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Accession:CHEBI:3510 term browser browse the term
Definition:A third-generation cephalosporin antibiotic with a [(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino substituent at the 7 position of the cephem skeleton. An orally-administered agent, ceftibuten is used as the dihydrate to treat urinary-tract and respiratory-tract infections.
Synonyms:exact_synonym: 7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (+)-(6R,7R)-7-((Z)-2-(2-amino-4-thiazolyl)-4-carboxycrotonamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid;   (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-4-carboxybut-2-enoyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Formula=C15H14N4O6S2;   InChI=1S/C15H14N4O6S2/c16-15-17-7(5-27-15)6(1-2-9(20)21)11(22)18-10-12(23)19-8(14(24)25)3-4-26-13(10)19/h1,3,5,10,13H,2,4H2,(H2,16,17)(H,18,22)(H,20,21)(H,24,25)/b6-1-/t10-,13-/m1/s1;   InChIKey=UNJFKXSSGBWRBZ-BJCIPQKHSA-N;   SMILES=[H][C@]12SCC=C(N1C(=O)[C@H]2NC(=O)C(=C/CC(O)=O)\\c1csc(N)n1)C(O)=O;   ceftibutene;   ceftibuteno;   ceftibutenum;   cis-ceftibuten
 alt_id: CHEBI:554578
 xref: Beilstein:5892046 "Beilstein";   CAS:97519-39-6 "ChemIDplus";   CAS:97519-39-6 "KEGG COMPOUND";   DrugBank:DB01415;   Drug_Central:562 "DrugCentral";   KEGG:C08117;   KEGG:D00922
 xref_mesh: MESH:C054360
 xref: PMID:29017833 "Europe PMC";   PMID:9250548 "Europe PMC";   Patent:CN105153198;   Patent:CN106397455;   Patent:EP136721;   Patent:US4634697;   Wikipedia:Ceftibuten

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ceftibuten term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Slc15a1 solute carrier family 15 member 1 JBrowse link 15 106,800,081 106,844,668 RGD:6480464
G Slc22a6 solute carrier family 22 member 6 JBrowse link 1 224,824,809 224,833,284 RGD:6480464
G Slc22a8 solute carrier family 22 member 8 JBrowse link 1 224,799,444 224,818,482 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19679
    role 19623
      biological role 19621
        antimicrobial agent 17158
          antibacterial agent 12907
            antibacterial drug 3042
              ceftibuten 3
                ceftibuten dihydrate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19679
    subatomic particle 19675
      composite particle 19675
        hadron 19675
          baryon 19675
            nucleon 19675
              atomic nucleus 19675
                atom 19675
                  main group element atom 19555
                    p-block element atom 19555
                      carbon group element atom 19438
                        carbon atom 19430
                          organic molecular entity 19430
                            organic group 18351
                              organic divalent group 18340
                                organodiyl group 18340
                                  carbonyl group 18225
                                    carbonyl compound 18225
                                      carboxylic acid 17930
                                        carboacyl group 16948
                                          univalent carboacyl group 16948
                                            carbamoyl group 16627
                                              carboxamide 16627
                                                lactam 2856
                                                  beta-lactam 710
                                                    beta-lactam antibiotic 698
                                                      cephem 537
                                                        cephalosporin 536
                                                          ceftibuten 3
                                                            ceftibuten dihydrate 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.