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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:trifluralin
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Accession:CHEBI:35027 term browser browse the term
Definition:A substituted aniline that is N,N-dipropylaniline substituted by a nitro groups at positions 2 and 6 and a trifluoromethyl group at position 4. It is an agrochemical used as a pre-emergence herbicide.
Synonyms:exact_synonym: 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)aniline
 related_synonym: 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamine;   Formula=C13H16F3N3O4;   InChI=1S/C13H16F3N3O4/c1-3-5-17(6-4-2)12-10(18(20)21)7-9(13(14,15)16)8-11(12)19(22)23/h7-8H,3-6H2,1-2H3;   InChIKey=ZSDSQXJSNMTJDA-UHFFFAOYSA-N;   SMILES=CCCN(CCC)c1c(cc(cc1[N+]([O-])=O)C(F)(F)F)[N+]([O-])=O;   alpha,alpha,alpha-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine
 xref: CAS:1582-09-8;   KEGG:C14343
 xref_mesh: MESH:D014274
 xref: PMID:21544921;   PMID:24584589;   PMID:24984475;   PMID:25277710;   PPDB:667;   Pesticides:trifluralin;   Reaxys:1893555;   Wikipedia:Trifluralin


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trifluralin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO CYP2B6 protein results in increased metabolism of and results in decreased susceptibility to Trifluralin CTD PMID:15853388 NCBI chr 1:83,163,103...83,236,615
Ensembl chr 1:83,163,079...83,236,615
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 increases expression EXP Trifluralin results in increased expression of CYP3A23-3A1 mRNA CTD PMID:14613717 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions EXP
ISO
Trifluralin binds to and results in increased activity of NR1I2 protein CTD PMID:14613717, PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO Trifluralin results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Tshb thyroid stimulating hormone subunit beta multiple interactions EXP Trifluralin results in increased expression of and results in increased secretion of TSHB protein CTD PMID:18582544 NCBI chr 2:205,207,799...205,215,199
Ensembl chr 2:205,207,799...205,212,681
JBrowse link
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 increases expression EXP Trifluralin results in increased expression of UGT1A1 mRNA CTD PMID:18582544 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a6 UDP glucuronosyltransferase family 1 member A6 increases expression EXP Trifluralin results in increased expression of UGT1A6 mRNA CTD PMID:18582544 NCBI chr 9:95,241,609...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt2b17 UDP glucuronosyltransferase family 2 member B17 increases expression EXP Trifluralin results in increased expression of UGT2B1 mRNA CTD PMID:18582544 NCBI chr14:22,724,399...22,736,148
Ensembl chr14:22,724,070...22,825,444
JBrowse link

Term paths to the root
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Term Annotations click to browse term
  CHEBI ontology 19770
    role 19718
      application 19363
        agrochemical 14429
          trifluralin 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    main group molecular entity 19655
                      s-block molecular entity 19397
                        hydrogen molecular entity 19387
                          hydrides 18419
                            organic hydride 17728
                              organic fundamental parent 17728
                                hydrocarbon 17241
                                  alkane 13606
                                    methane 9945
                                      halomethane 9945
                                        fluoromethanes 6326
                                          fluoroform 6326
                                            trifluoromethyl group 6326
                                              (trifluoromethyl)benzenes 6326
                                                trifluralin 8
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