID:7747284, PMID:24713513 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases oxidation ISO CYP1A2 protein results in increased oxidation of 2-dichlorobenzene CTD PMID:7747284 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp2d2 cytochrome P450, family 2, subfamily d, polypeptide 2 multiple interactions EXP [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2D2 protein; CAT protein inhibits the reaction [[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2D2 protein] CTD PMID:24713513 NCBI chr 7:123,651,827...123,655,896
Ensembl chr 7:123,651,827...123,655,896
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 increases oxidation
increases metabolic processing
multiple interactions
ISO
EXP
CYP2E1 protein results in increased oxidation of 2-dichlorobenzene
CYP2E1 protein results in increased metabolism of 2-dichlorobenzene
[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene; dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]
[2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP2E1 protein; [Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene; dihydroxyethyldithiocarbamate inhibits the reaction [[Benzene results in increased activity of CYP2E1 protein] which results in increased metabolism of 2-dichlorobenzene]
CTD PMID:7747284, PMID:9817075, PMID:24713513 NCBI chr 1:213,511,892...213,522,195
Ensembl chr 1:213,511,874...213,535,542
JBrowse link
G Cyp3a62 cytochrome P450, family 3, subfamily a, polypeptide 62 multiple interactions EXP [2-dichlorobenzene analog co-treated with NADP] results in decreased activity of CYP3A62 protein CTD PMID:24713513 NCBI chr12:18,679,809...18,709,397
Ensembl chr12:18,678,594...18,709,397
JBrowse link
G Glud1 glutamate dehydrogenase 1 increases activity
multiple interactions
EXP
ISO
2-dichlorobenzene results in increased activity of GLUD1 protein
cyclohexanone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein]; methyl isobutyl ketone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein]; methylethyl ketone promotes the reaction [2-dichlorobenzene results in increased activity of GLUD1 protein]
CTD PMID:2554539, PMID:3012827 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Gpt glutamic--pyruvic transaminase increases activity EXP 2-dichlorobenzene results in increased activity of GPT protein CTD PMID:8440869 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Gstp1 glutathione S-transferase pi 1 affects localization
decreases activity
ISO 2-dichlorobenzene affects the localization of GSTP1 protein
2-dichlorobenzene results in decreased activity of GSTP1 protein
CTD PMID:18409811 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression EXP 2-dichlorobenzene results in increased expression of HRAS mRNA CTD PMID:10614693 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity
increases phosphorylation
EXP 2-dichlorobenzene results in increased activity of JUN protein
2-dichlorobenzene results in increased phosphorylation of JUN protein
CTD PMID:12915711 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression EXP 2-dichlorobenzene results in increased expression of MYC mRNA CTD PMID:10614693 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Nefh neurofilament heavy affects expression EXP 2-dichlorobenzene affects the expression of NEFH mRNA CTD PMID:22954530 NCBI chr14:85,181,572...85,191,557
Ensembl chr14:85,181,572...85,191,557
JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP 2-dichlorobenzene results in increased expression of PCNA protein CTD PMID:9184194 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Sord sorbitol dehydrogenase increases activity EXP 2-dichlorobenzene results in increased activity of SORD protein CTD PMID:3012827 NCBI chr 3:114,176,127...114,207,368
Ensembl chr 3:114,176,309...114,207,366
JBrowse link
G Tnf tumor necrosis factor increases expression ISO 2-dichlorobenzene results in increased expression of TNF protein CTD PMID:9574806 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
3,4-dichloroaniline term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP 3,4-dichloroaniline results in decreased expression of ACSS2 mRNA CTD PMID:24172598 NCBI chr 3:151,032,925...151,075,856
Ensembl chr 3:151,032,952...151,075,856
JBrowse link
G Acvr1c activin A receptor type 1C increases expression ISO 3,4-dichloroaniline results in increased expression of ACVR1C mRNA CTD PMID:24172598 NCBI chr 3:44,272,859...44,342,501
Ensembl chr 3:44,270,653...44,342,355
JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression ISO 3,4-dichloroaniline results in increased expression of ADAMTS9 mRNA CTD PMID:24172598 NCBI chr 4:124,660,254...124,860,997
Ensembl chr 4:124,660,262...124,858,250
JBrowse link
G Ajuba ajuba LIM protein decreases expression ISO 3,4-dichloroaniline results in decreased expression of AJUBA mRNA CTD PMID:24172598 NCBI chr15:33,208,210...33,218,456
Ensembl chr15:33,208,216...33,218,456
JBrowse link
G Akr1c2 aldo-keto reductase family 1, member C2 increases expression ISO 3,4-dichloroaniline results in increased expression of AKR1C2 mRNA CTD PMID:24172598 NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
JBrowse link
G Akr1c3 aldo-keto reductase family 1, member C3 increases expression ISO 3,4-dichloroaniline results in increased expression of AKR1C3 mRNA CTD PMID:24172598 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family, member A3 increases expression EXP 3,4-dichloroaniline results in increased expression of ALDH1A3 mRNA CTD PMID:24172598 NCBI chr 1:127,302,920...127,337,828
Ensembl chr 1:127,301,128...127,337,882
JBrowse link
G Anln anillin, actin binding protein decreases expression ISO 3,4-dichloroaniline results in decreased expression of ANLN mRNA CTD PMID:24172598 NCBI chr 8:23,336,455...23,397,122
Ensembl chr 8:23,337,621...23,390,773
JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E decreases expression ISO 3,4-dichloroaniline results in decreased expression of ANP32E mRNA CTD PMID:24172598 NCBI chr 2:198,040,573...198,057,005
Ensembl chr 2:198,040,536...198,057,003
JBrowse link
G Antxr2 ANTXR cell adhesion molecule 2 increases expression ISO 3,4-dichloroaniline results in increased expression of ANTXR2 mRNA CTD PMID:24172598 NCBI chr14:13,191,716...13,331,286
Ensembl chr14:13,192,347...13,274,978
JBrowse link
G Aox1 aldehyde oxidase 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of AOX1 mRNA CTD PMID:24172598 NCBI chr 9:64,929,682...65,007,872
Ensembl chr 9:64,929,721...65,007,870
JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP 3,4-dichloroaniline results in increased expression of ASS1 mRNA CTD PMID:24172598 NCBI chr 3:10,327,411...10,375,847
Ensembl chr 3:10,327,414...10,375,826
JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO 3,4-dichloroaniline results in increased expression of ATF3 mRNA CTD PMID:24172598 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atp6v0d2 ATPase H+ transporting V0 subunit D2 increases expression ISO 3,4-dichloroaniline results in increased expression of ATP6V0D2 mRNA CTD PMID:24172598 NCBI chr 5:33,843,591...33,892,446
Ensembl chr 5:33,843,519...33,892,462
JBrowse link
G Axl Axl receptor tyrosine kinase decreases expression ISO 3,4-dichloroaniline results in decreased expression of AXL mRNA CTD PMID:24172598 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Bmp6 bone morphogenetic protein 6 increases expression ISO 3,4-dichloroaniline results in increased expression of BMP6 mRNA CTD PMID:24172598 NCBI chr17:26,955,142...27,112,820
Ensembl chr17:26,955,142...27,112,820
JBrowse link
G C3 complement C3 increases expression ISO
EXP
3,4-dichloroaniline results in increased expression of C3 mRNA CTD PMID:24172598 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Ccdc113 coiled-coil domain containing 113 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CCDC113 mRNA CTD PMID:24172598 NCBI chr19:9,912,124...9,932,183
Ensembl chr19:9,912,183...9,931,930
JBrowse link
G Ccn1 cellular communication network factor 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CCN1 mRNA CTD PMID:24172598 NCBI chr 2:251,529,354...251,532,312
Ensembl chr 2:251,529,354...251,532,312
JBrowse link
G Ccn2 cellular communication network factor 2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CCN2 mRNA CTD PMID:24172598 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Cdcp1 CUB domain containing protein 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CDCP1 mRNA CTD PMID:24172598 NCBI chr 8:132,260,007...132,296,661
Ensembl chr 8:132,260,029...132,296,661
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CEACAM1 mRNA CTD PMID:24172598 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cep126 centrosomal protein 126 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CEP126 mRNA CTD PMID:24172598 NCBI chr 8:6,237,838...6,305,127
Ensembl chr 8:6,255,850...6,305,033
JBrowse link
G Cfap20dc CFAP20 domain containing increases expression ISO 3,4-dichloroaniline results in increased expression of CFAP20DC mRNA CTD PMID:24172598 NCBI chr15:17,664,838...17,918,216
Ensembl chr15:17,775,692...17,924,302
JBrowse link
G Cfap300 cilia and flagella associated protein 300 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CFAP300 mRNA CTD PMID:24172598 NCBI chr 8:6,218,391...6,236,438
Ensembl chr 8:6,218,393...6,235,967
JBrowse link
G Cldn11 claudin 11 decreases expression ISO 3,4-dichloroaniline results in decreased expression of CLDN11 mRNA CTD PMID:24172598 NCBI chr 2:115,823,541...115,836,846
Ensembl chr 2:115,823,538...115,836,846
JBrowse link
G Clgn calmegin increases expression ISO 3,4-dichloroaniline results in increased expression of CLGN mRNA CTD PMID:24172598 NCBI chr19:24,545,257...24,578,527
Ensembl chr19:24,545,318...24,576,798
JBrowse link
G Cndp1 carnosine dipeptidase 1 increases expression EXP 3,4-dichloroaniline results in increased expression of CNDP1 mRNA CTD PMID:24172598 NCBI chr18:81,466,717...81,512,841
Ensembl chr18:81,466,716...81,499,051
JBrowse link
G Col8a1 collagen type VIII alpha 1 chain decreases expression ISO 3,4-dichloroaniline results in decreased expression of COL8A1 mRNA CTD PMID:24172598 NCBI chr11:44,877,690...45,006,203
Ensembl chr11:44,877,859...45,007,891
JBrowse link
G Cstb cystatin B increases expression ISO 3,4-dichloroaniline results in increased expression of CSTB mRNA CTD PMID:24172598 NCBI chr20:10,966,357...10,968,399
Ensembl chr20:10,966,331...10,968,432
JBrowse link
G Ctse cathepsin E increases expression EXP 3,4-dichloroaniline results in increased expression of CTSE mRNA CTD PMID:24172598 NCBI chr13:48,426,833...48,449,493
Ensembl chr13:48,426,820...48,449,490
JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression EXP 3,4-dichloroaniline results in increased expression of CX3CL1 mRNA CTD PMID:24172598 NCBI chr19:10,644,267...10,654,861
Ensembl chr19:10,644,244...10,653,800
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression EXP 3,4-dichloroaniline results in increased expression of CXCL5 mRNA CTD PMID:24172598 NCBI chr14:18,860,201...18,920,839
Ensembl chr14:18,860,264...18,862,407
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP1A1 mRNA; 3,4-dichloroaniline results in increased expression of CYP1A1 protein CTD PMID:21784029, PMID:24172598 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP1A2 mRNA; 3,4-dichloroaniline results in increased expression of CYP1A2 protein CTD PMID:21784029 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP1B1 mRNA CTD PMID:24172598 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 increases expression ISO 3,4-dichloroaniline results in increased expression of CYP4F3 mRNA CTD PMID:24172598 NCBI chr16:19,501,680...19,528,935
Ensembl chr16:19,410,810...19,528,999
JBrowse link
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 increases expression ISO 3,4-dichloroaniline results in increased expression of DNAJB9 mRNA CTD PMID:24172598 NCBI chr 6:64,165,913...64,170,122
Ensembl chr 6:64,165,913...64,170,151
JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression ISO 3,4-dichloroaniline results in increased expression of DNER mRNA CTD PMID:24172598 NCBI chr 9:91,965,866...92,291,172
Ensembl chr 9:91,965,866...92,291,220
JBrowse link
G Dpp4 dipeptidylpeptidase 4 increases expression ISO 3,4-dichloroaniline results in increased expression of DPP4 mRNA CTD PMID:24172598 NCBI chr 3:48,291,055...48,372,672
Ensembl chr 3:48,291,055...48,372,672
JBrowse link
G Dst dystonin decreases expression ISO 3,4-dichloroaniline results in decreased expression of DST mRNA CTD PMID:24172598 NCBI chr 9:37,902,336...38,296,961
Ensembl chr 9:37,902,303...38,196,273
JBrowse link
G Efemp1 EGF containing fibulin extracellular matrix protein 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of EFEMP1 mRNA CTD PMID:24172598 NCBI chr14:113,202,382...113,294,993
Ensembl chr14:113,202,419...113,295,014
JBrowse link
G Egr1 early growth response 1 decreases expression EXP 3,4-dichloroaniline results in decreased expression of EGR1 mRNA CTD PMID:24172598 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elovl6 ELOVL fatty acid elongase 6 decreases expression EXP 3,4-dichloroaniline results in decreased expression of ELOVL6 mRNA CTD PMID:24172598 NCBI chr 2:234,187,490...234,296,124
Ensembl chr 2:234,189,105...234,296,145
Ensembl chr 2:234,189,105...234,296,145
JBrowse link
G Eno2 enolase 2 increases expression ISO 3,4-dichloroaniline results in increased expression of ENO2 mRNA CTD PMID:24172598 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Entpd3 ectonucleoside triphosphate diphosphohydrolase 3 increases expression ISO 3,4-dichloroaniline results in increased expression of ENTPD3 mRNA CTD PMID:24172598 NCBI chr 8:129,201,000...129,232,436
Ensembl chr 8:129,201,669...129,232,677
JBrowse link
G Erp27 endoplasmic reticulum protein 27 decreases expression ISO 3,4-dichloroaniline results in decreased expression of ERP27 mRNA CTD PMID:24172598 NCBI chr 4:170,893,946...170,912,629
Ensembl chr 4:170,893,946...170,912,629
JBrowse link
G Fgfbp1 fibroblast growth factor binding protein 1 decreases expression EXP 3,4-dichloroaniline results in decreased expression of FGFBP1 mRNA CTD PMID:24172598 NCBI chr14:71,647,429...71,650,359
Ensembl chr14:71,649,274...71,650,354
JBrowse link
G Fkbp1b FKBP prolyl isomerase 1B decreases expression ISO 3,4-dichloroaniline results in decreased expression of FKBP1B mRNA CTD PMID:24172598 NCBI chr 6:29,975,863...29,987,252
Ensembl chr 6:29,977,797...29,987,451
JBrowse link
G Fstl1 follistatin-like 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of FSTL1 mRNA CTD PMID:24172598 NCBI chr11:65,791,196...65,845,721
Ensembl chr11:65,782,567...65,845,418
JBrowse link
G Fyb1 FYN binding protein 1 increases expression ISO 3,4-dichloroaniline results in increased expression of FYB1 mRNA CTD PMID:24172598 NCBI chr 2:55,834,904...55,983,805
Ensembl chr 2:55,835,151...55,983,804
JBrowse link
G Gask1b golgi associated kinase 1B decreases expression ISO 3,4-dichloroaniline results in decreased expression of GASK1B mRNA CTD PMID:24172598 NCBI chr 2:178,678,946...178,751,459
Ensembl chr 2:178,679,041...178,750,668
JBrowse link
G Gdf15 growth differentiation factor 15 increases expression EXP 3,4-dichloroaniline results in increased expression of GDF15 mRNA CTD PMID:24172598 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gjb6 gap junction protein, beta 6 decreases expression ISO 3,4-dichloroaniline results in decreased expression of GJB6 mRNA CTD PMID:24172598 NCBI chr15:37,400,888...37,411,656
Ensembl chr15:37,400,889...37,410,848
JBrowse link
G Has2 hyaluronan synthase 2 increases expression ISO 3,4-dichloroaniline results in increased expression of HAS2 mRNA CTD PMID:24172598 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression ISO 3,4-dichloroaniline results in increased expression of HPGD mRNA CTD PMID:24172598 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 increases expression ISO 3,4-dichloroaniline results in increased expression of HSD17B2 mRNA CTD PMID:24172598 NCBI chr19:50,246,404...50,317,892
Ensembl chr19:50,246,402...50,317,891
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 decreases expression EXP 3,4-dichloroaniline results in decreased expression of HSD17B7 mRNA CTD PMID:24172598 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Id3 inhibitor of DNA binding 3, HLH protein decreases expression ISO 3,4-dichloroaniline results in decreased expression of ID3 mRNA CTD PMID:24172598 NCBI chr 5:154,489,603...154,491,172
Ensembl chr 5:154,489,590...154,491,223
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression EXP 3,4-dichloroaniline results in decreased expression of IDI1 mRNA CTD PMID:24172598 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 increases expression EXP 3,4-dichloroaniline results in increased expression of IFITM3 mRNA CTD PMID:24172598 NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO 3,4-dichloroaniline results in increased expression of IGFBP3 mRNA CTD PMID:24172598 NCBI chr14:87,457,647...87,465,374
Ensembl chr14:87,457,647...87,465,374
JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 decreases expression EXP 3,4-dichloroaniline results in decreased expression of IGFBP6 mRNA CTD PMID:24172598 NCBI chr 7:143,749,385...143,754,018
Ensembl chr 7:143,749,221...143,754,054
JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO 3,4-dichloroaniline results in increased expression of IL1RL1 mRNA CTD PMID:24172598 NCBI chr 9:47,133,483...47,184,316
Ensembl chr 9:47,134,034...47,182,170
JBrowse link
G Il1rn interleukin 1 receptor antagonist increases expression ISO 3,4-dichloroaniline results in increased expression of IL1RN mRNA CTD PMID:24172598 NCBI chr 3:1,449,778...1,468,624
Ensembl chr 3:1,452,644...1,468,614
JBrowse link
G Itga1 integrin subunit alpha 1 increases expression EXP 3,4-dichloroaniline results in increased expression of ITGA1 mRNA CTD PMID:24172598 NCBI chr 2:47,127,403...47,281,387
Ensembl chr 2:47,127,219...47,281,421
JBrowse link
G Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KCNJ2 mRNA CTD PMID:24172598 NCBI chr10:99,429,337...99,442,520
Ensembl chr10:99,437,436...99,439,114
JBrowse link
G Kif20a kinesin family member 20A decreases expression ISO 3,4-dichloroaniline results in decreased expression of KIF20A mRNA CTD PMID:24172598 NCBI chr18:27,424,328...27,432,814
Ensembl chr18:27,424,328...27,432,814
JBrowse link
G Klhl13 kelch-like family member 13 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KLHL13 mRNA CTD PMID:24172598 NCBI chr  X:121,578,965...121,735,014
Ensembl chr  X:121,578,940...121,731,543
JBrowse link
G Klhl24 kelch-like family member 24 increases expression EXP 3,4-dichloroaniline results in increased expression of KLHL24 mRNA CTD PMID:24172598 NCBI chr11:84,613,101...84,643,674
Ensembl chr11:84,615,760...84,633,504
JBrowse link
G Klrc3 killer cell lectin like receptor C3 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KLRC3 mRNA CTD PMID:24172598 NCBI chr 4:163,416,373...163,427,331
Ensembl chr 4:163,416,351...163,445,302
JBrowse link
G Klrg2 killer cell lectin like receptor G2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of KLRG2 mRNA CTD PMID:24172598 NCBI chr 4:66,370,674...66,381,351
Ensembl chr 4:66,371,511...66,380,734
JBrowse link
G Krt34 keratin 34 increases expression ISO 3,4-dichloroaniline results in increased expression of KRT34 mRNA CTD PMID:24172598 NCBI chr10:87,950,364...87,954,055
Ensembl chr10:87,950,001...87,954,055
JBrowse link
G Lamb3 laminin subunit beta 3 increases expression ISO 3,4-dichloroaniline results in increased expression of LAMB3 mRNA CTD PMID:24172598 NCBI chr13:112,031,614...112,073,187
Ensembl chr13:112,031,594...112,073,186
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO
EXP
3,4-dichloroaniline results in increased expression of LCN2 mRNA CTD PMID:24172598 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G LOC100911204 protein CASC5-like decreases expression ISO 3,4-dichloroaniline results in decreased expression of KNL1 mRNA CTD PMID:24172598 NCBI chr 3:112,531,429...112,560,698
Ensembl chr 3:112,531,703...112,560,634
JBrowse link
G LOC103690190 histone H2A type 1-E increases expression ISO 3,4-dichloroaniline results in increased expression of H2AC6 mRNA CTD PMID:24172598 NCBI chr17:44,747,686...44,748,229
Ensembl chr17:44,747,796...44,748,188
Ensembl chr17:44,747,796...44,748,188
JBrowse link
G Maf MAF bZIP transcription factor increases expression ISO 3,4-dichloroaniline results in increased expression of MAF mRNA CTD PMID:24172598 NCBI chr19:48,179,826...48,200,995
Ensembl chr19:48,194,804...48,196,748
JBrowse link
G Matn3 matrilin 3 decreases expression ISO 3,4-dichloroaniline results in decreased expression of MATN3 mRNA CTD PMID:24172598 NCBI chr 6:34,071,428...34,091,048
Ensembl chr 6:34,071,428...34,091,048
JBrowse link
G Mctp1 multiple C2 and transmembrane domain containing 1 increases expression ISO 3,4-dichloroaniline results in increased expression of MCTP1 mRNA CTD PMID:24172598 NCBI chr 2:3,400,883...4,089,949
Ensembl chr 2:3,400,977...4,088,989
JBrowse link
G Mex3b mex-3 RNA binding family member B increases expression EXP 3,4-dichloroaniline results in increased expression of MEX3B mRNA CTD PMID:24172598 NCBI chr 1:144,831,523...144,835,758
Ensembl chr 1:144,831,523...144,835,747
JBrowse link
G Mical2 microtubule associated monooxygenase, calponin and LIM domain containing 2 increases expression ISO 3,4-dichloroaniline results in increased expression of MICAL2 mRNA CTD PMID:24172598 NCBI chr 1:177,048,607...177,173,729
Ensembl chr 1:177,048,655...177,173,995
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO 3,4-dichloroaniline results in increased expression of MMP1 mRNA CTD PMID:24172598 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO 3,4-dichloroaniline results in increased expression of MMP10 mRNA CTD PMID:24172598 NCBI chr 8:5,734,348...5,742,243
Ensembl chr 8:5,734,348...5,742,243
JBrowse link
G Mmp13 matrix metallopeptidase 13 increases expression EXP 3,4-dichloroaniline results in increased expression of MMP13 mRNA CTD PMID:24172598 NCBI chr 8:5,522,739...5,533,018
Ensembl chr 8:5,522,739...5,533,018
JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression EXP 3,4-dichloroaniline results in increased expression of MMP3 mRNA CTD PMID:24172598 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO [[MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 3,4-dichloroaniline] which results in increased expression of MPO protein modified form; [MPO protein co-treated with Hydrogen Peroxide co-treated with 5,5-dimethyl-1-pyrroline-1-oxide] results in increased metabolism of 3,4-dichloroaniline CTD PMID:20199096 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Msrb3 methionine sulfoxide reductase B3 decreases expression ISO 3,4-dichloroaniline results in decreased expression of MSRB3 mRNA CTD PMID:24172598 NCBI chr 7:62,850,506...62,972,487
Ensembl chr 7:62,850,515...62,972,084
JBrowse link
G Muc1 mucin 1, cell surface associated increases expression ISO 3,4-dichloroaniline results in increased expression of MUC1 mRNA CTD PMID:24172598 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Muc16 mucin 16, cell surface associated increases expression ISO 3,4-dichloroaniline results in increased expression of MUC16 mRNA CTD PMID:24172598 NCBI chr 8:18,438,838...18,639,777 JBrowse link
G Myo10 myosin X increases expression ISO 3,4-dichloroaniline results in increased expression of MYO10 mRNA CTD PMID:24172598 NCBI chr 2:77,868,398...78,072,443
Ensembl chr 2:77,868,412...78,071,309
JBrowse link
G Nat2 N-acetyltransferase 2 increases acetylation ISO NAT2 protein results in increased acetylation of 3,4-dichloroaniline CTD PMID:15627487 NCBI chr16:23,960,709...23,991,570
Ensembl chr16:23,961,067...23,991,570
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO 3,4-dichloroaniline results in increased expression of NDRG1 mRNA CTD PMID:24172598 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 decreases expression
increases expression
ISO
EXP
3,4-dichloroaniline results in decreased expression of NEDD9 mRNA
3,4-dichloroaniline results in increased expression of NEDD9 mRNA
CTD PMID:24172598 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Nt5e 5' nucleotidase, ecto increases expression ISO 3,4-dichloroaniline results in increased expression of NT5E mRNA CTD PMID:24172598 NCBI chr 8:95,969,002...96,012,733
Ensembl chr 8:95,968,652...96,012,696
JBrowse link
G Nusap1 nucleolar and spindle associated protein 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of NUSAP1 mRNA CTD PMID:24172598 NCBI chr 3:111,422,267...111,452,600
Ensembl chr 3:111,422,267...111,452,971
JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 increases expression ISO 3,4-dichloroaniline results in increased expression of OSTM1 mRNA CTD PMID:24172598 NCBI chr20:47,394,979...47,430,304
Ensembl chr20:47,395,014...47,430,284
JBrowse link
G Pappa1 pappalysin 1 increases expression ISO 3,4-dichloroaniline results in increased expression of PAPPA mRNA CTD PMID:24172598 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Pdk4 pyruvate dehydrogenase kinase 4 increases expression ISO 3,4-dichloroaniline results in increased expression of PDK4 mRNA CTD PMID:24172598 NCBI chr 4:30,546,772...30,556,774
Ensembl chr 4:30,546,664...30,556,814
JBrowse link
G Pgbd5 piggyBac transposable element derived 5 increases expression ISO 3,4-dichloroaniline results in increased expression of PGBD5 mRNA CTD PMID:24172598 NCBI chr19:57,126,110...57,192,182
Ensembl chr19:57,127,054...57,192,095
JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO 3,4-dichloroaniline results in increased expression of PLAUR mRNA CTD PMID:24172598 NCBI chr 1:81,328,171...81,344,954
Ensembl chr 1:81,328,183...81,344,708
JBrowse link
G Pld5 phospholipase D family, member 5 increases expression ISO 3,4-dichloroaniline results in increased expression of PLD5 mRNA CTD PMID:24172598 NCBI chr13:94,025,696...94,355,219
Ensembl chr13:94,025,369...94,355,219
JBrowse link
G Plk2 polo-like kinase 2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of PLK2 mRNA CTD PMID:24172598 NCBI chr 2:41,911,143...41,916,901
Ensembl chr 2:41,911,131...41,916,901
JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO 3,4-dichloroaniline results in increased expression of PRDM1 mRNA CTD PMID:24172598 NCBI chr20:49,464,921...49,556,623
Ensembl chr20:49,464,919...49,556,518
JBrowse link
G Prnp prion protein decreases expression ISO 3,4-dichloroaniline results in decreased expression of PRNP mRNA CTD PMID:24172598 NCBI chr 3:124,515,917...124,531,320
Ensembl chr 3:124,515,978...124,531,316
JBrowse link
G Prss23 serine protease 23 increases expression EXP 3,4-dichloroaniline results in increased expression of PRSS23 mRNA CTD PMID:24172598 NCBI chr 1:153,732,528...153,742,111
Ensembl chr 1:153,732,532...153,752,541
JBrowse link
G Ptger4 prostaglandin E receptor 4 decreases expression ISO 3,4-dichloroaniline results in decreased expression of PTGER4 mRNA CTD PMID:24172598 NCBI chr 2:54,951,625...54,966,470
Ensembl chr 2:54,952,821...54,963,448
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO 3,4-dichloroaniline results in increased expression of PTGS2 mRNA CTD PMID:24172598 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptprz1 protein tyrosine phosphatase, receptor type Z1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of PTPRZ1 mRNA CTD PMID:24172598 NCBI chr 4:49,941,046...50,140,764
Ensembl chr 4:49,941,304...50,140,762
JBrowse link
G Ralbp1 ralA binding protein 1 increases expression ISO 3,4-dichloroaniline results in increased expression of RALBP1 mRNA CTD PMID:24172598 NCBI chr 9:113,579,107...113,598,477
Ensembl chr 9:113,579,107...113,598,480
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO 3,4-dichloroaniline results in increased expression of RARRES1 mRNA CTD PMID:24172598 NCBI chr 2:164,650,722...164,684,982
Ensembl chr 2:164,650,722...164,684,985
JBrowse link
G Rbck1 RANBP2-type and C3HC4-type zinc finger containing 1 increases expression ISO 3,4-dichloroaniline results in increased expression of RBCK1 mRNA CTD PMID:24172598 NCBI chr 3:147,793,014...147,809,941
Ensembl chr 3:147,793,017...147,809,919
JBrowse link
G RGD1305347 similar to RIKEN cDNA 2610528J11 increases expression ISO 3,4-dichloroaniline results in increased expression of C1ORF210 mRNA CTD PMID:24172598 NCBI chr 5:137,356,777...137,360,636
Ensembl chr 5:137,356,801...137,360,580
JBrowse link
G Rnf128 ring finger protein 128 increases expression EXP 3,4-dichloroaniline results in increased expression of RNF128 mRNA CTD PMID:24172598 NCBI chr  X:110,789,061...110,877,964
Ensembl chr  X:110,789,269...110,877,978
JBrowse link
G Rora RAR-related orphan receptor A increases expression ISO 3,4-dichloroaniline results in increased expression of RORA mRNA CTD PMID:24172598 NCBI chr 8:75,515,886...75,616,477
Ensembl chr 8:75,516,904...75,607,212
JBrowse link
G Scd stearoyl-CoA desaturase increases expression ISO 3,4-dichloroaniline results in increased expression of SCD mRNA CTD PMID:24172598 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scg5 secretogranin V increases expression ISO 3,4-dichloroaniline results in increased expression of SCG5 mRNA CTD PMID:24172598 NCBI chr 3:105,235,065...105,279,475
Ensembl chr 3:105,235,050...105,279,462
JBrowse link
G Scrn1 secernin 1 decreases expression EXP 3,4-dichloroaniline results in decreased expression of SCRN1 mRNA CTD PMID:24172598 NCBI chr 4:84,678,978...84,740,701
Ensembl chr 4:84,678,975...84,740,909
JBrowse link
G Serpinb2 serpin family B member 2 increases expression
decreases expression
ISO
EXP
3,4-dichloroaniline results in increased expression of SERPINB2 mRNA
3,4-dichloroaniline results in decreased expression of SERPINB2 mRNA
CTD PMID:24172598 NCBI chr13:27,449,907...27,463,015
Ensembl chr13:27,449,934...27,463,010
JBrowse link
G Slc16a6 solute carrier family 16, member 6 increases expression ISO 3,4-dichloroaniline results in increased expression of SLC16A6 mRNA CTD PMID:24172598 NCBI chr10:97,733,701...97,758,723
Ensembl chr10:97,735,548...97,756,521
JBrowse link
G Slc1a6 solute carrier family 1 member 6 decreases expression ISO 3,4-dichloroaniline results in decreased expression of SLC1A6 mRNA CTD PMID:24172598 NCBI chr 7:13,730,101...13,758,170
Ensembl chr 7:13,730,253...13,751,271
JBrowse link
G Slco4a1 solute carrier organic anion transporter family, member 4a1 increases expression ISO 3,4-dichloroaniline results in increased expression of SLCO4A1 mRNA CTD PMID:24172598 NCBI chr 3:175,838,994...175,857,985
Ensembl chr 3:175,838,994...175,857,983
JBrowse link
G Smpd3 sphingomyelin phosphodiesterase 3 increases expression EXP 3,4-dichloroaniline results in increased expression of SMPD3 mRNA CTD PMID:24172598 NCBI chr19:38,237,963...38,321,572
Ensembl chr19:38,237,965...38,321,528
JBrowse link
G Sohlh2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 decreases expression ISO 3,4-dichloroaniline results in decreased expression of SOHLH2 mRNA CTD PMID:24172598 NCBI chr 2:144,591,755...144,614,065
Ensembl chr 2:144,591,755...144,614,064
JBrowse link
G Sowaha sosondowah ankyrin repeat domain family member A decreases expression ISO 3,4-dichloroaniline results in decreased expression of SOWAHA mRNA CTD PMID:24172598 NCBI chr10:38,836,158...38,838,932
Ensembl chr10:38,836,614...38,838,272
JBrowse link
G Spc24 SPC24 component of NDC80 kinetochore complex decreases expression ISO 3,4-dichloroaniline results in decreased expression of SPC24 mRNA CTD PMID:24172598 NCBI chr 8:22,780,639...22,785,908
Ensembl chr 8:22,780,725...22,785,671
JBrowse link
G St6gal1 ST6 beta-galactoside alpha-2,6-sialyltransferase 1 increases expression EXP 3,4-dichloroaniline results in increased expression of ST6GAL1 mRNA CTD PMID:24172598 NCBI chr11:80,927,601...80,981,424
Ensembl chr11:80,927,601...80,981,422
JBrowse link
G Sult1b1 sulfotransferase family 1B member 1 increases expression EXP 3,4-dichloroaniline results in increased expression of SULT1B1 mRNA CTD PMID:24172598 NCBI chr14:22,142,412...22,155,246
Ensembl chr14:22,142,364...22,155,231
JBrowse link
G Sun3 Sad1 and UNC84 domain containing 3 increases expression ISO 3,4-dichloroaniline results in increased expression of SUN3 mRNA CTD PMID:24172598 NCBI chr14:89,215,386...89,253,585
Ensembl chr14:89,215,703...89,238,094
JBrowse link
G Taf9b TATA-box binding protein associated factor 9b decreases expression ISO 3,4-dichloroaniline results in decreased expression of TAF9B mRNA CTD PMID:24172598 NCBI chr  X:77,281,234...77,295,238
Ensembl chr  X:77,281,210...77,295,426
JBrowse link
G Tent5b terminal nucleotidyltransferase 5B decreases expression ISO 3,4-dichloroaniline results in decreased expression of TENT5B mRNA CTD PMID:24172598 NCBI chr 5:151,692,068...151,699,381
Ensembl chr 5:151,692,108...151,700,246
JBrowse link
G Tgfbi transforming growth factor, beta induced decreases expression EXP 3,4-dichloroaniline results in decreased expression of TGFBI mRNA CTD PMID:24172598 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression ISO 3,4-dichloroaniline results in increased expression of TIMP1 mRNA CTD PMID:24172598 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 increases expression ISO 3,4-dichloroaniline results in increased expression of TMCC3 mRNA CTD PMID:24172598 NCBI chr 7:35,266,953...35,543,770
Ensembl chr 7:35,309,265...35,543,759
JBrowse link
G Tmem117 transmembrane protein 117 increases expression ISO 3,4-dichloroaniline results in increased expression of TMEM117 mRNA CTD PMID:24172598 NCBI chr 7:135,880,294...136,403,012
Ensembl chr 7:136,182,224...136,403,012
JBrowse link
G Tmem154 transmembrane protein 154 increases expression ISO 3,4-dichloroaniline results in increased expression of TMEM154 mRNA CTD PMID:24172598 NCBI chr 2:183,674,361...183,714,232
Ensembl chr 2:183,674,522...183,711,812
JBrowse link
G Tmem40 transmembrane protein 40 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TMEM40 mRNA CTD PMID:24172598 NCBI chr 4:147,645,333...147,657,847
Ensembl chr 4:147,645,333...147,657,847
JBrowse link
G Tnfaip8l1 TNF alpha induced protein 8 like 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TNFAIP8L1 mRNA CTD PMID:24172598 NCBI chr 9:10,894,949...10,905,647
Ensembl chr 9:10,896,680...10,897,240
JBrowse link
G Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 increases expression ISO 3,4-dichloroaniline results in increased expression of TNFRSF10D mRNA CTD PMID:24172598 NCBI chr 1:216,808,642...216,829,361
Ensembl chr 1:216,808,632...216,828,651
JBrowse link
G Tnfsf13b TNF superfamily member 13b increases expression ISO 3,4-dichloroaniline results in increased expression of TNFSF13B mRNA CTD PMID:24172598 NCBI chr16:85,275,690...85,306,419
Ensembl chr16:85,275,678...85,306,366
JBrowse link
G Tp63 tumor protein p63 decreases expression EXP 3,4-dichloroaniline results in decreased expression of TP63 mRNA CTD PMID:24172598 NCBI chr11:78,234,853...78,456,559
Ensembl chr11:78,234,800...78,456,501
JBrowse link
G Tprg1 tumor protein p63 regulated 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TPRG1 mRNA CTD PMID:24172598 NCBI chr11:78,733,046...78,861,745
Ensembl chr11:78,728,128...78,861,716
JBrowse link
G Trib3 tribbles pseudokinase 3 decreases expression EXP 3,4-dichloroaniline results in decreased expression of TRIB3 mRNA CTD PMID:24172598 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Trim59 tripartite motif-containing 59 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TRIM59 mRNA CTD PMID:24172598 NCBI chr 2:165,629,903...165,641,751
Ensembl chr 2:165,629,918...165,641,573
JBrowse link
G Trim6 tripartite motif containing 6 decreases expression ISO 3,4-dichloroaniline results in decreased expression of TRIM6 mRNA CTD PMID:24172598 NCBI chr 1:169,410,084...169,423,305
Ensembl chr 1:169,410,115...169,423,283
JBrowse link
G Ubd ubiquitin D increases expression EXP 3,4-dichloroaniline results in increased expression of UBD mRNA CTD PMID:24172598 NCBI chr20:1,876,175...1,878,126
Ensembl chr20:1,876,173...1,897,814
JBrowse link
G Vgll1 vestigial-like family member 1 decreases expression ISO 3,4-dichloroaniline results in decreased expression of VGLL1 mRNA CTD PMID:24172598 NCBI chr  X:159,556,296...159,576,639 JBrowse link
G Zbtb1 zinc finger and BTB domain containing 1 increases expression ISO 3,4-dichloroaniline results in increased expression of ZBTB1 mRNA CTD PMID:24172598 NCBI chr 6:99,401,775...99,425,739
Ensembl chr 6:99,402,360...99,424,019
JBrowse link
G Zc3h13 zinc finger CCCH type containing 13 decreases expression EXP 3,4-dichloroaniline results in decreased expression of ZC3H13 mRNA CTD PMID:24172598 NCBI chr15:57,340,522...57,405,287
Ensembl chr15:57,340,579...57,405,287
JBrowse link
propanil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor multiple interactions ISO Propanil binds to and results in increased activity of AHR protein CTD PMID:18835618 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Ar androgen receptor affects binding
multiple interactions
EXP
ISO
Propanil binds to AR protein
Dihydrotestosterone inhibits the reaction [Propanil results in increased activity of AR protein]
CTD PMID:14565775, PMID:15064155 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 increases expression ISO Propanil results in increased expression of DNAJB1 mRNA CTD PMID:24356939 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919
JBrowse link
G Hmgcs1 3-hydroxy-3-methylglutaryl-CoA synthase 1 decreases expression ISO Propanil results in decreased expression of HMGCS1 mRNA CTD PMID:24356939 NCBI chr 2:52,427,351...52,445,082
Ensembl chr 2:52,431,601...52,445,055
JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression ISO Propanil results in increased expression of HSPA1B mRNA CTD PMID:24356939 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO Propanil results in decreased expression of IDI1 mRNA CTD PMID:24356939 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Ifng interferon gamma multiple interactions ISO Lipopolysaccharides promotes the reaction [Propanil results in increased expression of IFNG mRNA]; Lipopolysaccharides promotes the reaction [Propanil results in increased expression of IFNG protein] CTD PMID:7679225 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Il2 interleukin 2 multiple interactions
decreases stability
ISO Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 mRNA]; Propanil inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of IL2 protein]
Propanil results in decreased stability of IL2 mRNA
CTD PMID:9925799 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases secretion
ISO Propanil promotes the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]
Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]
Propanil results in decreased secretion of IL6 protein
CTD PMID:9201266, PMID:9221836, PMID:17585980 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO Propanil inhibits the reaction [[NFKB1 protein binds to NFKB1 protein] which binds to TNF promoter]; Propanil inhibits the reaction [[RELA protein binds to NFKB1 protein] which binds to TNF promoter] CTD PMID:11312646 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:17355946 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Propanil inhibits the reaction [[RELA protein binds to NFKB1 protein] which binds to TNF promoter]; Propanil inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:11312646 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Sqle squalene epoxidase decreases expression ISO Propanil results in decreased expression of SQLE mRNA CTD PMID:24356939 NCBI chr 7:99,609,929...99,624,803
Ensembl chr 7:99,609,191...99,624,732
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression
decreases secretion
multiple interactions
ISO Propanil results in decreased expression of TNF protein
Propanil results in increased expression of TNF protein
Propanil results in decreased secretion of TNF protein
Lipopolysaccharides promotes the reaction [Propanil results in increased expression of TNF protein]; Propanil inhibits the reaction [[NFKB1 protein binds to NFKB1 protein] which binds to TNF promoter]; Propanil inhibits the reaction [[RELA protein binds to NFKB1 protein] which binds to TNF promoter]; Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Propanil inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
CTD PMID:7679225, PMID:9201266, PMID:9221836, PMID:11312646, PMID:17355946 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Zfp628 zinc finger protein 628 decreases expression ISO Propanil results in decreased expression of ZNF628 mRNA CTD PMID:24356939 NCBI chr 1:72,465,403...72,474,442
Ensembl chr 1:72,465,341...72,468,738
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        biochemical role 19304
          metabolite 19285
            1,2-dichlorobenzene 177
              3,4-dichloroaniline + 163
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic molecule 19514
                              organic cyclic compound 19311
                                carbocyclic compound 18219
                                  benzenoid aromatic compound 17254
                                    benzenes 17011
                                      chlorobenzenes 13348
                                        dichlorobenzene 10301
                                          1,2-dichlorobenzene 177
                                            3,4-dichloroaniline + 163
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.