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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:TRAM-34
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Accession:CHEBI:34990 term browser browse the term
Definition:An organochlorine compound that has formula C22H17ClN2.
Synonyms:related_synonym: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole;   Formula=C22H17ClN2;   InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H;   InChIKey=KBFUQFVFYYBHBT-UHFFFAOYSA-N;   SMILES=Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1cccn1
 xref: KEGG:C13784
 xref_mesh: MESH:C411671


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TRAM-34 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP TRAM 34 inhibits the reaction [Paraquat results in increased expression of ACTA2 protein] CTD PMID:30036685 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO TRAM 34 results in decreased expression of ESR1 mRNA CTD PMID:20050851 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 decreases activity ISO TRAM 34 results in decreased activity of KCNN4 protein CTD PMID:20050851 NCBI chr 1:81,227,855...81,245,986
Ensembl chr 1:81,230,612...81,245,996
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO TRAM 34 binds to and results in increased activity of NR1I2 protein CTD PMID:20869355 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO TRAM 34 binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Pgr progesterone receptor increases expression ISO TRAM 34 results in increased expression of PGR mRNA CTD PMID:20050851 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      molecular entity 19784
        main group molecular entity 19672
          p-block molecular entity 19672
            halogen molecular entity 18011
              chlorine molecular entity 17793
                organochlorine compound 17466
                  TRAM-34 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      p-block molecular entity 19672
                        carbon group molecular entity 19574
                          organic molecular entity 19563
                            heteroorganic entity 19148
                              organohalogen compound 17712
                                organochlorine compound 17466
                                  TRAM-34 6
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.