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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:sesterterpene
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Accession:CHEBI:35192 term browser browse the term
Definition:A C25 terpene.
Synonyms:related_synonym: Sesterterpen;   sesterterpenes;   sesterterpeno;   sesterterpenos



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24,25-Dihydroxyvitamin D term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccl2 C-C motif chemokine ligand 2 decreases expression ISO 24,25-Dihydroxyvitamin D 3 results in decreased expression of CCL2 protein CTD PMID:18379402 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions ISO 24,25-Dihydroxyvitamin D 3 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 decreases abundance ISO CYP24A1 gene mutant form results in decreased abundance of 24,25-Dihydroxyvitamin D 3 CTD PMID:22337913 NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
JBrowse link
G Lep leptin decreases expression ISO 24,25-Dihydroxyvitamin D 3 results in decreased expression of LEP protein CTD PMID:18379402 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions
increases response to substance
EXP [resveratrol results in decreased activity of PTGS1 protein] which results in decreased susceptibility to 24,25-Dihydroxyvitamin D 3
PTGS1 protein results in increased susceptibility to 24,25-Dihydroxyvitamin D 3
CTD PMID:10653606 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Pth parathyroid hormone increases expression
decreases expression
ISO
EXP
24,25-Dihydroxyvitamin D 3 results in increased expression of PTH protein
24,25-Dihydroxyvitamin D 3 results in decreased expression of PTH protein
CTD PMID:6760236 PMID:11305809 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO 24,25-Dihydroxyvitamin D 3 inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] CTD PMID:27936102 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Timp2 TIMP metallopeptidase inhibitor 2 decreases expression ISO 24,25-Dihydroxyvitamin D 3 results in decreased expression of TIMP2 protein CTD PMID:18379402 NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611
JBrowse link
G Vdr vitamin D receptor increases activity ISO 24,25-Dihydroxyvitamin D 3 results in increased activity of VDR protein CTD PMID:17997857 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677
JBrowse link
G Vegfd vascular endothelial growth factor D increases expression ISO 24,25-Dihydroxyvitamin D 3 results in increased expression of VEGFD protein CTD PMID:18379402 NCBI chr  X:30,073,122...30,108,413
Ensembl chr  X:30,074,163...30,108,295
JBrowse link
manoalide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO manoalide inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:7575673 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO manoalide inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; manoalide inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] CTD PMID:7575673 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO manoalide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:7575673 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
ophiobolin A term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A multiple interactions ISO ophiobolin A inhibits the reaction [ABCB1 protein results in increased uptake of Digoxin] CTD PMID:16904803 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
JBrowse link
scalaradial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta multiple interactions ISO scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein] CTD PMID:7575673 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Mpo myeloperoxidase multiple interactions ISO scalaradial inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of MPO protein] CTD PMID:8113982 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO scalaradial inhibits the reaction [[Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; scalaradial inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased activity of PTGS2 protein] CTD PMID:7575673 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO scalaradial inhibits the reaction [IL1B protein results in increased expression of TNF protein]; scalaradial inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:7575673 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
taraxerone term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adh1 alcohol dehydrogenase 1C (class I), gamma polypeptide multiple interactions ISO taraxerone promotes the reaction [Ethanol results in increased expression of ADH1 mRNA] CTD PMID:22554647 NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892
JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member multiple interactions ISO taraxerone promotes the reaction [Ethanol results in increased expression of ALDH2 mRNA] CTD PMID:22554647 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521
JBrowse link
G Cat catalase multiple interactions ISO taraxerone inhibits the reaction [Ethanol results in decreased expression of CAT protein] CTD PMID:22554647 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20056
    chemical entity 20055
      atom 20054
        nonmetal atom 19945
          carbon atom 19875
            organic molecular entity 19875
              isoprenoid 13624
                terpene 13624
                  sesterterpene 18
                    (+)-thalianatriene 0
                    (-)-retigeranin B 0
                    24,25-Dihydroxyvitamin D 10
                    25,26-dihydroxyvitamin D 0
                    astellifadiene 0
                    beta-geranylfarnesene 0
                    brassiteraene A 0
                    brassiteraene B 0
                    clavaphyllene 0
                    fusaproliferene 0
                    ophiobolane + 1
                    quiannulatene 0
                    scalarane 0
                    sesterevisene 0
                    sesterorbiculene 0
                    sesterterpenoid + 8
                    stellata-2,6,19-triene 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 20056
    subatomic particle 20054
      composite particle 20054
        hadron 20054
          baryon 20054
            nucleon 20054
              atomic nucleus 20054
                atom 20054
                  main group element atom 19956
                    main group molecular entity 19956
                      s-block molecular entity 19752
                        hydrogen molecular entity 19745
                          hydrides 19114
                            organic hydride 18653
                              organic fundamental parent 18653
                                hydrocarbon 18389
                                  terpene 13624
                                    sesterterpene 18
                                      (+)-thalianatriene 0
                                      (-)-retigeranin B 0
                                      24,25-Dihydroxyvitamin D 10
                                      25,26-dihydroxyvitamin D 0
                                      astellifadiene 0
                                      beta-geranylfarnesene 0
                                      brassiteraene A 0
                                      brassiteraene B 0
                                      clavaphyllene 0
                                      fusaproliferene 0
                                      ophiobolane + 1
                                      quiannulatene 0
                                      scalarane 0
                                      sesterevisene 0
                                      sesterorbiculene 0
                                      sesterterpenoid + 8
                                      stellata-2,6,19-triene 0
paths to the root