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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Tiapamil
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Accession:CHEBI:35016 term browser browse the term
Definition:An organic amino compound that has formula C26H37NO8S2.
Synonyms:related_synonym: Formula=C26H37NO8S2;   InChI=1S/C26H37NO8S2/c1-27(15-12-20-8-10-22(32-2)24(18-20)34-4)14-6-13-26(36(28,29)16-7-17-37(26,30)31)21-9-11-23(33-3)25(19-21)35-5/h8-11,18-19H,6-7,12-17H2,1-5H3;   InChIKey=ZROUQTNYPCANTN-UHFFFAOYSA-N;   SMILES=COc1ccc(CCN(C)CCCC2(c3ccc(OC)c(OC)c3)S(=O)(=O)CCCS2(=O)=O)cc1OC
 xref: CAS:57010-31-8;   KEGG:C13765
 xref_mesh: MESH:D013976


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Tiapamil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase affects binding
multiple interactions
ISO Tiapamil Hydrochloride binds to ACHE protein
Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of ACHE protein]; Tiapamil Hydrochloride inhibits the reaction [Paraoxon results in decreased activity of ACHE protein]
CTD PMID:16036766 PMID:16193528 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Bche butyrylcholinesterase affects binding
multiple interactions
ISO Tiapamil Hydrochloride binds to BCHE protein
Tiapamil Hydrochloride inhibits the reaction [Dichlorvos results in decreased activity of BCHE protein]; Tiapamil Hydrochloride inhibits the reaction [Paraoxon results in decreased activity of BCHE protein]
CTD PMID:16036766 PMID:16193528 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Drd2 dopamine receptor D2 affects binding EXP
ISO
Tiapamil Hydrochloride binds to DRD2 protein CTD PMID:2901473 PMID:9808703 NCBI chr 8:49,708,903...49,772,888
Ensembl chr 8:49,708,927...49,772,875
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19761
      application 19471
        refrigerant 17691
          ammonia 17278
            organic amino compound 17278
              Tiapamil 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    main group molecular entity 19708
                      s-block molecular entity 19493
                        hydrogen molecular entity 19488
                          hydrides 18845
                            inorganic hydride 17691
                              pnictogen hydride 17672
                                nitrogen hydride 17545
                                  azane 17279
                                    ammonia 17278
                                      organic amino compound 17278
                                        Tiapamil 3
paths to the root