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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:cefpodoxime
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Accession:CHEBI:3504 term browser browse the term
Definition:A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis.
Synonyms:exact_synonym: 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Formula=C15H17N5O6S2;   InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1;   InChIKey=WYUSVOMTXWRGEK-HBWVYFAYSA-N;   SMILES=[H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1csc(N)n1)C(O)=O;   cefpodoxima;   cefpodoximum
 alt_id: CHEBI:606443
 xref: Beilstein:6021381;   CAS:80210-62-4;   DrugBank:DB01416;   KEGG:C08114;   KEGG:D07650
 xref_mesh: MESH:C053268
 xref: PMID:20606336;   PMID:20821175;   PMID:21395603;   PMID:21420838;   PMID:21455420;   PMID:21509928;   PMID:21569093;   PMID:21667000;   PMID:29017833;   Reaxys:6021381;   VSDB:2968;   Wikipedia:Cefpodoxime


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cefpodoxime term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prl prolactin increases expression ISO cefpodoxime results in increased expression of PRL protein CTD PMID:20083845 NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      biological role 19761
        antimicrobial agent 17400
          antibacterial agent 13566
            antibacterial drug 3189
              cefpodoxime 1
                cefpodoxime proxetil 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic group 18728
                              organic divalent group 18719
                                organodiyl group 18719
                                  carbonyl group 18667
                                    carbonyl compound 18667
                                      carboxylic acid 18364
                                        carboacyl group 17482
                                          univalent carboacyl group 17482
                                            carbamoyl group 17298
                                              carboxamide 17298
                                                lactam 8302
                                                  beta-lactam 794
                                                    beta-lactam antibiotic 779
                                                      cephem 545
                                                        cephalosporin 544
                                                          cefpodoxime 1
                                                            cefpodoxime proxetil 0
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