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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tetraterpene
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Accession:CHEBI:35193 term browser browse the term
Definition:A C40 terpene.
Synonyms:related_synonym: tetraterpenes;   tetraterpeno;   tetraterpenos



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8'-apo-beta,psi-caroten-8'-al term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACADM acyl-CoA dehydrogenase medium chain increases expression EXP apocarotenal results in increased expression of ACADM mRNA CTD PMID:17034753 NCBI chr 1:75,724,709...75,763,679
Ensembl chr 1:75,724,431...75,787,575
JBrowse link
G ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide increases expression EXP apocarotenal results in increased expression of ADH1A mRNA CTD PMID:17034753 NCBI chr 4:99,276,369...99,290,985
Ensembl chr 4:99,276,369...99,291,003
JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression EXP apocarotenal results in increased expression of ADH5 mRNA CTD PMID:17034753 NCBI chr 4:99,070,978...99,088,788
Ensembl chr 4:99,070,978...99,088,801
JBrowse link
G ALDH1B1 aldehyde dehydrogenase 1 family member B1 decreases expression EXP apocarotenal results in decreased expression of ALDH1B1 mRNA CTD PMID:17034753 NCBI chr 9:38,392,702...38,398,661
Ensembl chr 9:38,392,702...38,398,661
JBrowse link
G ALDH3B1 aldehyde dehydrogenase 3 family member B1 decreases expression EXP apocarotenal results in decreased expression of ALDH3B1 mRNA CTD PMID:17034753 NCBI chr11:68,008,547...68,029,276
Ensembl chr11:68,008,578...68,029,282
JBrowse link
G ALDH4A1 aldehyde dehydrogenase 4 family member A1 decreases expression EXP apocarotenal results in decreased expression of ALDH4A1 mRNA CTD PMID:17034753 NCBI chr 1:18,871,430...18,902,555
Ensembl chr 1:18,871,430...18,902,724
JBrowse link
G ANK2 ankyrin 2 increases expression EXP apocarotenal results in increased expression of ANK2 mRNA CTD PMID:17034753 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G ANK3 ankyrin 3 increases expression EXP apocarotenal results in increased expression of ANK3 mRNA CTD PMID:17034753 NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490
JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 increases expression EXP apocarotenal results in increased expression of ASAH1 mRNA CTD PMID:17034753 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998
JBrowse link
G ASB1 ankyrin repeat and SOCS box containing 1 increases expression EXP apocarotenal results in increased expression of ASB1 mRNA CTD PMID:17034753 NCBI chr 2:238,426,927...238,452,250
Ensembl chr 2:238,426,742...238,452,250
JBrowse link
G ASB9 ankyrin repeat and SOCS box containing 9 increases expression EXP apocarotenal results in increased expression of ASB9 mRNA CTD PMID:17034753 NCBI chr  X:15,243,987...15,270,467
Ensembl chr  X:15,235,288...15,270,467
JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression EXP apocarotenal results in decreased expression of BAX mRNA CTD PMID:17034753 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCO2 beta-carotene oxygenase 2 multiple interactions ISO [BCO2 protein results in increased metabolism of beta Carotene] which results in increased chemical synthesis of apocarotenal; [BCO2 protein results in increased metabolism of Cryptoxanthins] which results in increased chemical synthesis of apocarotenal; [BCO2 protein results in increased metabolism of Lutein] which results in increased chemical synthesis of apocarotenal metabolite; [BCO2 protein results in increased metabolism of Zeaxanthins] which results in increased chemical synthesis of apocarotenal metabolite CTD PMID:21106934 NCBI chr11:112,175,512...112,218,946
Ensembl chr11:112,175,510...112,224,699
JBrowse link
G CASP8AP2 caspase 8 associated protein 2 increases expression EXP apocarotenal results in increased expression of CASP8AP2 mRNA CTD PMID:17034753 NCBI chr 6:89,829,880...89,874,436
Ensembl chr 6:89,829,894...89,874,436
JBrowse link
G CDH1 cadherin 1 increases expression EXP apocarotenal results in increased expression of CDH1 mRNA CTD PMID:17034753 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CLDN10 claudin 10 increases expression EXP apocarotenal results in increased expression of CLDN10 mRNA CTD PMID:17034753 NCBI chr13:95,433,755...95,579,759
Ensembl chr13:95,433,604...95,579,759
JBrowse link
G CLDN18 claudin 18 increases expression EXP apocarotenal results in increased expression of CLDN18 mRNA CTD PMID:17034753 NCBI chr 3:137,998,816...138,033,649
Ensembl chr 3:137,998,735...138,033,655
JBrowse link
G COL1A1 collagen type I alpha 1 chain decreases expression EXP apocarotenal results in decreased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL4A1 collagen type IV alpha 1 chain decreases expression EXP apocarotenal results in decreased expression of COL4A1 mRNA CTD PMID:17034753 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,157
JBrowse link
G COL4A2 collagen type IV alpha 2 chain decreases expression EXP apocarotenal results in decreased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209
JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 decreases expression EXP apocarotenal results in decreased expression of CRABP2 mRNA CTD PMID:17034753 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
JBrowse link
G CTSB cathepsin B decreases expression EXP apocarotenal results in decreased expression of CTSB mRNA CTD PMID:17034753 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 increases expression EXP apocarotenal results in increased expression of CXCL12 mRNA CTD PMID:17034753 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 increases expression EXP apocarotenal results in increased expression of CXCL6 mRNA CTD PMID:17034753 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 increases expression EXP apocarotenal results in increased expression of CXCL9 mRNA CTD PMID:17034753 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 increases expression EXP apocarotenal results in increased expression of CXCR4 mRNA CTD PMID:17034753 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 increases expression EXP apocarotenal results in increased expression of CYP2C9 mRNA CTD PMID:17034753 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G DLX2 distal-less homeobox 2 increases expression EXP apocarotenal results in increased expression of DLX2 mRNA CTD PMID:17034753 NCBI chr 2:172,099,438...172,102,900
Ensembl chr 2:172,099,438...172,102,900
JBrowse link
G DLX4 distal-less homeobox 4 increases expression EXP apocarotenal results in increased expression of DLX4 mRNA CTD PMID:17034753 NCBI chr17:49,968,572...49,974,959
Ensembl chr17:49,968,970...49,974,959
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression EXP apocarotenal results in decreased expression of ERCC2 mRNA CTD PMID:17034753 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ETS1 ETS proto-oncogene 1, transcription factor decreases expression EXP apocarotenal results in decreased expression of ETS1 mRNA CTD PMID:17034753 NCBI chr11:128,458,765...128,587,558
Ensembl chr11:128,458,761...128,587,558
JBrowse link
G FAS Fas cell surface death receptor increases expression EXP apocarotenal results in increased expression of FAS mRNA CTD PMID:17034753 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FASN fatty acid synthase decreases expression EXP apocarotenal results in decreased expression of FASN mRNA CTD PMID:17034753 NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G GATA6 GATA binding protein 6 increases expression EXP apocarotenal results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G GBP1 guanylate binding protein 1 increases expression EXP apocarotenal results in increased expression of GBP1 mRNA CTD PMID:17034753 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360
JBrowse link
G GJA9 gap junction protein alpha 9 increases expression EXP apocarotenal results in increased expression of GJA9 mRNA CTD PMID:17034753 NCBI chr 1:38,874,069...38,881,587
Ensembl chr 1:38,874,069...38,881,587
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 decreases expression EXP apocarotenal results in decreased expression of GSTK1 mRNA CTD PMID:17034753 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
JBrowse link
G GSTM2 glutathione S-transferase mu 2 decreases expression EXP apocarotenal results in decreased expression of GSTM2 mRNA CTD PMID:17034753 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTM4 glutathione S-transferase mu 4 decreases expression EXP apocarotenal results in decreased expression of GSTM4 mRNA CTD PMID:17034753 NCBI chr 1:109,656,099...109,667,727
Ensembl chr 1:109,656,099...109,674,836
JBrowse link
G GSTM5 glutathione S-transferase mu 5 increases expression EXP apocarotenal results in increased expression of GSTM5 mRNA CTD PMID:17034753 NCBI chr 1:109,711,751...109,718,268
Ensembl chr 1:109,711,780...109,775,428
JBrowse link
G GSTZ1 glutathione S-transferase zeta 1 decreases expression EXP apocarotenal results in decreased expression of GSTZ1 mRNA CTD PMID:17034753 NCBI chr14:77,321,036...77,331,597
Ensembl chr14:77,320,996...77,331,597
JBrowse link
G HOXA7 homeobox A7 increases expression EXP apocarotenal results in increased expression of HOXA7 mRNA CTD PMID:17034753 NCBI chr 7:27,153,716...27,156,675
Ensembl chr 7:27,153,716...27,157,936
JBrowse link
G HOXB6 homeobox B6 increases expression EXP apocarotenal results in increased expression of HOXB6 mRNA CTD PMID:17034753 NCBI chr17:48,595,751...48,604,986
Ensembl chr17:48,595,751...48,604,992
JBrowse link
G HOXC10 homeobox C10 increases expression EXP apocarotenal results in increased expression of HOXC10 mRNA CTD PMID:17034753 NCBI chr12:53,985,146...53,990,279
Ensembl chr12:53,985,065...53,990,279
JBrowse link
G IFNA14 interferon alpha 14 increases expression EXP apocarotenal results in increased expression of IFNA14 mRNA CTD PMID:17034753 NCBI chr 9:21,239,002...21,240,005
Ensembl chr 9:21,239,002...21,240,005
JBrowse link
G IFNA16 interferon alpha 16 increases expression EXP apocarotenal results in increased expression of IFNA16 mRNA CTD PMID:17034753 NCBI chr 9:21,216,373...21,217,311
Ensembl chr 9:21,216,373...21,217,311
JBrowse link
G IFNA17 interferon alpha 17 increases expression EXP apocarotenal results in increased expression of IFNA17 mRNA CTD PMID:17034753 NCBI chr 9:21,227,243...21,228,222
Ensembl chr 9:21,227,243...21,228,222
JBrowse link
G IFNA5 interferon alpha 5 increases expression EXP apocarotenal results in increased expression of IFNA5 mRNA CTD PMID:17034753 NCBI chr 9:21,304,326...21,305,313
Ensembl chr 9:21,304,326...21,305,313
JBrowse link
G IRF8 interferon regulatory factor 8 increases expression EXP apocarotenal results in increased expression of IRF8 mRNA CTD PMID:17034753 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606
JBrowse link
G IRX4 iroquois homeobox 4 decreases expression EXP apocarotenal results in decreased expression of IRX4 mRNA CTD PMID:17034753 NCBI chr 5:1,877,413...1,887,179
Ensembl chr 5:1,877,413...1,887,236
JBrowse link
G ITGB4 integrin subunit beta 4 decreases expression EXP apocarotenal results in decreased expression of ITGB4 mRNA CTD PMID:17034753 NCBI chr17:75,721,459...75,757,818
Ensembl chr17:75,721,328...75,757,818
JBrowse link
G IVL involucrin increases expression EXP apocarotenal results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
JBrowse link
G KRT17 keratin 17 decreases expression EXP apocarotenal results in decreased expression of KRT17 mRNA CTD PMID:17034753 NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842
JBrowse link
G KRT2 keratin 2 increases expression EXP apocarotenal results in increased expression of KRT2 mRNA CTD PMID:17034753 NCBI chr12:52,644,558...52,652,211
Ensembl chr12:52,644,558...52,652,211
JBrowse link
G KRT7 keratin 7 affects expression EXP apocarotenal affects the expression of KRT7 mRNA CTD PMID:17034753 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186
JBrowse link
G LHX3 LIM homeobox 3 increases expression EXP apocarotenal results in increased expression of LHX3 mRNA CTD PMID:17034753 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member affects expression EXP apocarotenal affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738
JBrowse link
G MEIS2 Meis homeobox 2 increases expression EXP apocarotenal results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr15:36,889,204...37,101,311
Ensembl chr15:36,889,204...37,101,299
JBrowse link
G MEOX1 mesenchyme homeobox 1 increases expression EXP apocarotenal results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr17:43,640,389...43,661,922
Ensembl chr17:43,640,389...43,661,922
JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 increases expression EXP apocarotenal results in increased expression of MNX1 mRNA CTD PMID:17034753 NCBI chr 7:157,004,854...157,010,663
Ensembl chr 7:156,994,051...157,010,663
JBrowse link
G MSH5 mutS homolog 5 increases expression EXP apocarotenal results in increased expression of MSH5 mRNA CTD PMID:17034753 NCBI chr 6:31,740,005...31,762,676
Ensembl chr 6:31,739,677...31,762,676
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming increases expression EXP apocarotenal results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G NOS1 nitric oxide synthase 1 increases expression EXP apocarotenal results in increased expression of NOS1 mRNA CTD PMID:17034753 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 increases expression EXP apocarotenal results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138
JBrowse link
G PCDHGC3 protocadherin gamma subfamily C, 3 increases expression EXP apocarotenal results in increased expression of PCDHGC3 mRNA CTD PMID:17034753 NCBI chr 5:141,475,966...141,512,975
Ensembl chr 5:141,475,947...141,512,977
JBrowse link
G PLAAT4 phospholipase A and acyltransferase 4 decreases expression EXP apocarotenal results in decreased expression of PLAAT4 mRNA CTD PMID:17034753 NCBI chr11:63,536,808...63,546,458
Ensembl chr11:63,536,808...63,546,462
JBrowse link
G PLSCR1 phospholipid scramblase 1 increases expression EXP apocarotenal results in increased expression of PLSCR1 mRNA CTD PMID:17034753 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856
JBrowse link
G PLSCR3 phospholipid scramblase 3 increases expression EXP apocarotenal results in increased expression of PLSCR3 mRNA CTD PMID:17034753 NCBI chr17:7,389,727...7,394,525
Ensembl chr17:7,389,727...7,394,842
JBrowse link
G PLSCR4 phospholipid scramblase 4 increases expression EXP apocarotenal results in increased expression of PLSCR4 mRNA CTD PMID:17034753 NCBI chr 3:146,192,335...146,251,105
Ensembl chr 3:146,192,335...146,251,179
JBrowse link
G RAD51AP1 RAD51 associated protein 1 increases expression EXP apocarotenal results in increased expression of RAD51AP1 mRNA CTD PMID:17034753 NCBI chr12:4,538,890...4,560,047
Ensembl chr12:4,538,798...4,560,047
JBrowse link
G RAD51D RAD51 paralog D increases expression EXP apocarotenal results in increased expression of RAD51D mRNA CTD PMID:17034753 NCBI chr17:35,092,221...35,119,860
Ensembl chr17:35,092,221...35,121,522
JBrowse link
G RARA retinoic acid receptor alpha decreases expression EXP apocarotenal results in decreased expression of RARA mRNA CTD PMID:17034753 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
JBrowse link
G RARB retinoic acid receptor beta increases expression EXP apocarotenal results in increased expression of RARB mRNA CTD PMID:17034753 NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932
JBrowse link
G RARRES1 retinoic acid receptor responder 1 increases expression EXP apocarotenal results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 3:158,696,892...158,732,457
Ensembl chr 3:158,696,892...158,732,489
JBrowse link
G SIX6 SIX homeobox 6 increases expression EXP apocarotenal results in increased expression of SIX6 mRNA CTD PMID:17034753 NCBI chr14:60,509,146...60,512,850
Ensembl chr14:60,509,146...60,512,850
JBrowse link
G SOD1 superoxide dismutase 1 decreases expression EXP apocarotenal results in decreased expression of SOD1 mRNA CTD PMID:17034753 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 affects expression EXP apocarotenal affects the expression of SPTLC2 mRNA CTD PMID:17034753 NCBI chr14:77,505,997...77,616,637
Ensembl chr14:77,505,997...77,616,637
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression EXP apocarotenal results in increased expression of SREBF1 mRNA CTD PMID:17034753 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G TGM4 transglutaminase 4 increases expression EXP apocarotenal results in increased expression of TGM4 mRNA CTD PMID:17034753 NCBI chr 3:44,874,608...44,914,990
Ensembl chr 3:44,874,608...44,914,990
JBrowse link
G TNFRSF9 TNF receptor superfamily member 9 increases expression EXP apocarotenal results in increased expression of TNFRSF9 mRNA CTD PMID:17034753 NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165
JBrowse link
G TNFSF10 TNF superfamily member 10 increases expression EXP apocarotenal results in increased expression of TNFSF10 mRNA CTD PMID:17034753 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
JBrowse link
G TXNDC9 thioredoxin domain containing 9 increases expression EXP apocarotenal results in increased expression of TXNDC9 mRNA CTD PMID:17034753 NCBI chr 2:99,306,184...99,336,333
Ensembl chr 2:99,318,982...99,340,702
JBrowse link
G XRCC3 X-ray repair cross complementing 3 increases expression EXP apocarotenal results in increased expression of XRCC3 mRNA CTD PMID:17034753 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504
JBrowse link
9'-cis-neoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 affects localization EXP neoxanthin affects the localization of AIFM1 protein CTD PMID:17186379 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G CASP3 caspase 3 multiple interactions EXP neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17186379 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 increases activity EXP neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 multiple interactions EXP neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:17186379 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
all-trans-neoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 affects localization EXP neoxanthin affects the localization of AIFM1 protein CTD PMID:17186379 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G CASP3 caspase 3 multiple interactions EXP neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17186379 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 increases activity EXP neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 multiple interactions EXP neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:17186379 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
all-trans-phytoene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESR1 estrogen receptor 1 multiple interactions EXP [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions EXP [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
JBrowse link
all-trans-phytofluene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ESR1 estrogen receptor 1 multiple interactions EXP [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions EXP [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
JBrowse link
alpha-carotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MGMT O-6-methylguanine-DNA methyltransferase affects response to substance EXP MGMT gene SNP affects the susceptibility to alpha-carotene CTD PMID:16014702 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
astaxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AIFM1 apoptosis inducing factor mitochondria associated 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA] CTD PMID:16964424 NCBI chr  X:130,129,362...130,165,841
Ensembl chr  X:130,124,666...130,165,879
JBrowse link
G APP amyloid beta precursor protein multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA] CTD PMID:16964424 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ATG12 autophagy related 12 multiple interactions EXP astaxanthine inhibits the reaction [bisphenol A results in increased expression of ATG12 mRNA] CTD PMID:34439521 NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837
JBrowse link
G ATG14 autophagy related 14 multiple interactions EXP astaxanthine inhibits the reaction [bisphenol A results in increased expression of ATG14 mRNA] CTD PMID:34439521 NCBI chr14:55,366,391...55,411,830
Ensembl chr14:55,366,391...55,411,830
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions EXP astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] CTD PMID:33212048 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BECN1 beclin 1 multiple interactions EXP astaxanthine inhibits the reaction [bisphenol A results in increased expression of BECN1 mRNA]; astaxanthine inhibits the reaction [bisphenol A results in increased expression of BECN1 protein] CTD PMID:34439521 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G C1QA complement C1q A chain decreases expression ISO astaxanthine results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678
JBrowse link
G CASP3 caspase 3 multiple interactions EXP astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA] CTD PMID:33212048 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CAT catalase multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CAT mRNA] CTD PMID:16964424 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CNTD1 cyclin N-terminal domain containing 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CNTD1 mRNA] CTD PMID:16964424 NCBI chr17:42,798,785...42,811,587
Ensembl chr17:42,798,800...42,811,587
JBrowse link
G COX15 cytochrome c oxidase assembly homolog COX15 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX15 mRNA] CTD PMID:16964424 NCBI chr10:99,694,293...99,732,127
Ensembl chr10:99,710,868...99,732,127
JBrowse link
G COX5A cytochrome c oxidase subunit 5A multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5A mRNA] CTD PMID:16964424 NCBI chr15:74,919,791...74,938,073
Ensembl chr15:74,919,791...74,938,083
JBrowse link
G COX5B cytochrome c oxidase subunit 5B multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5B mRNA] CTD PMID:16964424 NCBI chr 2:97,646,062...97,648,383
Ensembl chr 2:97,646,062...97,648,383
JBrowse link
G COX6B1 cytochrome c oxidase subunit 6B1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA] CTD PMID:16964424 NCBI chr19:35,648,323...35,658,782
Ensembl chr19:35,648,323...35,658,782
JBrowse link
G COX6C cytochrome c oxidase subunit 6C multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6C mRNA] CTD PMID:16964424 NCBI chr 8:99,877,865...99,893,707
Ensembl chr 8:99,873,200...99,893,707
JBrowse link
G CTSS cathepsin S decreases expression ISO astaxanthine results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
JBrowse link
G CYBB cytochrome b-245 beta chain multiple interactions
decreases expression
ISO astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]]
astaxanthine results in decreased expression of CYBB mRNA
CTD PMID:23272707 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 multiple interactions
increases expression
ISO astaxanthine results in increased expression of and results in increased activity of CYP1A1 protein
astaxanthine results in increased expression of CYP1A1 mRNA
CTD PMID:21414371 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G FOXO3 forkhead box O3 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of FOXO3 mRNA] CTD PMID:16964424 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G G6PD glucose-6-phosphate dehydrogenase increases activity
multiple interactions
ISO astaxanthine results in increased activity of G6PD protein
[Cadmium co-treated with astaxanthine] results in decreased activity of G6PD protein
CTD PMID:28665548 PMID:29975440 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572
JBrowse link
G GFAP glial fibrillary acidic protein decreases expression ISO astaxanthine results in decreased expression of GFAP mRNA CTD PMID:19555370 NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
JBrowse link
G GJA1 gap junction protein alpha 1 increases expression
multiple interactions
ISO astaxanthine results in increased expression of GJA1 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [astaxanthine results in increased expression of GJA1 protein]; astaxanthine promotes the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of GJA1 protein]
CTD PMID:16091010 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GNA13 G protein subunit alpha 13 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA] CTD PMID:16964424 NCBI chr17:65,009,289...65,056,740
Ensembl chr17:65,009,289...65,056,740
JBrowse link
G GPX3 glutathione peroxidase 3 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GPX3 mRNA] CTD PMID:16964424 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions ISO [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]] CTD PMID:23538867 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,139,154...137,168,756
JBrowse link
G GRN granulin precursor multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GRN mRNA] CTD PMID:16964424 NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO astaxanthine inhibits the reaction [Cadmium results in decreased activity of GSR protein] CTD PMID:29975440 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTM2 glutathione S-transferase mu 2 multiple interactions
increases expression
EXP [astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of GSTM2 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of GSTM2 mRNA
astaxanthine results in increased expression of GSTM2 mRNA
CTD PMID:24157545 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G HMGB1 high mobility group box 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HMGB1 mRNA] CTD PMID:16964424 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597
JBrowse link
G HMOX1 heme oxygenase 1 increases expression
decreases expression
multiple interactions
ISO
EXP
astaxanthine results in increased expression of HMOX1 protein
astaxanthine results in decreased expression of HMOX1 mRNA
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of HMOX1 protein; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]]
astaxanthine results in increased expression of HMOX1 mRNA
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of HMOX1 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of HMOX1 mRNA; astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]
CTD PMID:20038455 PMID:23272707 PMID:24157545 PMID:33212048 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HOXA9 homeobox A9 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HOXA9 mRNA] CTD PMID:16964424 NCBI chr 7:27,162,438...27,165,537
Ensembl chr 7:27,162,438...27,175,180
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA] CTD PMID:16964424 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IFNG interferon gamma increases expression ISO astaxanthine results in increased expression of IFNG protein CTD PMID:33132140 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
JBrowse link
G IL11 interleukin 11 increases expression ISO astaxanthine results in increased expression of IL11 protein CTD PMID:33132140 NCBI chr19:55,364,382...55,370,463
Ensembl chr19:55,364,382...55,370,463
JBrowse link
G IL1B interleukin 1 beta decreases expression ISO astaxanthine results in decreased expression of IL1B mRNA; astaxanthine results in decreased expression of IL1B protein CTD PMID:21621527 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 decreases expression ISO astaxanthine results in decreased expression of IL6 mRNA CTD PMID:21621527 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G LEPR leptin receptor multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CAT mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CNTD1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX15 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5A mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5B mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6C mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of FOXO3 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GPX3 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GRN mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HMGB1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HOXA9 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA5 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFC2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFV2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NME2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PPP1CB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PRDX1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of RPS2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SOD1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UBB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRC2 mRNA] CTD PMID:16964424 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559
JBrowse link
G MAP1LC3B2 microtubule associated protein 1 light chain 3 beta 2 multiple interactions EXP astaxanthine inhibits the reaction [bisphenol A results in increased expression of MAP1LC3B2 mRNA] CTD PMID:34439521 NCBI chr12:116,559,381...116,576,606
Ensembl chr12:116,548,105...116,576,606
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions EXP astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein] CTD PMID:34439521 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions EXP astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein] CTD PMID:34439521 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MT-ND6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA] CTD PMID:16964424 NCBI chr MT:14,149...14,673
Ensembl chr MT:14,149...14,673
JBrowse link
G NDUFA1 NADH:ubiquinone oxidoreductase subunit A1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA1 mRNA] CTD PMID:16964424 NCBI chr  X:119,871,832...119,876,662
Ensembl chr  X:119,871,832...119,876,662
JBrowse link
G NDUFA5 NADH:ubiquinone oxidoreductase subunit A5 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA5 mRNA] CTD PMID:16964424 NCBI chr 7:123,536,997...123,601,651
Ensembl chr 7:123,536,997...123,557,904
JBrowse link
G NDUFC2 NADH:ubiquinone oxidoreductase subunit C2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFC2 mRNA] CTD PMID:16964424 NCBI chr11:78,068,297...78,079,862
Ensembl chr11:78,068,297...78,079,862
JBrowse link
G NDUFV2 NADH:ubiquinone oxidoreductase core subunit V2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFV2 mRNA] CTD PMID:16964424 NCBI chr18:9,102,699...9,134,341
Ensembl chr18:9,102,630...9,134,345
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
ISO
EXP
astaxanthine results in increased expression of NFE2L2 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NFE2L2 protein; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 protein]]
astaxanthine results in increased expression of NFE2L2 mRNA
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of NFE2L2 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of NFE2L2 mRNA; astaxanthine promotes the reaction [Hydrogen Peroxide results in increased expression of NFE2L2 mRNA]
CTD PMID:20038455 PMID:23272707 PMID:24157545 PMID:33212048 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NME2 NME/NM23 nucleoside diphosphate kinase 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NME2 mRNA] CTD PMID:16964424 NCBI chr17:51,165,536...51,171,744
Ensembl chr17:51,165,435...51,171,744
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO
EXP
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NQO1 protein
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of NQO1 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of NQO1 mRNA; astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of NQO1 mRNA]
astaxanthine results in increased expression of NQO1 mRNA
astaxanthine results in increased expression of NQO1 protein
CTD PMID:20038455 PMID:24157545 PMID:33212048 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G PAH phenylalanine hydroxylase decreases expression ISO astaxanthine results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410
JBrowse link
G PGD phosphogluconate dehydrogenase increases activity ISO astaxanthine results in increased activity of PGD protein CTD PMID:28665548 PMID:29975440 NCBI chr 1:10,399,064...10,420,511
Ensembl chr 1:10,398,592...10,420,511
JBrowse link
G POR cytochrome p450 oxidoreductase decreases activity
increases expression
ISO astaxanthine results in decreased activity of POR protein
astaxanthine results in increased expression of POR protein
CTD PMID:21414371 NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855
JBrowse link
G PPP1CB protein phosphatase 1 catalytic subunit beta multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PPP1CB mRNA] CTD PMID:16964424 NCBI chr 2:28,751,604...28,802,940
Ensembl chr 2:28,751,640...28,802,940
JBrowse link
G PRDX1 peroxiredoxin 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PRDX1 mRNA] CTD PMID:16964424 NCBI chr 1:45,511,051...45,522,890
Ensembl chr 1:45,510,914...45,542,732
JBrowse link
G PTEN phosphatase and tensin homolog multiple interactions EXP astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of PTEN mRNA] CTD PMID:33212048 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression ISO astaxanthine results in decreased expression of PTGS2 mRNA CTD PMID:21621527 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP astaxanthine inhibits the reaction [bisphenol A results in increased phosphorylation of RELA protein] CTD PMID:34439521 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RPS2 ribosomal protein S2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of RPS2 mRNA] CTD PMID:16964424 NCBI chr16:1,962,058...1,964,826
Ensembl chr16:1,962,058...1,964,841
JBrowse link
G SKAP2 src kinase associated phosphoprotein 2 decreases expression ISO astaxanthine results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 7:26,654,770...26,864,590
Ensembl chr 7:26,667,068...26,995,239
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SOD1 mRNA] CTD PMID:16964424 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SP1 Sp1 transcription factor multiple interactions ISO [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of and affects the localization of SP1 protein]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]] CTD PMID:23538867 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
JBrowse link
G SPP1 secreted phosphoprotein 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA] CTD PMID:16964424 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532
JBrowse link
G TGM2 transglutaminase 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA] CTD PMID:16964424 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578
JBrowse link
G TKT transketolase multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA] CTD PMID:16964424 NCBI chr 3:53,224,712...53,256,022
Ensembl chr 3:53,224,712...53,256,052
JBrowse link
G TNF tumor necrosis factor decreases expression
increases expression
ISO astaxanthine results in decreased expression of TNF protein
astaxanthine results in increased expression of TNF protein
CTD PMID:21621527 PMID:33132140 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TP53 tumor protein p53 multiple interactions ISO astaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein] CTD PMID:20038455 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G UBB ubiquitin B multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UBB mRNA] CTD PMID:16964424 NCBI chr17:16,380,779...16,382,745
Ensembl chr17:16,380,798...16,382,745
JBrowse link
G UQCRB ubiquinol-cytochrome c reductase binding protein multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRB mRNA] CTD PMID:16964424 NCBI chr 8:96,222,947...96,235,545
Ensembl chr 8:96,222,947...96,235,546
JBrowse link
G UQCRC2 ubiquinol-cytochrome c reductase core protein 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRC2 mRNA] CTD PMID:16964424 NCBI chr16:21,953,361...21,983,660
Ensembl chr16:21,953,288...21,983,660
JBrowse link
beta-carotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAD9 acyl-CoA dehydrogenase family member 9 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ACAD9 mRNA CTD PMID:24657404 NCBI chr 3:128,879,620...128,913,114
Ensembl chr 3:128,879,596...128,924,003
JBrowse link
G ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide increases expression EXP beta Carotene results in increased expression of ADH1A mRNA CTD PMID:17034753 NCBI chr 4:99,276,369...99,290,985
Ensembl chr 4:99,276,369...99,291,003
JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression EXP beta Carotene results in increased expression of ADH5 mRNA CTD PMID:17034753 NCBI chr 4:99,070,978...99,088,788
Ensembl chr 4:99,070,978...99,088,801
JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing decreases expression ISO beta Carotene results in decreased expression of ADIPOQ mRNA CTD PMID:21569430 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
JBrowse link
G AEBP1 AE binding protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of AEBP1 mRNA CTD PMID:24657404 NCBI chr 7:44,104,345...44,114,560
Ensembl chr 7:44,104,345...44,114,562
JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation EXP beta Carotene results in decreased phosphorylation of AKT1 protein CTD PMID:26733226 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions ISO beta Carotene inhibits the reaction [arsenic trioxide results in decreased expression of ALAD protein] CTD PMID:25542264 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G ALDH3B1 aldehyde dehydrogenase 3 family member B1 decreases expression EXP beta Carotene results in decreased expression of ALDH3B1 mRNA CTD PMID:17034753 NCBI chr11:68,008,547...68,029,276
Ensembl chr11:68,008,578...68,029,282
JBrowse link
G ALDH4A1 aldehyde dehydrogenase 4 family member A1 decreases expression EXP beta Carotene results in decreased expression of ALDH4A1 mRNA CTD PMID:17034753 NCBI chr 1:18,871,430...18,902,555
Ensembl chr 1:18,871,430...18,902,724
JBrowse link
G ANK2 ankyrin 2 increases expression EXP beta Carotene results in increased expression of ANK2 mRNA CTD PMID:17034753 NCBI chr 4:112,705,622...113,383,736
Ensembl chr 4:112,818,032...113,384,221
JBrowse link
G ANK3 ankyrin 3 increases expression EXP beta Carotene results in increased expression of ANK3 mRNA CTD PMID:17034753 NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490
JBrowse link
G APPBP2 amyloid beta precursor protein binding protein 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of APPBP2 mRNA CTD PMID:24657404 NCBI chr17:60,443,158...60,526,242
Ensembl chr17:60,443,158...60,526,242
JBrowse link
G ARHGAP26 Rho GTPase activating protein 26 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ARHGAP26 mRNA CTD PMID:24657404 NCBI chr 5:142,770,377...143,229,011
Ensembl chr 5:142,770,377...143,229,011
JBrowse link
G ASAH1 N-acylsphingosine amidohydrolase 1 increases expression EXP beta Carotene results in increased expression of ASAH1 mRNA CTD PMID:17034753 NCBI chr 8:18,055,992...18,084,961
Ensembl chr 8:18,055,992...18,084,998
JBrowse link
G ASB1 ankyrin repeat and SOCS box containing 1 increases expression EXP beta Carotene results in increased expression of ASB1 mRNA CTD PMID:17034753 NCBI chr 2:238,426,927...238,452,250
Ensembl chr 2:238,426,742...238,452,250
JBrowse link
G ASB9 ankyrin repeat and SOCS box containing 9 increases expression EXP beta Carotene results in increased expression of ASB9 mRNA CTD PMID:17034753 NCBI chr  X:15,243,987...15,270,467
Ensembl chr  X:15,235,288...15,270,467
JBrowse link
G ATP8B1 ATPase phospholipid transporting 8B1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ATP8B1 mRNA CTD PMID:24657404 NCBI chr18:57,646,426...57,803,315
Ensembl chr18:57,646,426...57,803,315
JBrowse link
G BAG3 BAG cochaperone 3 decreases expression EXP beta Carotene results in decreased expression of BAG3 mRNA CTD PMID:17034753 NCBI chr10:119,651,380...119,677,819
Ensembl chr10:119,651,380...119,677,819
JBrowse link
G BAG4 BAG cochaperone 4 decreases expression EXP beta Carotene results in decreased expression of BAG4 mRNA CTD PMID:17034753 NCBI chr 8:38,176,855...38,213,301
Ensembl chr 8:38,176,533...38,213,301
JBrowse link
G BAG5 BAG cochaperone 5 decreases expression EXP beta Carotene results in decreased expression of BAG5 mRNA CTD PMID:17034753 NCBI chr14:103,556,551...103,562,657
Ensembl chr14:103,556,545...103,562,657
JBrowse link
G BAX BCL2 associated X, apoptosis regulator decreases expression
increases expression
EXP beta Carotene results in decreased expression of BAX mRNA
beta Carotene results in increased expression of BAX mRNA; beta Carotene results in increased expression of BAX protein
CTD PMID:15949688 PMID:17034753 PMID:26733226 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP beta Carotene results in decreased expression of BCL2 protein CTD PMID:26733226 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCO1 beta-carotene oxygenase 1 multiple interactions
affects response to substance
increases oxidation
increases expression
EXP
ISO
beta Carotene results in increased expression of and results in increased activity of BCO1 protein
[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ACAD9 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of AEBP1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of APPBP2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ARHGAP26 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ATP8B1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CDCA8 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CENPE mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CLCN3 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of COQ7 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CTNNAL1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DTWD2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FOXM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FZD6 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of IRX4 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ITM2A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of KIF11 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LMNB2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL21A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL9 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MRPL57 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MTCH2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NCKAP1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NOM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PARD6A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PCDH1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PLAT mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RPP14 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RRM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TFCP2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of THOC7 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TMEM209 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TTC21B mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TWF1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TYMP mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of YTHDC2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ZDHHC3 mRNA
BCO1 protein results in increased oxidation of beta Carotene
beta Carotene results in increased expression of BCO1 mRNA
Ascorbic Acid inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]; Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]; Vitamin E inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]
CTD PMID:9526112 PMID:16186334 PMID:24657404 NCBI chr16:81,238,689...81,291,142
Ensembl chr16:81,238,689...81,291,142
JBrowse link
G BCO2 beta-carotene oxygenase 2 multiple interactions
increases metabolic processing
ISO [BCO2 protein results in increased metabolism of beta Carotene] which results in increased chemical synthesis of apocarotenal CTD PMID:21106934 NCBI chr11:112,175,512...112,218,946
Ensembl chr11:112,175,510...112,224,699
JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity
EXP alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]
beta Carotene metabolite results in increased activity of CASP3 protein; beta Carotene results in increased activity of CASP3 protein
CTD PMID:17618090 PMID:26733226 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CAT catalase multiple interactions ISO [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; beta Carotene inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; beta Carotene inhibits the reaction [Indomethacin results in decreased expression of CAT protein]
beta Carotene inhibits the reaction [arsenic trioxide results in decreased activity of CAT protein]
CTD PMID:9306888 PMID:12500499 PMID:25542264 PMID:31022331 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CAV1 caveolin 1 decreases expression EXP beta Carotene results in decreased expression of CAV1 protein CTD PMID:26733226 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
JBrowse link
G CCND1 cyclin D1 decreases expression EXP beta Carotene results in decreased expression of CCND1 protein CTD PMID:26733226 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CDCA8 cell division cycle associated 8 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CDCA8 mRNA CTD PMID:24657404 NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719
JBrowse link
G CDH1 cadherin 1 increases expression EXP beta Carotene results in increased expression of CDH1 mRNA; beta Carotene results in increased expression of CDH1 protein CTD PMID:17034753 PMID:26733226 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha decreases expression ISO beta Carotene results in decreased expression of CEBPA mRNA CTD PMID:21569430 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CENPE centromere protein E multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CENPE mRNA CTD PMID:24657404 NCBI chr 4:103,105,811...103,198,343
Ensembl chr 4:103,105,349...103,198,445
JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator increases expression EXP beta Carotene results in increased expression of CFLAR mRNA CTD PMID:17034753 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687
JBrowse link
G CLCN3 chloride voltage-gated channel 3 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CLCN3 mRNA CTD PMID:24657404 NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673
JBrowse link
G CLDN10 claudin 10 increases expression EXP beta Carotene results in increased expression of CLDN10 mRNA CTD PMID:17034753 NCBI chr13:95,433,755...95,579,759
Ensembl chr13:95,433,604...95,579,759
JBrowse link
G CLDN18 claudin 18 increases expression EXP beta Carotene results in increased expression of CLDN18 mRNA CTD PMID:17034753 NCBI chr 3:137,998,816...138,033,649
Ensembl chr 3:137,998,735...138,033,655
JBrowse link
G COL1A1 collagen type I alpha 1 chain decreases expression EXP beta Carotene results in decreased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632
JBrowse link
G COL4A1 collagen type IV alpha 1 chain decreases expression EXP beta Carotene results in decreased expression of COL4A1 mRNA CTD PMID:17034753 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,157
JBrowse link
G COL4A2 collagen type IV alpha 2 chain decreases expression EXP beta Carotene results in decreased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209
JBrowse link
G COQ7 coenzyme Q7, hydroxylase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of COQ7 mRNA CTD PMID:24657404 NCBI chr16:19,067,614...19,083,097
Ensembl chr16:19,067,614...19,080,095
JBrowse link
G CPT1B carnitine palmitoyltransferase 1B decreases expression ISO beta Carotene results in decreased expression of CPT1B mRNA CTD PMID:21569430 NCBI chr22:50,568,861...50,578,612
Ensembl chr22:50,568,861...50,578,465
JBrowse link
G CRADD CASP2 and RIPK1 domain containing adaptor with death domain increases expression EXP beta Carotene results in increased expression of CRADD mRNA CTD PMID:17034753 NCBI chr12:93,677,375...93,894,840
Ensembl chr12:93,677,375...93,894,840
JBrowse link
G CTNNAL1 catenin alpha like 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CTNNAL1 mRNA CTD PMID:24657404 NCBI chr 9:108,942,577...109,013,499
Ensembl chr 9:108,942,569...109,013,522
JBrowse link
G CTSB cathepsin B decreases expression EXP beta Carotene results in decreased expression of CTSB mRNA CTD PMID:17034753 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 increases expression EXP beta Carotene results in increased expression of CXCL12 mRNA CTD PMID:17034753 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
JBrowse link
G CXCL6 C-X-C motif chemokine ligand 6 increases expression EXP beta Carotene results in increased expression of CXCL6 mRNA CTD PMID:17034753 NCBI chr 4:73,836,678...73,838,760
Ensembl chr 4:73,836,640...73,849,064
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP beta Carotene promotes the reaction [Tetradecanoylphorbol Acetate results in increased secretion of CXCL8 protein] CTD PMID:19135038 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CXCL9 C-X-C motif chemokine ligand 9 increases expression EXP beta Carotene results in increased expression of CXCL9 mRNA CTD PMID:17034753 NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509
JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 increases expression EXP beta Carotene results in increased expression of CXCR4 mRNA CTD PMID:17034753 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 multiple interactions EXP beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]] CTD PMID:16970932 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G CYP26A1 cytochrome P450 family 26 subfamily A member 1 increases expression EXP beta Carotene results in increased expression of CYP26A1 mRNA CTD PMID:16186334 PMID:22542753 NCBI chr10:93,073,475...93,077,885
Ensembl chr10:93,073,475...93,077,885
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 increases expression EXP beta Carotene results in increased expression of CYP2C9 mRNA CTD PMID:17034753 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 multiple interactions EXP beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
JBrowse link
G CYP3A43 cytochrome P450 family 3 subfamily A member 43 increases expression EXP beta Carotene results in increased expression of CYP3A43 mRNA CTD PMID:17034753 NCBI chr 7:99,828,013...99,866,093
Ensembl chr 7:99,828,013...99,866,093
JBrowse link
G DHFR dihydrofolate reductase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA CTD PMID:24657404 NCBI chr 5:80,626,226...80,654,983
Ensembl chr 5:80,626,226...80,654,983
JBrowse link
G DLX2 distal-less homeobox 2 increases expression EXP beta Carotene results in increased expression of DLX2 mRNA CTD PMID:17034753 NCBI chr 2:172,099,438...172,102,900
Ensembl chr 2:172,099,438...172,102,900
JBrowse link
G DLX4 distal-less homeobox 4 increases expression EXP beta Carotene results in increased expression of DLX4 mRNA CTD PMID:17034753 NCBI chr17:49,968,572...49,974,959
Ensembl chr17:49,968,970...49,974,959
JBrowse link
G DPP4 dipeptidyl peptidase 4 multiple interactions ISO [Xiao-Ke-An results in increased abundance of beta Carotene] which results in decreased activity of DPP4 protein CTD PMID:32535096 NCBI chr 2:161,992,245...162,074,215
Ensembl chr 2:161,992,245...162,074,394
JBrowse link
G DTWD2 DTW domain containing 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DTWD2 mRNA CTD PMID:24657404 NCBI chr 5:118,836,074...118,988,547
Ensembl chr 5:118,836,074...118,988,547
JBrowse link
G EDN1 endothelin 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA CTD PMID:24657404 NCBI chr 6:12,256,484...12,297,194
Ensembl chr 6:12,290,361...12,297,194
JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA CTD PMID:24657404 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression EXP beta Carotene results in decreased expression of ERCC2 mRNA CTD PMID:17034753 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ESR1 estrogen receptor 1 multiple interactions EXP beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; beta Carotene inhibits the reaction [Genistein results in increased activity of ESR1 protein]; beta Carotene inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] CTD PMID:17051425 PMID:19340624 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 multiple interactions EXP beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]; beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G FABP4 fatty acid binding protein 4 decreases expression ISO beta Carotene results in decreased expression of FABP4 mRNA CTD PMID:21569430 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236
JBrowse link
G FAIM2 Fas apoptotic inhibitory molecule 2 increases expression EXP beta Carotene results in increased expression of FAIM2 mRNA CTD PMID:17034753 NCBI chr12:49,866,896...49,903,900
Ensembl chr12:49,866,896...49,904,217
JBrowse link
G FAS Fas cell surface death receptor increases expression EXP beta Carotene results in increased expression of FAS mRNA CTD PMID:17034753 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
JBrowse link
G FOSL1 FOS like 1, AP-1 transcription factor subunit increases expression ISO beta Carotene results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
JBrowse link
G FOXA1 forkhead box A1 increases expression EXP beta Carotene results in increased expression of FOXA1 mRNA CTD PMID:17034753 NCBI chr14:37,589,552...37,595,249
Ensembl chr14:37,589,552...37,596,059
JBrowse link
G FOXM1 forkhead box M1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FOXM1 mRNA CTD PMID:24657404 NCBI chr12:2,857,680...2,877,174
Ensembl chr12:2,857,680...2,877,174
JBrowse link
G FZD6 frizzled class receptor 6 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FZD6 mRNA CTD PMID:24657404 NCBI chr 8:103,298,494...103,332,866
Ensembl chr 8:103,298,433...103,332,866
JBrowse link
G GATA6 GATA binding protein 6 increases expression EXP beta Carotene results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528
JBrowse link
G GBP1 guanylate binding protein 1 increases expression EXP beta Carotene results in increased expression of GBP1 mRNA CTD PMID:17034753 NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360
JBrowse link
G GJA1 gap junction protein alpha 1 multiple interactions
increases expression
ISO beta Carotene promotes the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of GJA1 protein]; Ro 41-5253 inhibits the reaction [beta Carotene results in increased expression of GJA1 protein]
beta Carotene inhibits the reaction [Hydrogen Peroxide results in decreased expression of GJA1 mRNA]; beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GJA1 protein]
CTD PMID:16091010 PMID:27154496 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJA9 gap junction protein alpha 9 increases expression EXP beta Carotene results in increased expression of GJA9 mRNA CTD PMID:17034753 NCBI chr 1:38,874,069...38,881,587
Ensembl chr 1:38,874,069...38,881,587
JBrowse link
G GSR glutathione-disulfide reductase multiple interactions ISO beta Carotene inhibits the reaction [arsenic trioxide results in decreased activity of GSR protein] CTD PMID:25542264 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 decreases expression EXP beta Carotene results in decreased expression of GSTK1 mRNA CTD PMID:17034753 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
JBrowse link
G GSTM2 glutathione S-transferase mu 2 increases expression EXP beta Carotene results in increased expression of GSTM2 mRNA CTD PMID:17034753 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551
JBrowse link
G GSTM4 glutathione S-transferase mu 4 decreases expression EXP beta Carotene results in decreased expression of GSTM4 mRNA CTD PMID:17034753 NCBI chr 1:109,656,099...109,667,727
Ensembl chr 1:109,656,099...109,674,836
JBrowse link
G GSTM5 glutathione S-transferase mu 5 increases expression EXP beta Carotene results in increased expression of GSTM5 mRNA CTD PMID:17034753 NCBI chr 1:109,711,751...109,718,268
Ensembl chr 1:109,711,780...109,775,428
JBrowse link
G GSTZ1 glutathione S-transferase zeta 1 decreases expression EXP beta Carotene results in decreased expression of GSTZ1 mRNA CTD PMID:17034753 NCBI chr14:77,321,036...77,331,597
Ensembl chr14:77,320,996...77,331,597
JBrowse link
G HOXA7 homeobox A7 increases expression EXP beta Carotene results in increased expression of HOXA7 mRNA CTD PMID:17034753 NCBI chr 7:27,153,716...27,156,675
Ensembl chr 7:27,153,716...27,157,936
JBrowse link
G HOXB6 homeobox B6 increases expression EXP beta Carotene results in increased expression of HOXB6 mRNA CTD PMID:17034753 NCBI chr17:48,595,751...48,604,986
Ensembl chr17:48,595,751...48,604,992
JBrowse link
G HOXC10 homeobox C10 increases expression EXP beta Carotene results in increased expression of HOXC10 mRNA CTD PMID:17034753 NCBI chr12:53,985,146...53,990,279
Ensembl chr12:53,985,065...53,990,279
JBrowse link
G HPRT1 hypoxanthine phosphoribosyltransferase 1 multiple interactions ISO beta Carotene inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 NCBI chr  X:134,460,165...134,500,668
Ensembl chr  X:134,460,165...134,520,513
JBrowse link
G IFNA14 interferon alpha 14 increases expression EXP beta Carotene results in increased expression of IFNA14 mRNA CTD PMID:17034753 NCBI chr 9:21,239,002...21,240,005
Ensembl chr 9:21,239,002...21,240,005
JBrowse link
G IFNA16 interferon alpha 16 increases expression EXP beta Carotene results in increased expression of IFNA16 mRNA CTD PMID:17034753 NCBI chr 9:21,216,373...21,217,311
Ensembl chr 9:21,216,373...21,217,311
JBrowse link
G IFNA17 interferon alpha 17 increases expression EXP beta Carotene results in increased expression of IFNA17 mRNA CTD PMID:17034753 NCBI chr 9:21,227,243...21,228,222
Ensembl chr 9:21,227,243...21,228,222
JBrowse link
G IFNA5 interferon alpha 5 increases expression EXP beta Carotene results in increased expression of IFNA5 mRNA CTD PMID:17034753 NCBI chr 9:21,304,326...21,305,313
Ensembl chr 9:21,304,326...21,305,313
JBrowse link
G IGFBP5 insulin like growth factor binding protein 5 multiple interactions ISO [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA CTD PMID:23859036 NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
JBrowse link
G IL1B interleukin 1 beta multiple interactions EXP beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]; pyrazolanthrone inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]] CTD PMID:21447443 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IRF8 interferon regulatory factor 8 increases expression EXP beta Carotene results in increased expression of IRF8 mRNA CTD PMID:17034753 NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606
JBrowse link
G IRX4 iroquois homeobox 4 decreases expression
multiple interactions
EXP
ISO
beta Carotene results in decreased expression of IRX4 mRNA
[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of IRX4 mRNA
CTD PMID:17034753 PMID:24657404 NCBI chr 5:1,877,413...1,887,179
Ensembl chr 5:1,877,413...1,887,236
JBrowse link
G ITGB1 integrin subunit beta 1 decreases expression EXP beta Carotene results in decreased expression of ITGB1 mRNA CTD PMID:17034753 NCBI chr10:32,900,318...32,958,230
Ensembl chr10:32,887,273...33,005,792
JBrowse link
G ITGB4 integrin subunit beta 4 decreases expression EXP beta Carotene results in decreased expression of ITGB4 mRNA CTD PMID:17034753 NCBI chr17:75,721,459...75,757,818
Ensembl chr17:75,721,328...75,757,818
JBrowse link
G ITM2A integral membrane protein 2A multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ITM2A mRNA CTD PMID:24657404 NCBI chr  X:79,360,384...79,367,334
Ensembl chr  X:79,360,384...79,367,667
JBrowse link
G IVL involucrin increases expression EXP beta Carotene results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 1:152,908,546...152,911,886
Ensembl chr 1:152,908,546...152,911,886
JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO beta Carotene results in increased expression of JUN protein CTD PMID:20025956 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
JBrowse link
G KIF11 kinesin family member 11 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of KIF11 mRNA CTD PMID:24657404 NCBI chr10:92,593,130...92,655,395
Ensembl chr10:92,574,105...92,655,395
JBrowse link
G KRT18 keratin 18 increases expression EXP beta Carotene results in increased expression of KRT18 mRNA CTD PMID:17034753 NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906
JBrowse link
G KRT19 keratin 19 increases expression EXP beta Carotene results in increased expression of KRT19 mRNA CTD PMID:17034753 NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308
JBrowse link
G KRT2 keratin 2 increases expression EXP beta Carotene results in increased expression of KRT2 mRNA CTD PMID:17034753 NCBI chr12:52,644,558...52,652,211
Ensembl chr12:52,644,558...52,652,211
JBrowse link
G KRT7 keratin 7 affects expression EXP beta Carotene affects the expression of KRT7 mRNA CTD PMID:17034753 NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186
JBrowse link
G KRT8 keratin 8 decreases expression EXP beta Carotene results in decreased expression of KRT8 mRNA CTD PMID:17034753 NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954
JBrowse link
G LANCL1 LanC like glutathione S-transferase 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA CTD PMID:24657404 NCBI chr 2:210,431,251...210,477,584
Ensembl chr 2:210,431,249...210,477,652
JBrowse link
G LHX3 LIM homeobox 3 increases expression EXP beta Carotene results in increased expression of LHX3 mRNA CTD PMID:17034753 NCBI chr 9:136,196,250...136,205,128
Ensembl chr 9:136,196,250...136,205,128
JBrowse link
G LMNB2 lamin B2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LMNB2 mRNA CTD PMID:24657404 NCBI chr19:2,428,166...2,456,959
Ensembl chr19:2,427,638...2,456,959
JBrowse link
G LPL lipoprotein lipase decreases expression ISO beta Carotene results in decreased expression of LPL mRNA CTD PMID:21569430 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 increases phosphorylation
multiple interactions
EXP
ISO
beta Carotene results in increased phosphorylation of MAPK1 protein
beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]
CTD PMID:16206275 PMID:27154496 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 increases phosphorylation
multiple interactions
EXP
ISO
beta Carotene results in increased phosphorylation of MAPK3 protein
beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]
CTD PMID:16206275 PMID:27154496 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MBL2 mannose binding lectin 2 multiple interactions EXP MBL2 gene polymorphism affects the susceptibility to [Vitamin A co-treated with beta Carotene] CTD PMID:16960176 NCBI chr10:52,765,380...52,772,784
Ensembl chr10:52,765,380...52,772,784
JBrowse link
G MCL1 MCL1 apoptosis regulator, BCL2 family member affects expression EXP beta Carotene affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738
JBrowse link
G MEIS2 Meis homeobox 2 increases expression EXP beta Carotene results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr15:36,889,204...37,101,311
Ensembl chr15:36,889,204...37,101,299
JBrowse link
G MEOX1 mesenchyme homeobox 1 increases expression EXP beta Carotene results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr17:43,640,389...43,661,922
Ensembl chr17:43,640,389...43,661,922
JBrowse link
G METTL21A methyltransferase 21A, HSPA lysine multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL21A mRNA CTD PMID:24657404 NCBI chr 2:207,580,635...207,626,053
Ensembl chr 2:207,580,631...207,625,928
JBrowse link
G METTL9 methyltransferase like 9 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL9 mRNA CTD PMID:24657404 NCBI chr16:21,597,208...21,657,471
Ensembl chr16:21,597,218...21,657,471
JBrowse link
G MGMT O-6-methylguanine-DNA methyltransferase affects response to substance EXP MGMT gene SNP affects the susceptibility to beta Carotene CTD PMID:16014702 NCBI chr10:129,467,241...129,770,983
Ensembl chr10:129,467,190...129,770,983
JBrowse link
G MKI67 marker of proliferation Ki-67 multiple interactions ISO [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA CTD PMID:23859036 NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
JBrowse link
G MNX1 motor neuron and pancreas homeobox 1 increases expression EXP beta Carotene results in increased expression of MNX1 mRNA CTD PMID:17034753 NCBI chr 7:157,004,854...157,010,663
Ensembl chr 7:156,994,051...157,010,663
JBrowse link
G MPO myeloperoxidase multiple interactions ISO [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein] CTD PMID:31022331 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MRPL57 mitochondrial ribosomal protein L57 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MRPL57 mRNA CTD PMID:24657404 NCBI chr13:21,176,658...21,179,084
Ensembl chr13:21,176,658...21,179,084
JBrowse link
G MSH5 mutS homolog 5 increases expression EXP beta Carotene results in increased expression of MSH5 mRNA CTD PMID:17034753 NCBI chr 6:31,740,005...31,762,676
Ensembl chr 6:31,739,677...31,762,676
JBrowse link
G MTCH2 mitochondrial carrier 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MTCH2 mRNA CTD PMID:24657404 NCBI chr11:47,604,317...47,642,559
Ensembl chr11:47,617,315...47,642,607
JBrowse link
G MUC5AC mucin 5AC, oligomeric mucus/gel-forming increases expression EXP beta Carotene results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138
JBrowse link
G NCKAP1 NCK associated protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NCKAP1 mRNA CTD PMID:24657404 NCBI chr 2:182,909,115...183,038,457
Ensembl chr 2:182,909,115...183,038,858
JBrowse link
G NOM1 nucleolar protein with MIF4G domain 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NOM1 mRNA CTD PMID:24657404 NCBI chr 7:156,949,712...156,973,176
Ensembl chr 7:156,949,712...156,973,176
JBrowse link
G NOS1 nitric oxide synthase 1 increases expression EXP beta Carotene results in increased expression of NOS1 mRNA CTD PMID:17034753 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA] CTD PMID:18779489 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions
increases activity
EXP beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
beta Carotene results in increased activity of NR1I2 protein
CTD PMID:15949683 PMID:16632523 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 increases expression EXP beta Carotene results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138
JBrowse link
G PARD6A par-6 family cell polarity regulator alpha multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PARD6A mRNA CTD PMID:24657404 NCBI chr16:67,660,960...67,662,774
Ensembl chr16:67,660,946...67,662,774
JBrowse link
G PCDH1 protocadherin 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PCDH1 mRNA CTD PMID:24657404 NCBI chr 5:141,853,090...141,878,410
Ensembl chr 5:141,853,090...141,879,246
JBrowse link
G PCDHGC3 protocadherin gamma subfamily C, 3 increases expression EXP beta Carotene results in increased expression of PCDHGC3 mRNA CTD PMID:17034753 NCBI chr 5:141,475,966...141,512,975
Ensembl chr 5:141,475,947...141,512,977
JBrowse link
G PDGFRB platelet derived growth factor receptor beta multiple interactions ISO [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein CTD PMID:23859036 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872
JBrowse link
G PIK3R5 phosphoinositide-3-kinase regulatory subunit 5 increases expression ISO beta Carotene results in increased expression of PIK3R5 protein CTD PMID:20025956 NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,712
JBrowse link
G PLAT plasminogen activator, tissue type multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PLAT mRNA CTD PMID:24657404 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
JBrowse link
G PLSCR1 phospholipid scramblase 1 increases expression EXP beta Carotene results in increased expression of PLSCR1 mRNA CTD PMID:17034753 NCBI chr 3:146,515,180...146,544,607
Ensembl chr 3:146,515,180...146,544,856
JBrowse link
G PLSCR3 phospholipid scramblase 3 increases expression EXP beta Carotene results in increased expression of PLSCR3 mRNA CTD PMID:17034753 NCBI chr17:7,389,727...7,394,525
Ensembl chr17:7,389,727...7,394,842
JBrowse link
G PLSCR4 phospholipid scramblase 4 increases expression EXP beta Carotene results in increased expression of PLSCR4 mRNA CTD PMID:17034753 NCBI chr 3:146,192,335...146,251,105
Ensembl chr 3:146,192,335...146,251,179
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha decreases expression ISO beta Carotene results in decreased expression of PPARA mRNA CTD PMID:21569430 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression ISO beta Carotene results in decreased expression of PPARG mRNA CTD PMID:21569430 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G RAD51AP1 RAD51 associated protein 1 decreases expression EXP beta Carotene results in decreased expression of RAD51AP1 mRNA CTD PMID:17034753 NCBI chr12:4,538,890...4,560,047
Ensembl chr12:4,538,798...4,560,047
JBrowse link
G RAD51D RAD51 paralog D increases expression EXP beta Carotene results in increased expression of RAD51D mRNA CTD PMID:17034753 NCBI chr17:35,092,221...35,119,860
Ensembl chr17:35,092,221...35,121,522
JBrowse link
G RARA retinoic acid receptor alpha decreases expression EXP beta Carotene results in decreased expression of RARA mRNA CTD PMID:17034753 NCBI chr17:40,309,180...40,357,643
Ensembl chr17:40,309,180...40,357,643
JBrowse link
G RARB retinoic acid receptor beta increases expression EXP beta Carotene results in increased expression of RARB mRNA CTD PMID:17034753 NCBI chr 3:24,829,321...25,597,932
Ensembl chr 3:24,687,887...25,597,932
JBrowse link
G RARRES1 retinoic acid receptor responder 1 increases expression EXP beta Carotene results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 3:158,696,892...158,732,457
Ensembl chr 3:158,696,892...158,732,489
JBrowse link
G RBP4 retinol binding protein 4 multiple interactions ISO
EXP
beta Carotene results in decreased expression of and results in decreased secretion of RBP4 protein CTD PMID:22542753 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit decreases phosphorylation EXP beta Carotene results in decreased phosphorylation of RELA protein CTD PMID:26733226 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G RPP14 ribonuclease P/MRP subunit p14 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RPP14 mRNA CTD PMID:24657404 NCBI chr 3:58,306,245...58,320,193
Ensembl chr 3:58,306,245...58,324,695
JBrowse link
G RRM1 ribonucleotide reductase catalytic subunit M1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RRM1 mRNA CTD PMID:24657404 NCBI chr11:4,094,685...4,138,932
Ensembl chr11:4,094,707...4,138,932
JBrowse link
G RXRA retinoid X receptor alpha multiple interactions EXP beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585
JBrowse link
G SCARB1 scavenger receptor class B member 1 increases transport EXP SCARB1 protein results in increased transport of beta Carotene CTD PMID:16177187 NCBI chr12:124,776,856...124,863,864
Ensembl chr12:124,776,856...124,882,668
JBrowse link
G SIX6 SIX homeobox 6 increases expression EXP beta Carotene results in increased expression of SIX6 mRNA CTD PMID:17034753 NCBI chr14:60,509,146...60,512,850
Ensembl chr14:60,509,146...60,512,850
JBrowse link
G SLC2A4 solute carrier family 2 member 4 decreases expression ISO beta Carotene results in decreased expression of SLC2A4 mRNA CTD PMID:21569430 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257
JBrowse link
G SOD1 superoxide dismutase 1 decreases expression EXP beta Carotene results in decreased expression of SOD1 mRNA CTD PMID:17034753 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions ISO [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein] CTD PMID:18779489 PMID:23859036 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SPTLC2 serine palmitoyltransferase long chain base subunit 2 affects expression EXP beta Carotene affects the expression of SPTLC2 mRNA CTD PMID:17034753 NCBI chr14:77,505,997...77,616,637
Ensembl chr14:77,505,997...77,616,637
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 increases expression EXP beta Carotene results in increased expression of SREBF1 mRNA CTD PMID:17034753 NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G TFCP2 transcription factor CP2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TFCP2 mRNA CTD PMID:24657404 NCBI chr12:51,093,656...51,173,135
Ensembl chr12:51,093,656...51,173,135
JBrowse link
G TGM2 transglutaminase 2 increases expression EXP beta Carotene results in increased expression of TGM2 mRNA CTD PMID:17034753 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578
JBrowse link
G TGM4 transglutaminase 4 increases expression EXP beta Carotene results in increased expression of TGM4 mRNA CTD PMID:17034753 NCBI chr 3:44,874,608...44,914,990
Ensembl chr 3:44,874,608...44,914,990
JBrowse link
G THOC7 THO complex 7 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of THOC7 mRNA CTD PMID:24657404 NCBI chr 3:63,833,870...63,864,484
Ensembl chr 3:63,833,870...63,863,868
JBrowse link
G TMEM209 transmembrane protein 209 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TMEM209 mRNA CTD PMID:24657404 NCBI chr 7:130,164,713...130,205,406
Ensembl chr 7:130,164,713...130,207,770
JBrowse link
G TNF tumor necrosis factor multiple interactions EXP
ISO
beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]]; Quercetin affects the reaction [beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]]
beta Carotene promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:19135038 PMID:21447443 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFRSF9 TNF receptor superfamily member 9 increases expression EXP beta Carotene results in increased expression of TNFRSF9 mRNA CTD PMID:17034753 NCBI chr 1:7,915,871...7,940,839
Ensembl chr 1:7,915,871...7,943,165
JBrowse link
G TNFSF10 TNF superfamily member 10 increases expression EXP beta Carotene results in increased expression of TNFSF10 mRNA CTD PMID:17034753 NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475
JBrowse link
G TTC21B tetratricopeptide repeat domain 21B multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TTC21B mRNA CTD PMID:24657404 NCBI chr 2:165,873,362...165,953,776
Ensembl chr 2:165,857,475...165,953,851
JBrowse link
G TWF1 twinfilin actin binding protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TWF1 mRNA CTD PMID:24657404 NCBI chr12:43,793,723...43,806,317
Ensembl chr12:43,793,723...43,806,328
JBrowse link
G TXNDC9 thioredoxin domain containing 9 increases expression EXP beta Carotene results in increased expression of TXNDC9 mRNA CTD PMID:17034753 NCBI chr 2:99,306,184...99,336,333
Ensembl chr 2:99,318,982...99,340,702
JBrowse link
G TYMP thymidine phosphorylase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TYMP mRNA CTD PMID:24657404 NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032
JBrowse link
G XRCC3 X-ray repair cross complementing 3 increases expression EXP beta Carotene results in increased expression of XRCC3 mRNA CTD PMID:17034753 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504
JBrowse link
G YTHDC2 YTH domain containing 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of YTHDC2 mRNA CTD PMID:24657404 NCBI chr 5:113,513,694...113,595,284
Ensembl chr 5:113,513,694...113,595,285
JBrowse link
G ZDHHC3 zinc finger DHHC-type palmitoyltransferase 3 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ZDHHC3 mRNA CTD PMID:24657404 NCBI chr 3:44,915,261...44,976,174
Ensembl chr 3:44,915,257...44,976,185
JBrowse link
bixin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFE2L2 NFE2 like bZIP transcription factor 2 decreases ubiquitination EXP bixin results in decreased ubiquitination of NFE2L2 protein CTD PMID:30698894 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
canthaxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases expression ISO Canthaxanthin results in increased expression of CYP1A1 mRNA CTD PMID:9271336 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 increases expression ISO Canthaxanthin results in increased expression of CYP1A2 mRNA CTD PMID:9271336 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
capsanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GJA1 gap junction protein alpha 1 multiple interactions ISO capsanthin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GJA1 mRNA]; capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GJA1 protein] CTD PMID:27154496 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:27154496 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:27154496 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
carotenoid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BCO2 beta-carotene oxygenase 2 decreases metabolic processing
multiple interactions
ISO BCO2 gene mutant form results in decreased metabolism of Carotenoids
[[BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids] which results in increased expression of SOD2 protein; [BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids; BCO2 protein results in increased oxidation of and results in increased cleavage of Carotenoids
CTD PMID:21106934 NCBI chr11:112,175,512...112,218,946
Ensembl chr11:112,175,510...112,224,699
JBrowse link
G CAT catalase increases activity ISO Carotenoids results in increased activity of CAT protein CTD PMID:29205955 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 affects response to substance EXP CYP1A2 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
JBrowse link
G NAT1 N-acetyltransferase 1 affects response to substance EXP NAT1 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr 8:18,170,467...18,223,689
Ensembl chr 8:18,170,477...18,223,689
JBrowse link
G NAT2 N-acetyltransferase 2 affects response to substance EXP NAT2 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr 8:18,386,301...18,401,218
Ensembl chr 8:18,391,282...18,401,218
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression ISO Carotenoids results in decreased expression of PPARG mRNA CTD PMID:11237167 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G RARG retinoic acid receptor gamma increases expression ISO Carotenoids results in increased expression of RARG mRNA CTD PMID:11237167 NCBI chr12:53,210,569...53,232,209
Ensembl chr12:53,210,567...53,232,980
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
increases expression
ISO [[BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids] which results in increased expression of SOD2 protein
Carotenoids results in increased expression of SOD2 protein
CTD PMID:21106934 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
crocin-1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACP5 acid phosphatase 5, tartrate resistant multiple interactions ISO crocin promotes the reaction [pyrazolanthrone inhibits the reaction [TNFSF11 protein results in increased activity of ACP5 protein]] CTD PMID:30580027 NCBI chr19:11,574,660...11,578,975
Ensembl chr19:11,574,653...11,579,993
JBrowse link
G AKT2 AKT serine/threonine kinase 2 multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of AKT2 mRNA] CTD PMID:30580027 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor multiple interactions ISO crocin inhibits the reaction [Cisplatin results in decreased expression of BAMBI mRNA] CTD PMID:32259551 NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions
increases expression
ISO
EXP
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; crocin inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; crocin inhibits the reaction [Diazinon results in increased expression of BAX protein]
crocin results in increased expression of BAX mRNA
CTD PMID:23523949 PMID:27353299 PMID:32886819 PMID:32920515 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
decreases expression
ISO
EXP
[crocin co-treated with Paraquat] results in decreased expression of BCL2 mRNA
crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]
crocin results in decreased expression of BCL2 mRNA
CTD PMID:31911963 PMID:32886819 PMID:32920515 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BDNF brain derived neurotrophic factor increases expression ISO crocin results in increased expression of BDNF mRNA; crocin results in increased expression of BDNF protein CTD PMID:24401376 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 decreases expression EXP crocin results in decreased expression of BIRC5 mRNA CTD PMID:32886819 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
JBrowse link
G CASP3 caspase 3 multiple interactions
increases activity
increases expression
increases cleavage
ISO
EXP
crocin affects the reaction [Ethanol results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased cleavage of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased expression of CASP3 protein modified form]; crocin inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; crocin inhibits the reaction [Ethanol results in increased activity of CASP3 protein]
crocin results in increased activity of CASP3 protein
crocin results in increased expression of CASP3 mRNA
crocin inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA]
Acetylcysteine inhibits the reaction [crocin results in increased activity of CASP3 protein]; MIR34A mRNA inhibits the reaction [crocin results in increased activity of CASP3 protein]; MYCN protein inhibits the reaction [crocin results in increased cleavage of CASP3 protein]; PTPN4 protein affects the reaction [crocin results in increased activity of CASP3 protein]
CTD PMID:23523949 PMID:25637687 PMID:25899501 PMID:26807765 PMID:27353299 More... NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 increases activity EXP crocin results in increased activity of CASP8 protein CTD PMID:32886819 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 multiple interactions
increases activity
ISO
EXP
crocin inhibits the reaction [Diazinon results in increased cleavage of CASP9 protein]
crocin results in increased activity of CASP9 protein
CTD PMID:27353299 PMID:32886819 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions
decreases activity
increases activity
ISO
EXP
crocin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; crocin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
crocin results in decreased activity of CAT protein
crocin inhibits the reaction [Patulin results in increased activity of CAT protein]
crocin results in increased activity of CAT protein
CTD PMID:25899501 PMID:26584762 PMID:29409856 PMID:32886819 PMID:32920515 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCND1 cyclin D1 decreases expression EXP crocin results in decreased expression of CCND1 mRNA CTD PMID:32886819 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CKM creatine kinase, M-type multiple interactions ISO crocin inhibits the reaction [Diazinon results in increased activity of CKM protein] CTD PMID:23523949 NCBI chr19:45,306,413...45,322,875
Ensembl chr19:45,306,413...45,322,875
JBrowse link
G COL2A1 collagen type II alpha 1 chain multiple interactions ISO [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Citric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of phenylacetylglycine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uridine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein] CTD PMID:24709313 NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions ISO crocin results in increased expression of and results in increased phosphorylation of CREB1 protein CTD PMID:24401376 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CYCS cytochrome c, somatic multiple interactions ISO crocin inhibits the reaction [Diazinon affects the localization of CYCS protein] CTD PMID:23523949 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions
decreases activity
ISO crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein]
crocin results in decreased activity of CYP2E1 protein
CTD PMID:25899501 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G GLO1 glyoxalase I multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of GLO1 protein] CTD PMID:30580027 NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145
JBrowse link
G GPT glutamic--pyruvic transaminase multiple interactions ISO crocin inhibits the reaction [Cisplatin results in increased activity of GPT protein] CTD PMID:32259551 NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions ISO crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein] CTD PMID:32920515 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like multiple interactions ISO crocin inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA] CTD PMID:25637687 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283
JBrowse link
G IL10 interleukin 10 multiple interactions ISO crocin inhibits the reaction [Doxorubicin results in decreased expression of IL10 protein] CTD PMID:26807765 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein] CTD PMID:24709313 PMID:26807765 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL6 interleukin 6 multiple interactions
decreases expression
ISO
EXP
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]; crocin inhibits the reaction [Ethanol results in decreased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
crocin results in decreased expression of IL6 mRNA
CTD PMID:25637687 PMID:25899501 PMID:29409856 PMID:32886819 PMID:32920515 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G JAK2 Janus kinase 2 multiple interactions EXP crocin affects the expression of and affects the phosphorylation of JAK2 protein CTD PMID:32886819 NCBI chr 9:4,984,390...5,129,948
Ensembl chr 9:4,984,390...5,129,948
JBrowse link
G KEAP1 kelch like ECH associated protein 1 multiple interactions ISO crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558
JBrowse link
G LDLR low density lipoprotein receptor multiple interactions ISO crocin inhibits the reaction [Diazinon results in decreased expression of LDLR mRNA] CTD PMID:24132704 NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,462...11,133,820
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
ISO
EXP
crocin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; crocin inhibits the reaction [Diazinon results in decreased phosphorylation of MAPK1 protein]
crocin results in decreased phosphorylation of MAPK1 protein
CTD PMID:24132704 PMID:28689058 PMID:32886819 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
ISO
EXP
crocin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; crocin inhibits the reaction [Diazinon results in decreased phosphorylation of MAPK3 protein]
crocin results in decreased phosphorylation of MAPK3 protein
crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of MAPK3 mRNA]
CTD PMID:24132704 PMID:28689058 PMID:30580027 PMID:32886819 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MIR122 microRNA 122 multiple interactions ISO crocin inhibits the reaction [bisphenol A results in increased expression of MIR122 mRNA] CTD PMID:28689058 NCBI chr18:58,451,074...58,451,158
Ensembl chr18:58,451,074...58,451,158
JBrowse link
G MIR29B1 microRNA 29b-1 multiple interactions
increases expression
ISO Cisplatin inhibits the reaction [crocin results in increased expression of MIR29B1 mRNA]; crocin inhibits the reaction [Cisplatin results in decreased expression of MIR29B1 mRNA] CTD PMID:32259551 NCBI chr 7:130,877,459...130,877,539
Ensembl chr 7:130,877,459...130,877,539
JBrowse link
G MIR34A microRNA 34a multiple interactions EXP MIR34A mRNA inhibits the reaction [crocin results in increased activity of CASP3 protein]; MIR34A mRNA inhibits the reaction [crocin results in increased expression of PTPN4 protein] CTD PMID:35085590 NCBI chr 1:9,151,668...9,151,777
Ensembl chr 1:9,151,668...9,151,777
JBrowse link
G MPO myeloperoxidase multiple interactions ISO crocin inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:25637687 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935
JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor decreases expression EXP crocin results in decreased expression of MYC mRNA CTD PMID:32886819 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
JBrowse link
G MYCN MYCN proto-oncogene, bHLH transcription factor multiple interactions
decreases response to substance
decreases expression
EXP crocin results in decreased expression of and results in decreased stability of MYCN mRNA; MYCN protein inhibits the reaction [crocin results in increased cleavage of CASP3 protein]; MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein]
MYCN results in decreased susceptibility to crocin
crocin results in decreased expression of MYCN protein
CTD PMID:30672053 NCBI chr 2:15,940,550...15,947,004
Ensembl chr 2:15,940,550...15,947,007
JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor multiple interactions ISO crocin inhibits the reaction [Cisplatin results in increased expression of MYD88 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of MYD88 protein] CTD PMID:32259551 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,478...38,143,024
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions ISO crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; crocin inhibits the reaction [Cisplatin results in decreased expression of NFE2L2 protein] CTD PMID:32259551 PMID:32920515 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 protein] CTD PMID:32920515 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G OSTM1 osteoclastogenesis associated transmembrane protein 1 multiple interactions ISO [crocin co-treated with pyrazolanthrone co-treated with TNFSF11 protein] results in decreased expression of OSTM1 mRNA; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of OSTM1 mRNA] CTD PMID:30580027 NCBI chr 6:108,041,409...108,074,741
Ensembl chr 6:108,029,245...108,165,854
JBrowse link
G PARP1 poly(ADP-ribose) polymerase 1 multiple interactions
increases cleavage
EXP MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein] CTD PMID:30672053 NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 decreases expression EXP crocin results in decreased expression of PTGS2 mRNA CTD PMID:32886819 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G PTPN4 protein tyrosine phosphatase non-receptor type 4 increases expression
multiple interactions
EXP crocin results in increased expression of PTPN4 protein
MIR34A mRNA inhibits the reaction [crocin results in increased expression of PTPN4 protein]; PTPN4 protein affects the reaction [crocin results in increased activity of CASP3 protein]
CTD PMID:35085590 NCBI chr 2:119,759,922...119,984,899
Ensembl chr 2:119,759,922...119,984,899
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions ISO crocin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein]; crocin inhibits the reaction [Streptozocin results in increased expression of RELA protein] CTD PMID:29409856 PMID:32920515 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G SMAD2 SMAD family member 2 multiple interactions
decreases expression
ISO Cisplatin inhibits the reaction [crocin results in decreased expression of SMAD2 protein]; crocin inhibits the reaction [Cisplatin results in increased expression of SMAD2 protein] CTD PMID:32259551 NCBI chr18:47,808,957...47,930,872
Ensembl chr18:47,808,957...47,931,146
JBrowse link
G STAT3 signal transducer and activator of transcription 3 multiple interactions EXP crocin affects the expression of and affects the phosphorylation of STAT3 protein CTD PMID:32886819 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,540
JBrowse link
G TGFB1 transforming growth factor beta 1 multiple interactions ISO crocin inhibits the reaction [Cisplatin results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] CTD PMID:29409856 PMID:32259551 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 multiple interactions ISO crocin inhibits the reaction [Cisplatin results in increased expression of TGFBR1 protein] CTD PMID:32259551 NCBI chr 9:99,104,038...99,154,192
Ensembl chr 9:99,104,038...99,154,192
JBrowse link
G TLR4 toll like receptor 4 multiple interactions ISO crocin inhibits the reaction [Cisplatin results in increased expression of TLR4 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein] CTD PMID:29409856 PMID:32259551 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
JBrowse link
G TNF tumor necrosis factor multiple interactions
decreases expression
ISO
EXP
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; crocin inhibits the reaction [Ethanol results in decreased expression of TNF protein]
crocin results in decreased expression of TNF mRNA
CTD PMID:25637687 PMID:25899501 PMID:26807765 PMID:32886819 PMID:32920515 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFSF11 TNF superfamily member 11 multiple interactions ISO [crocin co-treated with pyrazolanthrone co-treated with TNFSF11 protein] results in decreased expression of OSTM1 mRNA; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of AKT2 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of MAPK3 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of OSTM1 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of TRAF6 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of GLO1 protein]; crocin promotes the reaction [pyrazolanthrone inhibits the reaction [TNFSF11 protein results in increased activity of ACP5 protein]] CTD PMID:30580027 NCBI chr13:42,562,736...42,608,013
Ensembl chr13:42,562,736...42,608,013
JBrowse link
G TNNT2 troponin T2, cardiac type multiple interactions ISO crocin inhibits the reaction [Doxorubicin results in increased expression of TNNT2 protein] CTD PMID:26807765 NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764
JBrowse link
G TP53 tumor protein p53 multiple interactions ISO crocin inhibits the reaction [Paraquat results in increased expression of TRP53 mRNA] CTD PMID:31911963 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TRAF6 TNF receptor associated factor 6 multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of TRAF6 mRNA] CTD PMID:30580027 NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272
JBrowse link
G VGF VGF nerve growth factor inducible increases expression ISO crocin results in increased expression of VGF protein CTD PMID:24401376 NCBI chr 7:101,162,509...101,169,952
Ensembl chr 7:101,162,509...101,165,569
JBrowse link
fucoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOX1 acyl-CoA oxidase 1 increases expression ISO fucoxanthin results in increased expression of ACOX1 mRNA CTD PMID:20519145 NCBI chr17:75,941,507...75,979,166
Ensembl chr17:75,941,507...75,979,177
JBrowse link
G ACTA1 actin alpha 1, skeletal muscle multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ACTA1 mRNA] CTD PMID:33448797 NCBI chr 1:229,431,245...229,434,094
Ensembl chr 1:229,430,365...229,434,104
JBrowse link
G ADCY7 adenylate cyclase 7 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased methylation of ADCY7 gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of ADCY7 mRNA] CTD PMID:33448797 NCBI chr16:50,244,699...50,318,135
Ensembl chr16:50,246,137...50,318,135
JBrowse link
G AK8 adenylate kinase 8 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of AK8 mRNA] CTD PMID:33448797 NCBI chr 9:132,725,578...132,879,046
Ensembl chr 9:132,725,578...132,878,777
JBrowse link
G AKT1 AKT serine/threonine kinase 1 multiple interactions
decreases expression
ISO
EXP
fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein]
fucoxanthin results in decreased expression of AKT1 mRNA
CTD PMID:26418808 PMID:35266250 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALCAM activated leukocyte cell adhesion molecule multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ALCAM mRNA] CTD PMID:33448797 NCBI chr 3:105,366,909...105,576,900
Ensembl chr 3:105,366,909...105,576,900
JBrowse link
G ANKRD61 ankyrin repeat domain 61 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ANKRD61 mRNA] CTD PMID:33448797 NCBI chr 7:6,031,376...6,036,552
Ensembl chr 7:6,031,376...6,036,552
JBrowse link
G ARHGDIB Rho GDP dissociation inhibitor beta multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ARHGDIB mRNA] CTD PMID:33448797 NCBI chr12:14,942,015...14,961,601
Ensembl chr12:14,942,031...14,961,728
JBrowse link
G ARMCX6 armadillo repeat containing X-linked 6 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ARMCX6 mRNA] CTD PMID:33448797 NCBI chr  X:101,615,125...101,618,000
Ensembl chr  X:101,615,118...101,618,001
JBrowse link
G ATG10 autophagy related 10 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ATG10 mRNA] CTD PMID:33448797 NCBI chr 5:81,972,023...82,256,133
Ensembl chr 5:81,972,023...82,276,857
JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ATP2A1 mRNA] CTD PMID:33448797 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
JBrowse link
G BAMBI BMP and activin membrane bound inhibitor multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of BAMBI mRNA] CTD PMID:33448797 NCBI chr10:28,677,521...28,682,932
Ensembl chr10:28,677,510...28,682,932
JBrowse link
G BCHE butyrylcholinesterase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of BCHE mRNA] CTD PMID:33448797 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP fucoxanthin results in decreased expression of BCL2 mRNA CTD PMID:35266250 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 multiple interactions
decreases expression
EXP Acetylcysteine inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein] CTD PMID:20594983 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G CASP3 caspase 3 increases cleavage
multiple interactions
EXP fucoxanthin results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP3 protein]
CTD PMID:20594983 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP7 caspase 7 multiple interactions
increases cleavage
EXP Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein] CTD PMID:20594983 NCBI chr10:113,679,194...113,730,909
Ensembl chr10:113,679,162...113,730,907
JBrowse link
G CASZ1 castor zinc finger 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CASZ1 mRNA] CTD PMID:33448797 NCBI chr 1:10,636,604...10,796,646
Ensembl chr 1:10,636,604...10,796,650
JBrowse link
G CAT catalase multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in decreased activity of CAT protein] CTD PMID:26418808 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCDC116 coiled-coil domain containing 116 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CCDC116 mRNA] CTD PMID:33448797 NCBI chr22:21,632,760...21,637,329
Ensembl chr22:21,632,716...21,637,329
JBrowse link
G CCR10 C-C motif chemokine receptor 10 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CCR10 mRNA] CTD PMID:33448797 NCBI chr17:42,678,889...42,681,843
Ensembl chr17:42,678,889...42,683,917
JBrowse link
G CD1D CD1d molecule multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CD1D1 mRNA] CTD PMID:33448797 NCBI chr 1:158,178,030...158,186,427
Ensembl chr 1:158,178,030...158,186,427
JBrowse link
G CELSR1 cadherin EGF LAG seven-pass G-type receptor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CELSR1 mRNA] CTD PMID:33448797 NCBI chr22:46,361,174...46,537,620
Ensembl chr22:46,360,834...46,537,620
JBrowse link
G CEMIP cell migration inducing hyaluronidase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CEMIP mRNA] CTD PMID:33448797 NCBI chr15:80,779,370...80,951,771
Ensembl chr15:80,779,343...80,951,776
JBrowse link
G CFP complement factor properdin multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CFP mRNA] CTD PMID:33448797 NCBI chr  X:47,623,282...47,630,305
Ensembl chr  X:47,623,172...47,630,305
JBrowse link
G CNN1 calponin 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CNN1 mRNA] CTD PMID:33448797 NCBI chr19:11,538,851...11,550,323
Ensembl chr19:11,538,767...11,550,323
JBrowse link
G COL7A1 collagen type VII alpha 1 chain multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of COL7A1 mRNA] CTD PMID:33448797 NCBI chr 3:48,564,073...48,595,329
Ensembl chr 3:48,564,073...48,595,329
JBrowse link
G CPQ carboxypeptidase Q multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CPQ mRNA] CTD PMID:33448797 NCBI chr 8:96,645,242...97,143,501
Ensembl chr 8:96,645,242...97,149,654
JBrowse link
G CRLF1 cytokine receptor like factor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CRLF1 mRNA] CTD PMID:33448797 NCBI chr19:18,593,237...18,606,799
Ensembl chr19:18,572,220...18,607,741
JBrowse link
G CYP2E1 cytochrome P450 family 2 subfamily E member 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA] CTD PMID:33448797 NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
JBrowse link
G DBIL5P diazepam binding inhibitor-like 5, pseudogene multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of DBIL5 mRNA] CTD PMID:33448797 NCBI chr17:752,333...755,336
Ensembl chr17:752,660...755,336
JBrowse link
G DISP2 dispatched RND transporter family member 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of DISP2 mRNA] CTD PMID:33448797 NCBI chr15:40,358,219...40,378,621
Ensembl chr15:40,358,219...40,378,621
JBrowse link
G DMTN dematin actin binding protein multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of DMTN mRNA] CTD PMID:33448797 NCBI chr 8:22,048,931...22,082,525
Ensembl chr 8:22,048,995...22,082,527
JBrowse link
G DRD3 dopamine receptor D3 increases activity EXP fucoxanthin results in increased activity of DRD3 protein CTD PMID:31323226 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
JBrowse link
G DRD4 dopamine receptor D4 increases activity EXP fucoxanthin results in increased activity of DRD4 protein CTD PMID:31323226 NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
JBrowse link
G DUSP13 dual specificity phosphatase 13 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of DUSP13 mRNA] CTD PMID:33448797 NCBI chr10:75,094,434...75,109,191
Ensembl chr10:75,094,432...75,109,221
JBrowse link
G ELAPOR1 endosome-lysosome associated apoptosis and autophagy regulator 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ELAPOR1 mRNA] CTD PMID:33448797 NCBI chr 1:109,114,115...109,206,781
Ensembl chr 1:109,113,679...109,206,781
JBrowse link
G ESRP1 epithelial splicing regulatory protein 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ESRP1 mRNA] CTD PMID:33448797 NCBI chr 8:94,641,174...94,707,466
Ensembl chr 8:94,641,074...94,707,466
JBrowse link
G FAM78B family with sequence similarity 78 member B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM78B mRNA] CTD PMID:33448797 NCBI chr 1:166,055,918...166,167,001
Ensembl chr 1:166,057,426...166,167,001
JBrowse link
G FAM83C family with sequence similarity 83 member C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of FAM83C mRNA] CTD PMID:33448797 NCBI chr20:35,285,731...35,292,425
Ensembl chr20:35,285,731...35,292,425
JBrowse link
G FAM98C family with sequence similarity 98 member C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM98C mRNA] CTD PMID:33448797 NCBI chr19:38,403,093...38,409,088
Ensembl chr19:38,403,093...38,409,088
JBrowse link
G FBP2 fructose-bisphosphatase 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FBP2 mRNA] CTD PMID:33448797 NCBI chr 9:94,558,720...94,593,824
Ensembl chr 9:94,558,720...94,593,824
JBrowse link
G FCHO1 FCH and mu domain containing endocytic adaptor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FCHO1 mRNA] CTD PMID:33448797 NCBI chr19:17,747,744...17,788,561
Ensembl chr19:17,747,718...17,788,568
JBrowse link
G FGF1 fibroblast growth factor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FGF1 mRNA] CTD PMID:33448797 NCBI chr 5:142,592,178...142,698,070
Ensembl chr 5:142,592,178...142,698,070
JBrowse link
G FGL2 fibrinogen like 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of FGL2 mRNA] CTD PMID:33448797 NCBI chr 7:77,193,369...77,199,819
Ensembl chr 7:77,193,369...77,199,848
JBrowse link
G FLG filaggrin decreases expression ISO fucoxanthin results in decreased expression of FLG mRNA CTD PMID:27590588 NCBI chr 1:152,302,165...152,325,239
Ensembl chr 1:152,302,165...152,325,239
JBrowse link
G GASK1B golgi associated kinase 1B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GASK1B mRNA] CTD PMID:33448797 NCBI chr 4:158,124,474...158,173,025
Ensembl chr 4:158,124,474...158,173,318
JBrowse link
G GJA1 gap junction protein alpha 1 increases expression EXP fucoxanthin results in increased expression of GJA1 mRNA; fucoxanthin results in increased expression of GJA1 protein CTD PMID:19737546 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GJB1 gap junction protein beta 1 increases expression EXP fucoxanthin results in increased expression of GJB1 mRNA; fucoxanthin results in increased expression of GJB1 protein CTD PMID:19737546 NCBI chr  X:71,215,239...71,225,516
Ensembl chr  X:71,212,811...71,225,516
JBrowse link
G GNG2 G protein subunit gamma 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of GNG2 mRNA] CTD PMID:33448797 NCBI chr14:51,826,174...51,969,795
Ensembl chr14:51,826,195...51,979,342
JBrowse link
G GPM6B glycoprotein M6B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GPM6B mRNA] CTD PMID:33448797 NCBI chr  X:13,770,939...13,938,638
Ensembl chr  X:13,770,939...13,938,638
JBrowse link
G GRIN1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GRIN1 mRNA] CTD PMID:33448797 NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,139,154...137,168,756
JBrowse link
G GULOP gulonolactone (L-) oxidase, pseudogene multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GULO mRNA] CTD PMID:33448797 NCBI chr 8:27,577,611...27,589,073
Ensembl chr 8:27,560,274...27,589,073
JBrowse link
G GYPC glycophorin C (Gerbich blood group) multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of GYPC mRNA] CTD PMID:33448797 NCBI chr 2:126,656,158...126,696,667
Ensembl chr 2:126,656,133...126,696,667
JBrowse link
G HHAT hedgehog acyltransferase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of HHAT mRNA] CTD PMID:33448797 NCBI chr 1:210,327,328...210,676,290
Ensembl chr 1:210,328,252...210,676,296
JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO fucoxanthin results in decreased activity of HMGCR protein CTD PMID:20519145 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001
JBrowse link
G HMOX1 heme oxygenase 1 increases expression ISO
EXP
fucoxanthin results in increased expression of HMOX1 protein CTD PMID:23358145 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G HUNK hormonally up-regulated Neu-associated kinase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of HUNK mRNA] CTD PMID:33448797 NCBI chr21:31,873,020...32,004,064
Ensembl chr21:31,873,020...32,044,633
JBrowse link
G ICA1L islet cell autoantigen 1 like multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ICA1L mRNA] CTD PMID:33448797 NCBI chr 2:202,773,176...202,871,766
Ensembl chr 2:202,773,150...202,871,766
JBrowse link
G ICAM5 intercellular adhesion molecule 5 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ICAM5 mRNA] CTD PMID:33448797 NCBI chr19:10,289,952...10,296,778
Ensembl chr19:10,289,952...10,296,778
JBrowse link
G IFI44 interferon induced protein 44 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of IFI44 mRNA] CTD PMID:33448797 NCBI chr 1:78,649,789...78,664,078
Ensembl chr 1:78,649,796...78,664,078
JBrowse link
G IL1B interleukin 1 beta multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:22735499 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
JBrowse link
G IL23R interleukin 23 receptor multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IL23R mRNA] CTD PMID:33448797 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979
JBrowse link
G IL24 interleukin 24 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IL24 mRNA] CTD PMID:33448797 NCBI chr 1:206,897,443...206,904,139
Ensembl chr 1:206,897,443...206,904,139
JBrowse link
G IL6 interleukin 6 multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:22735499 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
JBrowse link
G IRAG1 inositol 1,4,5-triphosphate receptor associated 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IRAG1 mRNA] CTD PMID:33448797 NCBI chr11:10,573,095...10,693,755
Ensembl chr11:10,573,091...10,693,988
JBrowse link
G IRF7 interferon regulatory factor 7 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of IRF7 mRNA] CTD PMID:33448797 NCBI chr11:612,555...615,950
Ensembl chr11:612,553...615,983
JBrowse link
G KCNIP2 potassium voltage-gated channel interacting protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of KCNIP2 mRNA]; fucoxanthin inhibits the reaction [Glucose results in increased methylation of KCNIP2 gene] CTD PMID:33448797 NCBI chr10:101,825,974...101,843,800
Ensembl chr10:101,825,974...101,843,920
JBrowse link
G LPCAT1 lysophosphatidylcholine acyltransferase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of LPCAT1 mRNA] CTD PMID:33448797 NCBI chr 5:1,461,427...1,523,960
Ensembl chr 5:1,456,480...1,523,962
JBrowse link
G LRRC61 leucine rich repeat containing 61 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LRRC61 mRNA] CTD PMID:33448797 NCBI chr 7:150,309,499...150,338,156
Ensembl chr 7:150,323,263...150,338,156
JBrowse link
G LTC4S leukotriene C4 synthase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LTC4S mRNA] CTD PMID:33448797 NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
JBrowse link
G LY96 lymphocyte antigen 96 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LY96 mRNA] CTD PMID:33448797 NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079
JBrowse link
G MAK male germ cell associated kinase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAK mRNA] CTD PMID:33448797 NCBI chr 6:10,762,723...10,838,539
Ensembl chr 6:10,762,723...10,838,553
JBrowse link
G MAMDC2 MAM domain containing 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAMDC2 mRNA] CTD PMID:33448797 NCBI chr 9:70,043,581...70,226,972
Ensembl chr 9:70,043,848...70,226,972
JBrowse link
G MAOA monoamine oxidase A decreases activity EXP fucoxanthin results in decreased activity of MAOA protein CTD PMID:31323226 NCBI chr  X:43,655,006...43,746,817
Ensembl chr  X:43,654,907...43,746,817
JBrowse link
G MAOB monoamine oxidase B decreases activity EXP fucoxanthin results in decreased activity of MAOB protein CTD PMID:31323226 NCBI chr  X:43,766,610...43,882,450
Ensembl chr  X:43,766,610...43,882,450
JBrowse link
G MAP3K13 mitogen-activated protein kinase kinase kinase 13 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAP3K13 mRNA] CTD PMID:33448797 NCBI chr 3:185,282,961...185,489,094
Ensembl chr 3:185,282,941...185,489,094
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein] CTD PMID:26418808 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein] CTD PMID:26418808 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MFSD3 major facilitator superfamily domain containing 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of MFSD3 mRNA] CTD PMID:33448797 NCBI chr 8:144,509,070...144,511,213
Ensembl chr 8:144,509,070...144,511,213
JBrowse link
G MTOR mechanistic target of rapamycin kinase decreases expression EXP fucoxanthin results in decreased expression of MTOR mRNA CTD PMID:35266250 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
JBrowse link
G MYO7B myosin VIIB multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MYO7B mRNA] CTD PMID:33448797 NCBI chr 2:127,535,683...127,637,726
Ensembl chr 2:127,535,683...127,637,729
JBrowse link
G NKD2 NKD inhibitor of WNT signaling pathway 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NKD2 mRNA] CTD PMID:33448797 NCBI chr 5:1,008,802...1,038,943
Ensembl chr 5:1,008,802...1,038,943
JBrowse link
G NOS2 nitric oxide synthase 2 multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein] CTD PMID:22735499 PMID:26418808 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
JBrowse link
G NRBP2 nuclear receptor binding protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NRBP2 mRNA] CTD PMID:33448797 NCBI chr 8:143,829,776...143,840,973
Ensembl chr 8:143,833,583...143,840,973
JBrowse link
G NTM neurotrimin multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of NTM mRNA] CTD PMID:33448797 NCBI chr11:131,370,615...132,336,822
Ensembl chr11:131,370,478...132,336,822
JBrowse link
G NXPE4 neurexophilin and PC-esterase domain family member 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NXPE4 mRNA] CTD PMID:33448797 NCBI chr11:114,570,591...114,678,250
Ensembl chr11:114,570,591...114,595,786
JBrowse link
G OAS3 2'-5'-oligoadenylate synthetase 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of OAS3 mRNA] CTD PMID:33448797 NCBI chr12:112,938,474...112,973,251
Ensembl chr12:112,938,051...112,976,460
JBrowse link
G PACSIN1 protein kinase C and casein kinase substrate in neurons 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PACSIN1 mRNA] CTD PMID:33448797 NCBI chr 6:34,466,076...34,535,223
Ensembl chr 6:34,466,061...34,535,229
JBrowse link
G PCDH17 protocadherin 17 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PCDH17 mRNA] CTD PMID:33448797 NCBI chr13:57,630,108...57,729,311
Ensembl chr13:57,631,744...57,729,311
JBrowse link
G PCDHGB6 protocadherin gamma subfamily B, 6 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PCDHGB6 mRNA] CTD PMID:33448797 NCBI chr 5:141,408,021...141,512,975
Ensembl chr 5:141,408,021...141,512,975
JBrowse link
G PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased methylation of PIP5K1B gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of PIP5K1B mRNA] CTD PMID:33448797 NCBI chr 9:68,705,240...69,009,176
Ensembl chr 9:68,705,240...69,009,176
JBrowse link
G PITPNM3 PITPNM family member 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of PITPNM3 mRNA] CTD PMID:33448797 NCBI chr17:6,451,263...6,556,555
Ensembl chr17:6,451,263...6,556,555
JBrowse link
G PPARA peroxisome proliferator activated receptor alpha increases expression ISO fucoxanthin results in increased expression of PPARA mRNA CTD PMID:20519145 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755
JBrowse link
G PPARG peroxisome proliferator activated receptor gamma decreases expression ISO fucoxanthin results in decreased expression of PPARG mRNA CTD PMID:20519145 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
JBrowse link
G PSEN2 presenilin 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of PSEN2 mRNA] CTD PMID:33448797 NCBI chr 1:226,870,616...226,903,668
Ensembl chr 1:226,870,184...226,927,726
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein] CTD PMID:22735499 PMID:26418808 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RAB40B RAB40B, member RAS oncogene family multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of RAB40B mRNA] CTD PMID:33448797 NCBI chr17:82,654,973...82,698,698
Ensembl chr17:82,654,973...82,698,698
JBrowse link
G RETN resistin decreases expression ISO fucoxanthin results in decreased expression of RETN protein CTD PMID:20519145 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455
JBrowse link
G RIMBP3C RIMS binding protein 3C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of RIMBP3 mRNA] CTD PMID:33448797 NCBI chr22:21,545,666...21,551,461
Ensembl chr22:21,545,666...21,551,461
JBrowse link
G RTP4 receptor transporter protein 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of RTP4 mRNA] CTD PMID:33448797 NCBI chr 3:187,368,385...187,372,076
Ensembl chr 3:187,368,385...187,372,076
JBrowse link
G SHC4 SHC adaptor protein 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of SHC4 mRNA] CTD PMID:33448797 NCBI chr15:48,823,741...48,963,919
Ensembl chr15:48,823,741...48,963,919
JBrowse link
G SLC16A5 solute carrier family 16 member 5 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SLC16A5 mRNA] CTD PMID:33448797 NCBI chr17:75,087,385...75,110,149
Ensembl chr17:75,087,727...75,106,162
JBrowse link
G SLC18A2 solute carrier family 18 member A2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SLC18A2 mRNA] CTD PMID:33448797 NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430
JBrowse link
G SLC6A18 solute carrier family 6 member 18 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of SLC6A18 mRNA] CTD PMID:33448797 NCBI chr 5:1,225,381...1,246,189
Ensembl chr 5:1,225,381...1,246,189
JBrowse link
G STRIP2 striatin interacting protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of STRIP2 mRNA] CTD PMID:33448797 NCBI chr 7:129,434,432...129,488,399
Ensembl chr 7:129,434,432...129,488,399
JBrowse link
G SYN1 synapsin I multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SYN1 mRNA] CTD PMID:33448797 NCBI chr  X:47,571,901...47,619,857
Ensembl chr  X:47,571,901...47,619,857
JBrowse link
G SYNPO2L synaptopodin 2 like multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SYNPO2L mRNA] CTD PMID:33448797 NCBI chr10:73,644,886...73,656,029
Ensembl chr10:73,644,881...73,663,803
JBrowse link
G TGFB1I1 transforming growth factor beta 1 induced transcript 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TGFB1I1 mRNA] CTD PMID:33448797 NCBI chr16:31,472,152...31,477,960
Ensembl chr16:31,471,585...31,477,960
JBrowse link
G THSD7A thrombospondin type 1 domain containing 7A multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of THSD7A mRNA] CTD PMID:33448797 NCBI chr 7:11,370,365...11,832,198
Ensembl chr 7:11,370,365...11,832,198
JBrowse link
G TMEFF1 transmembrane protein with EGF like and two follistatin like domains 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TMEFF1 mRNA]; fucoxanthin inhibits the reaction [Glucose results in increased methylation of TMEFF1 gene] CTD PMID:33448797 NCBI chr 9:100,473,149...100,577,636
Ensembl chr 9:100,473,149...100,577,636
JBrowse link
G TMEM229B transmembrane protein 229B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TMEM229B mRNA] CTD PMID:33448797 NCBI chr14:67,470,269...67,533,850
Ensembl chr14:67,447,084...67,533,739
JBrowse link
G TNF tumor necrosis factor multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:22735499 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
JBrowse link
G TNFSF13 TNF superfamily member 13 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TNFSF13 mRNA] CTD PMID:33448797 NCBI chr17:7,558,282...7,561,601
Ensembl chr17:7,558,292...7,561,608
JBrowse link
G TTC21A tetratricopeptide repeat domain 21A multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TTC21A mRNA] CTD PMID:33448797 NCBI chr 3:39,107,680...39,138,900
Ensembl chr 3:39,107,680...39,138,903
JBrowse link
G WNT7B Wnt family member 7B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of WNT7B mRNA] CTD PMID:33448797 NCBI chr22:45,920,366...45,977,162
Ensembl chr22:45,920,366...45,977,162
JBrowse link
G ZNF521 zinc finger protein 521 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ZFP521 mRNA] CTD PMID:33448797 NCBI chr18:25,061,924...25,352,166
Ensembl chr18:25,061,924...25,352,190
JBrowse link
G ZNF566 zinc finger protein 566 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ZFP566 mRNA] CTD PMID:33448797 NCBI chr19:36,445,119...36,489,561
Ensembl chr19:36,445,119...36,489,902
JBrowse link
G ZXDC ZXD family zinc finger C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ZXDA mRNA] CTD PMID:33448797 NCBI chr 3:126,437,601...126,475,891
Ensembl chr 3:126,437,601...126,475,891
JBrowse link
lutein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of ALS2 mRNA; [Cisplatin co-treated with Lutein] results in increased expression of ALS2 mRNA
Lutein results in decreased expression of ALS2 mRNA
CTD PMID:24865317 NCBI chr 2:201,700,267...201,780,933
Ensembl chr 2:201,700,267...201,782,112
JBrowse link
G APC APC regulator of WNT signaling pathway multiple interactions ISO [Cisplatin co-treated with Lutein] results in increased expression of APC mRNA CTD PMID:24865317 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G AQR aquarius intron-binding spliceosomal factor decreases expression
multiple interactions
ISO Lutein results in decreased expression of AQR mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of AQR mRNA
CTD PMID:24865317 NCBI chr15:34,851,782...34,969,742
Ensembl chr15:34,851,782...34,969,742
JBrowse link
G ATR ATR serine/threonine kinase multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of ATR mRNA
Lutein results in decreased expression of ATR mRNA
CTD PMID:24865317 NCBI chr 3:142,449,235...142,578,733
Ensembl chr 3:142,449,007...142,578,733
JBrowse link
G BAX BCL2 associated X, apoptosis regulator increases expression EXP Lutein results in increased expression of BAX protein CTD PMID:17455471 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCL2 BCL2 apoptosis regulator decreases expression EXP Lutein results in decreased expression of BCL2 protein CTD PMID:17455471 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCL2L1 BCL2 like 1 increases expression EXP Lutein results in increased expression of BCL2L1 protein CTD PMID:10750663 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
JBrowse link
G BCO2 beta-carotene oxygenase 2 increases metabolic processing
affects metabolic processing
multiple interactions
ISO BCO2 protein results in increased metabolism of Lutein
BCO2 protein affects the metabolism of Lutein
[BCO2 protein affects the metabolism of Lutein] which results in increased abundance of 3'-dehydrolutein; [BCO2 protein results in increased metabolism of Lutein] which results in increased chemical synthesis of apocarotenal metabolite
CTD PMID:21106934 NCBI chr11:112,175,512...112,218,946
Ensembl chr11:112,175,510...112,224,699
JBrowse link
G CAT catalase multiple interactions EXP Lutein inhibits the reaction [deoxynivalenol results in increased expression of CAT protein] CTD PMID:20347963 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCND1 cyclin D1 decreases expression EXP Lutein results in decreased expression of CCND1 protein CTD PMID:17718427 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCS copper chaperone for superoxide dismutase increases expression ISO Lutein results in increased expression of CCS mRNA CTD PMID:24865317 NCBI chr11:66,593,185...66,606,019
Ensembl chr11:66,593,153...66,606,019
JBrowse link
G CFD complement factor D decreases expression
decreases secretion
EXP Lutein results in decreased expression of CFD mRNA
Lutein results in decreased secretion of CFD protein
CTD PMID:26504594 NCBI chr19:859,664...863,641
Ensembl chr19:859,453...867,884
JBrowse link
G CKB creatine kinase B multiple interactions ISO Lutein inhibits the reaction [Isoproterenol results in increased activity of CKB protein] CTD PMID:34435724 NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
JBrowse link
G CTSB cathepsin B increases expression
multiple interactions
ISO Lutein results in increased expression of CTSB mRNA
Cisplatin inhibits the reaction [Lutein results in increased expression of CTSB mRNA]
CTD PMID:24865317 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CYBA cytochrome b-245 alpha chain multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of CYBA mRNA
Lutein results in decreased expression of CYBA mRNA
CTD PMID:24865317 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083
JBrowse link
G DES desmin multiple interactions ISO Lutein inhibits the reaction [Isoproterenol results in decreased expression of DES protein] CTD PMID:34435724 NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735
JBrowse link
G ERCC2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression
multiple interactions
ISO Lutein results in decreased expression of ERCC2 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of ERCC2 mRNA
CTD PMID:24865317 NCBI chr19:45,349,837...45,370,573
Ensembl chr19:45,349,837...45,370,918
JBrowse link
G ERCC6 ERCC excision repair 6, chromatin remodeling factor decreases expression ISO Lutein results in decreased expression of ERCC6 mRNA CTD PMID:24865317 NCBI chr10:49,434,881...49,539,538
Ensembl chr10:49,454,168...49,539,538
JBrowse link
G FMO2 flavin containing dimethylaniline monoxygenase 2 decreases expression ISO Lutein results in decreased expression of FMO2 mRNA CTD PMID:24865317 NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686
JBrowse link
G GAB1 GRB2 associated binding protein 1 decreases expression
multiple interactions
ISO Lutein results in decreased expression of GAB1 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of GAB1 mRNA
CTD PMID:24865317 NCBI chr 4:143,336,876...143,474,565
Ensembl chr 4:143,336,762...143,474,568
JBrowse link
G GPX1 glutathione peroxidase 1 multiple interactions
increases expression
ISO Cisplatin inhibits the reaction [Lutein results in increased expression of GPX1 mRNA]; Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of GPX1 mRNA] CTD PMID:22040935 PMID:24865317 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,176...49,358,353
JBrowse link
G GPX2 glutathione peroxidase 2 multiple interactions ISO [Lutein co-treated with Cisplatin] results in increased expression of GPX2 mRNA CTD PMID:24865317 NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746
JBrowse link
G GPX3 glutathione peroxidase 3 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of GPX3 mRNA CTD PMID:24865317 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988
JBrowse link
G GSR glutathione-disulfide reductase increases expression
multiple interactions
ISO Lutein results in increased expression of GSR mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of GSR mRNA
CTD PMID:24865317 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
JBrowse link
G GSTK1 glutathione S-transferase kappa 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of GSTK1 mRNA CTD PMID:24865317 NCBI chr 7:143,263,441...143,269,115
Ensembl chr 7:143,244,093...143,270,854
JBrowse link
G HMOX1 heme oxygenase 1 multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of HMOX1 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of HMOX1 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of HMOX1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]
Lutein results in increased expression of HMOX1 mRNA; Lutein results in increased expression of HMOX1 protein
CTD PMID:25815309 PMID:26187899 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of IDH1 mRNA
Lutein results in decreased expression of IDH1 mRNA
CTD PMID:24865317 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074
JBrowse link
G IFT172 intraflagellar transport 172 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of IFT172 mRNA
Lutein results in decreased expression of IFT172 mRNA
CTD PMID:24865317 NCBI chr 2:27,444,377...27,489,743
Ensembl chr 2:27,444,377...27,489,805
JBrowse link
G KIF9 kinesin family member 9 multiple interactions
increases expression
ISO Lutein promotes the reaction [Cisplatin results in decreased expression of KIF9 mRNA]
Lutein results in increased expression of KIF9 mRNA
CTD PMID:24865317 NCBI chr 3:47,227,998...47,282,799
Ensembl chr 3:47,227,998...47,283,451
JBrowse link
G MB myoglobin increases expression ISO Lutein results in increased expression of MB mRNA CTD PMID:24865317 NCBI chr22:35,606,764...35,623,354
Ensembl chr22:35,606,764...35,637,951
JBrowse link
G MGST1 microsomal glutathione S-transferase 1 multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of MGST1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of MGST1 mRNA] CTD PMID:25815309 PMID:26187899 NCBI chr12:16,347,115...16,593,331
Ensembl chr12:16,347,142...16,609,259
JBrowse link
G MIAT myocardial infarction associated transcript multiple interactions ISO Lutein inhibits the reaction [Isoproterenol results in increased expression of MIAT] CTD PMID:34435724 NCBI chr22:26,657,482...26,676,478
Ensembl chr22:26,646,411...26,676,475
JBrowse link
G MIR200A microRNA 200a multiple interactions ISO Lutein inhibits the reaction [Isoproterenol results in decreased expression of MIR200A mRNA] CTD PMID:34435724 NCBI chr 1:1,167,863...1,167,952
Ensembl chr 1:1,167,863...1,167,952
JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 protein]; Lutein results in increased expression of and affects the localization of NFE2L2 protein
Lutein inhibits the reaction [Isoproterenol results in decreased expression of NFE2L2 protein]
Lutein results in increased expression of NFE2L2 mRNA; Lutein results in increased expression of NFE2L2 protein
CTD PMID:25815309 PMID:26187899 PMID:34435724 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
JBrowse link
G NGB neuroglobin increases expression ISO Lutein results in increased expression of NGB mRNA CTD PMID:24865317 NCBI chr14:77,265,483...77,271,206
Ensembl chr14:77,265,483...77,271,206
JBrowse link
G NOX4 NADPH oxidase 4 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of NOX4 mRNA
Lutein results in decreased expression of NOX4 mRNA
CTD PMID:24865317 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187
JBrowse link
G NOXO1 NADPH oxidase organizer 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of NOXO1 mRNA CTD PMID:24865317 NCBI chr16:1,978,917...1,981,469
Ensembl chr16:1,978,917...1,984,192
JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO [Cisplatin co-treated with Lutein] results in increased expression of NQO1 mRNA; arsenic trioxide promotes the reaction [Lutein results in increased expression of NQO1 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NQO1 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NQO1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NQO1 protein]
Lutein results in increased expression of NQO1 mRNA; Lutein results in increased expression of NQO1 protein
CTD PMID:24865317 PMID:25815309 PMID:26187899 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
JBrowse link
G NUDT15 nudix hydrolase 15 decreases expression
multiple interactions
ISO Lutein results in decreased expression of NUDT15 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of NUDT15 mRNA
CTD PMID:24865317 NCBI chr13:48,037,726...48,052,755
Ensembl chr13:48,037,726...48,047,221
JBrowse link
G NXN nucleoredoxin increases expression
multiple interactions
ISO Lutein results in increased expression of NXN mRNA
Lutein inhibits the reaction [Cisplatin results in increased expression of NXN mRNA]
CTD PMID:24865317 NCBI chr17:799,310...979,776
Ensembl chr17:799,310...979,776
JBrowse link
G PARK7 Parkinsonism associated deglycase multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of PARK7 mRNA CTD PMID:24865317 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505
JBrowse link
G PPP1R15B protein phosphatase 1 regulatory subunit 15B multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of PPP1R15B mRNA
Lutein results in decreased expression of PPP1R15B mRNA
CTD PMID:24865317 NCBI chr 1:204,395,826...204,411,817
Ensembl chr 1:204,396,492...204,411,887
JBrowse link
G PRDX4 peroxiredoxin 4 increases expression ISO Lutein results in increased expression of PRDX4 mRNA CTD PMID:24865317 NCBI chr  X:23,667,493...23,686,397
Ensembl chr  X:23,664,262...23,686,397
JBrowse link
G PRDX5 peroxiredoxin 5 decreases expression ISO Lutein results in decreased expression of PRDX5 mRNA CTD PMID:24865317 NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811
JBrowse link
G PRDX6 peroxiredoxin 6 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of PRDX6 mRNA
Lutein results in decreased expression of PRDX6 mRNA
CTD PMID:24865317 NCBI chr 1:173,477,335...173,488,815
Ensembl chr 1:173,477,330...173,488,815
JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of PTGS1 mRNA CTD PMID:24865317 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 multiple interactions EXP Lutein inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein] CTD PMID:20347963 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit multiple interactions EXP Lutein inhibits the reaction [deoxynivalenol affects the localization of RELA protein]; Lutein inhibits the reaction [deoxynivalenol results in increased expression of RELA protein] CTD PMID:20347963 NCBI chr11:65,653,601...65,662,916
Ensembl chr11:65,653,599...65,663,090
JBrowse link
G SOD1 superoxide dismutase 1 multiple interactions
increases expression
ISO Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD1 mRNA]
Lutein results in increased expression of SOD1 mRNA
CTD PMID:22040935 PMID:24865317 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
JBrowse link
G SOD2 superoxide dismutase 2 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SOD2 mRNA; Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD2 mRNA]
Lutein results in decreased expression of SOD2 mRNA
CTD PMID:22040935 PMID:24865317 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
JBrowse link
G SOD3 superoxide dismutase 3 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SOD3 mRNA
Lutein results in decreased expression of SOD3 mRNA
CTD PMID:24865317 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842
JBrowse link
G SRXN1 sulfiredoxin 1 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SRXN1 mRNA
Lutein results in decreased expression of SRXN1 mRNA
CTD PMID:24865317 NCBI chr20:646,615...653,200
Ensembl chr20:646,615...653,200
JBrowse link
G TNNT2 troponin T2, cardiac type multiple interactions ISO Lutein inhibits the reaction [Isoproterenol results in decreased expression of TNNT2 protein] CTD PMID:34435724 NCBI chr 1:201,359,014...201,377,680
Ensembl chr 1:201,359,008...201,377,764
JBrowse link
G TXN thioredoxin multiple interactions ISO Lutein inhibits the reaction [Isoproterenol results in decreased expression of TXN protein] CTD PMID:34435724 NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
JBrowse link
G TXNIP thioredoxin interacting protein multiple interactions ISO Lutein inhibits the reaction [Isoproterenol results in increased expression of TXNIP protein] CTD PMID:34435724 NCBI chr 1:145,992,435...145,996,579
Ensembl chr 1:145,992,435...145,996,579
JBrowse link
G TXNRD1 thioredoxin reductase 1 decreases expression
multiple interactions
ISO Lutein results in decreased expression of TXNRD1 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of TXNRD1 mRNA
CTD PMID:24865317 NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307
JBrowse link
G UCP3 uncoupling protein 3 increases expression ISO Lutein results in increased expression of UCP3 mRNA CTD PMID:24865317 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085
JBrowse link
G VIM vimentin increases expression ISO Lutein results in increased expression of VIM mRNA CTD PMID:24865317 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593
JBrowse link
G XIRP1 xin actin binding repeat containing 1 increases expression ISO Lutein results in increased expression of XIRP1 mRNA CTD PMID:24865317 NCBI chr 3:39,183,215...39,192,595
Ensembl chr 3:39,183,210...39,192,596
JBrowse link
lycopene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACHE acetylcholinesterase (Cartwright blood group) multiple interactions ISO Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of ACHE protein] CTD PMID:22192907 PMID:26900785 NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974
JBrowse link
G ADD1 adducin 1 decreases expression EXP lycopene results in decreased expression of ADD1 mRNA CTD PMID:16886892 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076
JBrowse link
G AGER advanced glycosylation end-product specific receptor multiple interactions EXP lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein] CTD PMID:22429818 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322
JBrowse link
G AHR aryl hydrocarbon receptor decreases expression EXP lycopene results in decreased expression of AHR mRNA CTD PMID:16886892 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152
JBrowse link
G AIF1 allograft inflammatory factor 1 multiple interactions ISO lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:28974442 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
JBrowse link
G AKT1 AKT serine/threonine kinase 1 decreases phosphorylation EXP lycopene results in decreased phosphorylation of AKT1 protein CTD PMID:17337101 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G ALAD aminolevulinate dehydratase multiple interactions ISO lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein]
lycopene inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]
CTD PMID:17516994 PMID:25682699 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290
JBrowse link
G AR androgen receptor decreases expression EXP lycopene results in decreased expression of AR mRNA CTD PMID:16886892 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ATF6 activating transcription factor 6 multiple interactions ISO Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ATF6 mRNA] CTD PMID:32544411 NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
JBrowse link
G ATG10 autophagy related 10 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG10 mRNA] CTD PMID:30360616 NCBI chr 5:81,972,023...82,256,133
Ensembl chr 5:81,972,023...82,276,857
JBrowse link
G ATG13 autophagy related 13 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG13 mRNA] CTD PMID:30360616 NCBI chr11:46,617,553...46,674,518
Ensembl chr11:46,617,527...46,674,818
JBrowse link
G ATG14 autophagy related 14 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG14 mRNA] CTD PMID:30360616 NCBI chr14:55,366,391...55,411,830
Ensembl chr14:55,366,391...55,411,830
JBrowse link
G ATG16L1 autophagy related 16 like 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA] CTD PMID:30360616 NCBI chr 2:233,251,673...233,295,669
Ensembl chr 2:233,210,051...233,295,674
JBrowse link
G ATG16L2 autophagy related 16 like 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] CTD PMID:30360616 NCBI chr11:72,814,411...72,843,740
Ensembl chr11:72,814,406...72,843,674
JBrowse link
G ATG2B autophagy related 2B multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG2B mRNA] CTD PMID:30360616 NCBI chr14:96,279,195...96,363,341
Ensembl chr14:96,279,195...96,363,341
JBrowse link
G ATG3 autophagy related 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] CTD PMID:30360616 NCBI chr 3:112,532,510...112,561,962
Ensembl chr 3:112,532,510...112,562,046
JBrowse link
G ATG4A autophagy related 4A cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] CTD PMID:30360616 NCBI chr  X:108,088,829...108,154,671
Ensembl chr  X:108,091,668...108,154,671
JBrowse link
G ATG4B autophagy related 4B cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] CTD PMID:30360616 NCBI chr 2:241,637,693...241,673,857
Ensembl chr 2:241,637,213...241,673,857
JBrowse link
G ATG4C autophagy related 4C cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4C mRNA] CTD PMID:30360616 NCBI chr 1:62,784,132...62,865,516
Ensembl chr 1:62,784,132...62,865,516
JBrowse link
G ATG5 autophagy related 5 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG5 mRNA] CTD PMID:30360616 NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
JBrowse link
G ATG7 autophagy related 7 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG7 mRNA] CTD PMID:30360616 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665
JBrowse link
G ATG9A autophagy related 9A multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9A mRNA] CTD PMID:30360616 NCBI chr 2:219,219,380...219,229,636
Ensembl chr 2:219,219,380...219,229,717
JBrowse link
G ATG9B autophagy related 9B multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9B mRNA] CTD PMID:30360616 NCBI chr 7:151,012,209...151,024,499
Ensembl chr 7:151,012,209...151,024,499
JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1A1 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A2 mRNA] CTD PMID:27112537 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591
JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A3 mRNA] CTD PMID:26476475 NCBI chr19:41,966,582...41,994,230
Ensembl chr19:41,966,582...41,997,497
JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A4 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 1:160,151,603...160,186,980
Ensembl chr 1:160,151,586...160,186,980
JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B1 mRNA] CTD PMID:27112537 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992
JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1B2 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr17:7,646,627...7,657,770
Ensembl chr17:7,646,627...7,657,770
JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 multiple interactions ISO lycopene inhibits the reaction [Atrazine affects the expression of ATP1B3 mRNA] CTD PMID:26476475 NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of ATP1B4 mRNA] CTD PMID:26476475 NCBI chr  X:120,362,089...120,383,237
Ensembl chr  X:120,362,085...120,383,249
JBrowse link
G ATP2A1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A1 mRNA] CTD PMID:27112537 NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A2 mRNA] CTD PMID:27112537 NCBI chr12:110,281,247...110,351,093
Ensembl chr12:110,280,756...110,351,093
JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,870...3,964,464
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B1 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,300
JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B2 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007
JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B3 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr  X:153,517,642...153,582,929
Ensembl chr  X:153,517,642...153,582,939
JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B4 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,787...203,744,081
JBrowse link
G ATP2C1 ATPase secretory pathway Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C1 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 3:130,850,595...131,016,712
Ensembl chr 3:130,850,595...131,016,712
JBrowse link
G ATP2C2 ATPase secretory pathway Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2C2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C2 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr16:84,368,538...84,464,187
Ensembl chr16:84,368,527...84,464,187
JBrowse link
G BACH1 BTB domain and CNC homolog 1 increases expression EXP lycopene results in increased expression of BACH1 mRNA CTD PMID:16886892 NCBI chr21:29,298,922...29,361,894
Ensembl chr21:29,194,071...29,630,751
JBrowse link
G BAP1 BRCA1 associated protein 1 increases expression EXP lycopene results in increased expression of BAP1 mRNA CTD PMID:16886892 NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008
JBrowse link
G BAX BCL2 associated X, apoptosis regulator multiple interactions ISO lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]
Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of BAX mRNA]
CTD PMID:26900785 PMID:27871895 PMID:31568845 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
JBrowse link
G BCHE butyrylcholinesterase multiple interactions ISO Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of BCHE protein] CTD PMID:26900785 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462
JBrowse link
G BCL2 BCL2 apoptosis regulator multiple interactions
increases expression
ISO [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in decreased expression of BCL2 mRNA]
Lycopene results in increased expression of BCL2 mRNA
lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]
CTD PMID:16030430 PMID:26900785 PMID:27871895 PMID:31568845 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
JBrowse link
G BCO1 beta-carotene oxygenase 1 multiple interactions ISO BCO1 affects the reaction [lycopene results in decreased abundance of Testosterone] CTD PMID:21935922 NCBI chr16:81,238,689...81,291,142
Ensembl chr16:81,238,689...81,291,142
JBrowse link
G BDNF brain derived neurotrophic factor multiple interactions ISO lycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]; lycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein]
Lycopene inhibits the reaction [Oxaliplatin results in decreased expression of BDNF protein]
CTD PMID:28974442 PMID:32544411 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BECN1 beclin 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of BECN1 mRNA] CTD PMID:30360616 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase decreases expression EXP lycopene results in decreased expression of BRAF protein CTD PMID:17337101 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G C1QA complement C1q A chain decreases expression ISO lycopene results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 1:22,636,463...22,639,678
Ensembl chr 1:22,635,077...22,639,678
JBrowse link
G C4B complement C4B (Chido blood group) decreases expression ISO lycopene results in decreased expression of C4B mRNA CTD PMID:19555370 NCBI chr 6:32,014,795...32,035,418
Ensembl chr 6:32,014,795...32,035,418
JBrowse link
G CALCA calcitonin related polypeptide alpha multiple interactions ISO Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CALCA protein] CTD PMID:33592256 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,668...14,972,351
JBrowse link
G CASP3 caspase 3 multiple interactions ISO [S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA]
lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA]
CTD PMID:16030430 PMID:27102619 PMID:27871895 PMID:31568845 PMID:32544411 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
JBrowse link
G CASP8 caspase 8 multiple interactions
decreases expression
ISO
EXP
[S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]
lycopene results in decreased expression of CASP8 mRNA
CTD PMID:16030430 PMID:16886892 NCBI chr 2:201,233,443...201,287,711
Ensembl chr 2:201,233,443...201,361,836
JBrowse link
G CASP9 caspase 9 multiple interactions ISO lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP9 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA] CTD PMID:27871895 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
JBrowse link
G CAT catalase multiple interactions
decreases expression
increases activity
increases expression
ISO
EXP
Lycopene affects the reaction [Doxorubicin affects the activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Cadmium Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA]
Lycopene results in decreased expression of CAT mRNA
Lycopene inhibits the reaction [Acetaminophen results in increased activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]
lycopene results in increased activity of CAT protein
lycopene results in increased expression of CAT
CTD PMID:16325981 PMID:17516994 PMID:17873360 PMID:19450652 PMID:20074268 More... NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
JBrowse link
G CCND1 cyclin D1 multiple interactions
decreases expression
EXP
ISO
Lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein]; Lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]
lycopene results in decreased expression of CCND1 protein
lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein]
CTD PMID:16565789 PMID:17051425 PMID:17337101 PMID:19551842 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CCNE1 cyclin E1 decreases expression
increases expression
EXP lycopene results in decreased expression of CCNE1 protein
lycopene results in increased expression of CCNE1 mRNA
CTD PMID:16886892 PMID:17337101 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
JBrowse link
G CDK1 cyclin dependent kinase 1 decreases expression EXP lycopene results in decreased expression of CDK1 protein CTD PMID:17337101 NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
JBrowse link
G CDK4 cyclin dependent kinase 4 decreases expression EXP lycopene results in decreased expression of CDK4 protein CTD PMID:17337101 NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013
JBrowse link
G CDK5 cyclin dependent kinase 5 decreases expression EXP lycopene results in decreased expression of CDK5 protein CTD PMID:17337101 NCBI chr 7:151,053,815...151,057,897
Ensembl chr 7:151,053,815...151,057,897
JBrowse link
G CDK7 cyclin dependent kinase 7 decreases expression EXP lycopene results in decreased expression of CDK7 protein CTD PMID:17337101 NCBI chr 5:69,234,795...69,277,430
Ensembl chr 5:69,234,795...69,277,430
JBrowse link
G CDK9 cyclin dependent kinase 9 decreases expression EXP lycopene results in decreased expression of CDK9 protein CTD PMID:17337101 NCBI chr 9:127,786,034...127,790,792
Ensembl chr 9:127,785,679...127,790,792
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A multiple interactions EXP lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein] CTD PMID:16565789 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CHGA chromogranin A increases expression EXP lycopene results in increased expression of CHGA mRNA CTD PMID:16886892 NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285
JBrowse link
G CHGB chromogranin B decreases expression EXP lycopene results in decreased expression of CHGB mRNA CTD PMID:16886892 NCBI chr20:5,911,510...5,925,353
Ensembl chr20:5,911,510...5,925,353
JBrowse link
G CKB creatine kinase B multiple interactions ISO Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CKB protein] CTD PMID:26900785 NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
JBrowse link
G CRB1 crumbs cell polarity complex component 1 decreases expression EXP lycopene results in decreased expression of CRB1 mRNA CTD PMID:16886892 NCBI chr 1:197,201,504...197,478,455
Ensembl chr 1:197,268,204...197,478,455
JBrowse link
G CTSS cathepsin S decreases expression ISO lycopene results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 1:150,730,188...150,765,778
Ensembl chr 1:150,730,079...150,765,957
JBrowse link
G CXCL14 C-X-C motif chemokine ligand 14 decreases expression ISO lycopene results in decreased expression of CXCL14 mRNA CTD PMID:19555370 NCBI chr 5:135,570,679...135,578,991
Ensembl chr 5:135,570,679...135,579,279
JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 multiple interactions EXP [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; lycopene inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of CXCL8 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA] CTD PMID:25551565 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716
JBrowse link
G CYB5A cytochrome b5 type A multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYB5A protein] CTD PMID:26775023 NCBI chr18:74,250,846...74,291,963
Ensembl chr18:74,250,846...74,291,973
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions ISO lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 protein] CTD PMID:19071209 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases activity
m