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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:TRAM-34
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Accession:CHEBI:34990 term browser browse the term
Definition:An organochlorine compound that has formula C22H17ClN2.
Synonyms:related_synonym: 1-[(2-Chlorophenyl)diphenylmethyl]-1H-pyrazole;   Formula=C22H17ClN2;   InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H;   InChIKey=KBFUQFVFYYBHBT-UHFFFAOYSA-N;   SMILES=Clc1ccccc1C(c1ccccc1)(c1ccccc1)n1cccn1
 xref: KEGG:C13784
 xref_mesh: MESH:C411671


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TRAM-34 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta2 actin alpha 2, smooth muscle multiple interactions EXP TRAM 34 inhibits the reaction [Paraquat results in increased expression of ACTA2 protein] CTD PMID:30036685 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Esr1 estrogen receptor 1 decreases expression ISO TRAM 34 results in decreased expression of ESR1 mRNA CTD PMID:20050851 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 decreases activity ISO TRAM 34 results in decreased activity of KCNN4 protein CTD PMID:20050851 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO TRAM 34 binds to and results in increased activity of NR1I2 protein CTD PMID:20869355 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO TRAM 34 binds to and results in increased activity of NR1I3 protein alternative form CTD PMID:20869355 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Pgr progesterone receptor increases expression ISO TRAM 34 results in increased expression of PGR mRNA CTD PMID:20050851 NCBI chr 8:6,073,216...6,131,552
Ensembl chr 8:6,072,673...6,131,344
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19821
    chemical entity 19821
      molecular entity 19819
        main group molecular entity 19716
          p-block molecular entity 19716
            halogen molecular entity 18171
              chlorine molecular entity 18008
                organochlorine compound 17731
                  TRAM-34 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19821
    subatomic particle 19819
      composite particle 19819
        hadron 19819
          baryon 19819
            nucleon 19819
              atomic nucleus 19819
                atom 19819
                  main group element atom 19716
                    p-block element atom 19716
                      p-block molecular entity 19716
                        carbon group molecular entity 19640
                          organic molecular entity 19630
                            heteroorganic entity 19294
                              organohalogen compound 17920
                                organochlorine compound 17731
                                  TRAM-34 6
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