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Accession:CHEBI:3515 term browser browse the term
Definition:A 3-(carbamoyloxymethyl)cephalosporin compound having a 7-(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido side chain.
Synonyms:exact_synonym: 3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Cefuroxim;   Cephuroxime;   Formula=C16H16N4O8S;   InChI=1S/C16H16N4O8S/c1-26-19-9(8-3-2-4-27-8)12(21)18-10-13(22)20-11(15(23)24)7(5-28-16(17)25)6-29-14(10)20/h2-4,10,14H,5-6H2,1H3,(H2,17,25)(H,18,21)(H,23,24)/b19-9-/t10-,14-/m1/s1;   InChIKey=JFPVXVDWJQMJEE-IZRZKJBUSA-N;   SMILES=[H][C@]12SCC(COC(N)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1ccco1)C(O)=O;   Sharox;   Zinacef Danmark;   cefuroximo;   cefuroximum
 xref: CAS:55268-75-2 "ChemIDplus";   CAS:55268-75-2 "KEGG COMPOUND";   DrugBank:DB01112;   Drug_Central:565 "DrugCentral";   KEGG:C06894;   KEGG:D00262
 xref_mesh: MESH:D002444
 xref: MetaCyc:CPD0-2069;   PMID:11168076 "Europe PMC";   PMID:11322179 "Europe PMC";   PMID:11581233 "Europe PMC";   PMID:12141712 "Europe PMC";   PMID:12235459 "Europe PMC";   PMID:12833570 "Europe PMC";   PMID:12898829 "Europe PMC";   PMID:14658923 "Europe PMC";   PMID:15052582 "Europe PMC";   PMID:15828440 "Europe PMC";   PMID:16341950 "Europe PMC";   PMID:17111749 "Europe PMC";   PMID:17113884 "Europe PMC";   PMID:17261579 "Europe PMC";   PMID:17366015 "Europe PMC";   PMID:17676080 "Europe PMC";   PMID:18208759 "Europe PMC";   PMID:18611587 "Europe PMC";   PMID:18795089 "Europe PMC";   PMID:18931469 "Europe PMC";   PMID:19069618 "Europe PMC";   PMID:19142482 "Europe PMC";   PMID:19411164 "Europe PMC";   PMID:21425867 "Europe PMC";   PMID:29017833 "Europe PMC";   Patent:DE2439880;   Patent:DE2706413;   Patent:US3974153;   Patent:US4267320;   Reaxys:5783190 "Reaxys";   Wikipedia:Cefuroxime

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cefuroxime term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cat catalase JBrowse link 3 93,379,872 93,412,058 RGD:6480464
G Il10 interleukin 10 JBrowse link 13 47,738,933 47,743,392 RGD:6480464
G Nfe2l2 nuclear factor, erythroid 2-like 2 JBrowse link 3 62,497,568 62,525,146 RGD:6480464
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 JBrowse link 13 89,585,072 89,591,278 RGD:6480464
G Ppara peroxisome proliferator activated receptor alpha JBrowse link 7 126,618,872 126,687,282 RGD:6480464
G RT1-Bb RT1 class II, locus Bb JBrowse link 20 4,043,726 4,049,367 RGD:6480464
G RT1-S3 RT1 class Ib, locus S3 JBrowse link 20 3,176,124 3,180,825 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      application 19246
        pharmaceutical 19108
          drug 19108
            drug allergen 9755
              cefuroxime 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16627
                                              carboxamide 16627
                                                lactam 2856
                                                  beta-lactam 710
                                                    beta-lactam antibiotic 698
                                                      cephem 537
                                                        cephalosporin 536
                                                          3-(carbamoyloxymethyl)cephalosporin 7
                                                            cefuroxime 7
paths to the root


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.