L-proline betaine - Ontology Report

stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS4 protein]

NCBI chr 1:171,077,698...171,089,836
Ensembl chr 1:171,077,990...171,088,206

Adamts5

ADAM metallopeptidase with thrombospondin type 1 motif 5

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS5 protein]

NCBI chr16:85,655,045...85,698,013
Ensembl chr16:85,653,061...85,698,716

Il1b

interleukin 1 beta

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; stachydrine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]; stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS4 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of ADAMTS5 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]; stachydrine inhibits the reaction [IL1B protein results in increased secretion of TNF protein]

NCBI chr 2:129,206,490...129,213,059
Ensembl chr 2:129,206,490...129,213,059

Il6

interleukin 6

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased secretion of IL6 protein]

NCBI chr 5:30,218,112...30,224,973
Ensembl chr 5:30,218,112...30,224,979

Mmp13

matrix metallopeptidase 13

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP13 protein]

NCBI chr 9:7,272,514...7,283,333
Ensembl chr 9:7,272,514...7,283,331

Mmp3

matrix metallopeptidase 3

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased secretion of MMP3 protein]

NCBI chr 9:7,445,845...7,455,975
Ensembl chr 9:7,445,822...7,455,975

Nfkbia

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of NFKBIA protein]

NCBI chr12:55,536,194...55,539,432
Ensembl chr12:55,536,195...55,539,432

Nos2

nitric oxide synthase 2, inducible

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]

NCBI chr11:78,811,613...78,851,052
Ensembl chr11:78,811,613...78,851,080

Ptgs2

prostaglandin-endoperoxide synthase 2

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]

NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978

Rela

v-rel reticuloendotheliosis viral oncogene homolog A (avian)

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased phosphorylation of RELA protein]

NCBI chr19:5,686,993...5,698,162
Ensembl chr19:5,687,511...5,698,158

Tnf

tumor necrosis factor

multiple interactions

stachydrine inhibits the reaction [IL1B protein results in increased secretion of TNF protein]