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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoprene
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Accession:CHEBI:35194 term browser browse the term
Definition:A hemiterpene with the formula CH2=C(CH3)CH=CH2; the monomer of natural rubber and a common structure motif to the isoprenoids, a large class of other naturally occurring compounds.
Synonyms:related_synonym: 2-methyl-1,3-butadiene;   2-methylbuta-1,3-diene;   2-methylbutadiene;   2-methyldivinyl;   CH2=C(CH3)CH=CH2;   Formula=C5H8;   InChI=1S/C5H8/c1-4-5(2)3/h4H,1-2H2,3H3;   InChIKey=RRHGJUQNOFWUDK-UHFFFAOYSA-N;   Isopren;   SMILES=CC(=C)C=C;   beta-methylbivinyl;   isopentadiene;   isopreno;   isoterpene
 xref: Beilstein:969158;   CAS:78-79-5;   Gmelin:1768;   KEGG:C16521
 xref_mesh: MESH:C005059
 xref: MetaCyc:CPD-9436;   PMID:17921528;   PMID:19011917;   PMID:8690002;   Reaxys:969158;   Wikipedia:Isoprene


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isoprene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 increases expression ISO isoprene results in increased expression of CCND1 protein CTD PMID:30236600 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Ccne1 cyclin E1 increases expression ISO isoprene results in increased expression of CCNE1 protein CTD PMID:30236600 NCBI chr 1:94,485,830...94,495,112
Ensembl chr 1:94,485,832...94,494,980
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO isoprene results in decreased expression of CDH1 protein CTD PMID:30236600 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 increases expression ISO isoprene results in increased expression of CDH2 protein CTD PMID:30236600 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO isoprene results in decreased expression of CDKN1A protein CTD PMID:30236600 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO isoprene results in decreased expression of CDKN1B protein CTD PMID:30236600 NCBI chr 4:168,689,043...168,694,159
Ensembl chr 4:168,689,163...168,693,964
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis ISO isoprene results in increased mutagenesis of HRAS gene CTD PMID:9111215, PMID:11397402 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases mutagenesis ISO isoprene results in increased mutagenesis of KRAS gene CTD PMID:9111215, PMID:11397402 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO isoprene results in increased phosphorylation of MAPK1 protein CTD PMID:30236600 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO isoprene results in increased phosphorylation of MAPK3 protein CTD PMID:30236600 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mir125b1 microRNA 125b-1 decreases expression ISO isoprene analog results in decreased expression of MIR125B1 mRNA CTD PMID:31765140 NCBI chr 8:45,798,260...45,798,346
Ensembl chr 8:45,798,260...45,798,346
JBrowse link
G Mir141 microRNA 141 decreases expression ISO isoprene analog results in decreased expression of MIR141 mRNA CTD PMID:31765140 NCBI chr 4:157,236,346...157,236,439
Ensembl chr 4:157,236,346...157,236,439
JBrowse link
G Mir148b microRNA 148b decreases expression ISO isoprene analog results in decreased expression of MIR148B mRNA CTD PMID:31765140 NCBI chr 7:144,912,038...144,912,134
Ensembl chr 7:144,912,038...144,912,134
JBrowse link
G Mir19a microRNA 19a decreases expression ISO isoprene analog results in decreased expression of MIR19A mRNA CTD PMID:31765140 NCBI chr15:100,180,162...100,180,243
Ensembl chr15:100,180,162...100,180,243
JBrowse link
G Mir19b1 microRNA 19b-1 decreases expression ISO isoprene analog results in decreased expression of MIR19B-1 mRNA CTD PMID:31765140 NCBI chr15:100,180,464...100,180,550
Ensembl chr15:100,180,464...100,180,550
JBrowse link
G Mir20a microRNA 20a decreases expression ISO isoprene analog results in decreased expression of MIR20A mRNA CTD PMID:31765140 NCBI chr15:100,180,334...100,180,418
Ensembl chr15:100,180,334...100,180,418
JBrowse link
G Mir221 microRNA 221 decreases expression ISO isoprene analog results in decreased expression of MIR221 mRNA CTD PMID:31765140 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588
JBrowse link
G Mir27b microRNA 27b decreases expression ISO isoprene analog results in decreased expression of MIR27B mRNA CTD PMID:31765140 NCBI chr17:823,461...823,557
Ensembl chr17:823,461...823,557
JBrowse link
G Mir29a microRNA 29a decreases expression ISO isoprene analog results in decreased expression of MIR29A mRNA CTD PMID:31765140 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir30a microRNA 30a decreases expression ISO isoprene analog results in decreased expression of MIR30A mRNA CTD PMID:31765140 NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
JBrowse link
G Mir30c2 microRNA 30c-2 decreases expression ISO isoprene analog results in decreased expression of MIR30C2 mRNA CTD PMID:31765140 NCBI chr 9:29,562,376...29,562,459
Ensembl chr 9:29,562,376...29,562,459
JBrowse link
G Mir30e microRNA 30e decreases expression ISO isoprene analog results in decreased expression of MIR30E mRNA CTD PMID:31765140 NCBI chr 5:139,702,872...139,702,963
Ensembl chr 5:139,702,872...139,702,963
JBrowse link
G Mir322 microRNA 322 decreases expression ISO isoprene analog results in decreased expression of MIR424 mRNA CTD PMID:31765140 NCBI chr  X:158,148,161...158,148,255
Ensembl chr  X:158,148,161...158,148,255
JBrowse link
G Mir324 microRNA 324 decreases expression ISO isoprene analog results in decreased expression of MIR324 mRNA CTD PMID:31765140 NCBI chr10:56,621,126...56,621,208
Ensembl chr10:56,621,124...56,621,212
JBrowse link
G Mir423 microRNA 423 increases expression
decreases expression
ISO isoprene analog results in increased expression of MIR423 mRNA
isoprene analog results in decreased expression of MIR423 mRNA
CTD PMID:31765140 NCBI chr10:63,098,366...63,098,444
Ensembl chr10:63,098,360...63,098,453
JBrowse link
G Mir503 microRNA 503 decreases expression ISO isoprene analog results in decreased expression of MIR503 mRNA CTD PMID:31765140 NCBI chr  X:158,148,476...158,148,546
Ensembl chr  X:158,148,476...158,148,546
JBrowse link
G Mir93 microRNA 93 decreases expression ISO isoprene analog results in decreased expression of MIR93 mRNA CTD PMID:31765140 NCBI chr12:19,307,543...19,307,629
Ensembl chr12:19,307,543...19,307,629
JBrowse link
G Mirlet7c1 microRNA let-7c-1 decreases expression ISO isoprene analog results in decreased expression of MIRLET7C mRNA CTD PMID:31765140 NCBI chr11:16,052,873...16,052,966
Ensembl chr11:16,052,868...16,052,975
JBrowse link
G Mirlet7d microRNA let-7d decreases expression ISO isoprene analog results in decreased expression of MIRLET7D mRNA CTD PMID:31765140 NCBI chr17:16,419,980...16,420,077
Ensembl chr17:16,419,980...16,420,077
JBrowse link
G Ocln occludin decreases expression ISO isoprene results in decreased expression of OCLN protein CTD PMID:30236600 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO isoprene results in increased expression of SNAI2 protein CTD PMID:30236600 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      molecular entity 19784
        polyatomic entity 19697
          molecule 19520
            organic molecule 19488
              volatile organic compound 14387
                isoprene 31
                  4-[(E)-\{amino[(3-methylbut-2-en-1-yl)amino]methylidene\}amino]butanoic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    main group molecular entity 19672
                      s-block molecular entity 19430
                        hydrogen molecular entity 19420
                          hydrides 18686
                            organic hydride 18249
                              organic fundamental parent 18249
                                hydrocarbon 17969
                                  olefin 7183
                                    acyclic olefin 7164
                                      alkadiene 2076
                                        isoprene 31
                                          4-[(E)-\{amino[(3-methylbut-2-en-1-yl)amino]methylidene\}amino]butanoic acid 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.