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ONTOLOGY REPORT - ANNOTATIONS


Term:cefpodoxime
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Accession:CHEBI:3504 term browser browse the term
Definition:A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis.
Synonyms:exact_synonym: 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid
 related_synonym: (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;   Formula=C15H17N5O6S2;   InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1;   InChIKey=WYUSVOMTXWRGEK-HBWVYFAYSA-N;   SMILES=[H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1csc(N)n1)C(O)=O;   cefpodoxima;   cefpodoximum
 alt_id: CHEBI:606443
 xref: Beilstein:6021381 "Beilstein";   CAS:80210-62-4 "ChemIDplus";   CAS:80210-62-4 "KEGG COMPOUND";   DrugBank:DB01416;   KEGG:C08114;   KEGG:D07650
 xref_mesh: MESH:C053268
 xref: PMID:20606336 "Europe PMC";   PMID:20821175 "Europe PMC";   PMID:21395603 "Europe PMC";   PMID:21420838 "Europe PMC";   PMID:21455420 "Europe PMC";   PMID:21509928 "Europe PMC";   PMID:21569093 "Europe PMC";   PMID:21667000 "Europe PMC";   PMID:29017833 "Europe PMC";   Reaxys:6021381 "Reaxys";   VSDB:2968;   Wikipedia:Cefpodoxime


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cefpodoxime term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Prl prolactin JBrowse link 17 39,814,236 39,824,299 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    role 19613
      biological role 19611
        antimicrobial agent 17151
          antibacterial agent 12904
            antibacterial drug 3037
              cefpodoxime 1
                cefpodoxime proxetil 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic group 18343
                              organic divalent group 18334
                                organodiyl group 18334
                                  carbonyl group 18222
                                    carbonyl compound 18222
                                      carboxylic acid 17923
                                        carboacyl group 16943
                                          univalent carboacyl group 16943
                                            carbamoyl group 16622
                                              carboxamide 16622
                                                lactam 2855
                                                  beta-lactam 711
                                                    beta-lactam antibiotic 699
                                                      cephem 539
                                                        cephalosporin 538
                                                          cefpodoxime 1
                                                            cefpodoxime proxetil 0
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