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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:fentin chloride
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Accession:CHEBI:35036 term browser browse the term
Definition:An organotin compound that is triphenylstannane in which the hydrogen attached to tin is replaced by a chloro group. A fungicide used to control blights on potatoes, leaf spot diseases on sugar beet and anthracnose on beans.
Synonyms:related_synonym: Chlorotriphenylstannane;   Chlorotriphenyltin;   Formula=C18H15ClSn;   InChI=1S/3C6H5.ClH.Sn/c3*1-2-4-6-5-3-1;;/h3*1-5H;1H;/q;;;;+1/p-1;   InChIKey=NJVOZLGKTAPUTQ-UHFFFAOYSA-M;   SMILES=Cl[Sn](c1ccccc1)(c1ccccc1)c1ccccc1;   TPTC;   Triphenylchlorostannane;   Triphenylchlorotin;   Triphenyltin chloride;   triphenylstannylium chloride
 xref: CAS:639-58-7;   KEGG:C14413;   LINCS:LSM-37196
 xref_mesh: MESH:C012594
 xref: PMID:1280083;   PMID:1677872;   PMID:19882143;   PMID:20591183;   PMID:20708649;   PMID:2084225;   PMID:22002760;   PMID:23128992;   PMID:23981671;   PMID:25045140;   PMID:7679203;   PPDB:1477;   Reaxys:524762


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fentin chloride term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anxa5 annexin A5 decreases expression
multiple interactions
ISO triphenyltin chloride results in decreased expression of ANXA5 protein
Tretinoin promotes the reaction [triphenyltin chloride results in decreased expression of ANXA5 protein]
CTD PMID:30806631 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 increases expression ISO triphenyltin chloride results in increased expression of CYP19A1 mRNA CTD PMID:15941851 NCBI chr 8:58,744,849...58,772,408
Ensembl chr 8:58,744,849...58,772,408
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase decreases expression
multiple interactions
ISO triphenyltin chloride results in decreased expression of GAPDH protein
triphenyltin chloride promotes the reaction [Tretinoin results in decreased expression of GAPDH protein]
CTD PMID:30806631 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Hat1 histone acetyltransferase 1 increases activity EXP triphenyltin chloride results in increased activity of HAT1 protein CTD PMID:15603928 NCBI chr 3:58,022,395...58,070,067
Ensembl chr 3:58,022,238...58,070,068
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions
increases expression
ISO 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein]; Cycloheximide promotes the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA]; Glycyrrhetinic Acid inhibits the reaction [triphenyltin chloride results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [triphenyltin chloride results in increased expression of and results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA]; triphenyltin chloride results in increased expression of and results in increased activity of HSD11B2 protein CTD PMID:31927052 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 increases expression
increases activity
ISO triphenyltin chloride results in increased expression of HSD17B1 mRNA
triphenyltin chloride results in increased activity of HSD17B1 protein
CTD PMID:16513093 NCBI chr10:88,987,558...88,989,758
Ensembl chr10:88,987,558...88,989,757
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO Lipopolysaccharides promotes the reaction [triphenyltin chloride results in increased expression of IL1B mRNA] CTD PMID:16687389 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions ISO Lipopolysaccharides promotes the reaction [triphenyltin chloride results in increased expression of IL6 mRNA] CTD PMID:16687389 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 multiple interactions
decreases expression
ISO Tretinoin promotes the reaction [triphenyltin chloride results in decreased expression of NME2 protein] CTD PMID:30806631 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma multiple interactions
increases activity
ISO diphenyltin chloride inhibits the reaction [triphenyltin chloride binds to PPARG protein]; tetrabutyltin inhibits the reaction [triphenyltin chloride binds to PPARG protein]; tributyltin inhibits the reaction [triphenyltin chloride binds to PPARG protein]; triphenyltin chloride binds to and results in increased activity of PPARG protein; triphenyltin chloride inhibits the reaction [rosiglitazone binds to PPARG protein]
triphenyltin chloride results in increased activity of PPARG protein
CTD PMID:19497422, PMID:26172262 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO RXRA protein affects the reaction [triphenyltin chloride results in increased expression of and results in increased activity of HSD11B2 protein]; RXRA protein affects the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA]; triphenyltin chloride inhibits the reaction [Alitretinoin binds to RXRA protein]; triphenyltin chloride inhibits the reaction [triphenyltin hydroxide binds to RXRA protein] CTD PMID:15941851, PMID:31927052 NCBI chr 3:6,272,560...6,295,354
Ensembl chr 3:6,211,789...6,295,908
JBrowse link
G Tnf tumor necrosis factor increases secretion ISO triphenyltin chloride results in increased secretion of TNF protein CTD PMID:8660944 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Vim vimentin decreases expression
multiple interactions
ISO triphenyltin chloride results in decreased expression of VIM protein
[Tretinoin co-treated with triphenyltin chloride] results in decreased expression of VIM mRNA; Tretinoin promotes the reaction [triphenyltin chloride results in decreased expression of VIM protein]
CTD PMID:30806631, PMID:31634547 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        agrochemical 14435
          antifungal agrochemical 7529
            fentin chloride 13
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organometallic compound 6721
                              organotin compound 1161
                                triphenylstannane 112
                                  fentin chloride 13
paths to the root

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