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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:isoprene
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Accession:CHEBI:35194 term browser browse the term
Definition:A hemiterpene with the formula CH2=C(CH3)CH=CH2; the monomer of natural rubber and a common structure motif to the isoprenoids, a large class of other naturally occurring compounds.
Synonyms:exact_synonym: 2-methylbuta-1,3-diene
 related_synonym: 2-methyl-1,3-butadiene;   2-methylbutadiene;   2-methyldivinyl;   CH2=C(CH3)CH=CH2;   Formula=C5H8;   InChI=1S/C5H8/c1-4-5(2)3/h4H,1-2H2,3H3;   InChIKey=RRHGJUQNOFWUDK-UHFFFAOYSA-N;   Isopren;   SMILES=CC(=C)C=C;   beta-methylbivinyl;   isopentadiene;   isopreno;   isoterpene
 xref: Beilstein:969158;   CAS:78-79-5;   Gmelin:1768;   KEGG:C16521
 xref_mesh: MESH:C005059
 xref: MetaCyc:CPD-9436;   PMID:17921528;   PMID:19011917;   PMID:8690002;   Reaxys:969158;   Wikipedia:Isoprene



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isoprene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnd1 cyclin D1 increases expression ISO isoprene results in increased expression of CCND1 protein CTD PMID:30236600 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 increases expression ISO isoprene results in increased expression of CCNE1 protein CTD PMID:30236600 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdh1 cadherin 1 decreases expression ISO isoprene results in decreased expression of CDH1 protein CTD PMID:30236600 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdh2 cadherin 2 increases expression ISO isoprene results in increased expression of CDH2 protein CTD PMID:30236600 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO isoprene results in decreased expression of CDKN1A protein CTD PMID:30236600 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO isoprene results in decreased expression of CDKN1B protein CTD PMID:30236600 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
JBrowse link
G Hras HRas proto-oncogene, GTPase increases mutagenesis ISO isoprene results in increased mutagenesis of HRAS gene CTD PMID:9111215 PMID:11397402 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
JBrowse link
G Kras KRAS proto-oncogene, GTPase increases mutagenesis ISO isoprene results in increased mutagenesis of KRAS gene CTD PMID:9111215 PMID:11397402 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation ISO isoprene results in increased phosphorylation of MAPK1 protein CTD PMID:30236600 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation ISO isoprene results in increased phosphorylation of MAPK3 protein CTD PMID:30236600 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mir125b1 microRNA 125b-1 decreases expression ISO isoprene analog results in decreased expression of MIR125B1 mRNA CTD PMID:31765140 NCBI chr 8:41,952,966...41,953,052
Ensembl chr 8:41,952,966...41,953,052
JBrowse link
G Mir141 microRNA 141 decreases expression ISO isoprene analog results in decreased expression of MIR141 mRNA CTD PMID:31765140 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
JBrowse link
G Mir148b microRNA 148b decreases expression ISO isoprene analog results in decreased expression of MIR148B mRNA CTD PMID:31765140 NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494
JBrowse link
G Mir19a microRNA 19a decreases expression ISO isoprene analog results in decreased expression of MIR19A mRNA CTD PMID:31765140 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir19b1 microRNA 19b-1 decreases expression ISO isoprene analog results in decreased expression of MIR19B-1 mRNA CTD PMID:31765140 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300
JBrowse link
G Mir20a microRNA 20a decreases expression ISO isoprene analog results in decreased expression of MIR20A mRNA CTD PMID:31765140 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir221 microRNA 221 decreases expression ISO isoprene analog results in decreased expression of MIR221 mRNA CTD PMID:31765140 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir27b microRNA 27b decreases expression ISO isoprene analog results in decreased expression of MIR27B mRNA CTD PMID:31765140 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mir29a microRNA 29a decreases expression ISO isoprene analog results in decreased expression of MIR29A mRNA CTD PMID:31765140 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir30a microRNA 30a decreases expression ISO isoprene analog results in decreased expression of MIR30A mRNA CTD PMID:31765140 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mir30c2 microRNA 30c-2 decreases expression ISO isoprene analog results in decreased expression of MIR30C2 mRNA CTD PMID:31765140 NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
JBrowse link
G Mir30e microRNA 30e decreases expression ISO isoprene analog results in decreased expression of MIR30E mRNA CTD PMID:31765140 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
JBrowse link
G Mir322 microRNA 322 decreases expression ISO isoprene analog results in decreased expression of MIR424 mRNA CTD PMID:31765140 NCBI chr  X:132,806,594...132,806,688 JBrowse link
G Mir324 microRNA 324 decreases expression ISO isoprene analog results in decreased expression of MIR324 mRNA CTD PMID:31765140 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766
JBrowse link
G Mir423 microRNA 423 increases expression
decreases expression
ISO isoprene analog results in increased expression of MIR423 mRNA
isoprene analog results in decreased expression of MIR423 mRNA
CTD PMID:31765140 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir503 microRNA 503 decreases expression ISO isoprene analog results in decreased expression of MIR503 mRNA CTD PMID:31765140 NCBI chr  X:132,806,303...132,806,373 JBrowse link
G Mir93 microRNA 93 decreases expression ISO isoprene analog results in decreased expression of MIR93 mRNA CTD PMID:31765140 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Mirlet7c1 microRNA let-7c-1 decreases expression ISO isoprene analog results in decreased expression of MIRLET7C mRNA CTD PMID:31765140 NCBI chr11:16,201,163...16,201,256
Ensembl chr11:16,201,158...16,201,265
JBrowse link
G Mirlet7d microRNA let-7d decreases expression ISO isoprene analog results in decreased expression of MIRLET7D mRNA CTD PMID:31765140 NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990
JBrowse link
G Ocln occludin decreases expression ISO isoprene results in decreased expression of OCLN protein CTD PMID:30236600 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression ISO isoprene results in increased expression of SNAI2 protein CTD PMID:30236600 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19795
    chemical entity 19795
      molecular entity 19794
        polyatomic entity 19716
          molecule 19568
            organic molecule 19545
              volatile organic compound 14507
                isoprene 31
                  4-[(E)-\{amino[(3-methylbut-2-en-1-yl)amino]methylidene\}amino]butanoic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19795
    subatomic particle 19794
      composite particle 19794
        hadron 19794
          baryon 19794
            nucleon 19794
              atomic nucleus 19794
                atom 19794
                  main group element atom 19693
                    main group molecular entity 19693
                      s-block molecular entity 19474
                        hydrogen molecular entity 19466
                          hydrides 18830
                            organic hydride 18346
                              organic fundamental parent 18346
                                hydrocarbon 18057
                                  olefin 5477
                                    acyclic olefin 5449
                                      alkadiene 2081
                                        isoprene 31
                                          4-[(E)-\{amino[(3-methylbut-2-en-1-yl)amino]methylidene\}amino]butanoic acid 0
paths to the root