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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:manganese coordination entity
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Accession:CHEBI:35117 term browser browse the term
Synonyms:related_synonym: manganese coordination compounds;   manganese coordination entities


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mancozeb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase affects activity
multiple interactions		 EXP mancozeb affects the activity of ACHE protein
[carbendazim co-treated with mancozeb] results in increased activity of ACHE protein		 CTD PMID:10641187 PMID:33217513 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Actg1 actin, gamma 1 increases expression ISO mancozeb results in increased expression of ACTG1 protein CTD PMID:21375462 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232 		JBrowse link
G Actmap actin maturation protease decreases expression ISO mancozeb results in decreased expression of ACTMAP mRNA CTD PMID:33396126 NCBI chr 1:82,490,313...82,499,841
Ensembl chr 1:82,490,363...82,499,841 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein CTD PMID:19883720 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin decreases expression ISO mancozeb results in decreased expression of ALB protein CTD PMID:21375462 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity EXP mancozeb results in decreased activity of ALDH2 protein CTD PMID:17010440 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases activity EXP mancozeb results in decreased activity of ALDH5A1 protein CTD PMID:17010440 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Angptl1 angiopoietin-like 1 decreases expression ISO mancozeb results in decreased expression of ANGPTL1 mRNA CTD PMID:33396126 NCBI chr13:68,963,198...68,969,742
Ensembl chr13:68,962,991...68,992,570 		JBrowse link
G Anxa2 annexin A2 decreases expression ISO mancozeb results in decreased expression of ANXA2 protein CTD PMID:21375462 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Apaf1 apoptotic peptidase activating factor 1 increases expression ISO mancozeb results in increased expression of APAF1 protein CTD PMID:22289270 NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540 		JBrowse link
G Ar androgen receptor multiple interactions
decreases expression
decreases activity		 ISO mancozeb inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; mancozeb inhibits the reaction [Metribolone binds to and results in increased activity of AR protein]
mancozeb results in decreased expression of AR mRNA
mancozeb results in decreased activity of AR protein		 CTD PMID:23871939 PMID:33396126 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 decreases expression ISO mancozeb results in decreased expression of ATP1A2 mRNA CTD PMID:33396126 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 ISO mancozeb results in increased expression of BAX mRNA; mancozeb results in increased expression of BAX protein
lupeol inhibits the reaction [mancozeb results in increased expression of BAX mRNA]		 CTD PMID:22289270 PMID:27235710 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions		 ISO
EXP		 mancozeb results in decreased expression of BCL2 mRNA; mancozeb results in decreased expression of BCL2 protein
lupeol inhibits the reaction [mancozeb results in decreased expression of BCL2 mRNA]
alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of BCL2 protein]		 CTD PMID:16005924 PMID:22289270 PMID:27235710 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Car3 carbonic anhydrase 3 increases expression ISO mancozeb results in increased expression of CAR3 protein CTD PMID:21375462 NCBI chr 2:86,770,418...86,780,011
Ensembl chr 2:86,770,420...86,784,280 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions
increases cleavage		 ISO mancozeb results in increased activity of CASP3 protein
Acetylcysteine inhibits the reaction [mancozeb results in increased cleavage of CASP3 protein]
mancozeb results in increased cleavage of and results in increased activity of CASP3 protein		 CTD PMID:22289270 PMID:22824503 PMID:30037311 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases activity ISO mancozeb results in increased activity of CASP7 protein CTD PMID:22824503 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 increases activity ISO mancozeb results in increased activity of CASP8 protein CTD PMID:22289270 PMID:22824503 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions		 ISO mancozeb results in increased activity of CASP9 protein
mancozeb results in increased cleavage of and results in increased activity of CASP9 protein		 CTD PMID:22289270 PMID:22824503 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase multiple interactions
decreases activity		 ISO
EXP		 Acetylcysteine inhibits the reaction [mancozeb results in decreased activity of CAT protein]; lupeol inhibits the reaction [mancozeb results in decreased activity of CAT protein]; Quercetin inhibits the reaction [mancozeb results in decreased activity of CAT protein]
Colforsin inhibits the reaction [mancozeb results in decreased activity of CAT protein]		 CTD PMID:23024109 PMID:27235710 PMID:29283200 PMID:30037311 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccdc106 coiled-coil domain containing 106 decreases expression ISO mancozeb results in decreased expression of CCDC106 mRNA CTD PMID:33396126 NCBI chr 1:68,779,882...68,791,140
Ensembl chr 1:68,779,882...68,786,846 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions
increases expression		 ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein
mancozeb results in increased expression of CCND1 protein		 CTD PMID:19883720 PMID:21375462 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Cdc25c cell division cycle 25C increases phosphorylation ISO mancozeb results in increased phosphorylation of CDC25C protein CTD PMID:21375462 NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression		 ISO lupeol inhibits the reaction [mancozeb results in increased expression of CDKN1A mRNA] CTD PMID:27235710 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cfap126 cilia and flagella associated protein 126 decreases expression ISO mancozeb results in decreased expression of CFAP126 mRNA CTD PMID:33396126 NCBI chr13:83,526,657...83,542,552
Ensembl chr13:83,526,657...83,542,552 		JBrowse link
G Cldn16 claudin 16 decreases expression ISO mancozeb results in decreased expression of CLDN16 mRNA CTD PMID:33396126 NCBI chr11:74,290,298...74,309,588
Ensembl chr11:74,290,298...74,309,588 		JBrowse link
G Ctf1 cardiotrophin 1 decreases expression ISO mancozeb results in decreased expression of CTF1 mRNA CTD PMID:33396126 NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335 		JBrowse link
G Cycs cytochrome c, somatic increases expression ISO mancozeb results in increased expression of CYCS protein CTD PMID:27016407 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
decreases expression		 EXP
ISO		 mancozeb results in decreased activity of CYP1A1 protein
mancozeb results in decreased expression of CYP1A1 protein		 CTD PMID:1946188 PMID:31096615 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 decreases expression ISO mancozeb results in decreased expression of CYP2B6 protein CTD PMID:31096615 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases expression ISO mancozeb results in decreased expression of CYP2E1 mRNA CTD PMID:31096615 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 decreases expression ISO mancozeb results in decreased expression of CYP3A4 mRNA; mancozeb results in decreased expression of CYP3A4 protein CTD PMID:31096615 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression EXP mancozeb results in increased expression of DDIT4 protein CTD PMID:24764117 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Efcab12 EF-hand calcium binding domain 12 decreases expression ISO mancozeb results in decreased expression of EFCAB12 mRNA CTD PMID:33396126 NCBI chr 4:148,869,381...148,892,922
Ensembl chr 4:148,869,387...148,890,560 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation ISO mancozeb results in increased phosphorylation of ELK1 protein CTD PMID:21375462 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO mancozeb results in decreased expression of ESR1 mRNA CTD PMID:33396126 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 decreases expression ISO mancozeb results in decreased expression of ESR2 mRNA; mancozeb results in decreased expression of ESR2 protein CTD PMID:33396126 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G F3 coagulation factor III, tissue factor increases expression ISO mancozeb results in increased expression of F3 protein CTD PMID:25569083 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO mancozeb results in increased expression of FAS protein CTD PMID:22289270 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand increases expression ISO mancozeb results in increased expression of FASLG protein CTD PMID:22289270 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions
increases expression		 ISO lupeol inhibits the reaction [mancozeb results in increased expression of GADD45A mRNA] CTD PMID:27235710 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Glyatl3 glycine-N-acyltransferase-like 3 decreases expression ISO mancozeb results in decreased expression of GLYATL3 mRNA CTD PMID:33396126 NCBI chr 9:19,984,239...19,994,762
Ensembl chr 9:19,977,302...19,995,650 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1 affects activity EXP mancozeb affects the activity of GOT1 protein CTD PMID:10641187 NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633 		JBrowse link
G Gpt glutamic--pyruvic transaminase affects activity EXP mancozeb affects the activity of GPT protein CTD PMID:10641187 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494 		JBrowse link
G Gpx1 glutathione peroxidase 1 decreases expression
multiple interactions		 ISO mancozeb results in decreased expression of GPX1 mRNA
Acetylcysteine inhibits the reaction [mancozeb results in decreased expression of GPX1 mRNA]		 CTD PMID:30037311 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hdac3 histone deacetylase 3 decreases activity ISO mancozeb results in decreased activity of HDAC3 protein CTD PMID:21251949 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac6 histone deacetylase 6 decreases activity ISO mancozeb results in decreased activity of HDAC6 protein CTD PMID:21251949 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Hnrnpm heterogeneous nuclear ribonucleoprotein M increases expression ISO mancozeb results in increased expression of HNRNPM protein CTD PMID:21375462 NCBI chr 7:14,438,703...14,476,781
Ensembl chr 7:14,438,688...14,476,762 		JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 decreases expression ISO mancozeb results in decreased expression of IFITM2 mRNA CTD PMID:33396126 NCBI chr 1:196,051,539...196,052,719
Ensembl chr 1:196,051,537...196,052,741 		JBrowse link
G Ifng interferon gamma multiple interactions ISO mancozeb affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of TNF protein] CTD PMID:15742816 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO mancozeb inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] CTD PMID:16112155 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il2 interleukin 2 affects expression ISO mancozeb affects the expression of IL2 protein CTD PMID:9012323 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Itgb3 integrin subunit beta 3 decreases expression ISO mancozeb results in decreased expression of ITGB3 mRNA; mancozeb results in decreased expression of ITGB3 protein CTD PMID:33396126 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Kcnq2 potassium voltage-gated channel subfamily Q member 2 increases activity EXP mancozeb results in increased activity of KCNQ2 protein CTD PMID:23542819 NCBI chr 3:168,194,776...168,253,831
Ensembl chr 3:168,195,357...168,275,071 		JBrowse link
G Kiss1 KiSS-1 metastasis-suppressor affects expression EXP mancozeb affects the expression of KISS1 mRNA CTD PMID:23660487 NCBI chr13:44,774,823...44,780,707
Ensembl chr13:44,774,823...44,780,612 		JBrowse link
G LOC120094883 small nucleolar RNA SNORD82 increases expression ISO mancozeb results in increased expression of SNORD82 mRNA CTD PMID:33396126 NCBI chr 9:87,004,515...87,004,586
Ensembl chr 9:87,004,515...87,004,586 		JBrowse link
G Ltb4r2 leukotriene B4 receptor 2 increases expression ISO mancozeb results in increased expression of LTB4R2 mRNA CTD PMID:33396126 NCBI chr15:29,258,427...29,260,340
Ensembl chr15:29,259,240...29,260,316 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [mancozeb results in increased activity of MAPK1 protein]; mancozeb results in increased localization of and results in increased activity of MAPK1 protein CTD PMID:21375462 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [mancozeb results in increased activity of MAPK3 protein]; mancozeb results in increased localization of and results in increased activity of MAPK3 protein CTD PMID:21375462 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mdm2 MDM2 proto-oncogene multiple interactions
increases expression		 ISO lupeol inhibits the reaction [mancozeb results in increased expression of MDM2 mRNA] CTD PMID:27235710 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Muc1 mucin 1, cell surface associated decreases expression ISO mancozeb results in decreased expression of MUC1 mRNA; mancozeb results in decreased expression of MUC1 protein CTD PMID:33396126 NCBI chr 2:174,635,559...174,640,738
Ensembl chr 2:174,635,995...174,640,733 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression
decreases expression		 ISO
EXP		 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein
mancozeb results in increased expression of MYC protein
mancozeb results in decreased expression of MYC protein
alpha-Tocopherol inhibits the reaction [mancozeb results in decreased expression of MYC protein]		 CTD PMID:16005924 PMID:19883720 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Nhlrc1 NHL repeat containing E3 ubiquitin protein ligase 1 decreases expression ISO mancozeb results in decreased expression of NHLRC1 mRNA CTD PMID:33396126 NCBI chr17:17,674,375...17,675,565
Ensembl chr17:17,674,319...17,677,148 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions		 ISO mancozeb results in increased expression of NOS2 mRNA
Acetylcysteine inhibits the reaction [mancozeb results in increased expression of NOS2 mRNA]		 CTD PMID:30037311 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
increases expression		 ISO Acetylcysteine inhibits the reaction [mancozeb results in increased expression of NOX4 mRNA] CTD PMID:30037311 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Odc1 ornithine decarboxylase 1 increases activity ISO mancozeb results in increased activity of ODC1 protein CTD PMID:1733566 NCBI chr 6:40,329,831...40,336,444
Ensembl chr 6:40,329,964...40,336,440 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase multiple interactions
decreases expression		 ISO lupeol inhibits the reaction [mancozeb results in decreased expression of OGG1 mRNA] CTD PMID:27235710 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Or1s2 olfactory receptor family 1 subfamily S member 2 increases expression ISO mancozeb results in increased expression of OR1S1 mRNA CTD PMID:33396126 NCBI chr 1:210,913,992...210,914,939
Ensembl chr 1:210,911,289...210,915,657 		JBrowse link
G Pcdhb20 protocadherin beta 20 decreases expression ISO mancozeb results in decreased expression of PCDHB14 mRNA CTD PMID:33396126 NCBI chr18:29,211,883...29,215,258
Ensembl chr18:29,211,883...29,215,258 		JBrowse link
G Prdx2 peroxiredoxin 2 increases expression ISO mancozeb results in increased expression of PRDX2 protein CTD PMID:21375462 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prl prolactin multiple interactions
increases expression		 ISO [mancozeb co-treated with imidacloprid] results in increased expression of PRL protein
mancozeb results in increased expression of PRL mRNA		 CTD PMID:24530807 PMID:33396126 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Ptges prostaglandin E synthase increases expression
decreases expression
multiple interactions		 ISO mancozeb results in increased expression of PTGES mRNA
mancozeb results in decreased expression of PTGES protein
lupeol inhibits the reaction [mancozeb results in increased expression of PTGES mRNA]		 CTD PMID:27235710 PMID:32446389 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptges3 prostaglandin E synthase 3 decreases expression ISO mancozeb results in decreased expression of PTGES3 mRNA CTD PMID:32446389 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO mancozeb results in increased expression of PTGS2 protein CTD PMID:21375462 PMID:32446389 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form CTD PMID:19883720 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Pvalb parvalbumin increases expression ISO mancozeb results in increased expression of PVALB protein CTD PMID:21375462 NCBI chr 7:109,772,939...109,787,954
Ensembl chr 7:109,772,593...109,784,561 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit increases phosphorylation
affects localization
multiple interactions
increases localization		 ISO mancozeb results in increased phosphorylation of RELA protein
mancozeb affects the localization of RELA protein
Acetylcysteine inhibits the reaction [mancozeb affects the localization of RELA protein]; lupeol inhibits the reaction [mancozeb affects the localization of RELA protein]; mancozeb inhibits the reaction [Lipopolysaccharides affects the localization of and results in increased activity of RELA protein]
mancozeb results in increased localization of RELA protein		 CTD PMID:16112155 PMID:21375462 PMID:22289270 PMID:27235710 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression ISO mancozeb results in increased expression of S100A6 protein CTD PMID:21375462 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180 		JBrowse link
G S100a9 S100 calcium binding protein A9 increases expression ISO mancozeb results in increased expression of S100A9 protein CTD PMID:21375462 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Scx scleraxis bHLH transcription factor decreases expression ISO mancozeb results in decreased expression of SCX mRNA CTD PMID:33396126 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626 		JBrowse link
G Septin11 septin 11 increases expression ISO mancozeb results in increased expression of SEPTIN11 mRNA CTD PMID:33396126 NCBI chr14:14,844,759...14,990,856
Ensembl chr14:14,844,580...14,990,853 		JBrowse link
G Serpinf1 serpin family F member 1 decreases expression ISO mancozeb results in decreased expression of SERPINF1 mRNA CTD PMID:33396126 NCBI chr10:60,250,198...60,262,593
Ensembl chr10:60,249,708...60,262,646 		JBrowse link
G Sirt1 sirtuin 1 decreases activity ISO mancozeb results in decreased activity of SIRT1 protein CTD PMID:21251949 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 decreases activity ISO mancozeb results in decreased activity of SIRT2 protein CTD PMID:21251949 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt3 sirtuin 3 decreases activity ISO mancozeb results in decreased activity of SIRT3 protein CTD PMID:21251949 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slc14a1 solute carrier family 14 member 1 (Kidd blood group) decreases expression ISO mancozeb results in decreased expression of SLC14A1 mRNA CTD PMID:33396126 NCBI chr18:71,565,453...71,608,807
Ensembl chr18:71,565,454...71,595,146 		JBrowse link
G Slc5a5 solute carrier family 5 member 5 multiple interactions ISO mancozeb inhibits the reaction [SLC5A5 protein results in increased uptake of Iodine] CTD PMID:27979590 NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697 		JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO mancozeb results in decreased expression of SOD1 protein CTD PMID:21375462 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sult2b1 sulfotransferase family 2B member 1 decreases expression ISO mancozeb results in decreased expression of SULT2B1 mRNA CTD PMID:33396126 NCBI chr 1:96,200,155...96,261,295
Ensembl chr 1:96,200,156...96,261,295 		JBrowse link
G Tek TEK receptor tyrosine kinase increases activity ISO mancozeb results in increased activity of TEK protein CTD PMID:21251949 NCBI chr 5:109,607,077...109,733,805
Ensembl chr 5:109,607,077...109,733,804 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 decreases expression ISO mancozeb results in decreased expression of TGFB1I1 mRNA CTD PMID:33396126 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO mancozeb affects the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased secretion of TNF protein]
mancozeb inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; mancozeb inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; mancozeb inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]		 CTD PMID:15742816 PMID:15893782 PMID:16112155 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tp53 tumor protein p53 decreases expression
increases expression
multiple interactions		 ISO mancozeb results in decreased expression of TRP53 mRNA; mancozeb results in decreased expression of TRP53 protein
mancozeb results in increased expression of TP53 mRNA
lupeol inhibits the reaction [mancozeb results in increased expression of TP53 mRNA]		 CTD PMID:22369882 PMID:27235710 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpi1 triosephosphate isomerase 1 increases expression ISO mancozeb results in increased expression of TPI1 protein CTD PMID:21375462 NCBI chr 4:157,615,283...157,618,813
Ensembl chr 4:157,615,386...157,619,541 		JBrowse link
G Tpo thyroid peroxidase decreases activity EXP mancozeb results in decreased activity of TPO protein CTD PMID:9418944 NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199 		JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions ISO [mancozeb co-treated with imidacloprid] results in increased expression of TSHB protein CTD PMID:24530807 NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 decreases expression
multiple interactions		 ISO mancozeb results in decreased expression of XRCC1 mRNA
lupeol inhibits the reaction [mancozeb results in decreased expression of XRCC1 mRNA]		 CTD PMID:27235710 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Zfp358 zinc finger protein 358 decreases expression ISO mancozeb results in decreased expression of ZNF358 mRNA CTD PMID:33396126 NCBI chr12:1,552,367...1,556,460
Ensembl chr12:1,552,366...1,556,460 		JBrowse link
maneb term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acads acyl-CoA dehydrogenase short chain multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ACADS mRNA] CTD PMID:23963992 NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898 		JBrowse link
G Ache acetylcholinesterase decreases expression
multiple interactions		 EXP
ISO		 Maneb results in decreased expression of ACHE protein
[LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of ACHE mRNA		 CTD PMID:3868355 PMID:23017109 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Aco2 aconitase 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ACO2 mRNA CTD PMID:18386188 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Adam22 ADAM metallopeptidase domain 22 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ADAM22 mRNA CTD PMID:22563483 NCBI chr 4:25,716,055...25,970,932
Ensembl chr 4:25,715,990...25,964,962 		JBrowse link
G Adgrb1 adhesion G protein-coupled receptor B1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ADGRB1 mRNA CTD PMID:23017109 NCBI chr 7:106,404,844...106,476,902
Ensembl chr 7:106,404,958...106,476,902 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ADGRG1 mRNA CTD PMID:18386188 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108 		JBrowse link
G Adora1 adenosine A1 receptor multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ADORA1 mRNA CTD PMID:23017109 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ago3 argonaute RISC catalytic component 3 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of AGO3 mRNA CTD PMID:22563483 NCBI chr 5:138,632,367...138,714,230
Ensembl chr 5:138,639,569...138,714,230 		JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of AIF1 protein; [Paraquat co-treated with Maneb] results in increased expression of AIF1 protein; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of AIF1 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of AIF1 protein] CTD PMID:28202386 PMID:32375810 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AKR1B3 mRNA CTD PMID:18386188 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of AKT1 protein; [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of AKT1 protein; [Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of AKT1 mRNA] CTD PMID:19883720 PMID:23963992 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alas2 5'-aminolevulinate synthase 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ALAS2 mRNA CTD PMID:22563483 NCBI chr  X:19,463,146...19,486,526
Ensembl chr  X:19,463,171...19,486,519 		JBrowse link
G Aldh2 aldehyde dehydrogenase 2 family member decreases activity EXP Maneb results in decreased activity of ALDH2 protein CTD PMID:17010440 NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521 		JBrowse link
G Aldh5a1 aldehyde dehydrogenase 5 family, member A1 decreases activity
multiple interactions		 EXP
ISO		 Maneb results in decreased activity of ALDH5A1 protein
[Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ALDH5A1 mRNA]		 CTD PMID:17010440 PMID:23963992 NCBI chr17:40,132,339...40,158,677
Ensembl chr17:40,130,883...40,158,677 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ALDOC mRNA CTD PMID:18386188 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Amn amnion associated transmembrane protein multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of AMN mRNA CTD PMID:22563483 NCBI chr 6:130,311,372...130,318,815
Ensembl chr 6:130,311,372...130,318,815 		JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AP3B2 mRNA CTD PMID:18386188 NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191 		JBrowse link
G Ap3d1 adaptor related protein complex 3 subunit delta 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of AP3D1 mRNA CTD PMID:18386188 NCBI chr 7:8,970,249...9,005,651
Ensembl chr 7:8,970,291...9,005,643 		JBrowse link
G Apbb1 amyloid beta precursor protein binding family B member 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of APBB1 mRNA CTD PMID:23017109 NCBI chr 1:159,896,889...159,920,505
Ensembl chr 1:159,896,880...159,920,627 		JBrowse link
G Arf3 ADP-ribosylation factor 3 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ARF3 mRNA CTD PMID:18386188 NCBI chr 7:129,886,082...129,912,022
Ensembl chr 7:129,886,082...129,912,002 		JBrowse link
G Arg1 arginase 1 decreases expression
multiple interactions		 ISO Maneb results in decreased expression of ARG1 mRNA
[Maneb co-treated with Paraquat] results in increased expression of ARG1 mRNA; [Paraquat co-treated with Maneb] results in increased expression of ARG1 mRNA; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ARG1 mRNA]		 CTD PMID:29568078 PMID:32194361 PMID:32375810 PMID:34052309 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arnt2 aryl hydrocarbon receptor nuclear translocator 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of ARNT2 mRNA CTD PMID:23017109 NCBI chr 1:138,236,235...138,392,868
Ensembl chr 1:138,189,940...138,393,153 		JBrowse link
G Ascl1 achaete-scute family bHLH transcription factor 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ASCL1 mRNA CTD PMID:23017109 NCBI chr 7:21,904,153...21,906,003
Ensembl chr 7:21,903,126...21,905,993 		JBrowse link
G Atg12 autophagy related 12 multiple interactions ISO Maneb promotes the reaction [Paraquat results in increased expression of ATG12 protein] CTD PMID:22292029 NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418 		JBrowse link
G Atp5f1a ATP synthase F1 subunit alpha multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP5A1 protein] CTD PMID:23562983 NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794 		JBrowse link
G Atp5mc1 ATP synthase membrane subunit c locus 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP5G1 mRNA CTD PMID:18386188 NCBI chr10:81,024,056...81,026,780
Ensembl chr10:81,023,925...81,027,124
Ensembl chr10:81,023,925...81,027,124 		JBrowse link
G Atp6v0b ATPase H+ transporting V0 subunit B multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP6V0B mRNA CTD PMID:18386188 NCBI chr 5:131,423,384...131,424,900
Ensembl chr 5:131,423,387...131,426,401 		JBrowse link
G Atp6v0c ATPase H+ transporting V0 subunit C multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of ATP6V0C mRNA CTD PMID:18386188 NCBI chr10:13,196,204...13,202,580
Ensembl chr10:13,196,204...13,201,500 		JBrowse link
G Atp6v1c1 ATPase H+ transporting V1 subunit C1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ATP6V1C1 mRNA] CTD PMID:23963992 NCBI chr 7:69,834,464...69,872,278
Ensembl chr 7:69,834,463...69,872,278 		JBrowse link
G Atp8a2 ATPase phospholipid transporting 8A2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ATP8A2 mRNA CTD PMID:22563483 NCBI chr15:33,817,309...34,350,193
Ensembl chr15:33,819,755...34,350,223 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions ISO [Paraquat co-treated with Maneb] results in increased phosphorylation of BAD protein CTD PMID:15824117 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions
increases expression
affects response to substance		 ISO [Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAK1 mRNA]
[Paraquat co-treated with Maneb] results in increased expression of BAK1 protein; Maneb inhibits the reaction [BAK1 protein affects the susceptibility to Paraquat]; Paraquat inhibits the reaction [BAK1 protein affects the susceptibility to Maneb]
Maneb results in increased expression of BAK1 mRNA; Maneb results in increased expression of BAK1 protein		 CTD PMID:18266926 PMID:23963992 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] results in increased expression of BAX protein; BAX protein affects the susceptibility to [Paraquat co-treated with Maneb]
Maneb results in increased expression of BAX protein
[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA; [Paraquat co-treated with Maneb] results in increased expression of BAX protein; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BAX protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of BAX mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BAX protein]		 CTD PMID:15824117 PMID:18266926 PMID:20964710 PMID:23963992 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression
multiple interactions		 ISO Maneb results in increased expression of BBC3 protein
3-(4-(morpholin-4-yl)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)benzonitrile inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BBC3 protein]; [Paraquat co-treated with Maneb] results in increased expression of BBC3 protein; Plant Extracts inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of BBC3 protein]		 CTD PMID:18266926 PMID:34897981 NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression		 ISO [Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of BCL2 mRNA]
Maneb results in increased expression of BCL2 mRNA; Maneb results in increased expression of BCL2 protein		 CTD PMID:18266926 PMID:23963992 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression
multiple interactions		 ISO Maneb results in increased expression of BCL2A1 mRNA
[Paraquat co-treated with Maneb] results in increased expression of BCL2A1 protein		 CTD PMID:18266926 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] results in decreased expression of BCL2L1 protein
Maneb results in increased expression of BCL2L1 mRNA		 CTD PMID:15824117 PMID:18266926 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression
multiple interactions		 ISO Maneb results in increased expression of BCL2L11 protein
[Paraquat co-treated with Maneb] results in increased expression of BCL2L11 protein		 CTD PMID:18266926 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO
EXP		 [Maneb co-treated with Paraquat] results in decreased expression of BDNF mRNA
[Paraquat co-treated with Maneb] results in decreased expression of BDNF mRNA; [Paraquat co-treated with Maneb] results in decreased expression of BDNF protein; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of BDNF mRNA]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of BDNF protein]		 CTD PMID:23017109 PMID:27460631 PMID:33368748 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions		 ISO Maneb results in increased expression of BECN1 protein
[Paraquat co-treated with Maneb] results in increased expression of BECN1 protein		 CTD PMID:22292029 PMID:26884967 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bicd1 BICD cargo adaptor 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of BICD1 mRNA CTD PMID:22563483 NCBI chr 4:182,479,071...182,631,504
Ensembl chr 4:182,479,071...182,627,434 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression
multiple interactions		 ISO Maneb results in increased expression of BID protein
[Maneb co-treated with Paraquat] results in increased expression of BID protein		 CTD PMID:18266926 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Bik BCL2-interacting killer increases expression
multiple interactions		 ISO Maneb results in increased expression of BIK mRNA; Maneb results in increased expression of BIK protein
[Paraquat co-treated with Maneb] results in increased expression of BIK protein		 CTD PMID:18266926 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Bmp2 bone morphogenetic protein 2 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP2 mRNA CTD PMID:23017109 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA CTD PMID:23017109 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bnip3 BCL2 interacting protein 3 increases expression ISO Maneb results in increased expression of BNIP3 mRNA; Maneb results in increased expression of BNIP3 protein CTD PMID:18266926 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like increases expression ISO Maneb results in increased expression of BNIP3L mRNA CTD PMID:18266926 NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G Brf1 BRF1, RNA polymerase III transcription initiation factor subunit multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of BRF1 mRNA CTD PMID:18386188 NCBI chr 6:132,034,380...132,081,296
Ensembl chr 6:132,037,272...132,081,278 		JBrowse link
G Cacna1e calcium voltage-gated channel subunit alpha1 E multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CACNA1E mRNA CTD PMID:22563483 NCBI chr13:66,574,659...67,063,443
Ensembl chr13:66,581,920...66,894,450 		JBrowse link
G Cacybp calcyclin binding protein multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CACYBP mRNA CTD PMID:18386188 NCBI chr13:72,437,485...72,447,810
Ensembl chr13:72,437,490...72,450,177 		JBrowse link
G Calm1 calmodulin 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CALM1 mRNA] CTD PMID:23963992 NCBI chr 6:119,487,691...119,495,759
Ensembl chr 6:119,487,621...119,498,227 		JBrowse link
G Calm2 calmodulin 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CALM2 mRNA CTD PMID:18386188 NCBI chr 6:7,091,624...7,104,284
Ensembl chr 6:7,091,567...7,104,287 		JBrowse link
G Camp cathelicidin antimicrobial peptide multiple interactions ISO
EXP		 [Paraquat co-treated with Maneb] affects the expression of CAMP mRNA
[Paraquat co-treated with Maneb] results in decreased expression of CAMP mRNA		 CTD PMID:22563483 PMID:27460631 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543 		JBrowse link
G Capn11 calpain 11 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CAPN11 mRNA CTD PMID:22563483 NCBI chr 9:15,344,059...15,365,604
Ensembl chr 9:15,344,089...15,365,601 		JBrowse link
G Casp1 caspase 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased cleavage of CASP1 protein; [Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA; [Paraquat co-treated with Maneb] results in increased cleavage of CASP1 protein; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased cleavage of CASP1 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased cleavage of CASP1 protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased cleavage of CASP1 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP1 mRNA] CTD PMID:23963992 PMID:32375810 PMID:34052309 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 ISO Maneb results in increased activity of CASP3 protein
3-(4-(morpholin-4-yl)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)benzonitrile inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP3 protein modified form]; [Paraquat co-treated with Maneb] results in increased expression of CASP3 protein modified form; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP3 protein modified form]; Plant Extracts inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP3 protein modified form]		 CTD PMID:22824503 PMID:34897981 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp7 caspase 7 increases activity ISO Maneb results in increased activity of CASP7 protein CTD PMID:22824503 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729 		JBrowse link
G Casp8 caspase 8 increases activity ISO Maneb results in increased activity of CASP8 protein CTD PMID:22824503 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity		 ISO [Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA; [Paraquat co-treated with Maneb] results in increased expression of CASP9 protein; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP9 protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CASP9 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP9 protein]
Maneb results in increased activity of CASP9 protein		 CTD PMID:20964710 PMID:22824503 PMID:23963992 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases activity
multiple interactions		 ISO
EXP		 Maneb results in decreased activity of CAT protein
[Maneb co-treated with Paraquat] results in increased expression of CAT mRNA		 CTD PMID:26210702 PMID:29859004 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Ccdc88a coiled coil domain containing 88A multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CCDC88A mRNA CTD PMID:22563483 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CCL19 mRNA CTD PMID:22563483 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl21 C-C motif chemokine ligand 21 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CCL21 mRNA; [Paraquat co-treated with Maneb] affects the expression of CCL21A mRNA CTD PMID:22563483 NCBI chr 5:56,980,557...56,981,661
Ensembl chr 5:56,980,558...56,981,686 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO
EXP		 [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of CCND1 protein
[Maneb co-treated with Paraquat] results in decreased expression of CCND1 mRNA		 CTD PMID:19883720 PMID:29859004 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccnd2 cyclin D2 multiple interactions EXP [Maneb co-treated with Paraquat] results in decreased expression of CCND2 mRNA CTD PMID:29859004 NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495 		JBrowse link
G Cd34 CD34 molecule increases expression EXP Maneb results in increased expression of CD34 CTD PMID:25803990 NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cd68 Cd68 molecule multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CD68 mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CD68 mRNA] CTD PMID:32169474 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cdhr4 cadherin-related family member 4 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CDHR4 mRNA CTD PMID:22563483 NCBI chr 8:108,682,594...108,690,358
Ensembl chr 8:108,682,613...108,690,367 		JBrowse link
G Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CDIPT mRNA CTD PMID:18386188 NCBI chr 1:181,583,098...181,587,409
Ensembl chr 1:181,583,141...181,587,408 		JBrowse link
G Cdk2 cyclin dependent kinase 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CDK2 mRNA] CTD PMID:23963992 NCBI chr 7:1,129,878...1,137,431
Ensembl chr 7:1,129,811...1,137,403 		JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CDK5R1 mRNA CTD PMID:23017109 NCBI chr10:65,484,266...65,485,467
Ensembl chr10:65,483,941...65,488,456 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CDK5RAP1 mRNA CTD PMID:23017109 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Cdk5rap2 CDK5 regulatory subunit associated protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA; LRRK2 protein mutant form inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA]; SNCA protein inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA] CTD PMID:23017109 NCBI chr 5:83,792,282...83,961,129
Ensembl chr 5:83,792,284...83,960,782 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of CDKN1A mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDKN1A mRNA] CTD PMID:23963992 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A multiple interactions
increases expression		 EXP [Maneb co-treated with Paraquat] results in increased expression of CDKN2A mRNA
Maneb results in increased expression of CDKN2A mRNA		 CTD PMID:29859004 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CEBPD mRNA CTD PMID:22563483 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Cep290 centrosomal protein 290 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CEP290 mRNA CTD PMID:22563483 NCBI chr 7:35,310,071...35,399,392
Ensembl chr 7:35,310,199...35,399,392 		JBrowse link
G Chrm2 cholinergic receptor, muscarinic 2 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CHRM2 mRNA CTD PMID:23017109 NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103 		JBrowse link
G Chuk component of inhibitor of nuclear factor kappa B kinase complex multiple interactions ISO [Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of CHUK protein] CTD PMID:29568078 NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065 		JBrowse link
G Cirbp cold inducible RNA binding protein multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CIRBP mRNA CTD PMID:18386188 NCBI chr 7:9,533,857...9,538,899
Ensembl chr 7:9,424,178...9,538,818 		JBrowse link
G Clca1 chloride channel accessory 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of CLCA1 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CLCA1 mRNA] CTD PMID:23963992 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369 		JBrowse link
G Clu clusterin multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CLU mRNA CTD PMID:18386188 NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315 		JBrowse link
G Cope COPI coat complex subunit epsilon multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COPE mRNA CTD PMID:18386188 NCBI chr16:19,114,871...19,125,527
Ensembl chr16:19,114,871...19,128,907 		JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of COX5A protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein]; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX5A protein] CTD PMID:23562983 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781 		JBrowse link
G Cox6a1 cytochrome c oxidase subunit 6A1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COX6A1 mRNA CTD PMID:18386188 NCBI chr12:41,261,983...41,265,037
Ensembl chr12:41,261,967...41,265,041 		JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of COX6B1 mRNA] CTD PMID:23963992 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001 		JBrowse link
G Cox7a2 cytochrome c oxidase subunit 7A2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COX7A2 mRNA CTD PMID:18386188 NCBI chr 8:80,716,824...80,720,922
Ensembl chr14:51,301,168...51,301,633 		JBrowse link
G Cox7a2l cytochrome c oxidase subunit 7A2 like multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of COX7A2L mRNA CTD PMID:18386188 NCBI chr 6:11,184,284...11,198,287
Ensembl chr 6:11,184,285...11,198,273 		JBrowse link
G Cplx1 complexin 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CPLX1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of CPLX1 protein CTD PMID:17532186 NCBI chr14:1,184,638...1,216,392 JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO
EXP		 [Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of CREB1 mRNA]
[Paraquat co-treated with Maneb] results in decreased expression of and results in decreased phosphorylation of CREB1 protein; [Paraquat co-treated with Maneb] results in decreased expression of CREB1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of CREB1 protein; [Paraquat co-treated with Maneb] results in decreased expression of CREB1 protein modified form; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of and results in decreased phosphorylation of CREB1 protein]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of CREB1 mRNA]		 CTD PMID:23963992 PMID:27460631 PMID:33368748 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816 		JBrowse link
G Crip2 cysteine-rich protein 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CRIP2 mRNA CTD PMID:18386188 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065 		JBrowse link
G Crlf2 cytokine receptor-like factor 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of CRLF2 mRNA CTD PMID:22563483 NCBI chr14:103,943...108,643
Ensembl chr14:103,939...108,642 		JBrowse link
G Crot carnitine O-octanoyltransferase multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CROT mRNA CTD PMID:18386188 NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109 		JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CSF1R mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CSF1R mRNA] CTD PMID:32169474 NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415 		JBrowse link
G Csf2ra colony stimulating factor 2 receptor subunit alpha multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CSF2RA mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CSF2RA mRNA] CTD PMID:32169474 NCBI chr14:98,089...103,261
Ensembl chr14:89,172...103,128 		JBrowse link
G Ctsl cathepsin L multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of CTSL mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CTSL mRNA] CTD PMID:23963992 NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548 		JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of CYBB mRNA; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYBB mRNA]; diphenyleneiodonium inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYBB mRNA]
[Maneb co-treated with Paraquat] results in increased expression of CYBB protein; [Paraquat co-treated with Maneb] results in increased expression of CYBB protein; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CYBB protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYBB protein]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYBB protein]		 CTD PMID:29568078 PMID:30797899 PMID:32375810 PMID:34052309 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyc1 cytochrome c-1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of CYC1 mRNA CTD PMID:18386188 NCBI chr 7:108,067,106...108,069,483
Ensembl chr 7:108,067,115...108,069,479 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases activity
decreases expression
increases expression		 EXP
ISO		 Maneb results in increased activity of CYP1A1 protein
Maneb results in decreased expression of CYP1A1 mRNA
Maneb results in increased expression of CYP1A1 mRNA; Maneb results in increased expression of CYP1A1 protein		 CTD PMID:20888808 PMID:32194361 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions EXP [Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein; [Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA] CTD PMID:23159886 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 decreases expression ISO Maneb results in decreased expression of CYP2C19 protein CTD PMID:32194361 NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596 		JBrowse link
G Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 multiple interactions
decreases expression		 ISO Ketoconazole inhibits the reaction [Maneb results in decreased expression of CYP2D22 protein] CTD PMID:22334051 NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 decreases activity
increases expression
multiple interactions
increases activity		 EXP
ISO		 Maneb results in decreased activity of CYP2E1 protein
Maneb results in increased expression of CYP2E1 mRNA; Maneb results in increased expression of CYP2E1 protein
[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein; [Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA; Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]; Maneb results in increased expression of and results in increased activity of CYP2E1 protein; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Silymarin inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]
Maneb results in increased activity of CYP2E1 protein
[Maneb co-treated with Paraquat] results in increased expression of CYP2E1 mRNA; [Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein; [Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of CYP2E1 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]		 CTD PMID:11043497 PMID:16510128 PMID:20888808 PMID:20964710 PMID:23159886 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023 		JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 decreases expression ISO Maneb results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688 		JBrowse link
G Dap3 death associated protein 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of DAP3 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DAP3 mRNA] CTD PMID:23963992 NCBI chr 2:174,319,341...174,347,489
Ensembl chr 2:174,318,983...174,346,461 		JBrowse link
G Dbi diazepam binding inhibitor multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of DBI mRNA CTD PMID:18386188 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression EXP Maneb results in increased expression of DDIT4 protein CTD PMID:24764117 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105 		JBrowse link
G Ddx5 DEAD-box helicase 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of DDX5 mRNA CTD PMID:18386188 NCBI chr10:91,723,508...91,732,210
Ensembl chr10:91,723,508...91,732,283 		JBrowse link
G Dgki diacylglycerol kinase, iota multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of DGKI mRNA CTD PMID:22563483 NCBI chr 4:65,410,878...65,872,733
Ensembl chr 4:65,420,108...65,872,733 		JBrowse link
G Dio1 iodothyronine deiodinase 1 decreases activity ISO Maneb results in decreased activity of DIO1 protein CTD PMID:29228274 NCBI chr 5:122,074,285...122,090,983
Ensembl chr 5:122,074,279...122,090,970 		JBrowse link
G Dip2b disco-interacting protein 2 homolog B multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of DIP2B mRNA CTD PMID:22563483 NCBI chr 7:131,174,575...131,350,417
Ensembl chr 7:131,174,567...131,349,092 		JBrowse link
G Dll1 delta like canonical Notch ligand 1 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DLL1 mRNA CTD PMID:23017109 NCBI chr 1:56,312,062...56,320,177
Ensembl chr 1:56,312,066...56,320,179 		JBrowse link
G Dlst dihydrolipoamide S-succinyltransferase multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of DLST protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DLST protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of DLST protein] CTD PMID:23562983 NCBI chr 6:104,758,511...104,783,296
Ensembl chr 6:104,758,631...104,783,296 		JBrowse link
G Dmrta2 DMRT-like family A2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of DMRTA2 mRNA CTD PMID:22563483 NCBI chr 5:124,805,883...124,811,694
Ensembl chr 5:124,805,883...124,811,630 		JBrowse link
G Dnajb6 DnaJ heat shock protein family (Hsp40) member B6 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of DNAJB6 mRNA CTD PMID:18386188 NCBI chr 4:5,452,683...5,556,679
Ensembl chr 4:5,452,683...5,556,659 		JBrowse link
G Dnm2 dynamin 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of DNM2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of DNM2 mRNA] CTD PMID:23963992 NCBI chr 8:19,978,313...20,060,162
Ensembl chr 8:19,978,400...20,060,157 		JBrowse link
G Drd2 dopamine receptor D2 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DRD2 mRNA CTD PMID:23017109 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd4 dopamine receptor D4 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of DRD4 protein CTD PMID:22563483 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553 		JBrowse link
G Drd5 dopamine receptor D5 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DRD5 mRNA CTD PMID:23017109 NCBI chr14:72,489,347...72,490,774
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G E2f1 E2F transcription factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of E2F1 mRNA] CTD PMID:23963992 NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of EEF1A1 mRNA CTD PMID:18386188 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Eef1g eukaryotic translation elongation factor 1 gamma multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EEF1G mRNA] CTD PMID:23963992 NCBI chr 1:205,860,713...205,871,319
Ensembl chr 1:205,860,698...205,872,382 		JBrowse link
G Efnb1 ephrin B1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of EFNB1 mRNA CTD PMID:23017109 NCBI chr  X:64,257,351...64,270,158
Ensembl chr  X:64,257,351...64,270,157 		JBrowse link
G Egr4 early growth response 4 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of EGR4 mRNA CTD PMID:22563483 NCBI chr 4:118,047,869...118,050,328
Ensembl chr 4:118,047,869...118,050,328 		JBrowse link
G Eif4g2 eukaryotic translation initiation factor 4, gamma 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of EIF4G2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of EIF4G2 mRNA] CTD PMID:23963992 NCBI chr 1:165,181,433...165,193,583
Ensembl chr 1:165,181,434...165,193,588 		JBrowse link
G Elk1 ETS transcription factor ELK1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ELK1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ELK1 mRNA] CTD PMID:23963992 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Eno1 enolase 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of ENO1 protein; [Paraquat co-treated with Maneb] results in decreased expression of ENO1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of ENO1 protein; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ENO1 protein] CTD PMID:17532186 PMID:18386188 PMID:23562983 NCBI chr 5:160,719,951...160,731,337
Ensembl chr 5:160,719,951...160,731,336 		JBrowse link
G Eno2 enolase 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of ENO2 protein CTD PMID:23562983 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980 		JBrowse link
G Etl4 enhancer trap locus 4 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ETL4 mRNA CTD PMID:22563483 NCBI chr17:82,841,075...83,304,868
Ensembl chr17:82,495,041...83,304,715 		JBrowse link
G Fas Fas cell surface death receptor multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of FAS mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FAS mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FAS mRNA] CTD PMID:23963992 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Fez1 fasciculation and elongation protein zeta 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of FEZ1 mRNA CTD PMID:23017109 NCBI chr 8:36,544,462...36,589,684
Ensembl chr 8:36,544,535...36,589,683 		JBrowse link
G Fgfr3 fibroblast growth factor receptor 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of FGFR3 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FGFR3 mRNA] CTD PMID:23963992 NCBI chr14:76,987,242...77,002,671
Ensembl chr14:76,987,993...77,003,341 		JBrowse link
G Fkbp4 FKBP prolyl isomerase 4 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of FKBP4 mRNA CTD PMID:18386188 NCBI chr 4:161,703,379...161,711,833
Ensembl chr 4:161,703,379...161,711,833 		JBrowse link
G Fkbp5 FKBP prolyl isomerase 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of FKBP5 mRNA CTD PMID:18386188 NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions ISO
EXP		 [Maneb co-treated with Paraquat] results in increased expression of FOS mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of FOS mRNA]
[Paraquat co-treated with Maneb] results in decreased expression of FOS mRNA; [Paraquat co-treated with Maneb] results in decreased expression of FOS protein; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of FOS mRNA]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of FOS protein]		 CTD PMID:23963992 PMID:27460631 PMID:33368748 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fxyd6 FXYD domain-containing ion transport regulator 6 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of FXYD6 mRNA CTD PMID:18386188 NCBI chr 8:45,679,054...45,705,958
Ensembl chr 8:45,678,885...45,705,958 		JBrowse link
G G6pc1 glucose-6-phosphatase catalytic subunit 1 decreases expression ISO Maneb results in decreased expression of G6PC1 mRNA CTD PMID:32194361 NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804 		JBrowse link
G Gabra6 gamma-aminobutyric acid type A receptor subunit alpha6 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GABRA6 mRNA CTD PMID:22563483 NCBI chr10:26,810,411...26,825,768
Ensembl chr10:26,810,423...26,825,769 		JBrowse link
G Gas5 growth arrest specific 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GAS5 mRNA CTD PMID:18386188 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
increases activity		 ISO
EXP		 [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of GCLC mRNA
Maneb results in increased activity of GCLC protein		 CTD PMID:15527874 PMID:21402726 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gfap glial fibrillary acidic protein multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of GFAP protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of GFAP protein] CTD PMID:30797899 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589 		JBrowse link
G Gh1 growth hormone 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GH mRNA CTD PMID:22563483 NCBI chr10:91,228,102...91,230,079
Ensembl chr10:91,228,103...91,230,078 		JBrowse link
G Gm2a ganglioside GM2 activator multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GM2A mRNA CTD PMID:18386188 NCBI chr10:39,219,221...39,231,756
Ensembl chr10:39,219,243...39,231,757 		JBrowse link
G Gmfb glia maturation factor, beta multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GMFB mRNA; [Paraquat co-treated with Maneb] results in decreased expression of GMFB protein CTD PMID:17532186 NCBI chr15:20,069,923...20,081,005
Ensembl chr15:20,067,263...20,080,331 		JBrowse link
G Gng5 G protein subunit gamma 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GNG5 mRNA CTD PMID:18386188 NCBI chr 2:235,394,680...235,403,177
Ensembl chr 1:77,292,043...77,292,513 		JBrowse link
G Gngt2 G protein subunit gamma transducin 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GNGT2 mRNA CTD PMID:22563483 NCBI chr10:80,776,003...80,784,235 JBrowse link
G Gpr27 G protein-coupled receptor 27 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of GPR27 mRNA CTD PMID:22563483 NCBI chr 4:132,328,364...132,329,497
Ensembl chr 4:132,328,364...132,329,497 		JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
decreases expression		 ISO
EXP		 GPX1 protein results in decreased susceptibility to [Paraquat co-treated with Maneb]
[Maneb co-treated with Paraquat] results in increased expression of GPX1 mRNA
Maneb results in decreased expression of GPX1 mRNA		 CTD PMID:15824117 PMID:26210702 PMID:29859004 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gpx4 glutathione peroxidase 4 increases expression
multiple interactions		 ISO Maneb results in increased expression of GPX4 mRNA
[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein
[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of GPX4 protein]; NFE2L2 gene mutant form inhibits the reaction [Maneb results in increased expression of GPX4 mRNA]		 CTD PMID:23764462 PMID:30797899 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982 		JBrowse link
G Grb2 growth factor receptor bound protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GRB2 mRNA] CTD PMID:23963992 NCBI chr10:100,881,404...100,949,193
Ensembl chr10:100,869,718...100,949,309 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] affects the phosphorylation of GSK3B protein CTD PMID:19883720 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP
ISO		 [Acetylcysteine co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein; [Silymarin co-treated with Maneb] results in increased activity of GSR protein; [Silymarin co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein
[NFE2L2 gene mutant form results in increased susceptibility to Maneb] which results in decreased expression of GSR protein		 CTD PMID:23159886 PMID:23764462 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gsta3 glutathione S-transferase alpha 3 increases expression EXP Maneb results in increased expression of GSTA3 mRNA CTD PMID:20888808 NCBI chr 9:23,658,574...23,684,240
Ensembl chr 9:23,658,574...23,684,240 		JBrowse link
G Gsta4 glutathione S-transferase alpha 4 multiple interactions
increases activity
increases expression		 EXP [Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein; [Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Maneb results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Maneb results in increased expression of GSTA4 mRNA]; Maneb results in increased expression of and results in increased activity of GSTA4 protein; Silymarin promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Silymarin promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Silymarin promotes the reaction [Maneb results in increased expression of and results in increased activity of GSTA4 protein]; Silymarin promotes the reaction [Maneb results in increased expression of GSTA4 mRNA]
Maneb results in increased activity of GSTA4 protein
Maneb results in increased expression of GSTA4 mRNA; Maneb results in increased expression of GSTA4 protein		 CTD PMID:20888808 PMID:23159886 NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182 		JBrowse link
G Gstp1 glutathione S-transferase pi 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of GSTP1 mRNA] CTD PMID:23963992 NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226 		JBrowse link
G Guk1 guanylate kinase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of GUK1 mRNA CTD PMID:18386188 NCBI chr10:43,971,514...43,988,658
Ensembl chr10:43,971,509...43,980,107 		JBrowse link
G H2ac20 H2A clustered histone 20 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of H2AC20 mRNA CTD PMID:22563483 NCBI chr 2:183,779,879...183,780,324 JBrowse link
G H2bc9 H2B clustered histone 9 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of H2BC9 mRNA CTD PMID:22563483 NCBI chr17:42,470,593...42,478,605 JBrowse link
G Hba-a1 hemoglobin alpha, adult chain 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HBA-A1 mRNA CTD PMID:18386188 NCBI chr10:15,337,265...15,338,121
Ensembl chr10:15,307,815...15,338,392 		JBrowse link
G Hdac3 histone deacetylase 3 decreases activity ISO Maneb results in decreased activity of HDAC3 protein CTD PMID:21251949 NCBI chr18:29,770,637...29,789,850
Ensembl chr18:29,770,636...29,793,856 		JBrowse link
G Hdac6 histone deacetylase 6 decreases activity ISO Maneb results in decreased activity of HDAC6 protein CTD PMID:21251949 NCBI chr  X:14,550,645...14,572,445
Ensembl chr  X:14,551,044...14,572,441 		JBrowse link
G Hes3 hes family bHLH transcription factor 3 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of HES3 mRNA CTD PMID:22563483 NCBI chr 5:162,793,611...162,799,578
Ensembl chr 5:162,794,367...162,796,261 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEY2 mRNA CTD PMID:23017109 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEYL mRNA CTD PMID:23017109 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Hk1 hexokinase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HK1 mRNA CTD PMID:18386188 NCBI chr20:30,230,488...30,332,161
Ensembl chr20:30,230,486...30,332,131 		JBrowse link
G Hmga2 high mobility group AT-hook 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HMGA2 mRNA CTD PMID:18386188 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgn5 high mobility group nucleosome binding domain 5 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of HMGN5 mRNA CTD PMID:22563483 NCBI chr  X:74,085,871...74,094,488 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 EXP
ISO		 Maneb results in increased expression of HMOX1 protein
[NFE2L2 gene mutant form results in increased susceptibility to Maneb] which results in decreased expression of HMOX1 protein		 CTD PMID:15527874 PMID:23764462 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpk heterogeneous nuclear ribonucleoprotein K multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of HNRNPK mRNA CTD PMID:18386188 NCBI chr17:6,262,936...6,275,001
Ensembl chr17:6,262,998...6,274,997 		JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 decreases activity ISO Maneb results in decreased activity of HSD11B2 protein CTD PMID:22796344 NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899 		JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSF1 mRNA] CTD PMID:23963992 NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA; [Paraquat co-treated with Maneb] results in increased expression of HSP90AA1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSP90AA1 mRNA] CTD PMID:18386188 PMID:23963992 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of HSPA1B mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of HSPA1B mRNA] CTD PMID:23963992 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of HSPA5 mRNA CTD PMID:18386188 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspa8 heat shock protein family A (Hsp70) member 8 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of HSPA8 mRNA CTD PMID:18386188 NCBI chr 8:41,183,397...41,187,260
Ensembl chr 8:41,183,264...41,187,259 		JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of ICAM1 mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ICAM1 mRNA] CTD PMID:32169474 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Icam2 intercellular adhesion molecule 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of ICAM2 mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ICAM2 mRNA] CTD PMID:32169474 NCBI chr10:91,308,608...91,319,536
Ensembl chr10:91,308,538...91,315,293 		JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of IDH3A protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IDH3A protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IDH3A protein] CTD PMID:23562983 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084 		JBrowse link
G Ier5l immediate early response 5-like multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of IER5L mRNA CTD PMID:22563483 NCBI chr 3:13,744,056...13,745,647
Ensembl chr 3:13,744,078...13,745,647 		JBrowse link
G Ifng interferon gamma multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of IFNG mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IFNG mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IFNG mRNA] CTD PMID:23963992 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of IGF1 mRNA] CTD PMID:23963992 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression		 EXP
ISO		 [Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]; Silymarin inhibits the reaction [Maneb results in increased expression of IL1B mRNA]
[Maneb co-treated with Paraquat] results in increased expression of IL1B mRNA; [Maneb co-treated with Paraquat] results in increased expression of IL1B protein; [Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA; [Paraquat co-treated with Maneb] results in increased expression of IL1B protein; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IL1B protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IL1B mRNA]; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of IL1B mRNA]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]		 CTD PMID:23159886 PMID:23963992 PMID:29568078 PMID:32169474 PMID:32375810 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of IL6 mRNA; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL6 mRNA] CTD PMID:32169474 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Inhba inhibin subunit beta A multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of INHBA mRNA; [Paraquat co-treated with Maneb] affects the expression of INHBA mRNA CTD PMID:22563483 PMID:23017109 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Irs2 insulin receptor substrate 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of IRS2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of IRS2 mRNA] CTD PMID:23963992 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Itgam integrin subunit alpha M multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of ITGAM protein; [Paraquat co-treated with Maneb] results in increased expression of ITGAM mRNA; [Paraquat co-treated with Maneb] results in increased expression of ITGAM protein; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of ITGAM protein]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ITGAM protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased cleavage of CASP1 protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of NLRP3 protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of ITGAM mRNA] CTD PMID:28202386 PMID:30797899 PMID:32169474 PMID:32375810 NCBI chr 1:182,659,047...182,709,495
Ensembl chr 1:182,659,000...182,709,503 		JBrowse link
G Itgb8 integrin subunit beta 8 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ITGB8 mRNA CTD PMID:22563483 NCBI chr 6:140,124,997...140,208,254
Ensembl chr 6:140,127,203...140,208,476 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of ITPR1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of ITPR1 mRNA] CTD PMID:23963992 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491 		JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of JPT1 mRNA CTD PMID:18386188 NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions EXP [Paraquat co-treated with Maneb] results in decreased expression of JUN mRNA; [Paraquat co-treated with Maneb] results in decreased expression of JUN protein; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of JUN mRNA]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of JUN protein] CTD PMID:27460631 PMID:33368748 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcna2 potassium voltage-gated channel subfamily A member 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of KCNA2 mRNA CTD PMID:22563483 NCBI chr 2:194,704,555...194,718,387
Ensembl chr 2:194,704,639...194,718,400 		JBrowse link
G Kcnma1 potassium calcium-activated channel subfamily M alpha 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of KCNMA1 mRNA CTD PMID:22563483 NCBI chr15:302,078...1,001,198
Ensembl chr15:302,214...1,001,198 		JBrowse link
G Kif1b kinesin family member 1B multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of KIF1B mRNA CTD PMID:22563483 NCBI chr 5:159,607,697...159,742,778
Ensembl chr 5:159,561,271...159,742,778 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase decreases expression EXP Maneb results in decreased expression of KIT CTD PMID:25803990 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Klf2 KLF transcription factor 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of KLF2 mRNA CTD PMID:22563483 NCBI chr16:17,521,773...17,523,723
Ensembl chr16:17,514,552...17,523,944 		JBrowse link
G Klhl15 kelch-like family member 15 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of KLHL15 mRNA CTD PMID:22563483 NCBI chr  X:58,994,726...59,050,207
Ensembl chr  X:58,995,461...59,046,069 		JBrowse link
G Lamc2 laminin subunit gamma 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of LAMC2 mRNA CTD PMID:22563483 NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lifr LIF receptor subunit alpha multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of LIFR mRNA CTD PMID:22563483 NCBI chr 2:56,224,393...56,292,988
Ensembl chr 2:56,250,120...56,286,699 		JBrowse link
G Limk2 LIM domain kinase 2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of LIMK2 mRNA CTD PMID:18386188 NCBI chr14:78,208,182...78,286,106
Ensembl chr14:78,218,063...78,286,007 		JBrowse link
G Loricrin loricrin cornified envelope precursor protein multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of LOR mRNA CTD PMID:22563483 NCBI chr 2:177,558,062...177,559,980
Ensembl chr 2:177,558,252...177,559,807 		JBrowse link
G Lrp4 LDL receptor related protein 4 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of LRP4 mRNA CTD PMID:22563483 NCBI chr 3:77,429,600...77,483,593
Ensembl chr 3:77,429,798...77,483,593 		JBrowse link
G Lrrc17 leucine rich repeat containing 17 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of LRRC17 mRNA CTD PMID:18386188 NCBI chr 4:13,501,428...13,531,845
Ensembl chr 4:13,501,436...13,531,845 		JBrowse link
G Lrrc41 leucine rich repeat containing 41 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of LRRC41 mRNA CTD PMID:18386188 NCBI chr 5:129,554,547...129,575,450
Ensembl chr 5:129,554,547...129,575,449 		JBrowse link
G Lrrk2 leucine-rich repeat kinase 2 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of ACHE mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CDK5R1 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CDK5RAP1 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of CHRM2 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of EFNB1 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of FEZ1 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEY2 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of NDP mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of NRG1 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of NTN1 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of PAX6 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of POU3F3 mRNA; [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of VEGFA mRNA; LRRK2 protein mutant form inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA]
3-(4-(morpholin-4-yl)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)benzonitrile inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of LRRK2 protein]; [Paraquat co-treated with Maneb] results in increased phosphorylation of LRRK2 protein; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of LRRK2 protein]; Plant Extracts inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of LRRK2 protein]		 CTD PMID:23017109 PMID:34897981 NCBI chr 7:122,826,712...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Lynx1 Ly6/neurotoxin 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of LYNX1 mRNA CTD PMID:18386188 NCBI chr 7:106,632,800...106,638,003
Ensembl chr 7:106,632,797...106,638,023 		JBrowse link
G Macf1 microtubule-actin crosslinking factor 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of MACF1 mRNA CTD PMID:18386188 NCBI chr 5:135,623,729...135,949,097
Ensembl chr 5:135,623,742...135,945,905 		JBrowse link
G Map2 microtubule-associated protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of MAP2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of MAP2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of MAP2 mRNA] CTD PMID:23963992 NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of MAP2K1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of MAP2K1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of MAP2K1 mRNA] CTD PMID:23963992 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map2k6 mitogen-activated protein kinase kinase 6 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of MAP2K6 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of MAP2K6 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of MAP2K6 mRNA] CTD PMID:23963992 NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK1 protein
[Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK1 protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK1 protein]		 CTD PMID:15824117 PMID:30797899 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk15 mitogen-activated protein kinase 15 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of MAPK15 mRNA CTD PMID:22563483 NCBI chr 7:107,694,907...107,714,640
Ensembl chr 7:107,694,964...107,714,645 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK3 protein
[Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK3 protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of MAPK3 protein]		 CTD PMID:15824117 PMID:30797899 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapt microtubule-associated protein tau multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of MAPT mRNA] CTD PMID:23963992 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Marchf9 membrane associated ring-CH-type finger 9 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of MARCHF9 mRNA CTD PMID:22563483 NCBI chr 7:62,879,017...62,882,495
Ensembl chr 7:62,879,018...62,882,495 		JBrowse link
G Mbd3 methyl-CpG binding domain protein 3 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of MBD3 mRNA; [Paraquat co-treated with Maneb] results in increased expression of MBD3 mRNA CTD PMID:18386188 NCBI chr 7:9,312,961...9,320,166
Ensembl chr 7:9,313,098...9,320,165 		JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of MBNL1 mRNA CTD PMID:18386188 NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368 		JBrowse link
G Mboat2 membrane bound O-acyltransferase domain containing 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of MBOAT2 mRNA CTD PMID:22563483 NCBI chr 6:41,471,135...41,597,599
Ensembl chr 6:41,471,161...41,593,485 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member increases expression
multiple interactions		 ISO Maneb results in increased expression of MCL1 protein
[Paraquat co-treated with Maneb] results in increased expression of MCL1 protein		 CTD PMID:18266926 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Mdm4 MDM4 regulator of p53 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of MDM4 mRNA CTD PMID:18386188 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Mef2c myocyte enhancer factor 2C multiple interactions ISO [Maneb promotes the reaction [SNCA gene mutant form results in increased susceptibility to Paraquat]] which results in increased metabolism of MEF2C protein; [Paraquat promotes the reaction [SNCA gene mutant form results in increased susceptibility to Maneb]] which results in increased metabolism of MEF2C protein CTD PMID:24290359 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mfge8 milk fat globule EGF and factor V/VIII domain containing multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of MFGE8 mRNA CTD PMID:18386188 NCBI chr 1:133,064,665...133,080,069
Ensembl chr 1:133,064,665...133,080,073 		JBrowse link
G Mrc1 mannose receptor, C type 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of MRC1 mRNA CTD PMID:29568078 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857 		JBrowse link
G Mrpl15 mitochondrial ribosomal protein L15 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of MRPL15 mRNA CTD PMID:18386188 NCBI chr 5:14,729,966...14,741,276
Ensembl chr 5:14,729,979...14,741,276 		JBrowse link
G Mrtfb myocardin related transcription factor B multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of MRTFB mRNA CTD PMID:22563483 NCBI chr10:1,116,315...1,278,106
Ensembl chr10:1,116,310...1,277,897 		JBrowse link
G Mthfr methylenetetrahydrofolate reductase multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of MTHFR mRNA CTD PMID:18386188 NCBI chr 5:158,465,248...158,484,999
Ensembl chr 5:158,465,296...158,483,797 		JBrowse link
G Mtor mechanistic target of rapamycin kinase multiple interactions
increases expression		 ISO [Paraquat co-treated with Maneb] results in increased expression of MTOR protein; Maneb promotes the reaction [Paraquat results in increased expression of MTOR protein]; Paraquat promotes the reaction [Maneb results in increased expression of MTOR protein] CTD PMID:22292029 PMID:26884967 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Muc6 mucin 6, oligomeric mucus/gel-forming multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of MUC6 mRNA CTD PMID:22563483 NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in increased expression of MYC protein CTD PMID:19883720 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO [Maneb co-treated with Paraquat] affects the localization of NCF1 protein; [Maneb co-treated with Paraquat] results in increased expression of NCF1 protein; [Paraquat co-treated with Maneb] results in increased expression of NCF1 protein; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NCF1 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NCF1 protein]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] affects the localization of NCF1 protein]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NCF1 protein] CTD PMID:28202386 PMID:29568078 PMID:32375810 PMID:34052309 NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646 		JBrowse link
G Ndp norrin cystine knot growth factor NDP multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of NDP mRNA CTD PMID:23017109 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Neurod1 neuronal differentiation 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of NEUROD1 mRNA CTD PMID:23017109 NCBI chr 3:64,360,222...64,363,526
Ensembl chr 3:64,359,395...64,363,649 		JBrowse link
G Nfat5 nuclear factor of activated T-cells 5 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of NFAT5 mRNA CTD PMID:22563483 NCBI chr19:35,199,737...35,286,675
Ensembl chr19:35,199,016...35,286,675 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
increases response to substance
multiple interactions		 ISO [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of GCLC mRNA; [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of NQO1 mRNA; [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of PRDX1 mRNA; [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of TXN1 mRNA; [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of TXNRD1 mRNA; Maneb results in increased expression of NFE2L2 protein
NFE2L2 gene mutant form results in increased susceptibility to Maneb
[NFE2L2 gene mutant form results in increased susceptibility to Maneb] which results in decreased abundance of Glutathione; [NFE2L2 gene mutant form results in increased susceptibility to Maneb] which results in decreased expression of GSR protein; [NFE2L2 gene mutant form results in increased susceptibility to Maneb] which results in decreased expression of HMOX1 protein; [NFE2L2 gene mutant form results in increased susceptibility to Maneb] which results in increased abundance of Manganese; [NFE2L2 gene mutant form results in increased susceptibility to Maneb] which results in increased abundance of Thiobarbituric Acid Reactive Substances; NFE2L2 gene mutant form inhibits the reaction [Maneb results in increased expression of GPX4 mRNA]		 CTD PMID:21402726 PMID:23764462 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfib nuclear factor I/B multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of NFIB mRNA CTD PMID:22563483 NCBI chr 5:96,759,208...96,973,092
Ensembl chr 5:96,764,653...96,975,479 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of NFKB1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NFKB1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NFKB1 mRNA] CTD PMID:23963992 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Maneb co-treated with Paraquat] results in increased phosphorylation of and results in decreased expression of NFKBIA protein; [Paraquat co-treated with Maneb] results in increased degradation of and results in increased phosphorylation of NFKBIA protein; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of and results in decreased expression of NFKBIA protein]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased degradation of and results in increased phosphorylation of NFKBIA protein] CTD PMID:28202386 PMID:29568078 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nipbl NIPBL, cohesin loading factor multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of NIPBL mRNA CTD PMID:22563483 NCBI chr 2:57,399,443...57,586,770
Ensembl chr 2:57,399,445...57,565,899 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of NLRP3 protein; [Paraquat co-treated with Maneb] results in increased expression of NLRP3 protein; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NLRP3 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NLRP3 protein]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of NLRP3 protein] CTD PMID:32375810 PMID:34052309 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nog noggin multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of NOG mRNA CTD PMID:23017109 NCBI chr10:74,128,712...74,130,339
Ensembl chr10:74,128,712...74,130,339 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions
increases expression		 ISO
EXP		 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; [Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA; [Maneb co-treated with Paraquat] results in increased expression of NOS2 protein; [Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA; [Paraquat co-treated with Maneb] results in increased expression of NOS2 protein; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Genistein inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA]; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 protein]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA]; pimagedine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; prolinedithiocarbamate inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of NOS2 mRNA]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]
[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Silymarin inhibits the reaction [Maneb results in increased expression of NOS2 mRNA]		 CTD PMID:20455021 PMID:23159886 PMID:23963992 PMID:28202386 PMID:29568078 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nox1 NADPH oxidase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of NOX1 mRNA; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX1 mRNA]; diphenyleneiodonium inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOX1 mRNA] CTD PMID:30797899 NCBI chr  X:97,279,058...97,332,291
Ensembl chr  X:97,279,056...97,302,236 		JBrowse link
G Nps neuropeptide S multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of NPS mRNA CTD PMID:22563483 NCBI chr 1:190,077,040...190,080,821
Ensembl chr 1:190,077,040...190,080,821 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 increases expression ISO [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of NQO1 mRNA CTD PMID:21402726 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr4a1 nuclear receptor subfamily 4, group A, member 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of NR4A1 mRNA CTD PMID:22563483 NCBI chr 7:132,368,399...132,389,300
Ensembl chr 7:132,374,840...132,389,297 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 multiple interactions EXP [Paraquat co-treated with Maneb] results in decreased expression of NR4A2 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of NR4A2 protein CTD PMID:29152652 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nrg1 neuregulin 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of NRG1 mRNA CTD PMID:23017109 NCBI chr16:59,250,658...60,303,024
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrtn neurturin multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of NRTN mRNA CTD PMID:22563483 NCBI chr 9:1,581,860...1,587,835
Ensembl chr 9:1,581,975...1,583,102 		JBrowse link
G Ntn1 netrin 1 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of NTN1 mRNA; [Maneb co-treated with Paraquat] results in decreased expression of NTN1 mRNA CTD PMID:23017109 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of NTRK2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of NTRK2 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of NTRK2 mRNA] CTD PMID:23963992 NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Oaz2 ornithine decarboxylase antizyme 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of OAZ2 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of OAZ2 mRNA] CTD PMID:23963992 NCBI chr 8:66,199,694...66,213,513
Ensembl chr 8:66,199,706...66,231,453 		JBrowse link
G P2ry4 pyrimidinergic receptor P2Y4 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of P2RY4 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of P2RY4 mRNA] CTD PMID:23963992 NCBI chr  X:65,681,680...65,717,404
Ensembl chr  X:65,683,232...65,721,748 		JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO 3-(4-(morpholin-4-yl)-7H-pyrrolo(2,3-d)pyrimidin-5-yl)benzonitrile inhibits the reaction [[Paraquat co-treated with Maneb] results in increased oxidation of PARK7 protein]; [Paraquat co-treated with Maneb] results in increased oxidation of PARK7 protein; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased oxidation of PARK7 protein]; Plant Extracts inhibits the reaction [[Paraquat co-treated with Maneb] results in increased oxidation of PARK7 protein] CTD PMID:34897981 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970 		JBrowse link
G Pax5 paired box 5 multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of PAX5 mRNA CTD PMID:23017109 NCBI chr 5:58,763,334...58,945,719
Ensembl chr 5:58,765,036...58,944,326 		JBrowse link
G Pax6 paired box 6 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of PAX6 mRNA CTD PMID:23017109 NCBI chr 3:92,128,772...92,157,022
Ensembl chr 3:92,135,637...92,157,014 		JBrowse link
G Pcdh7 protocadherin 7 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of PCDH7 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of PCDH7 mRNA] CTD PMID:23963992 NCBI chr14:52,471,801...52,901,696
Ensembl chr14:52,475,610...52,902,051
Ensembl chr14:52,475,610...52,902,051 		JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of PCNA protein]; [Paraquat co-treated with Maneb] results in decreased expression of PCNA protein CTD PMID:23985028 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pcp2 Purkinje cell protein 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of PCP2 mRNA CTD PMID:22563483 NCBI chr12:1,681,659...1,683,899
Ensembl chr12:1,681,659...1,683,899 		JBrowse link
G Pdcd10 programmed cell death 10 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of PDCD10 mRNA CTD PMID:18386188 NCBI chr 2:160,303,465...160,346,086
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Pde1b phosphodiesterase 1B multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of PDE1B mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PDE1B mRNA] CTD PMID:23963992 NCBI chr 7:134,627,378...134,654,581
Ensembl chr 7:134,627,322...134,654,580 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of PDGFRA mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of PDGFRA mRNA] CTD PMID:23963992 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdha1 pyruvate dehydrogenase E1 subunit alpha 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of PDHA1 mRNA; [Maneb co-treated with Paraquat] results in increased expression of PDHA1 protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of PDHA1 protein]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PDHA1 mRNA] CTD PMID:23562983 PMID:23963992 NCBI chr  X:34,700,481...34,714,309
Ensembl chr  X:34,700,409...34,714,311 		JBrowse link
G Pdyn prodynorphin multiple interactions EXP [Paraquat co-treated with Maneb] results in decreased expression of PDYN CTD PMID:24376148 NCBI chr 3:116,900,990...116,913,334
Ensembl chr 3:116,900,992...116,913,334 		JBrowse link
G Pebp1 phosphatidylethanolamine binding protein 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of PEBP1 protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PEBP1 protein] CTD PMID:23562983 NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862 		JBrowse link
G Pgs1 phosphatidylglycerophosphate synthase 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of PGS1 mRNA CTD PMID:18386188 NCBI chr10:103,214,635...103,250,254
Ensembl chr10:103,214,646...103,250,254 		JBrowse link
G Pigc phosphatidylinositol glycan anchor biosynthesis, class C multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of PIGC mRNA CTD PMID:18386188 NCBI chr13:74,343,619...74,346,148
Ensembl chr13:74,296,854...74,346,211 		JBrowse link
G Plce1 phospholipase C, epsilon 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of PLCE1 mRNA CTD PMID:22563483 NCBI chr 1:236,243,445...236,552,571
Ensembl chr 1:236,244,683...236,551,438 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression ISO Maneb results in increased expression of PMAIP1 mRNA; Maneb results in increased expression of PMAIP1 protein CTD PMID:18266926 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Pnoc prepronociceptin multiple interactions EXP [Paraquat co-treated with Maneb] results in increased expression of PNOC CTD PMID:24376148 NCBI chr15:39,624,635...39,652,463
Ensembl chr15:39,624,641...39,651,867 		JBrowse link
G Polr1c RNA polymerase I and III subunit C multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of POLR1C mRNA CTD PMID:18386188 NCBI chr 9:14,735,740...14,739,852
Ensembl chr 9:14,735,714...14,739,852 		JBrowse link
G Polr2k RNA polymerase II, I and III subunit K multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of POLR2K mRNA CTD PMID:22563483 NCBI chr 7:67,347,118...67,359,466
Ensembl chr 7:67,356,113...67,357,668 		JBrowse link
G Pou3f3 POU class 3 homeobox 3 multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of POU3F3 mRNA CTD PMID:23017109 NCBI chr 9:44,945,872...44,948,986
Ensembl chr 9:44,945,872...44,948,992 		JBrowse link
G Prdx1 peroxiredoxin 1 increases expression ISO [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of PRDX1 mRNA CTD PMID:21402726 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856 		JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of PRDX3 protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PRDX3 protein]; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PRDX3 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PRDX3 protein] CTD PMID:23562983 NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha multiple interactions EXP [Paraquat co-treated with Maneb] results in decreased expression of PRKACA mRNA; [Paraquat co-treated with Maneb] results in decreased expression of PRKACA protein; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of PRKACA mRNA] CTD PMID:27460631 PMID:33368748 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkcz protein kinase C, zeta multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of PRKCZ mRNA CTD PMID:18386188 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase multiple interactions ISO 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased nitrosation of PRKN protein]; [Paraquat co-treated with Maneb] results in increased expression of PRKN protein; [Paraquat co-treated with Maneb] results in increased nitrosation of PRKN protein CTD PMID:22563483 PMID:23985028 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Prl prolactin multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of PRL mRNA CTD PMID:22563483 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062 		JBrowse link
G Prr7 proline rich 7 (synaptic) multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of PRR7 mRNA CTD PMID:22563483 NCBI chr17:9,164,375...9,173,669
Ensembl chr17:9,165,269...9,172,536 		JBrowse link
G Psap prosaposin multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of PSAP mRNA CTD PMID:18386188 NCBI chr20:28,214,229...28,240,501
Ensembl chr20:28,214,271...28,240,498 		JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of PSEN1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of PSEN1 mRNA] CTD PMID:23963992 NCBI chr 6:103,323,014...103,375,088
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Psmb1 proteasome 20S subunit beta 1 multiple interactions ISO Maneb inhibits the reaction [Paraquat results in decreased expression of PSMB1 mRNA] CTD PMID:26498265 NCBI chr 1:56,442,432...56,463,544
Ensembl chr 1:56,420,618...56,463,560 		JBrowse link
G Psmc4 proteasome 26S subunit, ATPase 4 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of PSMC4 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of PSMC4 mRNA]
[Paraquat co-treated with Maneb] results in decreased expression of PSMC4 mRNA		 CTD PMID:23963992 PMID:26498265 NCBI chr 1:83,349,127...83,357,497
Ensembl chr 1:83,348,592...83,357,494 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta multiple interactions ISO [alachlor co-treated with Captan co-treated with Diazinon co-treated with Endosulfan co-treated with mancozeb co-treated with Maneb] results in decreased expression of PTK2B protein modified form CTD PMID:19883720 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ptpn4 protein tyrosine phosphatase, non-receptor type 4 affects activity ISO Maneb affects the activity of PTPN4 protein CTD PMID:23611293 NCBI chr13:30,772,012...30,952,340
Ensembl chr13:30,776,682...30,952,170 		JBrowse link
G Ptpn9 protein tyrosine phosphatase, non-receptor type 9 affects activity ISO Maneb affects the activity of PTPN9 protein CTD PMID:23611293 NCBI chr 8:57,391,290...57,472,352
Ensembl chr 8:57,391,259...57,470,952 		JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of RAF1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of RAF1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of RAF1 mRNA] CTD PMID:23963992 NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317 		JBrowse link
G Rb1 RB transcriptional corepressor 1 multiple interactions
increases expression		 EXP [Maneb co-treated with Paraquat] results in increased expression of RB1 mRNA; Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of RB1 mRNA]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of RB1 mRNA] CTD PMID:29859004 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Rbx1 ring-box 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RBX1 mRNA CTD PMID:18386188 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Maneb co-treated with Paraquat] results in increased phosphorylation of RELA protein; [Paraquat co-treated with Maneb] results in increased phosphorylation of RELA protein; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of RELA protein]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of RELA protein] CTD PMID:28202386 PMID:29568078 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of RIPK1 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of RIPK1 mRNA] CTD PMID:23963992 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ROCK1 mRNA CTD PMID:22563483 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rpl12 ribosomal protein L12 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RPL12 mRNA CTD PMID:18386188 NCBI chr 3:16,264,269...16,266,645
Ensembl chr 3:16,264,251...16,266,642 		JBrowse link
G Rpl19 ribosomal protein L19 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of RPL19 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of RPL19 mRNA] CTD PMID:23963992 NCBI chr10:83,022,503...83,026,030
Ensembl chr10:83,019,257...83,052,112 		JBrowse link
G Rpl41 ribosomal protein L41 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RPL41 mRNA CTD PMID:18386188 NCBI chr 7:977,885...978,965 JBrowse link
G Rpl8 ribosomal protein L8 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RPL8 mRNA CTD PMID:18386188 NCBI chr 7:108,626,194...108,628,485
Ensembl chr 7:108,622,324...108,628,482 		JBrowse link
G Rpl9 ribosomal protein L9 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RPL9 mRNA CTD PMID:18386188 NCBI chr14:42,893,945...42,897,140
Ensembl chr14:42,893,942...42,897,136 		JBrowse link
G Rps12 ribosomal protein S12 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RPS12 mRNA CTD PMID:18386188 NCBI chr 1:21,680,854...21,683,010
Ensembl chr 1:21,680,852...21,683,014 		JBrowse link
G Rps15 ribosomal protein S15 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RPS15 mRNA CTD PMID:18386188 NCBI chr 7:9,416,003...9,417,442
Ensembl chr 7:9,416,004...9,417,450 		JBrowse link
G Rps27 ribosomal protein S27 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RPS27 mRNA CTD PMID:18386188 NCBI chr 2:175,665,858...175,666,963
Ensembl chr 2:175,665,853...175,666,964 		JBrowse link
G Rps6ka2 ribosomal protein S6 kinase A2 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of RPS6KA2 mRNA CTD PMID:18386188 NCBI chr 1:52,631,582...52,906,739
Ensembl chr 1:52,631,736...52,906,739 		JBrowse link
G Rtn4 reticulon 4 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of RTN4 mRNA CTD PMID:23017109 NCBI chr14:103,450,074...103,497,687
Ensembl chr14:103,449,930...103,497,686 		JBrowse link
G Rtn4rl2 reticulon 4 receptor-like 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of RTN4RL2 mRNA CTD PMID:22563483 NCBI chr 3:69,954,557...69,971,108
Ensembl chr 3:69,955,169...69,971,488 		JBrowse link
G S100a8 S100 calcium binding protein A8 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of S100A8 mRNA CTD PMID:22563483 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S100a9 S100 calcium binding protein A9 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of S100A9 mRNA CTD PMID:22563483 NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230 		JBrowse link
G Scamp2 secretory carrier membrane protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of SCAMP2 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SCAMP2 mRNA] CTD PMID:23963992 NCBI chr 8:57,965,612...57,992,248
Ensembl chr 8:57,965,631...57,992,646 		JBrowse link
G Scand1 SCAN domain-containing 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of SCAND1 mRNA CTD PMID:22563483 NCBI chr 3:144,818,615...144,819,479
Ensembl chr 3:144,818,611...144,820,025 		JBrowse link
G Sdhb succinate dehydrogenase complex iron sulfur subunit B multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of SDHB mRNA CTD PMID:18386188 NCBI chr 5:153,264,906...153,285,570
Ensembl chr 5:153,264,899...153,314,293 		JBrowse link
G Sema4d semaphorin 4D multiple interactions ISO [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of SEMA4D mRNA CTD PMID:23017109 NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138 		JBrowse link
G Sirt1 sirtuin 1 decreases activity ISO Maneb results in decreased activity of SIRT1 protein CTD PMID:21251949 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Sirt2 sirtuin 2 decreases activity ISO Maneb results in decreased activity of SIRT2 protein CTD PMID:21251949 NCBI chr 1:84,053,883...84,076,975
Ensembl chr 1:84,052,903...84,076,975 		JBrowse link
G Sirt3 sirtuin 3 decreases activity ISO Maneb results in decreased activity of SIRT3 protein CTD PMID:21251949 NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808 		JBrowse link
G Slc17a8 solute carrier family 17 member 8 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of SLC17A8 mRNA CTD PMID:22563483 NCBI chr 7:23,994,212...24,049,498
Ensembl chr 7:23,994,217...24,048,079 		JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions
decreases expression		 ISO [Paraquat co-treated with Maneb] results in decreased expression of SLC18A2 mRNA; Ketoconazole inhibits the reaction [Maneb results in decreased expression of SLC18A2 protein]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of SLC18A2 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of SLC18A2 mRNA] CTD PMID:18386188 PMID:20964710 PMID:22334051 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325 		JBrowse link
G Slc22a2 solute carrier family 22 member 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of SLC22A2 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SLC22A2 mRNA] CTD PMID:23963992 NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268 		JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of SLC40A1 protein; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of SLC40A1 protein] CTD PMID:30797899 NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481 		JBrowse link
G Slc5a7 solute carrier family 5 member 7 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of SLC5A7 mRNA CTD PMID:22563483 NCBI chr 9:7,595,440...7,626,258
Ensembl chr 9:7,595,444...7,626,258 		JBrowse link
G Slc6a2 solute carrier family 6 member 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of SLC6A2 mRNA CTD PMID:22563483 NCBI chr19:14,010,292...14,055,317
Ensembl chr19:14,010,386...14,050,357 		JBrowse link
G Slc6a3 solute carrier family 6 member 3 multiple interactions
affects response to substance		 ISO [Paraquat co-treated with Maneb] results in decreased expression of SLC6A3 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of SLC6A3 protein
SLC6A3 gene polymorphism affects the susceptibility to Maneb		 CTD PMID:11124998 PMID:18386188 PMID:19590691 NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413 		JBrowse link
G Slc8a1 solute carrier family 8 member A1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of SLC8A1 mRNA CTD PMID:22563483 NCBI chr 6:13,194,609...13,547,369
Ensembl chr 6:13,194,662...13,535,628 		JBrowse link
G Snca synuclein alpha multiple interactions
increases response to substance		 ISO [Maneb co-treated with Paraquat] results in increased phosphorylation of SNCA protein; [Paraquat co-treated with Maneb] promotes the reaction [SNCA protein binds to SNCA protein]; [Paraquat co-treated with Maneb] results in increased expression of SNCA protein; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ADORA1 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of APBB1 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ASCL1 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP2 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of BMP4 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DLL1 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DRD2 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of DRD5 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of HEYL mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of PAX5 mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of SEMA4D mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of VEGFA mRNA; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased phosphorylation of SNCA protein]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] promotes the reaction [SNCA protein binds to SNCA protein]]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of SNCA protein]; SNCA protein inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of CDK5RAP2 mRNA]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] promotes the reaction [SNCA protein binds to SNCA protein]]
SNCA gene mutant form results in increased susceptibility to Maneb
[Maneb promotes the reaction [SNCA gene mutant form results in increased susceptibility to Paraquat]] which results in increased abundance of Nitric Oxide; [Maneb promotes the reaction [SNCA gene mutant form results in increased susceptibility to Paraquat]] which results in increased metabolism of MEF2C protein; [Paraquat promotes the reaction [SNCA gene mutant form results in increased susceptibility to Maneb]] which results in increased abundance of Nitric Oxide; [Paraquat promotes the reaction [SNCA gene mutant form results in increased susceptibility to Maneb]] which results in increased metabolism of MEF2C protein; Maneb promotes the reaction [Paraquat results in increased expression of SNCA protein]; Maneb promotes the reaction [SNCA gene mutant form results in increased susceptibility to Paraquat]; Paraquat promotes the reaction [SNCA gene mutant form results in increased susceptibility to Maneb]; SNCA protein mutant form results in increased susceptibility to [Paraquat co-treated with Maneb]; SNCA protein results in increased susceptibility to [Maneb co-treated with Paraquat]		 CTD PMID:23017109 PMID:24290359 PMID:26498265 PMID:27324791 PMID:29568078 More... NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO
EXP		 SOD1 protein results in decreased susceptibility to [Paraquat co-treated with Maneb]
[Maneb co-treated with Paraquat] results in increased expression of SOD1 mRNA
[Paraquat co-treated with Maneb] results in decreased expression of SOD1 mRNA		 CTD PMID:15824117 PMID:18386188 PMID:29859004 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression		 ISO [Maneb co-treated with Paraquat] results in decreased expression of SOD2 protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SOD2 protein]; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SOD2 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SOD2 protein]
Maneb results in decreased expression of SOD2 mRNA		 CTD PMID:23562983 PMID:26210702 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT3 mRNA] CTD PMID:23963992 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of STAT4 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT4 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STAT4 mRNA] CTD PMID:23963992 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stmn1 stathmin 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of STMN1 protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STMN1 protein]; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STMN1 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of STMN1 protein] CTD PMID:23562983 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Ston2 stonin 2 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of STON2 mRNA CTD PMID:22563483 NCBI chr 6:110,567,485...110,676,376
Ensembl chr 6:110,567,485...110,676,376 		JBrowse link
G Strbp spermatid perinuclear RNA binding protein multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of STRBP mRNA CTD PMID:22563483 NCBI chr 3:21,328,310...21,467,753
Ensembl chr 3:21,337,855...21,414,949 		JBrowse link
G Sumo1 small ubiquitin-like modifier 1 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of SUMO1 mRNA CTD PMID:18386188 NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761 		JBrowse link
G Syt5 synaptotagmin 5 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of SYT5 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SYT5 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of SYT5 mRNA] CTD PMID:23963992 NCBI chr 1:69,277,351...69,285,071
Ensembl chr 1:69,277,351...69,285,067 		JBrowse link
G Tbck TBC1 domain containing kinase multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of TBCK mRNA CTD PMID:22563483 NCBI chr 2:221,175,749...221,348,126
Ensembl chr 2:221,175,785...221,348,126 		JBrowse link
G Tecr trans-2,3-enoyl-CoA reductase multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of TECR mRNA CTD PMID:18386188 NCBI chr19:24,526,705...24,568,168
Ensembl chr19:24,541,615...24,568,168 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of TGFB1 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TGFB1 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TGFB1 mRNA] CTD PMID:23963992 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Th tyrosine hydroxylase multiple interactions
decreases expression		 ISO
EXP		 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein]; [Paraquat co-treated with Maneb] results in decreased expression of TH protein; [Paraquat co-treated with Maneb] results in increased expression of TH protein; Genistein inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein]; Ketoconazole inhibits the reaction [Maneb results in decreased expression of TH protein]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of TH protein]; pimagedine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein]; prolinedithiocarbamate inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TH protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of TH protein]
[Paraquat co-treated with Maneb] results in decreased expression of TH; [Paraquat co-treated with Maneb] results in decreased expression of TH mRNA; [Paraquat co-treated with Maneb] results in decreased expression of TH protein		 CTD PMID:11124998 PMID:18386188 PMID:20455021 PMID:20964710 PMID:22334051 More... NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767 		JBrowse link
G Timm13 translocase of inner mitochondrial membrane 13 multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of TIMM13 mRNA CTD PMID:18386188 NCBI chr 7:8,809,069...8,810,172
Ensembl chr 7:8,809,058...8,809,910 		JBrowse link
G Tmem42 transmembrane protein 42 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of TMEM42 mRNA CTD PMID:22563483 NCBI chr 8:122,674,793...122,677,290
Ensembl chr 8:122,674,070...122,677,276 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP
ISO		 Maneb results in increased expression of TNF mRNA
[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA; [Paraquat co-treated with Maneb] results in increased expression of TNF mRNA; acetovanillone inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; acetovanillone inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; Glyburide inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; ITGAM protein affects the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; Poloxamer inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNF mRNA]; Taurine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]
[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [Maneb results in increased expression of TNF mRNA]		 CTD PMID:23159886 PMID:23963992 PMID:28202386 PMID:29568078 PMID:30797899 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of TNFAIP3 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TNFAIP3 mRNA] CTD PMID:23963992 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnr tenascin R multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of TNR mRNA CTD PMID:23017109 NCBI chr13:71,751,714...72,172,731
Ensembl chr13:72,091,585...72,167,641 		JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TRP53 protein]; [Maneb co-treated with Paraquat] results in increased expression of TRP53 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of TRP53 protein; [Paraquat co-treated with Maneb] results in increased activity of TRP53 protein modified form; [Paraquat co-treated with Maneb] results in increased expression of TRP53 protein; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TRP53 mRNA]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of TRP53 protein]; Melatonin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of TRP53 protein modified form]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TRP53 mRNA]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in decreased expression of TRP53 protein]; Silymarin inhibits the reaction [[Paraquat co-treated with Maneb] results in increased activity of TRP53 protein modified form] CTD PMID:20964710 PMID:23963992 PMID:23985028 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of ACT1 protein CTD PMID:23562983 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of TRAF6 mRNA; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TRAF6 mRNA] CTD PMID:23963992 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trpm3 transient receptor potential cation channel, subfamily M, member 3 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of TRPM3 mRNA CTD PMID:22563483 NCBI chr 1:219,673,200...220,557,610
Ensembl chr 1:219,672,892...220,560,717 		JBrowse link
G Tuba1a tubulin, alpha 1A multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of TUBA1A protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TUBA1A protein]; Minocycline inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TUBA1A protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of TUBA1A protein] CTD PMID:23562983 NCBI chr 7:130,113,214...130,116,880
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tuba1b tubulin, alpha 1B multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of TUBA1B mRNA CTD PMID:18386188 NCBI chr 7:130,090,669...130,093,644
Ensembl chr 7:130,081,032...130,196,186 		JBrowse link
G Tubb5 tubulin, beta 5 class I multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of TUBB5 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of TUBB5 mRNA] CTD PMID:23963992 NCBI chr20:2,912,779...2,916,928
Ensembl chr20:2,912,778...2,916,940 		JBrowse link
G Tusc1 tumor suppressor candidate 1 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of TUSC1 mRNA CTD PMID:22563483 NCBI chr 5:108,089,952...108,091,636
Ensembl chr 5:108,090,613...108,091,224 		JBrowse link
G Txn1 thioredoxin 1 increases expression ISO [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of TXN1 mRNA CTD PMID:21402726 NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression ISO [Maneb results in increased expression of NFE2L2 protein] which results in increased expression of TXNRD1 mRNA CTD PMID:21402726 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863 		JBrowse link
G Uba1 ubiquitin-like modifier activating enzyme 1 multiple interactions ISO Maneb results in decreased activity of and results in decreased ubiquitination of UBA1 protein CTD PMID:25714994 NCBI chr  X:1,508,700...1,530,677
Ensembl chr  X:1,508,666...1,530,636 		JBrowse link
G Ubb ubiquitin B multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of UBB mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of UBB mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of UBB mRNA] CTD PMID:23963992 NCBI chr10:47,247,629...47,249,335
Ensembl chr10:47,245,637...47,249,333 		JBrowse link
G Ubc ubiquitin C multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of UBC mRNA CTD PMID:18386188 NCBI chr12:31,238,889...31,243,924
Ensembl chr12:31,239,152...31,243,925 		JBrowse link
G Ubxn7 UBX domain protein 7 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of UBXN7 mRNA CTD PMID:22563483 NCBI chr11:68,427,896...68,460,100 JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of UCHL1 protein; [Paraquat co-treated with Maneb] results in decreased expression of UCHL1 mRNA CTD PMID:18386188 PMID:23562983 NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590 		JBrowse link
G Uchl5 ubiquitin C-terminal hydrolase L5 multiple interactions ISO [Paraquat co-treated with Maneb] results in increased expression of UCHL5 mRNA CTD PMID:18386188 NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502 		JBrowse link
G Unc13c unc-13 homolog C multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of UNC13C mRNA CTD PMID:22563483 NCBI chr 8:74,247,026...74,697,629
Ensembl chr 8:74,247,899...74,673,223 		JBrowse link
G Upf3b UPF3B, regulator of nonsense mediated mRNA decay multiple interactions ISO [Paraquat co-treated with Maneb] results in decreased expression of UPF3B mRNA CTD PMID:18386188 NCBI chr  X:116,335,308...116,353,332
Ensembl chr  X:116,335,308...116,353,236 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 multiple interactions ISO [Maneb co-treated with Paraquat] results in increased expression of UQCRC1 protein; Levodopa inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of UQCRC1 protein]; tetrakis(N-methyl-4-pyridiniumyl)porphine manganese(III) complex inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of UQCRC1 protein] CTD PMID:23562983 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480 		JBrowse link
G Vamp5 vesicle-associated membrane protein 5 multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of VAMP5 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of VAMP5 mRNA]; Silymarin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of VAMP5 mRNA] CTD PMID:23963992 NCBI chr 4:104,423,813...104,435,059
Ensembl chr 4:104,423,820...104,426,212 		JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO [LRRK2 protein mutant form co-treated with Maneb co-treated with Paraquat] results in decreased expression of VEGFA mRNA; [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of VEGFA mRNA CTD PMID:23017109 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vps45 vacuolar protein sorting 45 homolog multiple interactions ISO [Maneb co-treated with Paraquat] results in decreased expression of VPS45 mRNA; Melatonin inhibits the reaction [[Maneb co-treated with Paraquat] results in decreased expression of VPS45 mRNA] CTD PMID:23963992 NCBI chr 2:183,555,919...183,616,312
Ensembl chr 2:183,555,921...183,616,295 		JBrowse link
G Wnt1 Wnt family member 1 multiple interactions EXP [Paraquat co-treated with Maneb] results in decreased expression of WNT1 mRNA; [Paraquat co-treated with Maneb] results in decreased expression of WNT1 protein CTD PMID:29152652 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wnt5a Wnt family member 5A multiple interactions EXP [Paraquat co-treated with Maneb] results in increased expression of WNT5A mRNA; [Paraquat co-treated with Maneb] results in increased expression of WNT5A protein CTD PMID:29152652 NCBI chr16:3,695,667...3,718,234
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zbtb44 zinc finger and BTB domain containing 44 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ZBTB44 mRNA CTD PMID:22563483 NCBI chr 8:29,466,055...29,524,027
Ensembl chr 8:29,466,352...29,518,163 		JBrowse link
G Zfp580 zinc finger protein 580 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ZFP580 mRNA CTD PMID:22563483 NCBI chr 1:68,787,118...68,789,286
Ensembl chr 1:68,787,118...68,789,286 		JBrowse link
G Zhx3 zinc fingers and homeoboxes 3 multiple interactions ISO [Paraquat co-treated with Maneb] affects the expression of ZHX3 mRNA CTD PMID:22563483 NCBI chr 3:149,417,843...149,548,671
Ensembl chr 3:149,417,818...149,527,079 		JBrowse link
manganese(II) chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca5 ATP binding cassette subfamily A member 5 decreases expression ISO manganese chloride results in decreased expression of ABCA5 mRNA CTD PMID:17175027 NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976 		JBrowse link
G Abca9 ATP binding cassette subfamily A member 9 increases expression ISO manganese chloride results in increased expression of ABCA9 mRNA CTD PMID:17175027 NCBI chr10:95,077,615...95,137,751
Ensembl chr10:95,079,058...95,139,608 		JBrowse link
G Abcb1a ATP binding cassette subfamily B member 1A increases expression EXP manganese chloride results in increased expression of ABCB1A mRNA CTD PMID:26745496 NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709 		JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B increases expression EXP manganese chloride results in increased expression of ABCB1B mRNA CTD PMID:28801915 NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199 		JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 increases expression
decreases methylation		 EXP manganese chloride results in increased expression of ABCC2 mRNA
manganese chloride results in decreased methylation of ABCC2 gene		 CTD PMID:28801915 NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238 		JBrowse link
G Abcc8 ATP binding cassette subfamily C member 8 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in increased expression of ABCC8 protein CTD PMID:32659473 NCBI chr 1:96,598,663...96,679,495
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Abi2 abl-interactor 2 increases expression ISO manganese chloride results in increased expression of ABI2 mRNA CTD PMID:17175027 NCBI chr 9:61,856,379...61,904,029
Ensembl chr 9:61,827,139...61,905,699 		JBrowse link
G Abitram actin binding transcription modulator increases expression EXP manganese chloride results in increased expression of ABITRAM mRNA CTD PMID:28801915 NCBI chr 5:71,505,853...71,524,224
Ensembl chr 5:71,505,813...71,511,890 		JBrowse link
G Acap1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1 increases expression EXP manganese chloride results in increased expression of ACAP1 mRNA CTD PMID:28801915 NCBI chr10:54,605,323...54,619,472
Ensembl chr10:54,605,323...54,619,472 		JBrowse link
G Ace angiotensin I converting enzyme increases expression EXP manganese chloride results in increased expression of ACE mRNA CTD PMID:28801915 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ache acetylcholinesterase increases activity
increases expression
multiple interactions
decreases activity		 EXP
ISO		 manganese chloride results in increased activity of ACHE protein
manganese chloride results in increased expression of ACHE mRNA
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased activity of ACHE protein]; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein]; Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Silymarin inhibits the reaction [manganese chloride results in increased expression of ACHE mRNA]
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased activity of ACHE protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of ACHE mRNA alternative form		 CTD PMID:20503066 PMID:22033861 PMID:22154916 PMID:22192907 PMID:30738988 More... NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651 		JBrowse link
G Aco1 aconitase 1 increases activity EXP manganese chloride results in increased activity of ACO1 protein CTD PMID:15893546 PMID:16545456 PMID:16568477 NCBI chr 5:55,259,841...55,315,872
Ensembl chr 5:55,259,827...55,316,391 		JBrowse link
G Aco2 aconitase 2 multiple interactions
decreases expression
decreases activity		 ISO
EXP		 ferric ammonium citrate inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]
manganese chloride results in decreased expression of ACO2 mRNA; manganese chloride results in decreased expression of ACO2 protein
Iron inhibits the reaction [manganese chloride results in decreased activity of ACO2 protein]		 CTD PMID:9675333 PMID:16625280 NCBI chr 7:113,385,677...113,428,794
Ensembl chr 7:113,385,646...113,428,261 		JBrowse link
G Acot2 acyl-CoA thioesterase 2 increases expression EXP manganese chloride results in increased expression of ACOT2 mRNA CTD PMID:28801915 NCBI chr 6:103,611,744...103,619,404
Ensembl chr 6:103,611,544...103,619,245 		JBrowse link
G Acp5 acid phosphatase 5, tartrate resistant increases expression
increases methylation		 EXP manganese chloride results in increased expression of ACP5 mRNA
manganese chloride results in increased methylation of ACP5 gene		 CTD PMID:22281203 PMID:28801915 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929 		JBrowse link
G Acr acrosin increases expression EXP manganese chloride results in increased expression of ACR mRNA CTD PMID:28801915 NCBI chr 7:120,636,581...120,644,474
Ensembl chr 7:120,638,321...120,644,474 		JBrowse link
G Acsl3 acyl-CoA synthetase long-chain family member 3 decreases expression ISO manganese chloride results in decreased expression of ACSL3 mRNA CTD PMID:15295902 NCBI chr 9:80,140,996...80,164,636
Ensembl chr 9:80,115,112...80,164,627 		JBrowse link
G Acss2 acyl-CoA synthetase short-chain family member 2 decreases expression EXP manganese chloride results in decreased expression of ACSS2 mRNA CTD PMID:28801915 NCBI chr 3:144,003,808...144,047,452
Ensembl chr 3:144,004,336...144,059,675 		JBrowse link
G Acta1 actin, alpha 1, skeletal muscle decreases expression EXP manganese chloride results in decreased expression of ACTA1 mRNA CTD PMID:26745496 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression EXP manganese chloride results in increased expression of ACTA2 mRNA CTD PMID:28801915 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actb actin, beta decreases expression
increases expression		 ISO manganese chloride results in decreased expression of ACTB protein
manganese chloride results in increased expression of ACTB mRNA		 CTD PMID:20452446 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Acvrl1 activin A receptor like type 1 increases expression EXP manganese chloride results in increased expression of ACVRL1 mRNA CTD PMID:28801915 NCBI chr 7:132,239,200...132,256,592
Ensembl chr 7:132,239,729...132,256,591 		JBrowse link
G Adam19 ADAM metallopeptidase domain 19 increases expression EXP manganese chloride results in increased expression of ADAM19 mRNA CTD PMID:28801915 NCBI chr10:30,491,362...30,583,115
Ensembl chr10:30,491,405...30,583,105 		JBrowse link
G Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 decreases expression EXP manganese chloride results in decreased expression of ADAMTS1 mRNA CTD PMID:28801915 NCBI chr11:24,932,227...24,941,068
Ensembl chr11:24,931,761...24,941,103 		JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 decreases expression EXP manganese chloride results in decreased expression of ADAMTS5 mRNA CTD PMID:28801915 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205 		JBrowse link
G Adcy6 adenylate cyclase 6 increases expression EXP manganese chloride results in increased expression of ADCY6 mRNA CTD PMID:28801915 NCBI chr 7:129,742,827...129,763,922
Ensembl chr 7:129,742,838...129,763,754 		JBrowse link
G Add2 adducin 2 increases expression EXP manganese chloride results in increased expression of ADD2 mRNA CTD PMID:28801915 NCBI chr 4:118,444,594...118,538,505
Ensembl chr 4:118,497,416...118,538,505 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing increases expression EXP manganese chloride results in increased expression of ADIPOQ mRNA CTD PMID:28801915 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin increases expression
decreases expression		 ISO
EXP		 manganese chloride results in increased expression of ADM mRNA
manganese chloride results in decreased expression of ADM mRNA		 CTD PMID:17175027 PMID:28801915 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Adora2a adenosine A2a receptor increases expression EXP manganese chloride results in increased expression of ADORA2A mRNA CTD PMID:28801915 NCBI chr20:13,315,848...13,333,386
Ensembl chr20:13,315,853...13,333,386 		JBrowse link
G Aen apoptosis enhancing nuclease increases expression EXP manganese chloride results in increased expression of AEN mRNA CTD PMID:28801915 NCBI chr 1:132,815,094...132,824,522
Ensembl chr 1:132,815,142...132,824,523 		JBrowse link
G Aff1 ALF transcription elongation factor 1 increases expression EXP manganese chloride results in increased expression of AFF1 mRNA CTD PMID:28801915 NCBI chr14:5,861,188...6,024,196
Ensembl chr14:5,863,961...6,024,729 		JBrowse link
G Afmid arylformamidase increases expression EXP manganese chloride results in increased expression of AFMID mRNA CTD PMID:28801915 NCBI chr10:103,046,129...103,061,718
Ensembl chr10:103,046,180...103,061,718 		JBrowse link
G Afp alpha-fetoprotein decreases expression EXP manganese chloride results in decreased expression of AFP mRNA CTD PMID:26745496 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480 		JBrowse link
G Ahnak2 AHNAK nucleoprotein 2 increases expression EXP manganese chloride results in increased expression of AHNAK2 mRNA CTD PMID:28801915 NCBI chr 6:131,830,668...131,876,311 JBrowse link
G Aicda activation-induced cytidine deaminase increases expression EXP manganese chloride results in increased expression of AICDA mRNA CTD PMID:28801915 NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972 		JBrowse link
G Aif1 allograft inflammatory factor 1 increases expression ISO manganese chloride results in increased expression of AIF1 protein CTD PMID:28595911 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Akap7 A-kinase anchoring protein 7 decreases expression ISO manganese chloride results in decreased expression of AKAP7 mRNA CTD PMID:17175027 NCBI chr 1:20,087,190...20,217,799
Ensembl chr 1:20,087,373...20,217,797 		JBrowse link
G Akr1b1 aldo-keto reductase family 1 member B1 increases expression EXP manganese chloride results in increased expression of AKR1B1 mRNA CTD PMID:22281203 NCBI chr 4:62,932,033...62,946,126
Ensembl chr 4:62,932,031...62,946,157 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation
multiple interactions		 EXP
ISO		 manganese chloride results in decreased phosphorylation of AKT1 protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]
[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased phosphorylation of AKT1 protein]		 CTD PMID:30040983 PMID:31676349 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin multiple interactions EXP [sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate co-treated with Mercuric Chloride co-treated with chromium trioxide co-treated with nickel chloride co-treated with manganese chloride co-treated with ferric chloride] results in decreased expression of ALB protein CTD PMID:17657459 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh18a1 aldehyde dehydrogenase 18 family, member A1 increases expression EXP manganese chloride results in increased expression of ALDH18A1 mRNA CTD PMID:28801915 NCBI chr 1:239,375,657...239,407,967
Ensembl chr 1:239,375,669...239,407,890 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP manganese chloride results in decreased expression of ALDH1A1 mRNA CTD PMID:28801915 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 increases expression EXP manganese chloride results in increased expression of ALDH4A1 mRNA CTD PMID:28801915 NCBI chr 5:151,880,002...151,905,491
Ensembl chr 5:151,830,701...151,925,345 		JBrowse link
G Aldoa aldolase, fructose-bisphosphate A increases expression EXP manganese chloride results in increased expression of ALDOA mRNA CTD PMID:22281203 NCBI chr 1:181,402,275...181,407,476
Ensembl chr 1:181,402,275...181,406,182 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C decreases expression EXP manganese chloride results in decreased expression of ALDOC mRNA CTD PMID:28801915 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Alkal1 ALK and LTK ligand 1 increases expression EXP manganese chloride results in increased expression of ALKAL1 mRNA CTD PMID:28801915 NCBI chr 5:13,019,729...13,049,913
Ensembl chr 5:13,019,429...13,049,948 		JBrowse link
G Amigo3 adhesion molecule with Ig like domain 3 increases expression EXP manganese chloride results in increased expression of AMIGO3 mRNA CTD PMID:28801915 NCBI chr 8:108,741,899...108,743,425
Ensembl chr 8:108,693,060...108,744,555 		JBrowse link
G Angpt2 angiopoietin 2 decreases expression EXP manganese chloride results in decreased expression of ANGPT2 mRNA CTD PMID:26745496 NCBI chr16:71,088,364...71,138,805
Ensembl chr16:71,088,364...71,138,804 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO manganese chloride results in increased expression of ANGPTL4 mRNA CTD PMID:17175027 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ankrd28 ankyrin repeat domain 28 increases expression EXP manganese chloride results in increased expression of ANKRD28 mRNA CTD PMID:28801915 NCBI chr16:6,918,487...7,050,244
Ensembl chr16:6,914,336...7,050,249 		JBrowse link
G Ano3 anoctamin 3 increases expression EXP manganese chloride results in increased expression of ANO3 mRNA CTD PMID:28801915 NCBI chr 3:97,235,671...97,550,090
Ensembl chr 3:97,238,354...97,550,154 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of ANP32A mRNA CTD PMID:35690225 Ensembl chr 8:62,827,456...62,865,443 JBrowse link
G Anxa3 annexin A3 decreases expression EXP manganese chloride results in decreased expression of ANXA3 mRNA CTD PMID:28801915 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Aopep aminopeptidase O decreases expression EXP manganese chloride results in decreased expression of AOPEP mRNA CTD PMID:28801915 NCBI chr17:1,811,922...2,127,316
Ensembl chr17:1,811,980...2,127,331 		JBrowse link
G Ap3b2 adaptor related protein complex 3 subunit beta 2 increases expression ISO manganese chloride results in increased expression of AP3B2 mRNA CTD PMID:17175027 NCBI chr 1:135,412,580...135,445,191
Ensembl chr 1:135,412,580...135,445,191 		JBrowse link
G Apbb3 amyloid beta precursor protein binding family B member 3 increases expression EXP manganese chloride results in increased expression of APBB3 mRNA CTD PMID:28801915 NCBI chr18:28,273,168...28,280,347
Ensembl chr18:28,270,545...28,280,094 		JBrowse link
G Apc APC regulator of WNT signaling pathway decreases expression
increases methylation		 ISO manganese chloride results in decreased expression of APC mRNA
manganese chloride results in increased methylation of APC gene		 CTD PMID:27913844 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696 		JBrowse link
G Apoa2 apolipoprotein A2 decreases expression EXP manganese chloride results in decreased expression of APOA2 mRNA CTD PMID:28801915 NCBI chr13:83,644,460...83,646,358
Ensembl chr13:83,644,470...83,646,355 		JBrowse link
G Apol2 apolipoprotein L, 2 increases expression ISO manganese chloride results in increased expression of APOL2 mRNA CTD PMID:17175027 NCBI chr 7:109,331,367...109,338,632
Ensembl chr 7:109,331,392...109,338,558 		JBrowse link
G Apold1 apolipoprotein L domain containing 1 increases expression EXP manganese chloride results in increased expression of APOLD1 mRNA CTD PMID:28801915 NCBI chr 4:167,768,437...167,825,706
Ensembl chr 4:167,818,271...167,825,706 		JBrowse link
G Aqp3 aquaporin 3 (Gill blood group) decreases expression EXP manganese chloride results in decreased expression of AQP3 mRNA CTD PMID:28801915 NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720 		JBrowse link
G Areg amphiregulin increases expression EXP manganese chloride results in increased expression of AREG mRNA CTD PMID:28801915 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arg1 arginase 1 increases expression
increases methylation
multiple interactions		 EXP
ISO		 manganese chloride results in increased expression of ARG1 mRNA
manganese chloride results in increased methylation of ARG1 gene
[manganese chloride results in increased abundance of Manganese] which results in increased expression of ARG1 mRNA		 CTD PMID:28801915 PMID:34018660 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 decreases expression EXP manganese chloride results in decreased expression of ARHGAP24 mRNA CTD PMID:28801915 NCBI chr14:6,800,631...7,184,001
Ensembl chr14:6,800,631...7,183,823 		JBrowse link
G Arhgdia Rho GDP dissociation inhibitor alpha decreases expression ISO manganese chloride results in decreased expression of ARHGDIA mRNA CTD PMID:17175027 NCBI chr10:105,854,526...105,858,020
Ensembl chr10:105,854,533...105,858,023 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 increases expression EXP manganese chloride results in increased expression of ARHGEF10 mRNA CTD PMID:28801915 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173 		JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 increases expression EXP manganese chloride results in increased expression of ARHGEF16 mRNA CTD PMID:28801915 NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212 		JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 increases expression
increases methylation		 ISO
EXP		 manganese chloride results in increased expression of ARHGEF4 mRNA
manganese chloride results in increased methylation of ARHGEF4 gene		 CTD PMID:17175027 PMID:28801915 NCBI chr 9:36,861,800...37,005,079
Ensembl chr 9:36,861,835...37,005,075 		JBrowse link
G Arhgef6 Rac/Cdc42 guanine nucleotide exchange factor 6 increases expression EXP manganese chloride results in increased expression of ARHGEF6 mRNA CTD PMID:28801915 NCBI chr  X:135,145,447...135,264,636
Ensembl chr  X:135,146,786...135,275,304 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 decreases expression EXP manganese chloride results in decreased expression of ARHGEF7 mRNA CTD PMID:28801915 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Arid3a AT-rich interaction domain 3A increases expression EXP manganese chloride results in increased expression of ARID3A mRNA CTD PMID:28801915 NCBI chr 7:9,755,291...9,781,260
Ensembl chr 7:9,755,294...9,780,599 		JBrowse link
G Arl4c ADP ribosylation factor like GTPase 4C increases methylation
increases expression		 EXP manganese chloride results in increased methylation of ARL4C gene
manganese chloride results in increased expression of ARL4C mRNA		 CTD PMID:28801915 NCBI chr 9:89,300,335...89,303,770
Ensembl chr 9:89,298,005...89,304,513 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT gene mutant form inhibits the reaction [manganese chloride results in increased secretion of VEGFA protein] CTD PMID:19263519 NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580 		JBrowse link
G Asb5 ankyrin repeat and SOCS box-containing 5 decreases expression EXP manganese chloride results in decreased expression of ASB5 mRNA CTD PMID:28801915 NCBI chr16:37,237,869...37,305,207
Ensembl chr16:37,235,405...37,278,109 		JBrowse link
G Asns asparagine synthetase (glutamine-hydrolyzing) increases expression EXP manganese chloride results in increased expression of ASNS mRNA CTD PMID:28801915 NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423 		JBrowse link
G Ass1 argininosuccinate synthase 1 increases expression EXP manganese chloride results in increased expression of ASS1 mRNA CTD PMID:28801915 NCBI chr 3:14,747,355...14,796,909
Ensembl chr 3:14,747,368...14,796,903 		JBrowse link
G Aste1 asteroid homolog 1 increases expression EXP manganese chloride results in increased expression of ASTE1 mRNA CTD PMID:28801915 NCBI chr 8:106,026,570...106,044,694
Ensembl chr 8:106,026,515...106,044,430 		JBrowse link
G Atf1 activating transcription factor 1 increases phosphorylation
multiple interactions		 EXP manganese chloride results in increased phosphorylation of ATF1 protein
SB 203580 inhibits the reaction [manganese chloride results in increased phosphorylation of ATF1 protein]		 CTD PMID:16787641 NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670 		JBrowse link
G Atf2 activating transcription factor 2 increases activity
increases phosphorylation		 ISO manganese chloride results in increased activity of ATF2 protein
manganese chloride results in increased phosphorylation of ATF2 protein		 CTD PMID:19084589 PMID:20152896 NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression		 EXP manganese chloride promotes the reaction [EIF2AK3 protein results in increased expression of ATF4 mRNA]; SNCA protein promotes the reaction [manganese chloride results in increased expression of ATF4 mRNA]
manganese chloride results in increased expression of ATF4 mRNA; manganese chloride results in increased expression of ATF4 protein		 CTD PMID:23934647 PMID:23948121 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atf6 activating transcription factor 6 decreases expression
increases expression		 ISO
EXP		 manganese chloride results in decreased expression of ATF6 mRNA
manganese chloride results in increased expression of ATF6 protein		 CTD PMID:17175027 PMID:25732873 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atm ATM serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of ATM mRNA CTD PMID:17175027 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atoh8 atonal bHLH transcription factor 8 decreases expression EXP manganese chloride results in decreased expression of ATOH8 mRNA CTD PMID:26745496 PMID:28801915 NCBI chr 4:104,259,992...104,292,168
Ensembl chr 4:104,259,992...104,292,168 		JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 increases methylation EXP manganese chloride results in increased methylation of ATP2A3 gene CTD PMID:28801915 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748 		JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 increases methylation
decreases expression		 ISO manganese chloride results in increased methylation of ATP2B2 gene
manganese chloride results in decreased expression of ATP2B2 mRNA		 CTD PMID:27913844 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665 		JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 increases expression EXP manganese chloride results in increased expression of ATP2B4 mRNA CTD PMID:28801915 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Atp5f1c ATP synthase F1 subunit gamma decreases expression EXP manganese chloride results in decreased expression of ATP5C1 mRNA CTD PMID:22281203 NCBI chr17:68,423,927...68,446,169
Ensembl chr17:68,423,909...68,608,367 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A increases expression EXP manganese chloride results in increased expression of ATP6V1A mRNA CTD PMID:28801915 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Atp6v1e2 ATPase H+ transporting V1 subunit E2 decreases expression EXP
ISO		 manganese chloride results in decreased expression of ATP6V1E2 mRNA CTD PMID:28801915 NCBI chr 6:7,667,359...7,673,711
Ensembl chr 6:7,667,564...7,672,626 		JBrowse link
G Atp7a ATPase copper transporting alpha decreases expression
affects localization		 EXP manganese chloride results in decreased expression of ATP7A mRNA; manganese chloride results in decreased expression of ATP7A protein
manganese chloride affects the localization of ATP7A protein		 CTD PMID:24614235 NCBI chr  X:71,094,144...71,201,550
Ensembl chr  X:71,094,202...71,198,354 		JBrowse link
G Atp7b ATPase copper transporting beta affects localization
decreases expression		 EXP manganese chloride affects the localization of ATP7B protein
manganese chloride results in decreased expression of ATP7B mRNA; manganese chloride results in decreased expression of ATP7B protein		 CTD PMID:24614235 NCBI chr16:69,952,286...70,024,404
Ensembl chr16:69,951,778...70,023,636 		JBrowse link
G Atp8a1 ATPase phospholipid transporting 8A1 decreases expression ISO manganese chloride results in decreased expression of ATP8A1 mRNA CTD PMID:17175027 NCBI chr14:40,315,013...40,557,572
Ensembl chr14:40,315,049...40,554,611 		JBrowse link
G Avil advillin decreases expression
increases methylation		 EXP manganese chloride results in decreased expression of AVIL mRNA
manganese chloride results in increased methylation of AVIL gene		 CTD PMID:28801915 NCBI chr 7:62,825,459...62,844,103
Ensembl chr 7:62,826,025...62,844,071 		JBrowse link
G Axin2 axin 2 increases expression EXP manganese chloride results in increased expression of AXIN2 mRNA CTD PMID:28801915 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression EXP manganese chloride results in increased expression of BACH1 mRNA CTD PMID:28801915 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions		 EXP
ISO		 manganese chloride results in increased expression of BAX mRNA; manganese chloride results in increased expression of BAX protein
[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BAX protein; benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; Estradiol inhibits the reaction [manganese chloride results in increased expression of BAX protein]; Tamoxifen inhibits the reaction [manganese chloride results in increased expression of BAX protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of BAX protein]; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]; manganese chloride results in increased expression of and affects the localization of BAX protein
NTF3 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BAX protein]		 CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:29183790 More... NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression
multiple interactions
increases nitrosation
increases expression		 EXP
ISO		 manganese chloride results in decreased expression of BCL2 mRNA; manganese chloride results in decreased expression of BCL2 protein
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; [Plant Extracts co-treated with manganese chloride] affects the expression of BCL2 protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of BCL2 protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased expression of BCL2 protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BCL2 protein]; manganese chloride results in decreased expression of and affects the localization of BCL2 protein
manganese chloride results in increased nitrosation of BCL2 protein
corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased expression of and results in decreased phosphorylation of BCL2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride results in increased nitrosation of BCL2 protein]
manganese chloride results in increased expression of BCL2 mRNA
manganese chloride results in increased expression of BCL2 protein		 CTD PMID:17623882 PMID:21704098 PMID:25732873 PMID:26064043 PMID:28801915 More... NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP manganese chloride results in decreased expression of BCL2L1 protein CTD PMID:27107493 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l11 Bcl2-like 11 increases expression
decreases expression		 EXP manganese chloride results in increased expression of BCL2L11 protein
manganese chloride results in decreased expression of BCL2L11 mRNA		 CTD PMID:25732873 PMID:28801915 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcl6b BCL6B, transcription repressor increases expression EXP manganese chloride results in increased expression of BCL6B mRNA CTD PMID:28801915 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974 		JBrowse link
G Bdkrb2 bradykinin receptor B2 increases expression EXP manganese chloride results in increased expression of BDKRB2 mRNA CTD PMID:28801915 NCBI chr 6:124,472,317...124,502,497
Ensembl chr 6:124,472,566...124,502,497 		JBrowse link
G Bdnf brain-derived neurotrophic factor decreases expression
increases expression
increases methylation
multiple interactions		 ISO
EXP		 manganese chloride results in decreased expression of BDNF mRNA
manganese chloride results in increased expression of BDNF mRNA
manganese chloride results in increased methylation of BDNF gene
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of BDNF protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA; CREB1 protein affects the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of BDNF mRNA]		 CTD PMID:25698507 PMID:28801915 PMID:30951808 PMID:32659473 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 increases expression
multiple interactions
decreases expression
affects expression		 EXP
ISO		 manganese chloride results in increased expression of BECN1 protein
wortmannin inhibits the reaction [manganese chloride results in increased expression of BECN1 protein]
manganese chloride results in decreased expression of BECN1 protein
corynoxine B affects the reaction [manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]]; corynoxine B inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]; manganese chloride affects the reaction [HMGB1 protein binds to BECN1 protein]; manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [manganese chloride promotes the reaction [BCL2 protein binds to BECN1 protein]]
manganese chloride affects the expression of BECN1 protein		 CTD PMID:23604964 PMID:28856835 PMID:30578841 PMID:30672645 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bhlhe40 basic helix-loop-helix family, member e40 increases expression EXP manganese chloride results in increased expression of BHLHE40 mRNA CTD PMID:28801915 NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774 		JBrowse link
G Bid BH3 interacting domain death agonist increases cleavage
increases expression
multiple interactions		 EXP manganese chloride results in increased cleavage of BID protein
manganese chloride results in increased expression of BID protein; manganese chloride results in increased expression of BID protein modified form
bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased expression of BID protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased expression of BID protein]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein modified form]; pepstatin inhibits the reaction [manganese chloride results in increased expression of BID protein]		 CTD PMID:21704098 PMID:28378122 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 multiple interactions
decreases expression		 EXP Lithium Chloride inhibits the reaction [manganese chloride results in decreased expression of BIRC5 mRNA] CTD PMID:24464479 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Birc7 baculoviral IAP repeat-containing 7 increases expression EXP manganese chloride results in increased expression of BIRC7 mRNA CTD PMID:28801915 NCBI chr 3:168,047,824...168,052,606
Ensembl chr 3:168,047,824...168,052,606 		JBrowse link
G Bloc1s3 biogenesis of lysosomal organelles complex-1, subunit 3 increases expression EXP manganese chloride results in increased expression of BLOC1S3 mRNA CTD PMID:28801915 NCBI chr 1:79,155,914...79,158,326
Ensembl chr 1:79,155,693...79,158,505 		JBrowse link
G Blvra biliverdin reductase A increases expression EXP manganese chloride results in increased expression of BLVRA mRNA CTD PMID:22281203 NCBI chr 3:114,340,778...114,366,048
Ensembl chr 3:114,340,838...114,366,033 		JBrowse link
G Bmal1 basic helix-loop-helix ARNT like 1 decreases expression EXP manganese chloride results in decreased expression of BMAL1 mRNA CTD PMID:28511934 NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231 		JBrowse link
G Bmf Bcl2 modifying factor decreases expression EXP manganese chloride results in decreased expression of BMF mRNA CTD PMID:28801915 NCBI chr 3:105,499,534...105,520,159
Ensembl chr 3:105,499,538...105,520,145 		JBrowse link
G Bmp4 bone morphogenetic protein 4 increases expression ISO manganese chloride results in increased expression of BMP4 mRNA CTD PMID:17467022 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions
affects response to substance		 ISO [N-(3-(aminomethyl)benzyl)acetamidine results in decreased activity of NOS2 protein] inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; BNIP3 protein affects the reaction [manganese chloride affects the localization of CYCS protein]; Cycloheximide inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Dactinomycin inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; Glutathione inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]; manganese chloride results in increased expression of and affects the localization of BNIP3 protein
BNIP3 protein affects the susceptibility to manganese chloride		 CTD PMID:19442826 NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G Bpifb6 BPI fold containing family B, member 6 increases expression EXP manganese chloride results in increased expression of BPIFB6 mRNA CTD PMID:28801915 NCBI chr 3:142,383,701...142,395,308
Ensembl chr 3:142,381,374...142,395,308 		JBrowse link
G Bsn bassoon (presynaptic cytomatrix protein) increases expression EXP manganese chloride results in increased expression of BSN mRNA CTD PMID:28801915 NCBI chr 8:108,784,849...108,875,819
Ensembl chr 8:108,788,542...108,875,819 		JBrowse link
G Btnl5 butyrophilin-like 5 decreases expression EXP manganese chloride results in decreased expression of BTNL5 mRNA CTD PMID:28801915 NCBI chr20:4,366,780...4,376,385
Ensembl chr20:4,365,793...4,376,385 		JBrowse link
G Btnl7 butyrophilin-like 7 decreases expression EXP manganese chloride results in decreased expression of BTNL7 mRNA CTD PMID:28801915 NCBI chr20:4,301,078...4,313,522
Ensembl chr20:4,301,854...4,313,274 		JBrowse link
G Bub1 BUB1 mitotic checkpoint serine/threonine kinase decreases expression ISO manganese chloride results in decreased expression of BUB1 mRNA CTD PMID:17175027 NCBI chr 3:115,020,254...115,051,650
Ensembl chr 3:115,020,254...115,051,650 		JBrowse link
G C1qtnf4 C1q and TNF related 4 increases expression EXP manganese chloride results in increased expression of C1QTNF4 mRNA CTD PMID:28801915 NCBI chr 3:76,854,368...76,872,991
Ensembl chr 3:76,857,735...76,874,139 		JBrowse link
G C2cd4b C2 calcium-dependent domain containing 4B increases expression EXP manganese chloride results in increased expression of C2CD4B mRNA CTD PMID:28801915 NCBI chr 8:68,372,793...68,396,477
Ensembl chr 8:68,384,847...68,396,328 		JBrowse link
G C4bpa complement component 4 binding protein, alpha decreases expression EXP manganese chloride results in decreased expression of C4BPA mRNA CTD PMID:28801915 NCBI chr13:42,075,715...42,111,205
Ensembl chr13:42,075,717...42,111,205 		JBrowse link
G C5 complement C5 decreases expression EXP manganese chloride results in decreased expression of C5 mRNA CTD PMID:28801915 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G Cables1 Cdk5 and Abl enzyme substrate 1 decreases expression EXP manganese chloride results in decreased expression of CABLES1 mRNA CTD PMID:28801915 NCBI chr18:3,076,556...3,181,183
Ensembl chr18:3,075,524...3,181,181 		JBrowse link
G Calcoco2 calcium binding and coiled-coil domain 2 increases expression ISO manganese chloride results in increased expression of CALCOCO2 mRNA CTD PMID:17175027 NCBI chr10:81,055,467...81,069,298 JBrowse link
G Cald1 caldesmon 1 increases expression EXP manganese chloride results in increased expression of CALD1 mRNA CTD PMID:28801915 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Caly calcyon neuron-specific vesicular protein increases expression EXP manganese chloride results in increased expression of CALY mRNA CTD PMID:28801915 NCBI chr 1:194,862,671...194,873,861
Ensembl chr 1:194,862,672...194,873,551 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 increases expression ISO manganese chloride results in increased expression of CAMKK2 mRNA CTD PMID:15295902 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Camkv CaM kinase-like vesicle-associated decreases expression EXP manganese chloride results in decreased expression of CAMKV mRNA CTD PMID:28801915 NCBI chr 8:108,626,821...108,641,169
Ensembl chr 8:108,626,821...108,641,169 		JBrowse link
G Camp cathelicidin antimicrobial peptide increases expression EXP manganese chloride results in increased expression of CAMP mRNA CTD PMID:28801915 NCBI chr 8:109,841,729...109,843,543
Ensembl chr 8:109,841,729...109,843,543 		JBrowse link
G Camta2 calmodulin binding transcription activator 2 increases expression EXP manganese chloride results in increased expression of CAMTA2 mRNA CTD PMID:28801915 NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558 		JBrowse link
G Capn5 calpain 5 increases expression EXP manganese chloride results in increased expression of CAPN5 mRNA CTD PMID:28801915 NCBI chr 1:152,416,252...152,472,923
Ensembl chr 1:152,416,252...152,472,923 		JBrowse link
G Car5b carbonic anhydrase 5B decreases expression EXP manganese chloride results in decreased expression of CAR5B mRNA CTD PMID:28801915 NCBI chr  X:30,474,697...30,534,797
Ensembl chr  X:30,474,784...30,533,837 		JBrowse link
G Car8 carbonic anhydrase 8 increases expression EXP manganese chloride results in increased expression of CAR8 mRNA CTD PMID:26745496 NCBI chr 5:21,302,940...21,402,395
Ensembl chr 5:21,305,383...21,402,374 		JBrowse link
G Card14 caspase recruitment domain family, member 14 increases methylation ISO manganese chloride results in increased methylation of CARD14 gene CTD PMID:27913844 NCBI chr10:104,572,059...104,601,606
Ensembl chr10:104,566,424...104,601,905 		JBrowse link
G Card9 caspase recruitment domain family, member 9 decreases expression EXP manganese chloride results in decreased expression of CARD9 mRNA CTD PMID:28801915 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Casp12 caspase 12 multiple interactions
increases expression
increases cleavage		 ISO
EXP		 Deferoxamine promotes the reaction [manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein]; manganese chloride results in increased cleavage of and results in increased activity of CASP12 protein
manganese chloride results in increased expression of CASP12 mRNA; manganese chloride results in increased expression of CASP12 protein
SNCA protein promotes the reaction [manganese chloride results in increased expression of CASP12 protein]
manganese chloride results in increased cleavage of CASP12 protein
Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP12 protein]		 CTD PMID:23764342 PMID:23934647 PMID:23948121 PMID:25732873 PMID:26064043 More... NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp2 caspase 2 increases expression EXP manganese chloride results in increased expression of CASP2 mRNA CTD PMID:28801915 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379 		JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
increases expression
increases activity
increases methylation		 ISO
EXP		 manganese chloride results in increased cleavage of CASP3 protein
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in increased expression of CASP3 protein]; [manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; [manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of CASP3 protein modified form]; bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of CASP3 protein]; GW 506033X inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; Lithium Chloride inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; pyrazolanthrone inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]; Quercetin inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]; rhodioloside inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 mRNA]; U 0126 inhibits the reaction [manganese chloride results in increased expression of CASP3 protein]
manganese chloride results in increased expression of CASP3 mRNA; manganese chloride results in increased expression of CASP3 protein; manganese chloride results in increased expression of CASP3 protein modified form
[manganese chloride results in increased abundance of Manganese] which results in increased cleavage of CASP3 protein; Plant Extracts inhibits the reaction [manganese chloride results in increased cleavage of CASP3 protein]; PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
Deferoxamine promotes the reaction [manganese chloride results in increased activity of CASP3 protein]; SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP3 protein]
manganese chloride results in increased methylation of CASP3 gene		 CTD PMID:16787641 PMID:17483122 PMID:18178165 PMID:19815061 PMID:23764342 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp4 caspase 4 increases expression EXP manganese chloride results in increased expression of CASP4 mRNA CTD PMID:28801915 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 increases cleavage
multiple interactions		 EXP manganese chloride results in increased cleavage of CASP8 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP8 protein]		 CTD PMID:21704098 PMID:28378122 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases activity
multiple interactions
increases cleavage		 ISO
EXP		 manganese chloride results in increased activity of CASP9 protein
PRNP protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
SNCA protein inhibits the reaction [manganese chloride results in increased activity of CASP9 protein]
manganese chloride results in increased cleavage of CASP9 protein
bafilomycin A1 inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; CA 074 methyl ester inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]; pepstatin inhibits the reaction [manganese chloride results in increased cleavage of CASP9 protein]		 CTD PMID:16787641 PMID:17483122 PMID:21704098 PMID:25416158 PMID:28378122 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cat catalase decreases activity
multiple interactions
decreases expression		 EXP
ISO		 manganese chloride results in decreased activity of CAT protein
[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; [Plant Extracts co-treated with manganese chloride] results in increased expression of CAT protein; Estradiol inhibits the reaction [manganese chloride results in decreased expression of CAT protein]; Tamoxifen inhibits the reaction [manganese chloride results in decreased expression of CAT protein]
[manganese chloride results in increased abundance of Manganese] promotes the reaction [Ethanol results in decreased activity of CAT protein]; [manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein; Ethanol promotes the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased activity of CAT protein]; Quercetin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]; Silymarin inhibits the reaction [manganese chloride results in decreased activity of CAT protein]		 CTD PMID:20503066 PMID:22033861 PMID:22192907 PMID:26064043 PMID:28040552 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Catip ciliogenesis associated TTC17 interacting protein increases expression EXP manganese chloride results in increased expression of CATIP mRNA CTD PMID:28801915 NCBI chr 9:75,945,933...75,953,618
Ensembl chr 9:75,945,961...75,953,607 		JBrowse link
G Catsperd cation channel sperm associated auxiliary subunit delta increases expression EXP manganese chloride results in increased expression of CATSPERD mRNA CTD PMID:28801915 NCBI chr 9:1,459,967...1,498,342
Ensembl chr 9:1,460,001...1,498,344 		JBrowse link
G Cav2 caveolin 2 decreases expression EXP manganese chloride results in decreased expression of CAV2 mRNA CTD PMID:28801915 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Cbarp CACN subunit beta associated regulatory protein increases expression EXP manganese chloride results in increased expression of DOS mRNA CTD PMID:28801915 NCBI chr 7:9,566,637...9,575,204
Ensembl chr 7:9,566,364...9,575,204 		JBrowse link
G Cbs cystathionine beta synthase decreases expression EXP manganese chloride results in decreased expression of CBS mRNA CTD PMID:28801915 NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764 		JBrowse link
G Ccdc15 coiled-coil domain containing 15 increases expression EXP manganese chloride results in increased expression of CCDC15 mRNA CTD PMID:28801915 NCBI chr 8:36,991,147...37,068,849
Ensembl chr 8:36,998,867...37,068,919 		JBrowse link
G Ccdc175 coiled-coil domain containing 175 increases expression EXP manganese chloride results in increased expression of CCDC175 mRNA CTD PMID:28801915 NCBI chr 6:90,661,948...90,745,015
Ensembl chr 6:90,662,269...90,744,963 		JBrowse link
G Ccdc96 coiled-coil domain containing 96 increases expression EXP manganese chloride results in increased expression of CCDC96 mRNA CTD PMID:28801915 NCBI chr14:74,276,568...74,279,072
Ensembl chr14:74,276,960...74,278,888 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression EXP manganese chloride results in increased expression of CCL17 mRNA CTD PMID:28801915 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 increases expression EXP manganese chloride results in increased expression of CCL19 mRNA CTD PMID:28801915 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions
decreases secretion		 ISO
EXP		 manganese chloride inhibits the reaction [CCL2 protein results in increased expression of ICAM1 protein]; manganese chloride inhibits the reaction [Glucose results in increased secretion of CCL2 protein]
manganese chloride results in decreased secretion of CCL2 protein		 CTD PMID:23329836 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression EXP manganese chloride results in increased expression of CCL5 mRNA CTD PMID:28801915 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO
EXP		 manganese chloride results in increased expression of CCL7 mRNA CTD PMID:17175027 PMID:28801915 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
increases methylation		 ISO
EXP		 manganese chloride results in increased expression of CCN2 mRNA
manganese chloride results in increased methylation of CCN2 gene		 CTD PMID:17467022 PMID:28801915 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccna1 cyclin A1 increases expression EXP manganese chloride results in increased expression of CCNA1 mRNA CTD PMID:26745496 NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157 		JBrowse link
G Ccnb1 cyclin B1 multiple interactions ISO [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB1 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB1 protein CTD PMID:34822792 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Ccnb2 cyclin B2 decreases expression
multiple interactions		 ISO manganese chloride results in decreased expression of CCNB2 mRNA
[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA; [manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 mRNA]; YTHDC2 protein inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of CCNB2 protein]		 CTD PMID:17175027 PMID:34822792 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccng1 cyclin G1 increases expression EXP manganese chloride results in increased expression of CCNG1 mRNA CTD PMID:28801915 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO [manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein; manganese chloride promotes the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of CD28 protein]; Tetradecanoylphorbol Acetate inhibits the reaction [[manganese chloride co-treated with LCK protein] results in increased phosphorylation of CD28 protein] CTD PMID:8662792 NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685 		JBrowse link
G Cd44 CD44 molecule (Indian blood group) increases expression EXP manganese chloride results in increased expression of CD44 mRNA CTD PMID:28801915 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd48 Cd48 molecule increases expression ISO manganese chloride results in increased expression of CD48 mRNA CTD PMID:17175027 NCBI chr13:84,184,884...84,209,144
Ensembl chr13:84,185,532...84,209,142 		JBrowse link
G Cd6 Cd6 molecule decreases expression EXP manganese chloride results in decreased expression of CD6 mRNA CTD PMID:28801915 NCBI chr 1:207,442,873...207,481,703
Ensembl chr 1:207,442,877...207,481,634 		JBrowse link
G Cd74 CD74 molecule increases expression EXP manganese chloride results in increased expression of CD74 mRNA CTD PMID:28801915 NCBI chr18:54,256,757...54,266,003
Ensembl chr18:54,256,778...54,266,003 		JBrowse link
G Cd86 CD86 molecule increases expression ISO manganese chloride results in increased expression of CD86 protein CTD PMID:15737199 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cd8b CD8 subunit beta increases expression ISO manganese chloride results in increased expression of CD8B mRNA; manganese chloride results in increased expression of CD8B1 mRNA CTD PMID:17175027 NCBI chr 4:103,312,596...103,328,523
Ensembl chr 4:103,312,578...103,328,553 		JBrowse link
G Cdc42ep3 CDC42 effector protein 3 increases expression EXP manganese chloride results in increased expression of CDC42EP3 mRNA CTD PMID:28801915 NCBI chr 6:15,710,894...15,731,366
Ensembl chr 6:15,708,730...15,732,721 		JBrowse link
G Cdhr4 cadherin-related family member 4 decreases expression EXP manganese chloride results in decreased expression of CDHR4 mRNA CTD PMID:28801915 NCBI chr 8:108,682,594...108,690,358
Ensembl chr 8:108,682,613...108,690,367 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
increases expression
affects localization		 EXP Cycloheximide inhibits the reaction [manganese chloride results in increased expression of CDKN1A protein]
manganese chloride results in increased expression of CDKN1A mRNA; manganese chloride results in increased expression of CDKN1A protein
manganese chloride affects the localization of CDKN1A protein		 CTD PMID:22542671 PMID:28801915 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression EXP manganese chloride results in decreased expression of CDKN1C mRNA CTD PMID:28801915 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2b cyclin-dependent kinase inhibitor 2B increases expression EXP manganese chloride results in increased expression of CDKN2B mRNA CTD PMID:28801915 NCBI chr 5:104,009,839...104,019,082
Ensembl chr 5:104,010,680...104,019,050 		JBrowse link
G Cdkn2c cyclin-dependent kinase inhibitor 2C decreases expression ISO manganese chloride results in decreased expression of CDKN2C mRNA CTD PMID:17175027 NCBI chr 5:124,411,123...124,416,278
Ensembl chr 5:124,411,124...124,416,278 		JBrowse link
G Cdkn3 cyclin-dependent kinase inhibitor 3 decreases expression ISO manganese chloride results in decreased expression of CDKN3 mRNA CTD PMID:17175027 NCBI chr15:20,022,522...20,033,948
Ensembl chr15:20,022,664...20,033,945 		JBrowse link
G Cdnf cerebral dopamine neurotrophic factor increases expression EXP manganese chloride results in increased expression of CDNF mRNA CTD PMID:28801915 NCBI chr17:74,714,564...74,728,639
Ensembl chr17:74,713,564...74,728,639 		JBrowse link
G Cdyl2 chromodomain Y-like 2 increases expression EXP manganese chloride results in increased expression of CDYL2 mRNA CTD PMID:28801915 NCBI chr19:44,591,734...44,783,258
Ensembl chr19:44,597,459...44,783,022 		JBrowse link
G Cebpd CCAAT/enhancer binding protein delta increases expression ISO manganese chloride results in increased expression of CEBPD mRNA CTD PMID:17175027 NCBI chr11:84,764,670...84,765,808
Ensembl chr11:84,764,565...84,765,829 		JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 increases expression ISO manganese chloride results in increased expression of CELSR1 mRNA CTD PMID:17175027 NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164 		JBrowse link
G Cep112 centrosomal protein 112 increases expression EXP manganese chloride results in increased expression of CEP112 mRNA CTD PMID:28801915 NCBI chr10:93,366,059...93,833,133
Ensembl chr10:93,366,136...93,833,131 		JBrowse link
G Cep128 centrosomal protein 128 decreases expression ISO manganese chloride results in decreased expression of CEP128 mRNA CTD PMID:17175027 NCBI chr 6:109,951,009...110,328,686
Ensembl chr 6:109,951,061...110,328,713 		JBrowse link
G Cers1 ceramide synthase 1 increases expression EXP manganese chloride results in increased expression of CERS1 mRNA CTD PMID:28801915 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,104,466...19,112,519 		JBrowse link
G Cers6 ceramide synthase 6 increases expression EXP manganese chloride results in increased expression of CERS6 mRNA CTD PMID:28801915 NCBI chr 3:53,630,636...53,879,692
Ensembl chr 3:53,630,959...53,876,848 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression EXP manganese chloride results in increased expression of CFLAR mRNA CTD PMID:28801915 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034