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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:p-tert-Amylphenol
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Accession:CHEBI:35096 term browser browse the term
Definition:An alkylbenzene that has formula C11H16O.
Synonyms:related_synonym: 4-(1,1,3,3-Tetramethylbutyl)phenol;   4-(1,1,3,3-Tetramethylbutyl)phenol (ACD/Name 4.0);   4-(2-methylbutan-2-yl)phenol;   4-Tert-Octylphenol;   4-t-Amylphenol;   4-tert-Pentylphenol;   Formula=C11H16O;   InChI=1S/C11H16O/c1-4-11(2,3)9-5-7-10(12)8-6-9/h5-8,12H,4H2,1-3H3;   InChIKey=NRZWYNLTFLDQQX-UHFFFAOYSA-N;   Octylphenol pt;   Para-tert-Octylphenol;   SMILES=CCC(C)(C)c1ccc(O)cc1;   Tert-Octylphenol, flaked;   p-(1,1,3,3-Tetramethylbutyl)phenol;   p-(Tert-octyl)-Phenol;   p-Octylphenol;   p-Octylphenol (VAN);   p-Terc.oktylfenol;   p-Terc.oktylfenol(Czech);   p-tert-Octylphenol
 xref: CAS:140-66-9;   CAS:80-46-6;   HMDB:HMDB0013825;   KEGG:C14226
 xref_mesh: MESH:C019566


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p-tert-Amylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACACA acetyl-CoA carboxylase alpha decreases expression ISO 4-tert-octylphenol results in decreased expression of ACACA mRNA CTD PMID:26164745 NCBI chr17:37,084,992...37,406,836
Ensembl chr17:37,084,992...37,406,836
JBrowse link
G AFAP1L2 actin filament associated protein 1 like 2 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of AFAP1L2 mRNA CTD PMID:23626723 NCBI chr10:114,280,760...114,404,672
Ensembl chr10:114,294,824...114,404,756
JBrowse link
G AP1B1 adaptor related protein complex 1 subunit beta 1 increases expression ISO 4-tert-octylphenol results in increased expression of AP1B1 mRNA CTD PMID:17011747 NCBI chr22:29,327,680...29,388,570
Ensembl chr22:29,327,680...29,388,583
JBrowse link
G AR androgen receptor affects binding
decreases expression
decreases activity
multiple interactions
ISO
EXP
p-tert-amylphenol binds to AR protein
4-tert-octylphenol results in decreased expression of AR mRNA
4-tert-octylphenol results in decreased activity of AR protein
4-tert-octylphenol binds to AR protein
4-tert-octylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [Metribolone results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]; p-tert-amylphenol inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
4-tert-octylphenol results in decreased expression of AR protein
CTD PMID:10822019 PMID:12161000 PMID:14565775 PMID:18294747 PMID:18324785 PMID:21463676 PMID:26867867 PMID:29162470 PMID:33049310 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619
JBrowse link
G ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 increases expression ISO 4-tert-octylphenol results in increased expression of ARIH2 mRNA CTD PMID:17011747 NCBI chr 3:48,918,821...48,986,382
Ensembl chr 3:48,918,821...48,986,382
JBrowse link
G ATF4 activating transcription factor 4 decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of ATF4 mRNA
4-tert-octylphenol results in increased expression of ATF4 mRNA
CTD PMID:17011747 NCBI chr22:39,514,494...39,522,686
Ensembl chr22:39,519,695...39,522,683
JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 increases expression ISO 4-tert-octylphenol results in increased expression of ATP1B3 mRNA CTD PMID:17011747 NCBI chr 3:141,876,643...141,926,549
Ensembl chr 3:141,876,124...141,926,549
JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 increases expression ISO 4-tert-octylphenol results in increased expression of ATP2B1 mRNA CTD PMID:17011747 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,300
JBrowse link
G B2M beta-2-microglobulin increases expression ISO 4-tert-octylphenol results in increased expression of B2M mRNA CTD PMID:17011747 NCBI chr15:44,711,492...44,718,145
Ensembl chr15:44,711,487...44,718,851
JBrowse link
G B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of B3GNT3 mRNA CTD PMID:23626723 NCBI chr19:17,794,828...17,813,576
Ensembl chr19:17,794,828...17,813,576
JBrowse link
G BNIP3L BCL2 interacting protein 3 like decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of BNIP3L mRNA
4-tert-octylphenol results in increased expression of BNIP3L mRNA
CTD PMID:17011747 NCBI chr 8:26,383,054...26,413,127
Ensembl chr 8:26,383,054...26,505,636
JBrowse link
G C3 complement C3 increases expression ISO 4-tert-octylphenol results in increased expression of C3 mRNA; 4-tert-octylphenol results in increased expression of C3 protein CTD PMID:10822019 PMID:11086226 PMID:17011747 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562
JBrowse link
G CASP3 caspase 3 multiple interactions ISO 4-tert-octylphenol results in increased expression of and results in increased activity of CASP3 protein; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of and results in increased activity of CASP3 protein CTD PMID:29029336 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,649,509
JBrowse link
G CCBE1 collagen and calcium binding EGF domains 1 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of CCBE1 mRNA CTD PMID:23626723 NCBI chr18:59,430,939...59,698,181
Ensembl chr18:59,430,939...59,697,662
JBrowse link
G CCND1 cyclin D1 multiple interactions
increases expression
EXP ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]
4-tert-octylphenol results in increased expression of CCND1 mRNA; 4-tert-octylphenol results in increased expression of CCND1 protein
CTD PMID:24684733 NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
JBrowse link
G CDA cytidine deaminase increases expression ISO 4-tert-octylphenol results in increased expression of CDA mRNA; 4-tert-octylphenol results in increased expression of CDA protein CTD PMID:30487447 NCBI chr 1:20,589,097...20,618,903
Ensembl chr 1:20,589,086...20,618,903
JBrowse link
G CDH1 cadherin 1 multiple interactions
decreases expression
EXP Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased expression of CDH1 protein] CTD PMID:27145024 NCBI chr16:68,737,292...68,835,537
Ensembl chr16:68,737,292...68,835,537
JBrowse link
G CDH2 cadherin 2 decreases localization
decreases expression
increases expression
multiple interactions
ISO
EXP
4-tert-octylphenol results in decreased localization of CDH2 protein
4-tert-octylphenol results in decreased expression of CDH2 protein
4-tert-octylphenol results in increased expression of CDH2 protein
Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CDH2 protein]
CTD PMID:15082077 PMID:27145024 NCBI chr18:27,932,878...28,177,130
Ensembl chr18:27,932,879...28,177,946
JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A decreases expression EXP 4-tert-octylphenol results in decreased expression of CDKN1A mRNA CTD PMID:24684733 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
JBrowse link
G CEBPA CCAAT enhancer binding protein alpha decreases expression ISO 4-tert-octylphenol results in decreased expression of CEBPA mRNA CTD PMID:26164745 NCBI chr19:33,299,934...33,302,564
Ensembl chr19:33,299,934...33,302,534
JBrowse link
G CLDN5 claudin 5 increases expression ISO 4-tert-octylphenol results in increased expression of CLDN5 mRNA CTD PMID:17011747 NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545
JBrowse link
G CLU clusterin decreases expression ISO 4-tert-octylphenol results in decreased expression of CLU mRNA CTD PMID:10822019 PMID:14689164 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700
JBrowse link
G COL14A1 collagen type XIV alpha 1 chain multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of COL14A1 mRNA CTD PMID:23626723 NCBI chr 8:120,124,467...120,373,573
Ensembl chr 8:120,059,780...120,373,573
JBrowse link
G COL1A2 collagen type I alpha 2 chain increases expression ISO 4-tert-octylphenol results in increased expression of COL1A2 mRNA CTD PMID:17011747 NCBI chr 7:94,394,895...94,431,227
Ensembl chr 7:94,394,895...94,431,227
JBrowse link
G CRABP2 cellular retinoic acid binding protein 2 increases expression ISO 4-tert-octylphenol results in increased expression of CRABP2 mRNA CTD PMID:17011747 NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816
JBrowse link
G CREB1 cAMP responsive element binding protein 1 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased phosphorylation of CREB1 protein; Wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in increased phosphorylation of CREB1 protein] CTD PMID:23626723 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CSF1R colony stimulating factor 1 receptor multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of CSF1R mRNA CTD PMID:23626723 NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
JBrowse link
G CTSB cathepsin B multiple interactions
increases expression
EXP ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB protein]
4-tert-octylphenol results in increased expression of CTSB mRNA; 4-tert-octylphenol results in increased expression of CTSB protein
CTD PMID:23219593 NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
JBrowse link
G CTSD cathepsin D increases expression
multiple interactions
EXP 4-tert-octylphenol results in increased expression of CTSD mRNA; 4-tert-octylphenol results in increased expression of CTSD protein
ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSD mRNA]
CTD PMID:23219593 NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
JBrowse link
G CYCS cytochrome c, somatic increases expression ISO 4-tert-octylphenol results in increased expression of CYCS mRNA CTD PMID:17011747 NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 multiple interactions
decreases expression
ISO [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP11A1 mRNA
4-tert-octylphenol results in decreased expression of CYP11A1 mRNA; 4-tert-octylphenol results in decreased expression of CYP11A1 protein
CTD PMID:17696135 PMID:29029336 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 multiple interactions
decreases expression
ISO [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA
4-tert-octylphenol results in decreased expression of CYP17A1 mRNA
CTD PMID:17696135 PMID:29029336 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472
JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 decreases expression
multiple interactions
ISO 4-tert-octylphenol results in decreased expression of CYP19A1 mRNA
[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein
CTD PMID:29029336 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601
JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 increases response to substance EXP CYP1A1 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536
JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 increases response to substance EXP CYP2C19 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547
JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 increases response to substance EXP CYP2C9 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091
JBrowse link
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 increases expression ISO 4-tert-octylphenol results in increased expression of CYP4A22 mRNA CTD PMID:17011747 NCBI chr 1:47,137,441...47,149,738
Ensembl chr 1:47,137,435...47,149,735
JBrowse link
G DIO2 iodothyronine deiodinase 2 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DIO2 mRNA CTD PMID:23626723 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757
JBrowse link
G DNMT3A DNA methyltransferase 3 alpha multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3A mRNA; [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3A protein; Wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3A protein] CTD PMID:23626723 NCBI chr 2:25,227,874...25,342,590
Ensembl chr 2:25,227,855...25,342,590
JBrowse link
G DNMT3B DNA methyltransferase 3 beta multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B mRNA; [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B protein; Wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B protein] CTD PMID:23626723 NCBI chr20:32,762,385...32,809,356
Ensembl chr20:32,762,385...32,809,356
JBrowse link
G DNMT3L DNA methyltransferase 3 like multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3L mRNA; [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3L protein; Wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3L protein] CTD PMID:23626723 NCBI chr21:44,246,339...44,261,897
Ensembl chr21:44,246,339...44,262,216
JBrowse link
G DYNLL1 dynein light chain LC8-type 1 decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of DYNLL1 mRNA
4-tert-octylphenol results in increased expression of DYNLL1 mRNA
CTD PMID:17011747 NCBI chr12:120,469,842...120,498,493
Ensembl chr12:120,469,850...120,498,493
JBrowse link
G EBF2 EBF transcription factor 2 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of EBF2 mRNA CTD PMID:23626723 NCBI chr 8:25,841,725...26,045,413
Ensembl chr 8:25,841,725...26,045,413
JBrowse link
G EGF epidermal growth factor increases expression ISO 4-tert-octylphenol results in increased expression of EGF mRNA CTD PMID:17011747 NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766
JBrowse link
G EGFR epidermal growth factor receptor increases expression ISO 4-tert-octylphenol results in increased expression of EGFR mRNA CTD PMID:17011747 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628
JBrowse link
G ESR1 estrogen receptor 1 affects binding
decreases expression
increases activity
increases expression
multiple interactions
EXP
ISO
4-tert-octylphenol binds to ESR1 protein; p-tert-amylphenol binds to ESR1 protein
4-tert-octylphenol results in decreased expression of ESR1 mRNA; 4-tert-octylphenol results in decreased expression of ESR1 protein
4-tert-octylphenol results in increased activity of ESR1 protein
4-tert-octylphenol results in increased expression of ESR1 mRNA
4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased expression of ESR1 mRNA]
4-tert-octylphenol results in increased activity of ESR1 protein mutant form
4-tert-octylphenol binds to and results in increased activity of ESR1 protein; 4-tert-octylphenol inhibits the reaction [Estradiol binds to ESR1 protein]; 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA1 protein]; 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA2 protein]; ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]; ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB mRNA]; ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CTSD mRNA]; p-tert-amylphenol binds to and results in increased activity of ESR1 protein; p-tert-amylphenol promotes the reaction [ESR1 protein alternative form binds to ESR1 protein alternative form]
CTD PMID:10964929 PMID:11086226 PMID:11162928 PMID:11530281 PMID:11750080 PMID:12161000 PMID:12504345 PMID:12737316 PMID:17141713 PMID:19233257 PMID:19666091 PMID:19913605 PMID:23219593 PMID:23557686 PMID:24684733 PMID:25012808 PMID:27633901 PMID:29162470 PMID:30061528 PMID:33049310 NCBI chr 6:151,654,148...152,129,619
Ensembl chr 6:151,656,691...152,129,619
JBrowse link
G ESR2 estrogen receptor 2 affects binding
multiple interactions
increases expression
EXP 4-tert-octylphenol binds to ESR2 protein; p-tert-amylphenol binds to ESR2 protein
4-tert-octylphenol binds to and results in increased activity of ESR2 protein; 4-tert-octylphenol inhibits the reaction [Estradiol binds to ESR2 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA1 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA2 protein]; p-tert-amylphenol binds to and results in increased activity of ESR2 protein
4-tert-octylphenol results in increased expression of ESR2 mRNA
CTD PMID:10964929 PMID:12161000 PMID:12224631 PMID:12737316 PMID:19913605 PMID:27633901 PMID:33049310 NCBI chr14:64,226,707...64,338,631
Ensembl chr14:64,084,232...64,338,112
JBrowse link
G ESRRG estrogen related receptor gamma increases activity EXP 4-tert-octylphenol results in increased activity of ESRRG protein CTD PMID:31127318 NCBI chr 1:216,503,246...217,137,702
Ensembl chr 1:216,503,246...217,137,755
JBrowse link
G FAM153A family with sequence similarity 153 member A multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of FAM153A mRNA CTD PMID:23626723 NCBI chr 5:177,694,247...177,783,518
Ensembl chr 5:177,707,981...177,783,398
JBrowse link
G FASN fatty acid synthase decreases expression ISO 4-tert-octylphenol results in decreased expression of FASN mRNA; 4-tert-octylphenol results in decreased expression of FASN protein CTD PMID:26164745 NCBI chr17:82,078,338...82,098,303
Ensembl chr17:82,078,338...82,098,294
JBrowse link
G FCGR3A Fc fragment of IgG receptor IIIa multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of FCGR3A mRNA CTD PMID:23626723 NCBI chr 1:161,541,759...161,550,737
Ensembl chr 1:161,541,759...161,550,737
JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO 4-tert-octylphenol results in increased expression of FOS mRNA CTD PMID:17011747 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
JBrowse link
G FXYD4 FXYD domain containing ion transport regulator 4 increases expression ISO 4-tert-octylphenol results in increased expression of FXYD4 mRNA CTD PMID:17011747 NCBI chr10:43,371,636...43,376,335
Ensembl chr10:43,371,636...43,376,335
JBrowse link
G GAPDH glyceraldehyde-3-phosphate dehydrogenase increases expression ISO 4-tert-octylphenol results in increased expression of GAPDH mRNA CTD PMID:10822019 NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374
JBrowse link
G GCNT4 glucosaminyl (N-acetyl) transferase 4 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of GCNT4 mRNA CTD PMID:23626723 NCBI chr 5:75,025,346...75,052,558
Ensembl chr 5:75,025,346...75,052,558
JBrowse link
G GH1 growth hormone 1 increases expression
multiple interactions
ISO 4-tert-octylphenol results in increased expression of GH1 mRNA; 4-tert-octylphenol results in increased expression of GH1 protein
Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 protein]
CTD PMID:19145065 NCBI chr17:63,917,203...63,918,839
Ensembl chr17:63,917,200...63,918,839
JBrowse link
G GJA1 gap junction protein alpha 1 decreases expression ISO 4-tert-octylphenol results in decreased expression of GJA1 protein CTD PMID:15082077 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727
JBrowse link
G GMEB2 glucocorticoid modulatory element binding protein 2 decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of GMEB2 mRNA
4-tert-octylphenol results in increased expression of GMEB2 mRNA
CTD PMID:17011747 NCBI chr20:63,587,602...63,627,101
Ensembl chr20:63,587,602...63,627,101
JBrowse link
G GNL3 G protein nucleolar 3 increases expression ISO 4-tert-octylphenol results in increased expression of GNL3 mRNA CTD PMID:17011747 NCBI chr 3:52,685,920...52,694,497
Ensembl chr 3:52,681,156...52,694,497
JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 increases expression EXP 4-tert-octylphenol results in increased expression of GPER1 mRNA CTD PMID:29783106 NCBI chr 7:1,087,118...1,093,810
Ensembl chr 7:1,082,208...1,093,815
JBrowse link
G GTF2A2 general transcription factor IIA subunit 2 increases expression ISO 4-tert-octylphenol results in increased expression of GTF2A2 mRNA CTD PMID:17011747 NCBI chr15:59,638,062...59,657,515
Ensembl chr15:59,638,062...59,657,541
JBrowse link
G H2BC7 H2B clustered histone 7 decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of HIST1H2BQ mRNA
4-tert-octylphenol results in increased expression of HIST1H2BQ mRNA
CTD PMID:17011747 NCBI chr 6:26,199,516...26,199,988
Ensembl chr 6:26,199,520...26,200,715
JBrowse link
G H3-3B H3.3 histone B increases expression ISO 4-tert-octylphenol results in increased expression of H3F3B mRNA CTD PMID:17011747 NCBI chr17:75,776,434...75,779,779
Ensembl chr17:75,776,434...75,785,893
JBrowse link
G HAS2 hyaluronan synthase 2 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of HAS2 mRNA CTD PMID:23626723 NCBI chr 8:121,612,116...121,641,440
Ensembl chr 8:121,612,116...121,641,440
JBrowse link
G HNF1B HNF1 homeobox B increases expression ISO 4-tert-octylphenol results in increased expression of HNF1B mRNA CTD PMID:17011747 NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,059
JBrowse link
G HOXA10 homeobox A10 multiple interactions
decreases expression
ISO 4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of HOXA10 mRNA]; [Fulvestrant co-treated with 4-tert-octylphenol] results in decreased expression of HOXA10 mRNA
4-tert-octylphenol results in decreased expression of HOXA10 mRNA
CTD PMID:30061528 NCBI chr 7:27,170,605...27,179,861
Ensembl chr 7:27,170,592...27,180,261
JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase increases expression ISO 4-tert-octylphenol results in increased expression of HPGD mRNA CTD PMID:23664861 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154
JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of HSD11B1 mRNA
4-tert-octylphenol results in increased expression of HSD11B1 mRNA
CTD PMID:17011747 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949
JBrowse link
G HSD17B10 hydroxysteroid 17-beta dehydrogenase 10 increases expression ISO 4-tert-octylphenol results in increased expression of HSD17B10 mRNA CTD PMID:17011747 NCBI chr  X:53,431,258...53,434,376
Ensembl chr  X:53,431,258...53,434,370
JBrowse link
G HSD17B7 hydroxysteroid 17-beta dehydrogenase 7 increases expression ISO 4-tert-octylphenol results in increased expression of HSD17B7 mRNA CTD PMID:17011747 NCBI chr 1:162,790,702...162,812,823
Ensembl chr 1:162,790,702...162,812,823
JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO 4-tert-octylphenol results in decreased expression of HSD3B1 mRNA CTD PMID:29029336 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054
JBrowse link
G IGF1 insulin like growth factor 1 increases expression ISO 4-tert-octylphenol results in increased expression of IGF1 mRNA CTD PMID:17011747 NCBI chr12:102,395,860...102,481,839
Ensembl chr12:102,395,874...102,481,744
JBrowse link
G IRF1 interferon regulatory factor 1 increases expression ISO 4-tert-octylphenol results in increased expression of IRF1 mRNA CTD PMID:17011747 NCBI chr 5:132,481,609...132,490,789
Ensembl chr 5:132,440,440...132,508,719
JBrowse link
G ITGA6 integrin subunit alpha 6 increases expression ISO 4-tert-octylphenol results in increased expression of ITGA6 mRNA CTD PMID:17011747 NCBI chr 2:172,427,336...172,506,459
Ensembl chr 2:172,427,354...172,506,459
JBrowse link
G IYD iodotyrosine deiodinase multiple interactions EXP 4-tert-octylphenol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 6:150,368,854...150,405,969
Ensembl chr 6:150,368,892...150,405,969
JBrowse link
G KCNB2 potassium voltage-gated channel subfamily B member 2 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of KCNB2 mRNA CTD PMID:23626723 NCBI chr 8:72,537,225...72,945,890
Ensembl chr 8:72,537,225...72,938,349
JBrowse link
G KCNV1 potassium voltage-gated channel modifier subfamily V member 1 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of KCNV1 mRNA CTD PMID:23626723 NCBI chr 8:109,963,636...109,975,771
Ensembl chr 8:109,963,636...109,975,771
JBrowse link
G KLF9 Kruppel like factor 9 increases expression ISO 4-tert-octylphenol results in increased expression of KLF9 mRNA CTD PMID:17011747 NCBI chr 9:70,384,604...70,414,657
Ensembl chr 9:70,384,604...70,414,657
JBrowse link
G KLK6 kallikrein related peptidase 6 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of KLK6 mRNA CTD PMID:23626723 NCBI chr19:50,958,631...50,969,598
Ensembl chr19:50,958,631...50,969,673
JBrowse link
G LHB luteinizing hormone subunit beta decreases expression
affects expression
ISO 4-tert-octylphenol results in decreased expression of LHB protein
4-tert-octylphenol affects the expression of LHB protein
CTD PMID:15888928 PMID:17033158 NCBI chr19:49,015,980...49,017,091
Ensembl chr19:49,015,980...49,017,091
JBrowse link
G LHCGR luteinizing hormone/choriogonadotropin receptor increases expression ISO 4-tert-octylphenol results in increased expression of LHCGR mRNA CTD PMID:17011747 NCBI chr 2:48,686,774...48,755,724
Ensembl chr 2:48,686,774...48,755,730
JBrowse link
G LIF LIF interleukin 6 family cytokine decreases expression ISO 4-tert-octylphenol results in decreased expression of LIF mRNA CTD PMID:30061528 NCBI chr22:30,240,453...30,257,487
Ensembl chr22:30,240,453...30,246,759
JBrowse link
G LRATD2 LRAT domain containing 2 increases expression ISO 4-tert-octylphenol results in increased expression of LRATD2 mRNA CTD PMID:17011747 NCBI chr 8:126,552,443...126,558,498
Ensembl chr 8:126,552,443...126,558,478
JBrowse link
G LSP1 lymphocyte specific protein 1 increases expression ISO 4-tert-octylphenol results in increased expression of LSP1 mRNA CTD PMID:17011747 NCBI chr11:1,853,084...1,892,263
Ensembl chr11:1,850,904...1,892,267
JBrowse link
G MAP3K12 mitogen-activated protein kinase kinase kinase 12 increases expression ISO 4-tert-octylphenol results in increased expression of MAP3K12 mRNA CTD PMID:17011747 NCBI chr12:53,479,669...53,501,205
Ensembl chr12:53,479,669...53,500,063
JBrowse link
G MAPK1 mitogen-activated protein kinase 1 multiple interactions
decreases phosphorylation
EXP [Diethylhexyl Phthalate co-treated with 4-tert-octylphenol] results in decreased phosphorylation of MAPK1 protein; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK1 protein] CTD PMID:26133781 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
JBrowse link
G MAPK3 mitogen-activated protein kinase 3 multiple interactions
decreases phosphorylation
EXP [Diethylhexyl Phthalate co-treated with 4-tert-octylphenol] results in decreased phosphorylation of MAPK3 protein; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK3 protein] CTD PMID:26133781 NCBI chr16:30,114,105...30,123,309
Ensembl chr16:30,114,105...30,123,506
JBrowse link
G MECR mitochondrial trans-2-enoyl-CoA reductase increases expression ISO 4-tert-octylphenol results in increased expression of MECR mRNA CTD PMID:17011747 NCBI chr 1:29,192,657...29,230,948
Ensembl chr 1:29,192,657...29,230,942
JBrowse link
G MT3 metallothionein 3 increases expression ISO 4-tert-octylphenol results in increased expression of MT3 mRNA CTD PMID:17011747 NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
JBrowse link
G MUC1 mucin 1, cell surface associated increases expression
multiple interactions
ISO 4-tert-octylphenol results in increased expression of MUC1 mRNA; 4-tert-octylphenol results in increased expression of MUC1 protein
Fulvestrant promotes the reaction [4-tert-octylphenol results in increased expression of MUC1 mRNA]
CTD PMID:30061528 NCBI chr 1:155,185,824...155,192,915
Ensembl chr 1:155,185,824...155,192,916
JBrowse link
G NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of NAALAD2 mRNA CTD PMID:23626723 NCBI chr11:90,131,693...90,193,577
Ensembl chr11:90,131,515...90,192,894
JBrowse link
G NCOA1 nuclear receptor coactivator 1 multiple interactions EXP 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA1 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA1 protein] CTD PMID:10964929 NCBI chr 2:24,491,254...24,770,702
Ensembl chr 2:24,491,254...24,770,702
JBrowse link
G NCOA2 nuclear receptor coactivator 2 multiple interactions EXP 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA2 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA2 protein] CTD PMID:10964929 NCBI chr 8:70,109,770...70,405,390
Ensembl chr 8:70,109,782...70,403,808
JBrowse link
G NID1 nidogen 1 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of NID1 mRNA CTD PMID:23626723 NCBI chr 1:235,975,830...236,065,092
Ensembl chr 1:235,975,830...236,065,109
JBrowse link
G NR1I2 nuclear receptor subfamily 1 group I member 2 multiple interactions EXP 4-tert-octylphenol binds to and results in increased activity of NR1I2 protein; p-tert-amylphenol binds to and results in increased activity of NR1I2 protein CTD PMID:33049310 NCBI chr 3:119,782,101...119,818,487
Ensembl chr 3:119,780,484...119,818,487
JBrowse link
G NR1I3 nuclear receptor subfamily 1 group I member 3 increases activity EXP 4-tert-octylphenol results in increased activity of NR1I3 protein; p-tert-amylphenol results in increased activity of NR1I3 protein CTD PMID:26231822 PMID:28927721 NCBI chr 1:161,229,666...161,238,623
Ensembl chr 1:161,229,666...161,238,244
JBrowse link
G NR2F6 nuclear receptor subfamily 2 group F member 6 increases expression ISO 4-tert-octylphenol results in increased expression of NR2F6 mRNA CTD PMID:17011747 NCBI chr19:17,231,883...17,245,919
Ensembl chr19:17,231,883...17,245,919
JBrowse link
G OCLN occludin decreases expression ISO 4-tert-octylphenol results in decreased expression of OCLN protein CTD PMID:15082077 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
JBrowse link
G OR10H1 olfactory receptor family 10 subfamily H member 1 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of OR10H1 mRNA CTD PMID:23626723 NCBI chr19:15,804,549...15,815,664
Ensembl chr19:15,804,549...15,815,664
JBrowse link
G OR2T10 olfactory receptor family 2 subfamily T member 10 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of OR2T10 mRNA CTD PMID:23626723 NCBI chr 1:248,590,487...248,597,700
Ensembl chr 1:248,590,487...248,597,700
JBrowse link
G OXT oxytocin/neurophysin I prepropeptide increases expression ISO 4-tert-octylphenol results in increased expression of OXT mRNA CTD PMID:23664861 NCBI chr20:3,068,871...3,072,517
Ensembl chr20:3,071,620...3,072,517
JBrowse link
G OXTR oxytocin receptor increases expression ISO 4-tert-octylphenol results in increased expression of OXTR mRNA; 4-tert-octylphenol results in increased expression of OXTR protein CTD PMID:23664861 NCBI chr 3:8,750,381...8,769,613
Ensembl chr 3:8,750,381...8,769,628
JBrowse link
G PDIA4 protein disulfide isomerase family A member 4 increases expression ISO 4-tert-octylphenol results in increased expression of PDIA4 mRNA CTD PMID:17011747 NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662
JBrowse link
G PFKM phosphofructokinase, muscle decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of PFKM mRNA
4-tert-octylphenol results in increased expression of PFKM mRNA
CTD PMID:17011747 NCBI chr12:48,105,353...48,146,404
Ensembl chr12:48,105,139...48,146,404
JBrowse link
G PGR progesterone receptor decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of PGR mRNA
4-tert-octylphenol results in increased expression of PGR mRNA
CTD PMID:14763995 PMID:17033158 PMID:30061528 NCBI chr11:101,029,624...101,130,681
Ensembl chr11:101,029,624...101,129,813
JBrowse link
G POU5F1 POU class 5 homeobox 1 increases expression ISO 4-tert-octylphenol results in increased expression of POU5F1 mRNA CTD PMID:20615461 NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
JBrowse link
G PPFIA4 PTPRF interacting protein alpha 4 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of PPFIA4 mRNA CTD PMID:23626723 NCBI chr 1:203,026,491...203,078,736
Ensembl chr 1:203,026,498...203,078,740
JBrowse link
G PREB prolactin regulatory element binding increases expression ISO 4-tert-octylphenol results in increased expression of PREB mRNA CTD PMID:17011747 NCBI chr 2:27,130,756...27,134,642
Ensembl chr 2:27,130,756...27,134,666
JBrowse link
G PTGFR prostaglandin F receptor decreases expression ISO 4-tert-octylphenol results in decreased expression of PTGFR mRNA; 4-tert-octylphenol results in decreased expression of PTGFR protein CTD PMID:23664861 NCBI chr 1:78,490,974...78,540,701
Ensembl chr 1:78,303,884...78,540,701
JBrowse link
G PTPRG protein tyrosine phosphatase receptor type G decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of PTPRG mRNA
4-tert-octylphenol results in increased expression of PTPRG mRNA
CTD PMID:17011747 NCBI chr 3:61,561,571...62,297,609
Ensembl chr 3:61,561,569...62,297,609
JBrowse link
G RAC1 Rac family small GTPase 1 increases expression ISO 4-tert-octylphenol results in increased expression of RAC1 mRNA CTD PMID:17011747 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967
JBrowse link
G RBP1 retinol binding protein 1 increases expression ISO 4-tert-octylphenol results in increased expression of RBP1 mRNA CTD PMID:17011747 NCBI chr 3:139,517,438...139,539,742
Ensembl chr 3:139,517,434...139,539,829
JBrowse link
G ROPN1B rhophilin associated tail protein 1B multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of ROPN1B mRNA CTD PMID:23626723 NCBI chr 3:125,969,161...125,983,454
Ensembl chr 3:125,969,160...125,983,454
JBrowse link
G RPL6 ribosomal protein L6 decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of RPL6 mRNA
4-tert-octylphenol results in increased expression of RPL6 mRNA
CTD PMID:17011747 NCBI chr12:112,405,181...112,418,850
Ensembl chr12:112,405,189...112,418,838
JBrowse link
G RXRB retinoid X receptor beta increases activity EXP 4-tert-octylphenol results in increased activity of RXRB protein CTD PMID:18207673 NCBI chr 6:33,193,588...33,200,991
Ensembl chr 6:33,193,588...33,200,665
JBrowse link
G S100A6 S100 calcium binding protein A6 increases expression ISO 4-tert-octylphenol results in increased expression of S100A6 mRNA CTD PMID:17011747 NCBI chr 1:153,534,599...153,536,049
Ensembl chr 1:153,534,599...153,536,244
JBrowse link
G S100G S100 calcium binding protein G increases expression
decreases expression
ISO 4-tert-octylphenol results in increased expression of S100G mRNA; 4-tert-octylphenol results in increased expression of S100G protein
4-tert-octylphenol results in decreased expression of S100G mRNA; 4-tert-octylphenol results in decreased expression of S100G protein
CTD PMID:12759100 PMID:14654251 PMID:15219628 PMID:17011747 PMID:17365578 PMID:23664861 NCBI chr  X:16,649,787...16,654,674
Ensembl chr  X:16,650,158...16,654,670
JBrowse link
G SBSPON somatomedin B and thrombospondin type 1 domain containing multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of SBSPON mRNA CTD PMID:23626723 NCBI chr 8:73,063,077...73,093,178
Ensembl chr 8:73,064,543...73,124,088
JBrowse link
G SCD stearoyl-CoA desaturase decreases expression ISO 4-tert-octylphenol results in decreased expression of SCD mRNA CTD PMID:26164745 NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826
JBrowse link
G SDR16C5 short chain dehydrogenase/reductase family 16C member 5 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of SDR16C5 mRNA CTD PMID:23626723 NCBI chr 8:56,300,005...56,320,560
Ensembl chr 8:56,300,005...56,320,776
JBrowse link
G SERF1A small EDRK-rich factor 1A multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of SERF1A mRNA CTD PMID:23626723 NCBI chr 5:70,900,669...70,918,530
Ensembl chr 5:70,025,247...70,043,113
Ensembl chr 5:70,025,247...70,043,113
JBrowse link
G SF3B4 splicing factor 3b subunit 4 increases expression ISO 4-tert-octylphenol results in increased expression of SF3B4 mRNA CTD PMID:17011747 NCBI chr 1:149,923,317...149,927,803
Ensembl chr 1:149,923,317...149,927,803
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 increases expression ISO 4-tert-octylphenol results in increased expression of SHMT1 mRNA; 4-tert-octylphenol results in increased expression of SHMT1 protein CTD PMID:30487447 NCBI chr17:18,327,873...18,363,560
Ensembl chr17:18,327,860...18,363,563
JBrowse link
G SLC12A7 solute carrier family 12 member 7 increases expression ISO 4-tert-octylphenol results in increased expression of SLC12A7 mRNA CTD PMID:17011747 NCBI chr 5:1,050,384...1,155,887
Ensembl chr 5:1,050,384...1,112,063
JBrowse link
G SLC40A1 solute carrier family 40 member 1 increases expression ISO 4-tert-octylphenol results in increased expression of SLC40A1 mRNA CTD PMID:17011747 NCBI chr 2:189,560,590...189,580,811
Ensembl chr 2:189,560,590...189,583,758
JBrowse link
G SLC7A6OS solute carrier family 7 member 6 opposite strand increases expression ISO 4-tert-octylphenol results in increased expression of SLC7A6OS mRNA CTD PMID:17011747 NCBI chr16:68,298,034...68,310,948
Ensembl chr16:68,284,503...68,310,946
JBrowse link
G SLC7A7 solute carrier family 7 member 7 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of SLC7A7 mRNA CTD PMID:23626723 NCBI chr14:22,773,222...22,819,796
Ensembl chr14:22,773,222...22,829,820
JBrowse link
G SLC8A1 solute carrier family 8 member A1 decreases expression ISO 4-tert-octylphenol results in decreased expression of SLC8A1 mRNA CTD PMID:30061528 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053
JBrowse link
G SNAI1 snail family transcriptional repressor 1 increases expression
multiple interactions
EXP 4-tert-octylphenol results in increased expression of SNAI1 protein
Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of SNAI1 protein]
CTD PMID:27145024 NCBI chr20:49,982,980...49,988,886
Ensembl chr20:49,982,980...49,988,886
JBrowse link
G SNAI2 snail family transcriptional repressor 2 multiple interactions
increases expression
EXP Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of SNAI2 protein] CTD PMID:27145024 NCBI chr 8:48,917,598...48,921,429
Ensembl chr 8:48,917,598...48,921,740
JBrowse link
G SOAT1 sterol O-acyltransferase 1 increases expression ISO 4-tert-octylphenol results in increased expression of SOAT1 mRNA CTD PMID:17011747 NCBI chr 1:179,293,719...179,358,680
Ensembl chr 1:179,293,714...179,358,680
JBrowse link
G SOSTDC1 sclerostin domain containing 1 decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of SOSTDC1 mRNA
4-tert-octylphenol results in increased expression of SOSTDC1 mRNA
CTD PMID:17011747 NCBI chr 7:16,461,481...16,465,738
Ensembl chr 7:16,461,481...16,530,580
JBrowse link
G SP1 Sp1 transcription factor multiple interactions ISO [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of SP1 mRNA CTD PMID:29029336 NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446
JBrowse link
G SPRR2A small proline rich protein 2A increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2A mRNA CTD PMID:20438831 NCBI chr 1:153,056,120...153,057,512
Ensembl chr 1:153,056,120...153,057,512
JBrowse link
G SPRR2B small proline rich protein 2B increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2B mRNA CTD PMID:20438831 NCBI chr 1:153,070,226...153,071,611
Ensembl chr 1:153,070,224...153,070,840
JBrowse link
G SPRR2D small proline rich protein 2D increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2D mRNA CTD PMID:20438831 NCBI chr 1:153,039,732...153,041,120
Ensembl chr 1:153,039,732...153,041,931
JBrowse link
G SPRR2E small proline rich protein 2E increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2E mRNA CTD PMID:20438831 NCBI chr 1:153,093,135...153,094,526
Ensembl chr 1:153,093,135...153,106,184
JBrowse link
G SPRR2F small proline rich protein 2F increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2F mRNA CTD PMID:20438831 NCBI chr 1:153,112,121...153,119,468
Ensembl chr 1:153,112,121...153,113,516
JBrowse link
G SPRR2G small proline rich protein 2G increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2G mRNA CTD PMID:20438831 NCBI chr 1:153,149,582...153,195,377
Ensembl chr 1:153,149,582...153,150,890
JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 decreases expression ISO 4-tert-octylphenol results in decreased expression of SREBF1 mRNA; 4-tert-octylphenol results in decreased expression of SREBF1 protein CTD PMID:26164745 NCBI chr17:17,811,334...17,837,017
Ensembl chr17:17,810,399...17,837,002
JBrowse link
G STAR steroidogenic acute regulatory protein multiple interactions
decreases expression
ISO [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of STAR mRNA
4-tert-octylphenol results in decreased expression of STAR mRNA
CTD PMID:17696135 PMID:29029336 NCBI chr 8:38,142,700...38,150,952
Ensembl chr 8:38,142,700...38,150,992
JBrowse link
G STAT1 signal transducer and activator of transcription 1 increases expression
decreases expression
ISO 4-tert-octylphenol results in increased expression of STAT1 mRNA
4-tert-octylphenol results in decreased expression of STAT1 mRNA
CTD PMID:17011747 NCBI chr 2:190,968,989...191,014,197
Ensembl chr 2:190,908,460...191,020,960
JBrowse link
G TCF21 transcription factor 21 decreases expression
increases expression
ISO 4-tert-octylphenol results in decreased expression of TCF21 mRNA
4-tert-octylphenol results in increased expression of TCF21 mRNA
CTD PMID:17011747 NCBI chr 6:133,889,113...133,895,537
Ensembl chr 6:133,889,113...133,895,553
JBrowse link
G TCF4 transcription factor 4 increases expression ISO 4-tert-octylphenol results in increased expression of TCF4 mRNA CTD PMID:17011747 NCBI chr18:55,222,185...55,635,957
Ensembl chr18:55,222,185...55,664,787
JBrowse link
G TFF2 trefoil factor 2 increases expression ISO 4-tert-octylphenol results in increased expression of TFF2 mRNA CTD PMID:17011747 NCBI chr21:42,346,357...42,350,994
Ensembl chr21:42,346,357...42,350,997
JBrowse link
G TGFB2 transforming growth factor beta 2 decreases expression ISO 4-tert-octylphenol results in decreased expression of TGFB2 protein CTD PMID:18065773 NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
JBrowse link
G TGFBI transforming growth factor beta induced increases expression
decreases expression
ISO 4-tert-octylphenol results in increased expression of TGFBI mRNA
4-tert-octylphenol results in decreased expression of TGFBI mRNA
CTD PMID:17011747 NCBI chr 5:136,028,988...136,063,818
Ensembl chr 5:136,028,988...136,063,818
JBrowse link
G THRA thyroid hormone receptor alpha multiple interactions EXP p-tert-amylphenol binds to and results in increased activity of THRA protein CTD PMID:33049310 NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867
JBrowse link
G TP53 tumor protein p53 increases expression ISO 4-tert-octylphenol results in increased expression of TP53 mRNA CTD PMID:17011747 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
JBrowse link
G TPD52L2 TPD52 like 2 increases expression
decreases expression
ISO 4-tert-octylphenol results in increased expression of TPD52L2 mRNA
4-tert-octylphenol results in decreased expression of TPD52L2 mRNA
CTD PMID:17011747 NCBI chr20:63,865,247...63,891,538
Ensembl chr20:63,865,228...63,891,545
JBrowse link
G TPP1 tripeptidyl peptidase 1 increases expression ISO 4-tert-octylphenol results in increased expression of TPP1 mRNA CTD PMID:17011747 NCBI chr11:6,612,768...6,619,422
Ensembl chr11:6,612,768...6,619,448
JBrowse link
G TRMT9B tRNA methyltransferase 9B (putative) multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of TRMT9B mRNA CTD PMID:23626723 NCBI chr 8:12,945,673...13,029,777
Ensembl chr 8:12,945,642...13,031,503
JBrowse link
G TRPV5 transient receptor potential cation channel subfamily V member 5 affects expression ISO 4-tert-octylphenol affects the expression of TRPV5 mRNA; 4-tert-octylphenol affects the expression of TRPV5 protein CTD PMID:30061528 NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746
JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 affects expression
multiple interactions
ISO 4-tert-octylphenol affects the expression of TRPV6 mRNA; 4-tert-octylphenol affects the expression of TRPV6 protein
Fulvestrant promotes the reaction [4-tert-octylphenol results in increased expression of TRPV6 mRNA]
CTD PMID:30061528 NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745
JBrowse link
G UGT2B15 UDP glucuronosyltransferase family 2 member B15 increases glucuronidation EXP UGT2B15 protein results in increased glucuronidation of 4-tert-octylphenol CTD PMID:28500425 NCBI chr 4:68,646,597...68,670,652
Ensembl chr 4:68,646,597...68,670,652
JBrowse link
G UGT2B7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation EXP UGT2B7 protein results in increased glucuronidation of 4-tert-octylphenol CTD PMID:28500425 NCBI chr 4:69,051,375...69,112,987
Ensembl chr 4:69,051,363...69,112,987
JBrowse link
G VEGFA vascular endothelial growth factor A multiple interactions
increases secretion
EXP 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein] CTD PMID:18252963 NCBI chr 6:43,770,209...43,786,487
Ensembl chr 6:43,770,184...43,786,487
JBrowse link
G VIPR1 vasoactive intestinal peptide receptor 1 multiple interactions EXP [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of VIPR1 mRNA CTD PMID:23626723 NCBI chr 3:42,489,299...42,537,573
Ensembl chr 3:42,489,299...42,537,573
JBrowse link
G ZHX1 zinc fingers and homeoboxes 1 increases expression ISO 4-tert-octylphenol results in increased expression of ZHX1 mRNA CTD PMID:17011747 NCBI chr 8:123,248,456...123,275,541
Ensembl chr 8:123,248,451...123,275,541
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 24775
    role 24693
      chemical role 22996
        environmental contaminant 20077
          benzene 6001
            alkylbenzene 3497
              p-tert-Amylphenol 159
Path 2
Term Annotations click to browse term
  CHEBI ontology 24775
    subatomic particle 24735
      composite particle 24735
        hadron 24735
          baryon 24735
            nucleon 24735
              atomic nucleus 24735
                atom 24735
                  main group element atom 24601
                    main group molecular entity 24601
                      s-block molecular entity 23907
                        hydrogen molecular entity 23745
                          hydrides 21962
                            organic hydride 21455
                              organic fundamental parent 21455
                                hydrocarbon 21134
                                  cyclic hydrocarbon 19952
                                    monocyclic hydrocarbon 6172
                                      annulene 6001
                                        aromatic annulene 6001
                                          benzene 6001
                                            alkylbenzene 3497
                                              p-tert-Amylphenol 159
paths to the root