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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:picloram
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Accession:CHEBI:34922 term browser browse the term
Definition:A pyridinemonocarboxylic acid that is pyridine-2-carboxylic acid which is substituted by a chloro group at positions 3,5 and 6, and by an amino group at position 4. It is a systemic herbicide used to control deeply rooted herbaceous weeds and woody plants in rights-of-way, forestry, range lands, pastures, and small grain crops.
Synonyms:related_synonym: 3,5,6-trichloro-4-aminopicolinic acid;   4-Amino-3,5,6-trichloropyridine-2-carboxylic acid;   4-amino-3,5,6-trichloro-2-picolinic acid;   4-amino-3,5,6-trichloro-2-pyridinecarboxylic acid;   4-amino-3,5,6-trichloropicolinic acid;   Access;   Amdon;   Borolin;   Formula=C6H3Cl3N2O2;   Grazon;   InChI=1S/C6H3Cl3N2O2/c7-1-3(10)2(8)5(9)11-4(1)6(12)13/h(H2,10,11)(H,12,13);   InChIKey=NQQVFXUMIDALNH-UHFFFAOYSA-N;   K-Pin;   Pathway;   SMILES=C1(=C(C(C(=O)O)=NC(=C1Cl)Cl)Cl)N;   Tordon;   picloram acid;   piclorame
 xref: AGR:IND606190450;   Beilstein:0479075;   CAS:1918-02-1;   KEGG:C14310
 xref_mesh: MESH:D010846
 xref: PMID:11319026;   PMID:11368227;   PMID:12128102;   PMID:16920877;   PMID:24737019;   PMID:28281061;   PMID:28819832;   PMID:29948674;   PMID:31055199;   PMID:31254607;   PMID:31382345;   PMID:31414816;   PMID:3567404;   PMID:5153743;   PPDB:525;   Pesticides:picloram;   Wikipedia:Picloram


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picloram term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cux1 cut-like homeobox 1 multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of CUX1 gene CTD PMID:34516295 NCBI chr 5:136,276,989...136,596,429
Ensembl chr 5:136,276,989...136,596,344 		JBrowse link
G Foxo1 forkhead box O1 decreases expression
multiple interactions		 EXP Picloram results in decreased expression of FOXO1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of FOXO1 mRNA]		 CTD PMID:21318024 NCBI chr 3:52,175,758...52,257,530
Ensembl chr 3:52,175,757...52,260,642 		JBrowse link
G Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) decreases expression
multiple interactions		 EXP Picloram results in decreased expression of GRIN1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of GRIN1 mRNA]		 CTD PMID:21318024 NCBI chr 2:25,181,189...25,209,199
Ensembl chr 2:25,181,193...25,209,199 		JBrowse link
G Htr2a 5-hydroxytryptamine (serotonin) receptor 2A multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of HTR2A gene CTD PMID:34516295 NCBI chr14:74,878,314...74,944,299
Ensembl chr14:74,878,280...74,946,934 		JBrowse link
G Mettl15 methyltransferase like 15 multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of METTL15 gene CTD PMID:34516295 NCBI chr 2:108,922,642...109,111,100
Ensembl chr 2:108,922,642...109,111,093 		JBrowse link
G Msra methionine sulfoxide reductase A multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of MSRA gene CTD PMID:34516295 NCBI chr14:64,360,070...64,693,352
Ensembl chr14:64,360,074...64,693,352 		JBrowse link
G mt-Atp6 ATP synthase 6, mitochondrial multiple interactions
decreases expression		 EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of ATP6 mRNA] CTD PMID:21318024 NCBI chr MT:7,927...8,607
Ensembl chr MT:7,927...8,607 		JBrowse link
G mt-Co1 cytochrome c oxidase I, mitochondrial decreases expression
multiple interactions		 EXP Picloram results in decreased expression of COX1 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of COX1 mRNA]		 CTD PMID:21318024 NCBI chr MT:5,328...6,872
Ensembl chr MT:5,328...6,872 		JBrowse link
G mt-Cytb cytochrome b, mitochondrial multiple interactions
decreases expression		 EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide promotes the reaction [Picloram results in decreased expression of CYTB mRNA] CTD PMID:21318024 NCBI chr MT:14,145...15,288
Ensembl chr MT:14,145...15,288 		JBrowse link
G mt-Nd1 NADH dehydrogenase 1, mitochondrial multiple interactions
decreases expression		 EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of ND1 mRNA] CTD PMID:21318024 NCBI chr MT:2,751...3,707
Ensembl chr MT:2,751...3,707 		JBrowse link
G Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha increases expression EXP Picloram results in increased expression of PPARGC1A mRNA CTD PMID:21318024 NCBI chr 5:51,611,591...52,273,316
Ensembl chr 5:51,611,592...51,725,068 		JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions
decreases expression		 EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX1 mRNA] CTD PMID:21318024 NCBI chr 4:116,542,796...116,557,196
Ensembl chr 4:116,542,741...116,558,019 		JBrowse link
G Prdx2 peroxiredoxin 2 multiple interactions
decreases expression		 EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX2 mRNA] CTD PMID:21318024 NCBI chr 8:85,696,251...85,701,440
Ensembl chr 8:85,696,216...85,701,463 		JBrowse link
G Prdx3 peroxiredoxin 3 multiple interactions
decreases expression		 EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX3 mRNA] CTD PMID:21318024 NCBI chr19:60,852,504...60,862,976
Ensembl chr19:60,852,489...60,862,994 		JBrowse link
G Prdx4 peroxiredoxin 4 multiple interactions
decreases expression		 EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX4 mRNA] CTD PMID:21318024 NCBI chr  X:154,106,914...154,125,268
Ensembl chr  X:154,106,914...154,123,750 		JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression
multiple interactions		 EXP Picloram results in decreased expression of PRDX5 mRNA
arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX5 mRNA]		 CTD PMID:21318024 NCBI chr19:6,884,065...6,887,474
Ensembl chr19:6,884,065...6,887,474 		JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression		 EXP arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide inhibits the reaction [Picloram results in decreased expression of PRDX6 mRNA] CTD PMID:21318024 NCBI chr 1:161,067,682...161,078,780
Ensembl chr 1:161,067,682...161,078,789 		JBrowse link
G Tbc1d32 TBC1 domain family, member 32 multiple interactions ISO [Herbicides results in increased abundance of Picloram] which affects the methylation of TBC1D32 gene CTD PMID:34516295 NCBI chr10:55,890,389...56,106,495
Ensembl chr10:55,890,389...56,104,785 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22178
    role 22194
      application 21744
        pesticide 18859
          herbicide 15641
            picloram 18
              picloram-methyl 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 22178
    subatomic particle 22170
      composite particle 22170
        hadron 22201
          baryon 22170
            nucleon 22170
              atomic nucleus 22170
                atom 22170
                  main group element atom 22104
                    p-block element atom 22104
                      carbon group element atom 21904
                        carbon atom 21859
                          organic molecular entity 21830
                            heteroorganic entity 21482
                              organochalcogen compound 20966
                                organooxygen compound 20806
                                  carbon oxoacid 19593
                                    carboxylic acid 19589
                                      monocarboxylic acid 18952
                                        pyridinemonocarboxylic acid 418
                                          picolinic acid 41
                                            picloram 18
                                              picloram-methyl 0
paths to the root