CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: phenethyl isothiocyanate
Accession: CHEBI:351346
browse the term
Definition: An isothiocyanate having a phenethyl group attached to the nitrogen. It is a naturally occurring compound found in some cruciferous vegetables (e.g. watercress) and is known to possess anticancer properties.
Synonyms: related_synonym: (2-Isothiocyanatoethyl)benzene; 2-Phenylethyl isothiocyanate; Formula=C9H9NS; InChI=1S/C9H9NS/c11-8-10-7-6-9-4-2-1-3-5-9/h1-5H,6-7H2; InChIKey=IZJDOKYDEWTZSO-UHFFFAOYSA-N; PEITC; Phenethyl mustard oil; Phenylaethylsenfoel; Phenylethyl isothiocyanate; SMILES=S=C=NCCc1ccccc1; beta-phenethyl isothiocyanate; beta-phenylethyl isothiocyanate
xref: Beilstein:2084162; CAS:2257-09-2; LINCS:LSM-4926
xref_mesh: MESH:C058305
xref: PMID:10636242; PMID:16800772; PMID:19376091; PMID:20371259; PMID:21702500; PMID:21712538; PMID:21739479; PMID:21815843; PMID:22174033; PMID:22266918; PMID:22308101; PMID:22351438; PMID:7562599; Reaxys:2084162; Wikipedia:Phenethyl_isothiocyanate
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6430548M08Rikl
RIKEN cDNA 6430548M08 gene like
increases expression
ISO
phenethyl isothiocyanate results in increased expression of KIAA0513 mRNA
CTD
PMID:26678675
NCBI chr19:48,168,651...48,216,571
Ensembl chr19:48,198,209...48,216,575
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Abcc2
ATP binding cassette subfamily C member 2
affects export multiple interactions
ISO
ABCC2 protein affects the export of phenethyl isothiocyanate Glutathione promotes the reaction [ABCC2 protein affects the export of phenethyl isothiocyanate]
CTD
PMID:16002050
NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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Acat2
acetyl-CoA acetyltransferase 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of ACAT2 mRNA
CTD
PMID:26678675
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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Acta2
actin alpha 2, smooth muscle
affects binding increases expression
ISO
ACTA2 protein binds to phenethyl isothiocyanate phenethyl isothiocyanate results in increased expression of ACTA2 mRNA
CTD
PMID:21838287 PMID:26678675
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Actb
actin, beta
affects binding
ISO
ACTB protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877
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Adam7
ADAM metallopeptidase domain 7
affects binding
ISO
ADAM7 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr15:42,833,796...42,882,201
Ensembl chr15:42,833,796...42,882,201
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Akr7a3
aldo-keto reductase family 7 member A3
increases expression increases activity
EXP
phenethyl isothiocyanate results in increased expression of AKR7A3 mRNA phenethyl isothiocyanate results in increased activity of AKR7A3 protein
CTD
PMID:9328168 PMID:17616710
NCBI chr 5:151,590,968...151,601,394
Ensembl chr 5:151,584,479...151,601,394
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Aldh1a1
aldehyde dehydrogenase 1 family, member A1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of ALDH1A1 protein
CTD
PMID:33211169
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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Anapc15
anaphase promoting complex subunit 15
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of ANAPC15 mRNA
CTD
PMID:26678675
NCBI chr 1:156,238,640...156,266,005
Ensembl chr 1:156,262,841...156,268,145
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Anapc4
anaphase promoting complex subunit 4
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ANAPC4 mRNA
CTD
PMID:17616710
NCBI chr14:58,125,995...58,159,253
Ensembl chr14:58,125,995...58,157,770
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Anxa2-ps1
annexin A2, pseudogene1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ANXA2-PS1 mRNA
CTD
PMID:17616710
NCBI chr15:39,787,844...39,789,055
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Apaf1
apoptotic peptidase activating factor 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of APAF1 protein
CTD
PMID:16054126
NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540
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Arhgap11a
Rho GTPase activating protein 11A
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of ARHGAP11A mRNA
CTD
PMID:26678675
NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559
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Arhgdib
Rho GDP dissociation inhibitor beta
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of ARHGDIB mRNA
CTD
PMID:26678675
NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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Aspm
assembly factor for spindle microtubules
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of ASPM mRNA
CTD
PMID:26678675
NCBI chr13:51,074,849...51,123,755
Ensembl chr13:51,074,849...51,123,755
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Atad5
ATPase family, AAA domain containing 5
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of ATAD5 mRNA
CTD
PMID:26678675
NCBI chr10:65,070,682...65,118,489
Ensembl chr10:65,070,689...65,117,845
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Atp10d
ATPase phospholipid transporting 10D (putative)
increases expression
ISO
phenethyl isothiocyanate results in increased expression of ATP10D mRNA
CTD
PMID:26678675
NCBI chr14:35,911,728...36,012,549
Ensembl chr14:35,912,141...36,012,564
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Atp5f1b
ATP synthase F1 subunit beta
affects binding
ISO
ATP5F1B protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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Atp5me
ATP synthase membrane subunit e
affects binding
ISO
ATP5ME protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
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Atp5mg
ATP synthase membrane subunit G
affects binding
ISO
ATP5MG protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 8:45,225,680...45,233,630
Ensembl chr 8:45,225,686...45,233,559
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Atrx
ATRX, chromatin remodeler
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ATRX mRNA
CTD
PMID:17616710
NCBI chr X:70,850,981...70,997,330
Ensembl chr X:70,850,981...70,997,330
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Aurka
aurora kinase A
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of AURKA mRNA
CTD
PMID:26678675
NCBI chr 3:161,128,309...161,144,524
Ensembl chr 3:161,128,313...161,144,390
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Aurkb
aurora kinase B
increases expression
EXP
phenethyl isothiocyanate results in increased expression of AURKB protein
CTD
PMID:23535288
NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837
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Bax
BCL2 associated X, apoptosis regulator
multiple interactions increases expression
ISO
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [phenethyl isothiocyanate results in increased expression of BAX protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased expression of BAX protein]
CTD
PMID:16054126
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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Baz1b
bromodomain adjacent to zinc finger domain, 1B
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of BAZ1B mRNA
CTD
PMID:17616710
NCBI chr12:21,431,985...21,489,956
Ensembl chr12:21,431,985...21,490,426
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Bcl2
BCL2, apoptosis regulator
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of BCL2 protein
CTD
PMID:16054126
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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Bcl2l1
Bcl2-like 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of BCL2L1 protein
CTD
PMID:16054126
NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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Bdh1
3-hydroxybutyrate dehydrogenase 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of BDH1 mRNA
CTD
PMID:26678675
NCBI chr11:69,302,534...69,343,173
Ensembl chr11:69,302,534...69,337,671
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Bicdl1
BICD family like cargo adaptor 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of BICDL1 mRNA
CTD
PMID:17616710
NCBI chr12:40,878,190...41,001,152
Ensembl chr12:40,876,884...40,966,130
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Bid
BH3 interacting domain death agonist
multiple interactions
ISO
phenethyl isothiocyanate results in increased expression of and results in increased cleavage of BID protein
CTD
PMID:16054126
NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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Blm
BLM RecQ like helicase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of BLM mRNA
CTD
PMID:26678675
NCBI chr 1:134,409,832...134,496,073
Ensembl chr 1:134,409,857...134,484,312
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Blvrb
biliverdin reductase B
increases expression
EXP
phenethyl isothiocyanate results in increased expression of BLVRB mRNA
CTD
PMID:17616710
NCBI chr 1:82,738,646...82,756,312
Ensembl chr 1:82,738,695...82,770,375
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Bod1l1
biorientation of chromosomes in cell division 1-like 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of BOD1L1 mRNA
CTD
PMID:17616710
NCBI chr14:69,108,483...69,163,255
Ensembl chr14:69,108,491...69,162,490
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Brca2
BRCA2, DNA repair associated
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of BRCA2 mRNA
CTD
PMID:26678675
NCBI chr12:59,492...103,789
Ensembl chr12:59,819...100,567
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Brip1
BRCA1 interacting helicase 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of BRIP1 mRNA
CTD
PMID:26678675
NCBI chr10:70,907,266...71,031,502
Ensembl chr10:70,907,371...71,030,324
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Btg2
BTG anti-proliferation factor 2
increases expression
EXP
phenethyl isothiocyanate results in increased expression of BTG2 mRNA
CTD
PMID:17616710
NCBI chr13:45,531,881...45,535,642
Ensembl chr13:45,531,925...45,535,628
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Bub1b
BUB1 mitotic checkpoint serine/threonine kinase B
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of BUB1B mRNA
CTD
PMID:26678675
NCBI chr 3:105,563,089...105,615,547
Ensembl chr 3:105,563,138...105,615,547
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C2h4orf46
similar to human chromosome 4 open reading frame 46
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of C4ORF46 mRNA
CTD
PMID:26678675
NCBI chr 2:164,762,994...164,766,126
Ensembl chr 2:164,762,960...164,766,128
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C5h1orf210
similar to human chromosome 1 open reading frame 210
increases expression
EXP
phenethyl isothiocyanate results in increased expression of C5H1ORF210 mRNA
CTD
PMID:17616710
NCBI chr 5:132,048,755...132,051,913
Ensembl chr 5:132,048,773...132,051,925
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Cab39l
calcium binding protein 39-like
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CAB39L mRNA
CTD
PMID:26678675
NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545
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Calcoco1
calcium binding and coiled coil domain 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CALCOCO1 mRNA
CTD
PMID:26678675
NCBI chr 7:133,834,705...133,849,515
Ensembl chr 7:133,834,707...133,849,422
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Capn2
calpain 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of CAPN2 mRNA
CTD
PMID:17616710
NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969
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Casp3
caspase 3
multiple interactions increases activity
ISO
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [phenethyl isothiocyanate results in increased activity of CASP3 protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in increased activity of CASP3 protein]
CTD
PMID:16054126
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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Casp8
caspase 8
increases activity
ISO
phenethyl isothiocyanate results in increased activity of CASP8 protein
CTD
PMID:16054126
NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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Casp9
caspase 9
increases activity
ISO
phenethyl isothiocyanate results in increased activity of CASP9 protein
CTD
PMID:16054126
NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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Cat
catalase
increases activity
EXP
phenethyl isothiocyanate results in increased activity of CAT protein
CTD
PMID:22664424
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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Cav1
caveolin 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CAV1 mRNA
CTD
PMID:26678675
NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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Cbx5
chromobox 5
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CBX5 mRNA
CTD
PMID:26678675
NCBI chr 7:134,333,165...134,376,102
Ensembl chr 7:134,331,335...134,375,022
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Ccl2
C-C motif chemokine ligand 2
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 mRNA]
CTD
PMID:20423518 PMID:23724058
NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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Ccna2
cyclin A2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CCNA2 protein
CTD
PMID:26678675
NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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Ccnb1
cyclin B1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CCNB1 mRNA; phenethyl isothiocyanate results in decreased expression of CCNB1 protein
CTD
PMID:26678675
NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172
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Ccnd1
cyclin D1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CCND1 protein
CTD
PMID:26678675
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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Ccne1
cyclin E1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CCNE1 protein
CTD
PMID:26678675
NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
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Ccnf
cyclin F
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CCNF mRNA
CTD
PMID:26678675
NCBI chr10:13,253,073...13,279,140
Ensembl chr10:13,253,380...13,279,101
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Ccpg1
cell cycle progression 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CCPG1 mRNA
CTD
PMID:26678675
NCBI chr 8:73,719,960...73,752,437
Ensembl chr 8:73,719,955...73,752,430
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Cct4
chaperonin containing TCP1 subunit 4
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of CCT4 mRNA
CTD
PMID:17616710
NCBI chr14:96,991,853...97,004,732
Ensembl chr14:96,991,859...97,005,267
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Cd40
CD40 molecule
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CD40 mRNA]
CTD
PMID:20423518 PMID:23724058
NCBI chr 3:153,790,372...153,805,279
Ensembl chr 3:153,790,449...153,805,534
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Cd44
CD44 molecule
increases expression
EXP
phenethyl isothiocyanate results in increased expression of CD44 protein
CTD
PMID:33211169
NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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Cd82
Cd82 molecule
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CD82 mRNA
CTD
PMID:26678675
NCBI chr 3:79,387,361...79,431,847
Ensembl chr 3:79,385,887...79,431,809
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Cdc20
cell division cycle 20
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDC20 mRNA
CTD
PMID:26678675
NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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Cdc25c
cell division cycle 25C
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDC25C protein
CTD
PMID:26678675
NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185
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Cdc45
cell division cycle 45
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDC45 mRNA
CTD
PMID:26678675
NCBI chr11:82,185,427...82,210,630
Ensembl chr11:82,185,473...82,210,619
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Cdc6
cell division cycle 6
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDC6 mRNA
CTD
PMID:26678675
NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011
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Cdca3
cell division cycle associated 3
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDCA3 mRNA
CTD
PMID:26678675
NCBI chr 4:157,634,775...157,638,799
Ensembl chr 4:157,634,928...157,638,799
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Cdca7
cell division cycle associated 7
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDCA7 mRNA
CTD
PMID:26678675
NCBI chr 3:57,322,718...57,333,353
Ensembl chr 3:57,322,708...57,333,353
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Cdk1
cyclin-dependent kinase 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of CDK1 protein
CTD
PMID:23535288
NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
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Cdk2
cyclin dependent kinase 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDK2 protein
CTD
PMID:26678675
NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403
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Cdkn1a
cyclin-dependent kinase inhibitor 1A
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CDKN1A mRNA; phenethyl isothiocyanate results in increased expression of CDKN1A protein
CTD
PMID:17937621 PMID:26678675
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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Cdkn3
cyclin-dependent kinase inhibitor 3
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDKN3 mRNA
CTD
PMID:26678675
NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945
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Cdt1
chromatin licensing and DNA replication factor 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CDT1 mRNA
CTD
PMID:26678675
NCBI chr19:50,620,713...50,625,659
Ensembl chr19:50,620,713...50,625,659
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Cenpc
centromere protein C
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of CENPC1 mRNA
CTD
PMID:17616710
NCBI chr14:21,988,067...22,046,732
Ensembl chr14:21,988,144...22,055,476
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Cenpf
centromere protein F
decreases expression
EXP ISO
phenethyl isothiocyanate results in decreased expression of CENPF mRNA
CTD
PMID:17616710 PMID:26678675
NCBI chr13:101,184,127...101,229,714
Ensembl chr13:101,184,127...101,229,669
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Cenpi
centromere protein I
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CENPI mRNA
CTD
PMID:26678675
NCBI chr X:97,515,919...97,567,671
Ensembl chr X:97,515,972...97,567,657
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Chac1
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CHAC1 mRNA
CTD
PMID:26678675
NCBI chr 3:106,342,302...106,345,526
Ensembl chr 3:106,342,302...106,345,526
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Chaf1b
chromatin assembly factor 1 subunit B
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CHAF1B mRNA
CTD
PMID:26678675
NCBI chr11:33,200,894...33,221,076
Ensembl chr11:33,200,981...33,221,070
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Clec14a
C-type lectin domain containing 14A
increases expression
EXP
phenethyl isothiocyanate results in increased expression of CLEC14A mRNA
CTD
PMID:17616710
NCBI chr 6:75,881,470...75,884,612
Ensembl chr 6:75,881,473...75,884,612
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Clspn
claspin
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CLSPN mRNA
CTD
PMID:26678675
NCBI chr 5:138,850,119...138,885,037
Ensembl chr 5:138,850,128...138,885,034
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Clu
clusterin
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CLU mRNA
CTD
PMID:26678675
NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315
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Col4a2
collagen type IV alpha 2 chain
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of COL4A2 mRNA
CTD
PMID:17616710
NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
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Coq2
coenzyme Q2, polyprenyltransferase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of COQ2 mRNA
CTD
PMID:26678675
NCBI chr14:8,941,429...8,961,418
Ensembl chr14:8,941,461...8,960,891
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Cpa6
carboxypeptidase A6
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CPA6 mRNA
CTD
PMID:26678675
NCBI chr 5:8,526,708...8,888,492
Ensembl chr 5:8,526,741...8,888,485
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Crisp1
cysteine-rich secretory protein 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of CRISP1 mRNA
CTD
PMID:17616710
NCBI chr 9:20,741,775...20,768,796
Ensembl chr 9:20,741,777...20,768,796
G
Csf2
colony stimulating factor 2
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF2 mRNA]
CTD
PMID:20423518 PMID:23724058
NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
G
Csf3
colony stimulating factor 3
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CSF3 mRNA]
CTD
PMID:20423518
NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
G
Csnk2b
casein kinase 2 beta
increases expression
EXP
phenethyl isothiocyanate results in increased expression of CSNK2B mRNA
CTD
PMID:17616710
NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
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Ctso
cathepsin O
increases expression
ISO
phenethyl isothiocyanate results in increased expression of CTSO mRNA
CTD
PMID:26678675
NCBI chr 2:167,230,407...167,254,761
Ensembl chr 2:167,230,330...167,253,702
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Cxcl10
C-X-C motif chemokine ligand 10
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL10 mRNA]
CTD
PMID:20423518 PMID:23724058
NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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Cyb5b
cytochrome b5 type B
affects binding
ISO
CYB5B protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr19:35,062,871...35,096,741
Ensembl chr19:35,062,813...35,098,249
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Cycs
cytochrome c, somatic
multiple interactions affects localization
ISO
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [phenethyl isothiocyanate affects the localization of CYCS protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate affects the localization of CYCS protein]
CTD
PMID:16054126
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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Cyp1a1
cytochrome P450, family 1, subfamily a, polypeptide 1
increases expression multiple interactions decreases activity
ISO EXP
phenethyl isothiocyanate results in increased expression of CYP1A1 mRNA phenethyl isothiocyanate results in increased expression of CYP1A1 mRNA; phenethyl isothiocyanate results in increased expression of CYP1A1 protein phenethyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein] phenethyl isothiocyanate results in decreased activity of CYP1A1 protein
CTD
PMID:15672752 PMID:17582584 PMID:20025923 PMID:20442190 PMID:22664424
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
G
Cyp1a2
cytochrome P450, family 1, subfamily a, polypeptide 2
decreases activity increases expression decreases expression multiple interactions
ISO EXP
phenethyl isothiocyanate results in decreased activity of CYP1A2 mRNA phenethyl isothiocyanate results in increased expression of CYP1A2 mRNA phenethyl isothiocyanate results in decreased expression of CYP1A2 protein phenethyl isothiocyanate results in increased activity of [CYP1A1 protein co-treated with CYP1A2 protein]
CTD
PMID:15672752 PMID:20025923 PMID:20442190 PMID:22664424
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
G
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
multiple interactions decreases expression decreases activity
EXP ISO
phenethyl isothiocyanate inhibits the reaction [[CYP2E1 protein results in increased metabolism of Ethanol] which results in increased chemical synthesis of Acetaldehyde]; phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of 4-nitrophenol]; phenethyl isothiocyanate inhibits the reaction [CYP2E1 protein results in increased metabolism of Carbon Tetrachloride]; phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; phenethyl isothiocyanate inhibits the reaction [Ethanol results in increased expression of CYP2E1 protein] phenethyl isothiocyanate results in decreased expression of CYP2E1 protein phenethyl isothiocyanate results in decreased activity of CYP2E1 protein
CTD
PMID:7562599 PMID:7601153 PMID:10616189 PMID:17582584
NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
G
Cyp3a2
cytochrome P450, family 3, subfamily a, polypeptide 2
decreases expression decreases activity increases expression
EXP ISO
phenethyl isothiocyanate results in decreased expression of CYP3A2 mRNA phenethyl isothiocyanate results in decreased activity of CYP3A2 protein phenethyl isothiocyanate results in increased expression of CYP3A4 protein phenethyl isothiocyanate results in decreased expression of CYP3A4 mRNA phenethyl isothiocyanate results in decreased activity of CYP3A4 mRNA
CTD
PMID:20025923 PMID:20442190 PMID:22664424
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
G
Cyp3a9
cytochrome P450, family 3, subfamily a, polypeptide 9
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of CYP3A5 mRNA
CTD
PMID:20442190
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
G
Ddit3
DNA-damage inducible transcript 3
increases expression
ISO
phenethyl isothiocyanate results in increased expression of DDIT3 mRNA
CTD
PMID:26678675
NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
G
Defb1
defensin beta 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of DEFB1 mRNA
CTD
PMID:17616710
NCBI chr16:70,298,862...70,313,604
Ensembl chr16:70,298,863...70,313,604
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Dhcr7
7-dehydrocholesterol reductase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of DHCR7 mRNA
CTD
PMID:26678675
NCBI chr 1:199,015,081...199,031,055
Ensembl chr 1:199,015,081...199,031,055
G
Diablo
diablo, IAP-binding mitochondrial protein
multiple interactions affects localization affects binding
ISO
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [phenethyl isothiocyanate affects the localization of DIABLO protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate affects the localization of DIABLO protein] DIABLO protein binds to phenethyl isothiocyanate
CTD
PMID:16054126 PMID:21838287
NCBI chr12:33,055,784...33,070,401
Ensembl chr12:33,055,263...33,070,387
G
Dio2
iodothyronine deiodinase 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of DIO2 mRNA
CTD
PMID:26678675
NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809
G
Dst
dystonin
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of DST mRNA
CTD
PMID:17616710
NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
G
Dzip3
DAZ interacting zinc finger protein 3
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of DZIP3 mRNA
CTD
PMID:17616710
NCBI chr11:51,823,235...51,893,353
Ensembl chr11:51,823,231...51,893,353
G
Ebp
EBP, cholestenol delta-isomerase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of EBP mRNA
CTD
PMID:26678675
NCBI chr X:14,299,427...14,305,826
Ensembl chr X:14,299,448...14,305,826
G
Ecm1
extracellular matrix protein 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of ECM1 mRNA
CTD
PMID:17616710
NCBI chr 2:183,287,491...183,292,729
Ensembl chr 2:183,287,322...183,292,671
G
Edn1
endothelin 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of EDN1 mRNA
CTD
PMID:26678675
NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
G
Eef1a2
eukaryotic translation elongation factor 1 alpha 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of EEF1A2 mRNA
CTD
PMID:17616710
NCBI chr 3:168,265,893...168,275,071
Ensembl chr 3:168,195,357...168,275,071
G
Eef2
eukaryotic translation elongation factor 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of EEF2 mRNA
CTD
PMID:17616710
NCBI chr 7:8,533,248...8,538,518
Ensembl chr 7:8,533,116...8,559,183
G
Eef2k
eukaryotic elongation factor-2 kinase
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of EEF2K mRNA
CTD
PMID:17616710
NCBI chr 1:175,393,119...175,456,756
Ensembl chr 1:175,393,154...175,455,164
G
Eef2kmt
eukaryotic elongation factor 2 lysine methyltransferase
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of EEF2KMT mRNA
CTD
PMID:17616710
NCBI chr10:10,336,933...10,349,463
Ensembl chr10:10,336,974...10,347,039
G
Egr1
early growth response 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of EGR1 mRNA
CTD
PMID:26678675
NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766
G
Eif2s1
eukaryotic translation initiation factor 2 subunit alpha
increases phosphorylation
ISO
phenethyl isothiocyanate results in increased phosphorylation of EIF2S1 protein
CTD
PMID:27579538
NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
G
Eif3a
eukaryotic translation initiation factor 3, subunit A
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of EIF3A mRNA
CTD
PMID:17616710
NCBI chr 1:259,902,767...259,932,976
Ensembl chr 1:259,902,680...259,932,976
G
Eif4g1
eukaryotic translation initiation factor 4 gamma 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of EIF4G1 mRNA
CTD
PMID:17616710
NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
G
Enc1
ectodermal-neural cortex 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of ENC1 mRNA
CTD
PMID:17616710
NCBI chr 2:28,550,670...28,562,591
Ensembl chr 2:28,550,464...28,562,713
G
Ephx1
epoxide hydrolase 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of EPHX1 protein
CTD
PMID:21132492
NCBI chr13:92,714,315...92,744,105
Ensembl chr13:92,714,315...92,790,235
G
Epn3
epsin 3
increases expression
EXP
phenethyl isothiocyanate results in increased expression of EPN3 mRNA
CTD
PMID:17616710
NCBI chr10:79,438,978...79,449,516
Ensembl chr10:79,438,978...79,447,356
G
Ercc4
ERCC excision repair 4, endonuclease catalytic subunit
increases expression
ISO
phenethyl isothiocyanate results in increased expression of ERCC4 mRNA
CTD
PMID:20442190
NCBI chr10:2,416,259...2,448,364
Ensembl chr10:2,419,038...2,448,369
G
Ercc5
ERCC excision repair 5, endonuclease
increases expression
ISO
phenethyl isothiocyanate results in increased expression of ERCC5 mRNA
CTD
PMID:20442190
NCBI chr 9:46,309,477...46,354,478
Ensembl chr 9:46,309,389...46,354,472
G
Ercc6l
ERCC excision repair 6 like, spindle assembly checkpoint helicase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of ERCC6L mRNA
CTD
PMID:26678675
NCBI chr X:67,245,414...67,261,222
Ensembl chr X:67,245,414...67,280,756
G
Esf1
ESF1 nucleolar pre-rRNA processing protein homolog
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ESF1 mRNA
CTD
PMID:17616710
NCBI chr 3:127,454,744...127,507,941
Ensembl chr 3:127,454,811...127,507,817
G
Espl1
extra spindle pole bodies like 1, separase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of ESPL1 mRNA
CTD
PMID:26678675
NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
G
Etaa1
ETAA1 activator of ATR kinase
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ETAA1 mRNA
CTD
PMID:17616710
NCBI chr14:92,298,461...92,314,044
Ensembl chr14:92,299,553...92,314,104
G
F2rl2
coagulation factor II (thrombin) receptor-like 2
increases expression
ISO
phenethyl isothiocyanate results in increased expression of F2RL2 mRNA
CTD
PMID:26678675
NCBI chr 2:26,972,054...26,977,098
Ensembl chr 2:26,972,054...26,977,098
G
F3
coagulation factor III, tissue factor
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of F3 mRNA
CTD
PMID:26678675
NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
G
Fads2
fatty acid desaturase 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of FADS2 mRNA
CTD
PMID:26678675
NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789
G
Fancd2
FA complementation group D2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of FANCD2 mRNA
CTD
PMID:26678675
NCBI chr 4:146,679,014...146,743,422
Ensembl chr 4:146,679,179...146,743,412
G
Fanci
FA complementation group I
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of FANCI mRNA
CTD
PMID:26678675
NCBI chr 1:133,327,264...133,383,661
Ensembl chr 1:133,327,297...133,383,640
G
Fbxo32
F-box protein 32
increases expression
ISO
phenethyl isothiocyanate results in increased expression of FBXO32 mRNA
CTD
PMID:26678675
NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436
G
Fbxo41
F-box protein 41
affects binding
ISO
FBXO41 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 4:118,007,517...118,039,547
Ensembl chr 4:118,010,978...118,039,406
G
Fen1
flap structure-specific endonuclease 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of FEN1 mRNA
CTD
PMID:26678675
NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003
G
Firrm
FIGNL1 interacting regulator of recombination and mitosis
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of FIRRM mRNA
CTD
PMID:26678675
NCBI chr13:76,301,914...76,345,842
Ensembl chr13:76,301,918...76,345,804
G
Flna
filamin A
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of FLNA mRNA
CTD
PMID:17616710
NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052
G
Fos
Fos proto-oncogene, AP-1 transcription factor subunit
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of FOS mRNA]
CTD
PMID:20423518
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
G
Foxm1
forkhead box M1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of FOXM1 mRNA
CTD
PMID:26678675
NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684
G
Fst
follistatin
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of FST mRNA
CTD
PMID:26678675
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
G
Ftl1
ferritin light chain 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of FTL mRNA
CTD
PMID:26678675
NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725 Ensembl chr10:95,936,387...95,939,725
G
Fxr1
FMR1 autosomal homolog 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of FXR1 mRNA
CTD
PMID:17616710
NCBI chr 2:116,884,167...116,937,590
Ensembl chr 2:116,884,248...116,937,590
G
Gabarapl1
GABA type A receptor associated protein like 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of GABARAPL1 mRNA
CTD
PMID:26678675
NCBI chr 4:162,980,309...162,989,452
Ensembl chr 4:162,980,249...162,989,450
G
Gadd45a
growth arrest and DNA-damage-inducible, alpha
increases expression
ISO
phenethyl isothiocyanate results in increased expression of GADD45A mRNA
CTD
PMID:17937621
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
G
Gclc
glutamate-cysteine ligase, catalytic subunit
increases expression
ISO
phenethyl isothiocyanate results in increased expression of GCLC mRNA
CTD
PMID:20442190
NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
G
Ggh
gamma-glutamyl hydrolase
increases expression
EXP
phenethyl isothiocyanate results in increased expression of GGH mRNA
CTD
PMID:17616710
NCBI chr 5:33,529,880...33,552,790
Ensembl chr 5:33,529,880...33,552,787
G
Gins2
GINS complex subunit 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of GINS2 mRNA
CTD
PMID:26678675
NCBI chr19:48,626,770...48,639,523
Ensembl chr19:48,626,770...48,639,339
G
Giot1
gonadotropin inducible ovarian transcription factor 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of GIOT1 mRNA
CTD
PMID:17616710
NCBI chr 7:10,215,602...10,236,423
Ensembl chr 7:10,202,982...10,237,099
G
Gja1
gap junction protein, alpha 1
multiple interactions increases expression
ISO EXP
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of GJA1 mRNA] phenethyl isothiocyanate results in increased expression of GJA1 mRNA
CTD
PMID:17616710 PMID:20423518
NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
G
Gkn1
gastrokine 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of GKN1 mRNA
CTD
PMID:17616710
NCBI chr 4:119,790,101...119,795,389
Ensembl chr 4:119,790,101...119,795,389
G
Gle1-ps1
GLE1 RNA export mediator, pseudogene 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of GLE1-PS1 mRNA
CTD
PMID:17616710
NCBI chr 6:107,124,892...107,127,024
Ensembl chr 6:107,124,892...107,127,024 Ensembl chr 6:107,124,892...107,127,024
G
Gng5
G protein subunit gamma 5
increases expression
EXP
phenethyl isothiocyanate results in increased expression of GNG5 mRNA
CTD
PMID:17616710
NCBI chr 2:235,394,680...235,403,177
Ensembl chr 1:77,292,043...77,292,513
G
Gsk3b
glycogen synthase kinase 3 beta
multiple interactions increases phosphorylation
ISO
Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased phosphorylation of GSK3B protein]
CTD
PMID:25246272
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
G
Gsn
gelsolin
increases expression
ISO
phenethyl isothiocyanate results in increased expression of GSN mRNA
CTD
PMID:26678675
NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
G
Gsr
glutathione-disulfide reductase
decreases activity increases activity
ISO EXP
phenethyl isothiocyanate results in decreased activity of GSR protein phenethyl isothiocyanate results in increased activity of GSR protein
CTD
PMID:17937621 PMID:22664424
NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
G
Gsta2
glutathione S-transferase alpha 2
increases expression
EXP
phenethyl isothiocyanate results in increased expression of GSTA2 mRNA
CTD
PMID:17616710
NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798
G
Gsta3
glutathione S-transferase alpha 3
increases expression
EXP
phenethyl isothiocyanate results in increased expression of GSTA3 mRNA
CTD
PMID:17616710
NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240
G
Gsta5
glutathione S-transferase alpha 5
increases activity
EXP
phenethyl isothiocyanate results in increased activity of GSTA5 protein
CTD
PMID:9328168
NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
G
Gstm1
glutathione S-transferase mu 1
affects metabolic processing
ISO
GSTM1 protein affects the metabolism of phenethyl isothiocyanate
CTD
PMID:7826396
NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
G
Gstp1
glutathione S-transferase pi 1
affects metabolic processing multiple interactions increases expression
ISO
GSTP1 protein affects the metabolism of phenethyl isothiocyanate [indole-3-carbinol co-treated with phenethyl isothiocyanate] results in increased expression of GSTP1 mRNA; [phenethyl isothiocyanate co-treated with xanthohumol] results in increased expression of GSTP1 mRNA; [phenethyl isothiocyanate co-treated with xanthohumol] results in increased expression of GSTP1 protein phenethyl isothiocyanate results in increased expression of GSTP1 mRNA
CTD
PMID:7826396 PMID:32070777
NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
G
Gstt1
glutathione S-transferase theta 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of GSTT1 protein
CTD
PMID:9855024
NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585
G
Gtse1
G-2 and S-phase expressed 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of GTSE1 mRNA
CTD
PMID:26678675
NCBI chr 7:116,949,997...116,966,826
Ensembl chr 7:116,950,053...116,966,806
G
H2ac12
H2A clustered histone 12
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of H2AC12 mRNA
CTD
PMID:26678675
NCBI chr17:42,486,415...42,486,880
Ensembl chr17:42,486,415...42,486,941
G
H2ac4
H2A clustered histone 4
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of H2AC4 mRNA
CTD
PMID:26678675
NCBI chr17:42,799,884...42,800,387
Ensembl chr17:42,799,652...42,800,381
G
H2bc9
H2B clustered histone 9
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of H2BC9 mRNA
CTD
PMID:26678675
NCBI chr17:42,470,593...42,478,590
G
H3c1
H3 clustered histone 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of H3C1 mRNA
CTD
PMID:26678675
NCBI chr17:41,368,379...41,368,902
Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856 Ensembl chr17:41,368,386...41,368,856
G
H4c14
H4 clustered histone 14
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of H4C2 mRNA
CTD
PMID:26678675
NCBI chr 2:183,831,601...183,831,996
Ensembl chr 2:183,825,994...183,832,048
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Hba-a2
hemoglobin alpha, adult chain 2
increases expression
EXP
phenethyl isothiocyanate results in increased expression of HBA-A2 mRNA
CTD
PMID:17616710
NCBI chr10:15,323,830...15,324,677
Ensembl chr10:15,307,815...15,338,392
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Hdac1
histone deacetylase 1
multiple interactions
EXP
phenethyl isothiocyanate inhibits the reaction [Freund's Adjuvant results in increased expression of HDAC1 protein]
CTD
PMID:32289289
NCBI chr 5:141,853,992...141,881,057
Ensembl chr 5:141,853,989...141,881,111
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Hdlbp
high density lipoprotein binding protein
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of HDLBP mRNA
CTD
PMID:26678675
NCBI chr 9:93,948,099...94,018,040
Ensembl chr 9:93,949,913...94,018,048
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Hells
helicase, lymphoid specific
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of HELLS mRNA
CTD
PMID:26678675
NCBI chr 1:236,701,704...236,748,239
Ensembl chr 1:236,701,758...236,746,844
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Hist1h2bq
histone cluster 1 H2B family member Q
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of H2BC7 mRNA
CTD
PMID:26678675
NCBI chr17:41,432,100...41,441,487
Ensembl chr17:41,429,164...41,442,153
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Hmox1
heme oxygenase 1
increases expression increases activity multiple interactions
ISO EXP
phenethyl isothiocyanate results in increased expression of HMOX1 mRNA phenethyl isothiocyanate results in increased activity of HMOX1 protein NFE2L2 gene mutant form affects the reaction [phenethyl isothiocyanate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]]; phenethyl isothiocyanate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]; phenethyl isothiocyanate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein] 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; 2,2'-Dipyridyl inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; 2,2'-Dipyridyl inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; acetovanillone inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; diphenyleneiodonium inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]]; Glutathione inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Glutathione inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein] phenethyl isothiocyanate results in increased expression of HMOX1 mRNA; phenethyl isothiocyanate results in increased expression of HMOX1 protein
CTD
PMID:20402460 PMID:22664424 PMID:25246272 PMID:25387343 PMID:26945724
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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Hnrnpf
heterogeneous nuclear ribonucleoprotein F
affects binding
ISO
HNRNPF protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 4:151,083,262...151,104,464
Ensembl chr 4:151,083,062...151,109,038
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Hnrnpk
heterogeneous nuclear ribonucleoprotein K
affects binding
ISO
HNRNPK protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997
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Hnrnpr
heterogeneous nuclear ribonucleoprotein R
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of HNRNPR mRNA
CTD
PMID:17616710
NCBI chr 5:148,542,999...148,574,888
Ensembl chr 5:148,543,044...148,574,867
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Hsp90aa1
heat shock protein 90 alpha family class A member 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of HSP90AA1 mRNA
CTD
PMID:17616710
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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Hspa4
heat shock protein family A (Hsp70) member 4
affects binding
ISO
HSPA4 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
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Hspb1
heat shock protein family B (small) member 1
increases expression affects binding
EXP ISO
phenethyl isothiocyanate results in increased expression of HSPB1 mRNA HSPB1 protein binds to phenethyl isothiocyanate
CTD
PMID:17616710 PMID:21838287
NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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Hspe1
heat shock protein family E (Hsp10) member 1
affects binding
ISO
HSPE1 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
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Hsph1
heat shock protein family H (Hsp110) member 1
affects binding
ISO
HSPH1 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
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Il10
interleukin 10
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]
CTD
PMID:20423518
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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Il1a
interleukin 1 alpha
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1A mRNA]
CTD
PMID:20423518
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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Il1b
interleukin 1 beta
multiple interactions decreases expression
ISO
phenethyl isothiocyanate inhibits the reaction [Dextran Sulfate results in increased expression of IL1B protein]; phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] phenethyl isothiocyanate results in decreased expression of IL1B mRNA
CTD
PMID:16373530 PMID:20423518
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il6
interleukin 6
multiple interactions decreases expression
ISO
NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]]; phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of IL6 mRNA]; phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]; phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA] phenethyl isothiocyanate results in decreased expression of IL6 mRNA
CTD
PMID:20423518 PMID:25387343 PMID:26678675
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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Iqgap3
IQ motif containing GTPase activating protein 3
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of IQGAP3 mRNA
CTD
PMID:26678675
NCBI chr 2:173,542,151...173,583,956
Ensembl chr 2:173,542,110...173,583,956
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Jade2
jade family PHD finger 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of JADE2 mRNA
CTD
PMID:17616710
NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984
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Jag1
jagged canonical Notch ligand 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of JAG1 mRNA
CTD
PMID:22039516
NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209
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Jag2
jagged canonical Notch ligand 2
increases expression
ISO
phenethyl isothiocyanate results in increased expression of JAG2 mRNA
CTD
PMID:22039516
NCBI chr 6:131,983,059...132,005,665
Ensembl chr 6:131,983,056...132,005,818
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Jak1
Janus kinase 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of JAK1 mRNA
CTD
PMID:17616710
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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Junb
JunB proto-oncogene, AP-1 transcription factor subunit
increases expression
ISO
phenethyl isothiocyanate results in increased expression of JUNB mRNA
CTD
PMID:26678675
NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035
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Kcnj12
potassium inwardly-rectifying channel, subfamily J, member 12
increases expression
EXP
phenethyl isothiocyanate results in increased expression of KCNJ12 mRNA
CTD
PMID:17616710
NCBI chr10:45,696,621...45,745,528
Ensembl chr10:45,696,849...45,745,492
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Kif18b
kinesin family member 18B
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of KIF18B mRNA
CTD
PMID:26678675
NCBI chr10:87,870,424...87,889,895
Ensembl chr10:87,870,428...87,889,850
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Kif20a
kinesin family member 20A
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of KIF20A mRNA
CTD
PMID:26678675
NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780
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Kif23
kinesin family member 23
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of KIF23 mRNA
CTD
PMID:26678675
NCBI chr 8:62,397,908...62,425,162
Ensembl chr 8:62,397,948...62,425,072
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Krt10
keratin 10
increases expression
EXP
phenethyl isothiocyanate results in increased expression of KRT10 mRNA
CTD
PMID:17616710
NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701
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Krt14
keratin 14
increases expression
EXP
phenethyl isothiocyanate results in increased expression of KRT14 protein
CTD
PMID:33211169
NCBI chr10:85,137,786...85,142,054
Ensembl chr10:85,066,802...85,171,799
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Krt16
keratin 16
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of KRT16 mRNA
CTD
PMID:17616710
NCBI chr10:85,168,357...85,171,816
Ensembl chr10:85,066,802...85,171,799
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Krtap14l
keratin associated protein 14 like
increases expression
EXP
phenethyl isothiocyanate results in increased expression of KRTAP14L mRNA
CTD
PMID:17616710
NCBI chr11:28,085,729...28,086,516
Ensembl chr11:28,086,010...28,086,516
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Ktn1
kinectin 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of KTN1 mRNA
CTD
PMID:17616710
NCBI chr15:20,913,665...21,002,588
Ensembl chr15:20,914,642...21,002,578
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Lars1
leucyl-tRNA synthetase 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of LARS1 mRNA
CTD
PMID:17616710
NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931
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Lig1
DNA ligase 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of LIG1 mRNA
CTD
PMID:26678675
NCBI chr 1:74,165,688...74,204,400
Ensembl chr 1:74,165,842...74,204,413
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Lima1
LIM domain and actin binding 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of LIMA1 mRNA
CTD
PMID:17616710
NCBI chr 7:130,901,717...131,001,512
Ensembl chr 7:130,901,717...131,001,473
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Lmnb1
lamin B1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of LMNB1 mRNA
CTD
PMID:26678675
NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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LOC120098354
small nucleolar RNA SNORD63
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SNORD63 mRNA
CTD
PMID:26678675
NCBI chr18:26,541,469...26,541,541
Ensembl chr18:26,541,469...26,541,541
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LOC120098679
small nucleolar RNA SNORA14
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SNORA14B mRNA
CTD
PMID:26678675
NCBI chr19:54,934,225...54,934,358
Ensembl chr19:54,934,225...54,934,358
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Lrr1
leucine rich repeat protein 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of LRR1 mRNA
CTD
PMID:26678675
NCBI chr 6:87,643,195...87,651,894
Ensembl chr 6:87,643,217...87,651,894
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Lrrc17
leucine rich repeat containing 17
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of LRRC17 mRNA
CTD
PMID:26678675
NCBI chr 4:13,501,428...13,531,845
Ensembl chr 4:13,501,436...13,531,845
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Lrrcc1
leucine rich repeat and coiled-coil centrosomal protein 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of LRRCC1 mRNA
CTD
PMID:17616710
NCBI chr 2:87,025,671...87,060,313
Ensembl chr 2:87,025,598...87,060,294
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Ly6k
lymphocyte antigen 6 family member K
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of LY6K mRNA
CTD
PMID:26678675
NCBI chr 7:106,683,749...106,712,802
Ensembl chr 7:106,683,753...106,686,372
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Lypd3
Ly6/Plaur domain containing 3
increases expression
EXP
phenethyl isothiocyanate results in increased expression of LYPD3 mRNA
CTD
PMID:17616710
NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901
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Map2
microtubule-associated protein 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of MAP2 mRNA
CTD
PMID:17616710
NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809
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Map4k3
mitogen-activated protein kinase kinase kinase kinase 3
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of MAP4K3 mRNA
CTD
PMID:17616710
NCBI chr 6:14,276,623...14,446,321
Ensembl chr 6:14,277,121...14,446,334
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Mapk1
mitogen activated protein kinase 1
multiple interactions
ISO
phenethyl isothiocyanate results in decreased phosphorylation of and results in decreased expression of MAPK1 protein
CTD
PMID:26456889
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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Mapk3
mitogen activated protein kinase 3
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of MAPK3 mRNA] phenethyl isothiocyanate results in decreased phosphorylation of and results in decreased expression of MAPK3 protein
CTD
PMID:20423518 PMID:26456889
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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Matn2
matrilin 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MATN2 mRNA
CTD
PMID:26678675
NCBI chr 7:65,494,996...65,644,613
Ensembl chr 7:65,494,834...65,645,113
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Matr3
matrin 3
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of MATR3 mRNA
CTD
PMID:17616710
NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166
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Mcl1
MCL1 apoptosis regulator, BCL2 family member
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MCL1 protein
CTD
PMID:16054126
NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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Mcm10
minichromosome maintenance 10 replication initiation factor
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MCM10 mRNA
CTD
PMID:26678675
NCBI chr17:73,263,788...73,288,346
Ensembl chr17:73,266,095...73,287,364
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Mcm2
minichromosome maintenance complex component 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MCM2 mRNA
CTD
PMID:26678675
NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
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Mcm5
minichromosome maintenance complex component 5
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MCM5 mRNA
CTD
PMID:26678675
NCBI chr19:13,483,030...13,504,389
Ensembl chr19:13,483,066...13,504,389
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Mcm7
minichromosome maintenance complex component 7
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MCM7 mRNA
CTD
PMID:26678675
NCBI chr12:17,042,207...17,049,470
Ensembl chr12:17,042,212...17,050,063
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Mcoln1
mucolipin TRP cation channel 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of MCOLN1 mRNA
CTD
PMID:17616710
NCBI chr12:1,560,341...1,574,252
Ensembl chr12:1,560,359...1,574,252
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Mipol1
mirror-image polydactyly 1
affects binding
ISO
MIPOL1 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 6:74,755,293...75,090,403
Ensembl chr 6:74,755,395...75,086,811
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Mki67
marker of proliferation Ki-67
decreases expression increases expression
EXP
phenethyl isothiocyanate results in decreased expression of MKI67 mRNA phenethyl isothiocyanate results in increased expression of MKI67 protein
CTD
PMID:17616710 PMID:23535288
NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
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Mmp7
matrix metallopeptidase 7
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of MMP7 mRNA]
CTD
PMID:23724058
NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
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Mmp9
matrix metallopeptidase 9
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]
CTD
PMID:23724058
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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Mnd1
meiotic nuclear divisions 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MND1 mRNA
CTD
PMID:26678675
NCBI chr 2:169,433,523...169,496,081
Ensembl chr 2:169,433,540...169,496,096
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Mns1
meiosis-specific nuclear structural 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MNS1 mRNA
CTD
PMID:26678675
NCBI chr 8:73,148,877...73,169,570
Ensembl chr 8:73,148,877...73,176,925
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Mpzl2
myelin protein zero-like 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MPZL2 mRNA
CTD
PMID:26678675
NCBI chr 8:45,348,285...45,359,298
Ensembl chr 8:45,348,285...45,359,298
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Mtf2
metal response element binding transcription factor 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of MTF2 mRNA
CTD
PMID:17616710
NCBI chr14:1,639,256...1,683,513
Ensembl chr14:1,640,746...1,683,524
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Mybl2
MYB proto-oncogene like 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MYBL2 mRNA
CTD
PMID:26678675
NCBI chr 3:151,705,254...151,733,714
Ensembl chr 3:151,705,288...151,733,708
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Myc
MYC proto-oncogene, bHLH transcription factor
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MYC mRNA; phenethyl isothiocyanate results in decreased expression of MYC protein
CTD
PMID:27579538
NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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Myl6
myosin light chain 6
affects binding
ISO
MYL6 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791
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Myo19
myosin XIX
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of MYO19 mRNA
CTD
PMID:26678675
NCBI chr10:69,753,082...69,782,450
Ensembl chr10:69,753,068...69,782,450
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Ncapg
non-SMC condensin I complex, subunit G
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of NCAPG mRNA
CTD
PMID:26678675
NCBI chr14:65,403,930...65,432,902
Ensembl chr14:65,404,163...65,432,902
G
Ncapg2
non-SMC condensin II complex, subunit G2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of NCAPG2 mRNA
CTD
PMID:26678675
NCBI chr 6:137,342,449...137,418,083
Ensembl chr 6:137,342,943...137,415,159
G
Ncaph
non-SMC condensin I complex, subunit H
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of NCAPH mRNA
CTD
PMID:26678675
NCBI chr 3:114,371,937...114,399,178
Ensembl chr 3:114,371,941...114,399,180
G
Ncor1
nuclear receptor co-repressor 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of NCOR1 mRNA
CTD
PMID:17616710
NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
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Ndrg1
N-myc downstream regulated 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of NDRG1 mRNA
CTD
PMID:17937621
NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
G
Ndufa2
NADH:ubiquinone oxidoreductase subunit A2
affects binding
ISO
NDUFA2 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr18:28,355,774...28,357,863
Ensembl chr18:28,355,774...28,358,076
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Nek9
NIMA-related kinase 9
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of NEK9 mRNA
CTD
PMID:17616710
NCBI chr 6:104,944,056...104,984,538
Ensembl chr 6:104,944,056...104,984,538
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Net1
neuroepithelial cell transforming 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of NET1 mRNA
CTD
PMID:17616710
NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441
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Nfe2l2
NFE2 like bZIP transcription factor 2
affects localization multiple interactions increases expression increases activity
ISO EXP
phenethyl isothiocyanate affects the localization of NFE2L2 protein NFE2L2 gene mutant form affects the reaction [phenethyl isothiocyanate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 protein]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of IL6 protein]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of HMOX1 mRNA]]; NFE2L2 protein affects the reaction [phenethyl isothiocyanate results in increased expression of CYP2A5 mRNA]; NFE2L2 protein results in increased susceptibility to [lipopolysaccharide, Escherichia coli O111 B4 co-treated with phenethyl isothiocyanate] phenethyl isothiocyanate results in increased expression of NFE2L2 protein [indole-3-carbinol co-treated with phenethyl isothiocyanate] results in increased expression of NFE2L2 mRNA; [Resveratrol co-treated with phenethyl isothiocyanate] results in increased expression of NFE2L2 mRNA; [xanthohumol co-treated with phenethyl isothiocyanate] results in increased activity of NFE2L2 protein; [xanthohumol co-treated with phenethyl isothiocyanate] results in increased expression of and results in increased activity of NFE2L2 protein; [xanthohumol co-treated with phenethyl isothiocyanate] results in increased expression of NFE2L2 mRNA; Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]; diphenyleneiodonium inhibits the reaction [phenethyl isothiocyanate affects the localization of NFE2L2 protein]; ferrous sulfate inhibits the reaction [Deferoxamine inhibits the reaction [phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein]]; phenethyl isothiocyanate results in increased expression of and affects the localization of NFE2L2 protein phenethyl isothiocyanate results in increased expression of NFE2L2 mRNA; phenethyl isothiocyanate results in increased expression of NFE2L2 protein phenethyl isothiocyanate results in increased activity of NFE2L2 protein
CTD
PMID:20402460 PMID:22664424 PMID:25246272 PMID:25387343 PMID:26945724 PMID:32070777 More...
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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Nfkb1
nuclear factor kappa B subunit 1
multiple interactions decreases expression
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 mRNA] [indole-3-carbinol co-treated with phenethyl isothiocyanate] results in decreased expression of NFKB1 mRNA; [xanthohumol co-treated with phenethyl isothiocyanate] results in decreased expression of and results in decreased activity of NFKB1 protein; [xanthohumol co-treated with phenethyl isothiocyanate] results in decreased expression of NFKB1 mRNA; phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB1 mRNA]; phenethyl isothiocyanate results in decreased expression of and results in decreased activity of NFKB1 protein phenethyl isothiocyanate results in decreased expression of NFKB1 mRNA
CTD
PMID:20423518 PMID:23724058 PMID:32070777
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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Nfkb2
nuclear factor kappa B subunit 2
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKB2 mRNA]
CTD
PMID:20423518
NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213
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Nfkbia
NFKB inhibitor alpha
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of NFKBIA mRNA]
CTD
PMID:20423518 PMID:23724058
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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Nme1
NME/NM23 nucleoside diphosphate kinase 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of NME1 mRNA
CTD
PMID:17616710
NCBI chr10:78,907,036...78,929,659
Ensembl chr10:78,906,083...78,916,408
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Nop53
NOP53 ribosome biogenesis factor
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of NOP53 mRNA
CTD
PMID:17616710
NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902
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Nos2
nitric oxide synthase 2
decreases expression multiple interactions
ISO
phenethyl isothiocyanate results in decreased expression of NOS2 mRNA phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of NOS2 mRNA]; phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased activity of NOS2 protein]
CTD
PMID:12628514 PMID:16373530 PMID:25387343
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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Notch1
notch receptor 1
multiple interactions increases expression
ISO
N-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [phenethyl isothiocyanate results in increased cleavage of and results in increased activity of NOTCH1 protein]; phenethyl isothiocyanate results in increased cleavage of and results in increased activity of NOTCH1 protein phenethyl isothiocyanate results in increased expression of NOTCH1 mRNA
CTD
PMID:22039516
NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531
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Notch2
notch receptor 2
increases expression multiple interactions increases response to substance
ISO
phenethyl isothiocyanate results in increased expression of NOTCH2 mRNA phenethyl isothiocyanate results in increased cleavage of and results in increased activity of and results in increased localization of NOTCH2 protein NOTCH2 protein results in increased susceptibility to phenethyl isothiocyanate
CTD
PMID:22039516
NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088
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Npc1l1
NPC1 like intracellular cholesterol transporter 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of NPC1L1 mRNA
CTD
PMID:17616710
NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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Nqo1
NAD(P)H quinone dehydrogenase 1
increases expression increases activity multiple interactions
ISO EXP
phenethyl isothiocyanate results in increased expression of NQO1 mRNA; phenethyl isothiocyanate results in increased expression of NQO1 protein phenethyl isothiocyanate results in increased activity of NQO1 protein [indole-3-carbinol co-treated with phenethyl isothiocyanate] results in increased expression of NQO1 mRNA; [phenethyl isothiocyanate co-treated with Resveratrol] results in increased expression of NQO1 mRNA; [phenethyl isothiocyanate co-treated with xanthohumol] results in increased expression of NQO1 mRNA; [xanthohumol co-treated with phenethyl isothiocyanate] results in increased expression of NQO1 protein
CTD
PMID:12628514 PMID:15672752 PMID:20442190 PMID:22664424 PMID:32070777
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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Nr2f2
nuclear receptor subfamily 2, group F, member 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of NR2F2 mRNA
CTD
PMID:26678675
NCBI chr 1:124,008,282...124,022,521
Ensembl chr 1:124,009,181...124,022,031
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Nrm
nurim
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of NRM mRNA
CTD
PMID:26678675
NCBI chr20:2,888,321...2,892,804
Ensembl chr20:2,877,567...2,891,802
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Nrtn
neurturin
increases expression
EXP
phenethyl isothiocyanate results in increased expression of NRTN mRNA
CTD
PMID:17616710
NCBI chr 9:1,581,860...1,587,835
Ensembl chr 9:1,581,975...1,583,102
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Nudc
nuclear distribution C, dynein complex regulator
affects binding
ISO
NUDC protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 5:145,758,006...145,771,390
Ensembl chr 5:145,758,002...145,771,425
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Odc1
ornithine decarboxylase 1
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of ODC1 protein]
CTD
PMID:12628514
NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440
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Or1f19f
olfactory receptor family 1 subfamily F member 19F
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of OR1F19F mRNA
CTD
PMID:17616710
NCBI chr10:12,227,446...12,232,048
Ensembl chr10:12,231,119...12,232,048
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Or51b6b
olfactory receptor family 51 subfamily B member 6B
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of OR51B5 mRNA
CTD
PMID:26678675
NCBI chr 1:158,072,748...158,073,701
Ensembl chr 1:158,072,748...158,073,701
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Or52z1
olfactory receptor family 52 subfamily Z member 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of OR52Z1 mRNA
CTD
PMID:17616710
NCBI chr 1:158,206,284...158,207,246
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Oxtr
oxytocin receptor
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of OXTR mRNA
CTD
PMID:26678675
NCBI chr 4:145,598,549...145,614,674
Ensembl chr 4:145,599,561...145,614,674
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Pabpc4
poly(A) binding protein, cytoplasmic 4
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of PABPC4 mRNA
CTD
PMID:17616710
NCBI chr 5:135,563,142...135,578,985
Ensembl chr 5:135,563,562...135,578,979
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Pappa
pappalysin
affects binding
ISO
PAPPA protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
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Parp1
poly (ADP-ribose) polymerase 1
multiple interactions increases cleavage
ISO
Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased cleavage of PARP1 protein]
CTD
PMID:25246272
NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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Parp8
poly (ADP-ribose) polymerase family, member 8
increases expression
ISO
phenethyl isothiocyanate results in increased expression of PARP8 mRNA
CTD
PMID:26678675
NCBI chr 2:48,679,405...48,848,700
Ensembl chr 2:48,679,436...48,849,253
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Pbk
PDZ binding kinase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PBK mRNA
CTD
PMID:26678675
NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
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Pclaf
PCNA clamp associated factor
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PCLAF mRNA
CTD
PMID:26678675
NCBI chr 8:66,420,606...66,432,994
Ensembl chr 8:66,420,587...66,432,994 Ensembl chr 8:66,420,587...66,432,994
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Pcm1
pericentriolar material 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of PCM1 mRNA
CTD
PMID:17616710
NCBI chr16:51,008,315...51,105,261
Ensembl chr16:51,008,315...51,105,091
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Pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of PCMTD1 mRNA
CTD
PMID:26678675
NCBI chr 5:12,284,711...12,355,680
Ensembl chr 5:12,284,711...12,354,899
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Pdcl3
phosducin-like 3
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PDCL3 mRNA
CTD
PMID:26678675
NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
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Per3
period circadian regulator 3
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PER3 mRNA
CTD
PMID:26678675
NCBI chr 5:161,460,228...161,495,404
Ensembl chr 5:161,459,533...161,495,607
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Phf19
PHD finger protein 19
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PHF19 mRNA
CTD
PMID:26678675
NCBI chr 3:18,175,281...18,197,289
Ensembl chr 3:18,175,282...18,196,405
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Plac8
placenta associated 8
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PLAC8 mRNA
CTD
PMID:26678675
NCBI chr14:9,052,601...9,074,264
Ensembl chr14:9,063,048...9,074,264
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Plekha7
pleckstrin homology domain containing A7
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PLEKHA7 mRNA
CTD
PMID:26678675
NCBI chr 1:170,364,524...170,547,843
Ensembl chr 1:170,365,135...170,547,775
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Plekhh2
pleckstrin homology, MyTH4 and FERM domain containing H2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of PLEKHH2 mRNA
CTD
PMID:17616710
NCBI chr 6:10,032,837...10,132,081
Ensembl chr 6:10,032,660...10,140,794
G
Plk1
polo-like kinase 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PLK1 mRNA
CTD
PMID:26678675
NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400
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Plk4
polo-like kinase 4
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PLK4 mRNA
CTD
PMID:26678675
NCBI chr 2:123,802,527...123,820,942
Ensembl chr 2:123,802,512...123,820,942
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Pof1b
POF1B, actin binding protein
increases expression
EXP
phenethyl isothiocyanate results in increased expression of POF1B mRNA
CTD
PMID:17616710
NCBI chr X:77,683,128...77,749,827
Ensembl chr X:77,683,128...77,749,688
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Pola1
DNA polymerase alpha 1, catalytic subunit
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of POLA1 mRNA
CTD
PMID:26678675
NCBI chr X:58,034,617...58,348,612
Ensembl chr X:58,034,619...58,348,536
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Pola2
DNA polymerase alpha 2, accessory subunit
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of POLA2 mRNA
CTD
PMID:26678675
NCBI chr 1:203,227,183...203,251,350
Ensembl chr 1:203,203,388...203,251,348
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Pold1
DNA polymerase delta 1, catalytic subunit
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of POLD1 mRNA
CTD
PMID:26678675
NCBI chr 1:95,025,462...95,041,559
Ensembl chr 1:95,025,499...95,036,465
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Pole
DNA polymerase epsilon, catalytic subunit
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of POLE mRNA
CTD
PMID:26678675
NCBI chr12:46,345,420...46,393,984
Ensembl chr12:46,345,420...46,393,939
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Pole2
DNA polymerase epsilon 2, accessory subunit
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of POLE2 mRNA
CTD
PMID:26678675
NCBI chr 6:87,674,702...87,712,723
Ensembl chr 6:87,674,702...87,699,305
G
Ppih
peptidylprolyl isomerase H
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of PPIH mRNA
CTD
PMID:17616710
NCBI chr 5:132,906,324...132,924,341
Ensembl chr 5:132,906,328...132,924,267
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Ppil4
peptidylprolyl isomerase like 4
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of PPIL4 mRNA
CTD
PMID:17616710
NCBI chr 1:2,273,582...2,305,639
Ensembl chr 1:2,273,609...2,305,632
G
Ppp1r12a
protein phosphatase 1, regulatory subunit 12A
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of PPP1R12A mRNA
CTD
PMID:17616710
NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
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Prim1
DNA primase subunit 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of PRIM1 mRNA
CTD
PMID:26678675
NCBI chr 7:446,342...462,526
Ensembl chr 7:431,805...462,526
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Prkab2
protein kinase AMP-activated non-catalytic subunit beta 2
increases expression
ISO
phenethyl isothiocyanate results in increased expression of PRKAB2 mRNA
CTD
PMID:26678675
NCBI chr 2:185,257,218...185,272,846
Ensembl chr 2:185,257,213...185,269,872
G
Prkca
protein kinase C, alpha
multiple interactions
ISO
phenethyl isothiocyanate results in decreased phosphorylation of and results in decreased expression of PRKCA protein
CTD
PMID:26456889
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
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Prkcb
protein kinase C, beta
multiple interactions
ISO
phenethyl isothiocyanate results in decreased phosphorylation of and results in decreased expression of PRKCB protein
CTD
PMID:26456889
NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536
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Prkcz
protein kinase C, zeta
multiple interactions
ISO
phenethyl isothiocyanate results in decreased phosphorylation of and results in decreased expression of PRKCZ protein
CTD
PMID:26456889
NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367
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Pros1
protein S
increases expression
ISO
phenethyl isothiocyanate results in increased expression of PROS1 mRNA
CTD
PMID:26678675
NCBI chr11:230,597...311,288
Ensembl chr11:230,696...311,286
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Psma3
proteasome 20S subunit alpha 3
affects binding
ISO
PSMA3 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 6:89,483,741...89,503,775
Ensembl chr 6:89,483,727...89,504,965
G
Psmb3
proteasome 20S subunit beta 3
increases expression
EXP
phenethyl isothiocyanate results in increased expression of PSMB3 mRNA
CTD
PMID:17616710
NCBI chr10:82,697,425...82,704,521
Ensembl chr10:82,697,425...82,704,521
G
Psmc3
proteasome 26S subunit, ATPase 3
affects binding
ISO
PSMC3 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 3:77,031,825...77,037,207
Ensembl chr 3:77,031,825...77,043,358
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Ptgs2
prostaglandin-endoperoxide synthase 2
decreases expression multiple interactions
ISO
phenethyl isothiocyanate results in decreased expression of PTGS2 mRNA NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]]; phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein] [phenethyl isothiocyanate co-treated with indole-3-carbinol] results in decreased expression of PTGS2 mRNA; [xanthohumol co-treated with phenethyl isothiocyanate] results in decreased expression of PTGS2 mRNA; [xanthohumol co-treated with phenethyl isothiocyanate] results in decreased expression of PTGS2 protein
CTD
PMID:16373530 PMID:25387343 PMID:32070777
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Ptpre
protein tyrosine phosphatase, receptor type, E
increases expression
EXP
phenethyl isothiocyanate results in increased expression of PTPRE mRNA
CTD
PMID:17616710
NCBI chr 1:190,344,331...190,494,815
Ensembl chr 1:190,344,401...190,489,534
G
Pwwp2a
PWWP domain containing 2A
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of PWWP2A mRNA
CTD
PMID:17616710
NCBI chr10:28,155,509...28,195,255
Ensembl chr10:28,155,605...28,194,308
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Qsox1
quiescin sulfhydryl oxidase 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of QSOX1 mRNA
CTD
PMID:17616710
NCBI chr13:67,949,780...67,987,434
Ensembl chr13:67,949,780...67,987,459
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Rab11a
RAB11a, member RAS oncogene family
increases expression
EXP
phenethyl isothiocyanate results in increased expression of RAB11A mRNA
CTD
PMID:17616710
NCBI chr 8:65,223,698...65,246,461
Ensembl chr 8:65,222,949...65,246,525
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Rab15
RAB15, member RAS oncogene family
affects binding
ISO
RAB15 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 6:95,499,584...95,524,073
Ensembl chr 6:95,499,587...95,523,942
G
Rad51
RAD51 recombinase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of RAD51 mRNA
CTD
PMID:26678675
NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
G
Raf1
Raf-1 proto-oncogene, serine/threonine kinase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of RAF1 protein
CTD
PMID:26456889
NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
G
Ranbp1
RAN binding protein 1
affects binding
ISO
RANBP1 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr11:82,742,603...82,750,836
Ensembl chr11:82,742,600...82,750,838
G
Rap1b
RAP1B, member of RAS oncogene family
increases expression
EXP
phenethyl isothiocyanate results in increased expression of RAP1B mRNA
CTD
PMID:17616710
NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370
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Rasa1
RAS p21 protein activator 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of RASA1 mRNA
CTD
PMID:17616710
NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854
G
Rbbp6
RB binding protein 6, ubiquitin ligase
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of RBBP6 mRNA
CTD
PMID:17616710
NCBI chr 1:177,503,988...177,537,397
Ensembl chr 1:177,503,313...177,535,678
G
Rec114
REC114 meiotic recombination protein
increases expression
EXP
phenethyl isothiocyanate results in increased expression of REC114 mRNA
CTD
PMID:17616710
NCBI chr 8:59,063,352...59,221,439
Ensembl chr 8:59,063,352...59,149,887
G
Reep5
receptor accessory protein 5
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of REEP5 mRNA
CTD
PMID:17616710
NCBI chr18:25,945,375...25,983,271
Ensembl chr18:25,945,381...25,976,509
G
Rel
REL proto-oncogene, NF-kB subunit
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of REL mRNA]
CTD
PMID:20423518 PMID:23724058
NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
G
Rela
RELA proto-oncogene, NF-kB subunit
multiple interactions decreases expression
ISO
[indole-3-carbinol co-treated with phenethyl isothiocyanate] results in decreased activity of RELA protein; [indole-3-carbinol co-treated with phenethyl isothiocyanate] results in decreased expression of RELA mRNA; [phenethyl isothiocyanate co-treated with Resveratrol] results in decreased expression of RELA mRNA; [phenethyl isothiocyanate co-treated with xanthohumol] results in decreased expression of and results in decreased activity of RELA protein; [phenethyl isothiocyanate co-treated with xanthohumol] results in decreased expression of RELA mRNA; [Resveratrol co-treated with phenethyl isothiocyanate] results in decreased activity of RELA protein; phenethyl isothiocyanate results in decreased expression of and results in decreased activity of RELA protein phenethyl isothiocyanate results in decreased expression of RELA mRNA
CTD
PMID:32070777
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
G
Relb
RELB proto-oncogene, NF-kB subunit
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of RELB mRNA]
CTD
PMID:20423518 PMID:23724058
NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
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Ripk2
receptor-interacting serine-threonine kinase 2
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of RIPK2 mRNA]
CTD
PMID:20423518
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
G
Rnf39
ring finger protein 39
increases expression
EXP
phenethyl isothiocyanate results in increased expression of RNF39 mRNA
CTD
PMID:17616710
NCBI chr20:1,604,794...1,610,283
Ensembl chr20:1,604,794...1,610,283
G
Rock1
Rho-associated coiled-coil containing protein kinase 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ROCK1 mRNA
CTD
PMID:17616710
NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571
G
Rock2
Rho-associated coiled-coil containing protein kinase 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ROCK2 mRNA
CTD
PMID:17616710
NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
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Rpl3
ribosomal protein L3
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of RPL3 mRNA
CTD
PMID:17616710
NCBI chr 7:111,622,255...111,627,640
Ensembl chr 7:111,621,610...111,636,468
G
Rpl5
ribosomal protein L5
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of RPL5 mRNA
CTD
PMID:17616710
NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
G
Rplp2
ribosomal protein lateral stalk subunit P2
affects binding
ISO
RPLP2 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 1:196,546,086...196,548,636
Ensembl chr 1:196,546,352...196,548,645
G
Rps21-ps1
ribosomal protein S21, pseudogene 1
affects binding
ISO
RPS21 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 5:153,387,133...153,387,476
Ensembl chr 5:153,387,176...153,387,427
G
Rps6kb1
ribosomal protein S6 kinase B1
decreases phosphorylation
ISO
phenethyl isothiocyanate results in decreased phosphorylation of RPS6KB1 protein
CTD
PMID:27579538
NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
G
Rsph3
radial spoke head 3
increases expression
ISO
phenethyl isothiocyanate results in increased expression of RSPH3 mRNA
CTD
PMID:26678675
NCBI chr 1:47,101,961...47,155,201
Ensembl chr 1:47,101,961...47,154,232
G
Rtkn2
rhotekin 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of RTKN2 mRNA
CTD
PMID:26678675
NCBI chr20:20,536,628...20,609,951
Ensembl chr20:20,525,256...20,609,951
G
S100a10
S100 calcium binding protein A10
affects binding
ISO
S100A10 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661
G
S100a7l2
S100 calcium binding protein A7 like 2
increases expression
EXP
phenethyl isothiocyanate results in increased expression of S100A7L2 mRNA
CTD
PMID:17616710
NCBI chr 2:176,506,300...176,509,196
Ensembl chr 2:176,506,300...176,509,196 Ensembl chr 2:176,506,300...176,509,196
G
Safb
scaffold attachment factor B
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SAFB mRNA
CTD
PMID:17616710
NCBI chr 9:1,417,449...1,438,408
Ensembl chr 9:1,417,525...1,438,644
G
Sat1
spermidine/spermine N1-acetyl transferase 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SAT1 mRNA
CTD
PMID:26678675
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
G
Sbno1
strawberry notch homolog 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SBNO1 mRNA
CTD
PMID:17616710
NCBI chr12:32,175,176...32,234,200
Ensembl chr12:32,185,485...32,230,158
G
Scarna7
small Cajal body-specific RNA 7
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SCARNA7 mRNA
CTD
PMID:26678675
NCBI chr 2:153,336,855...153,337,181
Ensembl chr 2:153,336,855...153,337,181
G
Scd
stearoyl-CoA desaturase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of SCD mRNA
CTD
PMID:26678675
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
G
Sdhaf1
succinate dehydrogenase complex assembly factor 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SDHAF1 mRNA
CTD
PMID:17616710
NCBI chr 1:85,576,207...85,577,156
Ensembl chr 1:85,576,041...85,577,366 Ensembl chr 1:85,576,041...85,577,366
G
Sec16a
SEC16 homolog A, endoplasmic reticulum export factor
increases expression
EXP
phenethyl isothiocyanate results in increased expression of SEC16A mRNA
CTD
PMID:17616710
NCBI chr 3:9,229,687...9,264,837
Ensembl chr 3:9,229,687...9,264,273
G
Selenbp1
selenium binding protein 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SELENBP1 mRNA
CTD
PMID:17616710
NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594
G
Sephs1
selenophosphate synthetase 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of SEPHS1 mRNA
CTD
PMID:26678675
NCBI chr17:73,354,435...73,382,803
Ensembl chr17:73,356,530...73,382,593
G
Serpinb12
serpin family B member 12
increases expression
EXP
phenethyl isothiocyanate results in increased expression of SERPINB12 mRNA
CTD
PMID:17616710
NCBI chr13:23,052,384...23,083,691
Ensembl chr13:23,052,448...23,083,691
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Serpine1
serpin family E member 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SERPINE1 mRNA
CTD
PMID:26678675
NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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Serpini1
serpin family I member 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SERPINI1 mRNA
CTD
PMID:26678675
NCBI chr 2:160,346,403...160,433,135
Ensembl chr 2:160,346,758...160,433,135
G
Sf3a3
splicing factor 3a, subunit 3
affects binding
ISO
SF3A3 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 5:136,967,713...136,987,345
Ensembl chr 5:136,967,691...136,987,361
G
Sf3b2
splicing factor 3b, subunit 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SF3B2 mRNA
CTD
PMID:17616710
NCBI chr 1:202,570,423...202,590,774
Ensembl chr 1:202,570,423...202,590,759
G
Shcbp1
SHC binding and spindle associated 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of SHCBP1 mRNA
CTD
PMID:26678675
NCBI chr16:84,672,277...84,703,843
Ensembl chr16:84,672,321...84,703,844
G
Ska2
spindle and kinetochore associated complex subunit 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of SKA2 mRNA
CTD
PMID:26678675
NCBI chr10:71,921,474...71,939,461
Ensembl chr10:71,921,582...71,939,458
G
Ska3
spindle and kinetochore associated complex subunit 3
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of SKA3 mRNA
CTD
PMID:26678675
NCBI chr15:31,951,812...31,971,010
Ensembl chr15:31,951,825...31,971,010
G
Skp2
S-phase kinase associated protein 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of SKP2 mRNA
CTD
PMID:26678675
NCBI chr 2:58,161,226...58,189,293
Ensembl chr 2:58,161,229...58,189,338
G
Slc12a2
solute carrier family 12 member 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SLC12A2 mRNA
CTD
PMID:17616710
NCBI chr18:51,348,282...51,416,448
Ensembl chr18:51,348,302...51,416,440
G
Slc20a1
solute carrier family 20 member 1
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of SLC20A1 mRNA]
CTD
PMID:20423518
NCBI chr 3:116,427,095...116,441,049
Ensembl chr 3:116,427,098...116,441,051
G
Slc20a2
solute carrier family 20 member 2
increases expression
EXP
phenethyl isothiocyanate results in increased expression of SLC20A2 mRNA
CTD
PMID:17616710
NCBI chr16:69,460,850...69,551,418
Ensembl chr16:69,460,462...69,521,711
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Slfn5
schlafen family member 5
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SLFN5 mRNA
CTD
PMID:26678675
NCBI chr10:67,881,068...67,895,013
Ensembl chr10:67,880,009...67,893,109
G
Slurp1
secreted Ly6/Plaur domain containing 1
increases expression
EXP
phenethyl isothiocyanate results in increased expression of SLURP1 mRNA
CTD
PMID:17616710
NCBI chr 7:106,611,949...106,613,365
Ensembl chr 7:106,611,949...106,613,365
G
Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
affects binding
ISO
SMARCE1 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr10:84,159,270...84,180,547
Ensembl chr10:84,159,275...84,179,989
G
Smc3
structural maintenance of chromosomes 3
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SMC3 mRNA
CTD
PMID:17616710
NCBI chr 1:252,601,422...252,644,522
Ensembl chr 1:252,601,753...252,644,522
G
Smpd1
sphingomyelin phosphodiesterase 1
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SMPD1 mRNA
CTD
PMID:26678675
NCBI chr 1:159,892,946...159,896,789
Ensembl chr 1:159,892,859...159,896,794
G
Smurf2
SMAD specific E3 ubiquitin protein ligase 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SMURF2 mRNA
CTD
PMID:17616710
NCBI chr10:91,761,798...91,862,485
Ensembl chr10:91,761,807...91,862,488
G
Spsb3
splA/ryanodine receptor domain and SOCS box containing 3
increases expression
EXP
phenethyl isothiocyanate results in increased expression of SPSB3 mRNA
CTD
PMID:17616710
NCBI chr10:13,907,175...13,912,841
Ensembl chr10:13,907,253...13,912,841
G
Srrm1
serine and arginine repetitive matrix 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of SRRM1 mRNA
CTD
PMID:17616710
NCBI chr 5:147,559,515...147,591,895
Ensembl chr 5:147,559,514...147,591,849
G
Stat1
signal transducer and activator of transcription 1
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of and results in increased phosphorylation of STAT1 protein]; phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA] phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 mRNA]; phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of STAT1 protein]
CTD
PMID:20423518 PMID:23724058
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
G
Suclg2
succinate-CoA ligase GDP-forming subunit beta
affects binding
ISO
SUCLG2 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 4:128,067,031...128,337,146
Ensembl chr 4:128,067,033...128,337,170
G
Suv39h1
SUV39H1 histone lysine methyltransferase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of SUV39H1 mRNA
CTD
PMID:26678675
NCBI chr X:14,421,028...14,433,993
Ensembl chr X:14,421,109...14,433,982
G
Suv39h1-ps1
SUV39H1 histone lysine methyltransferase, pseudogene 1
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of SUV39H1 mRNA
CTD
PMID:26678675
NCBI chr X:141,792,589...141,795,257
G
Swt1
SWT1 RNA endoribonuclease homolog
increases expression
ISO
phenethyl isothiocyanate results in increased expression of SWT1 mRNA
CTD
PMID:26678675
NCBI chr13:63,452,494...63,509,982
Ensembl chr13:63,452,496...63,509,980
G
Tagln3
transgelin 3
increases expression
ISO
phenethyl isothiocyanate results in increased expression of TAGLN3 mRNA
CTD
PMID:26678675
NCBI chr11:55,099,887...55,113,457
Ensembl chr11:55,099,743...55,113,485
G
Tcf12
transcription factor 12
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of TCF12 mRNA
CTD
PMID:17616710
NCBI chr 8:72,490,447...72,799,265
Ensembl chr 8:72,492,567...72,799,201
G
Tcp11l2
t-complex 11 like 2
increases expression
ISO
phenethyl isothiocyanate results in increased expression of TCP11L2 mRNA
CTD
PMID:26678675
NCBI chr 7:19,150,241...19,185,135
Ensembl chr 7:19,150,252...19,185,095
G
Tfr2
transferrin receptor 2
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of TFR2 mRNA
CTD
PMID:26678675
NCBI chr12:19,107,673...19,124,622
Ensembl chr12:19,107,673...19,124,591
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Thoc2
THO complex subunit 2
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of THOC2 mRNA
CTD
PMID:17616710
NCBI chr X:120,634,966...120,749,569
Ensembl chr X:120,634,968...120,749,513
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Timeless
timeless circadian regulator
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of TIMELESS mRNA
CTD
PMID:26678675
NCBI chr 7:654,804...678,769
Ensembl chr 7:654,822...678,738
G
Tmem229b
transmembrane protein 229B
increases expression
EXP
phenethyl isothiocyanate results in increased expression of TMEM229B mRNA
CTD
PMID:17616710
NCBI chr 6:97,771,645...97,819,582
Ensembl chr 6:97,775,332...97,819,489
G
Tmem97
transmembrane protein 97
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of TMEM97 mRNA
CTD
PMID:26678675
NCBI chr10:63,438,228...63,447,311
Ensembl chr10:63,438,222...63,589,730
G
Tmpo
thymopoietin
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of TMPO mRNA
CTD
PMID:17616710
NCBI chr 7:25,642,752...25,667,756
Ensembl chr 7:25,586,725...25,667,727
G
Tnf
tumor necrosis factor
multiple interactions
ISO EXP
NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]]; NFE2L2 gene mutant form inhibits the reaction [phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein]]; phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of TNF mRNA]; phenethyl isothiocyanate inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of TNF protein] phenethyl isothiocyanate inhibits the reaction [Freund's Adjuvant results in increased expression of TNF protein]
CTD
PMID:25387343 PMID:32289289
NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
G
Tnfaip3
TNF alpha induced protein 3
multiple interactions
ISO
phenethyl isothiocyanate inhibits the reaction [Lipopolysaccharides results in increased expression of TNFAIP3 mRNA]
CTD
PMID:20423518 PMID:23724058
NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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Tp53
tumor protein p53
increases expression
ISO
phenethyl isothiocyanate results in increased expression of TP53 protein
CTD
PMID:16054126
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
G
Tpd52l2
TPD52 like 2
affects binding
ISO
TPD52L2 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 3:168,598,449...168,618,201
Ensembl chr 3:168,594,609...168,619,762
G
Tpm1
tropomyosin 1
affects binding
ISO
TPM1 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
G
Tpm3
tropomyosin 3
affects binding
ISO
TPM3 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013
G
Tpm4
tropomyosin 4
affects binding
ISO
TPM4 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
G
Tpr
translocated promoter region, nuclear basket protein
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of TPR mRNA
CTD
PMID:17616710
NCBI chr13:62,424,312...62,487,502
Ensembl chr13:62,424,312...62,487,496
G
Trip13
thyroid hormone receptor interactor 13
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of TRIP13 mRNA
CTD
PMID:26678675
NCBI chr 1:29,357,093...29,402,078
Ensembl chr 1:29,357,130...29,402,074
G
Ttc14
tetratricopeptide repeat domain 14
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of TTC14 mRNA
CTD
PMID:17616710
NCBI chr 2:116,653,543...116,665,072
Ensembl chr 2:116,653,595...116,664,158
G
Tuba1a
tubulin, alpha 1A
affects binding
ISO
TUBA1A protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186
G
Tuba3b
tubulin, alpha 3B
affects binding
ISO
TUBA3D protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 4:178,588,779...178,594,328
Ensembl chr 4:178,588,779...178,594,326
G
Tuba4a
tubulin, alpha 4A
increases expression affects binding
EXP ISO
phenethyl isothiocyanate results in increased expression of TUBA4A mRNA TUBA4A protein binds to phenethyl isothiocyanate
CTD
PMID:17616710 PMID:21838287
NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
G
Tubb1
tubulin, beta 1 class VI
affects binding
ISO
TUBB1 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 3:163,247,990...163,257,460
Ensembl chr 3:163,247,967...163,256,063
G
Tubb2a
tubulin, beta 2A class IIa
affects binding
ISO
TUBB2A protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
G
Tubb3
tubulin, beta 3 class III
affects binding
ISO
TUBB3 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243
G
Tubb4b
tubulin, beta 4B class IVb
affects binding
ISO
TUBB4B protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296
G
Txn1
thioredoxin 1
increases expression affects binding
ISO EXP
phenethyl isothiocyanate results in increased expression of TXN mRNA phenethyl isothiocyanate results in increased expression of TXN1 mRNA TXN protein binds to phenethyl isothiocyanate
CTD
PMID:17616710 PMID:20442190 PMID:21838287
NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629
G
Txnip
thioredoxin interacting protein
increases expression
ISO
phenethyl isothiocyanate results in increased expression of TXNIP mRNA
CTD
PMID:26678675
NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886
G
Txnrd1
thioredoxin reductase 1
decreases activity increases expression
ISO EXP
phenethyl isothiocyanate results in decreased activity of TXNRD1 protein phenethyl isothiocyanate results in increased expression of TXNRD1 mRNA
CTD
PMID:17616710 PMID:17937621 PMID:20442190
NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
G
Ubtf
upstream binding transcription factor
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of UBTF mRNA
CTD
PMID:17616710
NCBI chr10:87,258,217...87,274,291
Ensembl chr10:87,258,217...87,272,969
G
Uchl1
ubiquitin C-terminal hydrolase L1
affects binding
ISO
UCHL1 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
G
Ugt1a6
UDP glucuronosyltransferase family 1 member A6
increases expression
EXP
phenethyl isothiocyanate results in increased expression of UGT1A6 protein
CTD
PMID:21132492
NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465
G
Unc5b
unc-5 netrin receptor B
increases expression
ISO
phenethyl isothiocyanate results in increased expression of UNC5B mRNA
CTD
PMID:26678675
NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537
G
Ung
uracil-DNA glycosylase
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of UNG mRNA
CTD
PMID:26678675
NCBI chr12:42,485,276...42,494,217
Ensembl chr12:42,485,276...42,494,206
G
Usp14
ubiquitin specific peptidase 14
affects binding
ISO
USP14 protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
G
Usp7
ubiquitin specific peptidase 7
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of USP7 mRNA
CTD
PMID:17616710
NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355
G
Vcp
valosin-containing protein
affects binding
ISO
VCP protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 5:57,210,167...57,229,571
Ensembl chr 5:57,210,168...57,229,571
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Vezf1
vascular endothelial zinc finger 1
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of VEZF1 mRNA
CTD
PMID:17616710
NCBI chr10:72,859,669...72,876,111
Ensembl chr10:72,859,877...72,876,111
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Vim
vimentin
affects binding
ISO
VIM protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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Wdr76
WD repeat domain 76
decreases expression
ISO
phenethyl isothiocyanate results in decreased expression of WDR76 mRNA
CTD
PMID:26678675
NCBI chr 3:108,456,784...108,491,528
Ensembl chr 3:108,456,815...108,490,840
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Xiap
X-linked inhibitor of apoptosis
multiple interactions decreases expression
ISO
benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [phenethyl isothiocyanate results in decreased expression of XIAP protein]; Vitamin E inhibits the reaction [phenethyl isothiocyanate results in decreased expression of XIAP protein]
CTD
PMID:16054126
NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
G
Ypel2
yippee-like 2
increases expression
ISO
phenethyl isothiocyanate results in increased expression of YPEL2 mRNA
CTD
PMID:26678675
NCBI chr10:71,746,308...71,803,843
Ensembl chr10:71,746,311...71,803,911
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Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
affects binding
ISO
YWHAB protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
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Ywhae
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
affects binding
ISO
YWHAE protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr10:60,584,665...60,622,352
Ensembl chr10:60,584,652...60,671,589
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Ywhah
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
affects binding
ISO
YWHAH protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741
G
Ywhaq
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
affects binding
ISO
YWHAQ protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 6:40,935,714...40,966,240
Ensembl chr 6:40,935,949...40,966,273
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Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
affects binding
ISO
YWHAZ protein binds to phenethyl isothiocyanate
CTD
PMID:21838287
NCBI chr 7:67,941,353...67,963,651
Ensembl chr 7:67,940,017...67,963,668
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Zc3h13
zinc finger CCCH type containing 13
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ZC3H13 mRNA
CTD
PMID:17616710
NCBI chr15:50,607,335...50,671,802
Ensembl chr15:50,607,380...50,671,802
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Zc3h6
zinc finger CCCH type containing 6
increases expression
ISO
phenethyl isothiocyanate results in increased expression of ZC3H6 mRNA
CTD
PMID:26678675
NCBI chr 3:116,203,466...116,254,186
Ensembl chr 3:116,204,197...116,253,282
G
Zfp131
zinc finger protein 131
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ZFP131 mRNA
CTD
PMID:17616710
NCBI chr 2:51,722,774...51,753,662
Ensembl chr 2:51,725,541...51,753,639
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Zfp157
zinc finger protein 157
decreases expression
EXP
phenethyl isothiocyanate results in decreased expression of ZFP157 mRNA
CTD
PMID:17616710
NCBI chr12:16,248,230...16,279,459
Ensembl chr12:16,248,230...16,270,698
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Zfp706
zinc finger protein 706
increases expression
EXP
phenethyl isothiocyanate results in increased expression of ZFP706 mRNA
CTD
PMID:17616710
NCBI chr 7:68,167,496...68,174,121
Ensembl chr 7:68,166,323...68,174,148
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