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G |
Akr1c1 |
aldo-keto reductase family 1, member C1 |
decreases activity |
ISO |
Phenolphthalein results in decreased activity of AKR1C4 protein |
CTD |
PMID:8543560 PMID:12604236 |
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NCBI chr17:69,441,253...69,460,334
Ensembl chr17:69,441,223...69,460,321
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G |
Akr1c2 |
aldo-keto reductase family 1, member C2 |
decreases activity |
ISO |
Phenolphthalein results in decreased activity of AKR1C2 protein |
CTD |
PMID:12604236 |
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NCBI chr17:69,388,337...69,435,160
Ensembl chr17:69,388,335...69,404,341
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G |
Akr1c3 |
aldo-keto reductase family 1, member C3 |
decreases activity multiple interactions |
ISO |
Phenolphthalein results in decreased activity of AKR1C3 protein Phenolphthalein inhibits the reaction [AKR1C3 protein affects the susceptibility to oxaliplatin] |
CTD |
PMID:12604236 PMID:23933386 |
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NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
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G |
Esr1 |
estrogen receptor 1 |
affects binding multiple interactions increases activity |
ISO |
Phenolphthalein binds to ESR1 protein Phenolphthalein binds to and results in decreased activity of ESR1 protein Phenolphthalein results in increased activity of ESR1 protein |
CTD |
PMID:12598185 PMID:25012808 |
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NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
ISO |
Phenolphthalein inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate] |
CTD |
PMID:23769903 |
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NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
ISO |
Phenolphthalein binds to and results in increased activity of NR1I2 protein |
CTD |
PMID:20869355 |
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NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions |
ISO |
Phenolphthalein binds to and results in decreased activity of NR1I3 protein alternative form; Phenolphthalein binds to and results in increased activity of NR1I3 protein alternative form |
CTD |
PMID:20869355 |
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NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
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G |
Por |
cytochrome p450 oxidoreductase |
multiple interactions |
ISO |
Phenolphthalein inhibits the reaction [POR protein affects the reaction [Benzo(a)pyrene results in increased chemical synthesis of benzo(a)pyrene-7,8-dihydrodiol-9,10-epoxide-DNA]] |
CTD |
PMID:28111842 |
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NCBI chr12:23,998,411...24,017,063
Ensembl chr12:23,998,411...24,046,814
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G |
Shbg |
sex hormone binding globulin |
affects binding |
ISO |
Phenolphthalein binds to SHBG protein |
CTD |
PMID:25349334 |
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NCBI chr10:56,219,861...56,237,354
Ensembl chr10:56,219,858...56,223,245
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G |
Tyms |
thymidylate synthetase |
decreases activity |
ISO |
Phenolphthalein results in decreased activity of TYMS protein |
CTD |
PMID:21696158 |
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NCBI chr 9:121,918,875...121,931,564
Ensembl chr 9:121,918,947...121,931,564
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