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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:p-tert-Amylphenol
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Accession:CHEBI:35096 term browser browse the term
Definition:An alkylbenzene that has formula C11H16O.
Synonyms:related_synonym: 4-(1,1,3,3-Tetramethylbutyl)phenol;   4-(1,1,3,3-Tetramethylbutyl)phenol (ACD/Name 4.0);   4-(2-methylbutan-2-yl)phenol;   4-Tert-Octylphenol;   4-t-Amylphenol;   4-tert-Pentylphenol;   Formula=C11H16O;   InChI=1S/C11H16O/c1-4-11(2,3)9-5-7-10(12)8-6-9/h5-8,12H,4H2,1-3H3;   InChIKey=NRZWYNLTFLDQQX-UHFFFAOYSA-N;   Octylphenol pt;   Para-tert-Octylphenol;   SMILES=CCC(C)(C)c1ccc(O)cc1;   Tert-Octylphenol, flaked;   p-(1,1,3,3-Tetramethylbutyl)phenol;   p-(Tert-octyl)-Phenol;   p-Octylphenol;   p-Octylphenol (VAN);   p-Terc.oktylfenol;   p-Terc.oktylfenol(Czech);   p-tert-Octylphenol
 xref: CAS:140-66-9;   CAS:80-46-6;   HMDB:HMDB0013825;   KEGG:C14226
 xref_mesh: MESH:C019566


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p-tert-Amylphenol term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha decreases expression EXP 4-tert-octylphenol results in decreased expression of ACACA mRNA CTD PMID:26164745 NCBI chr10:71,519,392...71,719,910
Ensembl chr10:71,536,533...71,719,910
JBrowse link
G Afap1l2 actin filament associated protein 1-like 2 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of AFAP1L2 mRNA CTD PMID:23626723 NCBI chr 1:277,730,760...277,827,299
Ensembl chr 1:277,730,760...277,827,269
JBrowse link
G Ap1b1 adaptor related protein complex 1 subunit beta 1 increases expression EXP 4-tert-octylphenol results in increased expression of AP1B1 mRNA CTD PMID:17011747 NCBI chr14:85,230,652...85,281,806
Ensembl chr14:85,230,648...85,281,803
JBrowse link
G Ar androgen receptor affects binding
decreases activity
decreases expression
multiple interactions
EXP
ISO
p-tert-amylphenol binds to AR protein
4-tert-octylphenol binds to AR protein
4-tert-octylphenol results in decreased activity of AR protein
4-tert-octylphenol results in decreased expression of AR protein
4-tert-octylphenol results in decreased expression of AR mRNA
4-tert-octylphenol inhibits the reaction [Metribolone results in increased activity of AR protein]; 4-tert-octylphenol inhibits the reaction [Stanozolol binds to and results in increased activity of AR protein]
CTD PMID:10822019 PMID:12161000 PMID:14565775 PMID:18294747 PMID:18324785 PMID:21463676 PMID:26867867 PMID:29162470 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 increases expression EXP 4-tert-octylphenol results in increased expression of ARIH2 mRNA CTD PMID:17011747 NCBI chr 8:117,387,004...117,446,085
Ensembl chr 8:117,387,010...117,446,019
JBrowse link
G Atf4 activating transcription factor 4 increases expression
decreases expression
EXP 4-tert-octylphenol results in increased expression of ATF4 mRNA
4-tert-octylphenol results in decreased expression of ATF4 mRNA
CTD PMID:17011747 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 increases expression EXP 4-tert-octylphenol results in increased expression of ATP1B3 mRNA CTD PMID:17011747 NCBI chr 8:104,190,032...104,221,342
Ensembl chr 8:104,190,032...104,221,342
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 increases expression EXP 4-tert-octylphenol results in increased expression of ATP2B1 mRNA CTD PMID:17011747 NCBI chr 7:41,114,606...41,223,138
Ensembl chr 7:41,114,697...41,220,579
JBrowse link
G B2m beta-2 microglobulin increases expression EXP 4-tert-octylphenol results in increased expression of B2M mRNA CTD PMID:17011747 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G B3gnt3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of B3GNT3 mRNA CTD PMID:23626723 NCBI chr16:20,123,948...20,133,482
Ensembl chr16:20,123,948...20,133,322
JBrowse link
G Bnip3l BCL2 interacting protein 3 like decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of BNIP3L mRNA
4-tert-octylphenol results in increased expression of BNIP3L mRNA
CTD PMID:17011747 NCBI chr15:43,643,897...43,667,123
Ensembl chr15:43,643,897...43,667,029
JBrowse link
G C3 complement C3 increases expression EXP 4-tert-octylphenol results in increased expression of C3 mRNA; 4-tert-octylphenol results in increased expression of C3 protein CTD PMID:10822019 PMID:11086226 PMID:17011747 NCBI chr 9:9,721,137...9,747,084
Ensembl chr 9:9,721,105...9,747,167
JBrowse link
G Casp3 caspase 3 multiple interactions ISO 4-tert-octylphenol results in increased expression of and results in increased activity of CASP3 protein; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of and results in increased activity of CASP3 protein CTD PMID:29029336 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Ccbe1 collagen and calcium binding EGF domains 1 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of CCBE1 mRNA CTD PMID:23626723 NCBI chr18:61,758,754...62,013,194
Ensembl chr18:61,759,289...61,788,863
JBrowse link
G Ccnd1 cyclin D1 increases expression
multiple interactions
ISO 4-tert-octylphenol results in increased expression of CCND1 mRNA; 4-tert-octylphenol results in increased expression of CCND1 protein
ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]
CTD PMID:24684733 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cda cytidine deaminase increases expression ISO 4-tert-octylphenol results in increased expression of CDA mRNA; 4-tert-octylphenol results in increased expression of CDA protein CTD PMID:30487447 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased expression of CDH1 protein] CTD PMID:27145024 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdh2 cadherin 2 decreases expression
multiple interactions
decreases localization
increases expression
EXP
ISO
4-tert-octylphenol results in decreased expression of CDH2 protein
Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CDH2 protein]
4-tert-octylphenol results in decreased localization of CDH2 protein
CTD PMID:15082077 PMID:27145024 NCBI chr18:8,146,971...8,366,037
Ensembl chr18:8,146,971...8,360,684
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A decreases expression ISO 4-tert-octylphenol results in decreased expression of CDKN1A mRNA CTD PMID:24684733 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression EXP 4-tert-octylphenol results in decreased expression of CEBPA mRNA CTD PMID:26164745 NCBI chr 1:91,363,492...91,366,164
Ensembl chr 1:91,363,492...91,366,164
JBrowse link
G Cldn5 claudin 5 increases expression EXP 4-tert-octylphenol results in increased expression of CLDN5 mRNA CTD PMID:17011747 NCBI chr11:86,356,292...86,357,718
Ensembl chr11:86,356,294...86,357,718
JBrowse link
G Clu clusterin decreases expression EXP 4-tert-octylphenol results in decreased expression of CLU mRNA CTD PMID:10822019 PMID:14689164 NCBI chr15:42,626,612...42,665,858
Ensembl chr15:42,640,146...42,665,857
JBrowse link
G Col14a1 collagen type XIV alpha 1 chain multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of COL14A1 mRNA CTD PMID:23626723 NCBI chr 7:95,054,877...95,274,073
Ensembl chr 7:95,074,236...95,273,298
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression EXP 4-tert-octylphenol results in increased expression of COL1A2 mRNA CTD PMID:17011747 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression EXP 4-tert-octylphenol results in increased expression of CRABP2 mRNA CTD PMID:17011747 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased phosphorylation of CREB1 protein; Wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in increased phosphorylation of CREB1 protein] CTD PMID:23626723 NCBI chr 9:71,229,753...71,298,994
Ensembl chr 9:71,230,108...71,293,435
JBrowse link
G Csf1r colony stimulating factor 1 receptor multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of CSF1R mRNA CTD PMID:23626723 NCBI chr18:56,414,493...56,458,300
Ensembl chr18:56,414,488...56,458,300
JBrowse link
G Ctsb cathepsin B increases expression
multiple interactions
ISO 4-tert-octylphenol results in increased expression of CTSB mRNA; 4-tert-octylphenol results in increased expression of CTSB protein
ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB protein]
CTD PMID:23219593 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsd cathepsin D increases expression
multiple interactions
ISO 4-tert-octylphenol results in increased expression of CTSD mRNA; 4-tert-octylphenol results in increased expression of CTSD protein
ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CTSD mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of CTSD mRNA]
CTD PMID:23219593 NCBI chr 1:215,541,570...215,553,446
Ensembl chr 1:215,541,542...215,553,451
JBrowse link
G Cycs cytochrome c, somatic increases expression EXP 4-tert-octylphenol results in increased expression of CYCS mRNA CTD PMID:17011747 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases expression
multiple interactions
ISO 4-tert-octylphenol results in decreased expression of CYP11A1 mRNA; 4-tert-octylphenol results in decreased expression of CYP11A1 protein
[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP11A1 mRNA
CTD PMID:17696135 PMID:29029336 NCBI chr 8:62,798,317...62,809,848
Ensembl chr 8:62,779,875...62,809,893
JBrowse link
G Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of CYP17A1 mRNA
4-tert-octylphenol results in decreased expression of CYP17A1 mRNA
CTD PMID:17696135 PMID:29029336 NCBI chr 1:266,422,127...266,429,947
Ensembl chr 1:266,422,132...266,428,239
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 mRNA; [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of CYP19A1 protein
4-tert-octylphenol results in decreased expression of CYP19A1 mRNA
CTD PMID:29029336 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases response to substance ISO CYP1A1 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 increases response to substance ISO CYP2C9 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 NCBI chr 1:257,676,172...258,004,428
Ensembl chr 1:257,970,345...258,004,434
JBrowse link
G Cyp2c6v1 cytochrome P450, family 2, subfamily C, polypeptide 6, variant 1 increases response to substance ISO CYP2C19 gene SNP results in increased susceptibility to 4-tert-octylphenol CTD PMID:23555028 NCBI chr 1:147,713,879...147,814,410
Ensembl chr 1:147,713,892...147,888,007
JBrowse link
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 increases expression EXP 4-tert-octylphenol results in increased expression of CYP4A22 mRNA CTD PMID:17011747 NCBI chr 5:134,492,734...134,507,158
Ensembl chr 5:134,492,756...134,507,154
JBrowse link
G Dio2 iodothyronine deiodinase 2 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DIO2 mRNA CTD PMID:23626723 NCBI chr 6:114,475,156...114,489,443
Ensembl chr 6:114,476,142...114,476,723
JBrowse link
G Dnmt3a DNA methyltransferase 3 alpha multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3A mRNA; [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3A protein; Wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3A protein] CTD PMID:23626723 NCBI chr 6:28,205,375...28,346,052
Ensembl chr 6:28,235,695...28,340,577
JBrowse link
G Dnmt3b DNA methyltransferase 3 beta multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B mRNA; [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B protein; Wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3B protein] CTD PMID:23626723 NCBI chr 3:149,131,541...149,170,061
Ensembl chr 3:149,131,785...149,208,786
JBrowse link
G Dnmt3l DNA methyltransferase 3 like multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3L mRNA; [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3L protein; Wortmannin inhibits the reaction [[4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of DNMT3L protein] CTD PMID:23626723 NCBI chr20:11,344,513...11,359,090
Ensembl chr20:11,344,514...11,359,090
JBrowse link
G Dynll1 dynein light chain LC8-type 1 decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of DYNLL1 mRNA
4-tert-octylphenol results in increased expression of DYNLL1 mRNA
CTD PMID:17011747 NCBI chr12:47,074,200...47,076,573
Ensembl chr12:47,074,200...47,076,572
JBrowse link
G Ebf2 EBF transcription factor 2 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of EBF2 mRNA CTD PMID:23626723 NCBI chr15:43,905,099...44,103,742
Ensembl chr15:43,905,099...44,103,742
JBrowse link
G Egf epidermal growth factor increases expression EXP 4-tert-octylphenol results in increased expression of EGF mRNA CTD PMID:17011747 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor increases expression EXP 4-tert-octylphenol results in increased expression of EGFR mRNA CTD PMID:17011747 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Esr1 estrogen receptor 1 affects binding
decreases expression
multiple interactions
increases activity
increases expression
ISO
EXP
4-tert-octylphenol binds to ESR1 protein; p-tert-amylphenol binds to ESR1 protein
4-tert-octylphenol results in decreased expression of ESR1 mRNA; 4-tert-octylphenol results in decreased expression of ESR1 protein
4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of ESR1 mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased expression of ESR1 mRNA]
4-tert-octylphenol results in increased activity of ESR1 protein mutant form
4-tert-octylphenol results in increased expression of ESR1 mRNA
4-tert-octylphenol binds to and results in increased activity of ESR1 protein; 4-tert-octylphenol inhibits the reaction [Estradiol binds to ESR1 protein]; 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA1 protein]; 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA2 protein]; ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CCND1 mRNA]; ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CTSB mRNA]; ESR1 mutant form inhibits the reaction [4-tert-octylphenol results in increased expression of CTSD mRNA]; p-tert-amylphenol promotes the reaction [ESR1 protein alternative form binds to ESR1 protein alternative form]
CTD PMID:10964929 PMID:11086226 PMID:11162928 PMID:11530281 PMID:11750080 PMID:12161000 PMID:12504345 PMID:12737316 PMID:17141713 PMID:19233257 PMID:19666091 PMID:19913605 PMID:23219593 PMID:23557686 PMID:24684733 PMID:25012808 PMID:27633901 PMID:29162470 PMID:30061528 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 affects binding
increases expression
multiple interactions
ISO 4-tert-octylphenol binds to ESR2 protein; p-tert-amylphenol binds to ESR2 protein
4-tert-octylphenol results in increased expression of ESR2 mRNA
4-tert-octylphenol binds to and results in increased activity of ESR2 protein; 4-tert-octylphenol inhibits the reaction [Estradiol binds to ESR2 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA1 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA2 protein]
CTD PMID:10964929 PMID:12161000 PMID:12224631 PMID:12737316 PMID:19913605 PMID:27633901 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Esrrg estrogen-related receptor gamma increases activity ISO 4-tert-octylphenol results in increased activity of ESRRG protein CTD PMID:31127318 NCBI chr13:106,063,799...106,683,353
Ensembl chr13:106,463,368...106,683,436
JBrowse link
G Fasn fatty acid synthase decreases expression EXP 4-tert-octylphenol results in decreased expression of FASN mRNA; 4-tert-octylphenol results in decreased expression of FASN protein CTD PMID:26164745 NCBI chr10:109,987,735...110,005,901
Ensembl chr10:109,987,735...110,005,901
JBrowse link
G Fcgr3a Fc fragment of IgG receptor IIIa multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of FCGR3A mRNA CTD PMID:23626723 NCBI chr13:89,385,775...89,396,047
Ensembl chr13:89,385,859...89,396,051
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP 4-tert-octylphenol results in increased expression of FOS mRNA CTD PMID:17011747 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fxyd4 FXYD domain-containing ion transport regulator 4 increases expression EXP 4-tert-octylphenol results in increased expression of FXYD4 mRNA CTD PMID:17011747 NCBI chr 4:149,984,206...149,988,744
Ensembl chr 4:149,984,206...149,988,295
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP 4-tert-octylphenol results in increased expression of GAPDH mRNA CTD PMID:10822019 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gcnt4 glucosaminyl (N-acetyl) transferase 4 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of GCNT4 mRNA CTD PMID:23626723 Ensembl chr 2:27,713,880...27,780,119 JBrowse link
G Gh1 growth hormone 1 multiple interactions
increases expression
EXP Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 mRNA]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 protein]
4-tert-octylphenol results in increased expression of GH1 mRNA; 4-tert-octylphenol results in increased expression of GH1 protein
CTD PMID:19145065 NCBI chr10:94,486,204...94,488,181
Ensembl chr10:94,486,205...94,488,180
JBrowse link
G Gja1 gap junction protein, alpha 1 decreases expression EXP 4-tert-octylphenol results in decreased expression of GJA1 protein CTD PMID:15082077 NCBI chr20:37,876,650...37,889,097
Ensembl chr20:37,876,650...37,889,089
JBrowse link
G Gmeb2 glucocorticoid modulatory element binding protein 2 increases expression
decreases expression
EXP 4-tert-octylphenol results in increased expression of GMEB2 mRNA
4-tert-octylphenol results in decreased expression of GMEB2 mRNA
CTD PMID:17011747 NCBI chr 3:176,756,006...176,791,960
Ensembl chr 3:176,753,860...176,791,960
JBrowse link
G Gnl3 G protein nucleolar 3 increases expression EXP 4-tert-octylphenol results in increased expression of GNL3 mRNA CTD PMID:17011747 NCBI chr16:7,097,580...7,103,518
Ensembl chr16:7,097,507...7,103,604
JBrowse link
G Gper1 G protein-coupled estrogen receptor 1 increases expression ISO 4-tert-octylphenol results in increased expression of GPER1 mRNA CTD PMID:29783106 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Gtf2a2 general transcription factor 2A subunit 2 increases expression EXP 4-tert-octylphenol results in increased expression of GTF2A2 mRNA CTD PMID:17011747 NCBI chr 8:76,422,341...76,435,587
Ensembl chr 8:76,422,359...76,435,473
JBrowse link
G H3f3b H3.3 histone B increases expression EXP 4-tert-octylphenol results in increased expression of H3F3B mRNA CTD PMID:17011747 NCBI chr10:104,573,666...104,575,890
Ensembl chr10:104,573,664...104,575,890
JBrowse link
G Has2 hyaluronan synthase 2 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of HAS2 mRNA CTD PMID:23626723 NCBI chr 7:96,438,046...96,464,049
Ensembl chr 7:96,438,046...96,464,049
JBrowse link
G Hist1h2bq histone cluster 1 H2B family member Q decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of HIST1H2BQ mRNA
4-tert-octylphenol results in increased expression of HIST1H2BQ mRNA
CTD PMID:17011747 NCBI chr17:43,679,925...43,689,311
Ensembl chr17:43,679,925...43,689,311
JBrowse link
G Hnf1b HNF1 homeobox B increases expression EXP 4-tert-octylphenol results in increased expression of HNF1B mRNA CTD PMID:17011747 NCBI chr10:71,159,863...71,218,902
Ensembl chr10:71,159,869...71,218,902
JBrowse link
G Hoxa10 homeobox A10 multiple interactions
decreases expression
ISO 4-tert-octylphenol inhibits the reaction [Fulvestrant results in increased expression of HOXA10 mRNA]; [Fulvestrant co-treated with 4-tert-octylphenol] results in decreased expression of HOXA10 mRNA
4-tert-octylphenol results in decreased expression of HOXA10 mRNA
CTD PMID:30061528 NCBI chr 4:82,285,940...82,295,892
Ensembl chr 4:82,285,528...82,295,470
Ensembl chr 4:82,285,528...82,295,470
JBrowse link
G Hpgd 15-hydroxyprostaglandin dehydrogenase increases expression EXP 4-tert-octylphenol results in increased expression of HPGD mRNA CTD PMID:23664861 NCBI chr16:37,457,134...37,495,758
Ensembl chr16:37,457,135...37,495,758
JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression
decreases expression
EXP 4-tert-octylphenol results in increased expression of HSD11B1 mRNA
4-tert-octylphenol results in decreased expression of HSD11B1 mRNA
CTD PMID:17011747 NCBI chr13:111,946,626...111,996,536
Ensembl chr13:111,926,442...111,972,603
JBrowse link
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 increases expression EXP 4-tert-octylphenol results in increased expression of HSD17B10 mRNA CTD PMID:17011747 NCBI chr  X:21,696,796...21,699,241
Ensembl chr  X:21,696,772...21,699,241
JBrowse link
G Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 increases expression EXP 4-tert-octylphenol results in increased expression of HSD17B7 mRNA CTD PMID:17011747 NCBI chr13:88,288,116...88,308,019
Ensembl chr13:88,288,046...88,307,988
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 decreases expression ISO 4-tert-octylphenol results in decreased expression of HSD3B1 mRNA CTD PMID:29029336
G Igf1 insulin-like growth factor 1 increases expression EXP 4-tert-octylphenol results in increased expression of IGF1 mRNA CTD PMID:17011747 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Irf1 interferon regulatory factor 1 increases expression EXP 4-tert-octylphenol results in increased expression of IRF1 mRNA CTD PMID:17011747 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Itga6 integrin subunit alpha 6 increases expression EXP 4-tert-octylphenol results in increased expression of ITGA6 mRNA CTD PMID:17011747 NCBI chr 3:58,442,904...58,515,124
Ensembl chr 3:58,443,101...58,515,124
JBrowse link
G Iyd iodotyrosine deiodinase multiple interactions ISO 4-tert-octylphenol inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] CTD PMID:33352258 NCBI chr 1:40,086,513...40,100,966
Ensembl chr 1:40,086,470...40,101,840
JBrowse link
G Kcnb2 potassium voltage-gated channel subfamily B member 2 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of KCNB2 mRNA CTD PMID:23626723 NCBI chr 5:2,975,934...3,430,837 JBrowse link
G Kcnv1 potassium voltage-gated channel modifier subfamily V member 1 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of KCNV1 mRNA CTD PMID:23626723 NCBI chr 7:84,016,864...84,023,205
Ensembl chr 7:84,015,207...84,023,316
JBrowse link
G Klf9 Kruppel-like factor 9 increases expression EXP 4-tert-octylphenol results in increased expression of KLF9 mRNA CTD PMID:17011747 NCBI chr 1:240,908,483...240,933,198
Ensembl chr 1:240,908,483...240,933,198
JBrowse link
G Klk6 kallikrein related-peptidase 6 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of KLK6 mRNA CTD PMID:23626723 NCBI chr 1:99,762,195...99,769,486
Ensembl chr 1:99,762,253...99,769,488
JBrowse link
G Lhb luteinizing hormone subunit beta decreases expression
affects expression
EXP 4-tert-octylphenol results in decreased expression of LHB protein
4-tert-octylphenol affects the expression of LHB protein
CTD PMID:15888928 PMID:17033158 NCBI chr 1:101,409,992...101,413,725
Ensembl chr 1:101,410,019...101,413,724
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor increases expression EXP 4-tert-octylphenol results in increased expression of LHCGR mRNA CTD PMID:17011747 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression ISO 4-tert-octylphenol results in decreased expression of LIF mRNA CTD PMID:30061528 NCBI chr14:84,482,652...84,500,574
Ensembl chr14:84,482,674...84,500,642
JBrowse link
G LOC102550598 small proline-rich protein 2I-like increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2G mRNA CTD PMID:20438831 NCBI chr 2:192,520,019...192,521,188
Ensembl chr 2:192,520,733...192,520,960
JBrowse link
G LOC103690286 olfactory receptor 2T29-like multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of OR2T10 mRNA CTD PMID:23626723 NCBI chr10:44,174,086...44,175,033
Ensembl chr10:44,174,086...44,175,030
JBrowse link
G Lratd2 LRAT domain containing 2 increases expression EXP 4-tert-octylphenol results in increased expression of LRATD2 mRNA CTD PMID:17011747 NCBI chr 7:101,138,188...101,142,123
Ensembl chr 7:101,139,376...101,140,308
JBrowse link
G Lsp1 lymphocyte-specific protein 1 increases expression EXP 4-tert-octylphenol results in increased expression of LSP1 mRNA CTD PMID:17011747 NCBI chr 1:215,628,750...215,662,505
Ensembl chr 1:215,628,785...215,662,504
JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 increases expression EXP 4-tert-octylphenol results in increased expression of MAP3K12 mRNA CTD PMID:17011747 NCBI chr 7:144,102,275...144,120,306
Ensembl chr 7:144,102,680...144,109,116
JBrowse link
G Mapk1 mitogen activated protein kinase 1 decreases phosphorylation
multiple interactions
ISO 4-tert-octylphenol results in decreased phosphorylation of MAPK1 protein
[Diethylhexyl Phthalate co-treated with 4-tert-octylphenol] results in decreased phosphorylation of MAPK1 protein; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK1 protein]
CTD PMID:26133781 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
ISO 4-tert-octylphenol results in decreased phosphorylation of MAPK3 protein
[Diethylhexyl Phthalate co-treated with 4-tert-octylphenol] results in decreased phosphorylation of MAPK3 protein; Fulvestrant inhibits the reaction [4-tert-octylphenol results in decreased phosphorylation of MAPK3 protein]
CTD PMID:26133781 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mecr mitochondrial trans-2-enoyl-CoA reductase increases expression EXP 4-tert-octylphenol results in increased expression of MECR mRNA CTD PMID:17011747 NCBI chr 5:150,001,281...150,027,407
Ensembl chr 5:150,001,281...150,027,049
JBrowse link
G Mt3 metallothionein 3 increases expression EXP 4-tert-octylphenol results in increased expression of MT3 mRNA CTD PMID:17011747 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139
JBrowse link
G Muc1 mucin 1, cell surface associated multiple interactions
increases expression
ISO Fulvestrant promotes the reaction [4-tert-octylphenol results in increased expression of MUC1 mRNA]
4-tert-octylphenol results in increased expression of MUC1 mRNA; 4-tert-octylphenol results in increased expression of MUC1 protein
CTD PMID:30061528 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874
JBrowse link
G Naalad2 N-acetylated alpha-linked acidic dipeptidase 2 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of NAALAD2 mRNA CTD PMID:23626723 NCBI chr 8:17,453,198...17,525,906
Ensembl chr 8:17,454,122...17,525,906
JBrowse link
G Ncoa1 nuclear receptor coactivator 1 multiple interactions ISO 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA1 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA1 protein] CTD PMID:10964929 NCBI chr 6:28,677,563...28,931,844
Ensembl chr 6:28,677,540...28,931,843
JBrowse link
G Ncoa2 nuclear receptor coactivator 2 multiple interactions ISO 4-tert-octylphenol promotes the reaction [ESR1 protein binds to NCOA2 protein]; 4-tert-octylphenol promotes the reaction [ESR2 protein binds to NCOA2 protein] CTD PMID:10964929 NCBI chr 5:5,466,544...5,696,540
Ensembl chr 5:5,616,483...5,694,598
JBrowse link
G Nid1 nidogen 1 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of NID1 mRNA CTD PMID:23626723 NCBI chr17:90,553,161...90,627,133
Ensembl chr17:90,553,394...90,627,101
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 4-tert-octylphenol results in increased activity of NR1I3 protein; p-tert-amylphenol results in increased activity of NR1I3 protein CTD PMID:26231822 PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Nr2f6 nuclear receptor subfamily 2, group F, member 6 increases expression EXP 4-tert-octylphenol results in increased expression of NR2F6 mRNA CTD PMID:17011747 NCBI chr16:19,769,968...19,777,414
Ensembl chr16:19,769,968...19,777,414
JBrowse link
G Ocln occludin decreases expression EXP 4-tert-octylphenol results in decreased expression of OCLN protein CTD PMID:15082077 NCBI chr 2:30,527,327...30,577,218
Ensembl chr 2:30,527,715...30,577,218
JBrowse link
G Olr1095 olfactory receptor 1095 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of OR10H1 mRNA CTD PMID:23626723 NCBI chr 7:15,621,989...15,622,945
Ensembl chr 7:15,621,989...15,622,945
JBrowse link
G Oxt oxytocin/neurophysin I prepropeptide increases expression EXP 4-tert-octylphenol results in increased expression of OXT mRNA CTD PMID:23664861 NCBI chr 3:123,106,694...123,107,534
Ensembl chr 3:123,106,694...123,107,534
JBrowse link
G Oxtr oxytocin receptor increases expression EXP 4-tert-octylphenol results in increased expression of OXTR mRNA; 4-tert-octylphenol results in increased expression of OXTR protein CTD PMID:23664861 NCBI chr 4:144,399,326...144,417,598
Ensembl chr 4:144,403,358...144,416,116
JBrowse link
G Pdia4 protein disulfide isomerase family A, member 4 increases expression EXP 4-tert-octylphenol results in increased expression of PDIA4 mRNA CTD PMID:17011747 NCBI chr 4:77,470,636...77,489,535
Ensembl chr 4:77,470,636...77,489,535
JBrowse link
G Pfkm phosphofructokinase, muscle increases expression
decreases expression
EXP 4-tert-octylphenol results in increased expression of PFKM mRNA
4-tert-octylphenol results in decreased expression of PFKM mRNA
CTD PMID:17011747 NCBI chr 7:139,702,066...139,722,132
Ensembl chr 7:139,685,573...139,722,132
JBrowse link
G Pgr progesterone receptor increases expression
decreases expression
EXP
ISO
4-tert-octylphenol results in increased expression of PGR mRNA
4-tert-octylphenol results in decreased expression of PGR mRNA
CTD PMID:14763995 PMID:17033158 PMID:30061528 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link
G Pou5f1 POU class 5 homeobox 1 increases expression ISO 4-tert-octylphenol results in increased expression of POU5F1 mRNA CTD PMID:20615461 NCBI chr20:3,747,231...3,751,994
Ensembl chr20:3,747,221...3,751,994
JBrowse link
G Ppfia4 PTPRF interacting protein alpha 4 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of PPFIA4 mRNA CTD PMID:23626723 NCBI chr13:51,134,831...51,183,321
Ensembl chr13:51,134,525...51,183,269
JBrowse link
G Preb prolactin regulatory element binding increases expression EXP 4-tert-octylphenol results in increased expression of PREB mRNA CTD PMID:17011747 NCBI chr 6:26,784,088...26,787,875
Ensembl chr 6:26,784,088...26,787,874
JBrowse link
G Ptgfr prostaglandin F receptor decreases expression EXP 4-tert-octylphenol results in decreased expression of PTGFR mRNA; 4-tert-octylphenol results in decreased expression of PTGFR protein CTD PMID:23664861 NCBI chr 2:257,005,813...257,039,036
Ensembl chr 2:257,005,829...257,038,105
JBrowse link
G Ptprg protein tyrosine phosphatase, receptor type, G decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of PTPRG mRNA
4-tert-octylphenol results in increased expression of PTPRG mRNA
CTD PMID:17011747 NCBI chr15:12,926,056...13,633,839
Ensembl chr15:12,926,167...13,228,607
JBrowse link
G Rac1 Rac family small GTPase 1 increases expression EXP 4-tert-octylphenol results in increased expression of RAC1 mRNA CTD PMID:17011747 NCBI chr12:13,090,316...13,111,841
Ensembl chr12:13,090,172...13,111,873
JBrowse link
G Rbp1 retinol binding protein 1 increases expression EXP 4-tert-octylphenol results in increased expression of RBP1 mRNA CTD PMID:17011747 NCBI chr 8:106,449,321...106,470,842
Ensembl chr 8:106,449,321...106,470,842
JBrowse link
G Rpl6 ribosomal protein L6 decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of RPL6 mRNA
4-tert-octylphenol results in increased expression of RPL6 mRNA
CTD PMID:17011747 NCBI chr12:40,877,578...40,882,032
Ensembl chr12:40,877,613...40,881,124
JBrowse link
G Rxrb retinoid X receptor beta increases activity ISO 4-tert-octylphenol results in increased activity of RXRB protein CTD PMID:18207673 NCBI chr20:3,822,673...3,829,138
Ensembl chr20:3,823,042...3,829,140
JBrowse link
G S100a6 S100 calcium binding protein A6 increases expression EXP 4-tert-octylphenol results in increased expression of S100A6 mRNA CTD PMID:17011747 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G S100g S100 calcium binding protein G decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of S100G mRNA; 4-tert-octylphenol results in decreased expression of S100G protein
4-tert-octylphenol results in increased expression of S100G mRNA; 4-tert-octylphenol results in increased expression of S100G protein
CTD PMID:12759100 PMID:14654251 PMID:15219628 PMID:17011747 PMID:17365578 PMID:23664861 NCBI chr  X:33,442,820...33,445,714
Ensembl chr  X:33,443,186...33,445,709
JBrowse link
G Sbspon somatomedin B and thrombospondin, type 1 domain containing multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of SBSPON mRNA CTD PMID:23626723 NCBI chr 5:2,813,004...2,847,697
Ensembl chr 5:2,813,131...2,843,483
JBrowse link
G Scd stearoyl-CoA desaturase decreases expression EXP 4-tert-octylphenol results in decreased expression of SCD mRNA CTD PMID:26164745 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Sdr16c5 short chain dehydrogenase/reductase family 16C, member 5 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of SDR16C5 mRNA CTD PMID:23626723 NCBI chr 5:16,904,926...16,930,111
Ensembl chr 5:16,904,926...16,930,075
JBrowse link
G Serf1 small EDRK-rich factor 1 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of SERF1A mRNA CTD PMID:23626723 NCBI chr 2:30,345,861...30,352,114
Ensembl chr 2:30,346,069...30,352,099
JBrowse link
G Sf3b4 splicing factor 3b, subunit 4 increases expression EXP 4-tert-octylphenol results in increased expression of SF3B4 mRNA CTD PMID:17011747 NCBI chr 2:198,312,428...198,317,180
Ensembl chr 2:198,312,428...198,317,180
JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 increases expression ISO 4-tert-octylphenol results in increased expression of SHMT1 mRNA; 4-tert-octylphenol results in increased expression of SHMT1 protein CTD PMID:30487447 NCBI chr10:47,030,813...47,059,216
Ensembl chr10:47,031,050...47,059,216
JBrowse link
G Slc12a7 solute carrier family 12 member 7 increases expression EXP 4-tert-octylphenol results in increased expression of SLC12A7 mRNA CTD PMID:17011747 NCBI chr 1:32,086,755...32,167,950
Ensembl chr 1:32,086,755...32,141,036
JBrowse link
G Slc40a1 solute carrier family 40 member 1 increases expression EXP 4-tert-octylphenol results in increased expression of SLC40A1 mRNA CTD PMID:17011747 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc7a6os solute carrier family 7, member 6 opposite strand increases expression EXP 4-tert-octylphenol results in increased expression of SLC7A6OS mRNA CTD PMID:17011747 NCBI chr19:38,180,859...38,189,523
Ensembl chr19:38,180,861...38,189,523
JBrowse link
G Slc7a7 solute carrier family 7 member 7 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of SLC7A7 mRNA CTD PMID:23626723 NCBI chr15:33,013,346...33,059,733
Ensembl chr15:33,013,504...33,051,129
JBrowse link
G Slc8a1 solute carrier family 8 member A1 decreases expression ISO 4-tert-octylphenol results in decreased expression of SLC8A1 mRNA CTD PMID:30061528 NCBI chr 6:4,244,076...4,564,262
Ensembl chr 6:4,258,991...4,520,604
JBrowse link
G Snai1 snail family transcriptional repressor 1 increases expression
multiple interactions
ISO 4-tert-octylphenol results in increased expression of SNAI1 protein
Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of SNAI1 protein]
CTD PMID:27145024 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 increases expression
multiple interactions
ISO 4-tert-octylphenol results in increased expression of SNAI2 protein
Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of SNAI2 protein]
CTD PMID:27145024 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link
G Soat1 sterol O-acyltransferase 1 increases expression EXP 4-tert-octylphenol results in increased expression of SOAT1 mRNA CTD PMID:17011747 NCBI chr13:74,035,258...74,077,759
Ensembl chr13:74,035,080...74,077,783
JBrowse link
G Sostdc1 sclerostin domain containing 1 decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of SOSTDC1 mRNA
4-tert-octylphenol results in increased expression of SOSTDC1 mRNA
CTD PMID:17011747 NCBI chr 6:55,812,820...55,816,994
Ensembl chr 6:55,812,747...55,817,066
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions ISO [Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in decreased expression of SP1 mRNA CTD PMID:29029336 NCBI chr 7:144,014,173...144,044,635
Ensembl chr 7:144,014,173...144,044,629
JBrowse link
G Sprr2d small proline-rich protein 2D increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2D mRNA CTD PMID:20438831 NCBI chr 2:192,480,676...192,481,990
Ensembl chr 2:192,481,028...192,481,273
JBrowse link
G Sprr2f small proline rich protein 2F increases expression ISO 4-tert-octylphenol results in increased expression of SPRR2F mRNA CTD PMID:20438831 NCBI chr 2:192,604,978...192,605,208 JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 decreases expression EXP 4-tert-octylphenol results in decreased expression of SREBF1 mRNA; 4-tert-octylphenol results in decreased expression of SREBF1 protein CTD PMID:26164745 NCBI chr10:46,570,996...46,593,021
Ensembl chr10:46,570,996...46,593,009
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression
multiple interactions
ISO 4-tert-octylphenol results in decreased expression of STAR mRNA
[Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with butylbenzyl phthalate co-treated with 4-nonylphenol co-treated with 4-tert-octylphenol] results in increased expression of STAR mRNA
CTD PMID:17696135 PMID:29029336 NCBI chr16:71,036,204...71,040,847
Ensembl chr16:71,036,204...71,040,847
JBrowse link
G Stat1 signal transducer and activator of transcription 1 decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of STAT1 mRNA
4-tert-octylphenol results in increased expression of STAT1 mRNA
CTD PMID:17011747 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Tcf21 transcription factor 21 decreases expression
increases expression
EXP 4-tert-octylphenol results in decreased expression of TCF21 mRNA
4-tert-octylphenol results in increased expression of TCF21 mRNA
CTD PMID:17011747 NCBI chr 1:23,906,717...23,909,576
Ensembl chr 1:23,906,717...23,909,566
JBrowse link
G Tcf4 transcription factor 4 increases expression EXP 4-tert-octylphenol results in increased expression of TCF4 mRNA CTD PMID:17011747 NCBI chr18:65,285,320...65,507,983
Ensembl chr18:65,155,685...65,507,977
JBrowse link
G Tff2 trefoil factor 2 increases expression EXP 4-tert-octylphenol results in increased expression of TFF2 mRNA CTD PMID:17011747 NCBI chr20:9,872,669...9,876,008
Ensembl chr20:9,872,680...9,876,008
JBrowse link
G Tgfb2 transforming growth factor, beta 2 decreases expression ISO 4-tert-octylphenol results in decreased expression of TGFB2 protein CTD PMID:18065773 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfbi transforming growth factor, beta induced increases expression
decreases expression
EXP 4-tert-octylphenol results in increased expression of TGFBI mRNA
4-tert-octylphenol results in decreased expression of TGFBI mRNA
CTD PMID:17011747 NCBI chr17:8,400,123...8,429,338
Ensembl chr17:8,400,146...8,429,338
JBrowse link
G Tp53 tumor protein p53 increases expression EXP 4-tert-octylphenol results in increased expression of TP53 mRNA CTD PMID:17011747 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpd52l2 TPD52 like 2 increases expression
decreases expression
EXP 4-tert-octylphenol results in increased expression of TPD52L2 mRNA
4-tert-octylphenol results in decreased expression of TPD52L2 mRNA
CTD PMID:17011747 NCBI chr 3:176,989,333...177,009,425
Ensembl chr 3:176,989,672...177,008,419
JBrowse link
G Tpp1 tripeptidyl peptidase 1 increases expression EXP 4-tert-octylphenol results in increased expression of TPP1 mRNA CTD PMID:17011747 NCBI chr 1:170,588,036...170,594,159
Ensembl chr 1:170,588,035...170,594,168
JBrowse link
G Trmt9b tRNA methyltransferase 9B (putative) multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in increased expression of TRMT9B mRNA CTD PMID:23626723 NCBI chr16:59,316,145...59,368,559
Ensembl chr16:59,317,699...59,366,824
JBrowse link
G Trpv5 transient receptor potential cation channel, subfamily V, member 5 affects expression ISO 4-tert-octylphenol affects the expression of TRPV5 mRNA; 4-tert-octylphenol affects the expression of TRPV5 protein CTD PMID:30061528 NCBI chr 4:70,947,615...70,974,004
Ensembl chr 4:70,947,717...70,974,006
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions
affects expression
ISO Fulvestrant promotes the reaction [4-tert-octylphenol results in increased expression of TRPV6 mRNA]
4-tert-octylphenol affects the expression of TRPV6 mRNA; 4-tert-octylphenol affects the expression of TRPV6 protein
CTD PMID:30061528 NCBI chr 4:70,918,631...70,934,291
Ensembl chr 4:70,918,632...70,934,295
JBrowse link
G Ugt2b7 UDP glucuronosyltransferase family 2 member B7 increases glucuronidation ISO UGT2B7 protein results in increased glucuronidation of 4-tert-octylphenol CTD PMID:28500425 NCBI chr14:22,597,103...22,619,968 JBrowse link
G Vegfa vascular endothelial growth factor A increases secretion
multiple interactions
ISO 4-tert-octylphenol results in increased secretion of VEGFA protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; Fulvestrant inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; SB 203580 inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]; Wortmannin inhibits the reaction [4-tert-octylphenol results in increased secretion of VEGFA protein]
CTD PMID:18252963 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vipr1 vasoactive intestinal peptide receptor 1 multiple interactions ISO [4-tert-octylphenol co-treated with 4-nonylphenol] results in decreased expression of VIPR1 mRNA CTD PMID:23626723 NCBI chr 8:130,283,453...130,313,431 JBrowse link
G Zhx1 zinc fingers and homeoboxes 1 increases expression EXP 4-tert-octylphenol results in increased expression of ZHX1 mRNA CTD PMID:17011747 NCBI chr 7:97,915,280...97,944,787
Ensembl chr 7:97,915,581...97,944,491
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19783
    role 19728
      chemical role 19268
        environmental contaminant 18604
          benzene 5642
            alkylbenzene 3364
              p-tert-Amylphenol 151
Path 2
Term Annotations click to browse term
  CHEBI ontology 19783
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    main group molecular entity 19670
                      s-block molecular entity 19436
                        hydrogen molecular entity 19430
                          hydrides 18762
                            organic hydride 18361
                              organic fundamental parent 18361
                                hydrocarbon 18080
                                  cyclic hydrocarbon 17093
                                    monocyclic hydrocarbon 5815
                                      annulene 5642
                                        aromatic annulene 5642
                                          benzene 5642
                                            alkylbenzene 3364
                                              p-tert-Amylphenol 151
paths to the root