CHEBI ONTOLOGY - ANNOTATIONS
The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/ . The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/ ). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term: tetrachlorvinphos
Accession: CHEBI:35005
browse the term
Definition: An alkenyl phosphate that has formula C10H9Cl4O4P.
Synonyms: exact_synonym: (1Z)-2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl phosphate
related_synonym: (Z)-2-Chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl phosphate; 2-Chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl phosphate; Formula=C10H9Cl4O4P; Gardona; InChI=1S/C10H9Cl4O4P/c1-16-19(15,17-2)18-10(5-11)6-3-8(13)9(14)4-7(6)12/h3-5H,1-2H3/b10-5-; InChIKey=UBCKGWBNUIFUST-YHYXMXQVSA-N; SMILES=COP(=O)(OC)O\\C(c1cc(Cl)c(Cl)cc1Cl)=C/Cl; Stirofos; Stirophos
xref: Beilstein:1890909; CAS:22248-79-9; KEGG:C14513; KEGG:D05929
xref_mesh: MESH:D013751
xref: PPDB:625; VSDB:625
G
Ache
acetylcholinesterase
decreases activity
ISO
Tetrachlorvinphos metabolite results in decreased activity of ACHE protein
CTD
PMID:30625376
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
G
Ar
androgen receptor
multiple interactions
ISO
Tetrachlorvinphos inhibits the reaction [[6-fluorotestosterone co-treated with Norgestrel] binds to and results in increased activity of AR protein]
CTD
PMID:33049310
NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
G
Esr1
estrogen receptor 1
multiple interactions
ISO
Tetrachlorvinphos binds to and results in increased activity of ESR1 protein
CTD
PMID:33049310
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
G
Esr2
estrogen receptor 2
multiple interactions
ISO
Tetrachlorvinphos binds to and results in increased activity of ESR2 protein
CTD
PMID:33049310
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
G
Nr1i2
nuclear receptor subfamily 1, group I, member 2
multiple interactions
ISO
Tetrachlorvinphos binds to and results in increased activity of NR1I2 protein
CTD
PMID:21115097 PMID:33049310
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
G
Pparg
peroxisome proliferator-activated receptor gamma
multiple interactions
ISO
Tetrachlorvinphos binds to and results in increased activity of PPARG protein
CTD
PMID:33049310
NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468
G
Tp53
tumor protein p53
affects activity
ISO
Tetrachlorvinphos metabolite affects the activity of TP53 protein
CTD
PMID:35435491
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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